# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Es2 PF09751.9 VBB25172.1 - 3.6e-68 231.3 10.2 3.6e-68 231.3 10.2 1.5 2 0 0 2 2 2 1 Nuclear protein Es2 Mst1_SARAH PF11629.8 VBB25172.1 - 0.15 12.2 1.2 14 5.8 0.2 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Bestrophin PF01062.21 VBB25173.1 - 1.1e-58 199.0 1.5 1.3e-58 198.7 1.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4024 PF13216.6 VBB25173.1 - 0.027 14.4 0.7 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) DBR1 PF05011.13 VBB25173.1 - 0.19 12.2 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Lig_chan PF00060.26 VBB25177.1 - 7.4e-49 165.4 0.3 1.8e-48 164.1 0.2 1.7 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 VBB25177.1 - 9.2e-35 119.3 0.0 2.3e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 VBB25177.1 - 2.2e-17 63.3 0.0 1.7e-16 60.4 0.0 2.4 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Tim44 PF04280.15 VBB25178.1 - 1.6e-18 67.2 0.1 2.5e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 VBB25178.1 - 7.5e-06 25.2 0.0 1.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 MBA1-like protein DSS1_SEM1 PF05160.13 VBB25179.1 - 1.6e-18 66.5 21.5 2e-18 66.2 21.5 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family R3H PF01424.22 VBB25181.1 - 3.1e-11 43.1 0.1 7.8e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 R3H domain CHASE9 PF17153.4 VBB25181.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Peptidase_M16 PF00675.20 VBB25182.1 - 9.9e-42 142.4 0.1 2.2e-41 141.3 0.1 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 VBB25182.1 - 6.4e-28 98.0 0.0 4.9e-25 88.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain UCR_TM PF02921.14 VBB25182.1 - 5.1e-13 49.3 0.5 1.3e-12 48.0 0.5 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 VBB25182.1 - 3.9e-12 45.9 0.0 9.3e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain HSP20 PF00011.21 VBB25183.1 - 4.9e-09 36.2 0.0 8.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family P53_tetramer PF07710.11 VBB25183.1 - 0.16 11.3 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 P53 tetramerisation motif Collagen PF01391.18 VBB25184.1 - 2.4e-210 680.6 696.3 8e-10 38.3 20.3 30.8 3 3 24 28 28 28 26 Collagen triple helix repeat (20 copies) C4 PF01413.19 VBB25184.1 - 1.2e-78 260.7 6.0 1.6e-39 134.7 0.4 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Ribosomal_L6 PF00347.23 VBB25185.1 - 1.6e-35 121.6 4.1 2.4e-20 73.0 1.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Pescadillo_N PF06732.11 VBB25186.1 - 2.8e-103 345.2 1.6 5.7e-103 344.2 1.6 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 VBB25186.1 - 2.1e-09 37.7 0.0 5.4e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Gti1_Pac2 PF09729.9 VBB25186.1 - 0.65 10.1 4.3 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family zf-RING_12 PF17976.1 VBB25187.1 - 7e-16 58.3 10.3 7e-16 58.3 10.3 2.7 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 VBB25187.1 - 6.8e-12 45.7 9.1 6.8e-12 45.7 9.1 4.7 4 1 1 5 5 5 1 RING/Ubox like zinc-binding domain IBR PF01485.21 VBB25187.1 - 5.1e-11 42.6 23.9 4.5e-07 30.0 2.4 5.8 3 1 3 6 6 6 2 IBR domain, a half RING-finger domain ubiquitin PF00240.23 VBB25187.1 - 0.00013 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family zf-C3HC4 PF00097.25 VBB25187.1 - 0.011 15.5 6.6 0.011 15.5 6.6 6.8 4 3 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) FARP PF01581.16 VBB25188.1 - 0.00011 22.1 8.3 2.5 9.0 0.2 3.4 3 0 0 3 3 3 3 FMRFamide related peptide family UPF0121 PF03661.13 VBB25190.1 - 5.6e-58 196.2 12.1 3e-50 170.9 7.9 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0121) DUF1604 PF07713.13 VBB25192.1 - 3.3e-37 126.2 0.9 9.9e-37 124.6 0.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) RRM_1 PF00076.22 VBB25192.1 - 4.7e-18 64.8 0.1 1.2e-17 63.5 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 VBB25192.1 - 4.8e-08 32.8 1.1 1.6e-07 31.1 1.1 2.0 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.6 VBB25192.1 - 1.3e-05 24.7 0.0 3.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 VBB25192.1 - 0.0003 20.8 0.2 0.00085 19.4 0.2 1.8 1 0 0 1 1 1 1 G-patch domain STI1 PF17830.1 VBB25193.1 - 1.9e-13 50.1 0.4 1.9e-13 50.1 0.4 1.5 2 0 0 2 2 2 1 STI1 domain HipN PF18253.1 VBB25195.1 - 8.2e-18 63.8 0.0 1.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 VBB25195.1 - 1.1e-16 59.9 1.0 2.6e-05 23.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB25195.1 - 1.3e-16 59.2 1.3 2.3e-05 24.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB25195.1 - 1e-08 34.7 0.3 3.4e-05 23.4 0.0 3.6 2 1 2 4 4 4 2 TPR repeat TPR_14 PF13428.6 VBB25195.1 - 4.8e-08 33.2 0.2 0.056 14.3 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB25195.1 - 1.3e-07 31.5 0.6 0.0014 18.9 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB25195.1 - 9.7e-07 28.5 1.1 0.046 14.0 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25195.1 - 3e-05 24.6 0.1 0.0068 17.0 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB25195.1 - 4.6e-05 23.9 0.2 0.00019 21.9 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB25195.1 - 7.9e-05 22.7 0.1 0.0084 16.2 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB25195.1 - 0.00014 22.1 0.6 0.048 14.0 0.4 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB25195.1 - 0.043 13.7 0.2 18 5.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 VBB25195.1 - 0.072 13.8 0.2 19 6.2 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat UCR_6-4kD PF08997.10 VBB25196.1 - 0.019 14.9 0.2 0.037 13.9 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein fn1 PF00039.18 VBB25197.1 - 0.24 11.6 7.9 17 5.7 0.1 3.7 3 0 0 3 3 3 0 Fibronectin type I domain Exo_endo_phos PF03372.23 VBB25198.1 - 7.2e-11 42.1 0.1 1.9e-10 40.7 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HLH PF00010.26 VBB25199.1 - 7.5e-20 70.6 3.0 7.5e-20 70.6 3.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2121 PF09894.9 VBB25199.1 - 0.45 10.0 2.9 0.72 9.4 0.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) Thioredoxin PF00085.20 VBB25200.1 - 0.028 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin CD36 PF01130.21 VBB25201.1 - 5.1e-77 259.4 0.2 1.6e-74 251.1 0.0 2.5 1 1 1 2 2 2 1 CD36 family DUF3784 PF12650.7 VBB25201.1 - 5.4 7.3 9.7 0.5 10.6 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) VPS9 PF02204.18 VBB25202.1 - 1.1e-26 93.0 0.0 4e-26 91.3 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 VBB25202.1 - 3.1e-17 62.6 3.9 1.1e-16 60.8 1.1 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF5601) dCMP_cyt_deam_1 PF00383.23 VBB25202.1 - 8.2e-17 61.0 0.0 2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 VBB25202.1 - 1.8e-12 47.2 0.0 8e-12 45.1 0.0 2.2 1 0 0 1 1 1 1 MafB19-like deaminase zf-A20 PF01754.16 VBB25202.1 - 7.4e-11 41.8 4.0 1.5e-10 40.8 4.0 1.6 1 0 0 1 1 1 1 A20-like zinc finger SNAD4 PF18750.1 VBB25202.1 - 0.0014 18.8 0.0 0.0049 17.0 0.0 2.0 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 CCAP PF11105.8 VBB25202.1 - 0.0014 18.5 0.5 0.054 13.5 0.0 2.7 2 0 0 2 2 2 1 Arthropod cardioacceleratory peptide 2a Bd3614-deam PF14439.6 VBB25202.1 - 0.0014 18.7 0.5 0.0061 16.6 0.5 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase NAD1 PF18778.1 VBB25202.1 - 0.0034 17.5 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 VBB25202.1 - 0.0091 16.1 0.1 0.03 14.4 0.1 1.8 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 VBB25202.1 - 0.052 13.7 0.8 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 HAD_2 PF13419.6 VBB25203.1 - 1.3e-22 80.7 0.1 1.7e-22 80.4 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB25203.1 - 6.4e-11 42.9 0.1 1.9e-09 38.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB25203.1 - 0.022 15.2 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 VBB25203.1 - 0.04 14.0 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Chorismate_bind PF00425.18 VBB25203.1 - 0.12 11.9 0.0 0.52 9.8 0.0 1.8 2 0 0 2 2 2 0 chorismate binding enzyme HAD_2 PF13419.6 VBB25204.1 - 3.8e-20 72.7 0.0 4.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB25204.1 - 2.5e-13 50.8 0.0 6.7e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB25204.1 - 0.0019 18.7 0.0 0.0026 18.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 VBB25204.1 - 0.019 15.1 0.0 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 VBB25204.1 - 0.02 14.9 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Baculo_p74 PF04583.12 VBB25204.1 - 0.11 11.9 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region ABC_membrane PF00664.23 VBB25206.1 - 3.2e-108 361.5 50.3 2.8e-60 204.3 17.4 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 VBB25206.1 - 1.9e-72 242.2 0.2 3.3e-35 121.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter NIF PF03031.18 VBB25206.1 - 7.4e-48 162.3 0.0 2e-47 160.9 0.0 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SMC_N PF02463.19 VBB25206.1 - 8.6e-13 48.2 6.8 3.8e-05 23.2 0.5 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 VBB25206.1 - 2.9e-09 37.6 2.3 0.0024 18.3 0.3 3.3 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 VBB25206.1 - 1.9e-07 31.2 0.0 0.0064 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 VBB25206.1 - 3.2e-07 29.5 0.0 0.0025 16.7 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 VBB25206.1 - 7.5e-07 29.5 1.6 0.056 13.7 0.1 3.8 3 2 0 3 3 2 2 AAA domain AAA_15 PF13175.6 VBB25206.1 - 6.1e-06 26.2 0.0 0.058 13.1 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 VBB25206.1 - 2.4e-05 24.2 0.1 0.28 10.9 0.0 3.6 3 2 0 3 3 3 2 AAA domain DUF815 PF05673.13 VBB25206.1 - 2.4e-05 23.6 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) G-alpha PF00503.20 VBB25206.1 - 2.8e-05 23.5 0.0 0.01 15.0 0.0 2.6 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 VBB25206.1 - 4e-05 23.0 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 VBB25206.1 - 5e-05 22.9 2.3 0.055 13.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 VBB25206.1 - 0.00014 21.9 0.5 1.5 8.9 0.0 3.7 5 0 0 5 5 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 VBB25206.1 - 0.00019 21.6 0.0 0.76 9.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 VBB25206.1 - 0.0002 21.5 0.4 0.76 9.8 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA PF00004.29 VBB25206.1 - 0.00026 21.4 1.8 3 8.3 0.3 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 VBB25206.1 - 0.00052 20.0 0.1 0.29 11.0 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 VBB25206.1 - 0.00058 19.9 0.1 1.5 9.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 VBB25206.1 - 0.00062 19.7 0.1 0.46 10.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 VBB25206.1 - 0.001 18.6 0.1 0.98 8.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 VBB25206.1 - 0.0013 19.3 0.0 0.51 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 VBB25206.1 - 0.0033 17.2 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 VBB25206.1 - 0.0039 16.9 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 VBB25206.1 - 0.0048 17.3 0.0 5.4 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 VBB25206.1 - 0.0059 16.4 0.1 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 VBB25206.1 - 0.0086 16.3 0.1 0.48 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 VBB25206.1 - 0.023 14.3 0.6 4 7.0 0.0 3.0 4 0 0 4 4 2 0 AAA domain SbcCD_C PF13558.6 VBB25206.1 - 0.024 14.9 4.9 5.2 7.4 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 VBB25206.1 - 0.033 13.4 0.4 4 6.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain tRNA_lig_kinase PF08303.11 VBB25206.1 - 0.042 13.9 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain Septin PF00735.18 VBB25206.1 - 0.055 12.7 0.1 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 VBB25206.1 - 0.081 12.1 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain MeaB PF03308.16 VBB25206.1 - 0.092 11.7 0.0 8.8 5.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 VBB25206.1 - 0.099 12.3 0.1 6.1 6.4 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 VBB25206.1 - 0.12 12.1 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FeoB_N PF02421.18 VBB25206.1 - 0.12 11.8 0.0 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 VBB25206.1 - 0.82 10.1 6.7 1.6 9.2 0.3 2.9 3 0 0 3 3 2 0 AAA domain CRCB PF02537.15 VBB25206.1 - 3.4 8.0 12.3 4.9 7.5 0.4 3.6 4 0 0 4 4 2 0 CrcB-like protein, Camphor Resistance (CrcB) PARP_regulatory PF01358.18 VBB25207.1 - 0.11 11.4 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit GATase PF00117.28 VBB25208.1 - 3.3e-37 128.1 0.0 5.7e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 VBB25208.1 - 1e-16 60.8 0.3 9.6e-08 32.0 0.0 3.6 3 1 0 3 3 3 2 GMP synthase C terminal domain NAD_synthase PF02540.17 VBB25208.1 - 1.9e-10 40.3 0.0 2.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 VBB25208.1 - 2.5e-10 40.5 0.0 6.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 VBB25208.1 - 0.00014 21.5 0.0 0.00094 18.7 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 VBB25208.1 - 0.00037 20.1 0.1 0.00077 19.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 VBB25208.1 - 0.0016 17.3 0.1 0.012 14.4 0.1 2.0 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 VBB25208.1 - 0.0035 17.1 0.3 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.21 VBB25208.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Med8 PF10232.9 VBB25209.1 - 3.8e-21 75.8 7.2 1.7e-20 73.6 7.2 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PPP1R35_C PF15503.6 VBB25210.1 - 4.6e-06 26.5 0.8 5.9e-06 26.1 0.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Med26 PF08711.11 VBB25211.1 - 2.3e-05 24.3 0.2 4.2e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain IFT43 PF15305.6 VBB25213.1 - 1.3e-18 67.4 0.1 2.2e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Intraflagellar transport protein 43 V_ATPase_I PF01496.19 VBB25214.1 - 3.5e-244 812.5 22.6 4.8e-171 570.6 2.0 3.0 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 VBB25214.1 - 0.015 15.5 0.4 0.034 14.4 0.4 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain L27_N PF09060.10 VBB25214.1 - 0.72 10.0 2.7 1.8 8.7 2.7 1.7 1 0 0 1 1 1 0 L27_N HAUS4 PF14735.6 VBB25214.1 - 0.86 9.3 5.7 5.3 6.7 0.2 3.0 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 4 PCRF PF03462.18 VBB25214.1 - 1.5 8.6 4.6 2.4 8.0 0.9 2.2 2 0 0 2 2 2 0 PCRF domain Motile_Sperm PF00635.26 VBB25215.1 - 6.3e-20 71.0 0.0 7.8e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Dala_Dala_lig_C PF07478.13 VBB25217.1 - 0.015 14.9 0.5 0.02 14.4 0.1 1.4 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Y_phosphatase PF00102.27 VBB25219.1 - 3.4e-65 219.9 1.5 4.6e-65 219.5 1.5 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB25219.1 - 7.7e-07 29.3 0.0 2.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 VBB25219.1 - 0.00042 20.1 0.4 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB25219.1 - 0.0011 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.32 VBB25220.1 - 6.7e-11 42.6 0.9 1e-05 26.2 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB25220.1 - 0.014 15.6 0.0 9.4 6.6 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 VBB25221.1 - 2.3e-28 98.2 12.6 5.3e-12 46.0 0.0 10.4 6 3 5 11 11 11 6 HEAT-like repeat HEAT PF02985.22 VBB25221.1 - 3.1e-15 55.0 19.4 0.053 13.8 0.0 11.1 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.7 VBB25221.1 - 3.4e-14 53.2 0.0 0.01 16.4 0.0 6.9 5 2 2 7 7 7 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 VBB25221.1 - 2e-12 46.9 0.9 5.8e-12 45.4 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 VBB25221.1 - 3.4e-11 42.9 10.5 0.00061 19.0 0.0 6.0 5 1 2 7 7 7 4 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 VBB25221.1 - 5.1e-11 42.9 0.5 0.00072 19.6 0.0 4.4 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 VBB25221.1 - 3.7e-10 40.0 0.7 0.099 13.0 0.0 6.5 4 2 3 7 7 7 3 HEAT repeats Arm PF00514.23 VBB25221.1 - 5.6e-10 38.9 11.5 0.33 11.1 0.0 8.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 VBB25221.1 - 1.7e-06 26.9 1.6 0.042 12.4 0.1 3.0 2 1 0 2 2 2 2 Adaptin N terminal region DUF3385 PF11865.8 VBB25221.1 - 6.8e-06 26.1 0.0 0.1 12.5 0.0 4.9 4 2 2 6 6 6 1 Domain of unknown function (DUF3385) UME PF08064.13 VBB25221.1 - 0.0013 18.6 0.2 10 6.1 0.0 5.2 3 2 1 4 4 4 1 UME (NUC010) domain CLASP_N PF12348.8 VBB25221.1 - 0.019 14.6 0.4 0.98 8.9 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal Proteasom_PSMB PF10508.9 VBB25221.1 - 0.051 12.1 0.1 0.29 9.6 0.0 2.2 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.12 VBB25221.1 - 0.052 13.3 0.2 12 5.6 0.0 3.9 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 VBB25221.1 - 0.47 10.5 3.9 0.98 9.5 0.0 3.5 5 0 0 5 5 5 0 Exportin 1-like protein Tti2 PF10521.9 VBB25221.1 - 0.5 9.8 3.1 21 4.5 0.0 3.8 2 2 1 3 3 3 0 Tti2 family Neur_chan_LBD PF02931.23 VBB25222.1 - 8.7e-39 133.2 1.1 5e-22 78.4 0.1 2.4 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB25222.1 - 1.2e-38 133.6 14.9 7.1e-20 72.1 6.1 2.6 2 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF5357 PF17310.2 VBB25222.1 - 0.032 12.8 3.1 0.14 10.7 3.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5357) DUF4327 PF14217.6 VBB25222.1 - 0.042 14.0 2.0 0.19 11.9 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4327) Peptidase_U4 PF03419.13 VBB25222.1 - 0.33 10.2 9.3 0.77 9.0 3.0 2.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF3147 PF11345.8 VBB25222.1 - 0.58 10.6 5.9 6.7 7.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) MotB_plug PF13677.6 VBB25225.1 - 0.17 11.5 6.4 1.5 8.4 0.0 2.8 3 0 0 3 3 3 0 Membrane MotB of proton-channel complex MotA/MotB PUF PF00806.19 VBB25226.1 - 3.4e-40 133.5 12.2 2.7e-06 26.7 0.1 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Imm30 PF15565.6 VBB25226.1 - 0.0038 17.3 0.1 0.012 15.7 0.1 1.9 1 0 0 1 1 1 1 Immunity protein 30 RICTOR_M PF14666.6 VBB25226.1 - 0.052 13.3 2.4 8.7 6.2 0.0 3.6 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain CPL PF08144.11 VBB25226.1 - 0.18 12.1 3.1 0.46 10.8 0.8 2.8 2 2 1 3 3 3 0 CPL (NUC119) domain Nucleotid_trans PF03407.16 VBB25227.1 - 8.5e-31 107.6 0.0 1.3e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Cys_rich_VLP PF14194.6 VBB25227.1 - 0.11 12.6 0.8 3.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich VLP C2 PF00168.30 VBB25228.1 - 4.2e-33 113.7 0.0 4e-15 56.0 0.0 3.4 3 0 0 3 3 3 2 C2 domain PDZ_6 PF17820.1 VBB25228.1 - 2.4e-10 40.1 0.1 5.5e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB25228.1 - 8.9e-10 38.8 0.0 2.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB25228.1 - 0.0042 17.4 0.8 0.01 16.1 0.1 2.0 2 0 0 2 2 2 1 PDZ domain Sas10_Utp3 PF04000.15 VBB25229.1 - 1.2e-05 25.8 0.2 3.4e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Sec16_C PF12931.7 VBB25230.1 - 3.4e-17 63.1 0.0 1.3e-16 61.1 0.0 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 VBB25230.1 - 1e-05 26.1 1.7 1.5e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region CLTH PF10607.9 VBB25230.1 - 0.063 13.2 0.1 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain RRM_1 PF00076.22 VBB25231.1 - 6.9e-28 96.3 0.0 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB25231.1 - 0.00012 21.7 0.0 0.26 10.9 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB25231.1 - 0.0047 16.8 0.1 0.88 9.5 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif ketoacyl-synt PF00109.26 VBB25232.1 - 3.2e-155 515.1 1.5 1.1e-56 192.3 0.2 3.7 3 0 0 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 VBB25232.1 - 6e-89 296.7 0.1 3.2e-43 147.7 0.0 4.1 4 0 0 4 4 4 3 KR domain Ketoacyl-synt_C PF02801.22 VBB25232.1 - 4.9e-84 278.1 5.8 2.4e-29 101.7 0.2 3.6 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 VBB25232.1 - 2.9e-55 184.5 3.2 1.3e-11 44.6 0.0 5.7 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding PF00501.28 VBB25232.1 - 3.3e-49 167.6 0.0 5.8e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.21 VBB25232.1 - 9.9e-47 160.0 0.0 1.6e-25 90.3 0.0 2.6 2 0 0 2 2 2 2 Acyl transferase domain Condensation PF00668.20 VBB25232.1 - 9e-43 146.6 7.1 1.7e-42 145.7 7.1 1.4 1 0 0 1 1 1 1 Condensation domain KAsynt_C_assoc PF16197.5 VBB25232.1 - 3.9e-30 104.6 0.2 8.1e-10 39.1 0.0 3.8 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 VBB25232.1 - 1.1e-19 70.8 0.0 2.1e-09 37.1 0.0 4.2 4 0 0 4 4 4 2 Polyketide synthase dehydratase adh_short PF00106.25 VBB25232.1 - 2.3e-17 63.1 1.6 9.1e-06 25.3 0.1 3.7 3 0 0 3 3 3 3 short chain dehydrogenase Thioesterase PF00975.20 VBB25232.1 - 1.8e-11 44.6 0.0 6.2e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain adh_short_C2 PF13561.6 VBB25232.1 - 1.5e-10 41.0 0.7 0.00042 20.0 0.0 3.8 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 VBB25232.1 - 1e-08 34.9 0.4 0.0051 16.3 0.0 4.2 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 VBB25232.1 - 6.8e-06 25.6 5.2 0.05 13.0 0.1 4.3 5 0 0 5 5 5 2 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 VBB25232.1 - 3.4e-05 24.1 0.0 0.0025 18.1 0.0 3.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AMP-binding_C PF13193.6 VBB25232.1 - 0.0027 18.6 0.0 0.0064 17.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 VBB25232.1 - 0.0033 16.9 1.8 0.011 15.2 0.0 2.6 3 0 0 3 3 2 1 GDP-mannose 4,6 dehydratase PGAP1 PF07819.13 VBB25232.1 - 0.0095 15.7 0.4 0.035 13.8 0.0 2.2 2 0 0 2 2 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 VBB25232.1 - 0.017 14.9 0.0 0.27 11.0 0.0 3.0 3 0 0 3 3 2 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 VBB25232.1 - 0.027 14.3 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 1 0 Palmitoyl protein thioesterase DOPA_dioxygen PF08883.11 VBB25232.1 - 0.035 14.3 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family ACP_syn_III PF08545.10 VBB25232.1 - 0.052 13.4 9.1 0.24 11.3 0.3 4.3 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_1 PF00561.20 VBB25232.1 - 0.13 11.8 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Phage_holin_3_1 PF05106.12 VBB25232.1 - 0.15 12.5 0.2 0.7 10.4 0.0 2.3 2 0 0 2 2 1 0 Phage holin family (Lysis protein S) COesterase PF00135.28 VBB25233.1 - 7.1e-81 272.6 0.0 1.2e-80 271.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB25233.1 - 0.00091 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0184 PF03670.13 VBB25234.1 - 0.0039 17.5 7.1 0.0039 17.5 7.1 2.7 2 2 1 3 3 3 1 Uncharacterised protein family (UPF0184) PKK PF12474.8 VBB25234.1 - 0.0091 16.1 9.8 0.0091 16.1 9.8 2.2 2 1 0 2 2 2 1 Polo kinase kinase DUF1366 PF07104.11 VBB25234.1 - 0.017 14.8 0.9 0.04 13.6 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) LSM14 PF12701.7 VBB25234.1 - 0.05 13.7 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Scd6-like Sm domain XhlA PF10779.9 VBB25234.1 - 0.38 11.0 2.5 1.2 9.3 2.5 2.0 1 0 0 1 1 1 0 Haemolysin XhlA Muted PF14942.6 VBB25234.1 - 4.5 7.6 18.7 1.2 9.4 14.3 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein LMBR1 PF04791.16 VBB25234.1 - 6.9 5.5 17.0 12 4.7 17.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 VBB25234.1 - 8.4 5.6 11.4 15 4.8 11.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Radical_SAM_C PF16199.5 VBB25235.1 - 2.3e-30 104.4 0.1 6.4e-30 103.0 0.1 1.8 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 VBB25235.1 - 1.7e-21 77.3 0.2 6.1e-20 72.3 0.1 2.9 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 VBB25235.1 - 2e-10 40.9 0.1 4.2e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB25235.1 - 1e-05 25.5 0.1 3.4e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 VBB25235.1 - 2.7e-05 23.9 0.2 6.5e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 VBB25235.1 - 4.8e-05 23.6 0.1 0.00015 22.0 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type NTP_transf_2 PF01909.23 VBB25235.1 - 0.00039 20.7 0.0 0.002 18.4 0.0 2.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain RL PF17797.1 VBB25235.1 - 0.0062 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RL domain Acetyltransf_7 PF13508.7 VBB25235.1 - 0.0071 16.8 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cmc1 PF08583.10 VBB25236.1 - 8.8e-07 28.9 1.6 1.3e-06 28.3 1.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 VBB25236.1 - 0.011 15.9 1.7 0.024 14.8 1.7 1.6 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 VBB25236.1 - 0.84 9.7 4.8 1 9.4 0.2 2.8 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF21 PF01595.20 VBB25237.1 - 5.7e-33 114.1 0.7 9.9e-33 113.3 0.7 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 VBB25237.1 - 2.3e-06 27.9 2.1 0.0023 18.3 0.1 2.8 2 0 0 2 2 2 2 CBS domain Cupin_2 PF07883.11 VBB25237.1 - 0.14 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain FMO-like PF00743.19 VBB25238.1 - 7e-175 582.4 0.0 8.6e-175 582.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 VBB25238.1 - 2.4e-20 73.0 0.0 1.9e-16 60.2 0.0 2.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 VBB25238.1 - 1.7e-09 37.3 0.0 2.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 VBB25238.1 - 6.3e-08 32.1 0.1 1.1e-05 24.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 VBB25238.1 - 6.7e-08 32.6 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 VBB25238.1 - 0.00013 21.3 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 VBB25238.1 - 0.00029 20.8 0.1 0.0016 18.5 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 VBB25238.1 - 0.00032 19.9 0.1 0.00053 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 VBB25238.1 - 0.0013 17.6 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 VBB25238.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 VBB25238.1 - 0.0037 16.9 0.1 0.48 10.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 VBB25238.1 - 0.03 13.6 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 VBB25238.1 - 0.12 13.0 0.4 13 6.5 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 VBB25238.1 - 0.13 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain SNF PF00209.18 VBB25241.1 - 6.7e-32 110.9 31.3 6e-30 104.4 17.6 3.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family GET2 PF08690.10 VBB25241.1 - 0.25 11.0 5.8 0.032 13.9 1.1 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 Musclin PF11037.8 VBB25241.1 - 1.9 8.5 5.7 3.4 7.6 5.7 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Peptidase_S49_N PF08496.10 VBB25241.1 - 7 6.7 9.9 20 5.2 9.9 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_S19e PF01090.19 VBB25243.1 - 1e-57 193.7 0.1 1.1e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e IF3_C PF00707.22 VBB25243.1 - 0.0084 16.0 0.5 1.6 8.8 0.2 2.7 2 1 1 3 3 3 2 Translation initiation factor IF-3, C-terminal domain GntR PF00392.21 VBB25243.1 - 0.039 13.6 0.0 0.094 12.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Proteasome PF00227.26 VBB25244.1 - 3.2e-58 196.4 0.0 5e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit YchF-GTPase_C PF06071.13 VBB25244.1 - 3.7e-30 104.0 0.6 1.2e-29 102.3 0.2 2.2 2 0 0 2 2 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 VBB25244.1 - 3.2e-21 75.5 0.0 1.2e-20 73.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Proteasome_A_N PF10584.9 VBB25244.1 - 9.6e-14 50.7 0.2 1.8e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LSM PF01423.22 VBB25244.1 - 7.6e-10 38.3 0.0 2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 LSM domain zf-C2H2 PF00096.26 VBB25244.1 - 3.9e-08 33.3 36.8 0.0004 20.7 2.3 4.0 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB25244.1 - 1.8e-07 31.3 10.7 8.9e-06 25.9 2.9 5.2 6 0 0 6 6 5 2 Zinc-finger double domain FeoB_N PF02421.18 VBB25244.1 - 1.9e-07 30.7 0.1 1.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B zf-C2H2_4 PF13894.6 VBB25244.1 - 0.00016 22.2 31.4 0.017 15.9 3.6 4.5 4 0 0 4 4 3 3 C2H2-type zinc finger TGS PF02824.21 VBB25244.1 - 0.014 15.4 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 TGS domain MeaB PF03308.16 VBB25244.1 - 0.031 13.3 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-BED PF02892.15 VBB25244.1 - 0.43 10.6 12.8 2.8 8.0 1.2 2.8 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_8 PF15909.5 VBB25244.1 - 0.46 10.8 5.7 1.4 9.3 5.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 VBB25244.1 - 0.74 10.2 20.9 0.18 12.1 0.3 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Nudix_N_2 PF14803.6 VBB25244.1 - 4.5 7.3 6.1 5.9 6.9 0.7 2.9 2 0 0 2 2 2 0 Nudix N-terminal DUF1576 PF07613.11 VBB25245.1 - 0.051 13.1 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) MIG-14_Wnt-bd PF06664.12 VBB25245.1 - 0.073 12.3 0.1 0.095 11.9 0.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF2407_C PF13373.6 VBB25245.1 - 0.12 12.5 1.7 4.8 7.4 0.0 2.2 1 1 1 2 2 2 0 DUF2407 C-terminal domain Romo1 PF10247.9 VBB25245.1 - 0.13 12.6 4.7 2.2 8.7 0.5 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 PhoR PF11808.8 VBB25245.1 - 0.8 10.2 2.5 2.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR HMG_box PF00505.19 VBB25246.1 - 7.4e-26 90.4 1.3 1.2e-25 89.7 1.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB25246.1 - 4.4e-09 36.8 0.9 8.1e-09 36.0 0.9 1.4 1 0 0 1 1 1 1 HMG-box domain DUF2624 PF11116.8 VBB25246.1 - 0.056 14.3 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Pkinase PF00069.25 VBB25247.1 - 2e-18 66.7 1.2 3.9e-18 65.8 0.4 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25247.1 - 4.5e-18 65.5 0.3 8.9e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ferrochelatase PF00762.19 VBB25247.1 - 9.8e-12 44.6 0.7 1.1e-10 41.1 0.7 2.4 1 1 0 1 1 1 1 Ferrochelatase Pkinase PF00069.25 VBB25248.1 - 0.00096 18.6 0.1 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain OSR1_C PF12202.8 VBB25248.1 - 0.054 13.7 0.4 0.45 10.8 0.1 2.3 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain Guanylate_kin PF00625.21 VBB25249.1 - 2.2e-41 141.5 0.0 6.9e-41 139.9 0.0 1.8 2 1 0 2 2 2 1 Guanylate kinase SH3_2 PF07653.17 VBB25249.1 - 2.8e-05 23.7 0.0 0.00022 20.8 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain PDZ_6 PF17820.1 VBB25249.1 - 0.00056 19.7 0.5 0.0085 15.9 0.1 2.9 2 1 1 3 3 3 1 PDZ domain SH3_1 PF00018.28 VBB25249.1 - 0.0013 18.3 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 VBB25249.1 - 0.006 16.9 0.6 0.013 15.8 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB25249.1 - 0.0069 16.7 0.1 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain FYVE PF01363.21 VBB25250.1 - 4.1e-20 71.7 10.5 9.8e-20 70.5 10.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 VBB25250.1 - 0.17 12.1 7.6 0.49 10.6 7.6 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 VBB25250.1 - 0.64 10.2 10.4 0.45 10.8 7.6 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zf_C2HC_14 PF18574.1 VBB25250.1 - 1.5 8.7 6.4 3.7 7.4 6.4 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain NAPRTase_C PF17956.1 VBB25251.1 - 0.03 14.8 1.0 2.3 8.7 0.1 3.2 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain Virul_Fac PF10139.9 VBB25251.1 - 0.054 11.7 0.1 0.068 11.4 0.1 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor FANCI_S1-cap PF14674.6 VBB25251.1 - 0.13 12.3 1.1 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap GTP_EFTU PF00009.27 VBB25252.1 - 1.6e-51 174.6 0.2 3.4e-51 173.6 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 VBB25252.1 - 1.2e-27 96.1 0.6 2.2e-27 95.3 0.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 VBB25252.1 - 7.7e-11 41.9 0.0 2.7e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 VBB25252.1 - 4.4e-06 26.7 0.0 1.9e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.22 VBB25252.1 - 8.8e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 VBB25252.1 - 9.9e-06 25.9 0.1 2.6e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 VBB25252.1 - 2.3e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 VBB25252.1 - 0.00042 20.4 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 VBB25252.1 - 0.0099 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SBDS_C PF09377.10 VBB25252.1 - 0.014 15.4 0.1 0.042 13.9 0.1 1.8 1 0 0 1 1 1 0 SBDS protein C-terminal domain SRPRB PF09439.10 VBB25252.1 - 0.016 14.7 0.0 0.048 13.1 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 VBB25252.1 - 0.049 13.2 0.0 0.23 11.0 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 VBB25252.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Tetraspanin PF00335.20 VBB25253.1 - 1.4e-21 77.3 4.2 1.7e-21 77.0 4.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4042 PF13251.6 VBB25253.1 - 0.1 12.3 0.5 1.7 8.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) Sigma_reg_N PF13800.6 VBB25253.1 - 0.35 11.2 3.3 12 6.2 0.4 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-C2H2_4 PF13894.6 VBB25254.1 - 1.4e-22 78.4 96.0 0.02 15.7 0.2 15.6 15 0 0 15 15 15 10 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB25254.1 - 1.6e-16 59.7 96.6 0.0034 17.8 0.5 14.5 14 0 0 14 14 14 9 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 VBB25254.1 - 0.0002 21.6 79.9 0.12 12.6 0.1 14.1 14 0 0 14 14 13 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB25254.1 - 0.00063 19.7 0.8 0.00063 19.7 0.8 10.7 11 0 0 11 11 11 3 C2H2-type zinc finger zf-met PF12874.7 VBB25254.1 - 0.0012 19.1 76.2 0.39 11.2 0.1 13.5 14 0 0 14 14 13 6 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 VBB25254.1 - 0.0044 17.7 73.7 0.11 13.1 3.3 9.0 4 3 6 10 10 10 6 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 VBB25254.1 - 0.037 14.5 1.2 0.037 14.5 1.2 12.6 14 0 0 14 14 13 0 Zinc-finger double domain Ribosomal_L34e PF01199.18 VBB25254.1 - 0.15 12.4 6.8 2.2 8.7 0.1 4.3 3 1 0 3 3 3 0 Ribosomal protein L34e C1_2 PF03107.16 VBB25254.1 - 0.5 10.7 0.1 0.5 10.7 0.1 12.0 8 4 2 10 10 9 0 C1 domain BolA PF01722.18 VBB25254.1 - 1.9 8.8 8.6 37 4.7 0.0 4.3 3 1 0 3 3 3 0 BolA-like protein Ribosomal_L37ae PF01780.19 VBB25254.1 - 2.7 8.1 10.8 27 4.9 0.1 5.2 4 1 0 4 4 4 0 Ribosomal L37ae protein family Androgen_recep PF02166.16 VBB25254.1 - 9.2 5.0 6.5 1.4 7.7 1.9 1.8 2 0 0 2 2 2 0 Androgen receptor BAR PF03114.18 VBB25255.1 - 3.1e-61 207.1 10.5 3.8e-61 206.8 10.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 VBB25255.1 - 4e-15 55.1 0.1 7.1e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB25255.1 - 4.4e-15 55.3 0.1 7e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 VBB25255.1 - 2.9e-14 52.9 5.7 2.7e-12 46.5 4.0 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.17 VBB25255.1 - 1.9e-12 46.6 0.0 3.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 VBB25255.1 - 0.00041 20.1 4.2 0.0017 18.1 4.2 1.8 1 1 0 1 1 1 1 BAR domain of APPL family PhnG PF06754.12 VBB25255.1 - 0.36 10.8 3.0 0.31 11.0 0.8 2.0 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG DUF3461 PF11944.8 VBB25255.1 - 1.9 8.6 7.9 9.4 6.4 7.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) Vac14_Fig4_bd PF11916.8 VBB25256.1 - 1.3e-59 200.9 7.8 1.3e-59 200.9 7.8 2.6 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 VBB25256.1 - 2.1e-48 162.9 0.1 5.5e-41 139.1 0.0 4.7 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 VBB25256.1 - 3.2e-11 42.5 8.5 4.9e-05 23.2 0.0 7.0 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 VBB25256.1 - 3.4e-09 37.0 4.0 0.0046 17.4 0.0 5.4 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.8 VBB25256.1 - 4.4e-09 36.2 0.2 0.0072 15.9 0.0 4.3 1 1 3 4 4 4 3 CLASP N terminal HEAT_2 PF13646.6 VBB25256.1 - 6.6e-09 36.0 3.2 0.02 15.3 0.0 4.9 5 0 0 5 5 5 3 HEAT repeats DUF3437 PF11919.8 VBB25256.1 - 0.0013 18.6 0.1 0.028 14.3 0.0 3.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Arm PF00514.23 VBB25256.1 - 0.28 11.3 1.8 17 5.6 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 VBB25257.1 - 1.3e-09 38.1 24.8 0.00033 21.0 2.4 5.0 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB25257.1 - 2.4e-06 27.1 1.4 2.4e-06 27.1 1.4 3.8 3 1 1 4 4 4 1 Leucine-rich repeat LRR_8 PF13855.6 VBB25257.1 - 4.6e-06 26.3 19.7 0.0031 17.2 6.4 4.0 1 1 1 3 3 3 3 Leucine rich repeat IQ PF00612.27 VBB25257.1 - 0.00096 18.7 2.5 0.0029 17.2 1.5 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif LRR_6 PF13516.6 VBB25257.1 - 0.0013 18.6 15.4 1.5 9.0 0.8 4.7 4 0 0 4 4 4 3 Leucine Rich repeat TolA_bind_tri PF16331.5 VBB25257.1 - 0.12 12.4 8.7 0.64 10.1 8.7 2.3 1 1 0 1 1 1 0 TolA binding protein trimerisation LRR_1 PF00560.33 VBB25257.1 - 0.24 12.1 18.9 2.1 9.2 0.6 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat RecG_N PF17190.4 VBB25257.1 - 0.26 12.1 5.4 1.4 9.7 2.8 2.8 2 0 0 2 2 2 0 RecG N-terminal helical domain zf-C3HC PF07967.13 VBB25257.1 - 1.4 9.0 6.3 0.6 10.2 3.1 2.0 2 0 0 2 2 2 0 C3HC zinc finger-like Zw10 PF06248.13 VBB25258.1 - 0.012 14.2 0.3 0.021 13.4 0.3 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 MurB_C PF02873.16 VBB25258.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Baculo_p24 PF05073.12 VBB25258.1 - 1.2 8.9 4.9 0.24 11.2 0.3 2.1 3 0 0 3 3 3 0 Baculovirus P24 capsid protein RAI1 PF08652.11 VBB25259.1 - 3.4e-18 65.6 0.2 1.6e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Vps5 PF09325.10 VBB25260.1 - 2.8e-63 213.6 15.3 3.8e-63 213.2 15.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 VBB25260.1 - 4.8e-22 78.1 1.7 3.1e-21 75.5 0.1 2.4 3 0 0 3 3 3 1 PX domain BAR_3_WASP_bdg PF10456.9 VBB25260.1 - 0.0005 19.6 3.6 0.076 12.5 2.6 3.0 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein T3SSipB PF16535.5 VBB25260.1 - 0.014 15.8 1.7 0.18 12.3 0.6 2.5 2 0 0 2 2 2 0 Type III cell invasion protein SipB BLOC1_2 PF10046.9 VBB25260.1 - 0.065 13.5 5.0 1.2 9.5 0.0 3.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 VBB25260.1 - 0.11 12.8 0.3 19 5.6 0.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 VBB25260.1 - 0.14 12.2 7.0 2.8 8.0 0.3 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PilO PF04350.13 VBB25260.1 - 0.33 11.1 3.8 1.1 9.4 0.2 2.7 2 0 0 2 2 2 0 Pilus assembly protein, PilO Occludin_ELL PF07303.13 VBB25260.1 - 0.35 11.6 8.0 3 8.6 3.0 3.3 2 1 0 2 2 2 0 Occludin homology domain FlaC_arch PF05377.11 VBB25260.1 - 0.37 11.2 3.0 9.2 6.7 0.2 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Uds1 PF15456.6 VBB25260.1 - 0.39 10.9 5.9 0.23 11.6 0.6 2.6 2 1 0 2 2 2 0 Up-regulated During Septation HBM PF16591.5 VBB25260.1 - 0.71 9.2 8.8 0.43 9.9 0.5 2.6 1 1 1 2 2 2 0 Helical bimodular sensor domain Sec20 PF03908.13 VBB25260.1 - 0.96 9.4 7.6 0.75 9.8 1.0 3.1 2 1 0 2 2 2 0 Sec20 V-SNARE PF05008.15 VBB25260.1 - 1.1 9.7 12.1 1.3 9.5 5.5 3.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MatP_C PF17414.2 VBB25260.1 - 2.3 8.5 7.4 27 5.1 0.1 3.9 4 0 0 4 4 4 0 MatP C-terminal ribbon-helix-helix domain CLZ PF16526.5 VBB25260.1 - 7.3 7.0 7.9 1.5 9.2 0.2 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Glyco_hydro_47 PF01532.20 VBB25261.1 - 4.3e-132 441.3 0.4 5.3e-132 441.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 VBB25261.1 - 0.02 14.4 0.7 3 7.3 0.0 2.7 2 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus NIF PF03031.18 VBB25262.1 - 1.8e-53 180.5 0.7 3.7e-53 179.5 0.5 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Cut8 PF08559.10 VBB25262.1 - 0.058 13.0 0.3 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein UPF0113 PF03657.13 VBB25263.1 - 7.1e-26 90.3 0.0 2.2e-25 88.7 0.0 1.9 2 0 0 2 2 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 VBB25263.1 - 2.5e-18 66.4 4.6 1.8e-17 63.6 0.1 4.0 4 1 0 4 4 3 1 UPF0113 Pre-PUA domain AAA_22 PF13401.6 VBB25263.1 - 2.1e-13 50.7 0.1 1.1e-11 45.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB25263.1 - 8.4e-12 45.8 0.1 4.6e-11 43.4 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 VBB25263.1 - 4.4e-09 36.9 0.3 2.8e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 VBB25263.1 - 2.4e-05 24.2 1.7 4.4e-05 23.4 0.6 2.0 2 0 0 2 2 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 VBB25263.1 - 3.6e-05 23.8 0.3 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 AAA lid domain ATPase_2 PF01637.18 VBB25263.1 - 5.6e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 VBB25263.1 - 9.9e-05 22.4 0.0 0.00051 20.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 VBB25263.1 - 0.00023 21.5 0.0 0.0029 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 VBB25263.1 - 0.0003 20.8 0.0 0.00081 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 VBB25263.1 - 0.00034 19.9 0.0 0.00067 18.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TniB PF05621.11 VBB25263.1 - 0.00037 19.9 0.1 0.00088 18.7 0.0 1.6 2 0 0 2 2 1 1 Bacterial TniB protein DUF2075 PF09848.9 VBB25263.1 - 0.00038 19.8 0.0 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 VBB25263.1 - 0.00052 19.8 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 VBB25263.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Zot PF05707.12 VBB25263.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) T2SSE PF00437.20 VBB25263.1 - 0.0033 16.5 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.6 VBB25263.1 - 0.0042 16.9 0.1 0.0042 16.9 0.1 2.6 2 2 2 4 4 4 1 AAA domain AAA_24 PF13479.6 VBB25263.1 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 VBB25263.1 - 0.0051 16.0 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA_2 PF07724.14 VBB25263.1 - 0.0068 16.5 0.1 0.035 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) UvrD-helicase PF00580.21 VBB25263.1 - 0.009 15.6 0.2 0.078 12.5 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_18 PF13238.6 VBB25263.1 - 0.0095 16.5 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 VBB25263.1 - 0.01 15.6 0.4 1.9 8.2 0.1 2.7 2 1 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 VBB25263.1 - 0.032 14.6 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 VBB25263.1 - 0.042 13.2 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 VBB25263.1 - 0.057 12.9 0.1 0.66 9.4 0.0 2.4 1 1 1 2 2 2 0 PhoH-like protein PUA PF01472.20 VBB25263.1 - 0.057 13.4 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 1 0 PUA domain AAA_10 PF12846.7 VBB25263.1 - 0.061 12.2 0.1 0.41 9.5 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_33 PF13671.6 VBB25263.1 - 0.074 13.2 0.0 0.48 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 VBB25263.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 VBB25263.1 - 0.077 12.7 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Glyco_hydro_65m PF03632.15 VBB25263.1 - 0.079 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain NTPase_1 PF03266.15 VBB25263.1 - 0.11 12.4 0.2 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.11 VBB25263.1 - 0.17 11.8 0.1 0.85 9.5 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SET PF00856.28 VBB25264.1 - 1.9e-13 51.2 5.6 3.6e-13 50.2 0.0 3.9 4 0 0 4 4 4 1 SET domain SRI PF08236.11 VBB25264.1 - 1.2e-10 41.4 0.2 5.2e-10 39.4 0.2 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 VBB25264.1 - 5.1e-08 32.8 4.2 5.1e-08 32.8 4.2 2.5 3 0 0 3 3 3 1 AWS domain WW PF00397.26 VBB25264.1 - 6.9e-08 32.4 0.5 1.7e-07 31.2 0.5 1.7 1 0 0 1 1 1 1 WW domain ERCC4 PF02732.15 VBB25264.1 - 7.4e-08 32.8 0.2 2.3e-07 31.2 0.2 2.0 1 0 0 1 1 1 1 ERCC4 domain COG5 PF10392.9 VBB25265.1 - 5e-09 36.4 1.2 5e-09 36.4 1.2 4.1 2 1 3 5 5 5 1 Golgi transport complex subunit 5 TFIIIC_sub6 PF10419.9 VBB25265.1 - 2e-08 34.0 0.0 6.8e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain ApoLp-III PF07464.11 VBB25265.1 - 0.0032 17.6 0.2 0.0032 17.6 0.2 3.1 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) RRF PF01765.19 VBB25265.1 - 0.038 13.9 5.1 0.062 13.2 0.0 3.0 3 0 0 3 3 3 0 Ribosome recycling factor SlyX PF04102.12 VBB25265.1 - 0.1 13.2 1.0 0.52 11.0 0.4 2.6 2 0 0 2 2 2 0 SlyX GTP_EFTU PF00009.27 VBB25266.1 - 5.7e-40 136.9 0.1 1e-39 136.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pkinase PF00069.25 VBB25266.1 - 3.2e-26 92.3 0.0 5.8e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25266.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_EFTU_D2 PF03144.25 VBB25266.1 - 2.7e-11 43.7 2.9 6.7e-11 42.4 2.9 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Pkinase_fungal PF17667.1 VBB25266.1 - 4.9e-06 25.6 1.3 1.2e-05 24.3 0.6 1.8 2 0 0 2 2 2 1 Fungal protein kinase cobW PF02492.19 VBB25266.1 - 0.0035 17.0 0.1 0.0068 16.0 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 VBB25266.1 - 0.055 13.4 0.2 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase APH PF01636.23 VBB25266.1 - 0.2 11.6 0.1 26 4.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.15 VBB25267.1 - 1.6e-19 69.3 1.8 2e-19 69.0 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 VBB25267.1 - 0.0047 16.6 1.9 0.018 14.8 1.9 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Chromosome_seg PF13889.6 VBB25268.1 - 1.6e-13 50.6 0.6 3.7e-13 49.4 0.2 2.0 2 0 0 2 2 2 1 Chromosome segregation during meiosis DUF4210 PF13915.6 VBB25268.1 - 2.2e-07 31.3 0.0 4.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) RIO1 PF01163.22 VBB25269.1 - 3.6e-72 241.9 0.0 3.6e-72 241.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 VBB25269.1 - 0.0011 18.4 0.1 0.018 14.4 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB25269.1 - 0.0011 17.8 0.1 0.0011 17.8 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 VBB25269.1 - 0.013 15.4 0.1 1.2 9.0 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family CDC45 PF02724.14 VBB25269.1 - 9.5 4.4 15.8 7.5 4.7 9.5 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF3034 PF11231.8 VBB25270.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) XPC-binding PF09280.11 VBB25270.1 - 0.16 11.8 1.5 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 XPC-binding domain Abhydrolase_1 PF00561.20 VBB25271.1 - 2.5e-19 69.9 0.0 1.5e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 VBB25271.1 - 2.6e-13 51.1 0.0 9.7e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 VBB25271.1 - 2e-10 40.4 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 VBB25271.1 - 5.7e-09 36.0 0.0 1.9e-07 31.0 0.0 2.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 VBB25271.1 - 8.4e-05 22.2 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 VBB25271.1 - 0.0001 22.5 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 VBB25271.1 - 0.00064 19.6 0.0 0.00085 19.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 VBB25271.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 VBB25271.1 - 0.0044 16.1 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF2974 PF11187.8 VBB25271.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_2 PF01674.18 VBB25271.1 - 0.058 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Lipase_3 PF01764.25 VBB25271.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) RRM_1 PF00076.22 VBB25272.1 - 4.6e-13 48.8 0.0 9.1e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 VBB25272.1 - 3.7e-08 32.9 3.3 9.9e-08 31.6 2.1 2.5 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.6 VBB25272.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RUN PF02759.19 VBB25273.1 - 0.02 14.8 0.3 0.074 13.0 0.3 1.9 1 1 0 1 1 1 0 RUN domain Histone PF00125.24 VBB25274.1 - 2.9e-36 124.7 4.0 3.7e-36 124.4 4.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 VBB25274.1 - 0.00059 19.9 0.6 0.0015 18.7 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 VBB25274.1 - 0.027 14.9 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein RNA_pol_Rpb6 PF01192.22 VBB25275.1 - 1.6e-13 50.4 0.1 2.4e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 VBB25275.1 - 0.058 13.2 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) VHP PF02209.19 VBB25276.1 - 8.5e-16 57.7 0.7 2.2e-15 56.4 0.7 1.8 1 0 0 1 1 1 1 Villin headpiece domain Gelsolin PF00626.22 VBB25276.1 - 8.9e-15 54.4 0.2 0.00034 20.5 0.0 4.8 5 0 0 5 5 5 3 Gelsolin repeat Patched PF02460.18 VBB25277.1 - 7.4e-228 758.6 3.9 4e-134 448.6 10.4 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 VBB25277.1 - 2.9e-26 92.2 3.4 2.9e-26 92.2 3.4 3.5 3 2 1 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation Ribosomal_S15 PF00312.22 VBB25278.1 - 9.3e-10 38.6 0.2 2.3e-09 37.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3718 PF12514.8 VBB25278.1 - 0.035 14.3 0.1 0.083 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) FTCD_C PF04961.12 VBB25278.1 - 0.088 12.6 0.3 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase ERM PF00769.19 VBB25279.1 - 2.9e-54 184.5 59.5 2.9e-54 184.5 59.5 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 VBB25279.1 - 1.4e-27 95.9 0.1 6.5e-27 93.8 0.0 2.2 1 1 1 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 VBB25279.1 - 4e-27 95.0 0.0 4e-27 95.0 0.0 3.1 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.10 VBB25279.1 - 1.6e-13 50.4 0.1 5.5e-13 48.6 0.1 2.0 1 0 0 1 1 1 1 FERM N-terminal domain ACBP PF00887.19 VBB25279.1 - 0.015 15.5 0.0 0.015 15.5 0.0 3.1 3 0 0 3 3 3 0 Acyl CoA binding protein NPV_P10 PF05531.12 VBB25279.1 - 0.19 12.2 13.4 5.4 7.5 1.0 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LRR_8 PF13855.6 VBB25281.1 - 2e-24 85.1 4.8 4.4e-08 32.8 0.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 VBB25281.1 - 3.4e-18 65.5 7.1 1.4e-06 28.5 2.6 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB25281.1 - 9.3e-05 22.5 11.5 6.9 7.6 0.3 6.7 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 VBB25281.1 - 0.00051 19.6 2.2 1.2 8.6 0.5 3.5 2 2 2 4 4 4 2 Leucine-rich repeat LRRCT PF01463.24 VBB25281.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain TILa PF12714.7 VBB25281.1 - 0.082 12.9 2.4 0.25 11.3 2.4 1.8 1 0 0 1 1 1 0 TILa domain LRR_6 PF13516.6 VBB25281.1 - 0.38 10.9 14.3 9.3 6.6 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat LRRNT PF01462.18 VBB25281.1 - 1.3 8.8 11.2 0.098 12.3 5.3 2.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DHHC PF01529.20 VBB25282.1 - 5.5e-26 91.2 18.3 5.5e-26 91.2 18.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.6 VBB25282.1 - 0.00053 20.4 5.9 0.0035 17.7 1.8 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF4199) TatC PF00902.18 VBB25282.1 - 0.0035 17.2 0.5 0.0047 16.8 0.5 1.3 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Comm PF15957.5 VBB25282.1 - 0.0071 16.7 0.5 0.0071 16.7 0.5 2.3 2 0 0 2 2 2 1 Commissureless BH4 PF02180.17 VBB25282.1 - 0.16 11.8 0.4 0.16 11.8 0.4 1.7 2 0 0 2 2 2 0 Bcl-2 homology region 4 Med3 PF11593.8 VBB25282.1 - 0.68 9.1 9.5 0.95 8.6 9.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FERM_M PF00373.18 VBB25283.1 - 4.4e-19 69.0 0.2 8.6e-19 68.1 0.2 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 VBB25283.1 - 3.5e-14 52.5 0.3 1e-13 51.0 0.3 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 VBB25283.1 - 2.1e-11 44.1 0.3 4.4e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain RA PF00788.23 VBB25284.1 - 2e-20 73.2 0.0 2.7e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain BAP PF06639.11 VBB25284.1 - 0.065 13.6 0.2 2.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Basal layer antifungal peptide (BAP) PH_RBD PF12068.8 VBB25284.1 - 0.07 12.6 1.2 0.12 11.9 1.2 1.3 1 0 0 1 1 1 0 Rab-binding domain (RBD) Tetraspanin PF00335.20 VBB25285.1 - 7.2e-05 22.6 4.9 0.00025 20.8 0.9 2.3 1 1 1 2 2 2 2 Tetraspanin family Elongin_A PF06881.11 VBB25285.1 - 0.00049 20.6 0.4 0.0013 19.2 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4199 PF13858.6 VBB25285.1 - 0.0067 16.8 3.6 0.015 15.7 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) F-box-like PF12937.7 VBB25285.1 - 0.0099 15.8 0.1 0.035 14.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like Methyltransf_10 PF05971.12 VBB25285.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase NMN_transporter PF04973.12 VBB25285.1 - 0.13 12.2 3.1 0.22 11.5 3.1 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DPPIV_N PF00930.21 VBB25286.1 - 3.6e-47 160.9 0.0 8.8e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 VBB25286.1 - 6.8e-46 156.4 0.0 1.3e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family SCAPER_N PF16501.5 VBB25286.1 - 2.3e-21 75.7 0.6 1.1e-20 73.5 0.6 2.2 1 0 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum Atx10homo_assoc PF09759.9 VBB25286.1 - 8.9e-18 64.2 0.0 4.3e-17 61.9 0.0 2.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DLH PF01738.18 VBB25286.1 - 2.2e-06 27.4 0.0 8.5e-06 25.5 0.0 2.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 VBB25286.1 - 0.00032 21.4 0.7 0.001 19.7 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Stathmin PF00836.19 VBB25286.1 - 0.00092 19.2 26.3 0.00092 19.2 26.3 5.1 5 0 0 5 5 4 1 Stathmin family Hydrolase_4 PF12146.8 VBB25286.1 - 0.0013 18.0 0.1 0.006 15.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 VBB25286.1 - 0.0021 17.7 0.1 0.0021 17.7 0.1 3.7 2 2 2 4 4 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 VBB25286.1 - 0.0066 16.1 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 VBB25286.1 - 0.037 13.7 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative esterase polyprenyl_synt PF00348.17 VBB25287.1 - 2.9e-73 246.1 0.2 3.3e-73 245.9 0.2 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase LRR_8 PF13855.6 VBB25289.1 - 1.7e-42 143.0 56.0 9.6e-12 44.5 2.4 7.2 6 2 2 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 VBB25289.1 - 4.3e-21 74.7 63.8 1.3e-05 25.5 4.9 8.8 7 2 3 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB25289.1 - 1.5e-15 57.3 11.4 1.3e-06 28.4 0.2 4.6 4 1 1 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 VBB25289.1 - 2.1e-09 36.6 54.3 0.15 12.7 0.1 13.1 14 1 0 14 14 14 5 Leucine Rich Repeat LRR_9 PF14580.6 VBB25289.1 - 0.00044 19.8 22.1 0.001 18.6 7.5 3.8 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 VBB25289.1 - 0.038 14.1 0.3 0.23 11.6 0.1 11.4 13 0 0 13 13 13 0 Leucine Rich repeat Golgin_A5 PF09787.9 VBB25290.1 - 2.7e-47 161.7 22.2 2.7e-47 161.7 22.2 2.5 2 0 0 2 2 2 1 Golgin subfamily A member 5 Vta1 PF04652.16 VBB25290.1 - 1.2e-46 158.2 0.5 1.2e-46 158.2 0.5 3.6 4 1 0 4 4 4 1 Vta1 like RhoGAP PF00620.27 VBB25290.1 - 8.5e-28 97.1 0.2 8.5e-28 97.1 0.2 3.0 3 0 0 3 3 3 1 RhoGAP domain Bacillus_HBL PF05791.11 VBB25290.1 - 0.0017 18.2 7.3 0.0017 18.2 7.3 4.2 2 2 2 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) Vta1_C PF18097.1 VBB25290.1 - 0.23 11.2 2.3 0.3 10.8 0.3 2.3 2 0 0 2 2 2 0 Vta1 C-terminal domain CH PF00307.31 VBB25291.1 - 7.3e-22 77.6 0.1 9.9e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 VBB25291.1 - 9.4e-10 38.0 4.5 1.6e-09 37.2 4.5 1.4 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 VBB25291.1 - 5.6e-06 26.1 0.0 8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain ZipA_C PF04354.13 VBB25291.1 - 0.0092 15.8 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain CDC24 PF06395.11 VBB25291.1 - 0.062 13.6 0.2 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 CDC24 Calponin Hormone_recep PF00104.30 VBB25292.1 - 3e-31 108.6 0.1 6e-31 107.6 0.1 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 VBB25292.1 - 4.1e-28 97.6 16.7 4.1e-28 97.6 16.7 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) K_channel_TID PF07941.11 VBB25292.1 - 0.51 10.8 12.9 3.3 8.2 4.6 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF5423 PF17461.2 VBB25292.1 - 7.3 5.3 8.8 18 4.0 8.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5423) TPR_17 PF13431.6 VBB25294.1 - 8.8e-09 35.2 0.6 3.4e-05 23.9 0.8 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB25294.1 - 3.3e-07 30.7 1.6 5.2e-07 30.1 1.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB25294.1 - 4e-07 29.7 2.9 0.049 13.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB25294.1 - 6.7e-06 25.7 0.9 0.054 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB25294.1 - 7.9e-05 22.6 0.1 0.0072 16.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB25294.1 - 0.00019 21.5 0.6 0.076 13.2 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB25294.1 - 0.00049 19.7 0.1 0.058 13.1 0.0 2.4 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 VBB25294.1 - 0.0058 16.8 1.0 0.067 13.4 0.6 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB25294.1 - 0.0059 17.2 1.0 9.3 7.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB25294.1 - 0.0089 16.3 1.2 0.033 14.5 1.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25294.1 - 0.012 16.2 0.7 4.2 8.1 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 VBB25294.1 - 0.02 14.1 0.0 0.062 12.5 0.0 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 VBB25294.1 - 0.042 14.2 0.4 0.063 13.6 0.4 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 VBB25294.1 - 0.045 14.6 0.3 3 8.9 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat Beach PF02138.18 VBB25295.1 - 1.3e-123 411.8 0.1 2.6e-123 410.8 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain ATG7_N PF16420.5 VBB25295.1 - 9.7e-54 183.0 0.1 1.9e-53 182.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus UQ_con PF00179.26 VBB25295.1 - 1.3e-42 144.8 0.0 1.3e-41 141.5 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RhoGAP PF00620.27 VBB25295.1 - 1.6e-40 138.4 0.0 4e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain ThiF PF00899.21 VBB25295.1 - 1.2e-39 136.1 0.1 8.6e-39 133.3 0.0 2.4 2 0 0 2 2 2 1 ThiF family MINDY_DUB PF04424.13 VBB25295.1 - 2.2e-32 111.5 0.2 1.4e-31 109.0 0.0 2.6 2 0 0 2 2 2 1 MINDY deubiquitinase FYVE PF01363.21 VBB25295.1 - 8.8e-17 61.0 14.6 4.1e-16 58.9 14.6 2.3 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 VBB25295.1 - 2.4e-12 46.8 0.1 6.3e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Oxidored-like PF09791.9 VBB25295.1 - 1.5e-06 27.7 8.3 2.6e-06 27.0 6.4 2.4 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal WD40 PF00400.32 VBB25295.1 - 2.5e-05 24.9 11.4 0.027 15.3 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4800 PF16057.5 VBB25295.1 - 0.012 14.8 0.2 0.035 13.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 VBB25295.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily zf-RING_UBOX PF13445.6 VBB25295.1 - 2.9 8.0 8.2 11 6.1 8.2 2.1 1 0 0 1 1 1 0 RING-type zinc-finger ubiquitin PF00240.23 VBB25296.1 - 1.1e-07 31.5 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 VBB25296.1 - 0.0072 16.8 0.0 0.037 14.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 VBB25296.1 - 0.048 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like FNIP_M PF14637.6 VBB25297.1 - 3.7e-63 213.6 2.1 5.3e-63 213.0 1.4 1.7 2 0 0 2 2 2 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 VBB25297.1 - 8.1e-32 110.4 0.0 1.5e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 VBB25297.1 - 0.16 12.9 7.6 0.59 11.1 0.2 3.1 2 1 1 3 3 3 0 Folliculin-interacting protein N-terminus HSP90 PF00183.18 VBB25299.1 - 4.4e-222 738.6 30.2 4.4e-222 738.6 30.2 1.5 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 VBB25299.1 - 1.7e-10 41.4 0.2 4.9e-10 39.9 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 VBB25299.1 - 4.3e-09 36.3 2.0 9.2e-09 35.2 0.0 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L10 PF00466.20 VBB25299.1 - 0.074 13.2 3.0 7.7 6.7 0.2 3.0 3 0 0 3 3 3 0 Ribosomal protein L10 Peptidase_A22B PF04258.13 VBB25300.1 - 1.4e-82 277.4 8.1 4.6e-82 275.7 8.1 1.7 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 VBB25300.1 - 8e-05 22.3 3.4 0.00015 21.4 3.4 1.4 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 VBB25300.1 - 0.13 11.0 2.0 1.6 7.4 0.1 2.7 2 0 0 2 2 2 0 Presenilin GATA PF00320.27 VBB25301.1 - 9.3e-13 47.6 7.5 9.3e-13 47.6 7.5 1.9 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 VBB25301.1 - 0.0062 16.0 0.7 0.021 14.3 0.7 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding EMP70 PF02990.16 VBB25302.1 - 2.6e-124 415.7 15.4 2.6e-119 399.3 1.6 2.1 1 1 1 2 2 2 2 Endomembrane protein 70 Amidase PF01425.21 VBB25303.1 - 1.2e-103 347.5 0.0 1.4e-103 347.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DEAD PF00270.29 VBB25304.1 - 1e-51 175.2 0.0 7e-51 172.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB25304.1 - 9.8e-27 93.5 0.0 1e-25 90.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CH PF00307.31 VBB25304.1 - 6.5e-22 77.8 2.1 5e-13 49.2 0.1 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain Ala_racemase_N PF01168.20 VBB25305.1 - 2.6e-17 63.2 0.0 3.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain COMMD1_N PF17221.3 VBB25305.1 - 0.053 13.8 0.2 0.14 12.4 0.2 1.8 1 0 0 1 1 1 0 COMMD1 N-terminal domain TPT PF03151.16 VBB25306.1 - 1.4e-19 70.6 16.5 1.7e-19 70.3 16.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 VBB25306.1 - 0.0011 19.1 33.4 0.018 15.2 12.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family tRNA-synt_2b PF00587.25 VBB25307.1 - 2.2e-27 96.2 0.0 4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 VBB25308.1 - 1.9e-65 220.8 0.0 3.2e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25308.1 - 2.7e-35 121.9 0.0 4.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 VBB25308.1 - 3e-07 30.1 0.1 6.5e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 VBB25308.1 - 4e-07 29.6 0.0 1.1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB25308.1 - 3.5e-05 23.3 0.3 7.5e-05 22.2 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 VBB25308.1 - 0.00018 21.2 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 VBB25308.1 - 0.00027 21.0 0.0 0.0089 16.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 VBB25308.1 - 0.00064 19.4 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 VBB25308.1 - 0.017 14.1 0.1 0.037 13.0 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Zincin_1 PF06262.11 VBB25308.1 - 0.15 12.2 0.1 0.42 10.7 0.1 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase Homeodomain PF00046.29 VBB25309.1 - 8e-17 60.8 7.7 8.2e-17 60.8 2.5 2.4 1 1 1 2 2 2 1 Homeodomain Phage_C PF12025.8 VBB25309.1 - 0.087 12.7 0.2 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Phage protein C Ank_2 PF12796.7 VBB25310.1 - 1.4e-08 35.2 0.1 6.2e-08 33.1 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB25310.1 - 5.4e-08 32.5 0.9 0.17 12.6 0.3 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 VBB25310.1 - 7e-07 29.4 0.3 0.37 11.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 VBB25310.1 - 5.1e-06 26.9 0.2 0.13 12.9 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB25310.1 - 0.0019 18.5 0.4 0.13 12.6 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CTP_transf_like PF01467.26 VBB25311.1 - 1.5e-31 109.6 0.0 3e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like Cadherin PF00028.17 VBB25312.1 - 8.8e-50 167.1 0.8 9.5e-14 51.6 0.0 8.4 8 0 0 8 8 8 6 Cadherin domain Pkinase PF00069.25 VBB25313.1 - 9.7e-74 248.1 0.0 1.1e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25313.1 - 4.3e-33 114.7 0.0 6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB25313.1 - 9.9e-06 25.1 0.0 2.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 VBB25313.1 - 0.00067 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 VBB25313.1 - 0.002 17.2 0.1 0.0039 16.2 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB25313.1 - 0.0024 17.8 0.0 0.0075 16.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 VBB25313.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 VBB25313.1 - 0.069 12.5 0.2 0.23 10.8 0.2 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 VBB25314.1 - 2.2e-69 233.7 0.0 2.7e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25314.1 - 4.2e-33 114.7 0.0 7.5e-33 113.9 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 VBB25314.1 - 2.9e-05 23.5 0.3 6.6e-05 22.4 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB25314.1 - 0.0021 17.1 0.2 0.025 13.6 0.2 2.5 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 VBB25314.1 - 0.0023 17.9 0.5 0.016 15.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB25314.1 - 0.033 13.8 1.3 0.098 12.2 0.3 1.9 1 1 1 2 2 2 0 RIO1 family Kinase-like PF14531.6 VBB25314.1 - 0.035 13.4 0.0 0.065 12.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Guanylate_kin PF00625.21 VBB25315.1 - 8.7e-10 38.6 0.3 4.7e-09 36.2 0.1 2.0 2 0 0 2 2 2 1 Guanylate kinase PDZ_6 PF17820.1 VBB25315.1 - 0.14 12.0 0.1 0.41 10.5 0.1 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 VBB25316.1 - 1.7e-58 195.0 17.0 2.2e-16 59.9 0.0 5.1 5 1 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 VBB25316.1 - 6.6e-43 144.4 13.9 2.4e-11 43.3 0.3 4.6 5 0 0 5 5 5 4 PDZ domain PDZ_2 PF13180.6 VBB25316.1 - 5.5e-21 74.7 0.7 0.00045 20.5 0.1 4.5 4 0 0 4 4 4 4 PDZ domain WW PF00397.26 VBB25316.1 - 1.1e-17 63.8 5.8 6.9e-11 42.0 1.7 2.5 2 0 0 2 2 2 2 WW domain Cadherin PF00028.17 VBB25317.1 - 2.3e-127 415.8 16.8 9.2e-21 74.1 0.1 8.9 9 0 0 9 9 9 8 Cadherin domain Laminin_G_2 PF02210.24 VBB25317.1 - 6.6e-21 75.2 0.0 8.4e-18 65.2 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 VBB25317.1 - 1.4e-12 47.9 0.0 6.5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain Cadherin_2 PF08266.12 VBB25317.1 - 6.1e-11 42.0 3.0 0.32 10.9 0.0 6.2 5 0 0 5 5 5 4 Cadherin-like Cadherin_3 PF16184.5 VBB25317.1 - 2.8e-09 36.9 16.0 0.4 10.7 0.0 7.8 8 0 0 8 8 8 4 Cadherin-like EGF PF00008.27 VBB25317.1 - 1.2e-06 28.7 8.7 1.2e-06 28.7 8.7 8.6 8 1 0 8 8 8 4 EGF-like domain Cadherin_4 PF17803.1 VBB25317.1 - 8.6e-06 26.3 19.1 0.3 11.7 0.0 6.4 6 0 0 6 6 6 2 Bacterial cadherin-like domain hEGF PF12661.7 VBB25317.1 - 0.0014 19.2 9.5 0.0018 18.9 4.8 8.8 9 0 0 9 9 9 4 Human growth factor-like EGF EGF_2 PF07974.13 VBB25317.1 - 0.0016 18.8 9.6 0.0016 18.8 9.6 8.5 8 1 1 9 9 9 2 EGF-like domain Pkinase PF00069.25 VBB25319.1 - 4.5e-52 177.0 0.1 5.9e-52 176.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25319.1 - 5.4e-23 81.6 0.4 1.2e-21 77.1 0.4 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB25319.1 - 3.4e-05 23.3 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB25319.1 - 0.013 14.5 0.2 0.024 13.6 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain JmjC PF02373.22 VBB25320.1 - 1.5e-13 51.2 0.1 4.8e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 VBB25320.1 - 0.0068 16.1 0.1 0.14 11.8 0.0 2.6 3 0 0 3 3 3 1 Cupin-like domain IFR3_antag PF14754.6 VBB25320.1 - 0.075 12.2 1.2 0.15 11.2 1.2 1.4 1 0 0 1 1 1 0 Papain-like auto-proteinase FYVE PF01363.21 VBB25320.1 - 0.1 12.8 5.1 0.31 11.2 5.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger Zf_RING PF16744.5 VBB25320.1 - 0.24 11.5 8.1 0.67 10.1 4.1 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Thioredoxin PF00085.20 VBB25321.1 - 3.6e-77 255.0 8.6 1.1e-22 79.9 0.5 4.8 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_2 PF13098.6 VBB25321.1 - 2e-22 79.7 7.0 3.6e-09 37.0 0.2 5.6 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 VBB25321.1 - 6.3e-18 64.7 1.3 4.1e-06 26.9 0.1 3.7 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_6 PF13848.6 VBB25321.1 - 9.7e-12 45.2 1.1 1.6e-05 24.9 0.1 3.6 4 0 0 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.21 VBB25321.1 - 1.6e-11 44.2 1.8 0.0049 16.8 0.0 3.6 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_8 PF13905.6 VBB25321.1 - 1.3e-08 35.1 5.5 0.49 10.7 0.1 5.9 4 3 2 6 6 6 2 Thioredoxin-like Redoxin PF08534.10 VBB25321.1 - 2.5e-08 33.8 3.0 0.13 11.9 0.2 3.6 3 0 0 3 3 3 3 Redoxin OST3_OST6 PF04756.13 VBB25321.1 - 8.3e-08 31.9 5.9 0.0046 16.3 0.6 4.0 2 2 1 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 VBB25321.1 - 8.9e-08 32.1 0.0 0.00065 19.7 0.0 4.1 4 0 0 4 4 4 1 Thioredoxin domain TraF PF13728.6 VBB25321.1 - 2.3e-05 24.4 1.1 0.19 11.5 0.1 3.8 3 1 0 3 3 3 2 F plasmid transfer operon protein HyaE PF07449.11 VBB25321.1 - 6e-05 23.0 0.0 0.39 10.7 0.0 4.3 4 2 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 VBB25321.1 - 0.00028 21.0 11.6 0.44 10.8 0.3 4.0 4 0 0 4 4 4 3 Glutaredoxin DUF953 PF06110.11 VBB25321.1 - 0.04 13.5 3.0 3.5 7.3 0.2 3.1 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Hydrolase PF00702.26 VBB25321.1 - 0.065 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cytochrom_B_C PF00032.17 VBB25321.1 - 0.15 12.4 0.0 1.3 9.4 0.0 2.4 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD DUF5342 PF17277.2 VBB25321.1 - 0.84 10.0 2.6 15 6.0 0.0 3.3 4 0 0 4 4 3 0 Family of unknown function (DUF5342) Ribosomal_S18 PF01084.20 VBB25322.1 - 1.1e-14 54.4 0.1 1.7e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 DUF5547 PF17701.1 VBB25322.1 - 0.17 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5547) RRM_1 PF00076.22 VBB25323.1 - 9.9e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 VBB25323.1 - 4.6e-06 27.3 0.1 1.1e-05 26.1 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 VBB25323.1 - 5.5e-06 26.2 1.9 5.5e-06 26.2 1.9 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 VBB25323.1 - 0.0023 17.7 3.2 0.0069 16.2 3.2 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 VBB25323.1 - 0.0033 17.6 0.3 0.0089 16.2 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger containing family Nup35_RRM_2 PF14605.6 VBB25323.1 - 0.0044 17.0 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 VBB25323.1 - 0.0057 16.5 3.3 0.0057 16.5 3.3 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 VBB25323.1 - 0.0098 16.3 1.1 0.0098 16.3 1.1 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger FYVE PF01363.21 VBB25323.1 - 0.014 15.5 1.0 0.014 15.5 1.0 1.9 2 0 0 2 2 2 0 FYVE zinc finger BTB_2 PF02214.22 VBB25324.1 - 1.2e-19 70.4 0.1 3.2e-19 69.1 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 VBB25324.1 - 1.7e-05 25.0 0.0 3.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MRP-L27 PF09809.9 VBB25325.1 - 7e-11 42.0 0.0 4e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 Lipase_GDSL_2 PF13472.6 VBB25325.1 - 2.2e-05 24.9 0.0 0.00096 19.6 0.0 2.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 VBB25325.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HSP20 PF00011.21 VBB25326.1 - 4e-16 59.0 0.0 8.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB25326.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA hEGF PF12661.7 VBB25327.1 - 3.5e-05 24.2 5.1 0.00013 22.4 5.1 2.1 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.27 VBB25327.1 - 0.00017 21.8 6.1 0.00017 21.8 6.1 2.0 2 0 0 2 2 2 1 EGF-like domain DUF1794 PF08768.11 VBB25327.1 - 0.00024 21.1 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) EGF_2 PF07974.13 VBB25327.1 - 0.00075 19.8 7.6 0.00075 19.8 7.6 2.0 2 0 0 2 2 2 1 EGF-like domain ShK PF01549.24 VBB25327.1 - 0.001 19.5 7.2 0.001 19.5 7.2 2.6 2 1 1 3 3 3 1 ShK domain-like Glyco_transf_20 PF00982.21 VBB25328.1 - 1.7e-66 224.8 2.5 1.2e-40 139.7 0.0 3.4 1 1 1 2 2 2 2 Glycosyltransferase family 20 T6PP_N PF18572.1 VBB25328.1 - 3.7e-36 123.0 2.4 7.5e-36 122.0 2.4 1.6 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain ECF_trnsprt PF12822.7 VBB25329.1 - 2.6 8.1 14.8 5.1 7.2 14.8 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Ssu72 PF04722.13 VBB25330.1 - 1.7e-80 269.1 0.1 1.9e-80 269.0 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein PITH PF06201.13 VBB25332.1 - 0.029 14.6 0.3 0.032 14.4 0.3 1.2 1 0 0 1 1 1 0 PITH domain DUF3460 PF11943.8 VBB25332.1 - 0.23 11.8 1.0 0.56 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) WASH_WAHD PF11945.8 VBB25333.1 - 1.4e-21 77.3 2.2 2.2e-21 76.7 2.2 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex KxDL PF10241.9 VBB25333.1 - 0.00079 19.7 0.7 0.0022 18.2 0.7 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein CENP-T_C PF15511.6 VBB25333.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Synuclein PF01387.17 VBB25333.1 - 0.063 13.5 1.0 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Synuclein NSP16 PF06460.12 VBB25333.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 CAP_N PF01213.19 VBB25333.1 - 0.85 9.0 9.5 0.078 12.5 1.6 2.8 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal PIG-P PF08510.12 VBB25334.1 - 3.2e-19 69.0 3.3 3.9e-19 68.7 3.3 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 VBB25334.1 - 1.8e-05 24.9 9.0 2.6e-05 24.4 9.0 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MMR_HSR1 PF01926.23 VBB25335.1 - 1.5e-08 34.7 0.0 2.6e-07 30.7 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB25335.1 - 0.0023 17.5 0.1 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 VBB25335.1 - 0.0032 17.0 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 VBB25335.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Dynamin family GPCR_chapero_1 PF11904.8 VBB25335.1 - 0.071 12.5 0.3 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 GPCR-chaperone RsgA_GTPase PF03193.16 VBB25335.1 - 0.079 12.9 0.0 0.36 10.7 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase PRELI PF04707.14 VBB25336.1 - 4e-32 111.2 0.3 8.4e-32 110.2 0.3 1.5 1 0 0 1 1 1 1 PRELI-like family PXA PF02194.15 VBB25336.1 - 7.1e-24 84.8 1.5 1.6e-23 83.6 1.5 1.7 1 0 0 1 1 1 1 PXA domain PX PF00787.24 VBB25336.1 - 3.4e-11 43.1 0.9 1.3e-10 41.2 0.4 2.3 2 0 0 2 2 2 1 PX domain RGS PF00615.19 VBB25336.1 - 2.5e-08 34.2 1.1 9.8e-07 29.1 0.0 3.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain Nexin_C PF08628.12 VBB25336.1 - 0.00012 22.7 0.1 0.0008 20.0 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal Porphobil_deam PF01379.20 VBB25336.1 - 0.006 16.1 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain SQS_PSY PF00494.19 VBB25337.1 - 9.8e-35 120.3 0.1 1.3e-34 119.9 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase MMgT PF10270.9 VBB25337.1 - 1.2e-15 57.7 0.0 3.3e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Membrane magnesium transporter PG_binding_3 PF09374.10 VBB25337.1 - 0.15 12.3 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Predicted Peptidoglycan domain Voltage_CLC PF00654.20 VBB25338.1 - 4.8e-75 253.0 27.3 4.8e-75 253.0 27.3 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 VBB25338.1 - 4.8e-06 26.9 0.0 0.027 14.9 0.0 3.0 2 0 0 2 2 2 2 CBS domain DGF-1_4 PF11024.8 VBB25339.1 - 0.37 11.6 4.3 1.2 10.0 4.3 1.8 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 AAA_12 PF13087.6 VBB25340.1 - 6.8e-41 140.1 0.3 6.8e-41 140.1 0.3 2.0 2 0 0 2 2 2 1 AAA domain Dna2 PF08696.11 VBB25340.1 - 8e-38 130.3 0.1 1.8e-37 129.2 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 VBB25340.1 - 8.2e-30 104.4 6.5 2e-15 57.3 0.2 3.4 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 VBB25340.1 - 1.3e-12 47.8 0.0 3.7e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 VBB25340.1 - 4.4e-11 43.2 0.0 7.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 VBB25340.1 - 7.1e-08 32.9 0.4 3.1e-07 30.8 0.1 2.3 3 0 0 3 3 2 1 AAA domain Cas_Cas4 PF01930.17 VBB25340.1 - 9.4e-08 32.3 0.2 2e-05 24.7 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function DUF83 Csa1 PF06023.12 VBB25340.1 - 0.0003 20.3 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 Helicase_RecD PF05127.14 VBB25340.1 - 0.00081 19.3 0.0 0.0024 17.7 0.0 1.9 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 VBB25340.1 - 0.0023 17.2 0.0 0.0023 17.2 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 VBB25340.1 - 0.009 15.8 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 VBB25340.1 - 0.012 15.3 0.4 10 5.8 0.0 3.5 2 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UreF PF01730.16 VBB25340.1 - 0.037 14.6 0.0 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 UreF Peptidase_A17 PF05380.13 VBB25340.1 - 0.046 13.7 1.9 0.37 10.8 0.9 2.5 2 0 0 2 2 2 0 Pao retrotransposon peptidase UvrD-helicase PF00580.21 VBB25340.1 - 0.21 11.0 0.1 0.21 11.0 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Peptidase_M13_N PF05649.13 VBB25341.1 - 2.6e-105 353.3 5.2 3.9e-105 352.7 5.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 VBB25341.1 - 1.5e-78 263.1 0.1 2.9e-78 262.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 T2SSM PF04612.12 VBB25341.1 - 0.056 13.5 0.5 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M SNAPc_SNAP43 PF09808.9 VBB25342.1 - 7.6e-39 133.6 1.8 1.4e-38 132.7 1.8 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Voltage_CLC PF00654.20 VBB25343.1 - 9.9e-95 317.8 22.4 1.8e-94 316.9 19.8 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 VBB25343.1 - 6.8e-15 55.3 0.3 1.3e-08 35.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain TusA PF01206.17 VBB25343.1 - 0.17 11.8 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Sulfurtransferase TusA N1221 PF07923.13 VBB25344.1 - 3.7e-19 69.0 0.3 5.3e-19 68.5 0.3 1.2 1 0 0 1 1 1 1 N1221-like protein GLF PF03275.13 VBB25345.1 - 3.4e-05 23.7 3.7 0.66 9.7 0.2 3.3 1 1 1 3 3 3 3 UDP-galactopyranose mutase Corazonin PF17308.2 VBB25345.1 - 0.057 13.8 6.7 0.12 12.8 6.7 1.5 1 0 0 1 1 1 0 Pro-corazonin Amino_oxidase PF01593.24 VBB25345.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF2457 PF10446.9 VBB25345.1 - 0.27 10.4 8.1 0.38 9.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Secretin_N_2 PF07655.13 VBB25345.1 - 1.6 9.3 9.6 2.9 8.5 9.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.13 VBB25345.1 - 5.3 5.3 6.4 7.2 4.8 6.4 1.1 1 0 0 1 1 1 0 Menin Lectin_C PF00059.21 VBB25346.1 - 3.2e-07 31.0 0.3 4e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 Lectin C-type domain PTCB-BRCT PF12738.7 VBB25346.1 - 0.046 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain FH2 PF02181.23 VBB25350.1 - 1.1e-24 87.2 4.8 9.9e-15 54.5 0.6 2.8 2 1 1 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 VBB25350.1 - 5.3e-08 32.7 1.4 5.3e-08 32.7 1.4 2.0 2 1 0 2 2 2 1 Diaphanous FH3 Domain TB2_DP1_HVA22 PF03134.19 VBB25351.1 - 4.5e-25 87.4 5.6 4.5e-25 87.4 5.6 1.8 2 1 1 3 3 3 1 TB2/DP1, HVA22 family DUF378 PF04070.12 VBB25351.1 - 0.025 14.4 0.8 0.085 12.8 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF378) Pkinase_Tyr PF07714.17 VBB25353.1 - 5.4e-89 297.9 0.0 7.8e-89 297.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB25353.1 - 1.9e-39 135.6 0.1 2.6e-36 125.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Haspin_kinase PF12330.8 VBB25353.1 - 0.0019 17.2 0.1 0.0031 16.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 VBB25353.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 VBB25353.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 VBB25353.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCCH PF00642.24 VBB25354.1 - 2.1e-17 62.6 9.3 5e-10 39.0 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB25354.1 - 6.1e-09 35.7 10.1 0.00025 21.0 0.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB25354.1 - 7.1e-06 25.7 8.1 0.00072 19.3 0.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 VBB25354.1 - 0.0011 19.3 8.7 0.07 13.6 0.8 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger DUF913 PF06025.12 VBB25354.1 - 0.022 13.8 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Torus PF16131.5 VBB25354.1 - 0.026 15.2 6.3 1.4 9.7 0.8 2.5 1 1 1 2 2 2 0 Torus domain zf-CCHH PF10283.9 VBB25354.1 - 9 6.4 9.5 16 5.6 0.7 2.9 2 0 0 2 2 2 0 PBZ domain Pkinase PF00069.25 VBB25357.1 - 2.4e-21 76.3 0.0 3.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25357.1 - 9.3e-09 34.9 0.0 1.4e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25357.1 - 0.00022 20.1 0.1 0.00086 18.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Rbsn PF11464.8 VBB25357.1 - 0.27 11.0 2.0 0.83 9.4 0.3 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain zf-CCCH_2 PF14608.6 VBB25358.1 - 1.1e-17 63.8 49.4 3.6e-05 24.1 6.3 5.3 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger PWI PF01480.17 VBB25358.1 - 9.9e-05 22.6 0.7 0.00019 21.7 0.7 1.4 1 0 0 1 1 1 1 PWI domain zf-C3H1 PF10650.9 VBB25358.1 - 0.17 11.6 2.5 1.1 9.0 0.2 3.1 3 0 0 3 3 3 0 Putative zinc-finger domain Innexin PF00876.18 VBB25359.1 - 2.8e-88 296.6 15.5 1.1e-86 291.3 15.5 2.1 1 1 0 1 1 1 1 Innexin OATP PF03137.20 VBB25360.1 - 4.7e-153 510.4 18.7 6.7e-153 509.9 18.7 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 VBB25360.1 - 1.9e-23 83.0 24.8 2.1e-21 76.3 19.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 VBB25360.1 - 0.011 15.5 1.1 0.033 13.9 0.1 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Patatin PF01734.22 VBB25362.1 - 6.7e-16 59.1 2.0 5.2e-14 52.9 2.0 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase FERM_F1 PF18379.1 VBB25363.1 - 0.0043 17.0 0.0 0.0047 16.9 0.0 1.1 1 0 0 1 1 1 1 FERM F1 ubiquitin-like domain Cullin PF00888.22 VBB25364.1 - 2.4e-156 522.0 3.0 2.4e-156 522.0 3.0 1.4 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 VBB25364.1 - 7.3e-21 74.0 8.2 2.2e-10 40.4 0.7 3.3 3 0 0 3 3 3 2 Cullin protein neddylation domain HTH_34 PF13601.6 VBB25364.1 - 0.0026 17.9 0.2 0.0091 16.2 0.2 2.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain HbrB PF08539.11 VBB25364.1 - 0.0033 17.5 1.1 0.019 14.9 0.1 2.9 2 1 0 2 2 2 1 HbrB-like Ribosomal_L28 PF00830.19 VBB25364.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L28 family Anillin PF08174.11 VBB25365.1 - 7.1e-19 68.6 0.0 2.3e-18 67.0 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 VBB25365.1 - 1.8e-10 41.3 0.2 1.8e-09 38.0 0.0 2.8 3 0 0 3 3 3 1 PH domain Pan3_PK PF18101.1 VBB25366.1 - 2e-63 212.5 0.5 3.3e-63 211.8 0.5 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 VBB25366.1 - 0.00099 18.5 0.0 0.0023 17.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain PB1 PF00564.24 VBB25366.1 - 0.082 12.8 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 PB1 domain Calreticulin PF00262.18 VBB25367.1 - 7.5e-152 505.4 15.6 7.5e-152 505.4 15.6 1.5 2 0 0 2 2 2 1 Calreticulin family TRAP_alpha PF03896.16 VBB25367.1 - 0.078 12.2 0.4 0.2 10.9 0.4 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 VBB25367.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Connexin Conotoxin PF02950.17 VBB25367.1 - 5.1 8.2 4.9 16 6.6 0.0 3.1 2 1 0 2 2 2 0 Conotoxin LIN37 PF15306.6 VBB25368.1 - 3.5e-12 46.8 0.5 7.4e-12 45.8 0.3 1.7 1 1 0 1 1 1 1 LIN37 RseC_MucC PF04246.12 VBB25369.1 - 1 9.3 7.7 0.12 12.3 3.4 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ig_mannosidase PF17753.1 VBB25370.1 - 3.7e-10 39.4 0.0 7.9e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 VBB25370.1 - 1.4e-06 27.7 0.0 8.8e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Methyltransf_16 PF10294.9 VBB25371.1 - 4.5e-17 62.3 0.1 7.2e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 VBB25371.1 - 2.3e-08 33.8 0.0 3.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 VBB25371.1 - 3e-08 33.6 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB25371.1 - 1.6e-07 32.0 0.0 2.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB25371.1 - 5.1e-07 29.7 0.0 7.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB25371.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 VBB25371.1 - 0.00011 22.8 0.0 0.00018 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB25371.1 - 0.0022 18.7 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 VBB25371.1 - 0.0047 15.9 0.0 0.0058 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 VBB25371.1 - 0.0054 16.4 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GidB PF02527.15 VBB25371.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.19 VBB25371.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pcc1 PF09341.10 VBB25373.1 - 2.1e-15 56.6 0.0 3.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 Lung_7-TM_R PF06814.13 VBB25375.1 - 1.1e-53 182.4 16.5 1.4e-53 182.1 16.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1761 PF08570.10 VBB25375.1 - 0.45 10.8 8.5 1.1 9.5 8.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Spo7 PF03907.13 VBB25375.1 - 1.3 8.5 7.3 0.33 10.4 3.2 2.0 2 1 0 2 2 2 0 Spo7-like protein DUF3810 PF12725.7 VBB25375.1 - 2.8 7.2 9.5 4.2 6.6 6.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) PD40 PF07676.12 VBB25377.1 - 0.3 11.1 1.3 4.4 7.4 0.4 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat zf-C4 PF00105.18 VBB25378.1 - 5.9e-17 61.9 19.9 2.2e-15 56.9 19.9 2.3 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) 7tm_1 PF00001.21 VBB25380.1 - 6.9e-11 42.0 12.6 1e-06 28.3 2.6 2.3 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB25380.1 - 0.00036 20.0 7.4 0.013 14.9 2.3 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx NB PF04159.13 VBB25380.1 - 0.85 9.7 5.2 17 5.5 0.2 2.4 1 1 1 2 2 2 0 NB glycoprotein DUF4440 PF14534.6 VBB25381.1 - 9.3e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 VBB25381.1 - 4.9e-07 30.3 0.0 6.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 VBB25381.1 - 0.0013 19.3 0.0 0.017 15.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 VBB25381.1 - 0.0032 17.6 0.1 0.066 13.3 0.1 2.1 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 VBB25381.1 - 0.0056 16.9 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 VBB25381.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain DUF4271 PF14093.6 VBB25381.1 - 0.065 13.1 3.6 0.11 12.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) IRS PF02174.17 VBB25382.1 - 2.7e-07 30.4 0.0 1.1e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 PTB domain (IRS-1 type) Zwilch PF09817.9 VBB25383.1 - 3.4e-32 111.7 0.0 5.8e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 RZZ complex, subunit zwilch Mis12 PF05859.12 VBB25383.1 - 0.0011 19.0 0.5 0.013 15.6 0.5 2.4 1 1 0 1 1 1 1 Mis12 protein DUF5418 PF17439.2 VBB25383.1 - 0.22 11.6 9.5 0.014 15.5 3.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5418) Elongin_A PF06881.11 VBB25385.1 - 3.7e-22 78.8 0.4 3.7e-22 78.8 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 VBB25385.1 - 1.9e-12 47.0 0.1 7.4e-12 45.1 0.1 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RRM_1 PF00076.22 VBB25386.1 - 1.9e-05 24.4 0.0 4.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB25386.1 - 0.034 14.2 0.4 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif TAF1_subA PF14929.6 VBB25387.1 - 7.2e-06 25.7 10.0 0.0003 20.3 10.1 2.3 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A EMP24_GP25L PF01105.24 VBB25388.1 - 6e-45 153.4 5.7 1.3e-24 87.2 0.3 2.2 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.6 VBB25388.1 - 0.00017 22.1 0.2 0.31 11.5 0.0 2.4 2 0 0 2 2 2 2 Golgi-dynamics membrane-trafficking DHR10 PF18595.1 VBB25388.1 - 0.15 12.1 1.2 0.78 9.8 0.2 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CathepsinC_exc PF08773.11 VBB25388.1 - 0.32 11.3 1.5 7.5 6.8 0.2 2.5 2 0 0 2 2 2 0 Cathepsin C exclusion domain Pkinase PF00069.25 VBB25389.1 - 2.4e-60 204.1 0.0 2.8e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25389.1 - 2.4e-32 112.3 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 VBB25389.1 - 0.0039 16.8 0.1 0.0071 16.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 VBB25389.1 - 0.012 14.9 0.0 0.033 13.5 0.0 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 VBB25389.1 - 0.018 14.9 0.1 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 VBB25389.1 - 0.087 12.2 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEC1 PF15859.5 VBB25389.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family 7tm_1 PF00001.21 VBB25390.1 - 1.3e-14 54.2 13.5 2.1e-14 53.5 13.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB25390.1 - 2e-07 30.6 11.3 7.8e-07 28.7 11.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx NS3_envE PF02723.14 VBB25390.1 - 0.062 13.4 2.1 3.9 7.6 0.1 3.1 3 0 0 3 3 3 0 Non-structural protein NS3/Small envelope protein E Pkinase PF00069.25 VBB25391.1 - 3.5e-06 26.6 0.0 0.0011 18.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain SPT2 PF08243.11 VBB25392.1 - 1.7e-10 41.4 15.4 1.7e-10 41.4 15.4 3.6 3 1 0 3 3 3 1 SPT2 chromatin protein HUN PF08729.10 VBB25392.1 - 0.11 12.5 12.5 0.34 11.0 12.5 1.8 1 0 0 1 1 1 0 HPC2 and ubinuclein domain DUF3993 PF13158.6 VBB25392.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) PAN_1 PF00024.26 VBB25393.1 - 3.6e-16 58.9 17.3 5.8e-08 32.6 5.0 3.6 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 VBB25393.1 - 0.00047 20.0 9.2 0.27 11.2 1.4 3.8 4 0 0 4 4 4 2 PAN domain Rax2 PF12768.7 VBB25393.1 - 0.073 12.5 2.4 0.17 11.3 0.4 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity PAN_2 PF08276.11 VBB25393.1 - 0.52 10.5 6.8 2.1 8.5 1.5 2.7 2 0 0 2 2 2 0 PAN-like domain CRAL_TRIO PF00650.20 VBB25394.1 - 8.1e-14 51.6 0.1 1.2e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain 7tm_1 PF00001.21 VBB25395.1 - 2e-29 102.8 11.2 2.7e-29 102.3 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MTABC_N PF16185.5 VBB25395.1 - 0.046 13.2 0.7 0.046 13.2 0.7 2.3 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF2116 PF09889.9 VBB25395.1 - 0.063 13.3 1.5 14 5.8 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4131 PF13567.6 VBB25395.1 - 1.5 8.4 7.2 4 7.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RUN PF02759.19 VBB25396.1 - 0.1 12.5 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 RUN domain ALMT PF11744.8 VBB25397.1 - 8.5 5.1 8.8 13 4.5 8.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RRM_1 PF00076.22 VBB25398.1 - 3.2e-27 94.1 0.0 1.2e-16 60.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 VBB25398.1 - 0.0028 17.9 0.3 1.3 9.2 0.0 2.9 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 VBB25398.1 - 0.058 13.5 0.0 0.24 11.5 0.0 2.1 2 1 0 2 2 2 0 RNA recognition motif DUF5053 PF16476.5 VBB25398.1 - 0.094 12.4 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) F-box-like PF12937.7 VBB25399.1 - 9.7e-13 47.8 0.1 9.7e-13 47.8 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 VBB25399.1 - 5.6e-09 35.7 2.3 2.7e-08 33.5 0.0 3.0 3 0 0 3 3 3 1 F-box domain C1_1 PF00130.22 VBB25401.1 - 6.1e-33 112.5 37.8 1.3e-17 63.4 11.2 3.5 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB25401.1 - 0.25 11.7 25.0 0.093 13.1 3.3 3.2 3 0 0 3 3 3 0 C1 domain FYVE_2 PF02318.16 VBB25401.1 - 0.48 10.7 16.3 0.21 11.8 1.6 2.5 3 0 0 3 3 3 0 FYVE-type zinc finger RNA_POL_M_15KD PF02150.16 VBB25401.1 - 1.7 8.6 9.5 0.38 10.7 0.8 2.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF2318 PF10080.9 VBB25401.1 - 9.2 6.4 11.3 0.66 10.1 1.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DUF1041 PF06292.17 VBB25403.1 - 1.2e-24 86.7 0.6 1.2e-24 86.7 0.6 2.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) PH PF00169.29 VBB25403.1 - 1.2e-07 32.2 1.0 3.8e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 PH domain NAD_kinase PF01513.21 VBB25405.1 - 3.9e-11 42.7 0.0 8.4e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 ATP-NAD kinase Peptidase_S51 PF03575.17 VBB25405.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DAGK_cat PF00781.24 VBB25405.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF4447 PF14590.6 VBB25405.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) DUF4350 PF14258.6 VBB25405.1 - 0.094 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Kinesin PF00225.23 VBB25406.1 - 9.4e-113 376.5 0.0 2.6e-112 375.0 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 VBB25406.1 - 8.9e-26 90.6 0.4 8.2e-25 87.5 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding HAUS-augmin3 PF14932.6 VBB25406.1 - 0.27 10.8 24.9 0.088 12.4 20.6 2.2 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Kinesin_assoc PF16183.5 VBB25406.1 - 0.53 10.4 21.6 0.065 13.4 12.2 3.9 4 1 0 4 4 4 0 Kinesin-associated AAA_22 PF13401.6 VBB25406.1 - 3.9 7.7 7.1 4.6 7.5 0.0 3.5 3 1 0 3 3 3 0 AAA domain ELO PF01151.18 VBB25407.1 - 6.4e-64 215.9 23.3 7.4e-64 215.7 23.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCM2_C PF16545.5 VBB25408.1 - 1.6e-09 38.2 0.1 4.9e-09 36.6 0.1 1.7 2 0 0 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology Pkinase PF00069.25 VBB25409.1 - 7e-67 225.6 0.0 8.2e-66 222.1 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain cNMP_binding PF00027.29 VBB25409.1 - 1e-39 134.5 0.5 8.6e-20 70.6 0.1 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 VBB25409.1 - 1.6e-31 109.6 0.0 5.3e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Fib_alpha PF08702.10 VBB25409.1 - 0.00062 20.0 5.7 0.0016 18.7 5.7 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Spc29 PF17082.5 VBB25409.1 - 0.0035 17.2 2.1 0.0058 16.5 2.1 1.4 1 0 0 1 1 1 1 Spindle Pole Component 29 Vps54_N PF10475.9 VBB25409.1 - 0.004 16.5 4.2 0.0068 15.7 4.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex FliD_N PF02465.18 VBB25409.1 - 0.0077 16.9 5.2 0.027 15.2 5.4 1.9 2 0 0 2 2 1 1 Flagellar hook-associated protein 2 N-terminus DUF16 PF01519.16 VBB25409.1 - 0.0078 16.7 6.5 0.021 15.3 6.5 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF16 TSC22 PF01166.18 VBB25409.1 - 0.012 15.9 2.9 0.077 13.3 0.8 3.1 3 0 0 3 3 2 0 TSC-22/dip/bun family DUF641 PF04859.12 VBB25409.1 - 0.013 15.9 4.6 0.013 15.9 4.6 2.0 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 VBB25409.1 - 0.015 15.1 4.0 0.059 13.1 4.0 2.1 1 0 0 1 1 1 0 Septum formation initiator JAKMIP_CC3 PF16034.5 VBB25409.1 - 0.04 13.9 7.8 0.43 10.5 6.4 2.5 2 0 0 2 2 2 0 JAKMIP CC3 domain YkyA PF10368.9 VBB25409.1 - 0.065 12.9 4.6 0.12 12.0 4.6 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein V_ATPase_I PF01496.19 VBB25409.1 - 0.07 11.0 1.5 0.091 10.7 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCPsignal PF00015.21 VBB25409.1 - 0.092 12.5 3.1 0.18 11.6 3.1 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 VBB25409.1 - 0.11 12.6 1.4 0.22 11.5 1.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 VBB25409.1 - 0.11 12.6 13.4 9.1 6.3 12.2 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 VBB25409.1 - 0.14 12.8 4.6 1.7 9.3 5.8 2.3 2 0 0 2 2 1 0 Initiation control protein YabA SlyX PF04102.12 VBB25409.1 - 0.19 12.4 5.3 0.6 10.8 5.3 2.0 1 0 0 1 1 1 0 SlyX Atg14 PF10186.9 VBB25409.1 - 0.23 10.5 10.1 0.36 9.9 10.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG5 PF10392.9 VBB25409.1 - 0.23 11.6 5.3 0.49 10.6 5.3 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3552 PF12072.8 VBB25409.1 - 0.25 10.7 16.7 0.38 10.2 16.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) USP8_interact PF08941.10 VBB25409.1 - 0.34 10.7 3.2 0.62 9.8 3.2 1.5 1 0 0 1 1 1 0 USP8 interacting Allexi_40kDa PF05549.11 VBB25409.1 - 0.37 10.3 2.4 0.76 9.2 2.4 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein CCDC106 PF15794.5 VBB25409.1 - 0.48 10.1 8.6 0.75 9.5 8.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ADIP PF11559.8 VBB25409.1 - 0.52 10.4 10.6 1.2 9.2 10.6 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fzo_mitofusin PF04799.13 VBB25409.1 - 0.52 9.8 3.9 1.1 8.8 3.9 1.4 1 0 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.11 VBB25409.1 - 0.73 10.3 4.9 1.1 9.7 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 VBB25409.1 - 0.81 9.7 10.6 0.94 9.5 3.2 2.6 1 1 1 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 VBB25409.1 - 0.86 9.9 5.2 1.2 9.5 3.8 1.9 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.9 VBB25409.1 - 0.94 9.8 8.1 3.9 7.8 8.1 2.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Tho2 PF11262.8 VBB25409.1 - 1.1 8.4 5.2 1.6 7.9 4.2 1.7 2 0 0 2 2 1 0 Transcription factor/nuclear export subunit protein 2 DUF4164 PF13747.6 VBB25409.1 - 1.2 9.5 8.1 0.43 10.9 4.8 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) FemAB PF02388.16 VBB25409.1 - 1.2 7.9 4.1 1.6 7.5 3.2 1.6 2 0 0 2 2 1 0 FemAB family ATG16 PF08614.11 VBB25409.1 - 1.4 9.1 14.7 0.79 9.9 12.3 1.8 1 1 1 2 2 1 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 VBB25409.1 - 1.5 9.5 13.6 0.92 10.2 11.1 1.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mod_r PF07200.13 VBB25409.1 - 1.6 8.8 10.4 8 6.6 10.9 1.9 2 1 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein zf-C4H2 PF10146.9 VBB25409.1 - 1.7 8.9 7.6 3.1 8.1 7.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein TMPIT PF07851.13 VBB25409.1 - 1.9 7.6 5.0 3.6 6.8 5.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 VBB25409.1 - 2.3 8.0 8.6 3.8 7.3 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 VBB25409.1 - 2.4 7.4 11.2 4.1 6.7 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 VBB25409.1 - 3.9 7.6 5.8 5.1 7.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 VBB25409.1 - 4.2 7.7 9.7 3.3 8.0 7.2 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF1043 PF06295.12 VBB25409.1 - 4.5 7.3 9.8 12 5.9 9.3 1.9 1 1 1 2 2 1 0 Protein of unknown function (DUF1043) AAA_13 PF13166.6 VBB25409.1 - 7.4 5.1 11.1 10 4.6 11.1 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.24 VBB25410.1 - 6.6e-45 153.4 0.1 9.7e-45 152.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SLX9 PF15341.6 VBB25410.1 - 0.19 12.2 3.1 0.36 11.2 3.1 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 She9_MDM33 PF05546.11 VBB25411.1 - 1.9e-05 24.5 2.5 4.3e-05 23.4 2.5 1.6 1 0 0 1 1 1 1 She9 / Mdm33 family KELK PF15796.5 VBB25411.1 - 0.0034 17.8 3.4 0.0034 17.8 3.4 3.0 3 0 0 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase KH_8 PF17903.1 VBB25411.1 - 0.029 14.4 0.2 0.078 13.1 0.2 1.7 1 0 0 1 1 1 0 Krr1 KH1 domain SbsC_C PF18058.1 VBB25411.1 - 0.051 13.8 0.8 0.44 10.8 0.1 2.5 2 0 0 2 2 2 0 SbsC C-terminal domain Hemerythrin PF01814.23 VBB25411.1 - 0.11 13.1 3.7 0.16 12.6 1.0 2.4 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain HAUS-augmin3 PF14932.6 VBB25411.1 - 0.51 9.9 9.9 0.042 13.4 3.2 2.5 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 Vinculin PF01044.19 VBB25412.1 - 0 1432.5 5.2 0 1432.2 5.2 1.0 1 0 0 1 1 1 1 Vinculin family I_LWEQ PF01608.17 VBB25412.1 - 0.017 15.4 25.5 0.12 12.7 0.1 6.2 5 2 1 6 6 6 0 I/LWEQ domain Clusterin PF01093.17 VBB25412.1 - 0.027 13.5 0.0 0.071 12.1 0.0 1.7 1 0 0 1 1 1 0 Clusterin Abi_C PF14355.6 VBB25412.1 - 0.061 13.4 0.3 4.6 7.4 0.0 4.2 4 1 1 5 5 5 0 Abortive infection C-terminus DUF1759 PF03564.15 VBB25412.1 - 0.22 11.4 0.6 1.9 8.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF3140 PF11338.8 VBB25412.1 - 0.33 11.4 4.2 12 6.4 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3140) DUF883 PF05957.13 VBB25412.1 - 1.9 9.2 8.5 2.2 8.9 0.1 4.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF615 PF04751.14 VBB25412.1 - 3.1 7.8 6.3 2.8 7.9 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF615) COG2 PF06148.11 VBB25412.1 - 7 6.7 9.3 4.5 7.4 0.2 4.2 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TFIID-18kDa PF02269.16 VBB25413.1 - 1.8e-32 111.2 0.7 2.3e-32 110.9 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit EF-1_beta_acid PF10587.9 VBB25413.1 - 0.0048 17.3 3.3 0.0048 17.3 3.3 2.3 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Telomerase_RBD PF12009.8 VBB25414.1 - 4.7e-09 36.5 1.4 2.1e-08 34.3 0.9 2.5 2 1 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 VBB25414.1 - 2e-06 27.5 0.3 0.00037 20.1 0.0 3.2 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) PGM_PMM_I PF02878.16 VBB25416.1 - 1.4e-14 54.0 0.0 3.7e-08 33.2 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 VBB25416.1 - 1.3e-10 41.3 0.0 3.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 VBB25416.1 - 0.00012 22.6 0.0 0.0013 19.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 VBB25416.1 - 0.028 14.6 0.0 0.078 13.2 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PUF PF00806.19 VBB25417.1 - 0.00051 19.6 9.3 2 8.3 0.0 6.2 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat RNase_Zc3h12a PF11977.8 VBB25417.1 - 0.019 14.7 0.1 0.065 13.0 0.1 1.9 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Caveolin PF01146.17 VBB25417.1 - 0.039 13.9 0.4 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 Caveolin Ras PF00071.22 VBB25418.1 - 6.4e-52 175.4 0.0 7.5e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB25418.1 - 4.2e-21 75.4 0.0 6.7e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 VBB25418.1 - 3.8e-07 29.8 0.2 6.4e-06 25.8 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 VBB25418.1 - 4.7e-07 29.4 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB25418.1 - 2.5e-06 27.5 0.0 0.021 14.7 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 VBB25418.1 - 0.00014 22.0 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB25418.1 - 0.00085 18.9 0.1 0.0033 16.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 VBB25418.1 - 0.029 13.7 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 Septin Hpr_kinase_C PF07475.12 VBB25418.1 - 0.035 13.6 0.0 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ATP_bind_1 PF03029.17 VBB25418.1 - 0.11 12.2 0.1 2.2 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 VBB25418.1 - 0.12 12.8 0.1 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Inhibitor_I29 PF08246.12 VBB25420.1 - 5.2e-07 30.0 0.2 9.2e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DM PF00751.18 VBB25422.1 - 1.9e-14 53.2 14.1 2.6e-14 52.8 14.1 1.2 1 0 0 1 1 1 1 DM DNA binding domain SR-25 PF10500.9 VBB25423.1 - 0.45 10.1 16.0 0.55 9.8 16.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DM PF00751.18 VBB25424.1 - 2.1e-19 69.1 12.0 4e-19 68.2 12.0 1.5 1 0 0 1 1 1 1 DM DNA binding domain DDHD PF02862.17 VBB25424.1 - 0.0024 18.1 4.9 0.004 17.4 4.9 1.4 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 VBB25424.1 - 0.0028 17.7 36.5 0.0039 17.3 36.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 VBB25424.1 - 0.02 14.0 19.7 0.039 13.1 19.7 1.5 1 0 0 1 1 1 0 SprA-related family EOS1 PF12326.8 VBB25424.1 - 0.022 14.7 0.8 0.036 14.0 0.8 1.4 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 VBB25424.1 - 0.04 12.9 10.5 0.054 12.5 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 VBB25424.1 - 0.041 12.6 8.0 0.059 12.1 8.0 1.3 1 0 0 1 1 1 0 Presenilin MMR1 PF08505.10 VBB25424.1 - 0.059 13.7 15.2 0.091 13.0 15.2 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2126 PF09899.9 VBB25424.1 - 0.095 10.8 6.1 0.14 10.2 6.1 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) V_ATPase_I PF01496.19 VBB25424.1 - 0.1 10.5 8.7 0.018 13.0 5.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UPF0560 PF10577.9 VBB25424.1 - 0.1 11.1 17.3 0.19 10.2 17.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4746 PF15928.5 VBB25424.1 - 0.12 11.8 4.2 0.18 11.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Activator_LAG-3 PF11498.8 VBB25424.1 - 0.12 11.3 40.8 0.19 10.7 40.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FHIPEP PF00771.20 VBB25424.1 - 0.14 10.6 5.8 0.2 10.1 5.8 1.2 1 0 0 1 1 1 0 FHIPEP family DUF2722 PF10846.8 VBB25424.1 - 0.16 10.9 26.9 0.37 9.7 26.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIP PF07454.11 VBB25424.1 - 0.19 11.2 9.3 0.31 10.5 9.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 VBB25424.1 - 0.25 11.3 7.0 0.51 10.4 7.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EPL1 PF10513.9 VBB25424.1 - 0.28 11.6 10.3 0.12 12.8 7.9 1.6 2 0 0 2 2 1 0 Enhancer of polycomb-like PepSY_TM PF03929.16 VBB25424.1 - 0.31 10.6 4.2 0.63 9.7 4.2 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Tim54 PF11711.8 VBB25424.1 - 0.33 9.7 7.7 0.49 9.1 7.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 VBB25424.1 - 0.37 9.0 23.2 0.58 8.4 23.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CMV_1a PF12467.8 VBB25424.1 - 0.37 11.1 4.5 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Pinin_SDK_memA PF04696.13 VBB25424.1 - 0.48 10.5 27.9 1.2 9.2 25.6 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Ctr PF04145.15 VBB25424.1 - 0.66 10.6 6.7 1.9 9.1 6.7 1.7 1 0 0 1 1 1 0 Ctr copper transporter family Pannexin_like PF12534.8 VBB25424.1 - 0.69 8.9 10.6 1.2 8.1 10.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AIF_C PF14721.6 VBB25424.1 - 0.75 10.2 6.2 1.7 9.0 6.2 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TERB2 PF15101.6 VBB25424.1 - 0.78 9.8 16.6 1.9 8.5 16.6 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 VBB25424.1 - 0.79 9.4 5.9 1.3 8.7 5.9 1.3 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 VBB25424.1 - 1.2 9.3 14.1 0.3 11.2 9.7 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pal1 PF08316.11 VBB25424.1 - 1.2 9.8 7.6 2.8 8.7 7.6 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein Serinc PF03348.15 VBB25424.1 - 1.4 7.8 5.3 2.1 7.2 5.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 VBB25424.1 - 1.4 9.9 13.3 5.3 8.1 13.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 VBB25424.1 - 1.5 8.4 42.3 1.5 8.4 40.1 2.0 2 0 0 2 2 2 0 Spt20 family DUF4175 PF13779.6 VBB25424.1 - 1.5 6.6 30.5 2.1 6.1 30.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CLN3 PF02487.17 VBB25424.1 - 1.9 7.4 7.4 2.9 6.9 7.4 1.2 1 0 0 1 1 1 0 CLN3 protein DUF2828 PF11443.8 VBB25424.1 - 3.2 5.7 11.5 4.6 5.2 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Coilin_N PF15862.5 VBB25424.1 - 3.4 7.5 13.1 0.53 10.1 9.2 1.6 2 0 0 2 2 1 0 Coilin N-terminus RED_N PF07808.13 VBB25424.1 - 3.5 7.2 14.9 8 6.0 14.9 1.6 1 0 0 1 1 1 0 RED-like protein N-terminal region Gti1_Pac2 PF09729.9 VBB25424.1 - 4.5 7.3 9.1 9.5 6.3 9.1 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Band_3_cyto PF07565.13 VBB25424.1 - 4.8 6.9 13.9 1.6 8.5 11.0 1.5 2 0 0 2 2 1 0 Band 3 cytoplasmic domain MTP18 PF10558.9 VBB25424.1 - 5.7 6.9 8.7 12 5.9 8.7 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) FAM176 PF14851.6 VBB25424.1 - 5.7 6.6 7.0 11 5.7 7.0 1.4 1 0 0 1 1 1 0 FAM176 family Orf78 PF06024.12 VBB25424.1 - 5.9 7.2 6.5 14 6.0 6.5 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF3439 PF11921.8 VBB25424.1 - 7.7 6.5 13.2 17 5.4 4.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3439) DUF3492 PF11997.8 VBB25424.1 - 7.7 6.2 7.6 13 5.4 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) BRF1 PF07741.13 VBB25424.1 - 7.9 6.9 11.1 19 5.7 11.1 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4770 PF15994.5 VBB25424.1 - 8 6.7 18.6 0.8 9.9 12.4 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4770) ALMT PF11744.8 VBB25424.1 - 8.1 5.2 9.1 13 4.5 9.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EMC3_TMCO1 PF01956.16 VBB25424.1 - 8.6 6.1 9.6 16 5.2 8.6 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Membralin PF09746.9 VBB25424.1 - 8.8 5.3 9.8 14 4.6 9.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein Ground-like PF04155.18 VBB25425.1 - 9.7e-19 67.8 2.5 1.5e-18 67.2 2.5 1.3 1 0 0 1 1 1 1 Ground-like domain MgtE PF01769.16 VBB25426.1 - 2.7e-35 121.5 32.2 1.9e-21 76.7 6.7 3.4 3 0 0 3 3 3 2 Divalent cation transporter Ammonium_transp PF00909.21 VBB25427.1 - 5.3e-66 223.0 21.0 6.9e-66 222.6 21.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase_Tyr PF07714.17 VBB25428.1 - 9.4e-76 254.5 0.0 1.5e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB25428.1 - 1.9e-42 145.5 0.0 3.6e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane PF01061.24 VBB25428.1 - 4.1e-21 75.4 30.2 3.4e-17 62.6 12.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 VBB25428.1 - 1.4e-15 58.1 0.0 4.2e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SH2 PF00017.24 VBB25428.1 - 3.1e-10 40.0 0.0 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Kelch_1 PF01344.25 VBB25429.1 - 8e-42 140.6 9.1 4.5e-10 39.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 VBB25429.1 - 1.7e-15 56.7 1.1 0.013 15.7 0.0 5.6 3 1 2 5 5 5 4 Kelch motif Kelch_4 PF13418.6 VBB25429.1 - 2e-11 43.7 2.3 0.01 15.8 0.0 5.2 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 VBB25429.1 - 1e-09 38.4 4.2 0.14 12.5 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 VBB25429.1 - 2e-08 33.9 2.9 0.86 9.7 0.0 5.6 5 0 0 5 5 5 3 Kelch motif BACK PF07707.15 VBB25429.1 - 0.00033 20.7 0.1 0.00077 19.5 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 VBB25429.1 - 0.092 12.8 12.3 4.4 7.4 0.0 5.5 6 0 0 6 6 6 0 Kelch motif RRM_7 PF16367.5 VBB25431.1 - 9.5e-39 131.4 0.0 1.2e-36 124.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif CEBP_ZZ PF16366.5 VBB25431.1 - 5.6e-20 71.3 9.6 5.6e-20 71.3 9.6 2.1 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 VBB25431.1 - 4.6e-13 48.8 0.0 2.5e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.19 VBB25432.1 - 8.2e-06 26.1 1.8 1.7e-05 25.2 1.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB25432.1 - 0.0017 18.9 2.0 0.0036 17.8 2.0 1.5 1 0 0 1 1 1 1 HMG-box domain Maelstrom PF13017.6 VBB25432.1 - 0.02 14.6 1.4 0.047 13.4 1.4 1.7 1 1 0 1 1 1 0 piRNA pathway germ-plasm component Prolamin_like PF05617.11 VBB25432.1 - 0.21 11.8 3.9 3.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Prolamin-like CLTH PF10607.9 VBB25433.1 - 2.7e-28 98.7 1.1 3.6e-28 98.3 1.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 VBB25433.1 - 0.00064 19.6 0.1 0.0017 18.3 0.1 1.7 1 0 0 1 1 1 1 LisH DUF1441 PF07278.11 VBB25433.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) Cofilin_ADF PF00241.20 VBB25434.1 - 1.1e-55 186.6 3.5 9.4e-31 106.1 0.3 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF3378 PF11858.8 VBB25434.1 - 0.081 13.0 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) Pro_isomerase PF00160.21 VBB25435.1 - 1.5e-37 129.3 0.0 1.8e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LBP_BPI_CETP PF01273.25 VBB25437.1 - 1.9e-12 47.1 0.3 3.9e-12 46.1 0.3 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 VBB25437.1 - 3.1e-07 30.1 0.0 2.3e-05 24.0 0.0 3.3 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Phage_TAC_10 PF10963.8 VBB25438.1 - 0.0035 17.5 0.0 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 Phage tail assembly chaperone zf-C4_Topoisom PF01396.19 VBB25438.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Clat_adaptor_s PF01217.20 VBB25439.1 - 1.1e-60 203.6 8.2 1.2e-60 203.5 8.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4649 PF15507.6 VBB25439.1 - 0.014 15.3 1.0 0.019 14.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) Acetyltransf_10 PF13673.7 VBB25440.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 VBB25440.1 - 0.039 14.4 0.1 0.07 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Collagen PF01391.18 VBB25441.1 - 8.4e-05 22.2 12.2 0.00011 21.9 12.2 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) COX6C PF02937.15 VBB25441.1 - 0.31 11.2 0.5 0.31 11.2 0.5 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc CytochromB561_N PF09786.9 VBB25442.1 - 0.00031 19.9 4.0 0.00046 19.3 4.0 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal SARAF PF06682.12 VBB25442.1 - 0.0011 18.7 1.9 0.0015 18.2 1.9 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TssO PF17561.2 VBB25442.1 - 0.0042 17.2 5.2 0.0042 17.2 5.2 2.7 2 1 1 3 3 3 1 Type VI secretion system, TssO Wzy_C PF04932.15 VBB25442.1 - 0.008 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 O-Antigen ligase SID-1_RNA_chan PF13965.6 VBB25442.1 - 0.011 14.2 8.1 0.015 13.8 8.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ATP-synt_B PF00430.18 VBB25442.1 - 0.012 15.7 1.4 0.012 15.7 1.4 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) CLN3 PF02487.17 VBB25442.1 - 0.013 14.6 5.6 0.022 13.9 5.6 1.4 1 0 0 1 1 1 0 CLN3 protein Sigma_reg_N PF13800.6 VBB25442.1 - 0.019 15.2 0.4 0.019 15.2 0.4 2.0 2 0 0 2 2 1 0 Sigma factor regulator N-terminal ABC2_membrane_2 PF12679.7 VBB25442.1 - 0.023 14.0 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein 7TM_GPCR_Srv PF10323.9 VBB25442.1 - 0.024 14.0 1.0 0.044 13.2 1.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF3169 PF11368.8 VBB25442.1 - 0.028 13.9 0.6 0.028 13.9 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) COX14 PF14880.6 VBB25442.1 - 0.035 13.9 1.3 0.035 13.9 1.3 2.6 3 0 0 3 3 2 0 Cytochrome oxidase c assembly DUF4407 PF14362.6 VBB25442.1 - 0.049 13.0 11.4 0.076 12.4 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DcuC PF03606.15 VBB25442.1 - 0.065 11.7 1.8 0.1 11.0 1.8 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier PepSY_TM PF03929.16 VBB25442.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region GRIM-19 PF06212.12 VBB25442.1 - 0.1 12.5 0.4 0.1 12.5 0.4 2.4 2 0 0 2 2 2 0 GRIM-19 protein MFS_Mycoplasma PF07672.13 VBB25442.1 - 0.11 11.8 1.3 0.18 11.0 1.3 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter Shisa PF13908.6 VBB25442.1 - 0.11 12.7 5.3 0.17 12.1 4.8 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator NicO PF03824.16 VBB25442.1 - 0.13 11.5 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Mem_trans PF03547.18 VBB25442.1 - 0.14 10.5 6.5 0.18 10.2 6.5 1.1 1 0 0 1 1 1 0 Membrane transport protein CD20 PF04103.15 VBB25442.1 - 0.22 11.6 0.4 0.49 10.5 0.1 1.7 1 1 1 2 2 2 0 CD20-like family Phage_holin_2_1 PF04971.12 VBB25442.1 - 0.28 11.2 1.7 0.5 10.4 1.7 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S Zip PF02535.22 VBB25442.1 - 0.3 10.3 3.1 0.43 9.8 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 VBB25442.1 - 0.31 9.8 11.5 0.51 9.1 11.5 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein MLANA PF14991.6 VBB25442.1 - 0.68 10.2 5.6 0.22 11.8 1.1 2.3 1 1 1 2 2 2 0 Protein melan-A OAD_gamma PF04277.13 VBB25442.1 - 0.71 10.5 2.6 8 7.1 2.6 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4834 PF16118.5 VBB25442.1 - 2.3 9.2 20.1 99 4.0 20.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) HemX PF04375.14 VBB25442.1 - 2.9 7.1 18.0 6.7 5.9 18.0 1.6 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OATP PF03137.20 VBB25442.1 - 3.3 5.9 8.1 7.4 4.7 8.1 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Protocadherin PF08374.11 VBB25442.1 - 5.5 6.9 12.1 11 5.9 12.1 1.6 1 1 0 1 1 1 0 Protocadherin Nucleoside_tran PF01733.18 VBB25442.1 - 6.3 6.1 8.3 18 4.6 8.3 1.9 1 1 0 1 1 1 0 Nucleoside transporter Kei1 PF08552.11 VBB25442.1 - 6.3 6.6 6.4 13 5.6 6.4 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 EphA2_TM PF14575.6 VBB25442.1 - 8.3 7.4 9.3 48 4.9 9.3 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adap_comp_sub PF00928.21 VBB25443.1 - 5.7e-80 268.5 0.1 7.4e-80 268.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 VBB25443.1 - 6.3e-07 29.4 0.2 1.2e-06 28.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain mTERF PF02536.14 VBB25444.1 - 2.2e-09 36.7 1.6 6.3e-06 25.3 0.3 2.3 1 1 1 2 2 2 2 mTERF CCDC66 PF15236.6 VBB25444.1 - 0.32 10.8 3.1 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 zf-H2C2_2 PF13465.6 VBB25446.1 - 2.3e-14 53.1 24.6 3.6e-07 30.3 0.4 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 VBB25446.1 - 1.7e-09 37.6 33.3 0.00024 21.4 0.8 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB25446.1 - 1.9e-06 28.2 40.9 0.0026 18.4 0.8 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger PyrI_C PF02748.15 VBB25446.1 - 0.0021 17.9 5.7 0.68 9.9 0.0 3.7 4 0 0 4 4 4 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 VBB25446.1 - 0.013 15.8 11.0 5.1 7.5 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB25446.1 - 0.092 12.8 0.1 0.092 12.8 0.1 4.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 VBB25446.1 - 0.19 12.1 10.2 1.2 9.6 0.8 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 VBB25446.1 - 0.42 11.4 8.2 5.3 7.9 1.4 2.5 2 0 0 2 2 2 0 zinc-ribbon family zf-C2H2_11 PF16622.5 VBB25446.1 - 7.5 6.4 15.4 0.44 10.3 1.9 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type FYVE PF01363.21 VBB25446.1 - 10 6.4 14.7 9.3e+02 0.1 14.6 2.9 1 1 0 1 1 1 0 FYVE zinc finger HLH PF00010.26 VBB25447.1 - 1.3e-17 63.5 0.7 1.3e-17 63.5 0.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Stathmin PF00836.19 VBB25447.1 - 0.13 12.2 3.9 0.16 11.9 3.9 1.3 1 1 0 1 1 1 0 Stathmin family MFS_1 PF07690.16 VBB25448.1 - 6.5e-27 94.4 42.0 6.5e-27 94.4 42.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB25448.1 - 9.8e-07 28.0 35.6 8.9e-05 21.5 9.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 VBB25448.1 - 0.0011 17.3 9.4 0.0011 17.3 9.4 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FKBP_C PF00254.28 VBB25449.1 - 3.7e-13 49.6 0.0 1.8e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 VBB25449.1 - 4.2e-08 32.2 3.8 1.5e-05 24.2 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 VBB25449.1 - 1.7e-06 27.8 2.7 0.0027 17.5 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB25449.1 - 2.6e-06 26.7 8.4 0.00048 19.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 VBB25449.1 - 1.5e-05 25.3 1.9 0.0051 17.2 1.0 3.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB25449.1 - 2.5e-05 23.9 3.7 0.0017 18.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain DUF3872 PF12988.7 VBB25449.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3872) SPARC_Ca_bdg PF10591.9 VBB25449.1 - 0.082 13.2 0.2 8.6 6.7 0.2 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 VBB25449.1 - 0.19 12.0 1.4 10 6.4 0.0 2.9 3 0 0 3 3 3 0 Dockerin type I domain VCBS PF13517.6 VBB25449.1 - 0.58 10.8 2.3 18 6.0 0.8 2.7 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2371 PF10177.9 VBB25450.1 - 4.3e-12 46.4 0.4 1.2e-11 45.0 0.4 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) TMEM171 PF15471.6 VBB25450.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein family 171 Neurensin PF14927.6 VBB25450.1 - 0.043 13.5 0.9 0.095 12.4 0.9 1.5 1 1 0 1 1 1 0 Neurensin PLAT PF01477.23 VBB25451.1 - 6.3e-31 107.4 0.9 3.5e-13 50.1 0.1 5.1 5 0 0 5 5 5 4 PLAT/LH2 domain DCX PF03607.17 VBB25451.1 - 7.1e-25 86.9 0.0 1.2e-16 60.6 0.0 2.6 2 0 0 2 2 2 2 Doublecortin CDC45 PF02724.14 VBB25451.1 - 0.54 8.5 9.0 0.79 7.9 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Tox-ODYAM1 PF15642.6 VBB25451.1 - 3.3 6.6 7.5 5.4 5.9 7.5 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Forkhead PF00250.18 VBB25452.1 - 1.7e-33 114.7 0.0 1.7e-33 114.7 0.0 1.8 2 0 0 2 2 2 1 Forkhead domain 7tm_1 PF00001.21 VBB25453.1 - 3.7e-31 108.4 20.3 6e-31 107.7 20.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 VBB25453.1 - 0.00014 21.4 21.1 0.00033 20.1 21.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv BRCC36_C PF18110.1 VBB25453.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain bZIP_2 PF07716.15 VBB25454.1 - 2.3e-14 53.2 13.7 3.8e-14 52.5 13.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 VBB25454.1 - 0.0001 22.3 9.1 0.00021 21.3 9.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SR-25 PF10500.9 VBB25454.1 - 0.0015 18.2 7.0 0.0015 18.2 7.0 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Cas_Csy4 PF09618.10 VBB25454.1 - 0.02 15.0 1.7 0.035 14.3 1.7 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) bZIP_Maf PF03131.17 VBB25454.1 - 0.76 10.3 12.1 0.052 14.1 7.0 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Transket_pyr PF02779.24 VBB25455.1 - 1.3e-41 142.3 0.0 1.7e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 VBB25455.1 - 3e-35 120.8 0.0 4.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain NTP_transf_7 PF07984.12 VBB25456.1 - 2.8e-142 473.7 0.1 3.3e-142 473.5 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase FAT PF02259.23 VBB25457.1 - 1.8e-25 89.9 5.3 1.8e-25 89.9 5.3 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 VBB25457.1 - 1.9e-06 27.9 0.3 5.3e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_1 PF00515.28 VBB25457.1 - 0.0019 18.0 0.6 0.69 9.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB25457.1 - 0.0069 16.4 1.6 0.34 11.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ARL2_Bind_BART PF11527.8 VBB25457.1 - 0.0094 16.0 6.3 1 9.5 0.9 4.4 3 0 0 3 3 3 1 The ARF-like 2 binding protein BART Mad3_BUB1_I PF08311.12 VBB25457.1 - 0.12 12.4 2.1 28 4.7 0.0 4.5 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 HEAT_EZ PF13513.6 VBB25457.1 - 0.14 12.7 0.3 3 8.4 0.0 3.4 2 0 0 2 2 2 0 HEAT-like repeat SapB_2 PF03489.17 VBB25457.1 - 0.38 10.9 2.6 12 6.1 0.3 3.5 2 0 0 2 2 2 0 Saposin-like type B, region 2 Complex1_LYR PF05347.15 VBB25458.1 - 5.4e-15 55.2 1.2 7.4e-15 54.7 1.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 VBB25458.1 - 0.00024 21.8 0.3 0.0003 21.5 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 VBB25458.1 - 0.00071 20.1 0.0 0.00081 19.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like SKICH PF17751.1 VBB25458.1 - 0.043 14.4 0.1 0.051 14.1 0.1 1.2 1 1 0 1 1 1 0 SKICH domain YfiO PF13525.6 VBB25458.1 - 0.053 13.2 0.1 0.062 13.0 0.1 1.0 1 0 0 1 1 1 0 Outer membrane lipoprotein Band_7_1 PF13421.6 VBB25458.1 - 0.088 12.5 0.0 0.094 12.4 0.0 1.0 1 0 0 1 1 1 0 SPFH domain-Band 7 family MAT1 PF06391.13 VBB25459.1 - 2.5e-42 145.1 12.6 3.2e-42 144.7 12.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 VBB25459.1 - 1.9e-08 34.1 9.2 1.9e-08 34.1 9.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB25459.1 - 1.8e-05 24.5 7.7 3.5e-05 23.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB25459.1 - 9.1e-05 22.7 6.5 0.00018 21.8 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 VBB25459.1 - 0.00015 21.5 10.4 0.00052 19.8 10.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB25459.1 - 0.00024 21.0 7.8 0.00057 19.8 7.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB25459.1 - 0.0094 16.0 7.4 0.021 14.8 7.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Dict-STAT-coil PF09267.10 VBB25459.1 - 0.029 14.8 0.6 0.084 13.3 0.5 1.8 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Prok-RING_4 PF14447.6 VBB25459.1 - 0.035 14.0 7.4 0.11 12.4 7.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 VBB25459.1 - 0.037 13.9 12.6 0.21 11.5 12.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB25459.1 - 0.078 13.2 6.2 0.24 11.6 6.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 VBB25459.1 - 0.13 12.4 7.4 2 8.6 7.4 2.4 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 VBB25459.1 - 0.56 10.1 12.3 6 6.7 12.3 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Streptin-Immun PF11083.8 VBB25459.1 - 0.61 10.5 8.0 0.081 13.3 2.1 2.4 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein VP_N-CPKC PF11475.8 VBB25459.1 - 3.4 7.7 9.4 0.78 9.7 1.0 2.9 3 0 0 3 3 2 0 Virion protein N terminal domain Xpo1 PF08389.12 VBB25460.1 - 1.7e-24 86.5 1.2 1.7e-24 86.5 1.2 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 VBB25460.1 - 0.0052 16.7 0.1 0.021 14.7 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Picorna_P3A PF06363.11 VBB25460.1 - 0.031 14.1 0.0 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 Picornaviridae P3A protein Vac14_Fab1_bd PF12755.7 VBB25460.1 - 0.11 13.1 0.2 1 10.0 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region EF-hand_6 PF13405.6 VBB25461.1 - 2.3e-19 67.6 5.9 0.00029 20.5 0.1 5.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 VBB25461.1 - 4.1e-19 66.6 11.8 2.3e-05 23.6 0.4 5.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 VBB25461.1 - 1.7e-16 60.4 9.5 1.4e-08 35.1 3.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB25461.1 - 1.7e-10 39.9 10.5 0.00076 18.9 0.1 5.5 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 VBB25461.1 - 1.7e-08 34.2 11.5 5.7e-05 22.9 2.9 4.4 4 1 1 5 5 5 3 EF-hand domain pair p25-alpha PF05517.12 VBB25461.1 - 5.2e-05 23.4 2.6 0.001 19.2 0.5 2.3 1 1 1 2 2 2 1 p25-alpha EF-hand_14 PF17959.1 VBB25461.1 - 0.02 15.3 0.1 0.055 13.8 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 VBB25461.1 - 0.027 14.4 0.7 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.7 VBB25461.1 - 0.16 11.9 0.6 2 8.4 0.1 2.4 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 VBB25462.1 - 0.00025 20.4 2.3 0.00059 19.2 2.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 VBB25462.1 - 0.0008 19.2 1.3 0.0016 18.2 1.3 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 VBB25462.1 - 0.0017 18.8 2.5 0.0021 18.5 1.6 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 VBB25462.1 - 0.0018 17.7 1.0 0.005 16.3 0.6 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 VBB25462.1 - 0.0023 17.7 2.0 0.0055 16.5 2.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF_assoc_2 PF08356.12 VBB25462.1 - 0.0065 16.4 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 EF hand associated 7tm_1 PF00001.21 VBB25464.1 - 8.3e-17 61.4 5.2 1.4e-16 60.7 5.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CUT PF02376.15 VBB25465.1 - 1.2e-30 105.5 0.0 2.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 VBB25465.1 - 1.1e-10 41.2 2.4 1.1e-10 41.2 2.4 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB25465.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ig_3 PF13927.6 VBB25466.1 - 0.00061 20.3 0.1 0.0026 18.3 0.1 2.2 1 0 0 1 1 1 1 Immunoglobulin domain DUF3877 PF12993.7 VBB25466.1 - 0.0017 18.3 0.3 0.025 14.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) Ig_2 PF13895.6 VBB25466.1 - 0.0035 17.6 0.0 0.016 15.6 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain DUF2884 PF11101.8 VBB25466.1 - 0.0071 15.9 0.8 0.019 14.5 0.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2884) DUF4407 PF14362.6 VBB25466.1 - 0.041 13.2 3.4 0.075 12.4 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 VBB25466.1 - 0.18 12.0 0.3 1.1 9.5 0.1 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Holin_BhlA PF10960.8 VBB25466.1 - 1.9 8.5 4.2 21 5.2 0.5 3.4 3 0 0 3 3 3 0 BhlA holin family BLOC1_2 PF10046.9 VBB25466.1 - 7.8 6.9 11.2 2 8.8 1.0 3.7 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAN_1 PF00024.26 VBB25467.1 - 3.1e-15 55.9 39.5 0.0036 17.2 8.4 5.7 5 0 0 5 5 5 5 PAN domain PAN_3 PF08277.12 VBB25467.1 - 0.003 17.3 0.7 0.003 17.3 0.7 6.2 6 0 0 6 6 6 3 PAN-like domain PLDc_3 PF13918.6 VBB25468.1 - 1.3e-34 119.4 0.1 2.7e-34 118.3 0.1 1.6 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 VBB25468.1 - 1.5e-22 79.9 0.3 3e-08 33.6 0.2 3.4 2 1 1 3 3 3 3 PLD-like domain PLDc PF00614.22 VBB25468.1 - 9e-11 41.5 3.5 3e-09 36.7 0.8 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Integrase_H2C2 PF17921.1 VBB25468.1 - 0.095 12.8 0.7 2 8.6 0.1 2.5 2 0 0 2 2 2 0 Integrase zinc binding domain FMO-like PF00743.19 VBB25470.1 - 1e-156 522.5 0.0 1.3e-156 522.2 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 VBB25470.1 - 5.4e-26 91.5 0.0 4.2e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 VBB25470.1 - 1.9e-14 53.6 0.0 1.1e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 VBB25470.1 - 8.7e-08 31.7 0.0 1.4e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Cyclin_N PF00134.23 VBB25470.1 - 0.0001 22.0 0.2 0.00037 20.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain NAD_binding_8 PF13450.6 VBB25470.1 - 0.00022 21.4 0.5 0.0021 18.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Cyclin PF08613.11 VBB25470.1 - 0.00033 21.1 0.0 0.00096 19.5 0.0 1.8 1 0 0 1 1 1 1 Cyclin HI0933_like PF03486.14 VBB25470.1 - 0.0047 15.7 0.1 0.3 9.7 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 VBB25470.1 - 0.0059 17.1 0.3 0.077 13.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 VBB25470.1 - 0.013 15.5 0.2 0.62 10.0 0.1 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 VBB25470.1 - 0.053 12.8 0.1 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 VBB25470.1 - 0.055 12.8 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 VBB25470.1 - 0.062 12.7 0.1 0.57 9.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4897 PF16238.5 VBB25470.1 - 0.22 11.4 1.2 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) Cyclin_N PF00134.23 VBB25471.1 - 7.5e-19 67.7 0.1 2.5e-18 66.1 0.0 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 VBB25471.1 - 0.00033 20.7 0.1 0.004 17.2 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 VBB25471.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain DUF3400 PF11880.8 VBB25471.1 - 0.085 12.4 1.0 2.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) FAM195 PF14799.6 VBB25472.1 - 0.046 14.1 0.1 0.091 13.1 0.0 1.7 2 1 0 2 2 2 0 FAM195 family GAS PF13851.6 VBB25473.1 - 0.0057 16.0 21.6 0.0057 16.0 21.6 2.7 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 VBB25473.1 - 0.019 15.2 28.0 0.094 12.9 3.1 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding RseA_C PF03873.13 VBB25473.1 - 0.17 12.1 1.2 0.54 10.5 1.2 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Toxin-deaminase PF14424.6 VBB25473.1 - 7.7 6.6 9.1 6.7 6.8 1.6 2.4 1 1 1 2 2 2 0 The BURPS668_1122 family of deaminases Pneumo_att_G PF05539.11 VBB25474.1 - 0.39 10.3 5.6 0.39 10.2 5.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF747 PF05346.11 VBB25475.1 - 5.2e-86 289.0 25.6 4.1e-47 161.2 11.1 2.1 1 1 1 2 2 2 2 Eukaryotic membrane protein family Imm44 PF15571.6 VBB25475.1 - 0.099 12.9 0.1 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 44 YlaC PF10777.9 VBB25475.1 - 1.5 8.7 10.4 0.088 12.6 4.5 2.0 2 0 0 2 2 2 0 Inner membrane protein YlaC Alpha-2-MRAP_C PF06401.11 VBB25477.1 - 9.6e-33 113.9 30.9 4.2e-32 111.8 30.9 2.0 1 1 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain DUF148 PF02520.17 VBB25477.1 - 0.0041 17.2 1.3 0.0041 17.2 1.3 3.4 1 1 2 3 3 3 1 Domain of unknown function DUF148 GerD PF17898.1 VBB25477.1 - 0.23 11.4 14.0 0.039 13.9 2.2 3.5 2 2 2 4 4 4 0 Spore germination GerD central core domain DUF3323 PF11796.8 VBB25477.1 - 0.36 10.7 2.2 12 5.7 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function N-terminus (DUF3323) DASH_Hsk3 PF08227.11 VBB25477.1 - 1.3 9.5 4.1 8.6 6.8 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF3336 PF11815.8 VBB25478.1 - 0.25 11.1 2.9 0.41 10.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) LSM PF01423.22 VBB25480.1 - 7.4e-21 73.6 1.0 8.4e-21 73.4 1.0 1.1 1 0 0 1 1 1 1 LSM domain EB1 PF03271.17 VBB25481.1 - 8e-14 51.6 0.8 2e-13 50.4 0.8 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 VBB25481.1 - 2.3e-08 34.2 0.9 3.9e-08 33.4 0.9 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB25481.1 - 0.018 14.9 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain DUF2171 PF09939.9 VBB25481.1 - 0.16 12.3 0.2 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) Pkinase PF00069.25 VBB25482.1 - 1.1e-60 205.3 0.0 1.4e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25482.1 - 1.8e-37 129.1 0.0 2.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB25482.1 - 4e-08 32.9 0.0 5.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB25482.1 - 0.031 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB25482.1 - 0.073 13.0 0.2 0.45 10.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 VBB25482.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zf-C2H2_4 PF13894.6 VBB25483.1 - 1.3e-10 41.2 22.8 0.00062 20.4 0.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB25483.1 - 1.7e-07 31.4 18.1 0.0021 18.4 0.3 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB25483.1 - 3.1e-07 30.5 23.7 0.022 15.2 0.7 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 VBB25483.1 - 1e-06 28.9 4.8 0.018 15.3 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 VBB25483.1 - 6.5e-06 26.4 10.4 0.00021 21.5 3.0 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 VBB25483.1 - 0.001 19.4 0.5 0.001 19.4 0.5 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 VBB25483.1 - 0.0064 16.2 0.3 0.0064 16.2 0.3 4.6 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 VBB25483.1 - 0.012 15.8 1.3 0.022 14.9 0.0 2.0 2 1 0 3 3 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 VBB25483.1 - 0.025 14.3 8.3 0.048 13.4 0.9 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type ARS2 PF04959.13 VBB25483.1 - 0.034 14.5 0.3 7 7.0 0.0 2.4 2 1 0 2 2 2 0 Arsenite-resistance protein 2 HypA PF01155.19 VBB25483.1 - 0.081 12.9 2.1 0.44 10.6 2.1 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 VBB25483.1 - 0.1 12.2 6.5 0.79 9.4 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 VBB25483.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.4 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 VBB25483.1 - 0.25 11.7 12.5 2.3 8.6 0.4 3.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 VBB25483.1 - 0.27 11.3 7.4 7.7 6.6 7.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-TRAF PF02176.18 VBB25483.1 - 0.48 11.2 13.0 2.3 9.0 2.7 3.3 2 1 1 3 3 3 0 TRAF-type zinc finger DUF629 PF04780.12 VBB25483.1 - 0.59 8.6 8.1 2.6 6.5 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF629) CpXC PF14353.6 VBB25483.1 - 0.63 10.1 6.8 4.4 7.4 0.1 3.2 1 1 2 3 3 3 0 CpXC protein zf-Sec23_Sec24 PF04810.15 VBB25483.1 - 0.7 10.0 0.1 0.7 10.0 0.1 3.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.6 VBB25483.1 - 1.9 8.5 0.0 1.9 8.5 0.0 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 VBB25483.1 - 3 8.4 8.7 7.4 7.1 0.7 3.3 4 0 0 4 4 2 0 Autophagy receptor zinc finger-C2H2 domain DUF4379 PF14311.6 VBB25483.1 - 5 7.6 9.8 2.1 8.8 3.1 2.7 1 1 1 2 2 2 0 Probable Zinc-ribbon domain OrsD PF12013.8 VBB25483.1 - 5 7.6 15.2 7 7.1 1.5 3.8 2 1 2 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Mss51 PF13824.6 VBB25483.1 - 7.3 6.8 13.6 22 5.2 3.5 3.8 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ABC_membrane PF00664.23 VBB25484.1 - 1.2e-40 140.0 10.3 1.7e-40 139.5 10.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 VBB25484.1 - 1.3e-33 116.4 0.0 2.5e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 VBB25484.1 - 1.1e-07 31.5 2.1 2e-05 24.2 2.1 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 VBB25484.1 - 0.00039 20.8 0.0 0.0013 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 VBB25484.1 - 0.00049 19.8 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 VBB25484.1 - 0.00063 20.0 0.1 0.0028 17.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 VBB25484.1 - 0.002 17.9 0.1 0.0032 17.2 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 VBB25484.1 - 0.0034 16.2 1.2 0.014 14.2 0.3 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 VBB25484.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 VBB25484.1 - 0.011 15.3 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 VBB25484.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 VBB25484.1 - 0.017 15.3 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 VBB25484.1 - 0.019 14.8 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 VBB25484.1 - 0.023 15.2 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 VBB25484.1 - 0.04 14.4 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 VBB25484.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain RNA_helicase PF00910.22 VBB25484.1 - 0.1 13.0 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 VBB25484.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TRAP_beta PF05753.14 VBB25484.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) AAA PF00004.29 VBB25484.1 - 0.13 12.6 0.2 1.6 9.1 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 VBB25484.1 - 0.18 11.5 0.1 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 VBB25484.1 - 0.21 11.3 0.4 0.94 9.2 0.4 2.1 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 VBB25485.1 - 3.5e-70 236.4 0.0 9.4e-70 235.0 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25485.1 - 6e-33 114.2 0.0 8.8e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB25485.1 - 2e-06 27.3 0.3 7.8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB25485.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 VBB25485.1 - 0.0044 16.6 0.1 0.008 15.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 VBB25485.1 - 0.029 13.3 0.1 0.1 11.5 0.1 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 VBB25485.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 VBB25485.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase C1_1 PF00130.22 VBB25486.1 - 5.4e-07 29.4 0.4 9.1e-07 28.7 0.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 VBB25486.1 - 6.5e-07 29.8 0.2 1.4e-06 28.8 0.2 1.6 1 0 0 1 1 1 1 PH domain EGF_2 PF07974.13 VBB25487.1 - 3.2e-14 53.0 170.9 0.0015 18.8 15.9 9.5 10 0 0 10 10 10 8 EGF-like domain NHL PF01436.21 VBB25487.1 - 2e-09 37.0 5.3 0.012 15.7 0.0 6.6 8 0 0 8 8 8 3 NHL repeat RHS_repeat PF05593.14 VBB25487.1 - 5.3e-05 23.6 16.2 0.65 10.6 0.3 8.8 7 3 0 7 7 7 2 RHS Repeat SBBP PF06739.11 VBB25487.1 - 0.00044 20.2 0.1 0.14 12.1 0.0 3.8 3 0 0 3 3 3 1 Beta-propeller repeat EGF_Tenascin PF18720.1 VBB25487.1 - 0.0059 16.6 9.8 0.0059 16.6 9.8 9.0 9 0 0 9 9 9 3 Tenascin EGF domain An_peroxidase PF03098.15 VBB25489.1 - 4.6e-134 447.9 0.0 6.2e-134 447.5 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 VBB25489.1 - 3.9e-21 75.8 0.9 2.2e-20 73.3 0.9 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 VBB25489.1 - 5.7e-16 58.6 0.0 2.7e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 VBB25489.1 - 3e-14 53.2 9.0 3e-14 53.2 9.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_8 PF13833.6 VBB25489.1 - 0.023 14.6 0.7 0.082 12.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 VBB25489.1 - 0.03 14.8 3.3 0.23 12.0 0.6 3.6 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 VBB25489.1 - 0.086 12.8 0.0 0.72 9.9 0.0 2.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 VBB25489.1 - 0.13 11.9 0.1 0.51 10.0 0.1 2.2 1 0 0 1 1 1 0 EF hand HSP20 PF00011.21 VBB25490.1 - 5.2e-15 55.4 0.2 6.3e-15 55.2 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB25490.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Cypo_polyhedrin PF05865.11 VBB25490.1 - 0.12 11.7 0.0 0.45 9.9 0.0 1.7 1 1 0 1 1 1 0 Cypovirus polyhedrin protein Thioredoxin PF00085.20 VBB25491.1 - 4.1e-94 309.4 6.7 6.5e-31 106.4 0.0 4.7 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.6 VBB25491.1 - 2.6e-28 99.2 14.5 1.5e-17 64.1 0.9 4.6 4 1 1 5 5 5 4 Thioredoxin-like domain Thioredoxin_8 PF13905.6 VBB25491.1 - 1.4e-15 57.4 6.5 9.2e-05 22.7 0.0 6.7 5 3 2 7 7 7 3 Thioredoxin-like Thioredoxin_2 PF13098.6 VBB25491.1 - 4.5e-14 52.8 7.0 0.00098 19.6 0.1 5.6 3 3 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 VBB25491.1 - 1.2e-11 44.6 0.0 0.0027 17.9 0.0 3.7 3 0 0 3 3 3 3 Thioredoxin-like OST3_OST6 PF04756.13 VBB25491.1 - 1.9e-11 43.9 0.3 0.0061 16.0 0.0 3.6 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 VBB25491.1 - 2.2e-10 40.1 5.4 1.8e-08 33.9 3.4 2.9 2 1 1 3 3 3 1 Calsequestrin AhpC-TSA PF00578.21 VBB25491.1 - 3.4e-10 39.9 4.4 0.0018 18.2 0.0 4.4 3 1 1 4 4 4 3 AhpC/TSA family Thioredoxin_3 PF13192.6 VBB25491.1 - 2.3e-06 27.6 0.0 0.35 11.0 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.6 VBB25491.1 - 9.6e-06 25.6 0.0 1.2 9.0 0.0 3.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 VBB25491.1 - 1.6e-05 25.1 1.0 0.75 9.9 0.0 5.0 4 1 1 5 5 5 1 Thioredoxin Thioredoxin_5 PF13743.6 VBB25491.1 - 8e-05 22.4 2.6 4.7 6.8 0.0 5.2 3 3 3 6 6 6 1 Thioredoxin Redoxin PF08534.10 VBB25491.1 - 0.00014 21.6 4.5 2.1 8.0 0.0 4.4 4 0 0 4 4 4 1 Redoxin Thioredoxin_9 PF14595.6 VBB25491.1 - 0.00061 19.6 0.0 0.97 9.2 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin HyaE PF07449.11 VBB25491.1 - 0.0061 16.5 0.0 8.1 6.5 0.0 3.2 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 VBB25491.1 - 0.018 14.8 0.6 59 3.4 0.0 4.4 3 2 1 4 4 4 0 DSBA-like thioredoxin domain UCH_1 PF13423.6 VBB25491.1 - 0.037 13.6 0.3 5.3 6.5 0.0 2.9 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Glutaredoxin PF00462.24 VBB25491.1 - 0.12 12.7 6.9 8.9 6.6 0.0 4.4 4 1 0 4 4 4 0 Glutaredoxin Flavodoxin_3 PF12641.7 VBB25491.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain IBR PF01485.21 VBB25492.1 - 4.6e-05 23.6 4.7 4.6e-05 23.6 4.7 3.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain PUF PF00806.19 VBB25493.1 - 5.1e-36 120.3 3.1 0.00016 21.2 0.0 7.8 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Trypsin PF00089.26 VBB25493.1 - 4.7e-15 56.0 0.0 9.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 VBB25493.1 - 0.0013 19.6 0.0 0.0037 18.2 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Fez1 PF06818.15 VBB25494.1 - 0.0018 18.8 17.4 0.0018 18.8 17.4 4.0 1 1 2 3 3 3 1 Fez1 ecTbetaR2 PF08917.10 VBB25494.1 - 0.48 10.4 3.5 0.37 10.7 1.2 1.9 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain DPM3 PF08285.11 VBB25494.1 - 3 8.1 4.1 25 5.1 0.3 2.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PDZ_2 PF13180.6 VBB25495.1 - 5.4e-05 23.4 0.0 0.13 12.6 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB25495.1 - 0.019 14.8 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 PDZ domain Tricorn_PDZ PF14685.6 VBB25495.1 - 0.18 11.8 0.0 1.4 9.0 0.0 2.4 3 0 0 3 3 3 0 Tricorn protease PDZ domain Cmc1 PF08583.10 VBB25496.1 - 0.00017 21.6 2.9 0.00069 19.6 0.6 2.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 VBB25496.1 - 0.025 14.7 1.4 0.28 11.4 0.1 2.6 2 1 0 2 2 2 0 CHCH domain CX9C PF16860.5 VBB25496.1 - 0.043 13.8 1.2 0.043 13.8 1.2 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Curto_V2 PF07325.11 VBB25496.1 - 0.06 13.2 0.8 1.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Curtovirus V2 protein CUT PF02376.15 VBB25497.1 - 4.1e-71 235.1 0.1 4.5e-24 84.4 0.0 3.9 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 VBB25497.1 - 8.2e-15 54.4 3.8 8.2e-15 54.4 3.8 2.8 2 0 0 2 2 2 1 Homeodomain HNF-1_N PF04814.13 VBB25497.1 - 2e-07 31.8 26.6 6.6e-05 23.6 0.1 5.7 4 1 1 5 5 5 3 Hepatocyte nuclear factor 1 (HNF-1), N terminus YgbB PF02542.16 VBB25497.1 - 0.0047 17.2 1.4 0.014 15.7 1.4 1.8 1 0 0 1 1 1 1 YgbB family Homeobox_KN PF05920.11 VBB25497.1 - 0.0047 16.8 0.3 0.016 15.1 0.3 2.0 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 VBB25497.1 - 0.0094 15.7 0.1 0.046 13.5 0.1 2.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_34 PF13601.6 VBB25497.1 - 0.01 16.0 0.1 1.2 9.4 0.0 3.7 4 0 0 4 4 4 0 Winged helix DNA-binding domain zf-CXXC PF02008.20 VBB25498.1 - 2.9e-16 59.2 41.9 7.7e-12 45.0 21.0 2.3 2 0 0 2 2 2 2 CXXC zinc finger domain Anoctamin PF04547.12 VBB25501.1 - 3.7e-103 345.8 2.2 2.6e-65 221.0 0.2 2.2 1 1 1 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 VBB25501.1 - 2.2e-58 197.7 1.9 2.2e-58 197.7 1.9 2.3 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 VBB25501.1 - 0.034 12.9 3.5 0.026 13.3 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Cass2 PF14526.6 VBB25501.1 - 0.31 11.2 2.2 1.4 9.1 0.3 2.9 2 0 0 2 2 2 0 Integron-associated effector binding protein COBRA PF04833.15 VBB25501.1 - 0.91 9.4 5.4 0.39 10.6 1.4 2.5 2 0 0 2 2 2 0 COBRA-like protein zf-C2H2 PF00096.26 VBB25502.1 - 2.1e-18 65.6 24.9 8.9e-06 25.9 1.4 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB25502.1 - 4.8e-16 58.4 26.0 1.3e-08 34.8 0.8 5.8 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB25502.1 - 4.3e-13 48.9 22.0 0.0011 19.6 0.9 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 VBB25502.1 - 4.7e-08 32.8 21.7 0.025 14.6 0.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 VBB25502.1 - 1.5e-07 31.0 27.3 4.3e-06 26.4 2.2 5.3 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 VBB25502.1 - 1.1e-05 25.6 14.8 0.048 14.0 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 VBB25502.1 - 2.1e-05 24.2 18.4 0.041 13.6 0.3 4.5 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-BED PF02892.15 VBB25502.1 - 0.00072 19.5 16.6 0.053 13.5 0.2 4.1 3 1 1 4 4 3 2 BED zinc finger zf-MYST PF17772.1 VBB25502.1 - 0.0063 16.1 6.6 4.3 7.0 0.1 4.0 3 1 1 4 4 4 2 MYST family zinc finger domain GAGA PF09237.11 VBB25502.1 - 0.089 12.6 12.8 2 8.3 0.2 4.7 2 1 2 4 4 4 0 GAGA factor A2L_zn_ribbon PF08792.10 VBB25502.1 - 0.1 12.3 1.8 57 3.6 0.1 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain PyrI_C PF02748.15 VBB25502.1 - 0.14 12.1 9.0 0.58 10.1 0.4 3.8 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_1 PF00130.22 VBB25502.1 - 0.17 11.8 9.3 0.91 9.5 0.1 3.4 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.7 VBB25502.1 - 0.32 11.5 18.9 2.2 8.8 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 VBB25502.1 - 0.75 8.9 2.7 2.4 7.3 2.5 2.0 1 1 0 1 1 1 0 Putative actin-like family Coilin_N PF15862.5 VBB25502.1 - 1.4 8.8 13.4 87 2.9 0.0 2.9 3 1 0 3 3 3 0 Coilin N-terminus Thymidylate_kin PF02223.17 VBB25503.1 - 4.2e-38 130.9 0.0 1e-37 129.6 0.0 1.7 1 0 0 1 1 1 1 Thymidylate kinase WRW PF10206.9 VBB25503.1 - 2.4e-21 76.0 1.7 5.8e-21 74.8 1.7 1.6 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Anillin PF08174.11 VBB25503.1 - 6.8e-15 55.7 1.7 1.2e-14 54.9 0.1 2.3 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 VBB25503.1 - 2.4e-10 40.9 1.1 1.7e-08 34.9 0.0 3.9 4 0 0 4 4 4 1 PH domain KCNQ2_u3 PF16642.5 VBB25503.1 - 0.15 13.1 1.6 0.53 11.3 0.3 2.7 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Peptidase_M10 PF00413.24 VBB25504.1 - 4.2e-37 127.4 0.1 5e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 VBB25504.1 - 0.00027 20.3 0.1 0.00043 19.6 0.1 1.2 1 0 0 1 1 1 1 Met-zincin Reprolysin_3 PF13582.6 VBB25504.1 - 0.0035 17.9 0.1 0.0053 17.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 VBB25504.1 - 0.0038 17.2 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M57 PF12388.8 VBB25504.1 - 0.0074 15.9 0.1 0.0098 15.5 0.1 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Metallopep PF12044.8 VBB25504.1 - 0.0091 14.7 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 VBB25504.1 - 0.041 14.0 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 VBB25504.1 - 0.049 12.6 0.2 0.11 11.5 0.1 1.5 2 0 0 2 2 2 0 Peptidase M66 Astacin PF01400.24 VBB25504.1 - 0.086 12.5 0.3 0.24 11.0 0.2 1.8 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 VBB25504.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mss4 PF04421.13 VBB25505.1 - 1.1e-18 67.1 0.0 2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Mss4 protein DUF2552 PF10827.8 VBB25505.1 - 0.0019 18.3 0.0 0.0053 16.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2552) Snf7 PF03357.21 VBB25506.1 - 3.7e-33 114.6 18.8 5e-33 114.1 18.8 1.1 1 0 0 1 1 1 1 Snf7 YqaH PF17448.2 VBB25506.1 - 0.015 15.6 1.6 0.74 10.2 0.3 2.5 1 1 1 2 2 2 0 Uncharacterized YqaH-like LPD14 PF18827.1 VBB25506.1 - 0.064 13.5 2.1 0.12 12.6 2.0 1.6 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 14 ArsD PF06953.11 VBB25506.1 - 0.17 12.2 2.5 0.14 12.5 0.4 1.8 2 0 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD PSD4 PF07631.11 VBB25506.1 - 0.97 10.0 3.4 0.41 11.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) zf-CCCH_6 PF18585.1 VBB25506.1 - 1.1 9.2 2.9 4.7 7.2 0.4 2.8 1 1 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF3490 PF11995.8 VBB25506.1 - 1.2 8.9 8.5 0.74 9.6 6.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) CENP-Q PF13094.6 VBB25506.1 - 2.3 8.4 11.2 0.13 12.4 6.1 1.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cauli_VI PF01693.16 VBB25507.1 - 1.1e-45 153.7 17.3 8.7e-17 61.2 1.1 3.4 3 0 0 3 3 3 3 Caulimovirus viroplasmin DUF4170 PF13773.6 VBB25507.1 - 0.12 12.6 0.6 7.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) RNase_H PF00075.24 VBB25508.1 - 1.4e-27 96.6 0.2 2.4e-27 95.9 0.0 1.4 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 VBB25508.1 - 2.1e-09 37.2 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like RrnaAD PF00398.20 VBB25509.1 - 3.3e-59 200.1 0.1 4e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 VBB25509.1 - 6e-08 33.3 0.0 1.6e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB25509.1 - 1.3e-05 25.7 0.0 4e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB25509.1 - 6.9e-05 22.7 0.0 0.00014 21.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 VBB25509.1 - 0.00018 21.4 0.1 0.00033 20.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB25509.1 - 0.0002 22.1 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 VBB25509.1 - 0.00095 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 VBB25509.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 VBB25509.1 - 0.0035 16.9 0.1 0.0072 15.9 0.1 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 DREV PF05219.12 VBB25509.1 - 0.0036 16.5 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 VBB25509.1 - 0.0037 17.3 0.1 0.0076 16.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB25509.1 - 0.004 16.5 0.4 0.0087 15.4 0.1 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 VBB25509.1 - 0.0081 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 VBB25509.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 VBB25509.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 VBB25509.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 VBB25509.1 - 0.049 13.2 0.1 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 VBB25509.1 - 0.056 12.7 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 VBB25509.1 - 0.083 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) CMAS PF02353.20 VBB25509.1 - 0.095 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Sarcoglycan_1 PF04790.13 VBB25510.1 - 4.1e-63 213.2 0.0 4.6e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 VBB25510.1 - 1.7e-06 28.0 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DNA_photolyase PF00875.18 VBB25511.1 - 2.7e-10 40.5 0.0 5.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Polyoma_coat2 PF00761.20 VBB25512.1 - 0.14 11.9 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein CCT PF06203.14 VBB25512.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.3 3 0 0 3 3 3 0 CCT motif Tcp11 PF05794.13 VBB25513.1 - 3.3e-74 250.6 10.2 3.3e-74 250.6 10.2 1.9 1 1 1 2 2 2 2 T-complex protein 11 GAS PF13851.6 VBB25513.1 - 0.032 13.6 0.6 0.032 13.6 0.6 2.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding 7tm_1 PF00001.21 VBB25515.1 - 0.00068 19.0 20.2 0.00087 18.7 20.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ashwin PF15323.6 VBB25516.1 - 0.00024 21.2 1.1 0.00037 20.6 1.1 1.6 1 1 0 1 1 1 1 Developmental protein RNB PF00773.19 VBB25517.1 - 6.7e-93 311.6 0.1 1.2e-92 310.8 0.1 1.4 1 0 0 1 1 1 1 RNB domain DUF667 PF05018.13 VBB25517.1 - 4.4e-76 254.7 0.5 7.9e-76 253.9 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) OB_Dis3 PF17849.1 VBB25517.1 - 6.1e-18 64.6 0.0 1.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 VBB25517.1 - 3.9e-15 55.8 0.0 7.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 VBB25517.1 - 1.4e-06 28.4 0.0 4e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 VBB25517.1 - 2.5e-06 27.4 2.9 1.8e-05 24.6 2.9 2.3 1 1 0 1 1 1 1 S1 domain OB_RNB PF08206.11 VBB25517.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain BP28CT PF08146.12 VBB25518.1 - 9.6e-10 38.5 2.1 5e-09 36.2 0.1 3.3 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 VBB25518.1 - 2.6e-09 37.4 4.0 2.6e-09 37.4 4.0 3.1 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 Ig_6 PF18452.1 VBB25518.1 - 0.0098 15.4 0.7 0.095 12.3 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain HEAT_EZ PF13513.6 VBB25518.1 - 0.047 14.2 1.9 2.4 8.7 0.1 2.9 2 0 0 2 2 2 0 HEAT-like repeat ParcG PF10274.9 VBB25518.1 - 0.26 11.4 5.8 0.4 10.8 1.3 3.4 3 1 0 3 3 3 0 Parkin co-regulated protein RTP1_C1 PF10363.9 VBB25518.1 - 6.8 6.9 7.4 36 4.6 0.0 4.8 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ECH_1 PF00378.20 VBB25519.1 - 5.6e-29 101.2 0.0 8.9e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 VBB25519.1 - 2e-19 69.6 0.3 5.3e-19 68.2 0.3 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein Rad21_Rec8_N PF04825.13 VBB25519.1 - 3e-15 56.4 0.0 7.9e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein ECH_2 PF16113.5 VBB25519.1 - 2.4e-12 47.0 0.1 1.2e-11 44.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Rad21_Rec8 PF04824.16 VBB25519.1 - 1.7e-07 30.4 1.7 2.9e-07 29.7 0.3 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 VBB25519.1 - 0.002 18.1 0.8 0.0048 16.9 0.6 1.7 2 0 0 2 2 2 1 Segregation and condensation protein ScpA Tudor_2 PF18104.1 VBB25520.1 - 0.02 14.6 0.3 0.069 12.9 0.1 2.0 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 VBB25520.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 VBB25520.1 - 0.081 13.4 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Agenet domain Fer2_3 PF13085.6 VBB25521.1 - 2.8e-28 98.1 0.1 5.7e-27 93.9 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 VBB25521.1 - 3.7e-08 33.8 4.5 3.7e-08 33.8 4.5 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 VBB25521.1 - 8e-08 32.3 2.5 8e-08 32.3 2.5 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 VBB25521.1 - 3e-06 27.6 6.8 3e-06 27.6 6.8 3.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 VBB25521.1 - 0.015 15.2 1.3 0.015 15.2 1.3 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 VBB25521.1 - 0.016 15.8 9.7 0.024 15.2 5.0 3.1 2 2 0 2 2 2 0 4Fe-4S dicluster domain zf-UBR PF02207.20 VBB25522.1 - 0.29 11.3 9.6 0.82 9.9 1.1 3.6 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) DNA_ligase_A_M PF01068.21 VBB25524.1 - 4.6e-62 209.3 0.1 7.1e-62 208.7 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 VBB25524.1 - 9.9e-42 143.2 0.0 3.3e-41 141.5 0.0 1.9 2 1 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 VBB25524.1 - 7.1e-24 84.3 0.0 2.7e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 VBB25524.1 - 2.3e-09 37.8 0.2 3.7e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 RNA ligase DUF2330 PF10092.9 VBB25525.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) NigD_N PF12667.7 VBB25525.1 - 0.057 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 NigD-like N-terminal OB domain Presenilin PF01080.17 VBB25526.1 - 6.3 5.5 5.9 7.5 5.2 5.9 1.0 1 0 0 1 1 1 0 Presenilin Ldl_recept_a PF00057.18 VBB25527.1 - 1.1e-61 204.8 158.8 6.1e-12 45.6 9.0 9.8 11 0 0 11 11 11 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 VBB25527.1 - 6.1e-39 132.2 9.6 9.1e-12 45.3 0.1 7.1 7 0 0 7 7 7 5 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 VBB25527.1 - 1.7e-07 31.1 23.3 1.1e-05 25.2 1.5 5.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 VBB25527.1 - 2.4e-06 27.6 4.9 2.4e-06 27.6 4.9 10.4 6 4 2 9 9 9 1 Calcium-binding EGF domain SGL PF08450.12 VBB25527.1 - 8e-06 25.6 0.2 0.11 12.0 0.0 3.5 2 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 VBB25527.1 - 0.00015 22.0 3.9 0.00015 22.0 3.9 6.9 6 1 0 6 6 6 2 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 VBB25527.1 - 0.00062 20.0 0.5 0.00062 20.0 0.5 8.8 9 1 0 9 9 9 2 Pvs28 EGF domain SlpA PF03217.14 VBB25528.1 - 4.7 7.9 7.2 2.4 8.8 0.7 2.6 2 0 0 2 2 2 0 Surface later protein A domain Peptidase_C1 PF00112.23 VBB25530.1 - 2.8e-71 240.1 0.9 2.8e-71 240.1 0.9 2.0 3 0 0 3 3 3 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 VBB25530.1 - 2.7e-08 34.1 3.7 5.7e-08 33.1 3.7 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 VBB25530.1 - 0.0012 17.7 1.0 0.85 8.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Gemin6 PF06372.12 VBB25531.1 - 1.3e-09 37.9 0.1 3.2e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 VBB25531.1 - 0.012 15.7 0.0 0.05 13.7 0.0 2.1 1 0 0 1 1 1 0 Anticodon-binding domain DUF4224 PF13986.6 VBB25531.1 - 0.037 13.9 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) TAFH PF07531.14 VBB25531.1 - 0.062 13.4 0.1 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 NHR1 homology to TAF PNISR PF15996.5 VBB25532.1 - 2.7e-25 89.9 22.0 2.7e-25 89.9 22.0 4.1 1 1 2 3 3 3 1 Arginine/serine-rich protein PNISR Thioredoxin_6 PF13848.6 VBB25533.1 - 1.7e-13 50.9 2.3 1.8e-12 47.5 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 VBB25533.1 - 2.2e-12 46.9 0.0 8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.11 VBB25533.1 - 6.9e-05 22.8 0.1 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 VBB25533.1 - 7e-05 22.8 3.8 0.001 18.9 2.3 2.8 2 1 0 2 2 2 1 F plasmid transfer operon protein ERp29_N PF07912.13 VBB25533.1 - 0.0072 16.5 0.0 0.086 13.0 0.0 2.2 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_5 PF13743.6 VBB25533.1 - 0.012 15.3 0.3 0.052 13.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin DUF2681 PF10883.8 VBB25533.1 - 0.022 15.1 5.0 0.17 12.3 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Thioredoxin_2 PF13098.6 VBB25533.1 - 0.023 15.1 0.3 0.18 12.3 0.1 2.7 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 VBB25533.1 - 0.024 14.7 0.0 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain DUF4834 PF16118.5 VBB25533.1 - 0.038 14.9 4.2 0.04 14.9 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FGF-BP1 PF06473.12 VBB25533.1 - 0.11 12.4 6.1 0.12 12.2 4.8 1.5 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) DIM1 PF02966.16 VBB25533.1 - 0.13 12.1 4.1 3.3 7.5 0.1 2.5 3 0 0 3 3 3 0 Mitosis protein DIM1 Slu7 PF11708.8 VBB25533.1 - 0.16 11.7 9.7 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor TMEM51 PF15345.6 VBB25533.1 - 0.25 11.1 2.9 0.43 10.4 1.6 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 Presenilin PF01080.17 VBB25533.1 - 2.6 6.7 4.6 4.1 6.1 4.6 1.2 1 0 0 1 1 1 0 Presenilin ANAPC4_WD40 PF12894.7 VBB25534.1 - 1.2e-05 25.5 5.1 0.41 11.0 0.0 6.1 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB25534.1 - 0.62 11.0 3.9 7 7.7 0.1 4.3 3 0 0 3 3 3 0 WD domain, G-beta repeat TFIIIC_delta PF12657.7 VBB25534.1 - 0.79 9.6 3.5 0.98 9.3 0.2 2.8 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Ribosomal_S19e PF01090.19 VBB25535.1 - 1.5e-56 189.9 0.1 1.7e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GntR PF00392.21 VBB25535.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family GRIM-19 PF06212.12 VBB25536.1 - 2.2e-48 163.6 0.2 2.5e-48 163.4 0.2 1.0 1 0 0 1 1 1 1 GRIM-19 protein TPR_1 PF00515.28 VBB25537.1 - 5.9e-15 54.4 6.0 1.3e-08 34.3 0.2 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB25537.1 - 2.6e-14 52.1 4.1 7.4e-06 25.7 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB25537.1 - 6.6e-10 39.2 2.4 0.00081 19.6 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB25537.1 - 1.9e-05 24.3 3.7 0.26 11.0 0.0 3.8 2 1 2 4 4 4 2 TPR repeat TPR_6 PF13174.6 VBB25537.1 - 0.00017 22.0 1.9 0.05 14.3 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB25537.1 - 0.00019 21.4 8.2 0.068 13.4 0.3 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25537.1 - 0.0008 20.0 0.0 0.35 11.5 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB25537.1 - 0.00093 19.1 2.4 0.21 11.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB25537.1 - 0.0012 18.9 0.7 0.011 15.8 0.7 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 VBB25537.1 - 0.0024 17.3 0.3 0.35 10.4 0.3 3.4 3 0 0 3 3 3 1 SHNi-TPR ZapB PF06005.12 VBB25537.1 - 0.017 15.6 2.2 0.017 15.6 2.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB TPR_10 PF13374.6 VBB25537.1 - 0.018 14.9 1.0 0.52 10.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PA28_beta PF02252.18 VBB25537.1 - 0.022 14.4 4.6 0.44 10.2 0.1 3.3 1 1 0 3 3 3 0 Proteasome activator pa28 beta subunit TPR_14 PF13428.6 VBB25537.1 - 0.047 14.5 0.2 3.5 8.7 0.1 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.6 VBB25537.1 - 0.14 11.5 1.7 3 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF421 PF04239.12 VBB25537.1 - 0.19 11.5 3.0 0.35 10.7 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF421) UPF0242 PF06785.11 VBB25537.1 - 0.4 10.7 10.7 2.4 8.2 2.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 VBB25537.1 - 2.3 8.6 8.3 13 6.2 0.1 2.7 2 1 1 3 3 3 0 Syntaxin-like protein TMPIT PF07851.13 VBB25537.1 - 6.3 6.0 5.5 3.9 6.6 0.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF4375 PF14300.6 VBB25537.1 - 6.4 7.1 7.8 2 8.7 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF4337 PF14235.6 VBB25537.1 - 7.6 6.6 7.8 4.2 7.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) RF-1 PF00472.20 VBB25538.1 - 0.033 14.1 0.1 0.038 13.9 0.1 1.1 1 0 0 1 1 1 0 RF-1 domain Lon_C PF05362.13 VBB25539.1 - 2.7e-71 239.3 0.0 1.5e-59 201.0 0.0 3.0 3 0 0 3 3 2 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 VBB25539.1 - 2.5e-26 92.9 2.2 6.3e-26 91.5 2.2 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 VBB25539.1 - 1.2e-23 83.9 0.0 7.1e-23 81.5 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 VBB25539.1 - 1.2e-08 35.1 0.0 2.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 VBB25539.1 - 2.2e-08 34.0 0.0 5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 VBB25539.1 - 1.6e-06 28.6 0.3 1.4e-05 25.6 0.0 2.6 3 1 0 3 3 1 1 AAA ATPase domain AAA_PrkA PF08298.11 VBB25539.1 - 1.9e-06 27.0 0.1 3.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 VBB25539.1 - 2e-06 28.0 0.1 7e-06 26.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 VBB25539.1 - 2.3e-05 24.7 0.3 0.00089 19.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 VBB25539.1 - 7.1e-05 22.2 0.9 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 VBB25539.1 - 0.00079 19.2 0.0 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 VBB25539.1 - 0.0018 18.3 0.2 0.023 14.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 VBB25539.1 - 0.0043 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 VBB25539.1 - 0.0058 17.0 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 VBB25539.1 - 0.0058 16.2 0.2 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Torsin PF06309.11 VBB25539.1 - 0.0064 16.6 0.1 0.08 13.1 0.0 2.6 2 0 0 2 2 2 1 Torsin AAA_18 PF13238.6 VBB25539.1 - 0.01 16.4 1.7 0.038 14.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 VBB25539.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 VBB25539.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 VBB25539.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 VBB25539.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 VBB25539.1 - 0.02 15.1 0.0 0.07 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 VBB25539.1 - 0.021 15.1 1.1 0.081 13.2 0.1 2.4 2 1 1 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 VBB25539.1 - 0.021 14.5 0.0 0.068 12.9 0.0 1.9 1 0 0 1 1 1 0 Cytidylate kinase Viral_helicase1 PF01443.18 VBB25539.1 - 0.036 13.8 0.0 0.09 12.5 0.0 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 VBB25539.1 - 0.041 13.1 0.9 0.083 12.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.12 VBB25539.1 - 0.042 13.7 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 VBB25539.1 - 0.072 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3090 PF11290.8 VBB25539.1 - 0.09 12.6 0.2 0.81 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) ABC_tran PF00005.27 VBB25539.1 - 0.12 12.9 1.6 0.66 10.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 VBB25539.1 - 0.15 11.4 0.0 0.51 9.7 0.0 1.8 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 VBB25539.1 - 0.27 11.7 0.0 0.27 11.7 0.0 3.0 3 1 0 3 3 1 0 AAA domain DFF-C PF09033.10 VBB25539.1 - 0.39 10.6 4.4 1 9.2 4.4 1.7 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain SPC12 PF06645.13 VBB25540.1 - 9.7e-28 96.1 1.4 1.2e-27 95.8 1.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) BCNT PF07572.12 VBB25541.1 - 1.5e-26 92.3 0.4 3.6e-26 91.0 0.4 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development YL1 PF05764.13 VBB25541.1 - 0.014 15.6 11.0 0.017 15.2 11.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Spt5_N PF11942.8 VBB25541.1 - 1.1 10.2 11.8 0.23 12.5 8.0 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TB2_DP1_HVA22 PF03134.19 VBB25542.1 - 3.3e-23 81.4 8.1 5.7e-23 80.6 8.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RAB3GAP2_N PF14655.6 VBB25543.1 - 1.6e-108 363.6 0.0 2.5e-108 363.0 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 VBB25543.1 - 3.1e-34 118.2 6.1 2.2e-19 69.1 0.0 3.9 2 1 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus SRP54 PF00448.22 VBB25544.1 - 4.1e-51 173.4 1.3 4.1e-51 173.4 1.3 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 VBB25544.1 - 3e-47 162.0 21.6 4.1e-47 161.5 21.6 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 VBB25544.1 - 3.2e-10 40.1 0.0 1.5e-09 37.9 0.0 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 VBB25544.1 - 7.7e-07 28.4 0.2 8.6e-06 24.9 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 VBB25544.1 - 4.9e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 VBB25544.1 - 0.00046 20.2 0.8 0.16 12.1 0.0 2.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 VBB25544.1 - 0.0035 17.8 2.1 0.02 15.3 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 VBB25544.1 - 0.0038 17.5 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 VBB25544.1 - 0.0062 16.6 2.9 0.014 15.5 0.0 3.0 3 2 0 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.6 VBB25544.1 - 0.0067 16.6 0.2 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 VBB25544.1 - 0.0088 15.3 0.0 0.034 13.4 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin ArsA_ATPase PF02374.15 VBB25544.1 - 0.0088 15.3 0.0 0.0088 15.3 0.0 2.5 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 VBB25544.1 - 0.015 15.2 0.7 0.071 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 VBB25544.1 - 0.023 14.2 0.1 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 VBB25544.1 - 0.025 14.5 0.2 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase ParA PF10609.9 VBB25544.1 - 0.034 13.6 0.0 0.094 12.1 0.0 1.8 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NTPase_1 PF03266.15 VBB25544.1 - 0.038 13.9 0.2 1.4 8.8 0.2 3.0 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.6 VBB25544.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 VBB25544.1 - 0.81 10.2 0.0 0.81 10.2 0.0 3.4 2 1 0 2 2 1 0 ABC transporter BRCT_3 PF18428.1 VBB25545.1 - 7.8e-27 93.3 0.6 7.9e-22 77.2 0.0 4.0 3 1 1 4 4 4 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 VBB25545.1 - 5.5e-14 52.3 0.3 4.3e-11 43.0 0.0 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 VBB25545.1 - 3.1e-13 49.9 0.0 2.7e-09 37.3 0.0 3.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 VBB25545.1 - 1e-08 34.9 0.3 2.8e-07 30.3 0.0 3.3 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain Tudor_3 PF18115.1 VBB25545.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain E1-E2_ATPase PF00122.20 VBB25546.1 - 4.1e-51 173.1 0.0 4.1e-51 173.1 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 VBB25546.1 - 1.2e-18 67.5 0.2 1.2e-18 67.5 0.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 VBB25546.1 - 1.3e-16 61.5 2.2 2.4e-15 57.4 2.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 VBB25546.1 - 2.9e-16 58.9 0.0 7e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 VBB25546.1 - 2.3e-14 53.3 0.0 7.6e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 VBB25546.1 - 0.00019 21.3 0.7 0.00043 20.1 0.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Kelch_1 PF01344.25 VBB25547.1 - 5.2e-82 269.2 11.3 3.7e-17 61.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 VBB25547.1 - 1.9e-43 145.4 2.6 3.2e-07 30.4 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 VBB25547.1 - 1.7e-34 116.5 3.0 4.9e-07 29.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 VBB25547.1 - 7.9e-31 106.2 0.3 2.1e-30 104.9 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 VBB25547.1 - 4.4e-28 97.0 1.3 0.00017 21.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 VBB25547.1 - 3.6e-27 94.1 0.4 8.1e-05 22.5 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 VBB25547.1 - 2.8e-25 88.7 0.3 5.9e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Kelch_5 PF13854.6 VBB25547.1 - 1e-07 31.8 11.3 0.0056 16.6 0.3 5.0 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 VBB25547.1 - 3.5e-05 23.9 0.2 0.014 15.5 0.1 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) YjcQ PF09639.10 VBB25547.1 - 0.051 13.8 0.0 5.9 7.2 0.0 2.7 2 0 0 2 2 2 0 YjcQ protein Thioredoxin PF00085.20 VBB25548.1 - 1.3e-17 63.6 1.1 2.1e-16 59.8 0.2 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 VBB25548.1 - 1.6e-17 64.0 9.0 2.2e-11 44.0 2.3 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 VBB25548.1 - 4.6e-08 33.3 6.2 6.8e-05 23.1 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 VBB25548.1 - 6.3e-07 29.2 0.4 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 VBB25548.1 - 5.5e-05 23.1 1.5 0.00034 20.5 0.1 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 VBB25548.1 - 0.014 15.8 1.9 0.023 15.1 0.3 2.3 2 2 1 3 3 3 0 Thioredoxin-like domain SEA PF01390.20 VBB25548.1 - 0.017 15.2 1.0 0.023 14.8 0.0 1.7 2 0 0 2 2 2 0 SEA domain Thioredoxin_7 PF13899.6 VBB25548.1 - 0.023 14.9 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like DUF3408 PF11888.8 VBB25548.1 - 0.22 11.7 0.2 0.22 11.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) SID-1_RNA_chan PF13965.6 VBB25548.1 - 0.23 9.9 2.1 0.33 9.3 2.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TraF PF13728.6 VBB25548.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 F plasmid transfer operon protein UQ_con PF00179.26 VBB25550.1 - 1.2e-45 154.6 0.0 1.5e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C4 PF00105.18 VBB25551.1 - 2e-07 31.4 1.3 3.8e-07 30.5 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) BfiI_DBD PF18243.1 VBB25551.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain DUF5600 PF18150.1 VBB25552.1 - 5.3e-14 52.7 0.7 5.3e-14 52.7 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 VBB25552.1 - 1.8e-08 34.4 0.0 5.3e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 VBB25552.1 - 1.7e-07 31.5 0.1 1.7e-07 31.5 0.1 2.9 2 2 0 2 2 2 1 Dynamin family EHD_N PF16880.5 VBB25552.1 - 2.7e-05 23.9 1.1 7.4e-05 22.6 1.1 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Roc PF08477.13 VBB25552.1 - 0.0086 16.3 0.1 2.2 8.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 VBB25552.1 - 0.018 14.4 3.3 1.1 8.5 0.2 2.8 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 VBB25552.1 - 0.044 13.7 0.2 6.9 6.5 0.0 2.8 2 1 1 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 VBB25552.1 - 0.045 13.3 0.7 0.14 11.7 0.2 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Shisa PF13908.6 VBB25553.1 - 0.075 13.3 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Phosphodiest PF01663.22 VBB25554.1 - 9.8e-77 258.9 0.1 1.2e-76 258.6 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DCP1 PF06058.13 VBB25554.1 - 0.014 15.3 0.0 0.95 9.4 0.0 2.8 3 0 0 3 3 3 0 Dcp1-like decapping family IF-2B PF01008.17 VBB25555.1 - 2.9e-42 144.8 2.9 3.5e-42 144.5 0.1 2.1 2 1 0 2 2 2 1 Initiation factor 2 subunit family FAM220 PF15487.6 VBB25555.1 - 0.85 9.2 5.9 1.5 8.4 5.9 1.3 1 0 0 1 1 1 0 FAM220 family PC_rep PF01851.22 VBB25556.1 - 1.6e-24 85.1 12.0 1.2e-05 25.5 0.3 6.9 6 0 0 6 6 6 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 VBB25556.1 - 0.00049 20.4 6.7 0.017 15.5 0.2 4.6 5 1 0 5 5 5 1 HEAT repeats TPR_19 PF14559.6 VBB25556.1 - 0.043 14.3 7.5 0.91 10.1 0.6 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF2274 PF10038.9 VBB25556.1 - 0.093 13.2 0.3 6.7 7.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) TPR_14 PF13428.6 VBB25556.1 - 2.8 9.0 9.4 57 4.9 0.4 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB25556.1 - 4.8 7.5 5.9 35 4.7 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 7tm_1 PF00001.21 VBB25557.1 - 4e-40 137.8 13.4 5.5e-40 137.4 13.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RPN2_C PF18004.1 VBB25558.1 - 1.1e-46 158.7 11.3 1.9e-46 157.9 11.3 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 VBB25558.1 - 1.3e-12 47.5 3.8 2.8e-07 30.6 0.1 2.6 2 0 0 2 2 2 2 Proteasome/cyclosome repeat HEAT_2 PF13646.6 VBB25558.1 - 3.8e-05 24.0 0.0 6.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 VBB25558.1 - 0.0025 18.3 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 HEAT-like repeat DUF4509 PF14970.6 VBB25558.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4509) Pombe_5TM PF09437.10 VBB25558.1 - 0.19 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Pombe specific 5TM protein HEAT PF02985.22 VBB25558.1 - 0.19 12.0 0.0 26 5.4 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat Vfa1 PF08432.10 VBB25558.1 - 0.24 11.7 10.3 0.37 11.1 10.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PRORP PF16953.5 VBB25559.1 - 4.7e-25 88.5 0.2 7.6e-25 87.8 0.2 1.3 1 0 0 1 1 1 1 Protein-only RNase P COX6B PF02297.17 VBB25559.1 - 2.3e-13 50.2 9.5 6.7e-13 48.7 9.5 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sec1 PF00995.23 VBB25560.1 - 5.5e-113 379.2 4.8 6.7e-113 378.9 4.8 1.1 1 0 0 1 1 1 1 Sec1 family V-ATPase_H_C PF11698.8 VBB25560.1 - 0.015 15.4 0.0 0.052 13.7 0.0 1.9 1 0 0 1 1 1 0 V-ATPase subunit H DivIC PF04977.15 VBB25560.1 - 0.018 14.8 2.1 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator BAT2_N PF07001.11 VBB25562.1 - 9.7e-21 75.1 12.2 9.7e-21 75.1 12.2 8.8 8 2 1 9 9 9 2 BAT2 N-terminus Dehydrin PF00257.19 VBB25564.1 - 0.14 12.8 3.0 0.15 12.6 3.0 1.1 1 0 0 1 1 1 0 Dehydrin UPF0242 PF06785.11 VBB25565.1 - 0.09 12.9 3.6 0.12 12.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Amidase PF01425.21 VBB25566.1 - 9.6e-80 268.7 0.0 1.4e-79 268.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Innexin PF00876.18 VBB25567.1 - 3.4e-61 207.5 14.2 3e-48 164.9 11.0 2.5 1 1 1 2 2 2 2 Innexin Ank_2 PF12796.7 VBB25567.1 - 2.3e-59 197.9 22.5 4.3e-13 49.7 0.1 10.6 3 3 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB25567.1 - 2.3e-56 187.5 18.1 1.5e-12 47.8 0.0 14.2 8 2 7 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB25567.1 - 1.7e-41 135.5 40.6 0.0088 16.5 0.1 20.6 21 0 0 21 21 21 10 Ankyrin repeat Ank_5 PF13857.6 VBB25567.1 - 3.2e-41 138.8 19.4 1.7e-06 28.2 0.0 12.8 8 3 5 14 14 14 9 Ankyrin repeats (many copies) Ank PF00023.30 VBB25567.1 - 9.2e-30 101.8 30.9 4.3e-05 23.8 0.1 17.3 18 0 0 18 18 18 5 Ankyrin repeat FYVE PF01363.21 VBB25567.1 - 2e-12 47.0 7.1 2e-12 47.0 7.1 2.5 3 0 0 3 3 3 1 FYVE zinc finger BTB PF00651.31 VBB25567.1 - 2e-10 40.9 0.0 8.6e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 VBB25567.1 - 0.0065 16.5 0.4 0.019 15.1 0.4 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Zn_Tnp_IS1595 PF12760.7 VBB25567.1 - 4.5 7.3 9.7 13 5.8 9.7 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain CBM_25 PF03423.13 VBB25568.1 - 0.0091 16.2 0.3 0.018 15.3 0.3 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) EAP30 PF04157.16 VBB25568.1 - 0.043 13.1 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Ribosomal_S19 PF00203.21 VBB25569.1 - 5.3e-34 115.9 0.2 7.6e-34 115.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 vATP-synt_AC39 PF01992.16 VBB25570.1 - 1.8e-59 202.0 1.2 1.9e-59 201.8 1.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF4176 PF13780.6 VBB25570.1 - 0.14 12.2 0.1 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) vATP-synt_AC39 PF01992.16 VBB25571.1 - 5e-46 157.7 0.0 6.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pkinase_Tyr PF07714.17 VBB25572.1 - 8.7e-81 271.0 0.0 1.4e-80 270.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB25572.1 - 3.2e-41 141.4 0.1 9.5e-41 139.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Focal_AT PF03623.13 VBB25572.1 - 2.7e-39 134.2 2.5 5e-39 133.3 0.2 2.5 3 0 0 3 3 3 1 Focal adhesion targeting region FERM_M PF00373.18 VBB25572.1 - 7.3e-09 36.1 0.4 1.9e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_N_2 PF18038.1 VBB25572.1 - 1.4e-05 25.8 0.7 5.7e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain Kinase-like PF14531.6 VBB25572.1 - 0.014 14.8 0.5 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_polyA_pol_N PF12630.7 VBB25572.1 - 0.31 11.4 1.7 12 6.3 0.1 3.2 3 0 0 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Tyrosinase PF00264.20 VBB25573.1 - 2.9e-34 119.3 2.3 7.8e-34 117.9 0.1 2.5 2 1 0 2 2 2 1 Common central domain of tyrosinase ShK PF01549.24 VBB25573.1 - 5.5e-26 90.8 69.4 1.1e-07 32.2 10.7 5.1 4 0 0 4 4 4 4 ShK domain-like zf-CCCH PF00642.24 VBB25573.1 - 0.0095 15.8 13.7 0.1 12.6 0.2 4.8 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tyrosinase PF00264.20 VBB25574.1 - 9.2e-29 101.3 4.6 9.2e-29 101.3 4.6 3.4 2 2 0 2 2 2 1 Common central domain of tyrosinase ShK PF01549.24 VBB25574.1 - 8.7e-13 48.6 27.6 1.6e-07 31.7 7.8 3.1 2 0 0 2 2 2 2 ShK domain-like Sema PF01403.19 VBB25575.1 - 7.7e-89 298.4 0.0 1.1e-88 298.0 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 VBB25575.1 - 0.0003 21.3 6.6 0.0011 19.5 6.6 2.0 1 0 0 1 1 1 1 Plexin repeat Ig_3 PF13927.6 VBB25575.1 - 0.00047 20.7 0.4 0.0022 18.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 VBB25575.1 - 0.006 16.9 0.0 0.032 14.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 VBB25575.1 - 0.046 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain DPPIV_N PF00930.21 VBB25576.1 - 7.2e-71 238.8 1.4 1.2e-70 238.1 1.4 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 VBB25576.1 - 5.1e-47 160.1 0.3 9.7e-47 159.2 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 VBB25576.1 - 3.9e-07 29.6 0.0 0.015 14.6 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 VBB25576.1 - 8.9e-05 22.2 1.5 0.014 15.0 0.1 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 VBB25576.1 - 0.0018 18.0 0.3 0.016 14.9 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 VBB25576.1 - 0.0063 16.1 0.0 0.02 14.4 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.8 VBB25576.1 - 0.0081 15.4 0.2 0.11 11.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 VBB25576.1 - 0.01 16.5 0.0 0.11 13.1 0.0 2.3 2 1 1 3 3 3 0 Alpha/beta hydrolase family Esterase PF00756.20 VBB25576.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 VBB25576.1 - 0.013 15.4 0.0 0.082 12.8 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 VBB25576.1 - 0.019 13.8 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_2 PF02230.16 VBB25576.1 - 0.11 12.2 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RRM_1 PF00076.22 VBB25577.1 - 8.8e-32 108.8 0.1 2e-11 43.6 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.23 VBB25577.1 - 2.9e-06 27.0 0.9 7.8e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 VBB25578.1 - 2e-10 40.6 0.4 3.3e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ASH PF15780.5 VBB25578.1 - 0.019 15.1 0.0 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RhoGAP PF00620.27 VBB25578.1 - 0.056 13.3 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 RhoGAP domain Lsm_interact PF05391.11 VBB25578.1 - 0.28 10.7 2.4 0.43 10.2 1.2 1.9 2 0 0 2 2 2 0 Lsm interaction motif BSD PF03909.17 VBB25579.1 - 8.7e-15 54.5 0.5 3e-14 52.8 0.5 2.0 1 0 0 1 1 1 1 BSD domain Laminin_G_1 PF00054.23 VBB25579.1 - 0.085 13.1 0.8 4.8 7.4 0.0 2.5 1 1 1 2 2 2 0 Laminin G domain SelB-wing_1 PF09105.10 VBB25579.1 - 0.42 10.6 2.1 0.67 10.0 0.7 2.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Reeler PF02014.16 VBB25581.1 - 2.8e-13 50.7 0.0 1.9e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 Reeler domain DUF1794 PF08768.11 VBB25581.1 - 4.8e-10 39.6 0.0 1.5e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1794) EGF PF00008.27 VBB25581.1 - 1.5e-09 38.0 14.3 1.2e-07 31.9 5.0 2.7 2 0 0 2 2 2 2 EGF-like domain ShK PF01549.24 VBB25581.1 - 9.7e-08 32.4 10.2 2.8e-07 31.0 10.2 1.9 1 0 0 1 1 1 1 ShK domain-like hEGF PF12661.7 VBB25581.1 - 0.026 15.2 4.9 0.026 15.2 4.9 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF SLBP_RNA_bind PF15247.6 VBB25584.1 - 1.9e-20 72.7 7.0 1.9e-20 72.7 7.0 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Acyl_transf_3 PF01757.22 VBB25586.1 - 1.4e-14 53.9 26.3 3.2e-14 52.7 26.3 1.5 1 0 0 1 1 1 1 Acyltransferase family Trep_Strep PF09605.10 VBB25586.1 - 0.027 14.4 0.8 0.027 14.4 0.8 3.2 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Ribosomal_L20 PF00453.18 VBB25588.1 - 3.1e-16 59.4 0.3 3.9e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 DUF2087 PF09860.9 VBB25588.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) GntR PF00392.21 VBB25588.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family WD40 PF00400.32 VBB25590.1 - 7.7e-42 140.5 16.4 5e-08 33.5 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB25590.1 - 4.3e-22 78.2 5.5 0.00036 20.8 0.3 5.9 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB25590.1 - 0.00067 19.1 0.0 1 8.6 0.0 2.2 1 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 VBB25590.1 - 0.0012 17.9 0.2 2.3 7.1 0.1 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TTR-52 PF01060.23 VBB25590.1 - 0.0083 16.8 0.1 0.051 14.3 0.0 2.2 2 0 0 2 2 2 1 Transthyretin-like family Motile_Sperm PF00635.26 VBB25591.1 - 1.1e-16 60.6 0.1 1.1e-16 60.6 0.1 2.1 3 0 0 3 3 3 1 MSP (Major sperm protein) domain ShK PF01549.24 VBB25591.1 - 0.00012 22.6 4.1 0.00012 22.6 4.1 3.5 3 0 0 3 3 3 2 ShK domain-like MobL PF18555.1 VBB25591.1 - 0.068 12.4 2.9 0.13 11.5 2.9 1.4 1 0 0 1 1 1 0 MobL relaxases ThiF PF00899.21 VBB25592.1 - 8.4e-54 182.5 0.0 2.4e-53 181.0 0.0 1.6 1 1 0 1 1 1 1 ThiF family E2_bind PF08825.10 VBB25592.1 - 1.8e-15 56.8 0.1 2.9e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 VBB25592.1 - 0.00021 21.8 0.0 0.00044 20.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 VBB25592.1 - 0.0061 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MRG PF05712.13 VBB25593.1 - 1.3e-28 99.7 0.1 2.1e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 VBB25593.1 - 0.01 15.7 1.1 0.16 11.9 0.0 2.7 2 1 0 2 2 2 0 RNA binding activity-knot of a chromodomain Pneumo_phosprot PF02478.16 VBB25593.1 - 0.054 13.0 0.5 0.087 12.4 0.5 1.3 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Tudor_2 PF18104.1 VBB25593.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain eIF-5a PF01287.20 VBB25594.1 - 5e-25 87.4 0.3 7.4e-25 86.9 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 VBB25594.1 - 0.00045 20.2 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-C2H2 PF00096.26 VBB25595.1 - 1.8e-15 56.4 53.4 0.0021 18.4 0.7 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB25595.1 - 3.8e-15 55.3 51.7 0.0047 17.7 0.4 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB25595.1 - 4.1e-08 33.3 4.5 1e-05 25.7 1.1 8.2 8 1 0 8 8 7 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 VBB25595.1 - 1.2e-06 28.4 32.2 0.097 12.7 1.0 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf_UBZ PF18439.1 VBB25595.1 - 0.00024 20.7 22.0 1.3 8.6 0.3 6.3 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 VBB25595.1 - 0.017 15.5 20.8 0.8 10.2 0.3 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB25595.1 - 0.022 15.0 29.3 0.03 14.6 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 VBB25595.1 - 0.028 14.6 36.0 0.27 11.5 3.7 6.3 2 1 4 7 7 7 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 VBB25595.1 - 0.031 14.4 27.2 0.087 13.0 4.7 5.6 4 2 1 5 5 5 0 Zinc ribbon domain XPA_N PF01286.18 VBB25595.1 - 0.15 12.1 0.1 0.15 12.1 0.1 5.9 6 0 0 6 6 6 0 XPA protein N-terminal zf-HIT PF04438.16 VBB25595.1 - 1.4 8.8 27.5 1.5 8.7 0.6 6.3 6 0 0 6 6 6 0 HIT zinc finger Zn-C2H2_12 PF18112.1 VBB25595.1 - 5.5 7.6 10.5 0.74 10.3 0.3 3.5 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain zf-WRNIP1_ubi PF18279.1 VBB25595.1 - 7.3 7.5 7.2 14 6.6 0.3 4.0 5 0 0 5 5 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_8 PF15909.5 VBB25595.1 - 8.4 6.8 33.4 4.5 7.6 4.1 4.3 1 1 3 4 4 4 0 C2H2-type zinc ribbon OrfB_IS605 PF01385.19 VBB25596.1 - 0.049 13.9 0.1 0.075 13.3 0.1 1.2 1 0 0 1 1 1 0 Probable transposase Voltage_CLC PF00654.20 VBB25598.1 - 3.3e-77 260.1 26.5 3.3e-77 260.1 26.5 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 VBB25598.1 - 0.0048 17.3 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain DNA_pol_B_thumb PF14791.6 VBB25598.1 - 0.025 14.7 0.1 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase beta thumb BTB PF00651.31 VBB25599.1 - 4.3e-06 26.9 0.1 1.2e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 VBB25599.1 - 0.0055 16.8 1.3 0.01 15.9 0.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Aminotran_5 PF00266.19 VBB25601.1 - 6e-59 199.9 0.0 7e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CI-B14_5a PF07347.12 VBB25602.1 - 5e-15 55.2 0.6 5e-15 55.2 0.6 1.9 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) MTHFR PF02219.17 VBB25605.1 - 5.6e-83 278.6 0.0 7.5e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase WD40 PF00400.32 VBB25606.1 - 2.2e-20 72.6 12.1 3.6e-05 24.4 0.7 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 VBB25606.1 - 0.0015 17.3 0.6 0.18 10.5 0.3 2.7 1 1 2 3 3 3 1 Nup133 N terminal like PQQ_3 PF13570.6 VBB25606.1 - 0.0079 16.7 0.0 1.2 9.8 0.0 3.0 3 0 0 3 3 3 1 PQQ-like domain WD40_like PF17005.5 VBB25606.1 - 0.03 13.7 0.0 7.8 5.7 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain ANAPC4_WD40 PF12894.7 VBB25606.1 - 0.051 13.9 0.1 12 6.3 0.0 3.7 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 VBB25606.1 - 0.22 10.5 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 Coatomer WD associated region CDC45 PF02724.14 VBB25606.1 - 0.23 9.7 7.2 0.31 9.3 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 VBB25606.1 - 0.33 11.4 15.9 0.68 10.4 15.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 VBB25606.1 - 0.5 10.6 8.7 1.1 9.5 8.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 VBB25606.1 - 2 8.1 15.2 3 7.5 15.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 VBB25606.1 - 3.4 6.1 10.8 5.1 5.6 10.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 VBB25606.1 - 3.7 5.6 6.5 4.9 5.2 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 VBB25606.1 - 10 5.4 14.6 15 4.8 14.6 1.2 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 VBB25607.1 - 3.2e-12 46.1 0.0 5.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAGA-Tad1 PF12767.7 VBB25607.1 - 0.038 13.7 0.3 0.056 13.2 0.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Snf7 PF03357.21 VBB25608.1 - 1.8e-22 79.7 14.5 1.8e-22 79.7 14.5 1.5 2 0 0 2 2 2 1 Snf7 RPT PF13446.6 VBB25608.1 - 0.019 14.9 1.1 0.038 13.9 1.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein RVT_connect PF06815.13 VBB25608.1 - 0.12 12.6 0.9 0.19 12.0 0.9 1.3 1 0 0 1 1 1 0 Reverse transcriptase connection domain Pterin_4a PF01329.19 VBB25609.1 - 2.8e-30 104.3 0.0 4.1e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase adh_short_C2 PF13561.6 VBB25610.1 - 3.8e-50 170.6 0.1 1e-43 149.6 0.0 2.8 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase UCH PF00443.29 VBB25610.1 - 1.1e-43 149.6 0.0 4.4e-43 147.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 VBB25610.1 - 9.5e-38 129.6 0.2 1e-27 96.9 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase UCH_1 PF13423.6 VBB25610.1 - 1.8e-05 24.5 21.4 0.00064 19.4 10.1 3.6 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase OTU PF02338.19 VBB25610.1 - 2.4e-05 24.8 0.0 6.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease KR PF08659.10 VBB25610.1 - 4e-05 23.6 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 KR domain CK_II_beta PF01214.18 VBB25611.1 - 8.5e-65 218.0 0.8 8.9e-63 211.4 0.8 2.1 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PAP_assoc PF03828.19 VBB25612.1 - 9.6e-14 51.3 0.0 2.5e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 VBB25612.1 - 0.068 13.3 0.2 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Ribosomal_L18p PF00861.22 VBB25614.1 - 0.022 15.1 0.1 0.052 13.9 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast LSDAT_euk PF18139.1 VBB25615.1 - 1e-108 362.8 0.0 1.6e-108 362.1 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 VBB25615.1 - 2.3e-20 72.7 0.2 4.1e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 VBB25615.1 - 1.5e-13 50.5 27.7 2.7e-13 49.7 27.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ras PF00071.22 VBB25616.1 - 7.3e-65 217.5 0.3 8.5e-65 217.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB25616.1 - 7.8e-36 122.9 0.5 1.3e-35 122.2 0.3 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB25616.1 - 4.3e-16 58.9 0.3 6.7e-16 58.2 0.3 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB25616.1 - 2.5e-06 27.0 0.1 3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 VBB25616.1 - 4.3e-05 23.0 0.1 5.8e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 VBB25616.1 - 0.0005 19.7 0.2 0.0012 18.5 0.1 1.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB25616.1 - 0.00051 20.1 0.0 0.00075 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB25616.1 - 0.0031 17.5 0.1 1.7 8.5 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase TniB PF05621.11 VBB25616.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 VBB25616.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 VBB25616.1 - 0.049 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Septin DUF3963 PF13124.6 VBB25616.1 - 0.16 12.0 0.2 0.42 10.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_16 PF13191.6 VBB25616.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Arm PF00514.23 VBB25617.1 - 0.0002 21.3 3.4 1 9.5 0.1 3.8 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat APC_rep PF18797.1 VBB25618.1 - 0.00019 22.3 0.2 0.00058 20.7 0.2 1.8 1 1 0 1 1 1 1 Adenomatous polyposis coli (APC) repeat HTH_Tnp_Tc5 PF03221.16 VBB25619.1 - 6.7e-27 93.3 5.0 3.5e-13 49.4 0.4 2.9 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain BrkDBD PF09607.10 VBB25619.1 - 0.00022 20.9 0.2 0.00078 19.2 0.2 1.9 1 0 0 1 1 1 1 Brinker DNA-binding domain DDE_1 PF03184.19 VBB25619.1 - 0.0091 15.7 2.6 0.13 11.9 0.5 3.4 4 0 0 4 4 4 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 VBB25619.1 - 0.014 15.7 0.0 0.055 13.8 0.0 2.0 1 0 0 1 1 1 0 Transposase PapB PF03333.13 VBB25619.1 - 0.14 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein Ribonuclease_3 PF00636.26 VBB25619.1 - 2.2 9.0 4.2 1.3 9.7 0.6 2.5 2 1 0 2 2 2 0 Ribonuclease III domain Caskin1-CID PF16600.5 VBB25619.1 - 4.1 8.0 6.8 16 6.2 6.8 2.0 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Neur_chan_LBD PF02931.23 VBB25620.1 - 1.5e-57 194.5 4.6 5.5e-57 192.7 2.8 2.3 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB25620.1 - 1.3e-42 146.5 13.6 5.4e-36 124.8 7.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Oxidored_q3 PF00499.20 VBB25620.1 - 0.14 11.9 5.1 0.025 14.3 0.8 1.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MgtE PF01769.16 VBB25620.1 - 1.1 9.6 9.6 4.5 7.7 5.7 2.7 2 1 0 2 2 2 0 Divalent cation transporter EF-hand_1 PF00036.32 VBB25621.1 - 1.5e-24 83.7 1.6 1.4e-07 30.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 VBB25621.1 - 2.6e-24 85.5 4.5 5.9e-14 52.3 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB25621.1 - 6e-21 72.5 1.8 1.2e-06 27.9 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 VBB25621.1 - 5.5e-20 71.0 6.9 9.5e-08 31.8 0.5 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB25621.1 - 1.5e-16 59.0 0.6 9.8e-05 21.7 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 VBB25621.1 - 2.6e-11 43.6 0.0 0.00018 21.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 VBB25621.1 - 1.2e-07 31.6 0.9 0.0017 18.3 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Endotoxin_C2 PF18449.1 VBB25621.1 - 0.013 15.8 0.1 0.057 13.7 0.0 1.9 2 0 0 2 2 2 0 Delta endotoxin Caleosin PF05042.13 VBB25621.1 - 0.019 14.9 0.5 0.89 9.5 0.1 2.7 2 1 1 3 3 3 0 Caleosin related protein T3RM_EcoP15I_C PF18273.1 VBB25621.1 - 0.031 14.6 0.3 0.24 11.7 0.1 2.0 1 1 1 2 2 2 0 Type III R-M EcoP15I C-terminal domain EF-hand_10 PF14788.6 VBB25621.1 - 0.035 14.0 1.2 8.9 6.3 0.1 2.4 2 0 0 2 2 2 0 EF hand Ribosomal_S20p PF01649.18 VBB25621.1 - 0.066 13.9 0.4 0.75 10.5 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S20 EF-hand_11 PF08976.11 VBB25621.1 - 0.091 13.6 0.0 0.91 10.4 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain Astacin PF01400.24 VBB25622.1 - 6.6e-67 224.8 0.1 1.9e-66 223.3 0.1 1.9 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CTD_bind PF04818.13 VBB25622.1 - 1.5e-11 44.9 0.1 1.5e-11 44.9 0.1 3.3 4 0 0 4 4 4 1 RNA polymerase II-binding domain. CUB PF00431.20 VBB25622.1 - 5.3e-07 30.0 0.4 2.5e-06 27.8 0.4 2.2 1 0 0 1 1 1 1 CUB domain CTK3 PF12243.8 VBB25622.1 - 0.011 15.7 0.3 0.047 13.7 0.1 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Reprolysin_4 PF13583.6 VBB25622.1 - 0.013 15.2 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MIF4G_like PF09088.11 VBB25623.1 - 1.2e-34 119.7 0.5 6.5e-34 117.4 0.5 2.3 1 1 1 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 VBB25623.1 - 1.7e-32 113.0 6.8 1.7e-32 113.0 6.8 2.1 3 0 0 3 3 3 1 MIF4G like MIF4G PF02854.19 VBB25623.1 - 3.7e-21 75.7 2.7 2.4e-20 73.1 0.5 2.7 2 1 0 2 2 2 1 MIF4G domain HGD-D PF06050.13 VBB25623.1 - 0.14 11.9 0.4 0.27 10.9 0.4 1.5 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component dCache_3 PF14827.6 VBB25623.1 - 0.31 10.6 1.6 4 7.0 0.1 2.3 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase Vac14_Fig4_bd PF11916.8 VBB25623.1 - 0.67 9.6 6.2 0.74 9.5 0.3 3.1 3 0 0 3 3 3 0 Vacuolar protein 14 C-terminal Fig4p binding TPR_11 PF13414.6 VBB25624.1 - 0.00025 20.6 0.0 0.62 9.8 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 VBB25624.1 - 0.001 19.7 3.6 4.7 8.3 0.0 4.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25624.1 - 0.0042 17.7 0.6 3 8.6 0.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB25624.1 - 0.011 16.0 4.7 0.66 10.3 0.2 4.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB25624.1 - 0.11 12.4 8.2 0.84 9.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 VBB25624.1 - 0.2 11.8 4.7 2.1 8.5 0.0 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 VBB25624.1 - 0.25 11.6 10.9 5.4 7.4 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 VBB25624.1 - 0.37 10.7 3.3 17 5.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB25624.1 - 1.3 9.3 5.1 5.9 7.2 0.2 3.8 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 VBB25624.1 - 4.4 7.8 4.9 7.9 7.0 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MarR PF01047.22 VBB25625.1 - 0.025 14.5 0.1 3.7 7.6 0.0 3.6 4 0 0 4 4 4 0 MarR family SPRY PF00622.28 VBB25626.1 - 5.9e-18 65.1 0.1 1.1e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 VBB25626.1 - 4.1e-10 39.4 8.9 1.1e-09 38.0 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB25626.1 - 0.00075 19.3 9.8 0.0019 18.0 9.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 VBB25626.1 - 0.26 11.7 10.3 0.88 10.0 10.3 2.0 1 0 0 1 1 1 0 Ring finger domain ADD_DNMT3 PF17980.1 VBB25626.1 - 2.7 8.0 10.3 1.5 8.9 5.5 2.5 1 1 1 2 2 2 0 Cysteine rich ADD domain in DNMT3 zf-H2C2_5 PF13909.6 VBB25627.1 - 2.4e-13 49.6 13.4 3.5e-07 29.8 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 VBB25627.1 - 1e-06 28.9 22.7 4e-05 23.8 2.5 6.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 VBB25627.1 - 0.24 11.7 23.1 6.2 7.2 0.1 5.4 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 VBB25627.1 - 0.48 11.4 27.7 1.4 9.9 1.1 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 VBB25627.1 - 0.49 10.3 5.2 0.28 11.2 1.1 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Dzip-like_N PF13815.6 VBB25628.1 - 1.4e-12 47.6 0.3 2.1e-12 47.1 0.3 1.2 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal GIT_CC PF16559.5 VBB25628.1 - 0.0084 16.0 1.9 0.013 15.4 1.9 1.3 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 VBB25628.1 - 0.016 15.3 0.4 0.04 14.0 0.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor APC_N_CC PF16689.5 VBB25628.1 - 0.22 11.6 3.4 0.97 9.5 3.4 2.0 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain KCNQ2_u3 PF16642.5 VBB25629.1 - 0.12 13.4 4.0 0.15 13.1 0.1 2.7 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 UBA2_C PF16195.5 VBB25629.1 - 0.94 10.2 8.0 2.5 8.8 0.0 3.0 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus Tmemb_14 PF03647.13 VBB25630.1 - 1.5e-19 70.5 14.1 1.8e-19 70.2 14.1 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF608 PF04685.13 VBB25631.1 - 6.4e-77 259.2 0.5 3.2e-57 194.3 0.0 3.1 1 1 1 2 2 2 2 Glycosyl-hydrolase family 116, catalytic region GDE_C PF06202.14 VBB25631.1 - 0.062 12.2 0.2 0.58 9.0 0.2 1.9 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase RXLR PF16810.5 VBB25631.1 - 0.07 13.6 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Adaptin_N PF01602.20 VBB25632.1 - 6.6e-135 450.6 9.1 9.2e-135 450.1 9.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Myb_DNA-bind_7 PF15963.5 VBB25632.1 - 3.7e-21 74.8 0.3 1.4e-20 73.0 0.3 2.1 1 0 0 1 1 1 1 Myb DNA-binding like Alpha_adaptinC2 PF02883.20 VBB25632.1 - 1.2e-16 61.0 0.4 5.8e-16 58.8 0.4 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 VBB25632.1 - 7.3e-11 42.4 3.5 1.3e-07 31.8 0.3 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Myb_DNA-binding PF00249.31 VBB25632.1 - 0.0095 16.1 0.0 0.044 14.0 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Calponin PF00402.18 VBB25633.1 - 1.6e-22 78.8 2.6 5.9e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Calponin family repeat Myosin_head PF00063.21 VBB25635.1 - 3.8e-175 583.9 2.9 1.6e-123 413.4 0.8 2.4 2 1 1 3 3 3 2 Myosin head (motor domain) Myosin_N PF02736.19 VBB25635.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 VBB25635.1 - 0.0043 17.3 1.3 0.33 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain IQ PF00612.27 VBB25635.1 - 0.0044 16.7 0.4 0.014 15.2 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 VBB25635.1 - 0.01 16.2 0.2 0.076 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain VSG_B PF13206.6 VBB25635.1 - 0.042 13.1 2.2 0.069 12.4 2.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain YtxH PF12732.7 VBB25635.1 - 0.098 13.2 0.5 8.6 7.0 0.5 2.8 1 1 0 1 1 1 0 YtxH-like protein Exonuc_VII_L PF02601.15 VBB25635.1 - 0.16 11.5 6.6 0.35 10.4 6.6 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran PF00005.27 VBB25635.1 - 0.75 10.3 3.8 2.4 8.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Caps_synth_GfcC PF06251.11 VBB25635.1 - 1.3 8.6 4.2 2.6 7.6 4.2 1.5 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Neur_chan_LBD PF02931.23 VBB25636.1 - 8.7e-14 51.5 2.0 1.4e-13 50.8 2.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Tim17 PF02466.19 VBB25637.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Aldo_ket_red PF00248.21 VBB25638.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TetR_C_7 PF14246.6 VBB25638.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain SelP_N PF04592.14 VBB25639.1 - 3.9e-13 49.4 0.0 3.9e-13 49.4 0.0 3.4 3 1 1 4 4 4 1 Selenoprotein P, N terminal region TFIIA PF03153.13 VBB25639.1 - 0.00092 19.3 38.2 0.0017 18.4 38.2 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 VBB25640.1 - 7.2e-23 81.0 5.7 7e-14 52.2 3.0 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 VBB25640.1 - 2.5e-18 65.6 6.1 2.5e-05 24.5 0.2 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 VBB25640.1 - 2.4e-17 61.3 1.9 0.0015 18.9 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 VBB25640.1 - 5.7e-16 58.7 0.4 2.7e-08 34.2 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB25640.1 - 2.7e-14 53.0 7.1 7.4e-05 23.0 0.0 4.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) KN_motif PF12075.8 VBB25640.1 - 0.0044 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 KN motif zf-CCHC PF00098.23 VBB25641.1 - 8.6e-11 41.4 29.6 7.4e-05 22.7 0.5 4.3 4 0 0 4 4 4 4 Zinc knuckle DUF2680 PF10925.8 VBB25641.1 - 1.4e-05 25.0 1.2 3e-05 23.9 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2680) DUF4777 PF16007.5 VBB25641.1 - 0.0026 18.0 0.2 0.034 14.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4777) Comm PF15957.5 VBB25641.1 - 0.069 13.5 0.4 0.14 12.5 0.2 1.6 1 1 0 1 1 1 0 Commissureless Endonuc_BglI PF14562.6 VBB25641.1 - 0.08 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI zf-CCHC_4 PF14392.6 VBB25641.1 - 0.88 9.4 25.6 2.6 7.8 0.4 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-C2H2 PF00096.26 VBB25642.1 - 9.8e-21 73.0 40.8 2.2e-06 27.8 2.4 6.1 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB25642.1 - 2.3e-15 56.2 49.4 1.1e-07 32.0 1.8 6.5 7 1 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB25642.1 - 2.3e-13 49.7 38.2 0.00063 20.4 1.2 5.9 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 VBB25642.1 - 0.0012 18.8 1.1 0.0012 18.8 1.1 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-TRAF PF02176.18 VBB25642.1 - 0.0018 18.9 3.0 0.0018 18.9 3.0 3.0 3 0 0 3 3 2 1 TRAF-type zinc finger NMD3 PF04981.13 VBB25642.1 - 0.0029 17.1 0.1 0.0029 17.1 0.1 2.0 2 1 0 2 2 2 1 NMD3 family zf-C2HC_2 PF13913.6 VBB25642.1 - 0.0053 16.6 17.0 0.27 11.2 0.0 4.9 5 0 0 5 5 4 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 VBB25642.1 - 0.0065 16.7 24.1 0.12 12.7 6.0 4.4 3 2 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 VBB25642.1 - 0.017 15.1 7.0 1.2 9.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-BED PF02892.15 VBB25642.1 - 0.026 14.6 21.9 0.44 10.6 1.9 4.2 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_jaz PF12171.8 VBB25642.1 - 0.11 12.8 23.5 0.42 11.0 0.7 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 VBB25642.1 - 0.2 11.5 0.1 0.2 11.5 0.1 4.0 5 0 0 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 VBB25642.1 - 0.22 11.9 27.0 2.1 8.8 1.4 4.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 VBB25642.1 - 0.22 11.7 4.2 5.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 VBB25642.1 - 0.86 10.0 6.8 6.1 7.2 1.3 3.3 3 0 0 3 3 3 0 zinc-finger-containing domain zf-C2H2_11 PF16622.5 VBB25642.1 - 1.6 8.5 24.2 0.65 9.8 1.8 4.5 5 0 0 5 5 5 0 zinc-finger C2H2-type PyrI_C PF02748.15 VBB25642.1 - 4.6 7.2 14.5 9.1 6.3 0.1 4.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_recom PF13408.6 VBB25642.1 - 5.8 7.5 7.5 29 5.3 0.2 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Cys_rich_CPXG PF14255.6 VBB25642.1 - 6.1 6.8 6.4 8.9 6.3 0.2 3.2 3 0 0 3 3 3 0 Cysteine-rich CPXCG XPA_N PF01286.18 VBB25642.1 - 10 6.3 8.2 6.5 6.9 0.2 3.5 4 0 0 4 4 3 0 XPA protein N-terminal TFIIA PF03153.13 VBB25643.1 - 0.79 9.7 12.5 0.93 9.4 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 7tm_2 PF00002.24 VBB25644.1 - 1.4e-58 198.1 28.3 2.2e-58 197.5 28.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 VBB25644.1 - 8.2e-12 45.5 2.4 8.2e-12 45.5 2.4 3.7 2 1 0 2 2 2 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 VBB25644.1 - 4.4e-11 42.6 3.4 6.8e-11 42.0 3.4 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 VBB25644.1 - 4.7e-08 33.3 0.2 4.7e-08 33.3 0.2 2.6 3 0 0 3 3 3 1 Galactose binding lectin domain Lectin_C PF00059.21 VBB25644.1 - 0.0056 17.4 24.0 0.32 11.7 1.5 5.1 4 1 0 4 4 4 2 Lectin C-type domain Ig_3 PF13927.6 VBB25645.1 - 3.7e-16 59.5 0.1 5.8e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 VBB25645.1 - 3.8e-12 46.1 0.0 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB25645.1 - 3.8e-11 43.2 0.1 7.8e-07 29.3 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 VBB25645.1 - 1.1e-08 35.3 0.1 0.0027 17.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 VBB25645.1 - 2.5e-08 34.0 0.1 0.00025 21.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 VBB25645.1 - 0.0025 17.3 0.1 0.29 10.7 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 VBB25645.1 - 0.033 14.5 0.0 6.8 7.0 0.0 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 VBB25645.1 - 0.048 13.7 0.0 0.54 10.3 0.0 2.5 3 0 0 3 3 3 0 C17orf99 Ig domain Herpes_gE PF02480.16 VBB25645.1 - 0.048 12.4 0.0 1.7 7.3 0.0 2.0 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_5 PF16681.5 VBB25645.1 - 0.052 14.0 0.0 7.2 7.1 0.0 2.6 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Poty_coat PF00767.18 VBB25645.1 - 0.18 11.4 0.0 0.37 10.3 0.0 1.4 1 1 0 1 1 1 0 Potyvirus coat protein Autophagy_act_C PF03987.15 VBB25646.1 - 2.4e-15 56.8 0.2 4.2e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain 7tm_6 PF02949.20 VBB25646.1 - 0.051 12.6 0.4 0.069 12.2 0.4 1.1 1 0 0 1 1 1 0 7tm Odorant receptor PMP22_Claudin PF00822.20 VBB25647.1 - 1.5e-11 44.4 6.2 2.1e-11 44.0 6.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 VBB25647.1 - 0.0011 18.7 21.2 0.0021 17.8 17.2 2.4 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 VBB25647.1 - 0.0027 17.4 7.0 0.0027 17.4 7.0 2.1 1 1 1 2 2 2 1 SUR7/PalI family TMEM37 PF15108.6 VBB25647.1 - 0.022 14.6 4.7 0.046 13.6 4.7 1.5 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Amastin PF07344.11 VBB25647.1 - 0.54 10.1 14.3 2.3 8.1 14.3 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein Synaptobrevin PF00957.21 VBB25647.1 - 0.59 10.0 8.3 1.8 8.4 0.0 2.7 2 1 1 3 3 3 0 Synaptobrevin DUF2417 PF10329.9 VBB25647.1 - 1.2 8.5 7.1 7.3 5.9 0.5 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) PalH PF08733.10 VBB25647.1 - 6.5 5.7 12.3 0.27 10.2 5.4 1.8 1 1 0 2 2 2 0 PalH/RIM21 DUF4231 PF14015.6 VBB25647.1 - 6.9 7.2 6.3 2.6 8.6 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Glyco_transf_10 PF00852.19 VBB25648.1 - 1.2e-47 161.9 3.7 2.6e-47 160.8 3.3 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 VBB25648.1 - 3.7e-16 59.6 0.1 1.2e-15 57.9 0.0 1.8 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal O-ag_pol_Wzy PF14296.6 VBB25648.1 - 0.049 12.3 1.8 0.076 11.6 1.8 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF454 PF04304.13 VBB25648.1 - 0.1 12.6 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF454) G-patch PF01585.23 VBB25649.1 - 6.5e-10 38.7 1.6 1.5e-09 37.6 1.6 1.7 1 1 0 1 1 1 1 G-patch domain Rod_C PF10493.9 VBB25650.1 - 2.2e-21 75.9 13.4 2.2e-21 75.9 13.4 2.4 2 1 0 2 2 2 1 Rough deal protein C-terminal region Pecanex_C PF05041.15 VBB25651.1 - 1e-108 362.2 0.0 1.7e-108 361.5 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) muHD PF10291.9 VBB25652.1 - 2.9e-43 148.2 0.1 5.1e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 VBB25652.1 - 3.6e-08 33.6 0.5 3.6e-08 33.6 0.5 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain YkyA PF10368.9 VBB25652.1 - 0.33 10.6 9.7 0.22 11.2 2.5 2.6 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein GrpE PF01025.19 VBB25652.1 - 0.35 10.5 4.3 1.4 8.6 0.9 3.2 2 1 0 3 3 3 0 GrpE TMCO5 PF14992.6 VBB25652.1 - 0.95 9.0 8.4 0.82 9.2 6.7 1.8 2 0 0 2 2 2 0 TMCO5 family Ctr PF04145.15 VBB25653.1 - 1e-20 74.9 11.9 3.7e-19 69.8 11.9 2.1 1 1 0 1 1 1 1 Ctr copper transporter family TFIIE_alpha PF02002.17 VBB25654.1 - 1.3e-17 63.5 6.3 2e-17 62.9 6.3 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit zf-C2HE PF16278.5 VBB25654.1 - 0.023 15.1 0.4 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 VBB25654.1 - 0.054 13.5 0.8 0.19 11.8 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Pyridoxal_deC PF00282.19 VBB25655.1 - 0.045 12.5 0.0 0.095 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain zf-H2C2_2 PF13465.6 VBB25656.1 - 2.9e-17 62.2 23.3 1.4e-07 31.6 0.2 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 VBB25656.1 - 5.4e-15 54.9 20.3 2.8e-06 27.5 0.5 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB25656.1 - 4.7e-11 42.5 14.5 0.0028 18.3 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.15 VBB25656.1 - 0.012 15.6 5.7 0.04 13.9 1.7 2.9 1 1 1 2 2 2 0 BED zinc finger Zf_RING PF16744.5 VBB25656.1 - 0.015 15.4 1.3 0.74 10.0 0.1 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2HC_2 PF13913.6 VBB25656.1 - 0.019 14.8 10.7 0.36 10.8 0.5 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 VBB25656.1 - 0.026 14.8 4.2 15 6.0 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB25656.1 - 0.064 13.3 5.8 4.3 7.4 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 VBB25656.1 - 0.89 9.9 6.0 10 6.5 5.9 2.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.16 VBB25656.1 - 2.8 8.3 6.2 20 5.6 1.7 3.5 2 1 0 2 2 2 0 C1 domain Thyroglobulin_1 PF00086.18 VBB25657.1 - 7e-61 201.8 24.9 1.1e-11 44.2 0.1 7.4 6 0 0 6 6 6 6 Thyroglobulin type-1 repeat WAP PF00095.21 VBB25657.1 - 5.3e-28 97.1 159.8 4.7e-08 33.3 13.3 22.2 18 5 3 21 21 21 9 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 VBB25657.1 - 2.7e-14 53.2 55.0 7e-07 29.5 10.2 24.0 24 3 1 25 25 25 7 Lustrin, cysteine-rich repeated domain Antistasin PF02822.14 VBB25657.1 - 5.6e-09 36.5 61.9 4.3e-06 27.2 10.1 18.3 19 1 0 19 19 19 7 Antistasin family Sugar_tr PF00083.24 VBB25659.1 - 3.2e-107 359.2 35.4 3.4e-85 286.6 14.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 VBB25659.1 - 7.8e-28 97.4 31.7 4.6e-25 88.3 24.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 VBB25659.1 - 4.5e-05 22.1 1.6 6.9e-05 21.5 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP-gua_Ptrans PF00217.19 VBB25660.1 - 1.1e-59 201.5 0.1 2.1e-59 200.6 0.1 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 VBB25660.1 - 6.4e-23 80.9 0.0 1.3e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain RYDR_ITPR PF01365.21 VBB25661.1 - 7.3e-58 195.3 23.3 3.1e-52 177.0 0.2 5.0 4 1 0 4 4 4 3 RIH domain RIH_assoc PF08454.11 VBB25661.1 - 4e-30 103.7 1.5 4e-30 103.7 1.5 4.8 5 0 0 5 5 5 1 RyR and IP3R Homology associated Ion_trans PF00520.31 VBB25661.1 - 4e-17 62.3 2.8 1.4e-16 60.5 2.7 2.0 1 1 0 1 1 1 1 Ion transport protein MIR PF02815.19 VBB25661.1 - 3.5e-09 36.8 0.1 1.5e-08 34.7 0.1 2.0 2 0 0 2 2 2 1 MIR domain Novirhabdo_Nv PF05554.11 VBB25661.1 - 0.043 13.6 2.2 0.45 10.3 0.1 2.6 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein DUF865 PF05906.11 VBB25663.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Zona_pellucida PF00100.23 VBB25663.1 - 0.13 12.1 0.5 0.17 11.6 0.5 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain Zona_pellucida PF00100.23 VBB25664.1 - 2.4e-10 40.7 0.3 2.9e-10 40.4 0.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Dickkopf_N PF04706.12 VBB25666.1 - 0.0054 17.2 29.3 0.013 15.9 10.0 3.8 3 2 1 4 4 4 2 Dickkopf N-terminal cysteine-rich region DX PF01666.17 VBB25666.1 - 2.4 8.7 38.0 1 9.8 2.5 5.4 2 2 3 5 5 5 0 DX module WAP PF00095.21 VBB25666.1 - 7 7.1 43.1 0.16 12.4 0.7 5.1 4 2 1 5 5 5 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' JmjN PF02375.17 VBB25667.1 - 0.016 15.2 0.0 0.043 13.8 0.0 1.8 1 0 0 1 1 1 0 jmjN domain MBT PF02820.18 VBB25668.1 - 5.2e-35 119.6 1.1 6.1e-19 68.1 0.0 3.7 4 0 0 4 4 4 2 mbt repeat SLED PF12140.8 VBB25668.1 - 1.3e-29 103.0 0.0 3.1e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 VBB25668.1 - 6.5e-05 23.3 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5137 PF17220.3 VBB25668.1 - 0.19 12.6 1.3 0.49 11.3 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) Tex_N PF09371.10 VBB25669.1 - 0.0032 17.2 0.1 0.013 15.2 0.1 1.9 1 1 0 1 1 1 1 Tex-like protein N-terminal domain MnmE_helical PF12631.7 VBB25669.1 - 0.02 15.1 0.5 5.9 7.0 0.1 2.2 2 0 0 2 2 2 0 MnmE helical domain DUF1664 PF07889.12 VBB25669.1 - 0.061 13.4 0.9 1.1 9.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Homeodomain PF00046.29 VBB25670.1 - 3.6e-21 74.8 3.0 3.6e-21 74.8 3.0 1.7 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 VBB25670.1 - 0.00079 18.9 0.5 0.0016 17.8 0.5 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 VBB25670.1 - 0.0048 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain ECSCR PF15820.5 VBB25670.1 - 0.011 15.6 1.1 0.025 14.4 1.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PDZ_3 PF17815.1 VBB25671.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 PDZ domain C2 PF00168.30 VBB25673.1 - 2.7e-58 194.6 0.1 1.2e-30 105.9 0.1 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 VBB25673.1 - 0.0019 17.8 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 CEP76 C2 domain Nucleoside_tran PF01733.18 VBB25673.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoside transporter PTEN_C2 PF10409.9 VBB25673.1 - 0.017 14.9 0.9 5.6 6.7 0.0 3.1 2 1 1 3 3 3 0 C2 domain of PTEN tumour-suppressor protein MFS_1 PF07690.16 VBB25673.1 - 0.047 12.6 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily PMT_2 PF13231.6 VBB25673.1 - 0.073 13.3 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DOCK-C2 PF14429.6 VBB25673.1 - 0.078 12.8 0.0 8.9 6.1 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins DUF2207 PF09972.9 VBB25673.1 - 0.096 11.4 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FeoB_associated PF12669.7 VBB25673.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.0 3 0 0 3 3 2 0 FeoB-associated Cys-rich membrane protein Dodecin PF07311.12 VBB25673.1 - 0.39 11.0 2.0 0.5 10.6 0.1 2.1 1 1 1 2 2 2 0 Dodecin DASH_Hsk3 PF08227.11 VBB25673.1 - 0.82 10.1 2.9 11 6.5 1.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Pkinase PF00069.25 VBB25674.1 - 6.3e-64 215.9 0.0 9.7e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25674.1 - 5.9e-34 117.5 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 VBB25674.1 - 2.2e-07 31.0 0.0 0.012 15.8 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Pkinase_fungal PF17667.1 VBB25674.1 - 4.3e-07 29.1 0.0 6.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 VBB25674.1 - 6.7e-05 22.3 0.0 0.00066 19.1 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 VBB25674.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB25674.1 - 0.0049 16.8 0.1 0.0099 15.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB25674.1 - 0.005 16.5 0.1 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 VBB25674.1 - 0.095 12.3 0.4 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase TF_AP-2 PF03299.14 VBB25675.1 - 1.3e-17 64.5 0.0 2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Transcription factor AP-2 HlyIII PF03006.20 VBB25676.1 - 7.4e-61 205.7 18.7 1e-60 205.3 18.7 1.2 1 0 0 1 1 1 1 Haemolysin-III related SPW PF03779.14 VBB25676.1 - 0.032 13.8 0.2 0.032 13.8 0.2 2.8 2 0 0 2 2 2 0 SPW repeat DUF962 PF06127.11 VBB25676.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4131 PF13567.6 VBB25676.1 - 4 7.1 13.5 4.7 6.8 0.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) JAB PF01398.21 VBB25681.1 - 2.1e-18 66.4 0.1 6.2e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 VBB25681.1 - 4.8e-16 59.0 1.3 8.2e-16 58.2 1.3 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 VBB25681.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Metallophos PF00149.28 VBB25682.1 - 4.5e-13 50.2 0.2 8.4e-13 49.3 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB25682.1 - 2.7e-06 27.7 0.0 5.6e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2065 PF09838.9 VBB25682.1 - 0.00078 19.4 2.4 0.0035 17.3 0.6 2.5 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2065) GST_N PF02798.20 VBB25683.1 - 5.6e-11 42.6 0.0 9.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 VBB25683.1 - 1e-07 32.3 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 VBB25683.1 - 0.0027 18.0 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 VBB25683.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 VBB25683.1 - 0.021 15.5 0.0 0.028 15.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 VBB25683.1 - 0.085 13.1 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin Mito_carr PF00153.27 VBB25684.1 - 3.2e-61 203.3 2.5 1.5e-20 72.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M1 PF01433.20 VBB25685.1 - 5e-51 173.4 1.2 8.9e-51 172.5 1.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain COPIIcoated_ERV PF07970.12 VBB25685.1 - 5.2e-26 91.9 0.1 5.2e-26 91.9 0.1 2.4 3 0 0 3 3 3 1 Endoplasmic reticulum vesicle transporter Peptidase_M1_N PF17900.1 VBB25685.1 - 2.4e-20 73.5 0.2 1.7e-19 70.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERGIC_N PF13850.6 VBB25685.1 - 3.1e-11 43.5 0.0 1.1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ERAP1_C PF11838.8 VBB25685.1 - 9.3e-07 28.7 1.1 1.9e-06 27.6 0.6 1.9 2 1 0 2 2 2 1 ERAP1-like C-terminal domain DUF1570 PF07607.11 VBB25685.1 - 0.053 13.8 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) Peptidase_M61 PF05299.12 VBB25685.1 - 0.056 13.8 1.4 0.85 10.0 1.4 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ras PF00071.22 VBB25686.1 - 3.6e-51 173.0 0.4 6.2e-51 172.2 0.4 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB25686.1 - 3.1e-31 108.1 0.2 3.1e-31 108.1 0.2 2.1 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB25686.1 - 6.5e-15 55.0 0.0 1.9e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB25686.1 - 9.5e-06 25.1 0.3 9.5e-06 25.1 0.3 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB25686.1 - 1e-05 25.6 0.1 4.6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 VBB25686.1 - 0.00071 19.2 0.1 0.00071 19.2 0.1 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.6 VBB25686.1 - 0.0039 17.6 0.2 0.017 15.6 0.2 2.2 1 0 0 1 1 1 1 EF-hand domain pair SRPRB PF09439.10 VBB25686.1 - 0.036 13.5 0.5 0.11 11.9 0.1 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit EF-hand_6 PF13405.6 VBB25686.1 - 4.8 7.4 9.2 10 6.3 0.0 4.0 5 0 0 5 5 5 0 EF-hand domain Patched PF02460.18 VBB25687.1 - 3.2e-207 690.4 14.2 4.1e-207 690.0 14.2 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB25687.1 - 4.5e-28 98.0 4.1 4.5e-28 98.0 4.1 3.1 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 VBB25687.1 - 0.3 8.7 12.8 0.6 7.7 12.8 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family EMC3_TMCO1 PF01956.16 VBB25689.1 - 3.2e-53 180.0 0.4 3.2e-53 180.0 0.4 2.1 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like CotH PF08757.11 VBB25689.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 CotH kinase protein PTP_tm PF18861.1 VBB25689.1 - 0.19 11.7 0.0 0.51 10.3 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Prefoldin PF02996.17 VBB25690.1 - 4.2e-14 52.5 0.6 7.2e-14 51.7 0.5 1.5 1 1 0 1 1 1 1 Prefoldin subunit Phosducin PF02114.16 VBB25691.1 - 4e-30 104.7 0.5 3.8e-25 88.3 0.1 2.3 1 1 1 2 2 2 2 Phosducin Thioredoxin PF00085.20 VBB25691.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin NPR3 PF03666.13 VBB25692.1 - 4.3e-29 101.6 4.2 2.4e-24 86.0 3.4 3.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Pyr_redox_2 PF07992.14 VBB25693.1 - 1.4e-11 44.2 0.9 3.5e-08 33.1 0.0 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rpp20 PF12328.8 VBB25694.1 - 1.3e-14 54.3 2.6 1.1e-11 44.9 0.5 2.2 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 VBB25694.1 - 9e-13 47.8 0.2 2.6e-12 46.4 0.3 1.7 1 1 1 2 2 2 1 Alba DegV PF02645.16 VBB25694.1 - 0.014 14.7 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 Calici_MSP PF05752.11 VBB25694.1 - 0.034 14.0 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Calicivirus minor structural protein WD40 PF00400.32 VBB25695.1 - 1.4e-06 28.9 0.4 0.12 13.3 0.0 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB25695.1 - 0.00013 22.2 0.0 0.37 11.1 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3512 PF12024.8 VBB25696.1 - 1.2e-52 178.8 0.0 1.2e-52 178.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 VBB25696.1 - 9.1e-22 76.9 0.5 3.8e-21 75.0 0.3 2.2 2 0 0 2 2 2 1 Bromodomain CDC27 PF09507.10 VBB25696.1 - 0.021 14.2 13.2 0.033 13.6 13.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ABC_membrane PF00664.23 VBB25697.1 - 9.1e-59 199.3 15.1 1.6e-58 198.6 15.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 VBB25697.1 - 2e-32 112.5 0.0 6.9e-32 110.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 VBB25697.1 - 8.6e-12 45.0 2.9 1.6e-09 37.6 2.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 VBB25697.1 - 0.0091 15.9 0.1 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 VBB25697.1 - 0.016 15.6 0.3 0.12 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 VBB25697.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_PrkA PF08298.11 VBB25697.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain IstB_IS21 PF01695.17 VBB25697.1 - 0.071 12.8 0.2 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 VBB25697.1 - 0.095 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 VBB25697.1 - 0.12 12.4 0.1 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 VBB25697.1 - 0.14 12.4 0.3 1.5 9.1 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 VBB25697.1 - 0.21 12.1 0.3 1.7 9.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain DOT1 PF08123.13 VBB25698.1 - 1.7e-61 207.4 2.2 3.9e-61 206.2 0.0 2.1 2 0 0 2 2 2 1 Histone methylation protein DOT1 bZIP_1 PF00170.21 VBB25698.1 - 0.09 12.9 8.0 11 6.2 0.1 4.2 3 0 0 3 3 3 0 bZIP transcription factor Methyltransf_4 PF02390.17 VBB25698.1 - 0.13 11.7 0.6 0.52 9.8 0.0 2.4 3 0 0 3 3 3 0 Putative methyltransferase HALZ PF02183.18 VBB25698.1 - 3.4 8.0 5.7 21 5.5 0.4 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ctf8 PF09696.10 VBB25700.1 - 2.7e-09 37.5 4.7 1.7e-05 25.2 2.1 3.0 1 1 1 2 2 2 2 Ctf8 Leo1 PF04004.13 VBB25700.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Leo1-like protein Ge1_WD40 PF16529.5 VBB25701.1 - 2.1e-53 181.4 0.7 3.4e-53 180.7 0.7 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 VBB25701.1 - 0.003 17.8 0.1 0.62 10.4 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Sec7_N PF12783.7 VBB25701.1 - 0.72 9.7 8.4 0.031 14.2 1.9 2.1 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PhoLip_ATPase_C PF16212.5 VBB25702.1 - 2.2e-50 171.8 39.7 4.3e-50 170.8 30.2 3.1 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 VBB25702.1 - 2.3e-13 50.9 1.1 8.1e-06 26.3 0.1 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 VBB25702.1 - 6.2e-12 45.4 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 VBB25702.1 - 6e-05 22.9 0.1 0.00024 20.9 0.1 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB25702.1 - 0.024 15.1 0.1 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase CotJB PF12652.7 VBB25702.1 - 0.19 12.0 0.1 0.85 9.9 0.0 2.1 2 0 0 2 2 2 0 CotJB protein E1-E2_ATPase PF00122.20 VBB25702.1 - 0.39 10.2 0.0 0.39 10.2 0.0 4.0 3 1 1 4 4 4 0 E1-E2 ATPase RRM_1 PF00076.22 VBB25703.1 - 8.4e-23 80.0 0.1 3.7e-06 26.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LCM PF04072.14 VBB25705.1 - 7.7e-30 104.2 0.0 1.4e-29 103.4 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase BsuBI_PstI_RE PF06616.11 VBB25705.1 - 0.055 12.8 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain Methyltransf_25 PF13649.6 VBB25706.1 - 0.0009 19.9 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB25706.1 - 0.0011 19.6 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB25706.1 - 0.0023 17.8 0.1 0.0059 16.4 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 VBB25706.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Met_10 PF02475.16 VBB25706.1 - 0.046 13.5 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein A2M PF00207.22 VBB25707.1 - 3e-12 46.2 0.4 1.1e-11 44.4 0.4 2.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 VBB25707.1 - 3e-08 34.1 0.0 1.2e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain Synaptobrevin PF00957.21 VBB25709.1 - 6.9e-21 73.8 1.1 7.6e-21 73.7 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 VBB25709.1 - 4.7e-05 23.6 0.2 5.6e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Laminin_I PF06008.14 VBB25709.1 - 0.026 14.3 0.1 0.033 13.9 0.1 1.0 1 0 0 1 1 1 0 Laminin Domain I Ran-binding PF05508.11 VBB25709.1 - 0.075 12.0 0.2 0.085 11.8 0.2 1.1 1 0 0 1 1 1 0 RanGTP-binding protein EMP24_GP25L PF01105.24 VBB25709.1 - 0.35 10.8 3.8 0.94 9.4 3.8 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD XhlA PF10779.9 VBB25709.1 - 0.38 11.0 0.3 0.38 11.0 0.3 2.5 2 1 1 3 3 3 0 Haemolysin XhlA Fzo_mitofusin PF04799.13 VBB25709.1 - 0.42 10.1 6.4 0.072 12.6 0.8 1.9 1 1 1 2 2 2 0 fzo-like conserved region TRM13 PF05206.14 VBB25711.1 - 5.4e-47 160.5 0.3 9.2e-47 159.8 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 Med31 PF05669.12 VBB25711.1 - 7.1e-35 118.9 8.8 2.7e-34 117.1 8.8 2.1 1 0 0 1 1 1 1 SOH1 DUF3456 PF11938.8 VBB25711.1 - 2.4e-26 93.1 6.9 2.4e-26 93.1 6.9 2.2 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP zf-TRM13_CCCH PF11722.8 VBB25711.1 - 2.1e-09 37.0 8.7 2.1e-09 37.0 8.7 3.4 4 0 0 4 4 4 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 VBB25711.1 - 2.9e-07 30.2 2.5 7.9e-07 28.9 2.5 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 VBB25711.1 - 0.039 13.9 3.6 0.056 13.4 0.8 2.5 2 1 0 2 2 2 0 Methyltransferase domain zf-TRAF PF02176.18 VBB25711.1 - 0.066 13.9 3.1 0.14 12.8 0.3 3.0 2 0 0 2 2 2 0 TRAF-type zinc finger DUF3854 PF12965.7 VBB25712.1 - 0.095 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) BRE1 PF08647.11 VBB25713.1 - 0.011 15.8 8.0 0.011 15.8 8.0 4.2 3 2 2 5 5 5 0 BRE1 E3 ubiquitin ligase Shugoshin_N PF07558.11 VBB25713.1 - 0.014 15.2 8.1 0.031 14.2 2.8 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region GrpE PF01025.19 VBB25713.1 - 0.045 13.4 0.6 0.045 13.4 0.6 3.4 3 1 1 4 4 4 0 GrpE DUF4931 PF16285.5 VBB25713.1 - 0.05 12.9 0.6 0.097 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) Fez1 PF06818.15 VBB25713.1 - 0.25 11.8 26.7 0.061 13.8 17.5 2.6 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 VBB25713.1 - 0.85 9.8 33.6 0.25 11.6 1.0 4.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 VBB25713.1 - 1.7 8.8 21.4 0.9 9.7 14.8 2.7 2 1 0 2 2 2 0 Tropomyosin like FUSC PF04632.12 VBB25713.1 - 2.4 6.6 6.0 1.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family HAP1_N PF04849.13 VBB25713.1 - 5.7 6.0 25.6 4.2 6.5 7.8 3.2 1 1 2 3 3 3 0 HAP1 N-terminal conserved region ERM PF00769.19 VBB25713.1 - 7.7 6.2 29.2 0.78 9.5 15.1 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PI3K_P85_iSH2 PF16454.5 VBB25713.1 - 9 5.9 21.0 0.72 9.4 12.5 2.9 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EBP PF05241.12 VBB25714.1 - 7.9e-08 32.0 6.6 9.8e-08 31.7 6.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein BTB PF00651.31 VBB25715.1 - 9.3e-05 22.6 0.1 0.00028 21.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain MIT_C PF16565.5 VBB25715.1 - 0.017 15.1 0.9 0.048 13.7 0.9 1.7 1 1 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Laminin_EGF PF00053.24 VBB25715.1 - 0.08 13.1 5.2 0.17 12.0 5.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain zf-CRD PF17979.1 VBB25715.1 - 0.24 11.5 9.0 0.11 12.6 5.6 2.0 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-AN1 PF01428.16 VBB25715.1 - 0.33 11.2 6.6 0.76 10.0 6.6 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger C5HCH PF17982.1 VBB25715.1 - 1.5 9.1 10.7 0.096 12.9 5.1 1.9 2 0 0 2 2 2 0 NSD Cys-His rich domain Kinesin PF00225.23 VBB25716.1 - 3.3e-112 374.7 0.0 5.1e-112 374.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 VBB25716.1 - 4.3e-52 176.9 4.5 3.4e-43 147.9 0.3 2.9 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 VBB25716.1 - 1.6e-36 126.3 0.0 4.9e-36 124.7 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 VBB25716.1 - 5e-25 88.2 0.1 1.7e-24 86.4 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 VBB25716.1 - 4.3e-11 43.1 6.1 3.8e-10 40.0 2.7 2.9 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 VBB25716.1 - 8.4e-10 39.1 0.1 6.9e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 VBB25716.1 - 0.041 14.3 0.9 0.12 12.8 0.1 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain Ribosomal_S13_N PF08069.12 VBB25716.1 - 0.055 13.5 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_11 PF13086.6 VBB25716.1 - 8.3 6.1 7.2 0.83 9.4 0.5 2.3 2 0 0 2 2 2 0 AAA domain ASF1_hist_chap PF04729.13 VBB25717.1 - 9e-61 204.3 0.1 3e-60 202.7 0.0 1.7 2 0 0 2 2 2 1 ASF1 like histone chaperone Ank_2 PF12796.7 VBB25720.1 - 1.6e-32 111.9 3.2 2.5e-07 31.2 0.2 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 VBB25720.1 - 9.6e-27 92.2 2.8 5.7e-06 26.5 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 VBB25720.1 - 4.5e-26 90.6 3.8 4.8e-10 39.5 0.0 6.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB25720.1 - 1.3e-25 86.6 2.7 0.00049 20.3 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 VBB25720.1 - 1.6e-25 89.1 1.0 2.3e-13 50.4 0.1 5.9 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Notch PF00066.17 VBB25721.1 - 3.2e-18 65.9 46.8 9.2e-09 35.6 9.8 6.4 6 0 0 6 6 6 3 LNR domain EGF PF00008.27 VBB25721.1 - 3.3e-12 46.5 36.3 4.2e-06 26.9 8.3 9.4 11 0 0 11 11 11 5 EGF-like domain hEGF PF12661.7 VBB25721.1 - 7.7e-07 29.5 75.2 0.0014 19.1 4.3 8.2 7 0 0 7 7 7 4 Human growth factor-like EGF EGF_CA PF07645.15 VBB25721.1 - 6.6e-06 26.2 11.9 6.6e-06 26.2 11.9 8.1 5 2 2 7 7 7 1 Calcium-binding EGF domain DUF2853 PF11015.8 VBB25721.1 - 0.051 14.3 0.2 0.14 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) NOD PF06816.13 VBB25721.1 - 0.056 13.1 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 NOTCH protein CD20 PF04103.15 VBB25722.1 - 6.4e-05 23.1 7.0 6.4e-05 23.1 7.0 2.2 1 1 1 2 2 2 2 CD20-like family DUF308 PF03729.13 VBB25722.1 - 0.00053 20.3 6.7 0.00053 20.3 6.7 2.1 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) 7TMR-DISM_7TM PF07695.11 VBB25722.1 - 0.01 15.8 9.1 0.01 15.8 9.1 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Bac_rhodopsin PF01036.18 VBB25722.1 - 0.025 14.1 2.1 0.031 13.9 2.1 1.2 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein TMEM100 PF16311.5 VBB25722.1 - 0.3 10.7 4.4 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 PXA PF02194.15 VBB25723.1 - 4.1e-47 160.5 1.5 1e-46 159.2 0.8 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 VBB25723.1 - 4.5e-26 91.6 0.7 1.5e-25 90.0 0.3 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 VBB25723.1 - 7.6e-15 54.9 0.0 2.1e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 VBB25723.1 - 1.7e-11 44.4 0.0 6.1e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kelch_5 PF13854.6 VBB25724.1 - 9.7e-20 70.1 4.7 1.8e-05 24.6 0.2 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 VBB25724.1 - 1.9e-18 66.3 11.8 6.1e-07 29.6 0.0 5.4 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 VBB25724.1 - 6.5e-15 54.8 4.6 0.003 17.8 0.1 6.6 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 VBB25724.1 - 4.6e-14 52.2 2.2 6.4e-09 35.7 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 VBB25724.1 - 1.1e-12 47.3 3.1 0.0072 15.9 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 VBB25724.1 - 1.6e-11 43.7 2.7 0.033 14.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Fibrinogen_C PF00147.18 VBB25725.1 - 2.8e-19 69.8 0.1 5.1e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Ldl_recept_a PF00057.18 VBB25725.1 - 1.6e-09 37.8 34.2 1.8e-05 24.8 6.5 4.8 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Peroxin-13_N PF04088.13 VBB25726.1 - 1.9e-20 73.6 4.2 5.9e-20 72.0 4.2 1.7 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 VBB25726.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 VBB25726.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Phage_holin_7_1 PF16081.5 VBB25726.1 - 0.042 14.0 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family SH3_1 PF00018.28 VBB25726.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.8 1 1 0 1 1 1 0 SH3 domain Homeodomain PF00046.29 VBB25727.1 - 2e-20 72.4 3.6 3.2e-20 71.7 3.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB25727.1 - 0.035 14.0 0.8 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Homeobox KN domain GST_N_4 PF17172.4 VBB25728.1 - 2e-18 67.0 0.1 3.9e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 VBB25728.1 - 8.6e-15 54.3 0.0 1.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 VBB25728.1 - 3.3e-09 36.6 0.0 8.7e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 VBB25728.1 - 0.00023 21.3 0.1 0.0038 17.4 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 VBB25728.1 - 0.00052 20.3 0.0 0.00086 19.6 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 VBB25728.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 VBB25728.1 - 0.018 15.4 0.0 0.094 13.1 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SHR-BD PF06650.12 VBB25729.1 - 2.5e-60 204.1 0.3 1.3e-54 185.4 0.1 3.2 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 VBB25729.1 - 3e-50 171.2 1.4 3.8e-49 167.6 2.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 VBB25729.1 - 1.2e-25 89.9 4.4 2.8e-15 56.4 0.3 3.7 3 0 0 3 3 3 2 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 VBB25729.1 - 6.5e-13 48.8 5.6 5.9e-10 39.2 0.1 3.6 2 1 1 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Myco_19_kDa PF05481.12 VBB25729.1 - 0.14 12.4 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen E1_DerP2_DerF2 PF02221.15 VBB25730.1 - 3.8e-13 50.0 0.1 4.3e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 ML domain MMR_HSR1 PF01926.23 VBB25731.1 - 4.5e-18 65.4 0.1 2.1e-14 53.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 VBB25731.1 - 1.1e-16 60.6 23.7 1.1e-16 60.6 23.7 4.4 4 0 0 4 4 4 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 VBB25731.1 - 2.7e-11 43.2 0.4 2.4e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 VBB25731.1 - 0.00014 21.8 3.1 0.23 11.4 0.0 3.3 2 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 VBB25731.1 - 0.00034 20.2 1.0 0.0038 16.8 0.0 3.1 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 VBB25731.1 - 0.0086 16.2 0.0 0.0086 16.2 0.0 4.8 5 1 1 6 6 6 2 Dynamin family ABC_tran PF00005.27 VBB25731.1 - 0.07 13.6 4.8 7.5 7.1 0.0 3.9 4 0 0 4 4 4 0 ABC transporter Cys_rich_FGFR PF00839.17 VBB25732.1 - 3.7e-144 468.9 90.4 2.5e-15 56.4 1.8 16.3 15 1 1 16 16 16 16 Cysteine rich repeat Spc7 PF08317.11 VBB25733.1 - 0.0031 16.4 5.7 0.0039 16.1 5.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Fib_alpha PF08702.10 VBB25733.1 - 0.0031 17.7 4.7 0.0044 17.2 4.7 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PLU-1 PF08429.11 VBB25733.1 - 0.0032 16.7 2.9 0.0045 16.2 2.9 1.3 1 1 0 1 1 1 1 PLU-1-like protein APG17 PF04108.12 VBB25733.1 - 0.0033 16.6 3.0 0.0039 16.4 3.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DASH_Spc19 PF08287.11 VBB25733.1 - 0.0086 16.0 3.0 0.011 15.6 3.0 1.1 1 0 0 1 1 1 1 Spc19 Com_YlbF PF06133.11 VBB25733.1 - 0.0088 16.6 8.2 0.02 15.5 8.1 1.6 1 1 0 1 1 1 1 Control of competence regulator ComK, YlbF/YmcA Serine_rich PF08824.10 VBB25733.1 - 0.02 14.9 0.4 0.023 14.7 0.4 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF913 PF06025.12 VBB25733.1 - 0.025 13.6 0.5 0.032 13.2 0.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cauli_AT PF03233.13 VBB25733.1 - 0.029 14.3 5.1 0.057 13.3 5.0 1.4 1 1 0 1 1 1 0 Aphid transmission protein ISG65-75 PF11727.8 VBB25733.1 - 0.074 12.3 5.4 0.095 11.9 5.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein PSDC PF12588.8 VBB25733.1 - 0.089 12.8 1.5 0.2 11.6 0.8 1.7 1 1 1 2 2 2 0 Phophatidylserine decarboxylase DUF4279 PF14106.6 VBB25733.1 - 0.092 13.0 1.4 0.99 9.6 0.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4279) Sec8_exocyst PF04048.14 VBB25733.1 - 0.1 12.5 3.6 0.22 11.4 3.6 1.7 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain FliD_N PF02465.18 VBB25733.1 - 0.13 13.0 2.9 0.18 12.6 2.9 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Ribonuc_red_lgN PF00317.21 VBB25733.1 - 0.19 11.7 0.7 0.51 10.4 0.1 1.8 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain LUC7 PF03194.15 VBB25733.1 - 0.31 10.7 9.9 0.67 9.6 9.9 1.5 1 1 0 1 1 1 0 LUC7 N_terminus Snapin_Pallidin PF14712.6 VBB25733.1 - 1.3 9.5 8.4 6.4 7.3 1.7 2.2 1 1 1 2 2 2 0 Snapin/Pallidin TMPIT PF07851.13 VBB25733.1 - 1.3 8.2 6.0 1.9 7.7 6.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein UQ_con PF00179.26 VBB25734.1 - 1.3e-33 115.6 0.0 1.6e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB25734.1 - 2.7e-06 27.1 0.2 7e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic E2 family B UFC1 PF08694.11 VBB25734.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 VBB25734.1 - 0.083 13.2 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Tmemb_18A PF09771.9 VBB25735.1 - 3.1e-24 85.6 0.0 4.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 188 PQ-loop PF04193.14 VBB25736.1 - 3e-24 84.6 3.4 3.3e-14 52.4 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat TatC PF00902.18 VBB25736.1 - 0.13 12.1 4.1 0.26 11.1 4.1 1.4 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) TspO_MBR PF03073.15 VBB25736.1 - 4.6 7.3 8.7 0.31 11.1 3.3 1.9 2 1 0 2 2 2 0 TspO/MBR family Filamin PF00630.19 VBB25737.1 - 9.1e-127 415.1 10.3 2e-15 57.5 0.2 14.2 13 1 0 13 13 13 13 Filamin/ABP280 repeat CH PF00307.31 VBB25737.1 - 1.1e-33 115.6 1.1 4.9e-17 62.1 0.9 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 VBB25737.1 - 2e-07 30.9 7.5 0.85 9.6 0.0 6.5 8 0 0 8 8 8 3 Y_Y_Y domain Invasin_D3 PF09134.10 VBB25737.1 - 9.2e-07 29.1 0.8 0.074 13.4 0.0 5.8 6 0 0 6 6 6 2 Invasin, domain 3 MG4 PF17789.1 VBB25737.1 - 0.001 19.2 0.1 9 6.5 0.0 4.5 3 1 1 4 4 4 2 Macroglobulin domain MG4 DUF5060 PF16586.5 VBB25737.1 - 0.035 14.5 0.0 9 6.8 0.0 4.6 6 0 0 6 6 6 0 Domain of unknown function (DUF5060) CAMSAP_CH PF11971.8 VBB25737.1 - 0.04 13.7 0.0 20 5.1 0.0 3.2 3 0 0 3 3 3 0 CAMSAP CH domain DUF4198 PF10670.9 VBB25737.1 - 0.056 13.8 0.1 1.8 8.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4198) PapC_N PF13954.6 VBB25737.1 - 0.12 12.4 0.0 14 5.6 0.0 4.0 4 0 0 4 4 4 0 PapC N-terminal domain Big_3_5 PF16640.5 VBB25737.1 - 0.46 10.7 2.9 1.6e+02 2.6 0.0 5.3 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 3) Peptidase_M14 PF00246.24 VBB25738.1 - 1.6e-77 261.2 0.1 6.9e-76 255.8 0.0 2.2 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 VBB25738.1 - 1.9e-15 56.9 0.2 6.8e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 VBB25738.1 - 2.3e-05 24.3 0.6 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 2 CarboxypepD_reg-like domain LTV PF04180.14 VBB25739.1 - 4.7e-20 72.7 32.6 7.7e-11 42.3 7.5 3.5 1 1 2 3 3 3 2 Low temperature viability protein Herpes_UL56 PF04534.12 VBB25739.1 - 0.2 11.1 0.6 0.31 10.5 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein MPM1 PF17234.2 VBB25739.1 - 2.9 8.1 9.5 3.1 8.0 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Pkinase PF00069.25 VBB25740.1 - 8e-60 202.4 0.0 1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25740.1 - 3.4e-36 124.9 0.0 1.5e-35 122.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25740.1 - 0.00011 21.2 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 VBB25740.1 - 0.00086 18.3 0.2 0.0012 17.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 VBB25740.1 - 0.0012 18.0 0.6 0.0018 17.4 0.6 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 VBB25740.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 VBB25740.1 - 0.55 9.8 1.9 0.58 9.7 0.0 1.9 3 0 0 3 3 3 0 RIO1 family FragX_IP PF05994.11 VBB25741.1 - 0 1066.4 7.1 0 1016.9 0.9 2.6 2 1 1 3 3 3 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 VBB25741.1 - 1.6e-11 44.0 5.4 4.3e-11 42.6 5.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Tnp_22_trimer PF17489.2 VBB25741.1 - 0.072 13.1 0.2 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 L1 transposable element trimerization domain Baculo_PEP_C PF04513.12 VBB25741.1 - 1.1 9.3 7.0 2.9 7.9 1.9 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NBD94 PF16830.5 VBB25741.1 - 1.2 9.6 6.0 1.6 9.2 1.1 3.4 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH RRM_1 PF00076.22 VBB25742.1 - 2.7e-16 59.1 0.0 0.00046 19.9 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.31 VBB25744.1 - 1.2e-23 83.4 0.6 1.4e-22 80.0 0.4 2.4 1 1 1 2 2 2 1 BTB/POZ domain PAP_assoc PF03828.19 VBB25744.1 - 1e-12 48.0 0.0 2.7e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 VBB25744.1 - 7.7e-10 38.9 0.6 5.1e-09 36.3 0.1 2.4 2 1 0 2 2 2 1 Nucleotidyltransferase domain MATH PF00917.26 VBB25744.1 - 0.0064 16.6 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 MATH domain Collagen PF01391.18 VBB25745.1 - 7.3e-12 44.9 37.3 9e-10 38.2 37.3 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Presenilin PF01080.17 VBB25746.1 - 8.3e-89 298.1 4.3 9.6e-89 297.9 4.3 1.0 1 0 0 1 1 1 1 Presenilin DUF4728 PF15860.5 VBB25746.1 - 0.52 11.0 17.4 6.1 7.6 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4728) Asp4 PF16996.5 VBB25746.1 - 1.4 8.8 4.2 33 4.4 0.2 3.6 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 DUF3852 PF12963.7 VBB25746.1 - 9.5 6.6 10.7 0.81 10.1 4.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3852) DARPP-32 PF05395.12 VBB25747.1 - 1.4 9.1 11.3 2.6 8.2 3.0 2.9 2 1 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 SIX1_SD PF16878.5 VBB25748.1 - 2.9e-45 153.3 0.2 2.9e-45 153.3 0.2 2.5 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 VBB25748.1 - 2.8e-12 46.3 1.0 2.8e-12 46.3 1.0 2.5 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 VBB25748.1 - 2.2e-10 40.3 0.2 4.7e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 VBB25748.1 - 0.03 13.8 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez FAM163 PF15069.6 VBB25750.1 - 0.012 16.1 3.4 0.021 15.2 3.4 1.4 1 0 0 1 1 1 0 FAM163 family CCER1 PF15482.6 VBB25750.1 - 0.013 15.4 0.4 0.02 14.8 0.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Shisa PF13908.6 VBB25750.1 - 0.025 14.8 6.8 0.026 14.8 5.8 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Comm PF15957.5 VBB25750.1 - 0.051 13.9 0.6 0.094 13.1 0.6 1.4 1 0 0 1 1 1 0 Commissureless cwf18 PF08315.12 VBB25750.1 - 0.074 13.7 0.3 0.11 13.2 0.3 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor TcpE PF12648.7 VBB25750.1 - 0.13 12.9 0.9 4.4 7.9 0.1 2.4 3 0 0 3 3 3 0 TcpE family Corona_S2 PF01601.16 VBB25750.1 - 0.19 10.2 3.5 0.29 9.6 3.5 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF3149 PF11346.8 VBB25750.1 - 0.39 10.4 5.5 1.9 8.2 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3149) Prominin PF05478.11 VBB25750.1 - 4.1 5.2 8.9 5.8 4.7 8.9 1.1 1 0 0 1 1 1 0 Prominin IP_trans PF02121.18 VBB25751.1 - 1.3e-95 319.7 2.5 1.5e-95 319.5 2.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF2484 PF10658.9 VBB25752.1 - 0.11 12.8 1.4 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) Mt_ATP-synt_B PF05405.14 VBB25754.1 - 3e-18 66.0 5.2 4.2e-18 65.5 5.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ETC_C1_NDUFA5 PF04716.14 VBB25754.1 - 0.15 11.9 0.9 0.32 10.8 0.9 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region ChaB PF06150.12 VBB25754.1 - 0.81 10.3 8.4 2.1 9.0 6.9 2.4 2 1 0 2 2 2 0 ChaB XAP5 PF04921.14 VBB25755.1 - 1.9e-65 221.2 4.6 1.9e-65 221.2 4.6 2.3 1 1 1 2 2 2 1 XAP5, circadian clock regulator YnfE PF17452.2 VBB25755.1 - 0.37 11.1 2.9 0.93 9.8 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized YnfE-like TBCC_N PF16752.5 VBB25755.1 - 4.1 7.9 10.8 0.12 12.8 3.4 2.2 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF4706 PF15797.5 VBB25755.1 - 5.3 7.6 6.4 0.69 10.5 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4706) Cwf_Cwc_15 PF04889.12 VBB25756.1 - 1.6e-67 227.8 25.2 8.5e-44 150.1 13.4 2.1 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein DUF4407 PF14362.6 VBB25756.1 - 0.45 9.8 6.7 0.58 9.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AID PF18767.1 VBB25760.1 - 0.023 14.7 0.1 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 Activation induced deaminase Cystatin PF00031.21 VBB25761.1 - 1.2e-12 47.9 0.1 1.6e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Cystatin domain Mpp10 PF04006.12 VBB25761.1 - 0.031 12.7 0.0 0.036 12.5 0.0 1.1 1 0 0 1 1 1 0 Mpp10 protein TTRAP PF14203.6 VBB25761.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Malic_M PF03949.15 VBB25762.1 - 6.5e-90 300.9 0.0 8.3e-90 300.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 VBB25762.1 - 5.6e-64 215.3 0.0 9.3e-64 214.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MtN3_slv PF03083.16 VBB25763.1 - 1.2e-14 54.1 17.3 1.5e-07 31.4 1.3 2.8 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange Glyoxalase PF00903.25 VBB25764.1 - 5.5e-16 58.9 0.1 6.1e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 VBB25764.1 - 2.5e-12 47.0 0.0 2.9e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 VBB25764.1 - 0.0057 16.8 0.0 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 VBB25764.1 - 0.12 12.5 0.0 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain DUF1077 PF06417.12 VBB25765.1 - 4.8e-47 158.8 5.4 6.2e-47 158.5 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) AAA PF00004.29 VBB25766.1 - 2.3e-42 144.6 0.0 3.7e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB25766.1 - 1.3e-08 34.5 0.1 8.4e-08 31.9 0.0 2.3 3 0 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 VBB25766.1 - 1.2e-05 25.8 0.1 0.00044 20.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 VBB25766.1 - 1.3e-05 25.5 0.0 0.0032 17.7 0.0 3.2 1 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 VBB25766.1 - 0.00082 19.4 0.3 0.02 14.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 VBB25766.1 - 0.00084 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 VBB25766.1 - 0.00091 19.2 0.1 0.062 13.2 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_14 PF13173.6 VBB25766.1 - 0.003 17.6 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 VBB25766.1 - 0.0089 16.4 0.0 0.026 14.9 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Rad17 PF03215.15 VBB25766.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 VBB25766.1 - 0.015 15.0 0.0 0.12 12.1 0.0 2.5 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 VBB25766.1 - 0.017 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 VBB25766.1 - 0.021 15.4 0.0 0.084 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 VBB25766.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 VBB25766.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_33 PF13671.6 VBB25766.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 VBB25766.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 VBB25766.1 - 0.081 12.1 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 VBB25766.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 VBB25766.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CRAL_TRIO PF00650.20 VBB25767.1 - 5.2e-21 75.0 0.3 9.2e-21 74.2 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 VBB25767.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PEX-1N PF09262.11 VBB25768.1 - 1.9e-11 44.2 0.1 4.6e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA PF00004.29 VBB25768.1 - 1.5e-07 31.9 0.0 4.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB25768.1 - 2.4e-05 24.8 0.7 0.0063 16.9 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 VBB25768.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB25768.1 - 0.016 15.8 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 VBB25768.1 - 0.018 14.2 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 VBB25768.1 - 0.019 15.2 0.2 0.08 13.2 0.1 1.9 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 VBB25768.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 VBB25768.1 - 0.045 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DHC_N2 PF08393.13 VBB25768.1 - 0.074 12.1 1.2 0.14 11.2 0.3 1.9 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 AAA_22 PF13401.6 VBB25768.1 - 0.086 13.1 0.5 2 8.7 0.5 2.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 VBB25768.1 - 0.11 11.8 0.2 12 5.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein STT3 PF02516.14 VBB25769.1 - 1.6e-129 433.0 43.9 5.5e-123 411.5 39.1 3.0 2 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 VBB25769.1 - 3.2e-06 27.4 9.0 3.2e-06 27.4 9.0 3.4 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Bac_export_2 PF01312.19 VBB25769.1 - 0.13 11.4 3.1 0.27 10.4 2.6 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Cation_ATPase_C PF00689.21 VBB25769.1 - 0.18 11.5 13.2 0.077 12.7 6.9 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus U-box PF04564.15 VBB25770.1 - 1.8e-30 104.9 0.0 5.6e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 U-box domain CHIP_TPR_N PF18391.1 VBB25770.1 - 1.2e-24 86.9 16.4 2.2e-24 86.0 16.4 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 VBB25770.1 - 1.4e-18 65.8 0.6 1.4e-07 31.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB25770.1 - 5.6e-17 60.4 0.4 0.00022 21.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB25770.1 - 8.5e-11 41.9 0.8 8e-10 38.8 0.5 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 VBB25770.1 - 1.4e-10 41.3 0.7 3.4e-06 27.3 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB25770.1 - 1.5e-08 34.1 0.1 0.0012 18.5 0.0 3.3 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 VBB25770.1 - 2.2e-08 33.6 0.0 0.02 15.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25770.1 - 2.3e-08 34.5 0.0 8.5e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB25770.1 - 2.7e-08 34.2 0.0 0.00014 22.3 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB25770.1 - 2e-07 30.5 0.3 0.0071 16.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB25770.1 - 1.6e-05 25.0 0.1 0.014 15.5 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB25770.1 - 5.5e-05 23.7 0.0 0.56 11.2 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 VBB25770.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF2785 PF10978.8 VBB25770.1 - 0.0015 18.3 1.6 0.0027 17.5 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2785) TPR_6 PF13174.6 VBB25770.1 - 0.0051 17.4 0.2 12 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex26 PF07163.12 VBB25770.1 - 0.0086 15.4 0.4 0.0086 15.4 0.4 1.6 1 1 1 2 2 2 1 Pex26 protein TPR_17 PF13431.6 VBB25770.1 - 0.015 15.6 0.8 9 6.9 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 VBB25770.1 - 0.072 13.0 0.4 8.7 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Arm PF00514.23 VBB25771.1 - 1.5e-72 237.6 25.4 2.1e-12 46.6 0.2 9.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 VBB25771.1 - 3.9e-27 93.6 4.6 6.1e-23 80.1 4.0 3.1 3 0 0 3 3 3 2 Atypical Arm repeat IBB PF01749.20 VBB25771.1 - 2.9e-21 75.7 3.4 7.3e-20 71.2 3.0 2.6 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 VBB25771.1 - 1.7e-19 69.9 8.0 1e-07 32.3 0.1 6.2 4 2 3 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 VBB25771.1 - 3.1e-16 59.5 1.2 0.019 15.3 0.1 5.9 2 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 VBB25771.1 - 5.1e-14 51.2 3.8 0.003 17.7 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.20 VBB25771.1 - 1.2e-06 27.4 0.0 1.3e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 VBB25771.1 - 9.7e-06 25.7 0.3 0.55 10.4 0.0 4.5 4 1 0 4 4 4 1 V-ATPase subunit H Arm_2 PF04826.13 VBB25771.1 - 0.00061 19.3 5.2 0.5 9.8 1.0 4.5 2 1 1 4 4 4 2 Armadillo-like Cnd1 PF12717.7 VBB25771.1 - 0.00067 19.7 0.3 1.1 9.2 0.1 4.1 2 2 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CTNNBL PF08216.11 VBB25771.1 - 0.015 15.4 0.6 28 4.9 0.0 4.7 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear MMS19_N PF14500.6 VBB25771.1 - 0.072 12.7 0.0 0.65 9.5 0.0 2.6 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DRIM PF07539.12 VBB25771.1 - 0.13 10.6 0.4 0.95 7.7 0.2 2.2 1 1 0 2 2 2 0 Down-regulated in metastasis Mo25 PF08569.11 VBB25771.1 - 0.15 11.4 0.0 4.4 6.6 0.0 2.2 2 1 0 2 2 2 0 Mo25-like DUF3048_C PF17479.2 VBB25771.1 - 0.17 12.3 0.6 0.45 10.9 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3048) C-terminal domain Proteasom_PSMB PF10508.9 VBB25771.1 - 0.24 9.8 1.4 0.7 8.3 0.3 2.2 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit PMI_typeI PF01238.21 VBB25772.1 - 3.7e-77 260.0 0.1 2.8e-61 207.8 0.0 2.3 2 1 1 3 3 3 2 Phosphomannose isomerase type I Cupin_2 PF07883.11 VBB25772.1 - 4.2e-06 26.4 0.0 0.0033 17.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 VBB25772.1 - 0.00048 20.1 0.0 2.4 8.1 0.0 3.3 3 0 0 3 3 3 2 AraC-like ligand binding domain AraC_N PF06719.13 VBB25772.1 - 0.052 13.2 0.1 0.36 10.5 0.0 2.3 2 1 0 2 2 2 0 AraC-type transcriptional regulator N-terminus DUF4795 PF16043.5 VBB25772.1 - 0.076 12.6 0.3 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) HEAT_2 PF13646.6 VBB25772.1 - 0.19 12.2 0.0 2.1 8.8 0.0 2.4 2 1 1 3 3 3 0 HEAT repeats OATP PF03137.20 VBB25773.1 - 1.3e-135 452.8 15.3 2e-135 452.2 15.3 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 VBB25773.1 - 1.7e-20 73.3 28.8 2.2e-20 72.9 14.4 3.0 2 2 0 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 VBB25774.1 - 3.3e-16 59.4 12.1 5.5e-15 55.4 12.1 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CPSase_sm_chain PF00988.22 VBB25776.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Metallophos PF00149.28 VBB25777.1 - 9.9e-36 124.2 0.0 1.4e-35 123.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB25777.1 - 1.8e-11 44.3 0.5 3.5e-11 43.4 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF2358 PF10184.9 VBB25779.1 - 2.4e-19 69.7 3.0 1.1e-14 54.7 0.2 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 VBB25779.1 - 1.7e-08 35.0 0.0 0.00036 21.1 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain zf-CCCH PF00642.24 VBB25783.1 - 3.9e-05 23.4 3.7 0.00053 19.8 0.5 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 VBB25783.1 - 0.0024 17.6 6.0 0.074 12.9 0.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger HrpB_C PF08482.10 VBB25783.1 - 0.0073 16.7 1.5 0.16 12.4 1.7 2.4 2 0 0 2 2 2 1 ATP-dependent helicase C-terminal zf-CCCH_2 PF14608.6 VBB25783.1 - 0.0081 16.6 5.8 0.39 11.3 0.4 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 VBB25783.1 - 0.14 12.3 0.8 0.31 11.3 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger containing family YueH PF14166.6 VBB25783.1 - 0.17 11.7 0.9 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 YueH-like protein Antifungal_prot PF11402.8 VBB25783.1 - 0.37 11.1 4.6 1.7 9.0 4.6 2.0 1 1 0 1 1 1 0 Antifungal protein zf_CCCH_4 PF18345.1 VBB25783.1 - 1.6 8.9 9.8 5.3 7.2 2.0 3.5 2 2 0 2 2 2 0 Zinc finger domain GPI2 PF06432.11 VBB25784.1 - 5.9e-41 140.8 17.2 7.1e-41 140.5 17.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase UNC-79 PF14776.6 VBB25784.1 - 0.04 12.7 2.3 0.054 12.2 2.3 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Beach PF02138.18 VBB25785.1 - 3e-108 361.4 0.6 1.7e-107 359.0 0.0 2.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 VBB25785.1 - 3.9e-12 46.1 0.2 1.1e-11 44.7 0.2 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH zf-C4 PF00105.18 VBB25786.1 - 2.9e-26 91.7 16.1 6.2e-26 90.7 16.1 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB25786.1 - 1.4e-25 90.1 5.6 3.3e-24 85.6 5.6 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PDZ PF00595.24 VBB25787.1 - 7.9e-63 208.8 8.8 6.9e-16 58.4 0.2 4.8 5 0 0 5 5 5 4 PDZ domain LRR_8 PF13855.6 VBB25787.1 - 3.2e-37 126.1 39.2 2.6e-09 36.7 0.3 6.7 2 1 7 9 9 9 9 Leucine rich repeat PDZ_6 PF17820.1 VBB25787.1 - 2.6e-34 116.9 5.2 1.1e-10 41.2 0.3 4.6 4 0 0 4 4 4 4 PDZ domain LRR_4 PF12799.7 VBB25787.1 - 3.5e-28 97.2 48.9 1.4e-05 25.3 3.8 9.0 2 2 6 10 10 10 10 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 VBB25787.1 - 5.5e-27 93.9 5.1 2e-06 28.0 0.1 5.1 5 0 0 5 5 5 4 PDZ domain LRR_1 PF00560.33 VBB25787.1 - 0.00019 21.5 43.2 0.92 10.3 0.1 12.5 11 3 1 12 12 12 3 Leucine Rich Repeat Tricorn_PDZ PF14685.6 VBB25787.1 - 0.00062 19.7 2.8 2.4 8.2 0.1 4.2 4 0 0 4 4 4 2 Tricorn protease PDZ domain LRR_6 PF13516.6 VBB25787.1 - 0.012 15.6 35.3 1.8 8.8 0.2 9.6 9 0 0 9 9 9 0 Leucine Rich repeat GRASP55_65 PF04495.14 VBB25787.1 - 0.078 13.3 0.0 0.29 11.4 0.0 2.0 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain C12orf66_like PF09404.10 VBB25788.1 - 5.2e-41 140.9 0.7 6.8e-41 140.5 0.7 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like MBOAT PF03062.19 VBB25789.1 - 5.8e-09 35.8 21.6 3.9e-08 33.0 21.6 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-Tim10_DDP PF02953.15 VBB25789.1 - 1.1 9.0 4.2 4.1 7.1 0.3 2.4 1 1 1 2 2 2 0 Tim10/DDP family zinc finger DGCR6 PF07324.11 VBB25790.1 - 9.5e-23 80.8 4.4 1.5e-13 50.8 0.2 2.7 1 1 1 2 2 2 2 DiGeorge syndrome critical region 6 (DGCR6) protein Ribosomal_L13 PF00572.18 VBB25790.1 - 3.3e-08 33.8 0.1 5.2e-06 26.7 0.0 3.3 2 1 0 2 2 2 1 Ribosomal protein L13 ELP6 PF09807.9 VBB25790.1 - 5e-06 26.1 0.0 8.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Elongation complex protein 6 LPD15 PF18828.1 VBB25791.1 - 0.089 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 DUF2922 PF11148.8 VBB25791.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) zf-C2H2 PF00096.26 VBB25792.1 - 3.8e-08 33.4 22.2 0.00076 19.8 1.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB25792.1 - 5.8e-08 32.9 19.6 0.012 16.4 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB25792.1 - 1.5e-05 25.2 19.7 0.032 14.7 1.3 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 VBB25792.1 - 6e-05 23.7 0.2 0.0011 19.7 0.0 2.7 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 VBB25792.1 - 0.0011 18.9 24.4 0.62 10.1 2.2 3.4 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB25792.1 - 0.068 13.5 2.3 0.09 13.1 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 VBB25792.1 - 0.16 12.2 10.5 4.9 7.4 0.3 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2HE PF16278.5 VBB25792.1 - 0.33 11.5 7.5 29 5.2 5.9 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_1 PF00130.22 VBB25792.1 - 0.34 10.8 4.6 5.6 6.9 1.3 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CpXC PF14353.6 VBB25792.1 - 0.75 9.9 4.2 24 5.0 0.0 2.9 2 1 1 3 3 3 0 CpXC protein PHD PF00628.29 VBB25792.1 - 2.3 8.2 7.2 3.6 7.6 1.8 2.9 3 0 0 3 3 3 0 PHD-finger Cnd1 PF12717.7 VBB25793.1 - 6.5e-46 156.3 12.4 1.2e-43 148.9 0.9 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Asparaginase_2 PF01112.18 VBB25793.1 - 3.9e-34 118.1 0.3 8.3e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 Asparaginase Cnd1_N PF12922.7 VBB25793.1 - 9.1e-11 41.9 2.5 4.3e-10 39.7 0.4 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd3 PF12719.7 VBB25793.1 - 4.2e-06 26.2 10.9 1.5e-05 24.4 8.2 3.1 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 VBB25793.1 - 3.1e-05 22.8 4.9 7e-05 21.6 0.4 2.9 2 1 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 VBB25793.1 - 0.00014 21.9 4.6 9.1 6.9 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 VBB25793.1 - 0.0027 18.0 0.3 1.4 9.4 0.0 4.6 4 1 1 5 5 5 1 HEAT repeats Sushi PF00084.20 VBB25794.1 - 1e-106 349.5 75.2 1.2e-10 41.8 0.3 16.3 15 1 1 16 16 16 15 Sushi repeat (SCR repeat) Ig_3 PF13927.6 VBB25794.1 - 0.025 15.2 0.1 0.62 10.7 0.0 3.6 3 0 0 3 3 3 0 Immunoglobulin domain V-set PF07686.17 VBB25794.1 - 0.07 13.3 0.0 4.7 7.4 0.0 3.3 2 0 0 2 2 2 0 Immunoglobulin V-set domain WAP PF00095.21 VBB25794.1 - 0.089 13.2 21.2 0.024 15.0 15.6 3.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' HRM PF02793.22 VBB25794.1 - 1.8 8.9 46.0 1.1 9.6 0.8 10.8 10 2 2 12 12 12 0 Hormone receptor domain IMPDH PF00478.25 VBB25795.1 - 5.8e-79 265.6 0.3 7.1e-79 265.3 0.3 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 VBB25795.1 - 6.8e-06 25.3 0.8 1.4e-05 24.4 0.8 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase dCache_3 PF14827.6 VBB25795.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Aldolase PF01081.19 VBB25795.1 - 0.17 11.3 0.4 3.8 6.9 0.0 2.3 1 1 1 2 2 2 0 KDPG and KHG aldolase HLH PF00010.26 VBB25796.1 - 2e-19 69.3 0.1 4.1e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 VBB25796.1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.25 VBB25798.1 - 5.2e-68 229.1 0.0 1.1e-67 228.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB25798.1 - 2.7e-48 163.3 0.0 4.6e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Glycos_transf_2 PF00535.26 VBB25798.1 - 1.6e-33 115.9 0.0 2.9e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB25798.1 - 3.1e-25 88.9 0.6 5.4e-25 88.1 0.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 VBB25798.1 - 5.8e-06 25.9 0.0 2.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 VBB25798.1 - 1.5e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Tubulin_3 PF14881.6 VBB25798.1 - 0.00084 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Glyco_tranf_2_2 PF10111.9 VBB25798.1 - 0.015 14.8 0.0 0.05 13.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase like family 2 LRR_8 PF13855.6 VBB25799.1 - 1.5e-53 178.4 72.3 1.4e-12 47.2 6.8 6.9 1 1 7 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 VBB25799.1 - 4.6e-21 74.6 45.8 5e-07 29.9 0.2 8.7 4 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB25799.1 - 2e-08 33.7 36.3 0.16 12.6 0.1 12.2 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 VBB25799.1 - 1.8e-07 30.9 11.8 7.7e-07 28.8 4.8 3.0 1 1 1 2 2 2 2 Leucine-rich repeat Amnionless PF14828.6 VBB25799.1 - 0.0032 16.3 2.1 0.33 9.7 0.9 2.1 2 0 0 2 2 2 2 Amnionless LRRNT PF01462.18 VBB25799.1 - 0.0044 16.6 1.3 0.0044 16.6 1.3 1.9 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 VBB25799.1 - 0.0092 16.0 36.4 3.2 8.0 0.1 9.9 11 0 0 11 11 11 4 Leucine Rich repeat DUF2027 PF09640.10 VBB25799.1 - 0.096 12.3 2.1 1.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2027) Patched PF02460.18 VBB25800.1 - 1.4e-138 463.4 30.3 4.9e-78 263.1 4.5 2.3 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 VBB25800.1 - 2.8e-32 111.7 10.3 2.8e-32 111.7 10.3 3.3 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 VBB25800.1 - 0.0016 16.2 9.8 0.0028 15.4 9.8 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Mo25 PF08569.11 VBB25800.1 - 0.062 12.7 0.1 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 Mo25-like Use1 PF09753.9 VBB25801.1 - 2.4e-51 174.8 7.1 3e-51 174.5 7.1 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 HSA PF07529.13 VBB25801.1 - 0.084 13.2 4.0 1.7 9.0 0.3 2.5 2 1 0 2 2 2 0 HSA Proteasome PF00227.26 VBB25802.1 - 1.2e-54 184.7 0.0 1.6e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 VBB25802.1 - 5e-14 51.6 0.1 8.7e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Trypsin PF00089.26 VBB25803.1 - 6.1e-29 101.4 0.0 8.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 VBB25803.1 - 0.00065 19.4 0.1 0.0028 17.3 0.1 1.9 1 1 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 VBB25803.1 - 0.0088 16.9 0.0 0.015 16.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain HUN PF08729.10 VBB25804.1 - 9.8e-19 67.1 0.7 3.8e-18 65.2 0.7 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.6 VBB25804.1 - 2.2e-07 30.8 0.7 1.4e-05 24.9 0.4 4.1 5 0 0 5 5 5 2 Ubinuclein conserved middle domain LRR_8 PF13855.6 VBB25805.1 - 1.6e-53 178.3 57.8 5.5e-15 54.9 0.9 8.0 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 VBB25805.1 - 6.7e-27 93.1 63.7 7.1e-06 26.3 0.4 7.9 4 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB25805.1 - 6.4e-17 61.7 11.7 1.5e-09 37.9 0.2 4.9 2 1 4 6 6 6 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB25805.1 - 1.6e-14 53.8 34.4 5.7e-07 29.2 7.7 5.6 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 VBB25805.1 - 7.6e-06 25.8 48.9 4.3 8.3 1.8 11.6 8 3 0 8 8 8 4 Leucine Rich Repeat HTH_19 PF12844.7 VBB25805.1 - 0.00067 19.6 1.0 0.39 10.8 0.1 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain SSP160 PF06933.11 VBB25805.1 - 8.8 4.4 18.1 13 3.8 18.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_C50 PF03568.17 VBB25806.1 - 6.5e-64 216.5 0.0 1.6e-53 182.3 0.0 2.3 1 1 1 2 2 2 2 Peptidase family C50 DUF1729 PF08354.10 VBB25806.1 - 0.13 11.1 0.8 0.34 9.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) PaRep2a PF07903.11 VBB25807.1 - 0.0064 16.3 0.2 0.0094 15.8 0.2 1.2 1 0 0 1 1 1 1 PaRep2a protein DDA1 PF10172.9 VBB25807.1 - 0.06 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase EF-hand_6 PF13405.6 VBB25808.1 - 1.6e-07 30.7 6.4 0.005 16.7 0.1 4.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 VBB25808.1 - 1.7e-07 30.3 3.4 0.053 13.1 0.1 4.4 4 2 1 5 5 5 2 EF hand EF-hand_7 PF13499.6 VBB25808.1 - 4e-07 30.4 0.2 0.0053 17.2 0.2 3.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 VBB25808.1 - 0.024 14.5 0.2 0.024 14.5 0.2 3.2 3 1 1 4 4 4 0 EF-hand domain pair VAPB_antitox PF02697.14 VBB25808.1 - 0.029 15.2 2.4 0.22 12.3 1.5 2.6 2 1 0 2 2 2 0 Putative antitoxin DUF1768 PF08719.11 VBB25810.1 - 7.6e-43 146.5 0.0 1.2e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Rox3 PF08633.10 VBB25810.1 - 0.32 11.2 12.1 0.79 10.0 12.1 1.7 1 0 0 1 1 1 0 Rox3 mediator complex subunit Glycos_transf_4 PF00953.21 VBB25811.1 - 8.6e-36 123.3 13.4 8.6e-36 123.3 13.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 TANGO2 PF05742.12 VBB25812.1 - 8.4e-46 157.1 0.1 5.4e-23 82.3 0.3 2.0 1 1 1 2 2 2 2 Transport and Golgi organisation 2 DUF3023 PF11224.8 VBB25812.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) TANGO2 PF05742.12 VBB25813.1 - 5.1e-54 184.0 0.0 5.8e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 STAR_dimer PF16544.5 VBB25813.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Sugar_tr PF00083.24 VBB25814.1 - 2.8e-21 75.9 15.4 1e-18 67.5 11.6 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 VBB25814.1 - 2.5e-20 72.7 13.6 1e-19 70.7 14.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 VBB25814.1 - 1e-08 34.9 9.0 8.3e-05 22.0 0.3 2.7 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4355 PF14265.6 VBB25815.1 - 2.2 8.5 15.8 0.36 11.1 11.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) TRAPP PF04051.16 VBB25817.1 - 8.8e-41 139.0 0.6 1.1e-40 138.8 0.6 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Rap_GAP PF02145.15 VBB25820.1 - 1e-66 224.0 0.1 1.7e-66 223.3 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP PDZ_6 PF17820.1 VBB25820.1 - 2.8e-06 27.1 0.0 5.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 PDZ domain APG6_N PF17675.1 VBB25820.1 - 0.27 11.7 10.2 0.6 10.6 10.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Swi5 PF07061.11 VBB25820.1 - 2.2 8.4 5.6 6.8 6.8 5.6 1.8 1 0 0 1 1 1 0 Swi5 HEAT_2 PF13646.6 VBB25821.1 - 1.8e-06 28.3 0.0 0.00019 21.7 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 VBB25821.1 - 0.055 13.8 0.2 5.2 7.6 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat DHO_dh PF01180.21 VBB25822.1 - 6.9e-50 169.9 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DAGK_cat PF00781.24 VBB25822.1 - 6.3e-22 77.5 0.1 1.1e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sin3a_C PF16879.5 VBB25824.1 - 6.9e-59 199.9 1.3 6.9e-59 199.9 1.3 3.1 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 VBB25824.1 - 1.6e-36 124.3 0.3 5e-36 122.7 0.3 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 VBB25824.1 - 7.1e-24 83.7 2.8 1.4e-12 47.6 0.0 4.2 3 0 0 3 3 3 3 Paired amphipathic helix repeat zf-C4 PF00105.18 VBB25826.1 - 2.1e-32 111.4 12.6 5.2e-32 110.1 12.6 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB25826.1 - 1.4e-10 41.1 0.6 2.5e-10 40.3 0.6 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MARVEL PF01284.23 VBB25828.1 - 0.001 19.1 8.8 0.0017 18.4 8.8 1.4 1 0 0 1 1 1 1 Membrane-associating domain MerR-DNA-bind PF09278.11 VBB25829.1 - 0.029 14.9 0.3 0.029 14.9 0.3 2.5 2 1 1 3 3 3 0 MerR, DNA binding YabA PF06156.13 VBB25829.1 - 0.78 10.4 19.4 2.3 8.9 2.6 3.8 2 2 1 3 3 3 0 Initiation control protein YabA DivIVA PF05103.13 VBB25829.1 - 3.3 7.8 14.6 0.19 11.8 6.9 2.4 2 1 0 2 2 2 0 DivIVA protein tRNA-synt_1 PF00133.22 VBB25830.1 - 2.5e-221 736.1 0.1 3.5e-221 735.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 VBB25830.1 - 1.1e-25 90.4 0.0 4.9e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 VBB25830.1 - 1.1e-10 40.9 0.2 0.0037 16.1 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 VBB25830.1 - 0.0049 16.3 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Cu2_monoox_C PF03712.15 VBB25830.1 - 0.1 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Tnp_22_dsRBD PF17490.2 VBB25830.1 - 0.1 12.6 0.1 0.43 10.6 0.0 2.1 1 1 1 2 2 2 0 L1 transposable element dsRBD-like domain WD40 PF00400.32 VBB25831.1 - 5.2e-25 87.2 5.6 0.00013 22.7 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB25831.1 - 6.9e-11 42.3 0.0 0.00094 19.4 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 VBB25831.1 - 0.00091 18.8 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain WD40_like PF17005.5 VBB25831.1 - 0.049 13.0 0.0 2.6 7.3 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain TPR_14 PF13428.6 VBB25833.1 - 5.9e-11 42.2 3.5 0.45 11.5 0.0 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat Suf PF05843.14 VBB25833.1 - 5.1e-06 26.7 9.4 0.0027 17.7 0.0 3.9 3 2 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 VBB25833.1 - 6.9e-05 22.1 3.3 0.00015 21.0 0.5 2.9 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 VBB25833.1 - 0.0004 19.7 1.0 1.8 7.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HAT PF02184.16 VBB25833.1 - 0.00069 19.5 12.2 0.58 10.2 0.1 5.1 4 0 0 4 4 4 2 HAT (Half-A-TPR) repeat Mad3_BUB1_I PF08311.12 VBB25833.1 - 0.0079 16.2 7.8 1.6 8.8 0.6 4.3 3 1 1 4 4 4 2 Mad3/BUB1 homology region 1 CDC37_M PF08565.11 VBB25833.1 - 0.022 14.7 0.4 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain TPR_8 PF13181.6 VBB25833.1 - 0.17 12.2 1.2 20 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3741 PF12552.8 VBB25833.1 - 0.17 11.8 1.6 1.3 9.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) TPR_6 PF13174.6 VBB25833.1 - 0.18 12.5 3.4 2.3 9.0 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25833.1 - 0.25 12.0 4.7 33 5.2 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB25833.1 - 0.35 11.4 2.1 21 5.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 VBB25835.1 - 9.4e-95 317.3 24.9 1.4e-89 300.3 16.2 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 VBB25835.1 - 1e-05 25.7 7.9 0.037 14.3 0.6 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB25835.1 - 0.00078 19.3 7.4 5.6 7.2 0.1 5.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB25835.1 - 0.018 15.2 7.4 0.24 11.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB25835.1 - 0.02 15.4 5.2 0.36 11.4 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 VBB25835.1 - 0.028 13.5 8.4 0.21 10.7 7.0 2.7 1 1 1 2 2 2 0 Spatacsin C-terminus DUF2076 PF09849.9 VBB25835.1 - 0.049 13.7 1.1 0.068 13.2 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ANAPC3 PF12895.7 VBB25835.1 - 0.087 13.1 5.7 0.39 11.0 0.5 3.1 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 VBB25835.1 - 0.39 10.8 5.6 3.3 7.9 0.4 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 VBB25835.1 - 0.62 10.0 11.2 26 4.9 0.2 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 VBB25835.1 - 0.95 9.2 6.1 2.9 7.6 1.0 3.3 2 1 2 4 4 4 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 VBB25835.1 - 1.6 8.9 4.1 16 5.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 VBB25835.1 - 7 7.8 10.0 7.8 7.6 0.1 4.8 4 1 2 6 6 5 0 Tetratricopeptide repeat Collagen PF01391.18 VBB25836.1 - 2e-10 40.2 40.2 8.4e-09 35.1 40.2 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) E2F_TDP PF02319.20 VBB25838.1 - 1.2e-23 83.0 0.2 3.5e-23 81.5 0.2 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 VBB25838.1 - 1.9e-22 79.4 0.0 4.8e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain NYD-SP12_N PF15015.6 VBB25838.1 - 0.0057 15.1 0.1 0.0083 14.5 0.1 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal Anophelin PF10731.9 VBB25838.1 - 0.21 11.5 2.9 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito WDCP PF15390.6 VBB25838.1 - 0.32 9.3 1.9 0.5 8.7 1.9 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Leo1 PF04004.13 VBB25839.1 - 5.2e-35 120.7 0.0 5.2e-35 120.7 0.0 2.9 3 0 0 3 3 3 1 Leo1-like protein STIL_N PF15253.6 VBB25839.1 - 3.3 6.5 7.9 0.094 11.6 1.0 1.8 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus MRP-S32 PF10210.9 VBB25840.1 - 2.8e-18 66.3 0.0 3.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 BPL_LplA_LipB PF03099.19 VBB25841.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF5392 PF17370.2 VBB25841.1 - 0.087 12.9 0.1 0.44 10.6 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5392) TTL PF03133.15 VBB25842.1 - 1.7e-40 139.0 0.6 2.5e-40 138.5 0.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Ant_C PF05586.11 VBB25842.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Anthrax receptor C-terminus region Pkinase PF00069.25 VBB25843.1 - 3e-26 92.4 0.0 4.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25843.1 - 2.5e-12 46.6 0.0 3.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25843.1 - 0.0019 17.0 0.1 0.0027 16.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sulfakinin PF08257.11 VBB25843.1 - 0.063 13.3 2.6 6.3 7.2 0.5 3.0 2 0 0 2 2 2 0 Sulfakinin family APH PF01636.23 VBB25843.1 - 0.15 12.0 0.1 1.1 9.1 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.27 VBB25846.1 - 2.8e-72 241.5 0.0 4.6e-35 120.7 0.0 2.8 2 0 0 2 2 2 2 RhoGAP domain C1_1 PF00130.22 VBB25846.1 - 1.2e-13 50.8 14.7 3.4e-07 30.0 0.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB25846.1 - 0.00054 20.2 12.7 0.025 14.9 1.0 2.6 2 0 0 2 2 2 2 C1 domain ERM PF00769.19 VBB25846.1 - 0.48 10.2 21.4 0.39 10.5 3.8 2.4 2 1 0 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.8 VBB25846.1 - 1.1 9.3 24.8 5.2 7.2 10.5 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 VBB25846.1 - 1.2 8.1 22.2 3.1 6.8 8.7 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Zf_RING PF16744.5 VBB25846.1 - 1.9 8.7 11.4 8.1 6.6 0.8 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger Rootletin PF15035.6 VBB25846.1 - 2.6 8.0 22.1 0.48 10.4 6.3 2.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.8 VBB25846.1 - 2.8 8.2 19.3 4.1 7.6 6.9 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PHD_2 PF13831.6 VBB25846.1 - 3.1 7.4 9.1 19 4.9 0.1 2.9 2 0 0 2 2 2 0 PHD-finger DASH_Dad3 PF08656.10 VBB25846.1 - 5 7.3 10.3 2.5 8.2 0.7 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad3 CENP-F_leu_zip PF10473.9 VBB25846.1 - 5.4 7.0 29.1 4.6 7.3 10.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHD PF00628.29 VBB25846.1 - 5.5 7.0 17.3 1.1 9.2 0.8 2.8 2 0 0 2 2 2 0 PHD-finger Laminin_II PF06009.12 VBB25846.1 - 5.6 7.0 12.2 14 5.7 4.3 3.0 2 1 0 2 2 2 0 Laminin Domain II zf-Mss51 PF13824.6 VBB25846.1 - 8.3 6.6 10.7 8.2 6.6 0.6 3.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TB2_DP1_HVA22 PF03134.19 VBB25847.1 - 5.3e-16 58.3 4.4 1e-15 57.4 4.4 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MannoseP_isomer PF01050.18 VBB25847.1 - 0.089 12.7 0.3 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase PCMT PF01135.19 VBB25848.1 - 1.5e-78 263.4 0.0 2e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 VBB25848.1 - 9.7e-08 31.9 0.1 2.4e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 VBB25848.1 - 2e-05 24.2 0.8 0.00015 21.3 0.1 2.0 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 VBB25848.1 - 2.7e-05 24.8 0.0 5.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 VBB25848.1 - 3.3e-05 23.9 1.3 7.3e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB25848.1 - 0.00049 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 VBB25848.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 VBB25848.1 - 0.0013 18.7 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB25848.1 - 0.0025 18.4 0.0 0.0064 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 VBB25848.1 - 0.0028 17.4 0.2 0.0047 16.6 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_23 PF13489.6 VBB25848.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 VBB25848.1 - 0.03 13.5 0.1 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase FtsJ PF01728.19 VBB25848.1 - 0.049 13.7 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 VBB25848.1 - 0.061 12.2 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DEAD PF00270.29 VBB25849.1 - 2e-43 148.2 0.0 4.5e-43 147.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB25849.1 - 2.5e-31 108.3 0.1 2.1e-29 102.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB25849.1 - 1.9e-05 24.8 0.0 5.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 VBB25849.1 - 0.056 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 VBB25850.1 - 1.1e-26 93.5 2.8 1.1e-26 93.5 2.8 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 VBB25850.1 - 3e-24 85.8 3.3 3.3e-24 85.6 0.2 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 VBB25850.1 - 5.7e-06 26.3 2.8 9.4e-06 25.6 0.2 2.6 2 0 0 2 2 2 1 Vps51/Vps67 DUF2451 PF10474.9 VBB25850.1 - 0.0027 17.5 5.3 0.0088 15.9 0.2 3.6 3 2 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Syntaxin-6_N PF09177.11 VBB25850.1 - 1.1 9.9 4.6 3.3 8.3 0.3 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Pkinase PF00069.25 VBB25851.1 - 3.8e-58 196.9 0.3 4.9e-58 196.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25851.1 - 7.3e-44 150.0 0.2 9.4e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25851.1 - 1.2e-05 24.3 0.1 0.00015 20.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 VBB25851.1 - 0.00015 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB25851.1 - 0.0062 15.5 1.0 0.0092 15.0 1.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 VBB25851.1 - 0.0086 15.4 0.1 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Motile_Sperm PF00635.26 VBB25852.1 - 6.3e-22 77.5 0.0 8e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain P19Arf_N PF07392.12 VBB25852.1 - 0.039 14.4 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Glycos_transf_2 PF00535.26 VBB25853.1 - 1.4e-15 57.5 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 VBB25853.1 - 3.8e-06 26.6 0.0 5.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 VBB25853.1 - 6.7e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fer2 PF00111.27 VBB25853.1 - 5.6e-05 23.0 0.2 9.7e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GFO_IDH_MocA PF01408.22 VBB25853.1 - 0.19 12.6 0.0 0.41 11.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PWI PF01480.17 VBB25854.1 - 1.6e-29 102.0 0.2 2.9e-29 101.2 0.2 1.4 1 0 0 1 1 1 1 PWI domain Epimerase PF01370.21 VBB25855.1 - 3e-48 164.4 0.0 4.8e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 VBB25855.1 - 4e-47 161.2 0.0 8.4e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase GTP_EFTU PF00009.27 VBB25855.1 - 1.2e-25 90.2 1.1 2.3e-25 89.3 1.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Polysacc_synt_2 PF02719.15 VBB25855.1 - 2.8e-15 56.2 0.0 2.1e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 VBB25855.1 - 1.4e-13 50.5 0.0 2.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 VBB25855.1 - 2.6e-10 39.9 0.0 5.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain MMR_HSR1 PF01926.23 VBB25855.1 - 3.8e-10 39.9 0.1 1.1e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase KR PF08659.10 VBB25855.1 - 2.8e-07 30.6 0.0 1.3e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 VBB25855.1 - 1e-06 28.2 0.0 5.4e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein SRPRB PF09439.10 VBB25855.1 - 1.6e-05 24.5 0.3 3e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RIBIOP_C PF04950.12 VBB25855.1 - 2.3e-05 24.0 0.4 4.6e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal GTP_EFTU_D2 PF03144.25 VBB25855.1 - 0.00016 22.0 0.2 0.016 15.6 0.1 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 VBB25855.1 - 0.00052 19.6 1.3 0.0042 16.6 0.3 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B adh_short PF00106.25 VBB25855.1 - 0.00071 19.1 0.1 0.0019 17.7 0.0 1.8 2 0 0 2 2 1 1 short chain dehydrogenase PduV-EutP PF10662.9 VBB25855.1 - 0.001 18.8 0.3 0.0079 16.0 0.3 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NAD_binding_10 PF13460.6 VBB25855.1 - 0.0037 17.2 0.0 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding cobW PF02492.19 VBB25855.1 - 0.038 13.6 2.1 0.04 13.5 0.2 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 VBB25855.1 - 0.038 13.9 1.6 0.11 12.4 0.5 2.2 1 1 1 2 2 2 0 RsgA GTPase NmrA PF05368.13 VBB25855.1 - 0.078 12.5 0.1 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family MMR_HSR1_Xtn PF16897.5 VBB25855.1 - 0.093 12.7 0.3 0.28 11.2 0.3 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain adh_short_C2 PF13561.6 VBB25855.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TraN PF06986.11 VBB25856.1 - 0.04 13.6 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation NDUF_B7 PF05676.13 VBB25857.1 - 2.1e-23 81.8 4.8 2.6e-23 81.5 4.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Reprolysin_5 PF13688.6 VBB25858.1 - 2.4e-29 102.9 0.4 9.7e-29 100.9 0.4 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 VBB25858.1 - 1.3e-28 100.3 0.3 2.5e-28 99.3 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 VBB25858.1 - 9.9e-20 71.3 0.1 1.8e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 VBB25858.1 - 3.2e-07 30.2 0.4 9.5e-07 28.7 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 VBB25858.1 - 7.1e-05 22.8 0.0 0.00023 21.1 0.0 1.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease MRP-S27 PF10037.9 VBB25859.1 - 2.8e-66 224.0 7.8 2.8e-66 224.0 7.8 1.7 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S27 BORCS8 PF10167.9 VBB25859.1 - 4.3e-25 87.8 0.2 4.3e-25 87.8 0.2 2.2 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 CtsR PF05848.11 VBB25859.1 - 0.058 13.3 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 CtsR N-terminal HTH domain RRP36 PF06102.12 VBB25859.1 - 0.39 10.7 7.5 0.76 9.7 7.5 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 TM2 PF05154.16 VBB25860.1 - 5.9e-14 52.1 9.2 1.1e-13 51.3 9.2 1.4 1 0 0 1 1 1 1 TM2 domain Pkinase PF00069.25 VBB25861.1 - 1.5e-52 178.6 0.0 1.8e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25861.1 - 6.7e-30 104.2 0.0 8.7e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25861.1 - 9.9e-06 24.6 0.0 1.9e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase PB1 PF00564.24 VBB25861.1 - 1.3e-05 25.0 0.0 3.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 VBB25861.1 - 0.0054 16.1 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pro_isomerase PF00160.21 VBB25862.1 - 1.6e-50 171.5 0.3 1.9e-50 171.2 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAW PF04721.17 VBB25863.1 - 2.5e-24 86.2 1.1 4.8e-24 85.2 1.1 1.5 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin PF00085.20 VBB25863.1 - 6.1e-24 84.0 0.0 1.7e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.19 VBB25863.1 - 2.2e-13 50.6 0.3 4.2e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 VBB25863.1 - 1.2e-07 31.5 0.9 2.4e-07 30.5 0.2 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Thioredoxin_8 PF13905.6 VBB25863.1 - 6.3e-05 23.2 0.1 0.00066 20.0 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 VBB25863.1 - 6.9e-05 22.8 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 VBB25863.1 - 0.00017 21.4 0.2 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 VBB25863.1 - 0.00057 20.3 0.1 0.0097 16.3 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.10 VBB25863.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 VBB25863.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Na_H_Exchanger PF00999.21 VBB25864.1 - 1.8e-41 142.2 30.3 2.4e-41 141.8 30.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Filament PF00038.21 VBB25865.1 - 8.7e-48 163.5 63.6 2.5e-47 162.0 63.6 1.7 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 VBB25865.1 - 3.7e-16 59.5 0.3 9.7e-16 58.1 0.1 1.7 2 0 0 2 2 2 1 Lamin Tail Domain DUF4407 PF14362.6 VBB25865.1 - 0.0042 16.5 33.0 0.046 13.1 13.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) FlxA PF14282.6 VBB25865.1 - 0.041 13.9 0.1 0.041 13.9 0.1 4.7 3 1 2 5 5 5 0 FlxA-like protein GbpA_2 PF18416.1 VBB25865.1 - 0.081 13.2 0.0 1.7 9.0 0.0 2.9 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 YvrJ PF12841.7 VBB25865.1 - 0.29 10.7 3.2 5.7 6.6 0.1 3.2 3 0 0 3 3 3 0 YvrJ protein family PulA_N1 PF17999.1 VBB25865.1 - 0.37 11.6 5.0 9.3 7.1 0.5 3.3 2 1 0 2 2 2 0 Pullulanase N1-terminal domain GAS PF13851.6 VBB25865.1 - 4.2 6.7 55.9 0.18 11.2 8.7 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FAM184 PF15665.5 VBB25865.1 - 7.3 6.3 47.8 0.99 9.1 22.7 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B 5_3_exonuc_N PF02739.16 VBB25865.1 - 7.7 6.4 7.8 0.63 9.9 0.7 2.5 2 1 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Adap_comp_sub PF00928.21 VBB25867.1 - 1.7e-88 296.4 0.1 3.4e-88 295.5 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 VBB25867.1 - 5.6e-05 23.1 3.8 0.0001 22.2 3.8 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain IF-2B PF01008.17 VBB25868.1 - 3.8e-30 105.1 3.1 1.1e-27 97.0 3.1 2.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family DNA_pol_phi PF04931.13 VBB25868.1 - 0.16 10.1 14.6 0.079 11.1 12.3 1.7 2 0 0 2 2 2 0 DNA polymerase phi BUD22 PF09073.10 VBB25868.1 - 0.61 9.4 7.4 1 8.7 7.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 VBB25868.1 - 1.3 7.2 7.0 2.6 6.2 6.8 1.5 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 VBB25868.1 - 1.4 8.3 12.1 2.2 7.6 12.1 1.2 1 0 0 1 1 1 0 SDA1 Med8 PF10232.9 VBB25868.1 - 5.4 6.5 6.4 1.1 8.8 0.2 2.6 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Nop14 PF04147.12 VBB25868.1 - 7.2 4.7 14.9 11 4.1 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family TUDOR PF00567.24 VBB25869.1 - 3.6e-18 65.8 0.0 2.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Tudor domain DUF3511 PF12023.8 VBB25869.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) eRF1_1 PF03463.15 VBB25870.1 - 1e-35 122.6 0.0 1.6e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 VBB25870.1 - 8.4e-29 100.6 0.2 1.8e-28 99.5 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 VBB25870.1 - 1.3e-20 74.0 0.1 1.1e-19 70.9 0.1 2.4 1 1 0 1 1 1 1 eRF1 domain 3 Cue1_U7BR PF18499.1 VBB25870.1 - 0.0052 16.8 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 1 Ubc7p-binding region of Cue1 bZIP_1 PF00170.21 VBB25871.1 - 1.7e-10 40.9 14.5 3.2e-10 40.0 14.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 VBB25871.1 - 1.7e-05 24.8 15.0 1.7e-05 24.8 15.0 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 VBB25871.1 - 0.00023 21.6 14.1 0.00049 20.6 14.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor UPF0449 PF15136.6 VBB25871.1 - 0.65 10.5 3.7 1.6 9.2 3.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 ZapB PF06005.12 VBB25871.1 - 0.78 10.2 13.4 0.051 14.0 4.8 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DnaJ PF00226.31 VBB25872.1 - 2.3e-28 98.1 1.8 5.7e-28 96.8 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain IMS_HHH PF11798.8 VBB25872.1 - 0.06 13.7 0.2 0.19 12.1 0.2 1.9 1 0 0 1 1 1 0 IMS family HHH motif FadA PF09403.10 VBB25872.1 - 2.7 8.5 9.3 0.41 11.2 4.1 2.2 2 1 0 2 2 2 0 Adhesion protein FadA Brix PF04427.18 VBB25873.1 - 6.7e-39 134.0 1.5 1.4e-38 132.9 1.5 1.6 1 0 0 1 1 1 1 Brix domain AP3D1 PF06375.11 VBB25873.1 - 0.85 9.9 9.5 0.089 13.0 4.7 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Phospho_p8 PF10195.9 VBB25874.1 - 3.8e-15 56.1 5.0 4.6e-15 55.9 5.0 1.1 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 PcfK PF14058.6 VBB25875.1 - 0.01 16.1 5.7 0.19 12.0 0.2 2.8 2 0 0 2 2 2 0 PcfK-like protein HTH_29 PF13551.6 VBB25875.1 - 0.49 10.5 1.8 0.7 9.9 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Pkinase PF00069.25 VBB25876.1 - 3.7e-17 62.6 0.1 7.1e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I PF08311.12 VBB25876.1 - 3.8e-07 30.1 1.1 7.9e-07 29.1 1.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.17 VBB25876.1 - 1.5e-06 27.7 0.0 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25876.1 - 0.021 13.6 0.1 0.044 12.6 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase TSP_1 PF00090.19 VBB25876.1 - 0.05 13.8 0.9 0.21 11.9 0.9 2.1 1 0 0 1 1 1 0 Thrombospondin type 1 domain DUF726 PF05277.12 VBB25877.1 - 2 7.3 9.7 3.2 6.6 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) La PF05383.17 VBB25879.1 - 1.5e-19 69.8 0.1 2.9e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 La domain SNF2_N PF00176.23 VBB25880.1 - 6.8e-16 57.9 0.0 1.7e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain HARP PF07443.13 VBB25880.1 - 9.1e-15 54.0 0.6 4e-14 52.0 0.1 2.3 1 1 1 2 2 2 1 HepA-related protein (HARP) Helicase_C PF00271.31 VBB25880.1 - 1.9e-10 41.1 0.1 7e-10 39.2 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.24 VBB25881.1 - 3.8e-103 345.8 30.3 1.6e-81 274.5 13.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 VBB25881.1 - 8.6e-26 90.7 27.0 4.9e-24 84.9 16.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 VBB25881.1 - 2.6e-07 29.4 2.6 2.6e-07 29.4 2.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 VBB25881.1 - 1.3e-06 27.5 0.0 0.036 12.9 4.9 2.4 1 1 1 2 2 2 2 MFS_1 like family PSI PF01437.25 VBB25881.1 - 0.52 10.9 9.6 1.9 9.1 9.4 2.1 1 1 1 2 2 2 0 Plexin repeat DUF389 PF04087.14 VBB25881.1 - 2.3 8.3 13.1 0.14 12.2 5.7 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF389) V-SNARE_C PF12352.8 VBB25882.1 - 2.9e-10 40.3 2.1 3.9e-10 39.9 0.2 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 VBB25882.1 - 0.038 14.4 0.1 0.084 13.3 0.1 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus HCR PF07111.12 VBB25882.1 - 0.04 12.0 0.3 0.046 11.8 0.3 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) CobN-Mg_chel PF02514.16 VBB25882.1 - 0.048 11.4 0.4 0.05 11.4 0.4 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase CorA PF01544.18 VBB25882.1 - 0.15 11.3 2.7 0.45 9.8 0.2 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2408 PF10303.9 VBB25882.1 - 0.23 12.0 3.4 2.2 8.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Asp_protease PF09668.10 VBB25883.1 - 6.6e-49 164.8 0.7 1.2e-48 163.9 0.7 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 VBB25883.1 - 6.7e-18 65.1 0.1 1.9e-17 63.6 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 VBB25883.1 - 2.5e-09 37.6 0.0 5.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 VBB25883.1 - 9.7e-08 31.9 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 VBB25883.1 - 5.1e-06 26.3 1.5 1.1e-05 25.3 1.5 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 VBB25883.1 - 0.00014 22.1 0.0 0.00032 20.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UPF0051 PF01458.17 VBB25883.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) UBA_4 PF14555.6 VBB25883.1 - 0.11 12.4 0.4 0.32 10.8 0.4 1.8 2 0 0 2 2 2 0 UBA-like domain bZIP_2 PF07716.15 VBB25884.1 - 8.9e-07 28.9 3.6 8.9e-07 28.9 3.6 2.5 2 0 0 2 2 2 1 Basic region leucine zipper PKcGMP_CC PF16808.5 VBB25884.1 - 0.00016 21.5 2.6 0.41 10.5 0.2 2.5 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase YabA PF06156.13 VBB25884.1 - 0.0014 19.2 3.6 0.0014 19.2 3.6 2.4 1 1 1 2 2 2 1 Initiation control protein YabA Yuri_gagarin PF15934.5 VBB25884.1 - 0.0036 17.2 5.4 0.0086 15.9 5.4 1.7 1 0 0 1 1 1 1 Yuri gagarin CC2-LZ PF16516.5 VBB25884.1 - 0.0061 16.9 8.3 0.021 15.2 7.5 2.2 2 0 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BLOC1_2 PF10046.9 VBB25884.1 - 0.034 14.5 4.0 0.8 10.0 1.2 2.8 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4883 PF16224.5 VBB25884.1 - 0.061 13.6 7.1 0.8 10.0 1.9 2.3 2 0 0 2 2 2 0 DOmain of unknown function (DUF4883) bZIP_1 PF00170.21 VBB25884.1 - 0.27 11.3 13.2 0.23 11.6 2.0 2.7 2 0 0 2 2 2 0 bZIP transcription factor DUF2808 PF10989.8 VBB25884.1 - 0.37 10.8 8.7 0.14 12.1 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2808) TSC22 PF01166.18 VBB25884.1 - 0.49 10.7 5.4 0.14 12.5 1.4 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF724 PF05266.14 VBB25884.1 - 1.2 9.0 11.4 1 9.2 9.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2205 PF10224.9 VBB25884.1 - 1.5 8.8 7.2 7 6.7 7.2 2.1 1 1 0 1 1 1 0 Short coiled-coil protein UPF0242 PF06785.11 VBB25884.1 - 4.6 7.3 11.9 4.7 7.3 10.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UDPGP PF01704.18 VBB25885.1 - 5.7e-155 516.0 0.8 7.6e-155 515.6 0.8 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase HA2 PF04408.23 VBB25885.1 - 4.7e-19 68.7 0.0 1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 VBB25885.1 - 4.5e-12 46.2 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 VBB25885.1 - 2e-09 37.8 0.1 3e-08 34.0 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB25885.1 - 0.00062 19.6 0.1 0.002 17.9 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 VBB25885.1 - 0.0012 19.2 0.1 0.0027 18.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 VBB25885.1 - 0.0012 19.1 0.1 0.0055 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 VBB25885.1 - 0.0037 17.8 0.9 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 VBB25885.1 - 0.011 15.4 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 VBB25885.1 - 0.029 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 VBB25885.1 - 0.16 12.5 0.0 0.57 10.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Smg4_UPF3 PF03467.15 VBB25886.1 - 4.7e-37 127.7 0.3 4.7e-37 127.7 0.3 3.3 1 1 1 2 2 2 1 Smg-4/UPF3 family Phage_antitermQ PF06530.12 VBB25886.1 - 6.5 6.7 7.0 14 5.7 0.3 3.2 4 0 0 4 4 4 0 Phage antitermination protein Q CTP_transf_like PF01467.26 VBB25887.1 - 2.5e-26 92.6 0.0 1.6e-25 90.0 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase-like Ank_2 PF12796.7 VBB25888.1 - 1.5e-102 336.4 15.3 3.4e-14 53.2 0.0 10.5 4 4 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB25888.1 - 8e-101 328.8 25.9 2.8e-12 46.6 0.0 14.3 6 4 8 14 14 14 14 Ankyrin repeats (many copies) Ank_4 PF13637.6 VBB25888.1 - 3.5e-93 304.9 30.1 3.2e-11 43.5 0.0 13.2 5 5 9 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 VBB25888.1 - 4.1e-87 283.1 28.7 2.2e-07 31.0 0.0 17.4 18 0 0 18 18 18 15 Ankyrin repeat Ank_3 PF13606.6 VBB25888.1 - 1.5e-80 255.4 27.8 2.6e-05 24.2 0.0 18.7 19 0 0 19 19 19 15 Ankyrin repeat PARP PF00644.20 VBB25888.1 - 1.3e-22 80.3 4.2 1.8e-20 73.4 4.2 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.30 VBB25888.1 - 1.6e-10 41.3 0.2 4.1e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB25888.1 - 3e-09 36.8 0.1 7.2e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras PF00071.22 VBB25889.1 - 9.5e-54 181.4 0.0 1.1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB25889.1 - 3.6e-23 82.1 0.0 4.9e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB25889.1 - 4.6e-09 36.0 0.0 9e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB25889.1 - 0.015 14.8 0.1 0.028 14.0 0.0 1.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 VBB25889.1 - 0.03 13.7 0.0 0.052 13.0 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 VBB25889.1 - 0.037 13.4 0.0 0.046 13.1 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_hydro_38N PF01074.22 VBB25890.1 - 1.1e-64 218.7 2.3 5.6e-43 147.4 1.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 VBB25890.1 - 4.3e-48 164.2 0.2 7.5e-48 163.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 VBB25890.1 - 2.3e-17 62.9 0.0 6e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 VBB25890.1 - 0.00014 21.9 0.5 0.0029 17.7 0.6 3.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain I-set PF07679.16 VBB25891.1 - 6.8e-127 413.9 38.4 5.8e-16 58.3 0.2 15.5 15 0 0 15 15 15 13 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB25891.1 - 1.2e-85 282.2 14.4 1.5e-13 51.2 0.1 14.4 14 0 0 14 14 13 11 Immunoglobulin domain fn3 PF00041.21 VBB25891.1 - 1.7e-77 255.9 3.1 2e-15 56.9 0.0 7.1 6 0 0 6 6 6 6 Fibronectin type III domain Ig_2 PF13895.6 VBB25891.1 - 2.8e-38 130.1 12.0 1.7e-09 37.8 0.0 12.7 14 0 0 14 14 14 5 Immunoglobulin domain ig PF00047.25 VBB25891.1 - 9.1e-32 109.1 16.7 2.1e-05 24.6 0.0 11.6 12 0 0 12 12 11 6 Immunoglobulin domain V-set PF07686.17 VBB25891.1 - 3.2e-15 56.2 30.9 0.76 10.0 0.2 15.5 14 4 0 14 14 14 6 Immunoglobulin V-set domain fn3_2 PF16893.5 VBB25891.1 - 9.5e-12 44.9 0.0 0.02 15.0 0.0 6.0 6 0 0 6 6 6 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB25891.1 - 2.2e-08 34.5 9.6 0.07 13.7 0.1 8.1 8 0 0 8 8 8 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 VBB25891.1 - 2.9e-08 33.7 12.8 0.068 13.2 0.0 8.1 8 0 0 8 8 8 3 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 VBB25891.1 - 2.1e-06 27.7 0.0 0.26 11.4 0.0 5.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 VBB25891.1 - 1.3e-05 25.0 1.7 0.031 14.1 0.0 5.2 6 0 0 6 6 6 1 Tissue factor Receptor_2B4 PF11465.8 VBB25891.1 - 3.3e-05 24.0 34.3 2.4 8.4 0.0 12.9 13 2 2 15 15 14 2 Natural killer cell receptor 2B4 DUF2369 PF10179.9 VBB25891.1 - 0.00017 21.9 1.5 3.8 8.0 0.0 5.2 4 0 0 4 4 3 1 Uncharacterised conserved protein (DUF2369) Ig_4 PF16680.5 VBB25891.1 - 0.0005 20.3 28.9 0.53 10.6 0.0 10.3 10 0 0 10 10 10 2 T-cell surface glycoprotein CD3 delta chain Y_Y_Y PF07495.13 VBB25891.1 - 0.0017 18.3 1.2 1.8 8.6 0.2 4.8 4 0 0 4 4 4 1 Y_Y_Y domain DUF2914 PF11141.8 VBB25891.1 - 0.0099 15.6 0.1 0.27 11.0 0.1 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2914) fn3_4 PF16794.5 VBB25891.1 - 0.013 15.4 1.4 65 3.5 0.1 5.5 6 0 0 6 6 5 0 Fibronectin-III type domain Herpes_gE PF02480.16 VBB25891.1 - 0.029 13.1 0.1 4.3 6.0 0.0 3.1 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ion_trans PF00520.31 VBB25892.1 - 6.1e-38 130.4 10.1 6.1e-38 130.4 10.1 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 VBB25892.1 - 3e-18 66.0 0.0 7.8e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 VBB25892.1 - 4.9e-14 52.1 7.9 1.4e-13 50.5 7.9 1.8 1 0 0 1 1 1 1 Ion channel DUF423 PF04241.15 VBB25892.1 - 0.032 14.4 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF423) BTB_3 PF16017.5 VBB25892.1 - 0.076 13.1 0.1 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain PKD_channel PF08016.12 VBB25892.1 - 1.8 7.2 11.4 0.088 11.5 4.3 2.2 2 1 0 2 2 2 0 Polycystin cation channel I-set PF07679.16 VBB25893.1 - 4.8e-234 757.3 0.2 3.4e-18 65.5 0.0 16.3 16 0 0 16 16 16 15 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB25893.1 - 2.2e-167 544.1 0.7 4.4e-13 49.6 0.0 15.6 15 0 0 15 15 15 14 Immunoglobulin domain Ig_2 PF13895.6 VBB25893.1 - 1.9e-87 287.7 9.8 1.5e-07 31.6 0.0 14.7 14 0 0 14 14 14 14 Immunoglobulin domain ig PF00047.25 VBB25893.1 - 5.1e-79 260.5 5.1 3.6e-07 30.3 0.0 14.7 15 0 0 15 15 15 11 Immunoglobulin domain Pkinase PF00069.25 VBB25893.1 - 2.4e-66 223.8 0.2 4e-66 223.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25893.1 - 5.3e-34 117.7 0.2 5.3e-34 117.7 0.2 1.9 3 0 0 3 3 2 1 Protein tyrosine kinase V-set PF07686.17 VBB25893.1 - 1.1e-32 112.4 23.7 0.016 15.4 0.0 19.1 14 6 0 14 14 14 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB25893.1 - 8.7e-23 80.2 9.3 0.091 12.8 0.0 14.3 16 0 0 16 16 15 4 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 VBB25893.1 - 4.3e-17 62.2 0.6 5.9e-07 29.7 0.1 3.0 2 0 0 2 2 2 2 Fibronectin type III domain Ig_5 PF16681.5 VBB25893.1 - 2.5e-10 40.6 12.5 0.66 10.4 0.0 11.6 12 1 0 12 12 12 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 VBB25893.1 - 2.9e-09 37.1 10.2 7.1 6.9 0.0 10.7 13 0 0 13 13 11 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 VBB25893.1 - 3.7e-08 32.8 7.3 0.0069 15.9 0.0 7.8 9 0 0 9 9 7 1 Immunoglobulin domain Ig_4 PF16680.5 VBB25893.1 - 4e-08 33.4 15.0 3.7 7.9 0.1 12.4 14 1 0 14 14 13 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 VBB25893.1 - 7.3e-08 32.4 12.9 7.8 6.6 0.0 10.4 12 0 0 12 12 10 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 VBB25893.1 - 1.2e-07 32.0 11.7 7.3 7.0 0.0 10.7 12 1 1 13 13 10 1 Immunoglobulin C1-set domain BiPBP_C PF06832.12 VBB25893.1 - 1.3e-06 28.3 0.0 2.6 8.1 0.0 7.9 10 0 0 10 10 9 1 Penicillin-Binding Protein C-terminus Family Pur_ac_phosph_N PF16656.5 VBB25893.1 - 3.4e-05 24.3 2.9 0.18 12.4 0.0 3.7 3 0 0 3 3 2 2 Purple acid Phosphatase, N-terminal domain Kdo PF06293.14 VBB25893.1 - 7.4e-05 22.2 0.7 0.00016 21.1 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB25893.1 - 0.00015 21.2 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tissue_fac PF01108.17 VBB25893.1 - 0.00059 19.7 1.7 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 Tissue factor PhoD_N PF16655.5 VBB25893.1 - 0.0009 19.7 0.0 2.1 8.9 0.0 3.4 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain SusE PF14292.6 VBB25893.1 - 0.029 14.6 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 1 0 SusE outer membrane protein Interfer-bind PF09294.10 VBB25893.1 - 0.12 12.7 2.8 1.5 9.2 0.0 3.9 4 1 1 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.11 VBB25893.1 - 6.5 6.8 12.0 7.2 6.6 0.0 6.5 9 0 0 9 9 8 0 CD47 immunoglobulin-like domain PDZ_2 PF13180.6 VBB25894.1 - 3.7e-13 49.6 0.5 3.8e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB25894.1 - 1.4e-11 44.1 0.9 5.4e-06 26.2 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB25894.1 - 1.4e-10 41.3 0.3 0.00062 20.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 VBB25894.1 - 0.0007 20.0 0.0 0.18 12.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 VBB25894.1 - 0.0011 18.9 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain TUDOR PF00567.24 VBB25895.1 - 6e-10 39.2 0.3 9.5e-07 28.9 0.0 2.8 2 1 0 2 2 2 2 Tudor domain ATPase PF06745.13 VBB25896.1 - 3.3e-05 23.3 0.7 0.66 9.3 0.1 3.2 1 1 2 3 3 3 3 KaiC DUF1758 PF05585.12 VBB25896.1 - 6.8e-05 22.7 0.0 3.1 7.5 0.0 3.3 1 1 4 5 5 5 5 Putative peptidase (DUF1758) DUF3216 PF11505.8 VBB25896.1 - 0.002 18.3 1.7 41 4.5 0.0 4.7 1 1 3 4 4 4 1 Protein of unknown function (DUF3216) Styelin PF17562.2 VBB25896.1 - 3 8.3 10.5 29 5.1 0.0 3.9 2 1 5 7 7 7 0 Styelin WD40 PF00400.32 VBB25897.1 - 4.3e-16 59.0 5.6 5.6e-05 23.8 0.1 5.7 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB25897.1 - 6.5e-05 23.2 0.0 0.36 11.2 0.0 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB25897.1 - 0.0043 16.4 0.0 1 8.7 0.0 2.3 1 1 0 2 2 2 2 WD40-like domain Cystatin PF00031.21 VBB25898.1 - 3e-08 33.8 2.1 4.7e-08 33.2 2.1 1.4 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 VBB25898.1 - 0.0086 16.4 0.3 0.012 16.0 0.3 1.3 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Imm30 PF15565.6 VBB25898.1 - 0.024 14.7 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 30 DUF4302 PF14135.6 VBB25898.1 - 0.073 13.0 0.4 0.091 12.7 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) DUF4614 PF15391.6 VBB25899.1 - 0.028 14.4 18.6 0.06 13.3 18.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 VBB25899.1 - 0.028 13.3 12.9 0.028 13.3 12.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 VBB25899.1 - 0.031 12.9 13.5 0.03 12.9 13.5 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 VBB25899.1 - 0.054 11.3 13.4 0.056 11.2 13.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Secretin_N_2 PF07655.13 VBB25899.1 - 0.075 13.6 23.4 0.23 12.0 23.4 2.0 1 0 0 1 1 1 0 Secretin N-terminal domain SOBP PF15279.6 VBB25899.1 - 0.53 10.8 7.0 0.58 10.7 7.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CDK2AP PF09806.9 VBB25899.1 - 0.84 9.7 12.0 1.4 8.9 12.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Presenilin PF01080.17 VBB25899.1 - 0.91 8.2 6.3 1.3 7.8 6.3 1.3 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.10 VBB25899.1 - 1 9.0 20.4 1.4 8.5 20.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 RSB_motif PF16294.5 VBB25900.1 - 0.0031 17.7 4.6 0.0038 17.5 4.6 1.1 1 0 0 1 1 1 1 RNSP1-SAP18 binding (RSB) motif MFS_1 PF07690.16 VBB25901.1 - 8e-42 143.4 43.2 1.2e-28 100.0 16.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 VBB25901.1 - 7.8e-06 25.0 22.9 0.011 14.6 6.3 4.1 1 1 1 2 2 2 2 MFS_1 like family ATG22 PF11700.8 VBB25901.1 - 0.001 17.8 9.4 0.001 17.8 9.4 2.1 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like CbtA PF09490.10 VBB25901.1 - 1.8 8.3 10.4 2.4 7.9 3.4 2.8 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Pkinase_Tyr PF07714.17 VBB25903.1 - 4.5e-97 324.4 0.0 1.8e-96 322.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 VBB25903.1 - 2.3e-47 161.6 0.0 5e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 VBB25903.1 - 9.4e-24 83.3 1.4 2.3e-23 82.1 1.4 1.7 1 0 0 1 1 1 1 SH2 domain F_actin_bind PF08919.10 VBB25903.1 - 3.9e-18 65.5 3.5 6.6e-18 64.8 1.2 2.6 2 0 0 2 2 2 1 F-actin binding SH3_1 PF00018.28 VBB25903.1 - 1.1e-10 41.0 0.0 3.5e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB25903.1 - 7.3e-10 38.5 0.0 3.7e-09 36.3 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 VBB25903.1 - 5.8e-07 29.1 0.0 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 VBB25903.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase PF00069.25 VBB25904.1 - 2.9e-39 135.0 0.3 1e-19 71.0 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25904.1 - 4.1e-21 75.4 0.0 5.1e-10 39.1 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 VBB25904.1 - 1.3e-16 60.9 0.0 3.8e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 VBB25904.1 - 5.2e-08 32.5 0.0 3.3e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Vasculin PF15337.6 VBB25904.1 - 0.016 16.1 0.0 0.083 13.7 0.0 2.2 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 DUF3678 PF12435.8 VBB25904.1 - 0.042 13.2 0.2 0.61 9.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Phage_G PF02306.15 VBB25905.1 - 0.25 11.1 3.5 0.82 9.4 0.6 2.2 1 1 0 2 2 2 0 Major spike protein (G protein) TSC22 PF01166.18 VBB25906.1 - 9.9e-24 83.4 2.2 1.7e-23 82.7 1.7 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family SOGA PF11365.8 VBB25906.1 - 0.011 16.9 0.4 0.024 15.7 0.4 1.7 1 0 0 1 1 1 0 Protein SOGA M PF02370.16 VBB25906.1 - 1.1 10.1 5.3 0.36 11.5 0.9 2.6 2 0 0 2 2 2 0 M protein repeat Fam20C PF06702.12 VBB25907.1 - 2.1e-83 279.5 0.4 2.1e-83 279.5 0.4 1.7 2 0 0 2 2 2 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 VBB25907.1 - 0.00035 19.5 0.0 0.00074 18.5 0.0 1.4 1 1 0 1 1 1 1 FAM198 protein DUF4047 PF13256.6 VBB25907.1 - 0.077 13.2 0.1 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) EF_assoc_2 PF08356.12 VBB25908.1 - 7.2e-30 102.8 0.0 2.3e-29 101.2 0.0 1.9 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 VBB25908.1 - 2e-24 86.0 0.1 3.8e-17 62.4 0.0 2.9 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 VBB25908.1 - 1.5e-22 79.0 0.5 4.2e-22 77.5 0.3 1.8 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 VBB25908.1 - 8.8e-14 51.8 0.0 2.1e-09 37.6 0.0 3.0 3 1 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 VBB25908.1 - 5.5e-09 35.2 1.1 0.00084 19.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 VBB25908.1 - 4.2e-08 32.2 1.3 0.0018 17.7 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 VBB25908.1 - 1.3e-07 31.9 0.1 3.5e-06 27.4 0.3 2.9 2 1 0 2 2 2 1 EF-hand domain pair ATP_bind_1 PF03029.17 VBB25908.1 - 1.4e-05 25.1 1.3 1.5 8.6 0.0 4.0 3 1 0 4 4 4 2 Conserved hypothetical ATP binding protein AAA PF00004.29 VBB25908.1 - 3.9e-05 24.1 0.4 0.069 13.6 0.0 3.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 VBB25908.1 - 5.1e-05 22.8 0.1 0.00035 20.1 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 VBB25908.1 - 5.6e-05 23.6 0.0 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 VBB25908.1 - 0.00012 22.4 0.0 0.31 11.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 VBB25908.1 - 0.00014 21.6 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 VBB25908.1 - 0.00019 21.4 0.0 0.009 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 VBB25908.1 - 0.00024 21.0 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.9 VBB25908.1 - 0.00028 20.6 2.2 0.83 9.4 0.2 3.7 2 2 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 VBB25908.1 - 0.00049 19.6 0.0 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_8 PF13833.6 VBB25908.1 - 0.00089 19.1 0.2 3.2 7.7 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair RsgA_GTPase PF03193.16 VBB25908.1 - 0.00093 19.1 5.3 0.69 9.8 0.0 4.9 4 1 1 6 6 5 1 RsgA GTPase MMR_HSR1 PF01926.23 VBB25908.1 - 0.00098 19.2 0.2 0.073 13.2 0.0 3.2 2 2 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 VBB25908.1 - 0.0016 17.8 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 VBB25908.1 - 0.0016 19.0 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 VBB25908.1 - 0.0016 18.0 0.0 0.34 10.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Pox_A32 PF04665.12 VBB25908.1 - 0.0021 17.5 0.1 2.5 7.5 0.0 2.9 3 1 0 3 3 2 2 Poxvirus A32 protein SPARC_Ca_bdg PF10591.9 VBB25908.1 - 0.0039 17.5 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_33 PF13671.6 VBB25908.1 - 0.0062 16.7 0.1 4.6 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 VBB25908.1 - 0.0063 16.5 0.0 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 VBB25908.1 - 0.014 15.4 0.0 0.49 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 VBB25908.1 - 0.015 15.7 0.0 4.8 7.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase EF-hand_5 PF13202.6 VBB25908.1 - 0.017 14.6 7.2 0.029 13.9 0.0 2.8 3 0 0 3 3 2 0 EF hand EF-hand_10 PF14788.6 VBB25908.1 - 0.019 14.8 1.3 0.73 9.7 0.2 2.5 2 0 0 2 2 2 0 EF hand MCM PF00493.23 VBB25908.1 - 0.034 13.2 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_25 PF13481.6 VBB25908.1 - 0.047 13.2 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 VBB25908.1 - 0.066 13.0 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 VBB25908.1 - 0.068 13.4 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 VBB25908.1 - 0.12 12.1 0.0 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 VBB25908.1 - 0.16 11.3 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 VBB25908.1 - 0.16 12.5 0.0 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 VBB25908.1 - 0.18 12.1 0.0 5.3 7.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Alpha_kinase PF02816.18 VBB25909.1 - 8.2e-61 205.3 0.3 1.5e-60 204.5 0.3 1.5 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 VBB25909.1 - 0.047 14.4 8.1 2.3 9.0 0.3 4.5 5 0 0 5 5 5 0 Sel1 repeat I-set PF07679.16 VBB25911.1 - 0.00022 21.2 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB25911.1 - 0.023 15.3 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 VBB25911.1 - 0.027 14.8 0.0 0.1 12.9 0.0 2.0 1 1 1 2 2 2 0 Immunoglobulin domain Mtc PF03820.17 VBB25912.1 - 1.4e-131 438.2 0.3 1.6e-131 438.0 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RA PF00788.23 VBB25913.1 - 2.1e-05 25.1 0.0 4.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain ADIP PF11559.8 VBB25913.1 - 0.19 11.8 12.1 0.082 13.0 2.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 VBB25913.1 - 0.52 10.8 11.3 1.3 9.6 11.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region AAA_23 PF13476.6 VBB25913.1 - 1 9.8 6.3 1.5 9.3 6.3 1.3 1 0 0 1 1 1 0 AAA domain CorA PF01544.18 VBB25913.1 - 2.1 7.6 7.6 7.2 5.8 7.6 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PCRF PF03462.18 VBB25913.1 - 8.7 6.2 9.8 1.1 9.0 3.8 2.0 1 1 1 2 2 2 0 PCRF domain DM13 PF10517.9 VBB25917.1 - 6e-07 30.0 3.4 2.3e-06 28.2 0.0 3.3 3 1 0 3 3 3 1 Electron transfer DM13 Troponin PF00992.20 VBB25918.1 - 2.5e-42 144.4 16.0 2.5e-42 144.4 16.0 3.0 3 1 0 3 3 3 1 Troponin Arc_PepC_II PF06847.11 VBB25918.1 - 4.9 7.8 7.7 0.89 10.1 0.2 2.8 2 2 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Syntaxin PF00804.25 VBB25919.1 - 3.4e-26 92.2 5.4 3.4e-26 92.2 5.4 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 VBB25919.1 - 5.7e-08 32.6 2.0 1.6e-07 31.2 2.0 1.8 1 0 0 1 1 1 1 SNARE domain SKA1 PF07160.12 VBB25919.1 - 0.017 14.9 2.3 0.017 14.9 2.3 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Baculo_PEP_C PF04513.12 VBB25919.1 - 0.024 14.7 11.9 2.1 8.4 0.2 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.6 VBB25919.1 - 0.3 11.5 5.2 0.31 11.5 0.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) NPV_P10 PF05531.12 VBB25919.1 - 1 9.9 7.0 9.4 6.8 0.3 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein WD-3 PF09765.9 VBB25919.1 - 1.2 8.4 8.6 0.58 9.4 2.0 2.6 1 1 2 3 3 3 0 WD-repeat region DUF4988 PF16378.5 VBB25919.1 - 1.5 8.5 6.7 0.48 10.1 1.0 2.5 2 1 1 3 3 3 0 Domain of unknown function Phg_2220_C PF09524.10 VBB25919.1 - 1.8 8.7 6.1 1.1 9.4 0.6 3.0 3 1 1 4 4 4 0 Conserved phage C-terminus (Phg_2220_C) Snapin_Pallidin PF14712.6 VBB25919.1 - 3.8 8.0 11.5 0.52 10.8 1.8 3.2 3 0 0 3 3 3 0 Snapin/Pallidin PAS_11 PF14598.6 VBB25920.1 - 2.6e-23 82.3 0.0 4.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 VBB25920.1 - 6e-06 26.5 0.4 6.3e-05 23.2 0.1 2.3 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 VBB25920.1 - 1.6e-05 24.9 0.2 0.00059 19.8 0.0 2.7 3 0 0 3 3 3 1 PAS fold SMC_N PF02463.19 VBB25922.1 - 1.1e-59 201.5 19.3 3.5e-59 199.9 19.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 VBB25922.1 - 1.9e-20 73.3 0.5 6.5e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 VBB25922.1 - 1.2e-12 48.2 3.3 7.6e-06 26.0 0.0 3.6 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 VBB25922.1 - 7.9e-09 35.7 19.1 7.9e-09 35.7 19.1 4.7 2 2 3 5 5 5 1 AAA ATPase domain AAA_29 PF13555.6 VBB25922.1 - 9.7e-08 31.6 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 VBB25922.1 - 0.007 16.6 0.0 0.036 14.3 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 VBB25922.1 - 2.8 8.4 118.1 0.0064 17.0 46.0 6.8 3 2 1 4 4 4 0 AAA domain tRNA-synt_1c PF00749.21 VBB25923.1 - 6.2e-110 367.0 0.2 1.3e-109 365.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 VBB25923.1 - 8.7e-42 142.9 1.1 1.6e-41 142.0 1.1 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 VBB25923.1 - 2.8e-38 131.5 0.1 6.4e-38 130.3 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 VBB25923.1 - 2.8e-24 85.9 3.5 5.9e-24 84.8 3.5 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF3504 PF12012.8 VBB25923.1 - 0.024 14.5 0.3 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) DUF155 PF02582.14 VBB25924.1 - 9.3e-36 123.6 0.1 1.3e-35 123.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 E1_dh PF00676.20 VBB25925.1 - 3.9e-97 324.8 0.4 4.8e-97 324.5 0.4 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 VBB25925.1 - 4.6e-05 22.5 0.1 9.2e-05 21.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 VBB25925.1 - 9.3e-05 22.3 0.5 0.00041 20.1 0.5 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 VBB25925.1 - 0.00022 20.5 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase IMS PF00817.20 VBB25927.1 - 1.9e-37 128.6 0.2 5.2e-37 127.1 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 VBB25927.1 - 5.6e-13 49.6 0.0 1.6e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 VBB25927.1 - 6.4e-09 36.1 0.0 8.1e-08 32.6 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 VBB25927.1 - 1.6e-06 28.4 0.1 5.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 VBB25927.1 - 4.6e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 VBB25927.1 - 0.00077 19.4 0.1 0.0023 17.8 0.1 1.9 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.11 VBB25927.1 - 0.17 12.2 0.3 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) AAA_34 PF13872.6 VBB25929.1 - 9.1e-135 448.4 0.0 1.4e-134 447.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 VBB25929.1 - 6.3e-117 390.1 0.0 1.2e-116 389.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 VBB25929.1 - 0.00011 22.3 0.0 0.00057 19.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RRN3 PF05327.11 VBB25929.1 - 0.047 12.2 5.7 0.067 11.7 4.7 1.6 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UAA PF08449.11 VBB25930.1 - 1.2e-35 123.2 2.3 1.6e-35 122.8 2.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 VBB25930.1 - 0.00026 21.2 0.1 0.00026 21.2 0.1 2.2 3 1 0 3 3 3 1 EamA-like transporter family CRT-like PF08627.10 VBB25930.1 - 0.0087 15.0 0.2 0.016 14.2 0.2 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like HAT PF02184.16 VBB25931.1 - 3.9e-25 87.5 57.4 4.2e-16 58.6 2.6 13.0 14 1 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 VBB25931.1 - 1.6e-12 47.1 22.3 2.8 9.0 0.0 10.6 4 3 7 11 11 11 3 Tetratricopeptide repeat Suf PF05843.14 VBB25931.1 - 3.8e-09 37.0 27.8 0.028 14.4 1.7 7.3 1 1 3 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 VBB25931.1 - 1.6e-08 34.9 0.7 0.37 11.3 0.0 5.7 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB25931.1 - 8.6e-07 28.9 1.4 0.0014 18.9 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB25931.1 - 1.2e-06 29.0 6.1 7.1 7.4 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 VBB25931.1 - 1.3e-05 25.2 23.5 0.00059 19.8 5.2 5.8 4 2 0 4 4 4 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 VBB25931.1 - 0.00016 21.5 9.6 6.7 7.1 0.3 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB25931.1 - 0.005 17.0 4.2 1.3e+02 3.2 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 VBB25931.1 - 0.017 15.1 1.2 0.017 15.1 1.2 5.1 4 1 0 5 5 5 0 U3 small nucleolar RNA-associated protein 6 ECSIT PF06239.11 VBB25931.1 - 0.036 13.2 0.6 0.099 11.8 0.6 1.7 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.6 VBB25931.1 - 0.05 13.9 7.5 11 6.3 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 VBB25931.1 - 0.083 12.3 3.1 2.5 7.4 0.0 3.4 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 VBB25931.1 - 0.28 11.4 7.0 21 5.3 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Apt1 PF10351.9 VBB25931.1 - 0.88 8.4 10.7 1.4 7.7 10.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Packaging_FI PF14000.6 VBB25931.1 - 8.9 6.8 8.9 12 6.3 8.1 1.7 2 0 0 2 2 2 0 DNA packaging protein FI Piwi PF02171.17 VBB25932.1 - 3.8e-54 184.0 0.0 6.4e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 VBB25932.1 - 0.00035 21.2 0.0 0.00085 20.0 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 VBB25932.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 0 Argonaute linker 2 domain CBFD_NFYB_HMF PF00808.23 VBB25933.1 - 1.3e-14 54.2 0.2 1.9e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB25933.1 - 1.3e-07 32.0 3.7 1.5e-06 28.6 0.2 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1876 PF08962.11 VBB25933.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) TetR_C_27 PF17935.1 VBB25933.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Prenyltrans PF00432.21 VBB25934.1 - 2.6e-44 148.6 13.5 8.9e-10 38.1 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 VBB25934.1 - 1.4e-05 24.4 0.0 0.066 12.3 0.0 3.2 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 VBB25934.1 - 0.00099 18.3 0.0 2.4 7.2 0.0 3.3 3 1 2 5 5 5 2 Squalene-hopene cyclase N-terminal domain CBF PF03914.17 VBB25935.1 - 1.2e-37 129.5 1.6 1.2e-37 129.5 1.6 2.7 3 1 0 3 3 3 1 CBF/Mak21 family CRR7 PF12095.8 VBB25935.1 - 0.012 16.0 0.5 0.048 14.1 0.5 2.0 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 Ribonuclease_T2 PF00445.18 VBB25936.1 - 8.1e-49 166.3 4.1 1e-48 166.0 4.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family VASP_tetra PF08776.11 VBB25937.1 - 4.7e-11 42.1 3.0 9.4e-11 41.1 3.0 1.5 1 0 0 1 1 1 1 VASP tetramerisation domain TubC_N PF18563.1 VBB25937.1 - 0.36 10.8 2.0 0.91 9.6 0.3 2.5 2 0 0 2 2 2 0 TubC N-terminal docking domain WH1 PF00568.23 VBB25938.1 - 1.1e-20 73.6 0.1 1.5e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 WH1 domain Rhomboid PF01694.22 VBB25939.1 - 1.9e-28 99.4 8.0 4e-28 98.3 8.0 1.6 1 0 0 1 1 1 1 Rhomboid family Citrus_P18 PF05520.11 VBB25939.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein TauE PF01925.19 VBB25939.1 - 0.65 9.6 11.1 3 7.4 10.8 2.0 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE MerC PF03203.14 VBB25939.1 - 2.1 8.8 8.4 1.1 9.7 3.7 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein PDZ_6 PF17820.1 VBB25941.1 - 1.2e-15 57.1 0.0 7.1e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB25941.1 - 1.3e-15 57.5 1.8 1.2e-09 38.3 0.7 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB25941.1 - 1.4e-09 38.1 0.0 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain KH_8 PF17903.1 VBB25943.1 - 3.8e-33 113.4 0.1 8.6e-33 112.3 0.1 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 VBB25943.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 VBB25943.1 - 0.029 14.2 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 KH domain RRM_1 PF00076.22 VBB25944.1 - 1.4e-07 31.2 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_primase_lrg PF04104.14 VBB25945.1 - 6.1e-81 271.7 0.1 6.1e-81 271.7 0.1 2.7 2 1 1 3 3 3 1 Eukaryotic and archaeal DNA primase, large subunit PWI PF01480.17 VBB25945.1 - 5.4e-15 55.5 0.5 5.4e-15 55.5 0.5 2.1 2 0 0 2 2 2 1 PWI domain AAA PF00004.29 VBB25946.1 - 1.1e-36 126.2 0.0 2.1e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 VBB25946.1 - 1.3e-06 28.4 0.0 1e-05 25.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB25946.1 - 9.9e-06 26.0 0.3 0.00094 19.6 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 VBB25946.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB25946.1 - 8.7e-05 22.8 0.1 0.0043 17.3 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_14 PF13173.6 VBB25946.1 - 0.00022 21.3 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 VBB25946.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 VBB25946.1 - 0.0013 18.2 0.0 0.26 10.7 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 VBB25946.1 - 0.0013 19.1 0.0 0.0034 17.7 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_lid_3 PF17862.1 VBB25946.1 - 0.0017 18.1 0.1 0.0034 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain NACHT PF05729.12 VBB25946.1 - 0.0039 17.1 0.1 0.061 13.2 0.0 2.2 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 VBB25946.1 - 0.0047 16.3 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 VBB25946.1 - 0.0059 16.6 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 VBB25946.1 - 0.008 15.8 0.2 1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 VBB25946.1 - 0.0083 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 VBB25946.1 - 0.011 15.9 0.0 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.27 VBB25946.1 - 0.024 15.2 0.0 0.078 13.5 0.0 2.0 2 0 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.17 VBB25946.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 VBB25946.1 - 0.036 14.6 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 VBB25946.1 - 0.039 13.5 0.0 0.099 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 VBB25946.1 - 0.044 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.13 VBB25946.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 VBB25946.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain SBDS_C PF09377.10 VBB25946.1 - 0.066 13.2 0.1 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 SBDS protein C-terminal domain AAA_3 PF07726.11 VBB25946.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 VBB25946.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 VBB25946.1 - 0.076 12.9 0.1 0.35 10.8 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 VBB25946.1 - 0.083 12.7 0.2 7.1 6.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Oxidored_nitro PF00148.19 VBB25946.1 - 0.092 11.5 0.0 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Sigma54_activat PF00158.26 VBB25946.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-CCCH PF00642.24 VBB25947.1 - 6.9e-08 32.2 3.8 1.1e-07 31.5 3.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB25947.1 - 1.2e-06 28.4 5.0 2.3e-06 27.5 5.0 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 VBB25947.1 - 1.3e-05 24.8 4.2 2.4e-05 24.0 4.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 VBB25947.1 - 1.5e-05 25.6 0.5 2.5e-05 24.9 0.5 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 VBB25947.1 - 0.0049 17.3 5.9 0.013 16.0 5.9 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Ribosomal_L1 PF00687.21 VBB25948.1 - 3.5e-27 95.5 1.7 2e-26 93.0 0.0 2.8 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Telomere_Sde2_2 PF13297.6 VBB25948.1 - 1.6e-24 85.3 0.1 5e-24 83.7 0.1 1.9 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 VBB25948.1 - 3.1e-15 56.4 2.6 3.1e-15 56.4 2.6 2.6 3 0 0 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain Phage_Arf PF17585.2 VBB25948.1 - 0.092 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Accessory recombination function protein UPF0172 PF03665.13 VBB25948.1 - 0.25 11.3 2.4 0.67 10.0 1.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) G-alpha PF00503.20 VBB25949.1 - 4.2e-108 361.7 10.5 5.3e-108 361.3 10.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB25949.1 - 2.8e-11 43.2 2.2 5.7e-08 32.4 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 VBB25949.1 - 0.0081 16.4 0.3 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 VBB25949.1 - 0.022 14.2 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 VBB25949.1 - 0.04 13.5 0.6 2.3 7.8 0.0 2.5 2 1 0 2 2 2 0 Ras family Sulfotransfer_1 PF00685.27 VBB25950.1 - 4.1e-30 105.2 0.3 7.4e-17 61.7 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 VBB25950.1 - 0.0006 20.3 0.0 0.065 13.6 0.0 2.5 1 1 1 2 2 2 1 Sulfotransferase family MCLC PF05934.11 VBB25950.1 - 0.053 12.3 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Pre-PUA PF17832.1 VBB25951.1 - 0.042 14.5 0.5 0.13 13.0 0.5 1.9 1 0 0 1 1 1 0 Pre-PUA-like domain Pkinase_Tyr PF07714.17 VBB25952.1 - 5.3e-89 297.9 0.0 7.3e-89 297.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB25952.1 - 7.8e-37 127.1 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 VBB25952.1 - 2.8e-22 79.9 17.4 4.9e-22 79.0 17.4 1.3 1 0 0 1 1 1 1 Glycine rich protein MAM PF00629.23 VBB25952.1 - 5e-13 49.3 0.1 1e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Pkinase_fungal PF17667.1 VBB25952.1 - 0.025 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 VBB25952.1 - 0.2 10.9 0.0 17 4.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 VBB25953.1 - 9e-10 38.4 1.7 1.4e-09 37.7 1.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB25953.1 - 3.5e-05 23.2 0.4 5.1e-05 22.7 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB25953.1 - 0.02 13.7 0.1 0.02 13.7 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase MBOAT PF03062.19 VBB25954.1 - 6.8e-26 91.4 30.9 1.2e-25 90.7 30.9 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 VBB25954.1 - 0.41 10.9 11.3 0.097 12.9 7.4 2.0 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family PPI_Ypi1 PF07491.11 VBB25956.1 - 5e-16 58.3 0.4 8.9e-16 57.5 0.4 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor Pox_A_type_inc PF04508.12 VBB25957.1 - 0.7 9.8 5.8 17 5.4 0.5 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat LBP_BPI_CETP_C PF02886.17 VBB25958.1 - 9.9e-17 61.2 0.0 2.3e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain DUF4667 PF15700.5 VBB25958.1 - 0.13 12.3 1.7 0.2 11.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SNF2_N PF00176.23 VBB25959.1 - 2.7e-71 240.1 0.9 2.7e-71 240.1 0.9 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 VBB25959.1 - 7.5e-22 77.2 0.2 2.9e-21 75.3 0.2 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 VBB25959.1 - 1.6e-19 70.3 4.4 7.3e-19 68.1 0.0 3.8 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.13 VBB25959.1 - 1.7e-16 60.3 16.5 1.7e-16 60.3 16.5 4.3 4 0 0 4 4 4 1 HSA QLQ PF08880.11 VBB25959.1 - 4e-07 29.7 0.6 4e-07 29.7 0.6 2.0 2 0 0 2 2 2 1 QLQ BRK PF07533.16 VBB25959.1 - 2.1e-05 24.0 0.0 5.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 BRK domain DEAD PF00270.29 VBB25959.1 - 9.5e-05 22.2 0.0 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ric8 PF10165.9 VBB25960.1 - 1.3e-94 317.9 0.8 1.8e-94 317.4 0.8 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn EF-hand_3 PF09069.11 VBB25960.1 - 0.069 13.6 0.8 0.55 10.7 0.1 2.6 2 0 0 2 2 2 0 EF-hand CIA30 PF08547.12 VBB25961.1 - 8.1e-32 110.5 0.0 1.3e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RNase_T PF00929.24 VBB25961.1 - 9.1e-11 42.6 0.3 3.9e-10 40.5 0.1 2.3 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.22 VBB25962.1 - 3.8e-17 61.9 0.1 5.2e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 VBB25962.1 - 0.0085 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain RRM_1 PF00076.22 VBB25963.1 - 5.1e-13 48.6 0.2 1.2e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRF-TF PF00319.18 VBB25964.1 - 1.4e-19 69.3 0.1 2.5e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Amino_oxidase PF01593.24 VBB25965.1 - 4.6e-11 42.7 0.0 4.1e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 VBB25965.1 - 1e-06 28.8 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 VBB25965.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lustrin_cystein PF14625.6 VBB25966.1 - 1.8e-06 28.2 4.4 2.9e-06 27.5 4.4 1.3 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain RasGEF_N_2 PF14663.6 VBB25967.1 - 0.0059 17.0 3.7 1.9 8.9 0.0 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain IBN_N PF03810.19 VBB25967.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.3 2 0 0 2 2 2 0 Importin-beta N-terminal domain Lyase_1 PF00206.20 VBB25968.1 - 8.3e-121 403.2 0.0 1.1e-120 402.8 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 VBB25968.1 - 8.4e-28 96.6 0.9 4.3e-27 94.3 0.1 2.4 2 0 0 2 2 2 1 Fumarase C C-terminus Kinesin PF00225.23 VBB25969.1 - 1.4e-78 264.2 2.5 1.4e-78 264.2 2.5 3.4 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 VBB25969.1 - 2.8e-06 27.3 4.1 0.025 14.5 0.3 3.6 3 0 0 3 3 3 2 Microtubule binding DUF4718 PF15842.5 VBB25969.1 - 0.0096 15.7 0.6 0.037 13.8 0.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4718) Rep_fac_C PF08542.11 VBB25969.1 - 0.014 15.8 0.2 0.096 13.1 0.2 2.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF3800 PF12686.7 VBB25969.1 - 0.47 11.1 1.7 88 3.8 1.8 4.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) SAM_Exu PF18609.1 VBB25969.1 - 0.64 10.1 13.8 2.1 8.5 2.4 5.0 4 0 0 4 4 4 0 Exuperantia SAM-like domain Elf4 PF07011.11 VBB25969.1 - 2.4 8.1 7.7 0.43 10.5 0.4 3.2 3 0 0 3 3 3 0 Early Flowering 4 domain DEAD PF00270.29 VBB25970.1 - 1.9e-16 60.3 0.0 4.5e-16 59.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB25970.1 - 6.4e-14 52.2 0.2 6e-12 45.9 0.0 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB25970.1 - 2.9e-07 30.7 0.0 1.8e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 VBB25970.1 - 0.021 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Homeodomain PF00046.29 VBB25971.1 - 3.5e-21 74.8 3.3 6.5e-21 73.9 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB25971.1 - 0.024 14.6 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DNA_pol_A PF00476.20 VBB25972.1 - 7.8e-98 328.0 0.0 7.8e-98 328.0 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family A HHH_5 PF14520.6 VBB25972.1 - 0.0065 17.0 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain G10 PF01125.17 VBB25973.1 - 2.3e-58 196.1 1.9 2.7e-58 195.9 1.9 1.0 1 0 0 1 1 1 1 G10 protein Ribosomal_L21e PF01157.18 VBB25974.1 - 1.7e-46 156.2 3.9 2.8e-46 155.5 3.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e OHA PF14418.6 VBB25974.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain PRP3 PF08572.10 VBB25975.1 - 5.9e-51 173.3 3.3 7.2e-27 94.6 2.1 3.6 3 2 1 4 4 4 2 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 VBB25975.1 - 1e-39 136.0 0.8 1e-39 136.0 0.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PulG PF11773.8 VBB25975.1 - 0.044 13.6 0.1 0.044 13.6 0.1 3.1 2 1 1 3 3 3 0 Type II secretory pathway pseudopilin DUF3713 PF12506.8 VBB25975.1 - 5.3 7.4 7.5 18 5.7 1.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF1192 PF06698.11 VBB25976.1 - 0.24 11.5 0.3 0.24 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IP_trans PF02121.18 VBB25977.1 - 1.7e-69 234.2 0.2 2.5e-69 233.6 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 VBB25977.1 - 9.4e-21 75.0 7.6 1.3e-13 51.7 0.2 2.8 2 1 1 3 3 3 2 DDHD domain Nipped-B_C PF12830.7 VBB25977.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus NMT_C PF02799.15 VBB25978.1 - 8e-75 250.9 0.4 1.2e-74 250.4 0.4 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 VBB25978.1 - 2e-73 245.5 0.0 3.7e-73 244.7 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 VBB25978.1 - 0.00076 19.7 0.1 0.0025 18.0 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 VBB25978.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FUN14 PF04930.15 VBB25978.1 - 0.07 13.6 0.0 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 FUN14 family Synaptobrevin PF00957.21 VBB25979.1 - 8e-13 48.0 0.1 1.3e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 VBB25979.1 - 8.8e-13 48.1 0.1 1.7e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain ALG11_N PF15924.5 VBB25980.1 - 1.3e-86 290.0 1.4 2.2e-86 289.3 1.4 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 VBB25980.1 - 2.2e-22 79.4 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 VBB25980.1 - 1.6e-08 35.1 0.0 3.6e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 VBB25980.1 - 1.2e-05 25.4 0.2 5.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Mpp10 PF04006.12 VBB25983.1 - 1.4e-102 344.2 53.3 1.4e-102 344.2 53.3 2.2 2 0 0 2 2 2 1 Mpp10 protein LRR_8 PF13855.6 VBB25985.1 - 3.2e-59 196.6 68.8 8.3e-16 57.5 7.6 7.0 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 VBB25985.1 - 2.8e-36 122.9 51.7 3.8e-07 30.3 1.8 8.7 6 3 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB25985.1 - 9.1e-21 74.1 0.0 6.2e-07 29.4 0.0 3.4 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 VBB25985.1 - 2.8e-20 69.7 46.9 0.59 10.9 0.1 13.6 12 2 1 13 13 13 9 Leucine Rich Repeat LRR_9 PF14580.6 VBB25985.1 - 1.7e-10 40.7 17.9 2.5e-05 23.9 2.3 5.0 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 VBB25985.1 - 3.4e-10 39.2 54.9 0.51 10.5 0.3 13.6 12 1 2 14 14 14 6 Leucine Rich repeat RACo_linker PF17650.1 VBB25985.1 - 0.068 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 RACo linker region MFS_1 PF07690.16 VBB25986.1 - 9.2e-32 110.3 31.2 2.6e-29 102.3 12.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB25986.1 - 0.002 17.1 5.8 0.002 17.1 5.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Spectrin PF00435.21 VBB25988.1 - 2.1e-254 825.3 207.5 5.8e-17 62.1 4.0 19.4 19 0 0 19 19 19 19 Spectrin repeat PH_9 PF15410.6 VBB25988.1 - 1.1e-13 51.6 0.0 7.4e-13 48.9 0.0 2.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 VBB25988.1 - 7e-12 45.8 0.1 2.9e-11 43.8 0.1 2.2 1 0 0 1 1 1 1 PH domain ABC_tran_CTD PF16326.5 VBB25988.1 - 0.0075 16.5 2.8 0.0075 16.5 2.8 16.1 17 3 1 18 18 18 2 ABC transporter C-terminal domain HisKA_2 PF07568.12 VBB25988.1 - 0.063 13.4 4.5 2.5 8.2 0.9 4.4 3 0 0 3 3 3 0 Histidine kinase Herpes_UL69 PF05459.12 VBB25988.1 - 1.2 8.5 6.9 0.29 10.5 0.1 3.4 4 0 0 4 4 4 0 Herpesvirus transcriptional regulator family CDC73_N PF16050.5 VBB25989.1 - 9.5e-64 215.5 2.3 9.5e-64 215.5 2.3 1.4 2 0 0 2 2 2 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 VBB25989.1 - 4.7e-49 166.1 0.2 8.6e-49 165.2 0.2 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal KAP_NTPase PF07693.14 VBB25990.1 - 1.2e-90 304.1 0.1 1.9e-90 303.4 0.1 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.7 VBB25990.1 - 3.9e-59 197.2 2.1 1.9e-15 57.2 0.1 6.5 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB25990.1 - 2.2e-49 165.2 5.0 2e-10 41.0 0.1 9.6 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 VBB25990.1 - 2.9e-44 147.6 1.9 0.0026 18.1 0.0 11.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 VBB25990.1 - 3.8e-40 135.4 11.8 4.2e-09 36.5 0.1 8.4 2 1 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB25990.1 - 7.8e-38 124.2 7.0 0.00027 21.1 0.0 12.1 11 0 0 11 11 11 9 Ankyrin repeat PUB_1 PF18486.1 VBB25990.1 - 0.072 13.0 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain PT PF04886.12 VBB25990.1 - 0.13 11.8 0.4 0.23 11.0 0.4 1.2 1 0 0 1 1 1 0 PT repeat DUF3810 PF12725.7 VBB25990.1 - 1 8.6 9.1 0.59 9.4 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) TM231 PF10149.9 VBB25991.1 - 1.4e-37 129.7 0.0 1.5e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 FG-GAP PF01839.23 VBB25991.1 - 0.56 10.4 1.6 1 9.5 1.6 1.4 1 0 0 1 1 1 0 FG-GAP repeat Trans_reg_C PF00486.28 VBB25992.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Aquarius_N PF16399.5 VBB25993.1 - 1.6e-271 902.9 6.6 2.4e-271 902.4 6.6 1.3 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 VBB25993.1 - 3.4e-28 99.1 0.0 2.1e-13 50.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 VBB25993.1 - 3.6e-28 98.6 0.0 2.2e-27 96.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 VBB25993.1 - 4.5e-08 33.6 0.0 2.1e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 VBB25993.1 - 6e-06 26.1 0.0 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 VBB25993.1 - 8.5e-05 22.6 0.0 8.5e-05 22.6 0.0 2.2 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB25993.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 VBB25993.1 - 0.0049 17.3 0.0 0.055 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 VBB25993.1 - 0.012 14.8 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 VBB25993.1 - 0.018 15.4 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 VBB25993.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 VBB25993.1 - 0.019 14.2 0.7 0.039 13.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 VBB25993.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 VBB25993.1 - 0.026 14.8 0.0 0.16 12.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 VBB25993.1 - 0.039 13.4 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TCTP PF00838.17 VBB25993.1 - 0.06 13.7 0.5 0.14 12.5 0.5 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein AAA_25 PF13481.6 VBB25993.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 VBB25993.1 - 0.088 11.8 2.4 4.9 6.1 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Viral_helicase1 PF01443.18 VBB25993.1 - 0.14 11.9 0.0 3.4 7.4 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase zf-C2H2_4 PF13894.6 VBB25994.1 - 3.3e-13 49.3 52.2 0.00016 22.2 0.2 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB25994.1 - 7.9e-11 41.8 41.8 0.0042 17.5 1.6 6.8 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 VBB25994.1 - 3.4e-08 33.6 30.3 0.036 14.4 0.9 6.5 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 VBB25994.1 - 9.1e-07 29.0 40.3 0.013 15.9 1.2 6.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 VBB25994.1 - 0.00097 19.1 1.8 0.00097 19.1 1.8 6.2 6 1 1 7 7 6 4 C2H2-type zinc finger zf_Hakai PF18408.1 VBB25994.1 - 0.015 15.0 19.1 0.055 13.2 0.1 4.6 5 0 0 5 5 5 0 C2H2 Hakai zinc finger domain Zn-C2H2_12 PF18112.1 VBB25994.1 - 0.044 14.2 0.0 0.044 14.2 0.0 4.0 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Zn_Tnp_IS1595 PF12760.7 VBB25994.1 - 0.051 13.6 23.1 0.17 11.9 0.5 4.4 4 0 0 4 4 4 0 Transposase zinc-ribbon domain PX PF00787.24 VBB25994.1 - 0.071 13.1 1.2 0.15 12.1 0.6 1.8 1 1 0 1 1 1 0 PX domain PHD_4 PF16866.5 VBB25994.1 - 0.14 12.2 9.8 1.7 8.8 0.9 3.9 3 0 0 3 3 3 0 PHD-finger zf-C2HC_2 PF13913.6 VBB25994.1 - 9.8 6.2 21.4 13 5.8 0.1 6.4 6 0 0 6 6 6 0 zinc-finger of a C2HC-type tRNA-synt_1b PF00579.25 VBB25995.1 - 1.2e-19 70.8 0.0 8.8e-12 44.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Sushi PF00084.20 VBB25996.1 - 2.7e-05 24.7 2.6 0.0076 16.8 0.2 2.6 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) SWI-SNF_Ssr4 PF08549.10 VBB25996.1 - 4.6 5.8 19.2 5.8 5.4 19.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) TBCC PF07986.12 VBB25997.1 - 0.2 11.4 5.1 0.32 10.8 5.1 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C GREB1 PF15782.5 VBB25997.1 - 0.47 7.5 7.9 0.54 7.3 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NOA36 PF06524.12 VBB25998.1 - 0.0082 15.5 7.1 0.0082 15.5 7.1 1.4 2 0 0 2 2 2 1 NOA36 protein SpoIIIAH PF12685.7 VBB25998.1 - 0.11 12.3 3.9 0.17 11.7 3.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 VBB25998.1 - 6.3 5.0 10.8 7.9 4.6 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 VBB25998.1 - 7.7 4.5 12.3 11 3.9 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Adap_comp_sub PF00928.21 VBB26001.1 - 9e-59 199.0 0.1 3.4e-58 197.1 0.1 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Ion_trans_2 PF07885.16 VBB26001.1 - 4.1e-36 122.8 24.0 2.4e-18 65.9 12.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB26001.1 - 6.3e-09 35.4 17.4 0.00013 21.3 1.2 2.3 2 0 0 2 2 2 2 Ion transport protein Clat_adaptor_s PF01217.20 VBB26001.1 - 0.00053 19.9 0.7 0.0011 19.0 0.7 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_9 PF14580.6 VBB26002.1 - 3.7e-09 36.3 1.6 0.00025 20.6 0.1 3.2 1 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 VBB26002.1 - 1.9e-08 34.5 14.8 0.018 15.4 0.1 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB26002.1 - 0.0013 18.6 2.9 33 4.9 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Ubiquitin_2 PF14560.6 VBB26002.1 - 0.0013 19.1 0.0 0.0046 17.4 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 VBB26002.1 - 0.0025 17.5 0.0 0.016 15.0 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin family LRR_8 PF13855.6 VBB26002.1 - 0.071 12.9 17.2 0.12 12.1 0.3 4.2 4 2 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 VBB26002.1 - 0.49 11.1 13.2 6.9 7.6 0.2 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat SAM_1 PF00536.30 VBB26004.1 - 8.3e-07 29.4 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB26004.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HDC PF02329.16 VBB26004.1 - 0.02 13.9 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine carboxylase PI chain DUF4378 PF14309.6 VBB26004.1 - 0.072 13.5 0.7 0.18 12.2 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) SAM_Ste50p PF09235.10 VBB26004.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Vps55 PF04133.14 VBB26005.1 - 7.2e-33 113.0 12.2 8.4e-33 112.8 12.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 US6 PF17616.2 VBB26005.1 - 0.35 10.8 0.1 0.35 10.8 0.1 2.1 2 1 0 2 2 2 0 Viral unique short region 6 Ank_2 PF12796.7 VBB26006.1 - 3.2e-13 50.1 2.1 2.7e-12 47.1 2.2 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) BRCT_2 PF16589.5 VBB26006.1 - 1e-10 41.8 0.1 5.3e-06 26.8 0.0 3.4 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Ank_4 PF13637.6 VBB26006.1 - 7e-10 39.2 6.0 1e-06 29.2 0.6 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB26006.1 - 3.1e-09 36.9 1.2 0.00013 22.2 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB26006.1 - 4.6e-07 29.6 1.6 0.026 15.1 0.4 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 VBB26006.1 - 4.9e-06 26.8 2.6 0.14 12.7 1.3 3.1 2 0 0 2 2 2 2 Ankyrin repeat MFS_1 PF07690.16 VBB26006.1 - 5.9e-06 25.4 39.5 0.00023 20.2 25.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily BRCT PF00533.26 VBB26006.1 - 0.0073 16.7 1.5 0.074 13.4 0.1 3.3 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 VBB26006.1 - 0.0076 16.1 0.2 0.14 12.1 0.0 2.8 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain DUF2721 PF11026.8 VBB26006.1 - 1.9 8.4 5.3 1.5 8.7 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Trypsin PF00089.26 VBB26007.1 - 6e-47 160.3 0.1 8.7e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S6 PF02395.16 VBB26007.1 - 0.01 13.9 0.0 0.014 13.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease NICE-1 PF15845.5 VBB26007.1 - 0.047 14.5 3.4 3 8.7 1.6 2.9 3 0 0 3 3 3 0 Cysteine-rich C-terminal 1 family AP_endonuc_2 PF01261.24 VBB26008.1 - 2.3e-34 118.7 0.0 3.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MBOAT PF03062.19 VBB26008.1 - 4.2e-29 102.0 10.7 4.2e-29 102.0 10.7 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family HpaB_N PF11794.8 VBB26008.1 - 0.047 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal UCH PF00443.29 VBB26009.1 - 2.7e-46 158.2 1.2 2.7e-46 158.2 1.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB26009.1 - 1e-35 123.9 3.1 2.5e-35 122.6 3.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3915 PF13054.6 VBB26011.1 - 0.022 14.7 0.5 0.022 14.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 VBB26011.1 - 8.1 4.6 7.3 10 4.3 7.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Y_phosphatase PF00102.27 VBB26012.1 - 6.4e-130 431.8 2.9 4.5e-54 183.5 0.0 3.4 3 0 0 3 3 3 3 Protein-tyrosine phosphatase fn3 PF00041.21 VBB26012.1 - 1.7e-07 31.5 0.0 0.023 15.1 0.1 3.6 2 1 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 VBB26012.1 - 5.1e-05 23.4 0.0 0.00024 21.3 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Y_phosphatase3 PF13350.6 VBB26012.1 - 0.00023 21.2 0.0 0.0033 17.4 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 VBB26012.1 - 0.0016 18.3 0.1 0.0068 16.2 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB26012.1 - 0.0028 17.8 0.0 0.039 14.1 0.0 2.6 2 0 0 2 2 2 1 Inositol hexakisphosphate ig PF00047.25 VBB26012.1 - 0.022 14.9 0.1 0.061 13.5 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 VBB26012.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain Helicase_C_2 PF13307.6 VBB26013.1 - 9.5e-52 175.6 0.0 2.1e-51 174.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 VBB26013.1 - 4.9e-39 133.8 0.3 1.4e-38 132.3 0.3 1.9 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 VBB26013.1 - 3.8e-05 23.8 4.1 0.00071 19.6 0.2 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 VBB26013.1 - 0.031 14.5 0.0 11 6.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 VBB26013.1 - 0.09 12.3 0.0 0.66 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 VBB26013.1 - 0.11 11.9 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF5492 PF17596.2 VBB26013.1 - 0.42 11.0 2.0 1.3 9.4 2.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5492) DUF2262 PF10020.9 VBB26013.1 - 2.7 8.4 7.2 7.1 7.0 7.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) LBP_BPI_CETP_C PF02886.17 VBB26014.1 - 5.7e-21 75.1 0.0 1.9e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 VBB26014.1 - 5.9e-14 52.0 3.5 4.8e-13 49.1 0.3 2.9 3 0 0 3 3 3 1 LBP / BPI / CETP family, N-terminal domain zf-C2H2 PF00096.26 VBB26015.1 - 1.7e-15 56.5 13.3 7.3e-07 29.3 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26015.1 - 1.8e-14 53.1 13.6 1.3e-05 25.6 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB26015.1 - 2e-13 50.1 18.0 2.9e-10 40.1 0.2 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.7 VBB26015.1 - 1.7e-06 28.2 7.1 0.021 15.2 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 VBB26015.1 - 2.3e-05 24.6 10.8 0.001 19.3 4.2 2.9 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 VBB26015.1 - 0.00012 22.3 3.8 0.12 12.7 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 VBB26015.1 - 0.0002 21.0 7.1 0.16 11.8 4.4 3.3 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 VBB26015.1 - 0.00037 20.8 7.9 0.85 10.0 1.1 3.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 VBB26015.1 - 0.00082 19.8 7.9 0.045 14.2 0.1 3.9 3 1 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain DUF3797 PF12677.7 VBB26015.1 - 0.0053 16.6 3.5 0.22 11.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3797) C1_4 PF07975.12 VBB26015.1 - 0.0077 16.4 4.6 0.33 11.2 0.0 3.0 2 1 1 3 3 3 1 TFIIH C1-like domain SSP160 PF06933.11 VBB26015.1 - 0.0097 14.2 5.6 0.01 14.1 5.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 zf-C2H2_6 PF13912.6 VBB26015.1 - 0.011 15.7 2.7 0.011 15.7 2.7 3.9 3 2 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 VBB26015.1 - 0.014 16.1 8.7 1.1 10.0 0.4 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 VBB26015.1 - 0.015 15.2 5.2 3.5 7.6 0.0 3.5 3 1 0 3 3 3 0 zinc-finger of a C2HC-type GAGA PF09237.11 VBB26015.1 - 0.039 13.8 0.3 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 GAGA factor CxC5 PF18718.1 VBB26015.1 - 0.047 13.8 6.8 0.41 10.7 2.1 2.2 1 1 1 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases zf-C6H2 PF15801.5 VBB26015.1 - 0.05 13.9 7.0 3.8 7.9 0.2 3.6 4 0 0 4 4 3 0 zf-MYND-like zinc finger, mRNA-binding zf-HYPF PF07503.12 VBB26015.1 - 0.078 12.8 5.5 3.7 7.4 0.0 3.4 4 0 0 4 4 4 0 HypF finger Prok-RING_1 PF14446.6 VBB26015.1 - 0.089 12.7 5.5 9.3 6.3 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 VBB26015.1 - 0.1 12.7 6.4 1.5 9.0 2.8 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 VBB26015.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.4 4 0 0 4 4 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 VBB26015.1 - 0.16 12.0 8.0 6 7.0 0.1 3.6 2 1 1 3 3 3 0 BED zinc finger CxC7 PF18866.1 VBB26015.1 - 0.31 11.2 3.0 8.4 6.6 0.1 3.1 3 0 0 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases DUF2225 PF09986.9 VBB26015.1 - 0.32 10.7 7.5 2.4 7.8 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.16 VBB26015.1 - 0.33 11.1 7.7 19 5.5 0.7 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.6 VBB26015.1 - 0.49 10.4 10.7 12 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Anti-TRAP PF15777.5 VBB26015.1 - 0.52 10.3 3.8 1.8 8.6 0.1 2.9 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-C2H2_9 PF16293.5 VBB26015.1 - 0.62 10.0 7.0 5 7.0 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 VBB26015.1 - 1.2 9.4 5.6 11 6.2 2.7 2.9 2 1 0 2 2 2 0 KIAA1045 RING finger zf-ribbon_3 PF13248.6 VBB26015.1 - 2.2 7.8 9.6 2.3 7.7 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon domain DUF2256 PF10013.9 VBB26015.1 - 2.8 8.1 8.1 8.1 6.7 0.8 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 VBB26015.1 - 3.6 8.1 9.4 3.4 8.2 0.4 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.6 VBB26015.1 - 3.8 7.6 9.5 5.6 7.0 0.3 3.0 1 1 1 3 3 3 0 CpXC protein Yippee-Mis18 PF03226.14 VBB26015.1 - 4.5 7.5 11.9 38 4.5 0.1 2.6 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TFIIS_C PF01096.18 VBB26015.1 - 5.8 6.9 8.4 21 5.1 0.6 3.4 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zinc_ribbon_15 PF17032.5 VBB26015.1 - 7.8 7.3 10.1 18 6.2 1.8 3.1 1 1 2 3 3 3 0 zinc-ribbon family zf-RING_5 PF14634.6 VBB26015.1 - 8.6 6.4 10.9 21 5.2 6.3 2.8 2 1 0 2 2 2 0 zinc-RING finger domain XPA_N PF01286.18 VBB26015.1 - 9.3 6.4 8.0 4.9 7.3 0.3 2.7 3 0 0 3 3 2 0 XPA protein N-terminal HTH_9 PF08221.11 VBB26016.1 - 1.9e-19 69.5 2.1 7.5e-10 38.8 0.0 3.5 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 VBB26016.1 - 7.2e-19 68.5 0.0 3.5e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 VBB26016.1 - 1.8e-06 27.8 3.0 0.00012 21.8 0.5 4.0 4 1 0 4 4 4 1 TFIIE alpha subunit GntR PF00392.21 VBB26016.1 - 0.011 15.4 0.1 5.6 6.7 0.0 3.6 4 0 0 4 4 4 0 Bacterial regulatory proteins, gntR family Ribosomal_S10 PF00338.22 VBB26019.1 - 9.1e-18 64.3 0.6 2.9e-17 62.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Zea_mays_MuDR PF05928.11 VBB26019.1 - 0.017 14.8 0.1 0.063 12.9 0.0 1.8 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) SieB PF14163.6 VBB26019.1 - 0.053 13.0 1.0 0.55 9.7 0.1 2.4 2 1 0 2 2 2 0 Super-infection exclusion protein B GGACT PF06094.12 VBB26020.1 - 5.1e-25 88.4 0.0 6.8e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 VBB26020.1 - 1.1e-07 32.1 0.1 2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 AIG2-like family PXA PF02194.15 VBB26021.1 - 0.016 15.2 1.9 1.1 9.3 0.1 2.7 2 1 0 2 2 2 0 PXA domain Pkinase PF00069.25 VBB26022.1 - 2.9e-11 43.3 0.0 3.5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26022.1 - 3.6e-06 26.5 0.0 4.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB26022.1 - 0.00072 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 VBB26022.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Fructosamin_kin PF03881.14 VBB26022.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase APH PF01636.23 VBB26022.1 - 0.16 11.8 0.1 1.5 8.7 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Neur_chan_LBD PF02931.23 VBB26023.1 - 3.4e-10 39.7 1.6 0.00033 20.2 0.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain HSP20 PF00011.21 VBB26024.1 - 3.3e-21 75.3 0.7 4.2e-21 75.0 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Cadherin_3 PF16184.5 VBB26025.1 - 2.3e-144 471.9 26.7 1.2e-19 70.3 0.0 15.3 15 0 0 15 15 15 15 Cadherin-like CLN6 PF15156.6 VBB26025.1 - 0.069 12.4 0.2 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Ceroid-lipofuscinosis neuronal protein 6 Myosin_head PF00063.21 VBB26026.1 - 3.9e-198 659.9 20.8 1.5e-142 476.3 8.8 3.2 2 1 1 3 3 3 3 Myosin head (motor domain) RhoGAP PF00620.27 VBB26026.1 - 2e-41 141.3 2.8 1.7e-40 138.3 1.1 2.8 2 0 0 2 2 2 1 RhoGAP domain IQ PF00612.27 VBB26026.1 - 1.9e-05 24.0 15.4 0.15 11.9 2.8 4.3 3 0 0 3 3 3 3 IQ calmodulin-binding motif RA PF00788.23 VBB26026.1 - 0.00016 22.2 0.3 0.00072 20.1 0.1 2.4 2 0 0 2 2 1 1 Ras association (RalGDS/AF-6) domain AAA_22 PF13401.6 VBB26026.1 - 0.00057 20.2 0.1 0.024 14.9 0.0 3.5 2 0 0 2 2 2 1 AAA domain CAP-ZIP_m PF15255.6 VBB26026.1 - 0.00061 20.1 1.2 0.0011 19.2 0.1 2.0 2 0 0 2 2 2 1 WASH complex subunit CAP-Z interacting, central region AAA_16 PF13191.6 VBB26026.1 - 0.023 15.1 1.7 0.18 12.2 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 VBB26026.1 - 0.029 13.4 0.9 0.098 11.7 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AviRa PF11599.8 VBB26026.1 - 0.098 12.1 0.3 0.36 10.2 0.3 2.0 1 0 0 1 1 1 0 RRNA methyltransferase AviRa AAA_28 PF13521.6 VBB26026.1 - 0.43 10.8 2.5 18 5.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 VBB26026.1 - 1.3 9.6 6.7 2.2 8.8 2.7 3.4 2 1 0 2 2 2 0 ABC transporter Patched PF02460.18 VBB26027.1 - 3.5e-75 253.7 24.3 6e-34 117.3 13.5 3.1 2 1 1 3 3 3 3 Patched family Sterol-sensing PF12349.8 VBB26027.1 - 7.2e-18 64.9 8.2 7.2e-18 64.9 8.2 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 VBB26028.1 - 5.6e-67 226.5 8.3 7.2e-67 226.2 8.3 1.1 1 0 0 1 1 1 1 Patched family SecD_SecF PF02355.16 VBB26028.1 - 5.3e-08 32.5 2.9 1.1e-07 31.5 2.7 1.5 1 1 0 1 1 1 1 Protein export membrane protein EF_assoc_1 PF08355.12 VBB26028.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 EF hand associated ACR_tran PF00873.19 VBB26028.1 - 0.053 11.2 3.2 0.068 10.8 3.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family P66_CC PF16563.5 VBB26029.1 - 2.5e-14 52.6 11.7 2.5e-14 52.6 11.7 3.1 4 0 0 4 4 4 1 Coiled-coil and interaction region of P66A and P66B with MBD2 GATA PF00320.27 VBB26029.1 - 0.0009 18.8 0.3 0.0023 17.5 0.3 1.8 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 VBB26029.1 - 0.02 15.0 0.2 0.047 13.8 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_2 PF12674.7 VBB26029.1 - 0.48 11.1 2.8 0.63 10.7 0.2 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain VPS9 PF02204.18 VBB26030.1 - 4.7e-11 42.8 0.0 8.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 VBB26030.1 - 0.0011 19.5 0.0 0.0027 18.3 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain EF_TS PF00889.19 VBB26031.1 - 7.8e-29 100.8 0.0 1.5e-28 99.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor TS Linker_histone PF00538.19 VBB26031.1 - 0.00079 19.7 0.1 0.42 11.0 0.0 2.7 2 0 0 2 2 2 2 linker histone H1 and H5 family Calsequestrin PF01216.17 VBB26031.1 - 0.0052 15.9 0.0 0.007 15.4 0.0 1.1 1 0 0 1 1 1 1 Calsequestrin Condensation PF00668.20 VBB26033.1 - 2.6e-120 402.2 53.5 2.4e-46 158.4 11.2 8.2 6 2 0 6 6 6 5 Condensation domain AMP-binding PF00501.28 VBB26033.1 - 6.8e-102 341.2 0.0 4.8e-57 193.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 VBB26033.1 - 1.4e-40 137.5 0.1 9.1e-09 35.5 0.0 6.5 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 VBB26033.1 - 3.9e-16 59.8 0.0 2.1e-07 31.8 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 VBB26033.1 - 1e-07 32.3 0.0 2.7e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Ist1 PF03398.14 VBB26034.1 - 2.8e-60 203.0 2.4 3.7e-60 202.6 2.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway OB_NTP_bind PF07717.16 VBB26035.1 - 4.1e-26 91.2 0.0 1e-25 89.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 VBB26035.1 - 2.6e-23 82.3 0.1 2.6e-23 82.3 0.1 3.2 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 VBB26035.1 - 4.3e-14 52.8 0.0 1.9e-13 50.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 VBB26035.1 - 2.2e-12 47.2 0.3 6.6e-12 45.6 0.3 1.9 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 VBB26035.1 - 0.00022 21.1 0.2 0.00051 19.9 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 VBB26035.1 - 0.00062 18.9 0.3 0.003 16.7 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 VBB26035.1 - 0.00077 19.7 0.0 0.0026 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 VBB26035.1 - 0.0066 16.2 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 VBB26035.1 - 0.01 16.2 0.2 0.026 14.9 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB26035.1 - 0.056 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Galactosyl_T PF01762.21 VBB26036.1 - 1.2e-35 123.1 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase EF-hand_1 PF00036.32 VBB26037.1 - 1.4e-25 86.9 18.2 2.1e-06 26.8 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB26037.1 - 9.7e-24 83.6 9.5 3.2e-13 49.9 2.7 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB26037.1 - 2.2e-21 73.9 15.2 5.1e-05 22.9 0.3 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 VBB26037.1 - 2.5e-19 67.8 13.5 7.1e-05 22.1 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 VBB26037.1 - 3.2e-15 55.7 13.8 0.00032 20.5 0.6 4.5 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB26037.1 - 1.4e-06 28.6 0.2 0.059 13.7 0.1 2.9 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 VBB26037.1 - 1.5e-05 24.9 6.5 0.019 14.9 0.8 3.3 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 VBB26037.1 - 0.011 15.7 6.9 2.6 7.9 0.2 3.8 1 1 3 4 4 4 0 Caleosin related protein EF-hand_9 PF14658.6 VBB26037.1 - 0.012 16.0 1.1 0.067 13.5 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 VBB26037.1 - 5.7 7.2 7.0 2.7e+02 1.9 5.4 3.5 1 1 1 2 2 2 0 Dockerin type I domain NTP_transf_2 PF01909.23 VBB26038.1 - 0.00059 20.1 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 VBB26038.1 - 0.093 12.8 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Collagen PF01391.18 VBB26039.1 - 1.8e-26 91.7 107.0 1.2e-10 41.0 32.9 4.1 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26039.1 - 8.7e-20 70.5 0.4 1.1e-19 70.2 0.4 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain COX14 PF14880.6 VBB26039.1 - 0.53 10.2 2.0 0.8 9.6 2.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly PDZ PF00595.24 VBB26040.1 - 1.2e-05 25.6 1.6 0.00015 22.0 0.3 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB26040.1 - 0.00015 22.0 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB26040.1 - 0.00036 20.3 0.7 0.00068 19.4 0.1 1.8 2 0 0 2 2 2 1 PDZ domain Rhabdo_matrix PF03397.14 VBB26040.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Rhabdovirus matrix protein Pep3_Vps18 PF05131.14 VBB26041.1 - 5.3e-27 94.5 1.4 9e-27 93.7 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 VBB26041.1 - 7.3e-05 22.7 1.4 7.3e-05 22.7 1.4 3.2 4 0 0 4 4 4 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 VBB26041.1 - 0.0001 22.2 2.1 0.00035 20.5 2.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.9 VBB26041.1 - 0.00035 20.8 1.1 0.00035 20.8 1.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 VBB26041.1 - 0.00046 19.7 1.1 0.00046 19.7 1.1 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 VBB26041.1 - 0.0022 18.0 1.3 0.0058 16.6 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB26041.1 - 0.0088 15.9 2.1 0.03 14.2 2.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 VBB26041.1 - 0.011 15.8 1.6 0.026 14.6 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_2 PF13923.6 VBB26041.1 - 0.012 15.4 3.3 0.038 13.8 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB26041.1 - 0.013 15.8 1.8 0.038 14.3 1.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 VBB26041.1 - 0.049 13.4 3.0 0.15 11.9 3.0 1.9 1 0 0 1 1 1 0 RING-like zinc finger KinB_sensor PF16767.5 VBB26041.1 - 0.082 13.4 3.4 0.48 10.9 0.1 2.5 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DivIC PF04977.15 VBB26041.1 - 0.088 12.6 2.0 0.58 10.0 2.0 2.5 1 0 0 1 1 1 0 Septum formation initiator zf-ANAPC11 PF12861.7 VBB26041.1 - 0.1 12.6 0.2 0.32 11.1 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 VBB26041.1 - 2.2 8.7 10.4 0.03 14.6 2.5 2.1 2 0 0 2 2 1 0 Ring finger domain DM PF00751.18 VBB26042.1 - 1.4e-22 79.3 9.3 2.4e-22 78.6 9.3 1.4 1 0 0 1 1 1 1 DM DNA binding domain His_Phos_2 PF00328.22 VBB26043.1 - 9.5e-19 68.0 0.1 8.2e-14 51.7 0.0 3.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2207 PF09972.9 VBB26043.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 VBB26043.1 - 0.016 15.5 0.3 0.03 14.6 0.3 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Gemini_mov PF01708.16 VBB26043.1 - 0.04 13.7 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein TTR-52 PF01060.23 VBB26044.1 - 1.5e-28 99.3 0.0 1.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Cadherin PF00028.17 VBB26046.1 - 7e-181 587.3 25.0 3.3e-18 65.9 0.0 18.1 17 1 1 18 18 18 15 Cadherin domain Laminin_G_2 PF02210.24 VBB26046.1 - 1.8e-23 83.5 0.1 1.5e-14 54.7 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 VBB26046.1 - 1.9e-19 70.2 0.1 2.7e-11 43.8 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Cadherin_2 PF08266.12 VBB26046.1 - 6.5e-10 38.7 0.0 9.4 6.1 0.0 10.1 12 0 0 12 12 12 2 Cadherin-like EGF PF00008.27 VBB26046.1 - 0.00019 21.6 9.8 0.00019 21.6 9.8 5.6 6 0 0 6 6 6 3 EGF-like domain Glyco_hydro2_C5 PF18565.1 VBB26046.1 - 0.13 12.1 0.7 12 5.8 0.0 3.8 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 Cadherin PF00028.17 VBB26047.1 - 3.4e-117 383.2 5.9 1.7e-16 60.4 0.1 16.0 16 1 0 16 16 16 14 Cadherin domain Cadherin_2 PF08266.12 VBB26047.1 - 1.7e-06 27.7 2.8 1.7 8.6 0.0 8.4 11 1 0 11 11 11 2 Cadherin-like RET_CLD1 PF17756.1 VBB26047.1 - 3.1e-06 27.5 1.1 0.47 10.7 0.0 6.6 8 0 0 8 8 8 2 RET Cadherin like domain 1 Cadherin_pro PF08758.11 VBB26047.1 - 0.0074 16.4 0.1 44 4.3 0.0 5.1 6 0 0 6 6 6 1 Cadherin prodomain like V-ATPase_G PF03179.15 VBB26050.1 - 3.6e-37 127.1 19.9 4.3e-37 126.9 19.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Apolipoprotein PF01442.18 VBB26050.1 - 0.04 13.8 13.5 0.045 13.6 13.5 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2001 PF09393.10 VBB26050.1 - 0.052 13.5 1.8 0.067 13.2 1.8 1.2 1 0 0 1 1 1 0 Phage tail tube protein DUF3086 PF11285.8 VBB26050.1 - 0.075 12.1 5.3 0.09 11.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DDRGK PF09756.9 VBB26050.1 - 0.086 12.4 19.4 0.12 12.0 19.4 1.2 1 0 0 1 1 1 0 DDRGK domain V-ATPase_G_2 PF16999.5 VBB26050.1 - 0.28 11.6 16.6 0.35 11.3 16.6 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RabGAP-TBC PF00566.18 VBB26050.1 - 0.6 9.7 5.2 0.84 9.2 5.2 1.3 1 1 0 1 1 1 0 Rab-GTPase-TBC domain DUF4246 PF14033.6 VBB26050.1 - 0.62 9.1 6.8 0.71 8.9 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) FdhE PF04216.12 VBB26050.1 - 1 9.2 7.0 1.2 8.9 7.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Exonuc_VII_L PF02601.15 VBB26050.1 - 1.7 8.1 10.0 1.9 8.0 10.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 VBB26050.1 - 2.5 8.8 12.2 3.6 8.3 7.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3552 PF12072.8 VBB26050.1 - 3.4 7.0 23.9 21 4.4 23.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 VBB26050.1 - 3.7 6.8 10.5 4.6 6.5 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.18 VBB26050.1 - 4.8 7.3 24.5 1.2e+02 2.7 24.3 2.1 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Mitoc_mL59 PF18126.1 VBB26050.1 - 8.5 6.7 10.7 12 6.2 10.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 ubiquitin PF00240.23 VBB26051.1 - 4.1e-06 26.5 0.3 2.6e-05 23.9 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 VBB26051.1 - 5.9e-05 23.4 0.2 0.00031 21.1 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 VBB26051.1 - 0.0097 15.7 0.2 0.058 13.2 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 VBB26051.1 - 0.017 15.2 0.2 0.087 12.9 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain PI3K_rbd PF00794.18 VBB26051.1 - 0.044 13.9 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Tubulin_C PF03953.17 VBB26052.1 - 7e-50 168.4 0.0 9.9e-50 167.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 VBB26052.1 - 2.8e-42 145.2 0.0 9.5e-42 143.4 0.0 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 VBB26052.1 - 0.0004 20.1 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain PEMT PF04191.13 VBB26052.1 - 0.029 14.8 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipid methyltransferase GCFC PF07842.12 VBB26053.1 - 5.8e-12 45.8 0.2 3.1e-10 40.1 0.2 2.8 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein SNARE PF05739.19 VBB26053.1 - 3.3e-05 23.8 1.4 0.00013 21.9 1.4 2.1 1 0 0 1 1 1 1 SNARE domain DUF3137 PF11335.8 VBB26053.1 - 0.01 15.8 0.2 0.037 14.0 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3137) ThrE PF06738.12 VBB26053.1 - 0.023 14.0 0.1 0.05 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF948 PF06103.11 VBB26053.1 - 3.7 7.9 8.8 5.2 7.4 1.4 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DnaJ_C PF01556.18 VBB26054.1 - 8.5e-41 139.5 0.3 1.2e-40 139.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 VBB26054.1 - 4.2e-23 81.2 0.9 6.5e-23 80.6 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 VBB26054.1 - 4.2e-14 52.6 14.8 8e-14 51.8 14.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 VBB26054.1 - 0.026 14.5 14.6 0.072 13.1 4.0 3.1 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 VBB26054.1 - 0.22 11.6 5.6 0.91 9.6 1.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 VBB26054.1 - 2.2 8.3 8.0 4.6 7.3 2.5 2.4 2 0 0 2 2 2 0 zinc-ribbons Cytochrom_c3_2 PF14537.6 VBB26054.1 - 3.3 8.2 6.0 3.1 8.3 1.5 2.3 2 0 0 2 2 2 0 Cytochrome c3 zf-RING_10 PF16685.5 VBB26054.1 - 3.7 7.8 6.9 6.4 7.0 1.7 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 C1_2 PF03107.16 VBB26054.1 - 4.4 7.7 6.3 0.57 10.5 0.4 2.3 2 0 0 2 2 2 0 C1 domain zf-C2H2 PF00096.26 VBB26056.1 - 4.3e-26 89.9 26.9 1.9e-05 24.9 1.5 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26056.1 - 1.2e-21 75.5 25.6 0.00022 21.8 1.4 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB26056.1 - 6.5e-18 64.3 28.3 3.3e-05 24.1 0.2 5.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 VBB26056.1 - 1.8e-12 46.9 26.5 0.0037 17.2 0.7 5.8 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 VBB26056.1 - 2e-09 37.0 18.8 0.062 13.1 0.0 5.3 4 1 1 5 5 5 4 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 VBB26056.1 - 4.7e-07 29.9 13.5 0.085 13.2 0.1 4.7 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 VBB26056.1 - 0.00019 21.5 11.9 0.13 12.4 0.4 4.2 3 2 0 3 3 3 1 Zinc ribbon domain zf_UBZ PF18439.1 VBB26056.1 - 0.0011 18.5 8.4 8.8 6.0 0.1 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 VBB26056.1 - 0.0015 19.2 12.9 0.14 12.9 0.5 3.2 1 1 3 4 4 4 2 zinc-ribbon family zf-C2H2_3rep PF18868.1 VBB26056.1 - 0.0048 17.6 8.9 0.24 12.1 0.1 3.5 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 VBB26056.1 - 0.0048 16.9 9.5 0.29 11.2 0.5 3.2 1 1 2 3 3 3 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 VBB26056.1 - 0.0069 16.3 12.5 0.22 11.5 0.2 3.9 4 0 0 4 4 4 2 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 VBB26056.1 - 0.0095 16.3 18.0 1.7 9.0 1.6 4.8 1 1 4 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 VBB26056.1 - 0.01 15.7 17.7 0.54 10.2 0.2 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 VBB26056.1 - 0.026 14.4 7.3 6.8 6.7 0.1 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 VBB26056.1 - 0.027 14.9 18.1 0.53 10.8 0.2 4.9 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 VBB26056.1 - 0.035 14.2 14.6 1.1 9.4 0.1 4.5 5 0 0 5 5 4 0 XPA protein N-terminal zf-BED PF02892.15 VBB26056.1 - 0.054 13.5 21.9 0.18 11.9 1.5 4.5 2 1 2 4 4 4 0 BED zinc finger zf-MYND PF01753.18 VBB26056.1 - 0.063 13.4 15.6 0.51 10.5 0.8 3.7 2 1 1 3 3 3 0 MYND finger zf_C2H2_13 PF18508.1 VBB26056.1 - 0.1 12.2 5.5 3 7.5 0.0 3.4 3 0 0 3 3 3 0 Zinc finger domain zf-met PF12874.7 VBB26056.1 - 0.16 12.4 22.0 0.74 10.3 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 VBB26056.1 - 0.21 11.5 17.1 30 4.6 0.1 5.7 5 1 0 5 5 5 0 zinc-ribbon domain zf-AN1 PF01428.16 VBB26056.1 - 0.21 11.8 13.2 53 4.1 0.1 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger FYVE PF01363.21 VBB26056.1 - 0.21 11.7 17.7 50 4.1 1.9 4.0 1 1 1 2 2 2 0 FYVE zinc finger Rpr2 PF04032.16 VBB26056.1 - 0.56 10.5 13.2 31 4.9 0.1 3.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_recom PF13408.6 VBB26056.1 - 1.3 9.6 15.5 12 6.5 2.8 3.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF3565 PF12088.8 VBB26056.1 - 1.6 8.8 6.1 23 5.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3565) Sprouty PF05210.13 VBB26056.1 - 1.6 9.1 10.6 2.3 8.6 0.4 3.4 1 1 2 3 3 3 0 Sprouty protein (Spry) C1_4 PF07975.12 VBB26056.1 - 1.7 8.9 12.6 3.6 7.9 0.2 3.6 3 1 1 4 4 3 0 TFIIH C1-like domain zf-ribbon_3 PF13248.6 VBB26056.1 - 2.1 7.9 16.2 17 5.0 0.2 4.8 5 0 0 5 5 5 0 zinc-ribbon domain DUF2256 PF10013.9 VBB26056.1 - 2.3 8.4 15.9 8.1 6.7 0.0 5.4 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 VBB26056.1 - 2.8 8.0 15.3 10 6.2 0.1 4.7 1 1 4 5 5 5 0 CpXC protein TerY_C PF15616.6 VBB26056.1 - 2.9 8.0 8.7 5.5 7.1 0.4 2.6 1 1 2 3 3 3 0 TerY-C metal binding domain zf-C2H2_9 PF16293.5 VBB26056.1 - 3.4 7.6 6.8 4.7 7.1 0.7 3.3 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF3795 PF12675.7 VBB26056.1 - 3.6 8.1 13.3 44 4.6 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) DUF3268 PF11672.8 VBB26056.1 - 3.7 7.9 9.4 2.5 8.4 0.6 2.4 2 1 0 2 2 2 0 zinc-finger-containing domain zf-MYST PF17772.1 VBB26056.1 - 5.1 6.8 9.8 18 5.1 0.4 3.7 4 0 0 4 4 4 0 MYST family zinc finger domain Cript PF10235.9 VBB26056.1 - 5.3 7.7 16.8 13 6.5 0.3 3.9 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT Zn_ribbon_SprT PF17283.2 VBB26056.1 - 6.2 6.8 20.1 0.08 12.9 1.8 4.1 3 1 1 4 4 3 0 SprT-like zinc ribbon domain LIM PF00412.22 VBB26056.1 - 6.7 7.0 18.1 0.76 10.0 3.0 3.4 2 1 1 3 3 3 0 LIM domain ATPase-cat_bd PF12156.8 VBB26056.1 - 8 7.3 9.8 0.3 11.8 1.2 2.4 2 1 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Zona_pellucida PF00100.23 VBB26057.1 - 2.1e-12 47.4 1.6 3.2e-12 46.8 1.6 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Pepsin-I3 PF06394.13 VBB26058.1 - 2.9e-06 27.4 0.1 5.2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain Ku_PK_bind PF08785.11 VBB26058.1 - 0.086 13.0 1.4 2 8.6 0.1 2.2 1 1 1 2 2 2 0 Ku C terminal domain like RRM_1 PF00076.22 VBB26059.1 - 9.2e-08 31.8 0.1 3.5e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 VBB26059.1 - 1.3e-07 30.8 2.7 2.7e-07 29.8 2.7 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others T3SS_needle_F PF09392.10 VBB26059.1 - 0.34 11.1 1.9 0.55 10.5 1.9 1.2 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF C1_2 PF03107.16 VBB26059.1 - 0.38 11.1 4.5 0.14 12.5 1.4 1.8 2 0 0 2 2 2 0 C1 domain zf-Tim10_DDP PF02953.15 VBB26060.1 - 3.8e-22 77.7 2.9 6.1e-22 77.0 2.9 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2605 PF10792.9 VBB26060.1 - 0.015 15.2 1.7 0.053 13.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) ACDC PF14733.6 VBB26060.1 - 0.021 15.1 1.2 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 AP2-coincident C-terminal Condensin2nSMC PF12422.8 VBB26060.1 - 0.028 14.6 1.1 0.37 11.0 0.1 2.0 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit GNAT_acetyltr_2 PF13718.6 VBB26061.1 - 9.2e-89 296.7 0.0 2.4e-88 295.4 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 VBB26061.1 - 4.9e-69 232.6 2.6 7.8e-69 231.9 2.6 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 VBB26061.1 - 6.1e-61 205.3 0.0 1.1e-60 204.5 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 VBB26061.1 - 5.3e-23 80.8 0.0 1.4e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 VBB26061.1 - 0.00048 20.4 0.0 0.0081 16.4 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family AAA_30 PF13604.6 VBB26061.1 - 0.0013 18.5 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Acetyltransf_7 PF13508.7 VBB26061.1 - 0.0044 17.4 0.0 0.026 15.0 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 VBB26061.1 - 0.04 14.3 0.1 2.4 8.5 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain DEAD PF00270.29 VBB26061.1 - 0.1 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase EcoRI_methylase PF13651.6 VBB26062.1 - 0.011 15.0 0.2 0.013 14.7 0.2 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI LRR_8 PF13855.6 VBB26063.1 - 1e-22 79.6 30.8 2.2e-08 33.7 4.1 4.8 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 VBB26063.1 - 2.2e-09 37.4 24.1 0.00017 21.9 1.8 5.3 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB26063.1 - 0.00015 21.9 18.7 4.2 8.3 0.1 6.8 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 VBB26063.1 - 0.00085 19.2 8.0 14 6.1 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 VBB26063.1 - 0.0078 15.7 6.5 0.56 9.7 3.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat Homeodomain PF00046.29 VBB26066.1 - 6.2e-23 80.4 4.5 1.2e-22 79.5 4.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB26066.1 - 0.033 14.1 0.2 0.096 12.6 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain Fez1 PF06818.15 VBB26069.1 - 0.0015 19.0 56.3 0.037 14.5 16.4 4.0 1 1 3 4 4 4 2 Fez1 DUF4201 PF13870.6 VBB26069.1 - 0.0099 15.6 7.7 0.0099 15.6 7.7 5.4 1 1 3 5 5 5 1 Domain of unknown function (DUF4201) BST2 PF16716.5 VBB26069.1 - 0.017 15.7 6.1 0.017 15.7 6.1 5.8 2 2 1 4 4 4 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 VBB26069.1 - 0.032 13.1 66.7 0.23 10.3 14.2 4.1 2 2 2 4 4 4 0 Spc7 kinetochore protein ERM PF00769.19 VBB26069.1 - 0.14 12.0 62.4 0.11 12.4 16.9 3.4 1 1 1 3 3 3 0 Ezrin/radixin/moesin family MDMPI_N PF11716.8 VBB26069.1 - 0.24 12.1 1.0 0.46 11.2 1.0 1.4 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Rpn9_C PF18261.1 VBB26069.1 - 0.55 9.9 3.2 1.6 8.4 3.2 1.8 1 0 0 1 1 1 0 Rpn9 C-terminal helix Lebercilin PF15619.6 VBB26069.1 - 0.56 9.8 63.3 0.032 13.9 14.7 3.8 2 2 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease AKNA PF12443.8 VBB26069.1 - 3.7 8.3 12.5 0.096 13.3 1.0 3.6 3 0 0 3 3 3 0 AT-hook-containing transcription factor AAA_13 PF13166.6 VBB26069.1 - 6.9 5.2 41.7 1.5 7.4 18.3 2.2 2 0 0 2 2 2 0 AAA domain Apyrase PF06079.11 VBB26071.1 - 5.4e-122 406.6 1.4 6.4e-122 406.4 1.4 1.1 1 0 0 1 1 1 1 Apyrase Ctr PF04145.15 VBB26072.1 - 7.7e-37 127.2 2.1 1.2e-36 126.6 2.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Clathrin PF00637.20 VBB26073.1 - 1.8e-15 57.0 2.5 3.5e-15 56.1 0.1 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 VBB26073.1 - 0.00057 20.3 1.2 0.00057 20.3 1.2 2.6 2 1 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 VBB26073.1 - 0.005 17.1 7.5 0.025 14.9 7.3 2.4 1 1 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.9 VBB26073.1 - 0.0066 16.7 0.4 0.19 12.0 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-rbx1 PF12678.7 VBB26073.1 - 0.0088 16.3 5.6 0.029 14.7 5.6 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 VBB26073.1 - 0.024 14.7 2.8 0.06 13.4 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 VBB26073.1 - 0.048 13.6 4.4 0.18 11.7 4.4 2.1 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 VBB26073.1 - 0.062 14.2 0.3 0.47 11.4 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_5 PF14634.6 VBB26073.1 - 0.33 11.0 6.8 1.1 9.3 6.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 VBB26073.1 - 0.43 10.5 5.0 1.9 8.4 5.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB26073.1 - 1.2 9.2 5.1 3.6 7.7 5.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB26073.1 - 1.6 8.6 6.7 8 6.4 6.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB26073.1 - 2.3 8.1 6.1 7.7 6.5 6.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 VBB26073.1 - 2.5 8.0 7.7 1.2 9.1 2.4 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Chromo PF00385.24 VBB26074.1 - 1.8e-14 53.4 0.4 4e-14 52.3 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 VBB26074.1 - 0.0093 15.8 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RBR PF17208.3 VBB26074.1 - 0.033 14.9 3.7 0.033 14.9 3.7 2.4 2 0 0 2 2 2 0 RNA binding Region Mtf2_C PF14061.6 VBB26074.1 - 0.071 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ECM1 PF05782.11 VBB26074.1 - 0.22 10.4 8.4 10 4.9 7.6 2.1 2 0 0 2 2 2 0 Extracellular matrix protein 1 (ECM1) Rrn6 PF10214.9 VBB26075.1 - 0.014 13.9 11.2 0.015 13.8 11.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Apt1 PF10351.9 VBB26075.1 - 0.019 13.9 11.8 0.019 13.8 11.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 VBB26075.1 - 0.11 11.1 17.4 0.11 11.0 17.4 1.0 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 VBB26075.1 - 0.11 12.3 13.5 0.12 12.2 13.5 1.0 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 VBB26075.1 - 0.22 11.0 1.3 0.22 11.0 1.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec3_C PF09763.9 VBB26075.1 - 0.39 9.1 3.8 0.4 9.0 3.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SSP160 PF06933.11 VBB26075.1 - 0.45 8.7 31.3 0.49 8.5 31.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tmemb_cc2 PF10267.9 VBB26075.1 - 0.49 9.5 4.8 0.51 9.4 4.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peroxin-3 PF04882.12 VBB26075.1 - 0.61 9.0 8.6 0.68 8.9 8.6 1.1 1 0 0 1 1 1 0 Peroxin-3 FAM199X PF15814.5 VBB26075.1 - 0.88 8.6 27.5 1.1 8.2 27.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Herpes_LMP1 PF05297.11 VBB26075.1 - 0.97 8.6 3.8 1.2 8.2 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4614 PF15391.6 VBB26075.1 - 1.9 8.4 22.4 2.4 8.1 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Miga PF10265.9 VBB26075.1 - 2.7 6.8 11.2 2.8 6.8 11.2 1.1 1 0 0 1 1 1 0 Mitoguardin BUD22 PF09073.10 VBB26075.1 - 4.7 6.4 11.9 5.2 6.3 11.9 1.0 1 0 0 1 1 1 0 BUD22 RAWUL PF16207.5 VBB26076.1 - 1.1e-07 32.5 0.0 2.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 VBB26076.1 - 5.1e-06 26.3 8.9 1e-05 25.3 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB26076.1 - 0.0024 17.9 5.7 0.0057 16.7 5.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB26076.1 - 0.003 17.4 11.1 0.0059 16.4 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB26076.1 - 0.011 15.9 8.5 0.026 14.7 8.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 VBB26076.1 - 0.035 14.1 10.3 0.076 13.0 10.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB26076.1 - 0.24 11.3 9.0 0.44 10.4 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 VBB26076.1 - 0.27 11.1 2.1 0.56 10.1 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 VBB26076.1 - 1.5 8.8 5.4 3.2 7.7 5.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF5473 PF17567.2 VBB26076.1 - 9.6 6.5 9.5 0.26 11.6 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Globin PF00042.22 VBB26077.1 - 1.3e-09 38.6 0.0 1e-08 35.7 0.0 1.9 1 1 1 2 2 2 1 Globin DUF5321 PF17254.2 VBB26077.1 - 0.081 12.4 0.3 5.9 6.3 0.0 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5321) Carb_anhydrase PF00194.21 VBB26078.1 - 2e-62 211.0 0.0 2.4e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Beta-prism_lec PF16458.5 VBB26078.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-prism lectin BTB_2 PF02214.22 VBB26079.1 - 2.5e-19 69.4 1.0 1.2e-18 67.3 0.1 2.4 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 VBB26079.1 - 1.2e-14 54.3 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ion_trans PF00520.31 VBB26079.1 - 1.6e-09 37.3 4.0 2.6e-09 36.7 4.0 1.3 1 0 0 1 1 1 1 Ion transport protein Pkinase_Tyr PF07714.17 VBB26079.1 - 0.00077 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB26079.1 - 0.054 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like ThiF PF00899.21 VBB26080.1 - 6.3e-24 84.7 0.0 1.2e-23 83.8 0.0 1.4 1 1 0 1 1 1 1 ThiF family DUF2024 PF09630.10 VBB26080.1 - 0.071 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Patched PF02460.18 VBB26081.1 - 8.4e-149 497.1 32.8 1.2e-127 427.2 19.2 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 VBB26081.1 - 1.2e-37 129.1 4.6 1.2e-37 129.1 4.6 3.1 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 VBB26081.1 - 1.2e-05 23.2 7.2 1.2e-05 23.2 7.2 1.6 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family MMPL PF03176.15 VBB26081.1 - 5.2e-05 22.3 3.0 5.2e-05 22.3 3.0 2.6 3 0 0 3 3 3 1 MMPL family YpmT PF17431.2 VBB26081.1 - 0.12 12.4 1.9 0.79 9.8 1.8 2.6 1 1 0 1 1 1 0 Uncharacterized YmpT-like Pox_H7 PF04787.12 VBB26081.1 - 0.13 12.8 0.4 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 Late protein H7 DUF2644 PF10841.8 VBB26081.1 - 1.7 8.9 5.1 8.1 6.7 5.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Metallophos PF00149.28 VBB26082.1 - 1.8e-31 110.3 0.0 3.3e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_A_exo1 PF01612.20 VBB26082.1 - 0.081 12.6 0.0 0.42 10.3 0.0 2.1 3 0 0 3 3 3 0 3'-5' exonuclease PAX PF00292.18 VBB26083.1 - 5.3e-36 123.3 0.4 7.6e-36 122.8 0.4 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 VBB26083.1 - 8.5e-06 25.4 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 VBB26083.1 - 0.0018 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 VBB26083.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 VBB26083.1 - 0.087 13.4 1.0 1.3 9.7 0.1 2.2 1 1 1 2 2 2 0 Homeodomain-like domain Peptidase_S9 PF00326.21 VBB26085.1 - 9.1e-27 93.9 0.0 3.5e-25 88.7 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 VBB26085.1 - 2.6e-06 27.3 1.2 0.00066 19.4 1.2 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB26085.1 - 0.00044 19.6 0.0 0.075 12.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 VBB26085.1 - 0.00084 19.3 0.0 0.002 18.1 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 VBB26085.1 - 0.0051 16.7 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 VBB26085.1 - 0.01 15.4 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Y_phosphatase PF00102.27 VBB26087.1 - 1.5e-77 260.3 3.4 2.5e-77 259.6 3.4 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 VBB26087.1 - 1.9e-40 136.8 0.1 1.8e-20 72.8 0.0 2.9 3 0 0 3 3 3 2 SH2 domain DSPc PF00782.20 VBB26087.1 - 2.7e-06 27.2 0.1 7.3e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB26087.1 - 0.004 17.3 0.0 0.015 15.4 0.0 1.9 1 1 0 1 1 1 1 Inositol hexakisphosphate SH2_2 PF14633.6 VBB26087.1 - 0.0084 15.5 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 SH2 domain Y_phosphatase3 PF13350.6 VBB26087.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Cbl_N3 PF02762.14 VBB26087.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain 7TM_GPCR_Srw PF10324.9 VBB26089.1 - 6.6e-07 28.9 8.0 0.0001 21.7 1.4 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Importin_rep_5 PF18816.1 VBB26089.1 - 0.087 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Importin repeat PAP2 PF01569.21 VBB26090.1 - 1.2e-16 60.7 7.0 1.2e-16 60.7 7.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily DUF4293 PF14126.6 VBB26090.1 - 2.8 8.2 6.4 0.4 10.9 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Rad17 PF03215.15 VBB26091.1 - 6.9e-21 75.0 1.5 1.2e-18 67.7 1.5 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 VBB26091.1 - 6.1e-08 33.2 0.0 5.3e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB26091.1 - 7.6e-05 23.0 0.0 0.00028 21.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 VBB26091.1 - 0.00074 20.1 0.0 0.0027 18.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 VBB26091.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 VBB26091.1 - 0.0014 19.2 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 VBB26091.1 - 0.0016 18.6 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB26091.1 - 0.0017 18.8 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 VBB26091.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 VBB26091.1 - 0.009 16.4 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase DUF87 PF01935.17 VBB26091.1 - 0.01 16.0 0.2 0.028 14.5 0.0 1.7 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_6 PF12774.7 VBB26091.1 - 0.012 14.6 0.0 0.03 13.3 0.0 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 VBB26091.1 - 0.012 15.6 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 VBB26091.1 - 0.017 15.6 0.3 0.059 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 VBB26091.1 - 0.023 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 VBB26091.1 - 0.024 14.9 0.0 0.11 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA C-terminal domain AAA_PrkA PF08298.11 VBB26091.1 - 0.028 13.3 0.0 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_5 PF07728.14 VBB26091.1 - 0.029 14.4 0.0 0.098 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PINIT PF14324.6 VBB26091.1 - 0.036 14.4 0.2 0.1 13.0 0.1 1.7 2 0 0 2 2 1 0 PINIT domain NTPase_1 PF03266.15 VBB26091.1 - 0.037 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 NTPase Inh PF02974.14 VBB26091.1 - 0.037 14.1 0.3 0.13 12.4 0.1 1.9 2 0 0 2 2 2 0 Protease inhibitor Inh Cytidylate_kin PF02224.18 VBB26091.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_10 PF12846.7 VBB26091.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.6 VBB26091.1 - 0.055 13.9 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 VBB26091.1 - 0.084 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 VBB26091.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 VBB26091.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 VBB26091.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SPK PF04435.18 VBB26091.1 - 0.1 13.1 0.4 0.28 11.6 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF545) dNK PF01712.19 VBB26091.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 VBB26091.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 VBB26091.1 - 0.16 11.7 0.0 0.76 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain CPG4 PF15481.6 VBB26092.1 - 1.9e-06 28.4 16.2 3.7e-06 27.5 11.2 2.7 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 NGP1NT PF08153.12 VBB26093.1 - 6.9e-51 171.8 1.4 1.3e-50 170.9 1.4 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 VBB26093.1 - 7.2e-16 58.3 0.1 3.2e-13 49.7 0.0 3.1 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB26093.1 - 7.9e-06 25.5 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 VBB26093.1 - 9.4e-06 25.6 0.0 2.6e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 VBB26093.1 - 0.0019 17.7 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB26093.1 - 0.0078 15.8 0.0 0.87 9.1 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 VBB26093.1 - 0.083 13.3 0.1 6.4 7.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Muted PF14942.6 VBB26094.1 - 1.3e-06 28.8 5.9 1.7e-06 28.5 5.9 1.1 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein LPD22 PF18834.1 VBB26094.1 - 0.0037 17.4 0.1 0.0077 16.4 0.1 1.5 1 0 0 1 1 1 1 Large polyvalent protein associated domain 22 ACOX PF01756.19 VBB26094.1 - 0.047 13.3 0.2 0.065 12.8 0.2 1.4 1 1 0 1 1 1 0 Acyl-CoA oxidase Sel_put PF04328.13 VBB26094.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Selenoprotein, putative DUF4404 PF14357.6 VBB26094.1 - 0.18 12.5 6.4 2.6 8.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) RIO1 PF01163.22 VBB26095.1 - 1.5e-48 164.9 2.9 3e-48 163.9 0.0 2.6 3 0 0 3 3 3 1 RIO1 family Rio2_N PF09202.11 VBB26095.1 - 4.4e-29 100.5 1.1 2.3e-28 98.2 0.3 2.5 2 0 0 2 2 2 1 Rio2, N-terminal Pribosyltran PF00156.27 VBB26095.1 - 9.5e-21 74.0 0.0 1.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain APH PF01636.23 VBB26095.1 - 5.6e-09 36.3 0.0 0.0019 18.2 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 VBB26095.1 - 4.3e-07 29.5 0.1 1.1e-05 24.9 0.1 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fucokinase PF07959.12 VBB26095.1 - 0.032 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase UPRTase PF14681.6 VBB26095.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFAP1 PF06991.11 VBB26096.1 - 2e-64 217.4 32.1 2e-64 217.4 32.1 4.2 2 2 2 4 4 4 1 Microfibril-associated/Pre-mRNA processing Spt5-NGN PF03439.13 VBB26096.1 - 3.3e-24 84.6 0.2 1e-23 83.0 0.2 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 VBB26096.1 - 1.5e-18 66.0 19.4 5e-07 29.4 0.3 7.3 7 0 0 7 7 7 4 KOW motif CTD PF12815.7 VBB26096.1 - 1.3e-12 48.1 11.5 1.3e-12 48.1 11.5 2.3 2 0 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 VBB26096.1 - 1.4e-11 45.3 15.3 1.4e-11 45.3 15.3 7.4 3 2 3 7 7 7 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 VBB26096.1 - 0.017 15.4 1.2 0.097 12.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Pex19 PF04614.12 VBB26097.1 - 2.2e-32 112.8 12.6 2.8e-32 112.4 12.6 1.1 1 0 0 1 1 1 1 Pex19 protein family IZUMO PF15005.6 VBB26097.1 - 0.11 13.1 6.7 0.12 12.9 2.6 2.3 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF1829 PF08862.10 VBB26097.1 - 0.11 13.0 1.1 0.27 11.8 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1829 DUF3037 PF11236.8 VBB26097.1 - 1.5 9.3 4.3 69 3.9 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) TetR_C_19 PF17924.1 VBB26097.1 - 2.6 8.7 12.0 0.28 11.8 5.4 2.6 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain GlutR_dimer PF00745.20 VBB26097.1 - 3.1 8.3 8.3 1.2 9.7 3.7 2.4 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Hist_deacetyl PF00850.19 VBB26098.1 - 1.9e-82 277.2 0.3 2.4e-82 276.9 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HLH PF00010.26 VBB26099.1 - 4.7e-13 48.9 5.0 1.1e-12 47.8 5.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4578 PF15147.6 VBB26099.1 - 0.072 14.0 0.2 0.22 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) UTP15_C PF09384.10 VBB26100.1 - 5.1e-31 107.3 0.2 7.9e-31 106.7 0.2 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 VBB26100.1 - 2.1e-22 78.9 5.0 0.0036 18.1 0.0 7.1 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB26100.1 - 3.1e-11 43.4 0.0 0.0015 18.8 0.0 5.5 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Phage_pRha PF09669.10 VBB26100.1 - 0.041 14.4 0.6 0.26 11.9 0.1 2.4 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) Ge1_WD40 PF16529.5 VBB26100.1 - 0.11 11.4 0.0 7.6 5.4 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 VBB26101.1 - 3.6e-46 157.1 0.8 7.3e-46 156.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB26101.1 - 8.5e-24 84.0 0.0 4.4e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 VBB26101.1 - 9.3e-16 57.8 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 VBB26101.1 - 6.5e-06 26.3 1.6 1.3e-05 25.3 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 VBB26101.1 - 0.011 15.1 12.4 0.09 12.1 0.0 3.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 VBB26101.1 - 0.75 10.1 3.7 1 9.6 0.0 3.0 4 0 0 4 4 4 0 AAA domain Peptidase_S49_N PF08496.10 VBB26101.1 - 7.3 6.6 7.7 4.8 7.2 3.3 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal ATP-synt_F6 PF05511.11 VBB26102.1 - 1.8e-10 41.1 2.6 9.1e-10 38.8 0.1 2.2 1 1 1 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 MscS_porin PF12795.7 VBB26102.1 - 0.003 17.1 11.1 0.0053 16.3 11.1 1.3 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain Band_7 PF01145.25 VBB26102.1 - 0.0034 17.4 1.7 0.012 15.6 1.7 1.9 1 1 0 1 1 1 1 SPFH domain / Band 7 family ATP_sub_h PF10775.9 VBB26102.1 - 0.048 13.7 0.2 0.048 13.7 0.2 3.2 2 2 1 4 4 4 0 ATP synthase complex subunit h AAA_assoc_C PF09821.9 VBB26102.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.0 2 0 0 2 2 2 0 C-terminal AAA-associated domain AAA_23 PF13476.6 VBB26102.1 - 0.41 11.1 9.6 0.53 10.7 9.6 1.0 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 VBB26102.1 - 0.82 10.2 13.4 1.3 9.6 13.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 VBB26102.1 - 2.2 9.0 10.8 4.9 7.8 5.3 2.3 1 1 1 2 2 2 0 SlyX DUF4446 PF14584.6 VBB26102.1 - 6 6.8 10.7 2.4 8.1 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MLANA PF14991.6 VBB26103.1 - 0.13 12.6 0.3 0.18 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein melan-A Ferrochelatase PF00762.19 VBB26104.1 - 1.3e-89 300.4 0.0 1.5e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 VBB26104.1 - 4.9e-08 33.3 0.0 0.0069 16.7 0.0 2.3 2 0 0 2 2 2 2 CbiX Asp_Arg_Hydrox PF05118.15 VBB26104.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Glyco_transf_64 PF09258.10 VBB26106.1 - 5.7e-83 278.0 0.2 7.8e-83 277.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 VBB26106.1 - 4.3e-21 75.4 0.0 9.7e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 Exostosin family EIF4E-T PF10477.9 VBB26107.1 - 1.6e-19 70.3 35.4 1.1e-13 50.9 18.4 2.9 2 1 1 3 3 3 2 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ribosomal_S3Ae PF01015.18 VBB26108.1 - 5.5e-93 310.2 2.3 7e-93 309.8 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family NLRC4_HD2 PF17776.1 VBB26108.1 - 0.041 14.4 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Abhydro_lipase PF04083.16 VBB26108.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF4024 PF13216.6 VBB26108.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) FH2 PF02181.23 VBB26109.1 - 4.4e-59 200.5 15.5 1.1e-55 189.3 0.7 3.0 2 1 1 3 3 3 2 Formin Homology 2 Domain Med9 PF07544.13 VBB26109.1 - 0.056 13.5 3.8 0.05 13.7 0.5 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Caprin-1_dimer PF18293.1 VBB26111.1 - 0.0012 19.3 0.1 0.0096 16.4 0.1 2.2 1 1 0 1 1 1 1 Caprin-1 dimerization domain UQ_con PF00179.26 VBB26113.1 - 1.7e-35 121.7 0.0 5.5e-19 68.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Galactosyl_T PF01762.21 VBB26113.1 - 1.3e-14 54.5 0.2 2e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase Prok-E2_B PF14461.6 VBB26113.1 - 0.0032 17.2 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic E2 family B DUF1681 PF07933.14 VBB26114.1 - 1.4e-52 177.3 0.0 1.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) RNase_PH PF01138.21 VBB26115.1 - 9.6e-17 61.7 0.1 3e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 VBB26115.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DNA_pol_A_exo1 PF01612.20 VBB26116.1 - 4e-24 85.3 0.8 5.2e-23 81.7 0.8 2.5 1 1 0 1 1 1 1 3'-5' exonuclease Mut7-C PF01927.16 VBB26116.1 - 3.1e-11 43.6 4.8 1.4e-10 41.4 0.1 2.9 3 0 0 3 3 3 1 Mut7-C RNAse domain Xol-1_N PF09108.10 VBB26116.1 - 0.13 12.2 3.1 0.11 12.4 0.3 2.3 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal DNA_pol3_delta PF06144.13 VBB26116.1 - 0.32 10.8 6.8 3.4 7.4 0.4 4.0 4 0 0 4 4 4 0 DNA polymerase III, delta subunit RB_A PF01858.17 VBB26116.1 - 1.5 8.6 9.9 0.52 10.1 0.2 3.7 4 0 0 4 4 4 0 Retinoblastoma-associated protein A domain WD40 PF00400.32 VBB26117.1 - 1.3e-26 92.3 14.1 7.2e-06 26.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB26117.1 - 1.3e-17 63.9 4.8 1.2e-07 31.9 0.4 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB26117.1 - 1.5e-05 25.0 0.0 0.16 11.8 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 VBB26117.1 - 0.014 14.1 0.1 0.024 13.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB26117.1 - 0.036 13.4 0.0 6.4 6.0 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 VBB26117.1 - 0.068 12.1 0.1 0.9 8.4 0.0 2.6 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Alpha-amylase PF00128.24 VBB26119.1 - 2.3e-42 145.8 3.1 2.3e-42 145.8 3.1 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 VBB26119.1 - 2e-19 68.9 3.1 5.3e-19 67.5 3.1 1.7 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus YjcZ PF13990.6 VBB26119.1 - 0.044 13.2 0.2 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 YjcZ-like protein DUF2155 PF09923.9 VBB26120.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) Ribosomal_L44 PF00935.19 VBB26121.1 - 4.3e-35 120.0 14.9 6.2e-35 119.5 14.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Yop-YscD_cpl PF16697.5 VBB26122.1 - 2.3e-05 24.6 0.0 0.00012 22.4 0.0 2.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Adeno_E3B PF03376.14 VBB26123.1 - 0.066 13.5 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3B protein ELM2 PF01448.24 VBB26124.1 - 1.4e-06 28.9 1.5 3.3e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 ELM2 domain SMC_N PF02463.19 VBB26126.1 - 2.6e-17 63.0 8.7 1e-16 61.0 8.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 VBB26126.1 - 4.4e-11 43.7 27.3 4.4e-11 43.7 27.3 5.4 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 VBB26126.1 - 3.2e-06 27.2 8.0 0.0022 17.9 0.1 3.4 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 VBB26126.1 - 0.0055 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 VBB26126.1 - 0.054 14.0 0.0 0.054 14.0 0.0 4.8 4 2 0 4 4 4 0 ABC transporter DUF1394 PF07159.12 VBB26127.1 - 1.6e-110 369.1 0.0 1.8e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) F-box-like PF12937.7 VBB26127.1 - 0.14 12.1 0.7 2 8.4 0.1 2.8 3 0 0 3 3 3 0 F-box-like Filament PF00038.21 VBB26128.1 - 7.2e-66 222.9 44.7 8.7e-64 216.0 44.7 2.2 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 VBB26128.1 - 1.3e-10 41.6 0.0 2.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain ATG16 PF08614.11 VBB26128.1 - 0.00055 20.2 43.7 0.015 15.5 8.2 4.6 1 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 VBB26128.1 - 0.0014 16.6 46.4 0.0039 15.1 45.8 2.2 1 1 0 1 1 1 1 Myosin tail TPR_MLP1_2 PF07926.12 VBB26128.1 - 0.0026 17.8 37.9 0.34 11.0 6.9 5.2 1 1 4 6 6 6 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 VBB26128.1 - 0.0029 17.6 2.0 0.0029 17.6 2.0 4.6 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 VBB26128.1 - 0.0031 18.0 49.9 0.32 11.5 7.6 4.9 1 1 3 4 4 4 2 Apg6 coiled-coil region YabA PF06156.13 VBB26128.1 - 0.0062 17.2 34.5 0.48 11.1 3.3 5.9 3 2 4 7 7 6 3 Initiation control protein YabA Bacillus_HBL PF05791.11 VBB26128.1 - 0.021 14.7 18.1 0.38 10.6 3.0 4.1 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 VBB26128.1 - 0.022 13.6 37.9 0.032 13.1 6.2 3.6 1 1 3 4 4 4 0 Spc7 kinetochore protein SNCAIP_SNCA_bd PF16700.5 VBB26128.1 - 0.026 14.2 0.5 0.026 14.2 0.5 2.8 4 0 0 4 4 2 0 Synphilin-1 alpha-Synuclein-binding domain Lectin_N PF03954.14 VBB26128.1 - 0.035 13.8 8.3 7.6 6.3 0.1 4.3 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF447 PF04289.12 VBB26128.1 - 0.049 13.4 0.2 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF447) Prominin PF05478.11 VBB26128.1 - 0.098 10.6 17.6 0.0055 14.7 7.3 2.8 1 1 2 3 3 3 0 Prominin Laminin_II PF06009.12 VBB26128.1 - 0.18 11.8 22.4 0.35 10.9 0.9 4.8 2 2 2 4 4 4 0 Laminin Domain II Atg14 PF10186.9 VBB26128.1 - 0.23 10.5 29.9 1.1 8.3 1.3 3.4 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 VBB26128.1 - 1.3 9.3 33.7 0.064 13.5 1.5 5.5 4 2 1 5 5 5 0 ABC transporter C-terminal domain FUSC PF04632.12 VBB26128.1 - 1.4 7.4 24.3 1.6 7.2 7.1 3.1 2 1 1 3 3 3 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 VBB26128.1 - 1.7 9.4 17.9 3.5 8.4 1.1 4.7 2 1 3 5 5 5 0 Occludin homology domain THP2 PF09432.10 VBB26128.1 - 2 8.5 13.1 5.1 7.2 0.0 4.3 3 2 1 4 4 4 0 Tho complex subunit THP2 Fzo_mitofusin PF04799.13 VBB26128.1 - 2 7.9 18.4 0.11 12.0 0.2 4.2 1 1 3 5 5 5 0 fzo-like conserved region UPF0242 PF06785.11 VBB26128.1 - 2.5 8.2 35.9 0.6 10.2 7.5 3.8 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 VBB26128.1 - 2.7 7.8 39.8 2.1 8.1 2.3 6.9 4 2 3 7 7 7 0 Septum formation initiator KASH_CCD PF14662.6 VBB26128.1 - 3.3 7.5 38.1 0.027 14.3 9.0 4.1 2 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 VBB26128.1 - 5.8 6.6 36.4 0.06 13.1 4.7 4.8 2 2 1 4 4 4 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.9 VBB26128.1 - 7 7.0 21.3 2.5 8.5 0.5 5.4 4 2 1 6 6 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc42p PF11544.8 VBB26128.1 - 7.2 6.7 15.8 0.27 11.3 2.4 4.0 3 0 0 3 3 3 0 Spindle pole body component Spc42p Golgin_A5 PF09787.9 VBB26128.1 - 8.1 5.8 46.7 0.19 11.2 10.7 4.0 1 1 5 6 6 6 0 Golgin subfamily A member 5 Fez1 PF06818.15 VBB26128.1 - 10 6.5 42.1 1.6 9.1 6.0 4.0 1 1 2 3 3 2 0 Fez1 EGF_2 PF07974.13 VBB26129.1 - 6.3e-07 29.7 43.5 0.042 14.2 4.1 5.6 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 VBB26129.1 - 1.7e-06 28.0 43.9 0.026 14.7 4.9 5.3 1 1 4 5 5 5 5 Laminin EGF domain EGF PF00008.27 VBB26129.1 - 0.00072 19.8 31.2 0.084 13.2 2.0 6.6 5 3 0 5 5 5 4 EGF-like domain I-EGF_1 PF18372.1 VBB26129.1 - 0.038 14.1 0.8 0.038 14.1 0.8 4.8 5 0 0 5 5 5 0 Integrin beta epidermal growth factor like domain 1 CTV_P6 PF06706.11 VBB26129.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein EB PF01683.18 VBB26129.1 - 3.5 8.0 38.4 18 5.7 7.7 5.0 1 1 3 4 4 4 0 EB module AA_permease PF00324.21 VBB26130.1 - 1.3e-46 159.2 42.2 7.7e-40 136.9 32.5 2.5 1 1 1 2 2 2 2 Amino acid permease SLC12 PF03522.15 VBB26130.1 - 6.6e-26 91.3 4.2 6.2e-12 45.3 0.0 3.5 3 1 1 4 4 4 3 Solute carrier family 12 AA_permease_2 PF13520.6 VBB26130.1 - 1.6e-07 30.5 38.0 1.6e-07 30.5 38.0 1.9 1 1 0 2 2 2 1 Amino acid permease Filamin PF00630.19 VBB26131.1 - 1.1e-12 48.7 0.1 2.4e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat NHL PF01436.21 VBB26131.1 - 4.3e-08 32.8 4.5 0.015 15.3 0.0 4.8 5 0 0 5 5 5 2 NHL repeat zf-RING_UBOX PF13445.6 VBB26131.1 - 0.0055 16.7 4.3 0.0055 16.7 4.3 3.7 4 0 0 4 4 4 1 RING-type zinc-finger zf-B_box PF00643.24 VBB26131.1 - 0.0058 16.7 7.8 0.0058 16.7 7.8 4.2 5 0 0 5 5 5 1 B-box zinc finger zf-RING_5 PF14634.6 VBB26131.1 - 0.014 15.3 10.4 0.014 15.3 10.4 4.3 4 1 0 4 4 4 0 zinc-RING finger domain Invasin_D3 PF09134.10 VBB26131.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Invasin, domain 3 DUF3500 PF12006.8 VBB26131.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) IBR PF01485.21 VBB26131.1 - 6.4 7.1 14.6 1.7 8.9 3.8 3.2 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain ERG2_Sigma1R PF04622.12 VBB26132.1 - 7.3e-22 77.7 0.0 9.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein TPK_catalytic PF04263.16 VBB26133.1 - 4.3e-32 110.7 0.0 6.1e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 VBB26133.1 - 5.8e-15 54.8 0.2 9.9e-15 54.0 0.2 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NUC173 PF08161.12 VBB26134.1 - 2.5e-43 148.1 4.6 8.7e-43 146.4 0.6 2.9 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.22 VBB26134.1 - 4.9 7.7 9.8 0.96 9.9 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat DUF1768 PF08719.11 VBB26135.1 - 2.9e-14 53.6 0.0 5.1e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Prok-RING_4 PF14447.6 VBB26136.1 - 0.018 14.9 2.3 0.051 13.4 2.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4428 PF14471.6 VBB26136.1 - 0.03 14.3 2.4 0.081 12.9 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Inositol_P PF00459.25 VBB26137.1 - 8.6e-57 192.7 0.1 9.7e-57 192.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Tctex-1 PF03645.13 VBB26138.1 - 3.6e-24 85.0 3.3 4.1e-24 84.8 3.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Vinculin PF01044.19 VBB26140.1 - 1.6e-65 222.0 10.4 3.2e-40 138.2 2.7 3.2 2 1 1 3 3 3 3 Vinculin family CHASE3 PF05227.13 VBB26140.1 - 0.052 13.5 0.1 2.3 8.1 0.0 2.9 2 0 0 2 2 2 0 CHASE3 domain Ssu72 PF04722.13 VBB26140.1 - 0.058 13.0 0.1 0.21 11.1 0.1 1.9 1 0 0 1 1 1 0 Ssu72-like protein TBCC_N PF16752.5 VBB26140.1 - 0.46 10.9 5.1 13 6.2 0.0 3.9 4 1 0 5 5 5 0 Tubulin-specific chaperone C N-terminal domain GIT1_C PF12205.8 VBB26140.1 - 4.5 7.4 6.2 11 6.1 0.1 4.0 4 1 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term Laminin_EGF PF00053.24 VBB26141.1 - 1.8e-33 114.4 309.6 2.3e-05 24.4 16.3 17.1 8 4 9 17 17 17 13 Laminin EGF domain hEGF PF12661.7 VBB26141.1 - 0.00096 19.7 36.1 0.0028 18.2 5.9 21.3 20 5 3 23 23 23 10 Human growth factor-like EGF DSL PF01414.19 VBB26141.1 - 0.0011 19.2 13.7 0.0011 19.2 13.7 16.3 15 1 1 16 16 16 4 Delta serrate ligand EGF_2 PF07974.13 VBB26141.1 - 0.0037 17.6 16.7 0.0037 17.6 16.7 24.9 19 8 1 20 20 20 10 EGF-like domain DUF5453 PF17534.2 VBB26141.1 - 0.028 14.4 0.4 0.042 13.8 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Claudin_3 PF06653.11 VBB26141.1 - 0.13 12.2 0.3 0.23 11.4 0.3 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like BatA PF07584.11 VBB26141.1 - 0.2 12.0 0.1 0.31 11.4 0.1 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal EMI PF07546.13 VBB26142.1 - 0.00011 22.9 4.2 0.00011 22.9 4.2 2.9 3 1 0 3 3 3 1 EMI domain Ras PF00071.22 VBB26143.1 - 2.5e-51 173.5 0.0 3.4e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB26143.1 - 1.2e-30 106.1 0.1 4.9e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB26143.1 - 2e-16 59.9 0.0 2.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB26143.1 - 2.3e-05 24.4 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 VBB26143.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 VBB26143.1 - 0.00062 19.4 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 VBB26143.1 - 0.0019 17.6 0.1 0.0054 16.1 0.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 VBB26143.1 - 0.042 13.6 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 VBB26143.1 - 0.044 13.5 0.4 0.58 9.9 0.4 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 VBB26143.1 - 0.07 12.8 0.1 2.1 7.9 0.0 2.6 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Thioredoxin_14 PF18402.1 VBB26143.1 - 0.08 12.9 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain ABC_tran PF00005.27 VBB26143.1 - 0.21 12.1 0.7 0.84 10.1 0.0 2.0 2 1 0 2 2 2 0 ABC transporter ERO1 PF04137.15 VBB26144.1 - 4.6e-112 374.7 0.1 5.7e-112 374.4 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RNase_Zc3h12a PF11977.8 VBB26145.1 - 5.4e-59 198.4 0.0 9.4e-59 197.7 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 VBB26145.1 - 2.9e-10 39.9 0.3 6.3e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain Regnase_1_C PF18561.1 VBB26145.1 - 8.6e-06 25.4 0.2 2.6e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 VBB26145.1 - 2.5e-05 23.9 6.2 5.3e-05 22.9 6.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 VBB26145.1 - 0.0087 15.9 2.6 0.021 14.7 2.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 VBB26145.1 - 0.036 14.8 0.2 0.079 13.7 0.2 1.5 1 0 0 1 1 1 0 Torus domain PRORP PF16953.5 VBB26145.1 - 0.037 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 VBB26145.1 - 1.2 9.7 3.6 3.3 8.3 3.6 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 VBB26145.1 - 2.3 8.4 5.3 5.4 7.2 5.3 1.7 1 0 0 1 1 1 0 Zinc finger domain adh_short PF00106.25 VBB26146.1 - 8.5e-30 103.7 0.2 2.5e-29 102.2 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB26146.1 - 2.1e-25 89.7 0.1 7.1e-25 87.9 0.2 1.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB26146.1 - 1.7e-12 47.6 0.0 3.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 KR domain rRNA_methylase PF06962.12 VBB26146.1 - 0.044 13.8 0.5 0.52 10.3 0.0 2.6 3 0 0 3 3 3 0 Putative rRNA methylase CSN8_PSD8_EIF3K PF10075.9 VBB26147.1 - 1.4e-30 106.2 0.1 4.3e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Ion_trans_2 PF07885.16 VBB26148.1 - 3.9e-19 68.4 23.1 1.5e-15 56.9 5.1 4.2 3 1 1 4 4 4 3 Ion channel Ion_trans PF00520.31 VBB26148.1 - 3.5e-05 23.1 4.4 0.00011 21.5 0.5 2.2 2 0 0 2 2 2 1 Ion transport protein DUF2254 PF10011.9 VBB26148.1 - 0.00053 18.9 1.4 0.0013 17.6 1.4 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) IRK PF01007.20 VBB26148.1 - 0.0013 18.6 0.2 0.0013 18.6 0.2 1.9 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain Ctr PF04145.15 VBB26148.1 - 6.2 7.4 8.2 1.5 9.4 0.7 2.6 1 1 1 2 2 2 0 Ctr copper transporter family DNA_primase_S PF01896.19 VBB26150.1 - 9.4e-47 159.3 0.1 1.3e-46 158.9 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit MADF_DNA_bdg PF10545.9 VBB26150.1 - 0.00076 19.7 0.9 0.0015 18.8 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Ion_trans_2 PF07885.16 VBB26151.1 - 4.4e-35 119.5 25.2 7.4e-18 64.3 4.3 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB26151.1 - 1.5e-14 53.9 2.9 6.5e-09 35.4 0.2 2.4 1 1 1 2 2 2 2 Ion transport protein IRK PF01007.20 VBB26151.1 - 0.00026 20.8 1.7 0.54 10.1 0.1 2.6 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain GAIN PF16489.5 VBB26151.1 - 0.014 14.8 0.1 0.23 10.8 0.1 2.3 2 0 0 2 2 2 0 GPCR-Autoproteolysis INducing (GAIN) domain Maf PF02545.14 VBB26151.1 - 0.034 14.0 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Maf-like protein DUF1768 PF08719.11 VBB26152.1 - 4.2e-27 95.4 0.0 2.3e-09 37.7 0.0 3.9 3 1 0 3 3 3 3 Domain of unknown function (DUF1768) SnoaL_3 PF13474.6 VBB26152.1 - 0.01 16.1 0.1 0.036 14.3 0.1 1.9 2 0 0 2 2 2 0 SnoaL-like domain DUF2457 PF10446.9 VBB26152.1 - 0.68 9.0 9.5 1.1 8.3 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Microcephalin PF12258.8 VBB26152.1 - 4.6 6.4 7.3 7 5.8 7.3 1.2 1 0 0 1 1 1 0 Microcephalin protein FAM76 PF16046.5 VBB26153.1 - 0.049 13.0 9.2 0.065 12.6 9.2 1.2 1 0 0 1 1 1 0 FAM76 protein FlxA PF14282.6 VBB26153.1 - 1.2 9.2 8.4 0.13 12.3 2.1 2.2 2 0 0 2 2 2 0 FlxA-like protein TAFII55_N PF04658.13 VBB26154.1 - 8.3e-56 188.1 3.2 1.1e-55 187.8 3.2 1.1 1 0 0 1 1 1 1 TAFII55 protein conserved region Exotox-A_cataly PF09009.10 VBB26154.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic Sulfotransfer_3 PF13469.6 VBB26155.1 - 3.1e-51 174.8 0.0 5e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 VBB26155.1 - 7.7e-07 28.9 0.1 4.8e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Rad51 PF08423.11 VBB26156.1 - 5.2e-109 363.4 0.1 6.8e-109 363.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 VBB26156.1 - 9e-11 41.7 0.1 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 VBB26156.1 - 2.4e-08 33.6 0.2 4.2e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 VBB26156.1 - 2.3e-07 30.6 0.0 3.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 VBB26156.1 - 0.00012 22.7 0.9 0.00026 21.5 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_24 PF13479.6 VBB26156.1 - 0.0035 17.1 0.1 0.007 16.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 VBB26156.1 - 0.0048 16.3 0.5 0.061 12.7 0.5 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 VBB26156.1 - 0.045 12.9 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein Metallophos PF00149.28 VBB26157.1 - 9.3e-41 140.6 0.6 1.2e-40 140.3 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB26157.1 - 2e-13 50.6 0.0 3.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF3173 PF11372.8 VBB26157.1 - 0.22 11.4 0.0 0.66 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Metallophos PF00149.28 VBB26158.1 - 9.3e-41 140.6 0.6 1.2e-40 140.3 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB26158.1 - 2e-13 50.6 0.0 3.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF3173 PF11372.8 VBB26158.1 - 0.22 11.4 0.0 0.66 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) WD40 PF00400.32 VBB26159.1 - 3.5e-09 37.1 3.1 0.00038 21.2 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Cnn_1N PF07989.11 VBB26159.1 - 0.048 13.8 0.1 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 VBB26159.1 - 0.088 13.0 1.2 0.16 12.2 1.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 VBB26159.1 - 2.2 8.4 4.3 0.69 10.0 1.4 1.6 2 0 0 2 2 2 0 Basic region leucine zipper SpoIIE PF07228.12 VBB26160.1 - 2.3e-14 53.8 0.0 3.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 VBB26160.1 - 2e-10 40.8 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 VBB26160.1 - 5.1e-05 23.0 0.0 0.0007 19.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Fer4 PF00037.27 VBB26161.1 - 1.4e-14 53.2 17.3 5.4e-09 35.5 4.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 VBB26161.1 - 1.1e-13 51.5 10.1 2e-13 50.7 10.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 VBB26161.1 - 4.7e-11 43.5 5.5 2e-05 25.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 VBB26161.1 - 9.5e-10 38.5 33.5 3.2e-06 27.2 13.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 VBB26161.1 - 2.4e-09 37.2 21.8 1.4e-06 28.3 12.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 VBB26161.1 - 9.6e-09 35.3 10.2 1.9e-08 34.3 10.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 VBB26161.1 - 1.6e-07 31.6 19.9 3.5e-05 24.2 11.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 VBB26161.1 - 2e-07 30.8 17.7 0.00037 20.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 VBB26161.1 - 8.6e-07 28.7 12.1 0.0021 18.1 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 VBB26161.1 - 5.1e-06 26.6 10.9 0.00032 21.0 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 VBB26161.1 - 6.2e-05 23.5 11.4 0.0024 18.4 12.2 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 VBB26161.1 - 0.0047 17.4 14.8 0.22 12.1 2.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 VBB26161.1 - 0.0063 17.4 16.5 0.014 16.3 4.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 VBB26161.1 - 0.0099 16.1 5.2 0.56 10.5 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 VBB26161.1 - 0.053 13.7 9.1 8.5 6.6 9.4 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 VBB26161.1 - 0.27 11.4 5.9 1.3 9.2 0.7 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 VBB26161.1 - 0.54 11.1 11.6 2 9.3 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Integrin_beta PF00362.18 VBB26163.1 - 3.5e-106 354.4 0.0 5.1e-106 353.9 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 VBB26163.1 - 1.4e-17 64.0 5.5 1.4e-17 64.0 5.5 4.6 5 1 1 6 6 6 1 Integrin beta tail domain PSI_integrin PF17205.3 VBB26163.1 - 1.3e-10 40.8 8.8 1.3e-10 40.8 8.8 4.0 3 1 0 3 3 3 1 Integrin plexin domain I-EGF_1 PF18372.1 VBB26163.1 - 2.1e-10 40.5 69.0 2.8e-05 24.1 10.0 5.8 5 0 0 5 5 5 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 VBB26163.1 - 2.3e-07 31.1 90.9 3.9e-06 27.1 15.4 6.5 5 2 1 6 6 6 3 EGF-like domain Integrin_b_cyt PF08725.11 VBB26163.1 - 3.2e-06 26.7 0.0 8.5e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain SNF2_N PF00176.23 VBB26165.1 - 3.3e-65 220.1 1.3 6.8e-65 219.1 1.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB26165.1 - 1.5e-16 60.7 0.0 4.4e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 VBB26165.1 - 3.2e-14 53.0 12.6 1.9e-13 50.5 8.8 3.1 1 1 1 2 2 2 1 HSA ResIII PF04851.15 VBB26165.1 - 7.6e-07 29.3 0.2 4.4e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2683 PF10884.8 VBB26165.1 - 0.077 13.3 1.6 0.42 10.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) DUF1798 PF08807.10 VBB26165.1 - 1.1 9.5 5.8 0.66 10.1 1.9 2.7 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Laminin_II PF06009.12 VBB26165.1 - 1.7 8.6 8.7 0.43 10.6 2.3 3.1 3 0 0 3 3 3 0 Laminin Domain II zf-C2H2_4 PF13894.6 VBB26166.1 - 1.2e-06 28.9 11.6 0.0014 19.2 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 VBB26166.1 - 8e-06 26.1 3.5 0.0058 16.8 0.3 3.3 3 0 0 3 3 3 1 Aberrant zinc-finger zf-C2H2 PF00096.26 VBB26166.1 - 0.00012 22.3 12.2 0.049 14.1 1.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 VBB26166.1 - 0.0009 19.2 0.8 0.0009 19.2 0.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB26166.1 - 0.015 15.7 6.3 0.44 11.1 1.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf_ZIC PF18366.1 VBB26166.1 - 0.045 13.8 2.7 4.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 VBB26166.1 - 0.064 13.6 0.6 1.6 9.1 0.0 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 VBB26166.1 - 0.075 13.3 1.7 17 5.8 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 VBB26166.1 - 0.13 12.9 1.0 5.6 7.7 0.0 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2HE PF16278.5 VBB26166.1 - 0.46 11.0 2.3 0.57 10.7 0.1 2.4 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 VBB26166.1 - 1.3 7.5 4.5 1.2 7.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF629) DUF4698 PF15769.5 VBB26166.1 - 2.7 6.9 4.8 4.1 6.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) ERCC3_RAD25_C PF16203.5 VBB26167.1 - 1.2e-113 378.4 3.0 2e-113 377.7 3.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 VBB26167.1 - 1.3e-36 125.6 0.0 2.6e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB26167.1 - 3.3e-17 63.0 0.0 9.2e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 VBB26167.1 - 5.2e-11 42.9 0.2 1.5e-10 41.4 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 VBB26167.1 - 0.0023 16.7 0.0 0.0055 15.5 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain MMR_HSR1 PF01926.23 VBB26168.1 - 1.6e-21 76.5 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 VBB26168.1 - 2e-19 69.7 1.3 7.2e-19 67.9 1.3 1.8 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 VBB26168.1 - 3.2e-06 26.8 0.0 1.1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 VBB26168.1 - 0.013 15.1 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 VBB26168.1 - 0.014 15.4 0.0 2.4 8.2 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 VBB26168.1 - 0.018 14.5 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 VBB26168.1 - 0.057 12.4 0.1 0.53 9.2 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 VBB26168.1 - 0.065 13.1 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 VBB26168.1 - 0.075 12.6 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UCH_1 PF13423.6 VBB26169.1 - 2.1e-22 80.2 7.8 3.3e-22 79.5 7.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CCCH_2 PF14608.6 VBB26169.1 - 0.00035 20.9 2.3 0.00095 19.6 2.3 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger ANAPC4_WD40 PF12894.7 VBB26169.1 - 0.012 15.9 0.0 0.28 11.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TIP120 PF08623.10 VBB26169.1 - 0.034 13.9 0.1 5 6.9 0.0 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) eIF2A PF08662.11 VBB26169.1 - 0.12 12.3 0.1 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A UCH PF00443.29 VBB26169.1 - 0.15 11.6 4.5 0.19 11.2 2.2 2.3 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Pkinase_Tyr PF07714.17 VBB26170.1 - 3.9e-34 118.1 0.0 6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 VBB26170.1 - 4.6e-29 100.8 5.1 1.1e-15 58.0 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Pkinase PF00069.25 VBB26170.1 - 8.2e-20 71.3 0.0 1.7e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 VBB26170.1 - 1.5e-19 69.8 7.1 3.3e-09 36.8 1.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 VBB26170.1 - 1.9e-19 69.7 1.4 3e-09 37.2 0.2 4.1 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB26170.1 - 3.5e-17 62.0 0.6 4.9e-06 26.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 VBB26170.1 - 2e-14 52.3 1.1 0.0019 18.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat CDC50 PF03381.15 VBB26171.1 - 2.6e-57 194.5 0.3 3.3e-57 194.2 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Gar1 PF04410.14 VBB26172.1 - 4e-35 120.9 0.0 5.1e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region V-ATPase_C PF03223.15 VBB26173.1 - 2.2e-149 497.9 4.1 2.7e-149 497.6 4.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit C Peptidase_C78 PF07910.13 VBB26173.1 - 6e-37 127.2 4.1 6.6e-35 120.5 4.1 2.4 1 1 0 1 1 1 1 Peptidase family C78 Baculo_PEP_C PF04513.12 VBB26173.1 - 0.037 14.0 3.0 0.053 13.6 1.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C54 PF03416.19 VBB26173.1 - 0.15 11.5 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C54 BicD PF09730.9 VBB26174.1 - 8.7e-86 288.9 69.8 2.9e-45 155.0 37.4 3.4 2 1 1 3 3 3 3 Microtubule-associated protein Bicaudal-D Bacillus_HBL PF05791.11 VBB26174.1 - 0.032 14.1 0.8 0.032 14.1 0.8 5.5 3 2 2 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) An_peroxidase PF03098.15 VBB26176.1 - 8.7e-187 621.9 0.0 2.4e-186 620.4 0.0 1.7 2 0 0 2 2 2 1 Animal haem peroxidase I-set PF07679.16 VBB26176.1 - 5.1e-33 113.0 0.0 7.9e-17 61.1 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB26176.1 - 2.3e-30 105.0 0.1 1.3e-16 60.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB26176.1 - 1.7e-23 82.6 0.2 2.2e-13 50.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 VBB26176.1 - 3e-20 72.3 0.2 2.3e-10 40.6 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 VBB26176.1 - 4.5e-08 33.2 0.6 0.065 13.4 0.1 3.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB26176.1 - 0.0032 17.5 0.0 0.035 14.2 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB26176.1 - 0.0058 16.2 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain VWC PF00093.18 VBB26176.1 - 0.009 16.3 10.2 0.009 16.3 10.2 2.8 4 0 0 4 4 4 1 von Willebrand factor type C domain Ig_C17orf99 PF17736.1 VBB26176.1 - 0.083 12.9 0.0 29 4.8 0.0 3.0 2 1 0 2 2 2 0 C17orf99 Ig domain JmjC PF02373.22 VBB26177.1 - 0.031 14.7 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF3537 PF12056.8 VBB26177.1 - 1.2 7.8 4.0 11 4.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) NAP PF00956.18 VBB26178.1 - 1.1e-29 103.5 13.2 2.5e-24 85.9 5.2 2.9 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 VBB26178.1 - 0.011 15.6 1.2 0.024 14.6 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein EzrA PF06160.12 VBB26178.1 - 0.013 13.7 0.4 0.019 13.2 0.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Nore1-SARAH PF16517.5 VBB26178.1 - 0.03 14.2 1.3 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF4407 PF14362.6 VBB26178.1 - 0.043 13.2 0.2 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAS-6_N PF16531.5 VBB26178.1 - 0.048 14.3 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal DUF5082 PF16888.5 VBB26178.1 - 0.08 13.2 2.8 0.15 12.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Cytochrom_B562 PF07361.11 VBB26178.1 - 0.089 13.5 0.3 0.19 12.4 0.3 1.5 1 0 0 1 1 1 0 Cytochrome b562 Pup PF05639.11 VBB26178.1 - 0.15 13.0 0.6 0.15 13.0 0.6 2.7 2 0 0 2 2 2 0 Pup-like protein MscS_porin PF12795.7 VBB26179.1 - 0.00095 18.8 14.3 0.0012 18.5 7.1 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain NYD-SP28 PF14772.6 VBB26179.1 - 0.0064 16.5 1.5 0.0064 16.5 1.5 2.7 2 1 1 3 3 3 1 Sperm tail Filament PF00038.21 VBB26179.1 - 0.022 14.3 17.3 0.048 13.2 17.3 1.5 1 0 0 1 1 1 0 Intermediate filament protein Csm1_N PF18504.1 VBB26179.1 - 0.14 12.5 18.3 1.3 9.4 4.6 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain LMBR1 PF04791.16 VBB26179.1 - 0.6 8.9 7.2 0.82 8.5 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SpoOE-like PF09388.10 VBB26179.1 - 1.5 8.8 12.3 3.1 7.8 1.7 2.8 2 1 0 2 2 2 0 Spo0E like sporulation regulatory protein KxDL PF10241.9 VBB26179.1 - 1.5 9.1 8.1 0.54 10.6 0.5 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 VBB26179.1 - 1.8 7.8 13.8 2.7 7.3 13.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SPATA1_C PF15743.5 VBB26179.1 - 2.3 8.3 15.3 0.42 10.7 9.7 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Cadherin_4 PF17803.1 VBB26179.1 - 2.4 8.8 6.0 4.3 8.0 4.6 2.2 1 1 1 2 2 2 0 Bacterial cadherin-like domain Spc7 PF08317.11 VBB26179.1 - 2.9 6.7 21.8 0.12 11.3 11.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Cauli_AT PF03233.13 VBB26179.1 - 3.3 7.6 8.3 0.32 10.9 2.3 2.2 1 1 0 2 2 2 0 Aphid transmission protein DUF883 PF05957.13 VBB26179.1 - 9.2 6.9 7.6 28 5.4 3.9 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF775 PF05603.12 VBB26180.1 - 2e-43 148.3 0.2 2.8e-43 147.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Collagen PF01391.18 VBB26181.1 - 4.7e-22 77.5 106.3 0.00023 20.8 7.2 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26181.1 - 5.2e-16 58.4 1.1 6.9e-16 58.1 1.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain MCH PF02289.16 VBB26181.1 - 0.24 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Tfb2 PF03849.14 VBB26182.1 - 5.7e-87 292.0 0.3 6.9e-86 288.4 0.3 2.0 1 1 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 VBB26182.1 - 8.1e-15 55.0 2.2 7.2e-14 52.0 0.8 2.9 2 1 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 VBB26182.1 - 0.0072 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cry1Ac_D5 PF17997.1 VBB26182.1 - 0.048 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 TPR_12 PF13424.6 VBB26184.1 - 2.8e-08 33.9 0.0 8.6e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB26184.1 - 0.00015 21.6 0.3 2 8.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB26184.1 - 0.0032 17.5 0.1 4.4 7.8 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat HemY_N PF07219.13 VBB26184.1 - 0.0072 16.5 0.2 0.48 10.6 0.0 2.4 2 0 0 2 2 2 1 HemY protein N-terminus TolA_bind_tri PF16331.5 VBB26184.1 - 0.043 13.9 1.8 0.1 12.7 1.8 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation TPR_1 PF00515.28 VBB26184.1 - 0.11 12.3 1.4 3.8 7.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DB PF01682.19 VBB26185.1 - 3.1e-13 49.9 12.2 3.1e-13 49.9 12.2 2.1 1 1 1 2 2 2 2 DB module Ank_2 PF12796.7 VBB26186.1 - 1.8e-24 86.1 4.5 7.3e-11 42.5 0.8 3.4 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB26186.1 - 9.5e-20 70.7 4.3 7.1e-10 39.2 0.7 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB26186.1 - 5.3e-19 68.0 5.4 3.4e-08 33.6 0.2 4.5 2 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 VBB26186.1 - 1.8e-16 59.7 7.3 6.5e-07 29.5 0.2 5.9 5 1 0 5 5 5 4 Ankyrin repeat SAM_1 PF00536.30 VBB26186.1 - 6.8e-13 48.9 1.0 1.6e-12 47.6 0.3 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB26186.1 - 6.9e-13 48.5 0.2 1.8e-12 47.2 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 VBB26186.1 - 7.8e-13 47.4 3.5 0.0067 16.9 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat PDZ_6 PF17820.1 VBB26186.1 - 2.1e-11 43.5 0.1 4.2e-10 39.3 0.0 2.9 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 VBB26186.1 - 9.7e-08 32.3 0.1 4.5e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB26186.1 - 0.0012 19.2 0.1 0.0031 17.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SAM_PNT PF02198.16 VBB26186.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 VBB26186.1 - 0.04 13.7 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Serum_albumin PF00273.20 VBB26186.1 - 0.045 13.5 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Serum albumin family Macoilin PF09726.9 VBB26186.1 - 0.7 8.4 4.1 1.2 7.6 4.1 1.3 1 0 0 1 1 1 0 Macoilin family PID PF00640.23 VBB26187.1 - 3.8e-11 43.2 0.4 7.4e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 VBB26187.1 - 0.00068 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 VBB26187.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Adeno_shaft PF00608.17 VBB26187.1 - 0.0022 17.7 0.1 0.0052 16.5 0.1 1.7 1 0 0 1 1 1 1 Adenoviral fibre protein (repeat/shaft region) Spermine_synth PF01564.17 VBB26188.1 - 2.3e-64 216.3 0.0 3.3e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 VBB26188.1 - 4.2e-19 68.2 0.2 2.4e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 VBB26188.1 - 9.4e-05 23.0 0.0 0.00019 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 VBB26188.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 VBB26188.1 - 0.021 15.6 0.0 0.085 13.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 VBB26188.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain ING PF12998.7 VBB26189.1 - 3.7e-14 53.1 1.0 3.7e-14 53.1 1.0 1.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 VBB26189.1 - 1.3e-05 25.0 8.5 2.3e-05 24.2 8.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 VBB26189.1 - 0.017 15.3 2.6 0.034 14.4 2.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF5354 PF17305.2 VBB26189.1 - 0.12 12.6 0.4 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5354) NDUF_B8 PF05821.11 VBB26190.1 - 3.6e-38 131.2 9.9 4e-38 131.0 9.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) LIM_bind PF01803.16 VBB26194.1 - 5.7e-30 104.6 12.2 2.6e-29 102.4 4.0 2.9 2 1 0 2 2 2 1 LIM-domain binding protein LID PF17916.1 VBB26194.1 - 5.8e-19 67.4 7.0 1.1e-18 66.5 7.0 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) Erv26 PF04148.13 VBB26194.1 - 0.13 12.0 0.7 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Transmembrane adaptor Erv26 Neur_chan_LBD PF02931.23 VBB26195.1 - 2.9e-11 43.2 2.0 4.5e-11 42.6 0.7 1.9 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain MFS_1 PF07690.16 VBB26196.1 - 2.9e-31 108.7 29.9 1.4e-24 86.7 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 VBB26196.1 - 0.00053 19.4 19.3 0.048 13.0 9.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Histone PF00125.24 VBB26197.1 - 4.7e-38 130.5 3.0 6e-38 130.2 2.7 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 VBB26197.1 - 1.7e-05 24.9 0.2 4.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 VBB26197.1 - 0.00025 21.3 0.1 0.00048 20.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 VBB26197.1 - 0.0067 16.7 0.6 0.015 15.6 0.6 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 VBB26197.1 - 0.0092 16.1 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Acyltransferase PF01553.21 VBB26198.1 - 3.1e-17 62.4 0.0 6.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Hormone_recep PF00104.30 VBB26199.1 - 2.3e-22 79.6 0.5 2.3e-22 79.6 0.5 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 VBB26199.1 - 2e-21 76.2 18.5 1.2e-17 64.2 5.3 3.2 4 0 0 4 4 4 2 Zinc finger, C4 type (two domains) Vac14_Fab1_bd PF12755.7 VBB26200.1 - 0.0096 16.5 0.1 0.067 13.8 0.1 2.6 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 VBB26200.1 - 0.059 13.7 0.1 5.2 7.6 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 VBB26200.1 - 0.12 12.7 0.1 2.6 8.5 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats EF-hand_7 PF13499.6 VBB26201.1 - 5e-05 23.7 0.8 0.13 12.7 0.0 4.2 4 1 0 4 4 4 1 EF-hand domain pair Herpes_BLRF2 PF05812.12 VBB26201.1 - 0.0072 16.5 1.5 0.0072 16.5 1.5 3.7 3 0 0 3 3 3 1 Herpesvirus BLRF2 protein EF-hand_8 PF13833.6 VBB26201.1 - 0.0081 16.0 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 VBB26201.1 - 0.047 14.0 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain DUF1664 PF07889.12 VBB26201.1 - 0.087 12.9 13.9 0.065 13.3 4.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_S20p PF01649.18 VBB26201.1 - 0.16 12.6 0.1 0.16 12.6 0.1 4.0 4 2 1 5 5 4 0 Ribosomal protein S20 A_amylase_inhib PF01356.19 VBB26201.1 - 0.23 11.5 0.2 0.47 10.5 0.2 1.4 1 0 0 1 1 1 0 Alpha amylase inhibitor DASH_Hsk3 PF08227.11 VBB26201.1 - 1.1 9.7 7.3 2.5 8.5 0.1 4.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Arc_PepC_II PF06847.11 VBB26201.1 - 2.3 8.8 8.4 4 8.0 0.4 4.0 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II FAM184 PF15665.5 VBB26201.1 - 4.4 7.0 32.7 0.55 10.0 0.8 3.7 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 VBB26201.1 - 5.1 7.1 11.3 4.7 7.2 0.0 4.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 VBB26201.1 - 7.3 6.5 6.8 1.2 9.0 0.3 3.1 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF4407 PF14362.6 VBB26201.1 - 8.8 5.6 13.6 4.2 6.6 7.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DENN PF02141.21 VBB26202.1 - 5e-22 78.8 0.1 8.4e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 VBB26202.1 - 0.0014 19.4 0.1 0.0033 18.2 0.1 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 VBB26202.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 dDENN domain Lustrin_cystein PF14625.6 VBB26203.1 - 1.7e-33 114.7 93.8 1.3e-08 35.1 8.0 8.0 8 0 0 8 8 8 6 Lustrin, cysteine-rich repeated domain EB PF01683.18 VBB26203.1 - 8.3e-16 58.0 16.0 3.6e-12 46.4 5.1 7.4 6 2 1 7 7 7 3 EB module Inhibitor_I36 PF03995.13 VBB26203.1 - 0.32 10.9 23.5 0.98 9.4 1.3 5.1 4 0 0 4 4 4 0 Peptidase inhibitor family I36 Acetyltransf_3 PF13302.7 VBB26204.1 - 1.2e-10 42.2 0.2 2e-10 41.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB26204.1 - 9.4e-06 25.9 0.1 1.5e-05 25.2 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 VBB26204.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 VBB26204.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 VBB26204.1 - 0.019 15.1 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 VBB26204.1 - 0.032 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rad9 PF04139.13 VBB26205.1 - 8.8e-56 189.1 2.1 1.1e-55 188.8 2.1 1.1 1 0 0 1 1 1 1 Rad9 FIIND PF13553.6 VBB26205.1 - 0.019 14.4 0.4 0.037 13.4 0.3 1.4 1 1 0 1 1 1 0 Function to find WD40 PF00400.32 VBB26206.1 - 6.9e-57 188.1 21.3 5.8e-08 33.3 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB26206.1 - 2.2e-17 63.2 1.7 0.0057 16.9 0.0 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 VBB26206.1 - 6.3e-08 31.7 2.2 0.031 12.9 0.2 4.4 2 1 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.11 VBB26206.1 - 3.1e-05 23.7 0.1 6.3e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 VBB26206.1 - 0.004 16.0 1.0 0.11 11.2 0.1 3.2 2 1 0 2 2 2 1 Nup133 N terminal like CALCOCO1 PF07888.11 VBB26206.1 - 0.1 11.4 0.4 0.19 10.6 0.1 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BRE1 PF08647.11 VBB26206.1 - 0.11 12.6 0.3 0.24 11.5 0.3 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Pox_A_type_inc PF04508.12 VBB26206.1 - 0.13 12.1 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ribosomal_S17 PF00366.20 VBB26207.1 - 0.0024 17.9 0.0 0.0068 16.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S17 POP1 PF06978.11 VBB26208.1 - 5.5e-24 85.3 31.8 2.1e-19 70.4 3.5 3.4 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 VBB26208.1 - 8.2e-20 70.9 0.0 8.2e-20 70.9 0.0 3.0 3 0 0 3 3 3 1 POPLD (NUC188) domain VCBS PF13517.6 VBB26208.1 - 1.6e-19 70.3 12.7 7.4e-09 36.1 0.7 5.6 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 VBB26208.1 - 1.1e-07 31.8 24.4 5.4e-05 23.2 0.0 5.9 6 0 0 6 6 6 3 FG-GAP repeat GCV_T PF01571.21 VBB26208.1 - 0.00022 20.7 0.0 3.7 6.8 0.0 3.6 4 0 0 4 4 4 2 Aminomethyltransferase folate-binding domain AAA_23 PF13476.6 VBB26208.1 - 0.28 11.7 6.5 0.66 10.4 6.5 1.6 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.12 VBB26208.1 - 0.88 8.9 8.6 7.1 5.9 7.9 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Patched PF02460.18 VBB26210.1 - 9.2e-185 616.1 17.2 6.2e-183 610.1 17.2 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB26210.1 - 1.4e-26 93.2 5.4 1.4e-26 93.2 5.4 3.5 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 VBB26210.1 - 0.0057 16.1 7.2 0.0057 16.1 7.2 2.6 2 1 0 2 2 2 1 Protein export membrane protein Mlh1_C PF16413.5 VBB26211.1 - 3.7e-64 216.7 2.6 5.8e-64 216.1 2.6 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 VBB26211.1 - 5.3e-22 77.7 0.1 1.1e-21 76.7 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 VBB26211.1 - 5.4e-13 48.9 0.0 1.6e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 VBB26211.1 - 5.3e-07 30.1 0.0 1.9e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Collagen PF01391.18 VBB26212.1 - 4.9e-26 90.3 101.1 6.2e-11 41.9 33.8 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26212.1 - 6.8e-11 42.1 2.6 9.9e-11 41.5 2.6 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB26213.1 - 2.7e-26 91.1 104.4 7.1e-10 38.5 36.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26213.1 - 1.9e-16 59.8 2.2 2.4e-16 59.5 2.2 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain SET PF00856.28 VBB26214.1 - 7.9e-20 71.9 0.1 2.3e-19 70.4 0.1 1.9 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 VBB26214.1 - 8.7e-16 58.5 5.2 8.7e-16 58.5 5.2 2.8 3 0 0 3 3 3 1 Pre-SET motif TUDOR_5 PF18359.1 VBB26214.1 - 1.8e-06 27.5 0.1 6.6e-05 22.5 0.1 2.5 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 MBD PF01429.19 VBB26214.1 - 0.00058 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain Tudor_4 PF18358.1 VBB26214.1 - 0.0023 17.5 0.2 0.0063 16.1 0.2 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain DUF4537 PF15057.6 VBB26214.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TUDOR PF00567.24 VBB26214.1 - 0.097 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Tudor domain SH2 PF00017.24 VBB26216.1 - 6.2e-14 51.9 0.1 1.5e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 VBB26216.1 - 0.0011 19.1 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Myosin_head PF00063.21 VBB26217.1 - 3.8e-176 587.2 2.8 6.9e-124 414.5 4.2 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Patched PF02460.18 VBB26217.1 - 1.9e-78 264.5 33.0 1.3e-51 175.7 8.5 2.2 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 VBB26217.1 - 3.9e-61 206.7 11.0 3.9e-61 206.7 11.0 1.9 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 VBB26217.1 - 5.1e-51 172.5 7.1 5.1e-51 172.5 7.1 3.2 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation IQ PF00612.27 VBB26217.1 - 0.0007 19.2 11.3 0.21 11.5 0.8 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif Folate_rec PF03024.14 VBB26217.1 - 0.0019 18.1 3.1 0.0064 16.4 3.1 1.9 1 0 0 1 1 1 1 Folate receptor family AAA_22 PF13401.6 VBB26217.1 - 0.021 15.1 0.0 0.07 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 VBB26217.1 - 0.027 14.9 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 VBB26217.1 - 0.18 12.3 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MyTH4 PF00784.17 VBB26218.1 - 2.6e-32 111.5 0.1 3.9e-30 104.5 0.0 3.3 2 1 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 VBB26218.1 - 2e-12 47.5 1.5 3e-06 27.6 0.2 3.1 3 0 0 3 3 3 2 FERM central domain FERM_N PF09379.10 VBB26218.1 - 6.1e-09 35.7 0.1 0.0019 18.1 0.0 2.5 2 0 0 2 2 2 2 FERM N-terminal domain RA PF00788.23 VBB26218.1 - 0.003 18.2 0.0 0.53 11.0 0.0 2.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IRS PF02174.17 VBB26218.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Kunitz_BPTI PF00014.23 VBB26220.1 - 1.3e-103 339.1 64.9 1.3e-17 63.7 4.2 7.7 7 0 0 7 7 7 7 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 VBB26220.1 - 1.3e-53 179.1 88.3 2.8e-09 37.2 7.1 8.2 7 0 0 7 7 7 7 Lustrin, cysteine-rich repeated domain Orthopox_A5L PF06193.11 VBB26220.1 - 0.73 9.2 14.1 1.3 8.4 14.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Patched PF02460.18 VBB26221.1 - 4.1e-231 769.4 12.5 4.8e-231 769.2 12.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB26221.1 - 8.5e-40 136.1 11.9 7.3e-37 126.6 5.5 3.3 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 VBB26221.1 - 0.0041 16.1 7.2 0.0041 16.1 7.2 2.2 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 VBB26221.1 - 0.0044 16.4 9.1 0.0044 16.4 9.1 2.6 2 1 0 2 2 2 1 Protein export membrane protein Collagen PF01391.18 VBB26222.1 - 0.0024 17.6 18.2 0.0056 16.4 18.2 1.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) WW PF00397.26 VBB26223.1 - 3.9e-18 65.2 20.7 4.7e-10 39.4 3.3 3.0 3 0 0 3 3 3 2 WW domain FF PF01846.19 VBB26223.1 - 2e-12 47.1 1.4 2e-12 47.1 1.4 1.9 2 0 0 2 2 2 1 FF domain Glyco_hyd_101C PF17451.2 VBB26223.1 - 0.043 14.1 4.3 2 8.7 0.4 3.0 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain MRP-S23 PF10484.9 VBB26224.1 - 1.7e-31 109.1 0.2 2.3e-31 108.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 VBB26224.1 - 0.00026 20.6 1.2 0.011 15.4 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 Erp_C PF06780.11 VBB26224.1 - 0.019 15.0 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Erp protein C-terminus RPN6_N PF18055.1 VBB26226.1 - 2.1e-29 102.2 3.1 3.6e-29 101.5 0.3 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 VBB26226.1 - 1.1e-15 58.1 2.5 2.1e-15 57.1 0.0 2.8 3 1 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 VBB26226.1 - 7.6e-12 44.8 0.7 1.6e-11 43.8 0.7 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 VBB26226.1 - 0.0038 17.5 5.4 0.088 13.1 1.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat CENP-K PF11802.8 VBB26226.1 - 0.05 13.2 4.4 0.11 12.1 4.4 1.5 1 0 0 1 1 1 0 Centromere-associated protein K TPR_16 PF13432.6 VBB26226.1 - 0.1 13.3 2.4 0.25 12.0 0.3 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB26226.1 - 0.1 13.1 7.2 6.7 7.3 0.6 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 VBB26226.1 - 2 9.5 5.4 44 5.3 0.2 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MutS_III PF05192.18 VBB26226.1 - 2.8 8.1 8.8 20 5.3 8.8 2.3 1 1 0 1 1 1 0 MutS domain III Not1 PF04054.15 VBB26227.1 - 7e-132 439.8 4.9 3.1e-131 437.7 4.9 2.2 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 VBB26227.1 - 1.4e-80 269.9 7.7 3e-80 268.8 7.7 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 VBB26227.1 - 1.3e-60 203.9 0.2 3.4e-60 202.5 0.2 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 VBB26227.1 - 9.5e-45 152.1 2.5 9.5e-45 152.1 2.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 VBB26227.1 - 3.7e-29 101.7 0.1 2.3e-28 99.2 0.0 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF1778 PF08681.11 VBB26227.1 - 0.092 12.7 0.2 0.3 11.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) MFS_5 PF05631.14 VBB26228.1 - 1.2e-113 379.6 17.0 1.7e-113 379.2 17.0 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 VBB26228.1 - 3e-14 52.7 33.7 8.3e-11 41.4 13.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 VBB26229.1 - 1.2e-25 89.9 2.6 2.2e-10 41.0 0.5 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB26229.1 - 4.9e-20 69.5 2.1 6.4e-05 23.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 VBB26229.1 - 5.4e-19 68.0 2.0 2.4e-08 34.1 0.1 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 VBB26229.1 - 1.1e-17 63.6 6.0 4.3e-05 23.8 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 VBB26229.1 - 3.4e-17 62.6 3.5 1.6e-09 38.1 0.2 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 VBB26229.1 - 0.047 14.1 1.3 0.061 13.8 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HLH PF00010.26 VBB26230.1 - 8e-13 48.1 0.6 1.4e-12 47.3 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HD_assoc PF13286.6 VBB26230.1 - 0.036 14.6 0.5 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Phosphohydrolase-associated domain tRNA-synt_2 PF00152.20 VBB26231.1 - 2.5e-76 256.8 0.0 3.7e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 VBB26231.1 - 1.5e-08 34.5 1.5 3.8e-08 33.2 1.5 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 VBB26231.1 - 0.0022 17.5 0.1 2.2 7.7 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.8 VBB26231.1 - 1 8.2 8.9 1.6 7.6 8.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 APG6_N PF17675.1 VBB26231.1 - 2.3 8.7 12.1 0.72 10.4 9.2 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Phosphorylase PF00343.20 VBB26234.1 - 0 1049.8 0.0 2.2e-221 737.0 0.0 2.1 1 1 1 2 2 2 2 Carbohydrate phosphorylase NRN1 PF15056.6 VBB26234.1 - 0.078 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Neuritin protein family INTS5_C PF14838.6 VBB26235.1 - 2.5e-191 638.0 6.8 3e-191 637.7 6.8 1.1 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 VBB26235.1 - 3.9e-48 163.8 0.7 1.2e-47 162.2 0.0 2.2 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus 7tm_1 PF00001.21 VBB26237.1 - 1.7e-07 30.8 0.2 1.7e-07 30.8 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Lig_chan PF00060.26 VBB26239.1 - 3.1e-55 186.1 0.4 5.2e-55 185.4 0.4 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 VBB26239.1 - 4.5e-38 130.0 0.0 1.1e-37 128.7 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 VBB26239.1 - 2.5e-25 89.2 0.0 5.7e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Collagen PF01391.18 VBB26240.1 - 8.7e-22 76.7 104.9 0.0037 17.0 12.2 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26240.1 - 1.3e-18 66.8 1.8 1.9e-18 66.3 1.8 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB26241.1 - 4.4e-23 80.8 89.9 1.2e-08 34.6 33.8 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) LRR_5 PF13306.6 VBB26241.1 - 8e-17 61.4 36.1 7.6e-08 32.4 0.1 5.7 3 2 2 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 VBB26241.1 - 2.4e-14 52.8 6.2 0.00038 20.2 0.0 7.7 5 3 3 8 8 8 5 Leucine rich repeat Col_cuticle_N PF01484.17 VBB26241.1 - 3.2e-11 43.1 0.9 6.4e-11 42.1 0.9 1.6 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Pentapeptide_3 PF13576.6 VBB26241.1 - 0.00021 21.4 0.3 0.014 15.6 0.0 3.4 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) Collagen PF01391.18 VBB26242.1 - 3.4e-25 87.6 86.4 8.8e-10 38.2 30.2 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26242.1 - 4.8e-16 58.5 1.0 7.5e-16 57.9 1.0 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Lectin_N PF03954.14 VBB26242.1 - 0.086 12.6 0.3 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Peptidase_M3 PF01432.20 VBB26243.1 - 2.9e-82 277.4 0.6 4.3e-82 276.8 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 VBB26243.1 - 0.35 9.6 5.1 0.099 11.4 0.5 2.2 2 1 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase MitMem_reg PF13012.6 VBB26244.1 - 1.7e-23 83.2 0.3 3.2e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 VBB26244.1 - 2.2e-17 63.1 0.3 4.3e-17 62.2 0.3 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Diphthami_syn_2 PF01902.17 VBB26244.1 - 0.094 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase Chromo_2 PF18704.1 VBB26244.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 Gln-synt_C PF00120.24 VBB26245.1 - 2.2e-19 69.7 0.0 7.6e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 VBB26245.1 - 3.1e-09 36.4 0.0 5.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Collagen PF01391.18 VBB26246.1 - 1.5e-24 85.5 73.7 2.8e-10 39.8 27.1 3.5 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26246.1 - 2.4e-13 49.9 3.9 3.2e-13 49.5 3.9 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain zf-C3HC4_3 PF13920.6 VBB26248.1 - 2.7e-10 39.9 5.6 4.2e-10 39.3 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB26248.1 - 7.8e-10 38.5 6.0 1.2e-09 37.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB26248.1 - 3.8e-09 36.7 9.1 3.8e-09 36.7 9.1 1.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB26248.1 - 1.1e-08 34.8 8.5 1.8e-08 34.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB26248.1 - 6e-08 32.6 4.5 6e-07 29.4 2.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 VBB26248.1 - 1.5e-07 31.1 6.9 2.4e-07 30.5 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 VBB26248.1 - 9.5e-07 28.7 5.3 1.9e-06 27.7 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 VBB26248.1 - 3.5e-05 24.0 6.1 7.5e-05 22.9 6.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 VBB26248.1 - 3.5e-05 23.8 2.3 6.3e-05 23.0 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 VBB26248.1 - 0.00016 21.7 6.7 0.0003 20.9 6.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 VBB26248.1 - 0.0012 18.3 0.1 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 VBB26248.1 - 0.013 15.4 1.3 0.025 14.5 1.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 VBB26248.1 - 0.023 14.8 1.1 0.051 13.7 1.1 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 VBB26248.1 - 0.032 14.0 5.4 0.072 12.9 5.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 VBB26248.1 - 0.042 14.1 7.4 0.11 12.7 2.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 VBB26248.1 - 0.11 12.3 3.1 0.2 11.6 3.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 VBB26248.1 - 0.33 10.6 5.2 0.59 9.8 5.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Kelch_1 PF01344.25 VBB26249.1 - 3.2e-57 189.9 2.6 1.4e-13 50.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 VBB26249.1 - 4.1e-33 113.6 0.1 7.9e-33 112.6 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 VBB26249.1 - 5.1e-24 84.7 0.1 9.9e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 VBB26249.1 - 6.2e-20 70.7 3.5 0.0029 17.8 0.0 6.8 2 1 4 6 6 6 5 Kelch motif Kelch_4 PF13418.6 VBB26249.1 - 4.5e-15 55.4 8.8 0.046 13.7 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 VBB26249.1 - 9.2e-12 45.0 6.9 0.022 15.1 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 VBB26249.1 - 2.6e-11 43.0 4.9 0.66 10.1 0.3 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 VBB26249.1 - 4.7e-06 26.5 3.7 1.4 9.0 0.0 5.5 4 1 1 5 5 5 2 Kelch motif SH3_2 PF07653.17 VBB26249.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain EFG_C PF00679.24 VBB26250.1 - 5.4e-17 61.6 0.1 6.9e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor G C-terminus LcrG PF07216.12 VBB26250.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 LcrG protein Fzo_mitofusin PF04799.13 VBB26251.1 - 0.027 14.0 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF773 PF05600.12 VBB26252.1 - 7.6e-97 325.1 13.9 9.3e-75 252.3 6.8 2.8 2 1 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 Prominin PF05478.11 VBB26252.1 - 0.0045 15.0 4.4 0.021 12.8 3.5 1.9 2 0 0 2 2 2 1 Prominin DUF29 PF01724.16 VBB26252.1 - 0.037 14.3 8.0 2.1 8.5 1.5 3.3 3 2 0 3 3 3 0 Domain of unknown function DUF29 SSL_OB PF09199.10 VBB26252.1 - 0.59 10.5 3.7 4.8 7.6 0.1 3.0 3 0 0 3 3 3 0 Staphylococcal superantigen-like OB-fold domain 60KD_IMP PF02096.20 VBB26252.1 - 0.59 10.0 5.2 0.33 10.9 2.9 1.7 1 1 1 2 2 2 0 60Kd inner membrane protein adh_short PF00106.25 VBB26253.1 - 3.8e-24 85.2 0.0 9.9e-18 64.3 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 VBB26253.1 - 1.7e-15 57.2 0.0 2.5e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB26253.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 VBB26253.1 - 0.016 14.7 0.5 0.17 11.3 0.0 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family TRAF_BIRC3_bd PF16673.5 VBB26253.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Polysacc_synt_2 PF02719.15 VBB26253.1 - 0.077 12.1 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FERM_M PF00373.18 VBB26254.1 - 5.7e-39 133.2 0.5 3.6e-38 130.6 0.7 2.2 2 1 0 2 2 2 1 FERM central domain Kindlin_2_N PF18124.1 VBB26254.1 - 1.1e-32 112.0 0.6 2.7e-32 110.8 0.6 1.7 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 VBB26254.1 - 7.3e-07 29.7 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 VBB26254.1 - 0.1 12.5 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 FERM N-terminal domain Gal-bind_lectin PF00337.22 VBB26255.1 - 3e-43 146.5 0.4 1.4e-31 108.8 0.0 3.1 2 1 1 3 3 3 3 Galactoside-binding lectin Y2_Tnp PF04986.13 VBB26255.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative transposase Ribosomal_S11 PF00411.19 VBB26256.1 - 1.1e-20 74.1 0.9 1.5e-20 73.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Ion_trans_2 PF07885.16 VBB26257.1 - 9.5e-18 63.9 17.8 8.1e-16 57.8 0.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB26257.1 - 0.0002 20.7 2.3 0.00026 20.3 0.4 2.0 2 0 0 2 2 2 1 Ion transport protein HDOD PF08668.12 VBB26257.1 - 0.0057 16.2 0.0 0.039 13.4 0.0 2.3 2 0 0 2 2 2 1 HDOD domain PBP1_TM PF14812.6 VBB26257.1 - 0.75 10.2 3.6 2 8.8 3.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 VBB26257.1 - 7.2 7.1 10.1 15 6.0 10.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Kunitz_BPTI PF00014.23 VBB26258.1 - 1.4e-13 50.8 4.9 3.3e-13 49.7 4.9 1.6 1 1 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain CBM_3 PF00942.18 VBB26258.1 - 0.05 14.0 0.0 0.063 13.7 0.0 1.2 1 0 0 1 1 1 0 Cellulose binding domain Ost5 PF05251.12 VBB26259.1 - 1.2e-26 92.8 7.1 1.2e-26 92.7 7.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 PRA1 PF03208.19 VBB26259.1 - 0.084 12.5 6.4 0.097 12.3 6.4 1.1 1 0 0 1 1 1 0 PRA1 family protein DUF485 PF04341.12 VBB26259.1 - 1.4 8.9 9.2 1.7 8.7 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Serinc PF03348.15 VBB26260.1 - 7e-154 512.9 21.3 7.9e-154 512.7 21.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YfhO PF09586.10 VBB26260.1 - 0.12 10.6 13.3 0.44 8.7 2.4 2.4 1 1 1 2 2 2 0 Bacterial membrane protein YfhO ZZ PF00569.17 VBB26261.1 - 5.8e-10 38.8 9.0 1e-09 38.0 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 VBB26261.1 - 3.5e-06 26.9 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain SL4P PF17618.2 VBB26261.1 - 0.0019 18.2 0.2 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized Strongylid L4 protein C1_2 PF03107.16 VBB26261.1 - 0.02 15.2 9.8 0.05 13.9 9.8 1.7 1 0 0 1 1 1 0 C1 domain DUF3731 PF12531.8 VBB26261.1 - 0.071 12.9 1.1 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 DNA-K related protein UBA_5 PF16577.5 VBB26261.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 UBA domain SBP_bac_5 PF00496.22 VBB26261.1 - 0.16 10.9 3.8 0.15 11.0 2.1 1.8 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF4078 PF13300.6 VBB26261.1 - 8.4 6.8 11.2 0.2 12.0 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) Adenylsucc_synt PF00709.21 VBB26262.1 - 2.6e-162 540.6 0.0 2.9e-162 540.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase ARF7EP_C PF14949.6 VBB26263.1 - 1.6e-28 99.4 3.2 2e-28 99.1 3.2 1.1 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Pkinase PF00069.25 VBB26264.1 - 6.1e-70 235.6 0.0 1.2e-69 234.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26264.1 - 2.1e-44 151.8 0.0 3.6e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 VBB26264.1 - 2.4e-15 56.6 0.0 9.6e-15 54.7 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 VBB26264.1 - 2.1e-07 30.6 0.1 4.7e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 VBB26264.1 - 2.2e-07 30.0 0.4 3e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 VBB26264.1 - 0.0013 18.4 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DSHCT PF08148.12 VBB26264.1 - 0.0088 15.7 0.7 0.036 13.7 0.6 2.1 1 1 0 1 1 1 1 DSHCT (NUC185) domain Haspin_kinase PF12330.8 VBB26264.1 - 0.01 14.8 0.3 0.019 13.9 0.3 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 VBB26264.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family V_ATPase_I PF01496.19 VBB26265.1 - 1.5e-293 975.8 3.9 1.7e-293 975.6 3.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Med9 PF07544.13 VBB26265.1 - 0.056 13.5 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_M24 PF00557.24 VBB26266.1 - 5.2e-51 173.3 0.1 6.3e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 VBB26266.1 - 5.2e-18 65.1 7.9 1.1e-17 64.0 7.9 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 VBB26266.1 - 0.00043 20.3 4.9 0.0012 18.9 4.9 1.8 1 0 0 1 1 1 1 MYND finger ATP-cone PF03477.16 VBB26266.1 - 0.0084 16.7 0.1 1.4 9.5 0.1 2.3 2 0 0 2 2 2 1 ATP cone domain zf-HIT PF04438.16 VBB26266.1 - 0.3 11.0 7.9 0.75 9.7 7.9 1.7 1 0 0 1 1 1 0 HIT zinc finger FYVE PF01363.21 VBB26267.1 - 9.8e-15 54.5 4.2 2.4e-14 53.2 4.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 VBB26267.1 - 1.6e-11 44.6 0.2 2.3e-08 34.5 0.2 3.0 3 0 0 3 3 3 2 PH domain RhoGEF PF00621.20 VBB26267.1 - 3.6e-11 43.6 2.8 3.6e-11 43.6 2.8 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_13 PF16652.5 VBB26267.1 - 6e-07 29.4 1.3 1.9e-06 27.8 1.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 VBB26267.1 - 1.5e-05 25.0 0.8 1.5e-05 25.0 0.8 2.3 3 0 0 3 3 3 1 PH domain PH_4 PF15404.6 VBB26267.1 - 0.00075 19.3 0.0 0.0023 17.7 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 VBB26267.1 - 0.012 15.9 0.2 0.048 13.9 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain zf-RING_4 PF14570.6 VBB26267.1 - 0.049 13.4 5.5 0.14 12.0 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PH_2 PF08458.10 VBB26267.1 - 0.11 12.9 0.1 0.35 11.2 0.1 1.9 1 0 0 1 1 1 0 Plant pleckstrin homology-like region zf-UDP PF14569.6 VBB26267.1 - 0.2 11.8 2.5 0.43 10.7 2.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger IBR PF01485.21 VBB26267.1 - 1.1 9.5 7.2 0.31 11.3 3.1 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SPA PF08616.10 VBB26268.1 - 1.4e-12 47.5 0.3 3.6e-12 46.2 0.3 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 VBB26268.1 - 2.8e-07 29.6 0.1 1.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Transport protein Avl9 DENN PF02141.21 VBB26268.1 - 0.0015 18.5 1.9 0.024 14.6 0.9 2.7 2 1 0 2 2 2 1 DENN (AEX-3) domain TGF_beta PF00019.20 VBB26270.1 - 2e-30 105.9 0.8 3.8e-30 104.9 0.8 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain Laminin_EGF PF00053.24 VBB26271.1 - 0.0052 16.9 37.3 3.6 7.8 7.0 4.6 1 1 3 4 4 4 4 Laminin EGF domain DUF1179 PF06678.11 VBB26271.1 - 0.093 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) hEGF PF12661.7 VBB26271.1 - 0.12 13.1 0.2 0.12 13.1 0.2 5.7 4 1 0 4 4 4 0 Human growth factor-like EGF G-alpha PF00503.20 VBB26272.1 - 3.8e-105 351.9 0.4 5e-105 351.5 0.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB26272.1 - 7.2e-11 41.8 0.6 4.7e-10 39.2 0.2 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 VBB26273.1 - 0.14 11.3 1.3 0.15 11.2 0.7 1.3 1 1 0 1 1 1 0 G-protein alpha subunit LEM PF03020.15 VBB26275.1 - 5.4e-17 61.1 0.1 1.5e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 LEM domain zf-H2C2_2 PF13465.6 VBB26276.1 - 9.8e-24 82.7 29.9 2.3e-07 30.9 0.1 7.6 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 VBB26276.1 - 2.7e-17 62.2 41.6 0.012 16.0 0.5 8.0 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26276.1 - 2.4e-13 49.7 39.1 0.021 15.6 0.7 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 VBB26276.1 - 0.011 15.7 3.8 2.8 8.1 0.2 3.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-met PF12874.7 VBB26276.1 - 0.021 15.2 12.0 3.9 8.0 0.0 5.9 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 VBB26276.1 - 0.025 14.3 12.1 3 7.7 0.0 5.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-RING_7 PF02591.15 VBB26276.1 - 0.029 14.6 7.3 0.24 11.6 0.0 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain TF_Zn_Ribbon PF08271.12 VBB26276.1 - 0.03 13.8 1.3 13 5.4 0.1 4.0 3 0 0 3 3 3 0 TFIIB zinc-binding Ribosomal_S27e PF01667.17 VBB26276.1 - 0.047 13.4 2.7 1.8 8.4 0.2 3.5 3 0 0 3 3 3 0 Ribosomal protein S27 zf_C2H2_6 PF18450.1 VBB26276.1 - 0.11 12.2 13.5 0.92 9.3 0.0 5.3 6 0 0 6 6 6 0 Zinc Finger domain zinc_ribbon_15 PF17032.5 VBB26276.1 - 0.14 12.9 13.2 0.82 10.5 0.4 4.4 4 1 1 5 5 5 0 zinc-ribbon family zinc_ribbon_12 PF11331.8 VBB26276.1 - 0.22 11.3 4.9 2.8 7.8 0.2 2.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain THDPS_N_2 PF14805.6 VBB26276.1 - 0.41 10.9 2.2 0.61 10.4 0.5 2.0 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PyrI_C PF02748.15 VBB26276.1 - 1.5 8.8 9.7 9.8 6.2 0.2 4.5 3 2 2 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 VBB26276.1 - 3.9 7.9 12.3 6.7 7.1 0.0 5.7 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 VBB26276.1 - 4.8 7.3 10.9 4.7 7.3 0.0 4.7 5 0 0 5 5 5 0 Zinc-finger domain Ion_trans_2 PF07885.16 VBB26277.1 - 1.6e-10 40.8 12.4 1.9e-10 40.5 0.2 3.0 2 1 0 2 2 2 1 Ion channel Thioredoxin PF00085.20 VBB26278.1 - 1.9e-59 198.0 0.2 2.5e-29 101.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 VBB26278.1 - 1e-21 77.7 1.8 1.7e-15 57.4 2.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 VBB26278.1 - 3.1e-09 37.0 0.1 0.15 12.4 0.0 4.9 3 2 2 5 5 5 3 Thioredoxin-like Thioredoxin_2 PF13098.6 VBB26278.1 - 6e-09 36.3 1.7 0.00016 22.1 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 VBB26278.1 - 4.9e-07 29.8 0.0 0.059 13.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 VBB26278.1 - 8.5e-07 28.6 0.0 0.00044 19.7 0.0 3.3 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 VBB26278.1 - 1.3e-05 25.1 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 VBB26278.1 - 0.00047 19.9 0.1 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin SNF2_N PF00176.23 VBB26279.1 - 1.3e-66 224.7 1.5 2.5e-65 220.5 1.2 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 VBB26279.1 - 9.9e-28 95.8 12.6 6.5e-19 67.6 0.7 4.0 4 0 0 4 4 3 2 Chromo (CHRromatin Organisation MOdifier) domain CDH1_2_SANT_HL1 PF18375.1 VBB26279.1 - 7.4e-23 81.0 0.7 7.4e-23 81.0 0.7 4.2 3 1 0 3 3 3 1 CDH1/2 SANT-Helical linker 1 Helicase_C PF00271.31 VBB26279.1 - 2.3e-19 69.7 0.0 7.2e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ubiquitin PF00240.23 VBB26279.1 - 7.4e-17 60.9 0.4 2e-16 59.5 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin family ResIII PF04851.15 VBB26279.1 - 1.1e-10 41.8 0.0 4.5e-10 39.8 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA PF00627.31 VBB26279.1 - 1.5e-08 34.3 0.2 3.8e-08 33.1 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF4208 PF13907.6 VBB26279.1 - 2.5e-08 34.3 0.3 2.5e-08 34.3 0.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Rad60-SLD PF11976.8 VBB26279.1 - 2e-07 30.7 0.2 5.8e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 VBB26279.1 - 0.00026 20.9 18.1 0.00061 19.7 0.6 5.0 3 2 1 5 5 4 2 STI1 domain Rad60-SLD_2 PF13881.6 VBB26279.1 - 0.053 13.6 0.1 0.26 11.4 0.1 2.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 VBB26279.1 - 0.071 12.9 14.9 0.91 9.3 1.2 4.7 2 2 3 5 5 5 0 XPC-binding domain DUF2407 PF10302.9 VBB26279.1 - 0.11 13.1 0.0 0.11 13.1 0.0 3.8 4 0 0 4 4 2 0 DUF2407 ubiquitin-like domain ArfGap PF01412.18 VBB26281.1 - 4.9e-42 142.7 0.1 9.3e-42 141.8 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 VBB26282.1 - 1.6e-06 28.6 0.1 1.1e-05 25.9 0.0 2.3 2 0 0 2 2 2 1 PH domain RUN PF02759.19 VBB26282.1 - 0.00028 20.8 0.2 0.00078 19.4 0.2 1.7 1 0 0 1 1 1 1 RUN domain ENTH PF01417.20 VBB26283.1 - 5e-47 159.0 0.1 9.5e-47 158.1 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 VBB26283.1 - 1e-09 37.8 0.1 1.4e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 VBB26283.1 - 8.2e-05 22.5 0.2 0.00015 21.6 0.2 1.3 1 0 0 1 1 1 1 VHS domain AKAP95 PF04988.12 VBB26284.1 - 0.0044 17.3 4.1 1 9.6 0.2 3.0 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-H2C2_2 PF13465.6 VBB26284.1 - 0.0079 16.6 25.5 0.022 15.1 0.8 5.4 6 0 0 6 6 6 2 Zinc-finger double domain CCDC117 PF15810.5 VBB26284.1 - 0.035 14.4 2.0 0.08 13.3 0.1 2.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 117 zf-C2H2_4 PF13894.6 VBB26284.1 - 8.3 7.5 41.3 0.31 12.0 0.5 6.7 7 0 0 7 7 7 0 C2H2-type zinc finger Neur_chan_memb PF02932.16 VBB26285.1 - 1.5e-65 221.6 5.8 2.3e-65 221.0 5.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 VBB26285.1 - 9.1e-58 195.2 0.1 1.3e-49 168.5 0.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Claudin_2 PF13903.6 VBB26285.1 - 0.73 9.5 5.3 0.23 11.2 1.9 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF832 PF05734.11 VBB26286.1 - 0.038 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Zona_pellucida PF00100.23 VBB26287.1 - 1.2e-13 51.4 2.1 1.2e-13 51.4 2.1 1.5 1 1 0 1 1 1 1 Zona pellucida-like domain ANF_receptor PF01094.28 VBB26288.1 - 1.3e-78 264.6 0.0 1.7e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 VBB26288.1 - 4.8e-55 186.9 22.7 1.7e-54 185.1 22.4 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 VBB26288.1 - 5.5e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein NCD3G PF07562.14 VBB26288.1 - 3.2e-07 30.2 7.6 7.4e-07 29.0 7.6 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR BaxI_1 PF12811.7 VBB26288.1 - 9.3 5.7 12.9 15 5.0 1.2 2.4 2 0 0 2 2 2 0 Bax inhibitor 1 like GST_C_3 PF14497.6 VBB26289.1 - 5.2e-19 68.3 0.2 9.2e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 VBB26289.1 - 9.4e-14 51.5 0.1 1.9e-12 47.3 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 VBB26289.1 - 1.2e-06 28.7 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 VBB26289.1 - 2e-06 28.1 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 VBB26289.1 - 0.00073 19.8 0.0 0.0091 16.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 VBB26289.1 - 0.0009 20.0 0.0 0.0041 17.8 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 VBB26289.1 - 0.00095 19.1 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAUGI PF06106.11 VBB26289.1 - 0.0048 17.4 0.1 0.011 16.3 0.1 1.5 1 1 0 1 1 1 1 S. aureus uracil DNA glycosylase inhibitor U5_2-snRNA_bdg PF10597.9 VBB26289.1 - 0.029 14.4 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 GST_C_5 PF16865.5 VBB26289.1 - 0.036 14.7 0.3 0.1 13.2 0.2 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 VBB26289.1 - 0.049 13.4 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Galactosyl_T PF01762.21 VBB26291.1 - 2.4e-26 92.8 0.4 3.9e-15 56.2 0.2 2.3 1 1 1 2 2 2 2 Galactosyltransferase Polysacc_synt_4 PF04669.13 VBB26292.1 - 8.4e-11 41.8 0.7 3.2e-08 33.4 0.7 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis Nucleoporin_FG PF13634.6 VBB26292.1 - 2.7e-07 31.3 56.5 0.00054 20.8 12.3 4.3 2 2 1 3 3 3 2 Nucleoporin FG repeat region GrpE PF01025.19 VBB26292.1 - 0.089 12.5 8.4 0.25 11.0 3.4 2.6 2 1 0 2 2 2 0 GrpE DUF836 PF05768.14 VBB26292.1 - 0.11 12.9 1.6 0.4 11.1 0.2 2.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) PolyA_pol_arg_C PF12626.7 VBB26292.1 - 0.15 12.1 1.4 0.41 10.7 1.4 1.7 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus HlyE PF06109.13 VBB26292.1 - 0.37 10.0 2.4 7.7 5.7 0.4 2.3 2 0 0 2 2 2 0 Haemolysin E (HlyE) Ribosomal_L7Ae PF01248.26 VBB26293.1 - 1.3e-27 95.4 1.8 1.8e-27 94.9 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Na_Ca_ex PF01699.24 VBB26294.1 - 1.5e-47 161.3 37.4 1.3e-23 83.7 12.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 VBB26294.1 - 1.1e-19 70.5 4.1 1.5e-09 38.0 0.0 2.3 1 1 1 2 2 2 2 Calx-beta domain Na_Ca_ex_C PF16494.5 VBB26294.1 - 0.001 19.5 0.1 0.0021 18.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Phage_holin_3_6 PF07332.11 VBB26294.1 - 0.072 13.1 0.4 0.072 13.1 0.4 4.4 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III PH_TFIIH PF08567.11 VBB26294.1 - 0.088 13.1 0.2 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain RRM_1 PF00076.22 VBB26295.1 - 2.7e-50 168.1 0.0 1.4e-16 60.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 VBB26295.1 - 1.1e-05 25.3 0.0 4.5 7.4 0.0 3.8 3 0 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 VBB26295.1 - 4.1e-05 23.6 0.0 0.19 11.9 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB26295.1 - 0.062 13.3 0.1 3 7.9 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif GST_N_4 PF17172.4 VBB26296.1 - 5.6e-24 84.8 0.1 9.8e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 VBB26296.1 - 1.6e-23 82.3 0.1 3e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 VBB26296.1 - 2.3e-06 27.9 0.0 4.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 VBB26296.1 - 2e-05 24.5 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DIX PF00778.17 VBB26297.1 - 1.2e-08 34.7 0.3 3.9e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 DIX domain RGS PF00615.19 VBB26297.1 - 8.4e-07 29.3 0.3 6.5e-06 26.4 0.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain APG6_N PF17675.1 VBB26297.1 - 0.14 12.7 1.9 8.4 6.9 0.3 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Phasin PF05597.11 VBB26297.1 - 0.17 11.9 0.4 0.35 10.9 0.4 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Myb_DNA-binding PF00249.31 VBB26298.1 - 0.00031 20.9 0.1 4.5 7.5 0.0 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 VBB26298.1 - 0.67 10.2 4.7 39 4.6 0.0 4.3 4 0 0 4 4 4 0 Myb-like DNA-binding domain Collagen PF01391.18 VBB26299.1 - 5.7e-20 70.8 62.4 7.3e-10 38.5 28.6 3.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26299.1 - 1.8e-06 27.9 8.1 5.6e-05 23.1 8.1 2.1 1 1 0 1 1 1 1 Nematode cuticle collagen N-terminal domain WWE PF02825.20 VBB26300.1 - 4.1e-14 52.9 0.4 6.8e-14 52.2 0.4 1.4 1 0 0 1 1 1 1 WWE domain zf-RING_2 PF13639.6 VBB26300.1 - 8.6e-10 38.8 6.8 1.5e-09 38.0 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 VBB26300.1 - 6.3e-08 32.4 7.1 1.2e-07 31.5 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB26300.1 - 1.7e-07 31.0 8.1 2.9e-07 30.2 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB26300.1 - 1.7e-05 24.7 4.0 1.7e-05 24.7 4.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 VBB26300.1 - 2.1e-05 24.3 12.5 3.5e-05 23.6 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB26300.1 - 0.0002 21.1 12.5 0.00048 19.9 4.4 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 VBB26300.1 - 0.0015 18.7 9.1 0.0041 17.3 9.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 VBB26300.1 - 0.024 14.6 8.7 0.024 14.6 8.7 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 VBB26300.1 - 0.028 14.7 9.7 0.13 12.6 9.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 VBB26300.1 - 0.063 13.1 10.8 0.13 12.1 9.0 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 VBB26300.1 - 0.38 10.5 9.6 0.063 13.0 5.8 1.7 2 0 0 2 2 2 0 RING-like zinc finger Ribosomal_S10 PF00338.22 VBB26301.1 - 2.6e-24 85.3 0.1 3e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e WD40 PF00400.32 VBB26305.1 - 4.7e-23 81.0 2.5 7.8e-07 29.7 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB26305.1 - 2.3e-09 37.4 0.0 0.024 14.9 0.0 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 VBB26305.1 - 0.0019 16.9 0.3 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Presenilin PF01080.17 VBB26306.1 - 4.2 6.0 8.3 5.8 5.6 8.3 1.1 1 0 0 1 1 1 0 Presenilin DUF1387 PF07139.11 VBB26307.1 - 3.3e-15 56.6 3.1 3.3e-15 56.6 3.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1387) SPX PF03105.19 VBB26307.1 - 0.00018 21.6 2.7 0.00021 21.4 1.9 1.3 1 1 0 1 1 1 1 SPX domain DUF1296 PF06972.11 VBB26307.1 - 0.0027 17.8 0.2 0.0083 16.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) YqzH PF14164.6 VBB26307.1 - 0.014 15.5 0.6 0.31 11.1 0.1 3.2 4 0 0 4 4 4 0 YqzH-like protein HBS1_N PF08938.10 VBB26307.1 - 0.039 14.3 0.1 0.039 14.3 0.1 2.3 3 0 0 3 3 3 0 HBS1 N-terminus EcoR124_C PF12008.8 VBB26307.1 - 1.4 8.5 6.7 0.47 10.1 0.5 2.4 2 1 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal KH_1 PF00013.29 VBB26308.1 - 1.4e-45 153.0 15.3 2.6e-19 68.8 2.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 VBB26308.1 - 6.9e-15 54.6 8.1 3.8e-06 26.6 0.2 3.3 2 1 1 3 3 3 3 KH domain KH_5 PF13184.6 VBB26308.1 - 1.9e-10 40.7 4.9 0.02 15.0 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 VBB26308.1 - 6.4e-08 32.4 6.2 0.0049 16.7 0.2 3.6 4 0 0 4 4 4 2 KH domain MOEP19 PF16005.5 VBB26308.1 - 0.00086 19.3 0.1 0.049 13.6 0.0 2.7 3 0 0 3 3 3 1 KH-like RNA-binding domain Citrate_bind PF16114.5 VBB26308.1 - 0.037 13.5 0.0 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding RuvC PF02075.17 VBB26308.1 - 0.067 13.1 0.6 0.14 12.1 0.6 1.5 1 1 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC KRBA1 PF15287.6 VBB26308.1 - 0.13 12.0 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 KRBA1 family repeat LCAT PF02450.15 VBB26309.1 - 3.4e-86 289.9 1.8 9.6e-85 285.1 1.8 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 VBB26309.1 - 0.0029 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 VBB26309.1 - 0.008 15.9 0.1 1.6 8.3 0.2 2.5 2 1 0 2 2 2 2 PGAP1-like protein DUF915 PF06028.11 VBB26309.1 - 0.015 14.7 0.3 6.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 VBB26309.1 - 0.016 15.8 0.0 0.038 14.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 VBB26309.1 - 0.036 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 VBB26309.1 - 0.052 13.2 0.2 0.8 9.3 0.2 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_2 PF01674.18 VBB26309.1 - 0.16 11.5 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) DUF2428 PF10350.9 VBB26310.1 - 1.1e-58 198.6 0.5 3.5e-58 197.0 0.5 1.9 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 VBB26310.1 - 0.11 12.8 6.1 15 6.1 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 VBB26310.1 - 0.14 12.5 0.1 0.94 9.9 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats DHFR_1 PF00186.19 VBB26311.1 - 1.8e-19 70.0 1.5 2.9e-16 59.6 1.5 2.8 1 1 0 1 1 1 1 Dihydrofolate reductase CBM_21 PF03370.13 VBB26313.1 - 6.3e-10 39.2 0.8 1.1e-09 38.5 0.2 1.7 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) FoP_duplication PF13865.6 VBB26314.1 - 6.2e-07 29.9 0.0 9.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Apt1 PF10351.9 VBB26315.1 - 0.01 14.8 5.4 0.011 14.6 5.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 VBB26315.1 - 2.9 6.4 12.4 3.6 6.0 12.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF5102 PF17104.5 VBB26315.1 - 4.1 7.3 8.5 6.6 6.7 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Sod_Fe_C PF02777.18 VBB26317.1 - 2e-33 114.6 0.0 3.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 VBB26317.1 - 7.4e-29 100.1 0.3 1.2e-28 99.4 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain LamB_YcsF PF03746.16 VBB26317.1 - 0.098 12.3 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 LamB/YcsF family TH1 PF04858.13 VBB26318.1 - 2e-150 502.2 1.3 2.3e-150 502.0 1.3 1.0 1 0 0 1 1 1 1 TH1 protein UMPH-1 PF05822.12 VBB26319.1 - 1.8e-84 283.1 0.3 2.4e-84 282.7 0.3 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) FHA PF00498.26 VBB26319.1 - 5.9e-14 52.2 0.0 1.5e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain HAD PF12710.7 VBB26319.1 - 1.4e-05 25.6 0.0 3.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Yop-YscD_cpl PF16697.5 VBB26319.1 - 4.2e-05 23.8 0.0 0.00016 21.9 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain UMPH-1 PF05822.12 VBB26320.1 - 6.9e-62 209.2 0.4 1.1e-61 208.5 0.4 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) zf-CCCH PF00642.24 VBB26320.1 - 3.8e-10 39.4 14.1 2.3e-05 24.2 1.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 VBB26320.1 - 1.9e-05 24.4 0.2 6.3e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 VBB26320.1 - 2e-05 24.5 15.6 0.017 15.2 4.7 2.8 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 VBB26320.1 - 0.00016 22.3 2.5 0.14 12.8 0.1 2.4 2 0 0 2 2 2 2 Torus domain HAD PF12710.7 VBB26320.1 - 0.00078 19.9 0.2 0.0026 18.2 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3083 PF11281.8 VBB26320.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3083) Nup35_RRM_2 PF14605.6 VBB26320.1 - 0.15 12.1 0.1 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 VBB26320.1 - 0.66 10.2 3.9 11 6.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family PDZ_6 PF17820.1 VBB26321.1 - 2.5e-09 36.9 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB26321.1 - 0.00021 21.6 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB26321.1 - 0.0072 16.6 0.0 0.0095 16.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Alba PF01918.21 VBB26322.1 - 7.6e-15 54.5 0.4 1.3e-14 53.7 0.4 1.4 1 0 0 1 1 1 1 Alba NTP_transf_5 PF14907.6 VBB26322.1 - 0.22 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase DUF2451 PF10474.9 VBB26323.1 - 1.1e-66 225.0 1.7 1.1e-66 225.0 1.7 2.1 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 VBB26323.1 - 5.6e-66 222.8 11.9 5.6e-66 222.8 11.9 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 VBB26323.1 - 0.03 14.5 1.8 0.072 13.3 0.6 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 WXG100 PF06013.12 VBB26323.1 - 0.05 13.8 0.7 6.1 7.1 0.0 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG KxDL PF10241.9 VBB26323.1 - 0.3 11.4 1.8 0.77 10.1 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein K-box PF01486.17 VBB26323.1 - 0.73 10.0 5.2 0.39 10.9 2.5 2.0 2 0 0 2 2 1 0 K-box region DUF16 PF01519.16 VBB26323.1 - 0.9 10.1 3.2 1.3 9.6 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 PhoU PF01895.19 VBB26323.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.7 3 1 0 3 3 3 0 PhoU domain NPV_P10 PF05531.12 VBB26323.1 - 3.7 8.1 5.8 3.6 8.1 1.3 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 VBB26323.1 - 5 6.9 8.7 2 8.2 2.8 3.2 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF4806 PF16064.5 VBB26323.1 - 8.9 6.7 6.5 1.9 8.8 0.6 3.0 4 0 0 4 4 2 0 Domain of unknown function (DUF4806) RAI16-like PF10257.9 VBB26324.1 - 2.2e-54 184.7 6.3 3.4e-54 184.1 6.3 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Synaptobrevin PF00957.21 VBB26324.1 - 0.057 13.2 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Synaptobrevin FXa_inhibition PF14670.6 VBB26325.1 - 4.2e-49 164.5 110.8 4.8e-11 42.8 7.8 7.6 7 0 0 7 7 7 6 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB26325.1 - 3.1e-30 103.7 61.4 1.3e-06 28.2 2.3 8.2 8 0 0 8 8 8 7 Complement Clr-like EGF-like EGF_CA PF07645.15 VBB26325.1 - 1.4e-22 79.6 97.7 1.1e-09 38.3 5.5 8.2 7 1 0 7 7 7 6 Calcium-binding EGF domain EMI PF07546.13 VBB26325.1 - 1.8e-10 41.4 11.7 1.8e-10 41.4 11.7 4.3 4 3 0 4 4 4 1 EMI domain EGF PF00008.27 VBB26325.1 - 4.8e-09 36.4 94.7 0.0012 19.1 5.4 8.8 9 1 0 9 9 9 5 EGF-like domain EGF_3 PF12947.7 VBB26325.1 - 0.00094 19.3 95.3 0.19 11.9 3.5 8.4 7 1 0 7 7 7 6 EGF domain hEGF PF12661.7 VBB26325.1 - 0.001 19.6 3.7 0.001 19.6 3.7 9.4 9 1 0 9 9 9 4 Human growth factor-like EGF Ras PF00071.22 VBB26326.1 - 3.9e-40 137.1 0.4 1.7e-38 131.8 0.4 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB26326.1 - 5.6e-15 55.6 0.0 3.2e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 VBB26326.1 - 8.1e-05 22.6 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 VBB26326.1 - 0.026 14.1 0.1 0.3 10.6 0.0 2.6 2 1 1 3 3 3 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 VBB26326.1 - 0.031 14.4 0.2 0.11 12.6 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 VBB26326.1 - 0.052 13.3 0.4 3.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 VBB26326.1 - 0.057 13.8 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF1232 PF06803.12 VBB26327.1 - 4.1e-08 32.9 8.2 7.7e-08 32.0 8.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) zf-RING_UBOX PF13445.6 VBB26327.1 - 4.1e-07 29.9 5.3 4.1e-07 29.9 5.3 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 VBB26327.1 - 5.4e-07 29.4 6.7 5.4e-07 29.4 6.7 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB26327.1 - 6.3e-07 29.2 9.7 6.3e-07 29.2 9.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB26327.1 - 5.2e-05 23.0 4.4 5.2e-05 23.0 4.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB26327.1 - 0.00028 21.1 10.1 0.00028 21.1 10.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 VBB26327.1 - 0.00064 19.8 12.7 0.00064 19.8 12.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 VBB26327.1 - 0.00074 19.4 9.9 0.00074 19.4 9.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 VBB26327.1 - 0.0022 17.8 7.7 0.0022 17.8 7.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 TerY_C PF15616.6 VBB26327.1 - 0.043 13.9 2.7 0.073 13.2 2.7 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-ANAPC11 PF12861.7 VBB26327.1 - 0.11 12.6 2.3 0.21 11.7 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FdhE PF04216.12 VBB26327.1 - 0.25 11.2 1.6 0.34 10.7 1.6 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2070 PF09843.9 VBB26327.1 - 1.5 7.0 5.2 0.71 8.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF726 PF05277.12 VBB26328.1 - 4.2e-116 387.6 5.8 4.2e-116 387.6 5.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF726) DnaJ PF00226.31 VBB26328.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 VBB26328.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Pam16 JAB PF01398.21 VBB26329.1 - 8.3e-18 64.5 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 VBB26329.1 - 2.2e-08 34.5 0.0 3.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Ldh_1_N PF00056.23 VBB26330.1 - 3.9e-43 146.9 0.2 6.1e-43 146.3 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 VBB26330.1 - 1.7e-21 76.9 0.3 4.5e-21 75.5 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Peptidase_M13_N PF05649.13 VBB26332.1 - 2.4e-93 313.8 7.3 2.4e-93 313.8 7.3 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 VBB26332.1 - 1.5e-70 237.0 0.0 3.1e-70 236.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 Acyl_transf_3 PF01757.22 VBB26332.1 - 1.7e-22 79.9 47.5 3.2e-22 79.1 47.5 1.3 1 0 0 1 1 1 1 Acyltransferase family LRR_4 PF12799.7 VBB26332.1 - 0.13 12.7 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Dymeclin PF09742.9 VBB26333.1 - 2e-137 459.3 15.1 6.3e-137 457.6 15.1 1.6 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 VBB26333.1 - 3.4e-10 38.7 13.4 5.6e-07 28.1 2.7 3.6 3 1 1 4 4 4 3 High-temperature-induced dauer-formation protein RTP1_C1 PF10363.9 VBB26333.1 - 0.1 12.8 0.8 2.2 8.5 0.1 2.7 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 adh_short PF00106.25 VBB26334.1 - 8e-29 100.5 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB26334.1 - 3.8e-11 43.0 0.0 5.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB26334.1 - 4.6e-06 26.7 0.0 1.4e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 VBB26334.1 - 0.00014 21.2 0.0 0.0002 20.6 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein FERM_C PF09380.10 VBB26335.1 - 1.5e-19 70.2 0.1 2.9e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 VBB26335.1 - 7e-19 68.4 0.1 1.4e-18 67.4 0.1 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 VBB26335.1 - 4.4e-12 45.8 0.0 1.2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 VBB26335.1 - 2.2e-10 40.4 8.1 2.2e-10 40.4 8.1 3.1 3 0 0 3 3 3 1 FERM adjacent (FA) Ufm1 PF03671.14 VBB26336.1 - 1.2e-42 143.9 0.2 1.5e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Rhomboid PF01694.22 VBB26337.1 - 5.3e-40 136.9 10.0 5.3e-40 136.9 10.0 1.7 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.6 VBB26337.1 - 6e-13 49.0 0.3 1.1e-12 48.2 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 VBB26337.1 - 3.9e-10 38.5 0.1 0.00059 19.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 VBB26337.1 - 7.6e-09 34.8 0.3 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 VBB26337.1 - 3.7e-08 33.1 0.6 3.7e-07 29.9 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 VBB26337.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 VBB26337.1 - 0.0018 17.7 0.2 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 EF hand TerB PF05099.13 VBB26337.1 - 0.0067 16.4 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF5345 PF17280.2 VBB26337.1 - 0.53 10.3 3.1 5.2 7.1 0.6 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF21 PF01595.20 VBB26338.1 - 5.3e-34 117.4 0.5 8.9e-34 116.7 0.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Lectin_C PF00059.21 VBB26338.1 - 0.00022 21.9 0.4 0.42 11.4 0.1 2.7 2 0 0 2 2 2 2 Lectin C-type domain zf-C3HC4 PF00097.25 VBB26338.1 - 0.00061 19.6 31.9 0.0021 17.9 3.1 3.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Tfb2_C PF18307.1 VBB26338.1 - 0.063 13.7 0.0 4.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain DUF5316 PF17247.2 VBB26338.1 - 0.11 12.6 0.2 0.41 10.7 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5316) zf-C3HC4_2 PF13923.6 VBB26338.1 - 0.44 10.4 28.3 0.23 11.3 3.5 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB26338.1 - 1.7 9.1 35.7 0.59 10.5 4.8 3.7 3 0 0 3 3 3 0 Ring finger domain Bystin PF05291.11 VBB26339.1 - 7.2e-133 442.4 3.2 1.2e-132 441.6 3.2 1.3 1 0 0 1 1 1 1 Bystin Ribosomal_L3 PF00297.22 VBB26339.1 - 8.9e-14 51.2 0.9 3.1e-12 46.2 0.7 2.8 1 1 1 2 2 2 2 Ribosomal protein L3 SPRY PF00622.28 VBB26340.1 - 4.1e-16 59.2 0.0 6.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 VBB26340.1 - 7.1e-11 41.8 2.1 1.8e-10 40.6 2.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB26340.1 - 1.6e-07 31.0 1.6 1.9e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 F-box domain Ribosomal_L11_N PF03946.14 VBB26342.1 - 2.3e-22 78.6 1.2 3.3e-22 78.1 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 VBB26342.1 - 5.5e-18 65.2 0.2 5.5e-18 65.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Cadherin PF00028.17 VBB26343.1 - 1.7e-294 951.5 53.7 1.4e-16 60.7 0.0 31.3 31 0 0 31 31 31 28 Cadherin domain Cadherin_2 PF08266.12 VBB26343.1 - 3.3e-21 74.9 1.2 0.15 11.9 0.0 13.4 16 0 0 16 16 16 5 Cadherin-like RET_CLD1 PF17756.1 VBB26343.1 - 9e-14 51.8 0.2 0.002 18.4 0.0 10.4 11 1 0 11 11 11 1 RET Cadherin like domain 1 EGF PF00008.27 VBB26343.1 - 6.7e-13 48.7 66.7 3.1e-05 24.2 8.0 5.9 5 1 0 5 5 5 4 EGF-like domain Cadherin_pro PF08758.11 VBB26343.1 - 9.7e-13 48.1 1.7 0.13 12.5 0.0 12.2 16 0 0 16 16 16 2 Cadherin prodomain like Laminin_G_2 PF02210.24 VBB26343.1 - 3.1e-12 47.2 0.0 1.4e-11 45.1 0.0 2.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 VBB26343.1 - 3.3e-08 33.8 0.0 2.5e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 VBB26343.1 - 2.6e-07 30.6 43.7 0.17 11.9 0.1 14.5 15 0 0 15 15 15 3 Cadherin-like PKD PF00801.20 VBB26343.1 - 0.066 13.1 0.0 22 5.0 0.0 3.9 3 0 0 3 3 3 0 PKD domain DUF824 PF05688.11 VBB26343.1 - 0.15 11.9 0.0 0.7 9.8 0.0 2.2 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Sigma_reg_N PF13800.6 VBB26343.1 - 0.19 12.0 0.9 0.54 10.6 0.6 1.9 2 0 0 2 2 1 0 Sigma factor regulator N-terminal MRP-63 PF14978.6 VBB26344.1 - 0.00036 21.1 10.1 0.0017 18.9 6.0 2.9 2 1 0 2 2 2 1 Mitochondrial ribosome protein 63 HMG_box PF00505.19 VBB26345.1 - 3.9e-18 65.6 6.2 7.8e-18 64.7 6.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB26345.1 - 8.8e-11 42.2 3.9 2e-10 41.1 3.9 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 VBB26345.1 - 0.025 13.9 0.1 0.053 12.8 0.1 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box CHDNT PF08073.12 VBB26345.1 - 0.093 12.7 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain Protamine_like PF06382.11 VBB26345.1 - 0.1 12.8 1.7 0.2 11.8 1.4 1.6 1 1 0 1 1 1 0 Protamine and protamine like BAR PF03114.18 VBB26346.1 - 8e-05 22.4 7.6 8e-05 22.4 7.6 1.9 2 0 0 2 2 2 1 BAR domain BNIP3 PF06553.12 VBB26346.1 - 0.084 12.5 9.3 0.35 10.5 4.6 2.9 3 0 0 3 3 3 0 BNIP3 DUF5600 PF18150.1 VBB26347.1 - 1.9e-13 50.9 1.2 5.4e-13 49.5 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 VBB26347.1 - 4e-09 36.6 0.0 1.3e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 VBB26347.1 - 4.6e-09 36.5 0.0 4.6e-09 36.5 0.0 3.5 2 2 0 2 2 2 1 Dynamin family EHD_N PF16880.5 VBB26347.1 - 4.8e-08 32.8 0.2 1.1e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Roc PF08477.13 VBB26347.1 - 0.0094 16.2 0.1 0.33 11.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 VBB26347.1 - 0.016 14.7 0.0 5.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 VBB26347.1 - 0.04 13.3 0.5 0.16 11.3 0.5 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Neur_chan_memb PF02932.16 VBB26347.1 - 2.3 8.2 10.5 3.8 7.5 10.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.16 VBB26350.1 - 3.1e-193 626.5 11.0 4.3e-18 65.2 0.0 20.1 19 0 0 19 19 19 19 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB26350.1 - 4.1e-144 469.5 8.7 7.1e-12 45.8 0.0 20.6 20 0 0 20 20 20 19 Immunoglobulin domain Ig_2 PF13895.6 VBB26350.1 - 3.8e-75 248.2 17.4 1.8e-08 34.6 0.0 18.6 18 0 0 18 18 18 12 Immunoglobulin domain ig PF00047.25 VBB26350.1 - 6e-62 205.8 20.6 3.4e-08 33.5 0.4 15.5 16 0 0 16 16 16 11 Immunoglobulin domain V-set PF07686.17 VBB26350.1 - 8.9e-16 58.0 31.7 0.037 14.2 0.1 15.2 12 6 1 13 13 13 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB26350.1 - 6.9e-13 48.5 3.8 1.7 8.7 0.0 10.3 11 0 0 11 11 11 3 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 VBB26350.1 - 3.8e-05 23.9 7.0 1.3 9.3 0.0 7.1 8 0 0 8 8 8 2 Natural killer cell receptor 2B4 Adeno_E3_CR1 PF02440.15 VBB26350.1 - 7.9e-05 22.4 10.9 0.028 14.2 0.2 5.0 5 0 0 5 5 5 2 Adenovirus E3 region protein CR1 C1-set PF07654.15 VBB26350.1 - 7.4 7.0 30.2 0.47 10.9 1.0 9.8 12 0 0 12 12 12 0 Immunoglobulin C1-set domain Gtr1_RagA PF04670.12 VBB26351.1 - 2.5e-93 311.7 0.7 3.9e-93 311.1 0.7 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ima1_N PF09779.9 VBB26351.1 - 6.7e-26 91.8 12.2 1.5e-25 90.6 12.2 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain Arf PF00025.21 VBB26351.1 - 6e-07 29.1 0.1 3.4e-06 26.6 0.0 2.0 1 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 VBB26351.1 - 6.8e-07 29.5 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB26351.1 - 6.5e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 VBB26351.1 - 4.1e-05 23.6 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 VBB26351.1 - 0.0083 15.3 0.3 0.039 13.1 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) DUF2448 PF10476.9 VBB26351.1 - 0.08 12.8 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) PduV-EutP PF10662.9 VBB26351.1 - 0.11 12.2 0.1 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 VBB26351.1 - 0.14 12.7 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter zinc_ribbon_6 PF14599.6 VBB26351.1 - 1.9 8.6 7.1 48 4.1 0.0 2.9 2 0 0 2 2 2 0 Zinc-ribbon SAPS PF04499.15 VBB26352.1 - 4.5e-19 68.6 0.8 4.5e-19 68.6 0.8 3.3 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein Ovate PF04844.13 VBB26352.1 - 0.06 13.4 0.0 0.28 11.2 0.0 2.1 1 0 0 1 1 1 0 Transcriptional repressor, ovate Sas10 PF09368.10 VBB26353.1 - 8.7e-21 74.2 11.7 2.1e-20 73.0 11.7 1.6 1 0 0 1 1 1 1 Sas10 C-terminal domain Ank_2 PF12796.7 VBB26354.1 - 4e-40 136.3 8.7 7.9e-19 68.0 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB26354.1 - 2.6e-36 123.5 1.2 2.9e-15 56.4 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB26354.1 - 2.2e-29 101.1 11.1 1.5e-11 44.3 0.2 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 VBB26354.1 - 2.9e-28 97.1 7.7 1e-06 28.9 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 VBB26354.1 - 1.8e-27 92.4 1.9 6.6e-06 26.1 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat PRKG1_interact PF15898.5 VBB26354.1 - 5.4e-23 81.8 11.3 5.4e-23 81.8 11.3 4.7 4 2 0 4 4 4 1 cGMP-dependent protein kinase interacting domain Smg8_Smg9 PF10220.9 VBB26355.1 - 5.1e-162 541.3 6.3 3.1e-160 535.4 6.3 2.1 1 1 0 1 1 1 1 Smg8_Smg9 Ion_trans_2 PF07885.16 VBB26355.1 - 1.3e-29 101.9 20.7 6.5e-15 54.9 7.1 2.4 2 0 0 2 2 2 2 Ion channel fn3 PF00041.21 VBB26355.1 - 1.7e-14 53.9 0.1 1.7e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Ion_trans PF00520.31 VBB26355.1 - 6.9e-05 22.2 7.6 0.011 14.9 0.1 2.2 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 VBB26355.1 - 0.042 13.7 1.2 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel fn3 PF00041.21 VBB26357.1 - 1.2e-94 310.8 24.7 2.7e-12 46.9 0.1 11.8 11 0 0 11 11 11 11 Fibronectin type III domain VWA PF00092.28 VBB26357.1 - 1.4e-64 217.6 11.8 1.4e-20 74.3 0.1 5.4 5 0 0 5 5 5 5 von Willebrand factor type A domain Ig_3 PF13927.6 VBB26357.1 - 9.6e-38 128.7 18.0 3.5e-06 27.5 0.1 9.1 8 1 1 9 9 8 7 Immunoglobulin domain VWA_2 PF13519.6 VBB26357.1 - 2.7e-32 111.6 1.9 1.3e-09 38.7 0.0 5.1 5 0 0 5 5 5 4 von Willebrand factor type A domain I-set PF07679.16 VBB26357.1 - 2.9e-28 97.8 2.9 0.00076 19.5 0.0 9.6 8 1 0 8 8 8 5 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 VBB26357.1 - 4.2e-22 78.5 2.3 0.065 13.8 0.0 11.1 11 0 0 11 11 11 5 Purple acid Phosphatase, N-terminal domain ig PF00047.25 VBB26357.1 - 6.1e-22 77.6 0.1 9.2e-06 25.8 0.0 7.4 7 0 0 7 7 7 3 Immunoglobulin domain Ig_2 PF13895.6 VBB26357.1 - 2e-20 72.9 1.0 0.0014 18.9 0.0 7.5 7 0 0 7 7 7 3 Immunoglobulin domain FXa_inhibition PF14670.6 VBB26357.1 - 3.6e-14 52.8 54.5 8.8e-08 32.3 7.4 5.0 5 0 0 5 5 4 3 Coagulation Factor Xa inhibitory site C2-set_2 PF08205.12 VBB26357.1 - 1.8e-12 47.2 2.4 0.0096 16.0 0.0 6.9 7 0 0 7 7 7 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 VBB26357.1 - 7.5e-06 26.2 0.1 0.2 12.0 0.0 5.7 6 0 0 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III EGF_CA PF07645.15 VBB26357.1 - 0.00056 20.1 6.3 0.00056 20.1 6.3 4.3 4 0 0 4 4 1 1 Calcium-binding EGF domain Glyco_hydro_36C PF16874.5 VBB26357.1 - 0.0016 18.9 0.0 4 8.0 0.0 4.1 4 0 0 4 4 3 1 Glycosyl hydrolase family 36 C-terminal domain cEGF PF12662.7 VBB26357.1 - 0.0055 16.6 0.4 0.0055 16.6 0.4 6.2 5 0 0 5 5 5 1 Complement Clr-like EGF-like Ssl1 PF04056.14 VBB26357.1 - 0.19 11.5 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 Ssl1-like DUF2635 PF10948.8 VBB26357.1 - 0.69 9.7 9.4 2.1 8.2 0.0 6.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2635) DUF3591 PF12157.8 VBB26358.1 - 7.2e-149 496.2 0.0 1.2e-148 495.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 VBB26358.1 - 4.9e-36 122.7 5.0 2.1e-17 63.0 0.8 2.7 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.6 VBB26358.1 - 9.2e-05 22.2 1.4 0.00025 20.8 1.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Jnk-SapK_ap_N PF09744.9 VBB26359.1 - 2.1e-31 109.2 12.0 2.1e-31 109.2 12.0 3.2 1 1 2 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 VBB26359.1 - 5.8e-09 36.0 5.6 5.8e-09 36.0 5.6 3.0 3 0 0 3 3 3 1 Rab interacting lysosomal protein YabA PF06156.13 VBB26359.1 - 0.025 15.2 7.8 0.025 15.2 7.8 3.9 1 1 3 4 4 4 0 Initiation control protein YabA ADIP PF11559.8 VBB26359.1 - 0.12 12.5 29.9 0.09 12.9 12.4 2.4 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 VBB26359.1 - 0.17 12.2 0.1 0.17 12.2 0.1 5.2 4 1 1 5 5 5 0 TSC-22/dip/bun family CP12 PF02672.15 VBB26359.1 - 0.26 12.0 9.3 12 6.8 0.1 3.6 2 1 1 3 3 3 0 CP12 domain HAUS-augmin3 PF14932.6 VBB26359.1 - 0.85 9.1 31.1 0.088 12.4 13.1 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GIT_CC PF16559.5 VBB26359.1 - 1 9.3 24.1 0.6 10.0 0.2 4.6 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 VBB26359.1 - 1.9 8.8 5.9 0.91 9.8 0.7 2.9 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UCH PF00443.29 VBB26359.1 - 2.8 7.4 16.9 96 2.3 17.0 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF935 PF06074.12 VBB26360.1 - 0.062 12.0 0.1 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) PCMT PF01135.19 VBB26361.1 - 3.8e-77 258.8 0.0 4.5e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 VBB26361.1 - 4.6e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 VBB26361.1 - 2.4e-05 23.9 0.1 3.5e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 VBB26361.1 - 0.00049 20.1 0.1 0.0007 19.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB26361.1 - 0.00054 20.6 0.0 0.0012 19.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 VBB26361.1 - 0.0009 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 VBB26361.1 - 0.0016 18.3 0.0 0.0071 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB26361.1 - 0.0031 18.1 0.1 0.0073 16.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB26361.1 - 0.0035 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 VBB26361.1 - 0.01 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.17 VBB26361.1 - 0.013 14.6 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Fibrillarin GCD14 PF08704.10 VBB26361.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit EF-hand_1 PF00036.32 VBB26361.1 - 0.015 14.8 0.1 0.047 13.3 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 VBB26361.1 - 0.016 15.1 0.2 0.086 12.8 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain Methyltransf_3 PF01596.17 VBB26361.1 - 0.022 13.9 0.1 0.071 12.3 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_16 PF10294.9 VBB26361.1 - 0.036 13.8 0.2 0.057 13.1 0.2 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltr_RsmB-F PF01189.17 VBB26361.1 - 0.036 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 VBB26361.1 - 0.038 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 VBB26361.1 - 0.04 13.8 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 VBB26361.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.19 VBB26361.1 - 0.083 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase EF-hand_5 PF13202.6 VBB26361.1 - 0.089 12.3 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 EF hand Methyltransf_9 PF08003.11 VBB26361.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 VBB26361.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 VBB26362.1 - 6.9e-71 238.3 0.0 8.3e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 VBB26362.1 - 3e-07 30.3 0.0 6.2e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 VBB26362.1 - 8.5e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 VBB26362.1 - 8.9e-05 22.5 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB26362.1 - 0.00037 21.1 0.0 0.00065 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB26362.1 - 0.00068 20.2 0.0 0.0014 19.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB26362.1 - 0.0029 17.2 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 VBB26362.1 - 0.005 16.0 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 VBB26362.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 VBB26362.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 VBB26362.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 VBB26362.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 VBB26362.1 - 0.051 14.6 0.0 0.095 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 VBB26362.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 VBB26362.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 VBB26362.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 2 0 0 2 2 2 0 DNA methylase DOT1 PF08123.13 VBB26362.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 CUB PF00431.20 VBB26363.1 - 0 1024.7 46.2 5.6e-24 84.6 0.0 28.8 26 3 0 26 26 26 26 CUB domain EGF PF00008.27 VBB26363.1 - 2.3e-15 56.5 103.6 5e-07 29.9 4.9 9.5 9 0 0 9 9 9 6 EGF-like domain EGF_CA PF07645.15 VBB26363.1 - 2.1e-13 50.2 98.1 1.4e-08 34.8 4.8 9.5 4 3 4 8 8 8 4 Calcium-binding EGF domain CUB_2 PF02408.20 VBB26363.1 - 2.9e-10 40.0 24.9 0.39 10.5 0.0 13.6 14 0 0 14 14 14 4 CUB-like domain hEGF PF12661.7 VBB26363.1 - 5.3e-08 33.2 71.6 7.1e-05 23.3 1.3 10.2 9 0 0 9 9 9 4 Human growth factor-like EGF EGF_3 PF12947.7 VBB26363.1 - 8.1e-07 29.1 95.6 0.014 15.6 2.9 9.2 8 0 0 8 8 8 5 EGF domain cEGF PF12662.7 VBB26363.1 - 2e-06 27.6 54.4 0.0019 18.1 0.0 8.6 8 0 0 8 8 8 4 Complement Clr-like EGF-like EGF_2 PF07974.13 VBB26363.1 - 0.0041 17.5 7.3 0.0041 17.5 7.3 7.5 7 0 0 7 7 7 3 EGF-like domain ATP-synt_ab PF00006.25 VBB26364.1 - 9.7e-109 362.0 0.0 1.4e-108 361.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 VBB26364.1 - 5.8e-35 119.8 0.0 1.2e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 VBB26364.1 - 3.6e-14 53.0 0.9 9.2e-14 51.7 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ank_2 PF12796.7 VBB26366.1 - 3.3e-09 37.2 0.0 7.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB26366.1 - 1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB26366.1 - 4.4e-08 33.2 0.0 6.9e-06 26.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 VBB26366.1 - 1.1e-06 28.4 0.0 1.1e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 VBB26366.1 - 6.1e-06 26.7 0.0 1.8e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ribosomal_L2_C PF03947.18 VBB26366.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain GTP_cyclohydroI PF01227.22 VBB26367.1 - 1.4e-72 242.8 0.6 1.7e-72 242.6 0.6 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 VBB26367.1 - 0.0012 18.9 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 QueF-like protein NCD1 PF04904.13 VBB26367.1 - 0.059 13.4 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) NPA PF16469.5 VBB26368.1 - 1.1e-171 562.1 76.9 1.7e-27 96.4 7.7 8.1 8 0 0 8 8 8 8 Nematode polyprotein allergen ABA-1 Laminin_EGF PF00053.24 VBB26368.1 - 4.5e-10 39.5 49.8 1.5e-06 28.2 17.3 3.6 3 0 0 3 3 3 2 Laminin EGF domain Band_7_1 PF13421.6 VBB26368.1 - 0.088 12.5 9.8 6.3 6.4 0.3 4.2 4 0 0 4 4 4 0 SPFH domain-Band 7 family ApoB100_C PF12491.8 VBB26368.1 - 0.83 9.7 3.6 36 4.4 0.1 4.2 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal F-box PF00646.33 VBB26369.1 - 0.023 14.6 0.6 0.09 12.7 0.0 2.2 2 0 0 2 2 2 0 F-box domain Ion_trans_2 PF07885.16 VBB26370.1 - 3.4e-30 103.8 23.8 6.5e-16 58.1 0.3 3.7 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB26370.1 - 2.5e-05 23.6 5.6 0.028 13.7 0.0 2.6 2 0 0 2 2 2 2 Ion transport protein Surp PF01805.20 VBB26371.1 - 1.7e-38 130.4 9.2 2e-19 69.3 0.9 2.9 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 VBB26371.1 - 1.8e-33 116.3 11.6 8.9e-32 110.7 4.4 2.3 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 VBB26371.1 - 1.9e-12 46.8 0.0 9.2e-12 44.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 VBB26371.1 - 0.0098 15.7 0.0 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like INTS5_C PF14838.6 VBB26371.1 - 0.22 10.1 0.2 0.3 9.6 0.2 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Fis1_TPR_C PF14853.6 VBB26376.1 - 1.4e-21 76.3 0.7 3.1e-21 75.2 0.7 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 VBB26376.1 - 1.3e-07 31.1 0.1 2.7e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.6 VBB26376.1 - 0.00086 19.9 0.1 0.0017 19.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB26376.1 - 0.047 13.8 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 VBB26376.1 - 0.07 14.0 0.9 1.2 10.1 0.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB26376.1 - 0.1 12.8 1.3 0.28 11.5 1.2 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 VBB26376.1 - 0.14 12.0 0.3 0.37 10.7 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB26376.1 - 0.4 11.2 3.3 0.2 12.2 0.7 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat 7tm_1 PF00001.21 VBB26378.1 - 1.3e-16 60.7 8.7 1.3e-16 60.7 8.7 1.8 1 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Thioredoxin_2 PF13098.6 VBB26378.1 - 0.2 12.1 0.4 1 9.8 0.3 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Zona_pellucida PF00100.23 VBB26379.1 - 4.1e-16 59.6 5.4 6e-16 59.0 5.4 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Acyltransferase PF01553.21 VBB26380.1 - 7.3e-20 71.0 0.0 9.3e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF3275 PF11679.8 VBB26380.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Collagen PF01391.18 VBB26381.1 - 1.3e-23 82.5 90.2 1e-09 38.0 32.5 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Folate_carrier PF01770.18 VBB26382.1 - 1.3e-106 356.8 37.1 8.8e-55 186.1 8.1 2.1 1 1 1 2 2 2 2 Reduced folate carrier CbtB PF09489.10 VBB26382.1 - 0.21 11.7 3.8 22 5.2 0.1 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Somatomedin_B PF01033.17 VBB26384.1 - 5.8e-07 29.8 6.5 5.8e-07 29.8 6.5 3.7 4 0 0 4 4 4 1 Somatomedin B domain TSP_1 PF00090.19 VBB26384.1 - 0.00078 19.6 6.3 0.0027 17.9 6.3 2.0 1 0 0 1 1 1 1 Thrombospondin type 1 domain POLO_box PF00659.18 VBB26384.1 - 0.04 14.1 0.1 0.59 10.4 0.0 2.7 2 0 0 2 2 2 0 POLO box duplicated region HLH PF00010.26 VBB26385.1 - 3.5e-15 55.7 0.7 3.5e-15 55.7 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain zf-H2C2_2 PF13465.6 VBB26385.1 - 3.4e-13 49.4 59.3 0.0071 16.7 0.1 11.5 11 0 0 11 11 11 7 Zinc-finger double domain zf-Di19 PF05605.12 VBB26385.1 - 0.00016 21.9 78.0 0.011 16.0 1.2 8.7 7 2 2 9 9 9 6 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 VBB26385.1 - 0.004 16.9 0.3 0.004 16.9 0.3 9.1 12 1 0 12 12 12 2 C2H2-type zinc-finger domain PHZA_PHZB PF03284.13 VBB26385.1 - 0.024 14.3 2.6 2.5 7.7 0.0 3.3 3 0 0 3 3 3 0 Phenazine biosynthesis protein A/B zf-BED PF02892.15 VBB26385.1 - 0.22 11.6 0.0 0.22 11.6 0.0 8.2 7 4 1 8 8 8 0 BED zinc finger zf-ACC PF17848.1 VBB26385.1 - 2.8 8.1 6.8 19 5.4 0.4 4.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain GatB_N PF02934.15 VBB26386.1 - 1.7e-95 319.5 0.0 2.7e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 VBB26386.1 - 2.1e-11 43.9 0.7 3.3e-11 43.3 0.7 1.4 1 0 0 1 1 1 1 GatB domain DUF2321 PF10083.9 VBB26386.1 - 0.2 11.3 4.8 2 8.0 1.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) COMPASS-Shg1 PF05205.12 VBB26386.1 - 1 10.1 6.0 1.8 9.3 3.2 2.2 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 FtsJ PF01728.19 VBB26387.1 - 7e-69 231.5 0.1 8.7e-69 231.2 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Glyco_trans_2_3 PF13632.6 VBB26388.1 - 1.2e-38 133.0 3.0 1.2e-38 133.0 3.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 VBB26388.1 - 6.8e-08 32.7 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF572 PF04502.13 VBB26389.1 - 9.6e-86 288.4 12.9 1.1e-85 288.2 12.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) MCR PF18509.1 VBB26389.1 - 0.19 11.4 0.4 0.4 10.3 0.4 1.6 1 0 0 1 1 1 0 Magnetochrome domain Cytochrome_C7 PF14522.6 VBB26389.1 - 0.2 11.7 1.3 0.66 10.0 1.3 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-FCS PF06467.14 VBB26389.1 - 0.97 9.4 3.5 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TPR_8 PF13181.6 VBB26390.1 - 2.6e-14 52.2 24.4 0.1 12.8 0.6 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 VBB26390.1 - 1.1e-13 50.4 30.5 0.0021 17.8 0.7 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 VBB26390.1 - 5.4e-12 44.9 26.8 0.17 12.1 0.3 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 VBB26390.1 - 1.1e-11 44.9 9.0 9.5e-06 25.8 0.4 5.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB26390.1 - 5.2e-09 36.6 7.7 0.0047 17.5 0.1 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB26390.1 - 1.1e-06 29.0 3.7 5.4 8.1 0.2 6.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB26390.1 - 2.7e-06 27.3 15.3 1.4 9.5 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB26390.1 - 5e-05 22.9 12.5 0.0006 19.4 0.3 4.6 5 1 1 6 6 6 2 TPR repeat TPR_19 PF14559.6 VBB26390.1 - 6.5e-05 23.4 8.5 0.18 12.3 0.1 6.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB26390.1 - 0.0001 22.1 5.3 8.9 6.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC8 PF04049.13 VBB26390.1 - 0.0057 16.7 7.8 0.046 13.8 7.8 2.4 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_10 PF13374.6 VBB26390.1 - 0.011 15.5 2.9 10 6.2 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.9 VBB26390.1 - 0.038 13.7 0.4 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 VBB26390.1 - 0.079 12.3 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 VBB26390.1 - 0.16 12.6 12.7 0.88 10.3 0.3 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB26390.1 - 1.1 9.5 23.5 12 6.2 0.3 5.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_transf_7C PF02709.14 VBB26391.1 - 3.9e-22 77.7 0.0 7.9e-22 76.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 VBB26391.1 - 1.2e-20 73.5 0.3 2.2e-20 72.6 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 F-box PF00646.33 VBB26392.1 - 4.5e-07 29.6 0.9 4.5e-07 29.6 0.9 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 VBB26392.1 - 0.0004 20.2 1.4 0.0018 18.1 0.4 2.4 2 0 0 2 2 2 1 F-box-like ATP-synt_C PF00137.21 VBB26393.1 - 8.9e-31 106.0 34.5 7.4e-19 67.9 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C I-EGF_1 PF18372.1 VBB26393.1 - 0.03 14.4 2.7 0.049 13.7 2.7 1.4 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 ATP-synt_C PF00137.21 VBB26394.1 - 1.4e-34 118.2 34.7 2.7e-22 78.9 13.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 VBB26394.1 - 1.6 8.7 7.7 0.46 10.4 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) PRA1 PF03208.19 VBB26396.1 - 3.3e-29 101.4 11.3 3.9e-29 101.1 11.3 1.0 1 0 0 1 1 1 1 PRA1 family protein ABC2_membrane_3 PF12698.7 VBB26396.1 - 1.3 8.0 16.2 2.2 7.3 16.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DPM3 PF08285.11 VBB26396.1 - 1.8 8.8 6.1 2.6 8.3 5.6 1.6 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WD40 PF00400.32 VBB26397.1 - 1.9e-14 53.8 23.4 0.0054 17.5 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB26397.1 - 2.1e-05 24.7 11.2 0.0023 18.2 0.9 3.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pre-PUA PF17832.1 VBB26398.1 - 5.3e-22 78.3 0.1 8.2e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 VBB26398.1 - 3.7e-17 62.1 0.2 6e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 PUA domain APG6 PF04111.12 VBB26399.1 - 7.8e-59 198.6 0.0 1.3e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 VBB26399.1 - 3e-20 73.1 17.9 5.3e-20 72.3 17.9 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region OmpH PF03938.14 VBB26399.1 - 0.38 11.1 4.6 0.79 10.1 4.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 VBB26399.1 - 0.52 8.9 3.0 0.77 8.3 3.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Arf PF00025.21 VBB26400.1 - 5.6e-54 182.2 0.3 1.2e-53 181.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 VBB26400.1 - 4.7e-10 39.2 3.8 7.4e-08 31.9 0.0 3.3 2 1 1 3 3 3 2 G-protein alpha subunit Roc PF08477.13 VBB26400.1 - 2.2e-08 34.3 0.0 3.7e-07 30.4 0.0 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 VBB26400.1 - 3.2e-07 30.4 0.1 2.2e-06 27.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 VBB26400.1 - 1.1e-06 28.2 0.2 3.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 VBB26400.1 - 5.1e-05 22.9 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Ras family cobW PF02492.19 VBB26400.1 - 0.00063 19.4 1.2 0.21 11.2 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 VBB26400.1 - 0.0011 18.4 0.0 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Rootletin PF15035.6 VBB26400.1 - 0.073 13.1 12.1 0.12 12.4 12.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 VBB26400.1 - 3.3 7.8 14.1 5.9 6.9 14.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BAR_3_WASP_bdg PF10456.9 VBB26401.1 - 2.2e-70 236.8 0.8 3.5e-70 236.1 0.8 1.3 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 VBB26401.1 - 7.8e-21 74.2 0.1 2.4e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 VBB26401.1 - 9.5e-12 44.6 0.0 2.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB26401.1 - 9.9e-09 34.7 0.0 2.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB26401.1 - 4.2e-08 32.8 0.1 1.1e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 VBB26403.1 - 5.5e-36 122.8 10.5 4.4e-12 46.2 0.1 3.6 3 0 0 3 3 3 3 PDZ domain FERM_M PF00373.18 VBB26403.1 - 1.3e-24 86.9 1.3 2.8e-24 85.8 0.2 2.2 2 0 0 2 2 2 1 FERM central domain PDZ_6 PF17820.1 VBB26403.1 - 8e-19 67.2 3.1 9.9e-07 28.5 0.1 3.7 3 0 0 3 3 3 3 PDZ domain FERM_C PF09380.10 VBB26403.1 - 2.2e-10 40.8 0.5 4.9e-10 39.7 0.5 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PDZ_2 PF13180.6 VBB26403.1 - 4.4e-10 39.7 5.9 0.014 15.7 0.6 3.8 3 0 0 3 3 3 3 PDZ domain FERM_N PF09379.10 VBB26403.1 - 3.8e-08 33.1 0.0 2.9e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 FERM N-terminal domain Pkinase_Tyr PF07714.17 VBB26404.1 - 2.6e-83 279.3 0.0 3.8e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB26404.1 - 1.6e-45 155.6 0.0 2.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.28 VBB26404.1 - 0.00069 19.9 1.0 0.0032 17.8 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 VBB26404.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 VBB26404.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.21 VBB26405.1 - 2.7e-26 91.8 0.1 4.4e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase G-patch PF01585.23 VBB26406.1 - 7e-10 38.6 2.0 1.7e-09 37.4 2.0 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 VBB26406.1 - 2.5e-06 27.2 0.2 5.1e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 VBB26406.1 - 0.39 11.8 1.6 0.75 10.9 0.0 2.2 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein cNMP_binding PF00027.29 VBB26407.1 - 1.5e-14 53.8 0.0 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 VBB26407.1 - 1.9e-10 40.4 4.4 2.5e-10 40.0 4.4 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 VBB26407.1 - 6e-05 23.3 0.1 0.00015 22.0 0.1 1.8 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GvpK PF05121.12 VBB26407.1 - 0.018 15.1 0.1 0.053 13.6 0.1 1.8 1 0 0 1 1 1 0 Gas vesicle protein K FlaC_arch PF05377.11 VBB26407.1 - 0.047 14.1 0.2 0.4 11.1 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HMG_box PF00505.19 VBB26408.1 - 7.9e-27 93.5 3.8 7.9e-27 93.5 3.8 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB26408.1 - 3.6e-11 43.5 2.2 3.6e-11 43.5 2.2 2.2 2 0 0 2 2 2 1 HMG-box domain SOXp PF12336.8 VBB26408.1 - 0.00091 20.2 9.1 0.0013 19.8 4.3 3.2 2 1 0 2 2 2 1 SOX transcription factor DUF2431 PF10354.9 VBB26409.1 - 1e-25 91.0 0.0 2.4e-25 89.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) EF1_GNE PF00736.19 VBB26409.1 - 6.9e-25 87.1 1.6 6.9e-25 87.1 1.6 1.9 2 1 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 VBB26409.1 - 4.6e-13 49.4 8.5 4.6e-13 49.4 8.5 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GAS PF13851.6 VBB26409.1 - 0.01 15.2 0.4 0.025 13.9 0.4 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 VBB26409.1 - 0.015 15.3 0.5 0.051 13.6 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tmemb_cc2 PF10267.9 VBB26409.1 - 0.034 13.3 0.3 0.034 13.3 0.3 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein MinC_N PF05209.13 VBB26409.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DUF4404 PF14357.6 VBB26409.1 - 0.16 12.6 0.4 1.1 9.9 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF948 PF06103.11 VBB26409.1 - 0.24 11.7 2.6 0.45 10.8 0.1 2.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 VBB26409.1 - 3.3 8.2 5.4 0.48 10.9 0.1 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DHR-2 PF06920.13 VBB26410.1 - 2.9e-98 329.8 0.0 5.7e-97 325.5 0.0 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 VBB26410.1 - 5.9e-42 143.7 0.1 1.2e-41 142.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 VBB26410.1 - 4.5e-16 59.3 0.1 1.1e-15 58.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 VBB26410.1 - 0.0022 18.5 0.0 0.0067 16.9 0.0 1.9 1 0 0 1 1 1 1 PH domain LRR_8 PF13855.6 VBB26411.1 - 1.7e-19 69.3 8.3 5.3e-12 45.3 2.9 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 VBB26411.1 - 6.1e-10 39.2 10.6 9.7e-06 25.8 0.5 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Baculo_F PF12259.8 VBB26411.1 - 0.00018 20.2 0.4 0.00027 19.6 0.4 1.1 1 0 0 1 1 1 1 Baculovirus F protein LRR_1 PF00560.33 VBB26411.1 - 0.0025 18.1 11.0 14 6.7 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat DnaJ-X PF14308.6 VBB26411.1 - 0.011 15.2 0.4 0.019 14.4 0.1 1.5 2 0 0 2 2 2 0 X-domain of DnaJ-containing LRR_9 PF14580.6 VBB26411.1 - 0.017 14.6 0.8 0.041 13.4 0.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeat UL45 PF05473.12 VBB26411.1 - 0.037 13.7 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Orf78 PF06024.12 VBB26411.1 - 0.085 13.2 0.1 0.33 11.3 0.1 2.1 1 1 0 1 1 1 0 Orf78 (ac78) PBP1_TM PF14812.6 VBB26411.1 - 0.21 12.0 1.4 0.29 11.5 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_6 PF13516.6 VBB26411.1 - 3.4 8.0 11.2 2.3 8.5 1.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeat CrgA PF06781.12 VBB26411.1 - 6.6 6.9 7.0 27 4.9 0.1 3.1 2 1 0 2 2 2 0 Cell division protein CrgA Motile_Sperm PF00635.26 VBB26412.1 - 3.7e-05 23.5 0.0 0.00024 20.9 0.0 2.2 2 1 1 3 3 3 1 MSP (Major sperm protein) domain Laminin_II PF06009.12 VBB26413.1 - 0.0082 16.2 5.1 0.0082 16.2 5.1 7.7 3 2 4 8 8 8 1 Laminin Domain II bZIP_1 PF00170.21 VBB26413.1 - 0.012 15.7 2.0 0.012 15.7 2.0 12.7 10 3 5 15 15 15 0 bZIP transcription factor DUF4745 PF15923.5 VBB26413.1 - 0.8 9.7 3.6 12 5.9 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4745) VKOR PF07884.14 VBB26415.1 - 3.2e-10 40.3 0.4 3.9e-10 40.0 0.4 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DUF1240 PF06836.12 VBB26415.1 - 0.014 15.9 1.1 0.02 15.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Tfb4 PF03850.14 VBB26416.1 - 3.1e-41 141.7 0.4 2.9e-39 135.2 0.4 2.2 1 1 0 1 1 1 1 Transcription factor Tfb4 CTD_bind PF04818.13 VBB26416.1 - 7.3e-05 23.5 0.0 0.00046 20.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 VBB26416.1 - 0.0041 17.6 2.6 0.007 16.8 0.1 2.4 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 zf_UBZ PF18439.1 VBB26416.1 - 0.0081 15.7 0.1 0.024 14.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 VBB26416.1 - 0.11 12.7 0.7 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-C2H2_12 PF18112.1 VBB26416.1 - 0.46 11.0 3.8 1.1 9.8 0.0 2.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain RRM_1 PF00076.22 VBB26417.1 - 3.2e-19 68.5 0.0 5.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4602 PF15375.6 VBB26417.1 - 1.6e-12 47.9 5.4 1.6e-12 47.9 5.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) SPX PF03105.19 VBB26417.1 - 0.00046 20.2 9.4 0.00056 20.0 9.4 1.2 1 0 0 1 1 1 1 SPX domain RRM_3 PF08777.11 VBB26417.1 - 0.046 13.8 0.2 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Apt1 PF10351.9 VBB26417.1 - 0.21 10.4 9.0 0.27 10.0 9.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 VBB26417.1 - 3.7 5.7 12.1 6.1 5.0 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 VBB26417.1 - 6.9 5.3 6.7 9.2 4.9 6.7 1.1 1 0 0 1 1 1 0 Presenilin CwfJ_C_1 PF04677.15 VBB26418.1 - 2.9e-34 117.6 2.3 2.9e-34 117.6 2.3 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 VBB26418.1 - 7.1e-27 94.2 0.2 3.2e-26 92.1 0.2 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 PEHE PF15275.6 VBB26418.1 - 8.8e-08 32.8 2.1 8.8e-08 32.8 2.1 1.7 2 0 0 2 2 2 1 PEHE domain SAS4 PF15460.6 VBB26418.1 - 0.013 15.6 5.5 0.049 13.7 5.5 2.0 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 PAN_1 PF00024.26 VBB26419.1 - 0.00092 19.1 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 VBB26419.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.12 VBB26419.1 - 0.038 13.8 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain Orn_DAP_Arg_deC PF00278.22 VBB26419.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SecA_PP_bind PF01043.20 VBB26420.1 - 0.052 14.2 0.3 0.11 13.2 0.3 1.8 1 1 0 1 1 1 0 SecA preprotein cross-linking domain zf-CCCH_4 PF18044.1 VBB26421.1 - 2.7e-07 30.2 22.6 5.2e-05 22.9 2.5 3.8 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH PF00642.24 VBB26421.1 - 6.4e-07 29.1 20.1 7.5e-06 25.7 0.7 3.9 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 VBB26421.1 - 3.3e-06 27.8 11.2 0.0012 19.6 0.2 3.1 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 VBB26421.1 - 4.1e-05 23.9 17.8 0.00013 22.3 2.7 3.0 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 VBB26421.1 - 0.0003 20.7 20.9 0.0037 17.3 3.7 4.6 3 2 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 VBB26421.1 - 1.5 9.1 13.1 12 6.2 5.5 2.9 1 1 0 2 2 2 0 Zinc-finger containing family Kinesin PF00225.23 VBB26422.1 - 6.2e-113 377.1 2.2 6.2e-113 377.1 2.2 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 VBB26422.1 - 5.9e-29 100.9 0.1 5.9e-29 100.9 0.1 2.7 2 1 0 2 2 2 1 Microtubule binding Cnn_1N PF07989.11 VBB26422.1 - 0.014 15.5 1.6 0.014 15.5 1.6 8.6 5 3 4 9 9 9 0 Centrosomin N-terminal motif 1 zf-H2C2_5 PF13909.6 VBB26423.1 - 0.00075 19.2 1.9 0.0026 17.5 0.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 VBB26423.1 - 0.0015 18.8 3.8 0.022 15.1 1.1 2.7 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 VBB26423.1 - 0.01 16.6 8.9 0.45 11.5 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB26423.1 - 0.11 12.9 8.6 0.16 12.5 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type TFIIS_C PF01096.18 VBB26423.1 - 0.52 10.2 3.7 1.5 8.8 0.7 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_3rep PF18868.1 VBB26423.1 - 0.64 10.7 12.1 8.1 7.1 0.3 4.1 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats Macoilin PF09726.9 VBB26423.1 - 9.7 4.6 14.8 12 4.3 14.8 1.1 1 0 0 1 1 1 0 Macoilin family SBDS_C PF09377.10 VBB26424.1 - 1.7e-34 118.3 1.0 8.4e-34 116.1 0.1 2.0 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 VBB26424.1 - 1.6e-32 111.4 1.8 2.9e-32 110.6 1.8 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein GST_N_3 PF13417.6 VBB26425.1 - 1.4e-21 76.6 0.0 3.1e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 VBB26425.1 - 7.6e-18 64.6 0.1 1.6e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 VBB26425.1 - 1e-15 57.8 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 VBB26425.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 VBB26425.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 VBB26425.1 - 0.0018 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 VBB26425.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin GST_N_4 PF17172.4 VBB26425.1 - 0.053 14.3 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 VBB26425.1 - 0.054 14.1 0.1 0.15 12.6 0.1 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Neur_chan_LBD PF02931.23 VBB26427.1 - 3.6e-42 144.3 2.5 5.9e-42 143.6 2.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB26427.1 - 4e-25 89.3 0.2 1.3e-20 74.5 0.1 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MRP-S31 PF15433.6 VBB26428.1 - 1.2e-64 219.0 3.5 1.4e-64 218.8 3.5 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 TUDOR PF00567.24 VBB26430.1 - 2.3e-21 76.1 0.0 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 VBB26430.1 - 1.1e-10 41.1 1.2 2e-10 40.3 1.2 1.4 1 0 0 1 1 1 1 KH domain Agenet PF05641.12 VBB26430.1 - 0.057 13.9 0.5 0.21 12.1 0.1 2.1 2 0 0 2 2 2 0 Agenet domain DUF1048 PF06304.11 VBB26431.1 - 0.066 13.7 0.1 4.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) PP2C PF00481.21 VBB26433.1 - 5.7e-54 183.5 0.0 9.2e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 VBB26433.1 - 0.072 12.7 0.1 0.38 10.4 0.2 2.1 2 1 0 2 2 2 0 Protein phosphatase 2C Kelch_4 PF13418.6 VBB26434.1 - 1.8e-35 120.7 3.8 4.7e-12 45.7 0.5 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 VBB26434.1 - 5e-22 77.7 0.3 0.0003 21.0 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 VBB26434.1 - 6.9e-21 73.6 8.3 2e-06 27.3 1.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 VBB26434.1 - 6.9e-20 70.6 15.1 1.6e-07 31.1 0.1 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 VBB26434.1 - 8.5e-19 67.1 11.4 3.5e-07 30.3 1.3 5.5 3 1 2 5 5 5 3 Kelch motif Kelch_2 PF07646.15 VBB26434.1 - 6.9e-14 51.2 11.3 0.00034 20.5 0.7 5.6 5 0 0 5 5 5 3 Kelch motif F-box-like PF12937.7 VBB26434.1 - 1.4e-08 34.5 0.2 5e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 VBB26434.1 - 0.00047 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 VBB26434.1 - 0.0022 17.5 0.1 0.0092 15.5 0.0 2.0 2 0 0 2 2 2 1 F-box Cofilin_ADF PF00241.20 VBB26435.1 - 3.3e-26 91.4 0.0 3.7e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_1 PF00036.32 VBB26436.1 - 1.8e-20 70.9 9.4 0.097 12.3 0.0 8.4 8 0 0 8 8 8 7 EF hand EF-hand_6 PF13405.6 VBB26436.1 - 4.4e-16 57.4 9.8 0.39 10.8 0.0 8.9 7 1 1 8 8 8 6 EF-hand domain EF-hand_7 PF13499.6 VBB26436.1 - 2.8e-14 53.3 12.0 0.00024 21.5 0.3 6.2 1 1 4 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB26436.1 - 3.6e-05 24.0 17.0 0.13 12.6 0.0 5.7 5 1 0 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 VBB26436.1 - 5.3e-05 22.5 9.1 0.26 10.8 0.0 6.8 7 0 0 7 7 7 1 EF hand EF-hand_4 PF12763.7 VBB26436.1 - 0.0033 17.3 4.0 6 6.9 0.0 4.5 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 VBB26436.1 - 0.0068 16.2 3.8 10 6.0 0.3 5.1 3 1 3 6 6 6 1 EF-hand domain pair Dockerin_1 PF00404.18 VBB26436.1 - 0.061 13.5 6.4 8.8 6.6 0.0 5.1 3 3 1 5 5 5 0 Dockerin type I domain DUF4058 PF13267.6 VBB26437.1 - 0.051 13.0 2.9 0.082 12.3 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4058) DUF1664 PF07889.12 VBB26437.1 - 0.11 12.5 1.4 0.17 11.9 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CHCH PF06747.13 VBB26438.1 - 1.5e-07 31.4 6.8 2.6e-07 30.6 6.8 1.4 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 VBB26438.1 - 1.7e-06 28.3 4.6 2.1e-06 28.0 4.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Glyoxalase PF00903.25 VBB26439.1 - 0.00028 21.1 0.1 0.23 11.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 VBB26439.1 - 0.042 13.9 1.8 0.29 11.2 0.1 2.7 3 0 0 3 3 3 0 CppA N-terminal SUN PF03856.13 VBB26439.1 - 0.054 12.9 0.4 0.095 12.1 0.0 1.5 2 0 0 2 2 2 0 Beta-glucosidase (SUN family) Sld5 PF05916.11 VBB26443.1 - 0.0015 19.0 0.1 0.0038 17.7 0.0 1.8 2 1 0 2 2 2 1 GINS complex protein Dak1 PF02733.17 VBB26444.1 - 2.1e-104 348.8 0.0 2.8e-104 348.4 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 VBB26444.1 - 4.6e-37 127.6 0.6 1.1e-36 126.3 0.6 1.7 1 0 0 1 1 1 1 DAK2 domain ARL2_Bind_BART PF11527.8 VBB26446.1 - 1.4e-16 60.6 1.9 1.4e-16 60.6 1.9 2.7 1 1 1 2 2 2 1 The ARF-like 2 binding protein BART Gln-synt_C-ter PF18318.1 VBB26446.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.1 4 0 0 4 4 4 0 Glutamine synthetase C-terminal domain RNase_J_C PF17770.1 VBB26446.1 - 1 10.4 5.5 0.92 10.6 1.1 2.8 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DSL PF01414.19 VBB26447.1 - 2.7e-15 56.4 6.2 2.7e-15 56.4 6.2 5.8 2 1 4 6 6 6 2 Delta serrate ligand Ly49 PF08391.10 VBB26447.1 - 0.12 12.7 2.3 0.51 10.7 2.3 2.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4492 PF14899.6 VBB26447.1 - 0.13 12.2 1.1 0.35 10.8 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) TMEM154 PF15102.6 VBB26447.1 - 1.7 8.5 5.9 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family Dna2 PF08696.11 VBB26448.1 - 0.26 11.1 4.6 0.18 11.6 1.8 1.9 2 0 0 2 2 2 0 DNA replication factor Dna2 HMG_box PF00505.19 VBB26448.1 - 3.5 8.1 15.5 8.7 6.8 0.4 4.1 3 2 0 3 3 3 0 HMG (high mobility group) box Sigma70_ner PF04546.13 VBB26448.1 - 3.6 7.4 10.5 2.2 8.1 0.2 2.6 2 1 0 2 2 2 0 Sigma-70, non-essential region NAGidase PF07555.13 VBB26449.1 - 1.7e-78 263.9 0.0 2.6e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase EIID-AGA PF03613.14 VBB26449.1 - 0.05 12.8 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component Myotub-related PF06602.14 VBB26450.1 - 5.6e-120 400.5 0.0 6.9e-120 400.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 3-PAP PF12578.8 VBB26450.1 - 0.038 13.7 0.9 0.091 12.5 0.9 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein Ion_trans_2 PF07885.16 VBB26452.1 - 2.6e-15 56.1 25.5 1e-14 54.2 9.5 3.0 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB26452.1 - 2.1e-06 27.1 2.2 4.5e-06 26.1 2.2 1.6 1 1 0 1 1 1 1 Ion transport protein OPT PF03169.15 VBB26452.1 - 0.032 12.9 1.8 0.052 12.2 1.8 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF2207 PF09972.9 VBB26452.1 - 0.077 11.8 2.2 0.06 12.1 0.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4175 PF13779.6 VBB26452.1 - 0.093 10.6 0.7 1.4 6.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) CrgA PF06781.12 VBB26452.1 - 0.71 10.0 4.3 22 5.2 0.1 2.8 1 1 1 2 2 2 0 Cell division protein CrgA zinc_ribbon_16 PF17034.5 VBB26453.1 - 2.6e-05 24.4 17.5 0.00014 22.1 17.5 2.4 1 1 0 1 1 1 1 Zinc-ribbon like family Borrelia_lipo_1 PF05714.11 VBB26453.1 - 0.065 13.0 0.3 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DPM2 PF07297.12 VBB26454.1 - 0.17 12.2 0.8 2.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Ndr PF03096.14 VBB26456.1 - 7.9e-91 303.7 0.4 9.1e-91 303.5 0.4 1.0 1 0 0 1 1 1 1 Ndr family ACP_syn_III PF08545.10 VBB26456.1 - 0.019 14.8 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDA1_CD39 PF01150.17 VBB26457.1 - 4.3e-125 417.7 0.0 1.2e-124 416.3 0.0 1.5 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Catalase PF00199.19 VBB26457.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Catalase CPL PF08144.11 VBB26458.1 - 3.1e-23 82.7 0.2 9.8e-22 77.8 0.0 3.2 2 1 0 2 2 2 1 CPL (NUC119) domain EamA PF00892.20 VBB26459.1 - 5.4e-12 46.1 31.9 3.9e-06 27.1 13.6 3.4 2 2 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 VBB26459.1 - 1.6e-07 30.9 5.2 2.4e-07 30.2 0.4 2.3 2 1 0 2 2 2 1 Nucleotide-sugar transporter SLC35F PF06027.12 VBB26459.1 - 8e-06 25.6 21.8 3e-05 23.7 18.5 2.6 2 1 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 VBB26459.1 - 2.3e-05 23.9 9.6 2.3e-05 23.9 9.6 1.6 1 1 1 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 VBB26459.1 - 0.0003 19.8 5.5 0.0003 19.8 5.5 2.9 3 0 0 3 3 3 2 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 VBB26459.1 - 0.016 15.3 0.8 0.17 12.0 0.1 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 tRNA-synt_1d PF00750.19 VBB26460.1 - 4.7e-49 167.2 2.1 3.4e-28 98.6 0.2 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 VBB26460.1 - 4.5e-17 62.3 1.1 1.3e-16 60.8 0.0 2.3 3 0 0 3 3 3 1 DALR anticodon binding domain PRKCSH-like PF12999.7 VBB26461.1 - 1.1e-39 136.0 10.6 1.1e-39 136.0 10.6 2.2 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 VBB26461.1 - 6.2e-25 87.7 1.3 8.9e-25 87.2 0.3 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein EF-hand_5 PF13202.6 VBB26461.1 - 3.8e-10 38.8 0.8 0.00014 21.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 VBB26461.1 - 3.3e-09 35.6 1.0 0.00074 18.9 0.0 2.7 1 1 1 2 2 2 2 EF hand EF-hand_8 PF13833.6 VBB26461.1 - 8.8e-09 35.1 0.3 0.00076 19.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB26461.1 - 1.6e-08 33.8 0.6 0.0011 18.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 VBB26461.1 - 1.6e-06 28.5 3.8 0.00083 19.8 0.4 2.7 1 1 0 2 2 2 2 EF-hand domain pair PRKCSH PF07915.13 VBB26461.1 - 6.7e-06 27.0 0.9 6.7e-06 27.0 0.9 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 VBB26461.1 - 0.044 14.0 19.5 0.049 13.9 1.3 3.1 2 1 0 2 2 2 0 Low-density lipoprotein receptor domain class A zf-C2H2_7 PF15269.6 VBB26461.1 - 0.33 11.1 1.6 0.43 10.7 0.5 1.8 2 0 0 2 2 1 0 Zinc-finger DUF3437 PF11919.8 VBB26461.1 - 0.68 9.9 2.5 1.3 9.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) FapA PF03961.13 VBB26461.1 - 1.2 7.7 9.6 2.7 6.5 7.5 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A SPARC_Ca_bdg PF10591.9 VBB26461.1 - 1.6 9.1 8.6 4.9 7.5 4.7 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Nup54_57_C PF18570.1 VBB26461.1 - 8 6.1 10.4 0.5 10.0 0.9 2.8 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain Y_phosphatase PF00102.27 VBB26462.1 - 1e-56 192.2 0.0 1.2e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB26462.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Beta-lactamase PF00144.24 VBB26463.1 - 1.4e-69 234.9 0.0 1.8e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase BLM10_mid PF16507.5 VBB26465.1 - 4.7e-54 183.9 16.2 6.2e-27 94.4 0.2 2.8 3 0 0 3 3 3 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 VBB26465.1 - 1.8e-12 47.0 0.0 1.2e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 VBB26465.1 - 0.018 15.3 0.7 6.5 7.3 0.1 3.8 2 0 0 2 2 2 0 HEAT repeat Y_phosphatase PF00102.27 VBB26466.1 - 5.5e-79 265.0 0.0 8e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 VBB26466.1 - 3.3e-12 46.6 0.1 3.6e-06 27.2 0.0 4.5 4 0 0 4 4 4 2 Fibronectin type III domain DSPc PF00782.20 VBB26466.1 - 0.0031 17.3 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB26466.1 - 0.11 12.7 0.0 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Alg6_Alg8 PF03155.15 VBB26468.1 - 1.1e-27 97.2 3.9 1.4e-27 96.8 3.5 1.4 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Tyr-DNA_phospho PF06087.12 VBB26469.1 - 0.056 12.3 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Chordopox_L2 PF05803.12 VBB26469.1 - 0.061 13.2 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus L2 protein UBA PF00627.31 VBB26470.1 - 5.4e-25 86.9 1.0 5.2e-13 48.6 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 VBB26470.1 - 2.9e-23 81.3 12.5 4.9e-23 80.6 12.5 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 VBB26470.1 - 6.6e-18 64.2 0.1 1.1e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.10 VBB26470.1 - 5.2e-05 23.0 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.9 VBB26470.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 VBB26470.1 - 0.0006 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 VBB26470.1 - 0.0017 18.1 0.2 0.0029 17.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 VBB26470.1 - 0.019 15.3 0.2 0.035 14.5 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1421 PF07223.11 VBB26470.1 - 0.032 14.0 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Ubiquitin_2 PF14560.6 VBB26470.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF3135 PF11333.8 VBB26470.1 - 0.092 13.0 0.4 0.35 11.2 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) DnaB_2 PF07261.11 VBB26470.1 - 0.093 12.5 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment Sel1 PF08238.12 VBB26471.1 - 1.2e-10 41.7 0.0 0.039 14.7 0.0 5.3 5 0 0 5 5 5 4 Sel1 repeat Porin_3 PF01459.22 VBB26472.1 - 3.4e-57 193.9 0.1 4.9e-57 193.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic porin Porin_3 PF01459.22 VBB26473.1 - 7.5e-18 65.0 0.0 4.5e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic porin SPRY PF00622.28 VBB26474.1 - 6.5e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 VBB26474.1 - 1.5e-09 38.0 4.0 3.3e-09 36.9 4.0 1.6 1 0 0 1 1 1 1 SOCS box Peptidase_M14 PF00246.24 VBB26475.1 - 7.4e-24 85.0 0.2 8.7e-24 84.8 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.24 VBB26476.1 - 4.4e-36 125.2 0.0 5.7e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 VBB26476.1 - 5.2e-05 23.6 0.1 8.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Strabismus PF06638.11 VBB26478.1 - 1.2e-130 436.6 0.1 2e-130 435.8 0.1 1.3 1 0 0 1 1 1 1 Strabismus protein UCH PF00443.29 VBB26478.1 - 3.9e-48 164.2 0.2 8.4e-48 163.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB26478.1 - 4.7e-18 65.9 0.0 1.4e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 VBB26478.1 - 1.6e-11 44.4 0.0 4.3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 MATH domain Chol_subst-bind PF09129.11 VBB26478.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding HKR_ArcB_TM PF18415.1 VBB26478.1 - 0.9 10.4 4.1 3 8.7 4.1 1.9 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain Arf PF00025.21 VBB26480.1 - 2.2e-73 245.4 0.1 2.5e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB26480.1 - 3.8e-15 56.1 0.1 5.6e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB26480.1 - 3e-13 49.7 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 VBB26480.1 - 2.7e-11 43.2 0.8 1.2e-07 31.2 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 VBB26480.1 - 1.3e-09 37.7 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 VBB26480.1 - 1.5e-09 37.6 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB26480.1 - 4.3e-05 23.6 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 VBB26480.1 - 0.0086 16.6 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 VBB26480.1 - 0.012 14.6 0.0 0.28 10.1 0.0 2.2 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 VBB26480.1 - 0.015 15.2 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 VBB26480.1 - 0.07 12.7 0.5 10 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 VBB26480.1 - 0.073 12.8 0.1 5.6 6.7 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SelB-wing_2 PF09106.11 VBB26480.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Ras PF00071.22 VBB26481.1 - 1.5e-45 154.7 0.2 2.1e-43 147.7 0.2 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB26481.1 - 9.7e-27 93.6 0.1 1.8e-24 86.3 0.1 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB26481.1 - 6.2e-13 48.6 0.8 6.9e-12 45.2 0.8 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB26481.1 - 1e-05 25.6 0.0 1.7e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 VBB26481.1 - 0.00047 19.6 0.1 0.00055 19.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 VBB26481.1 - 0.032 13.6 0.0 0.085 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 VBB26481.1 - 0.066 13.2 0.0 0.21 11.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 VBB26481.1 - 0.081 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Troponin-I_N PF11636.8 VBB26482.1 - 0.26 11.2 2.1 0.58 10.2 2.1 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 ComS PF17584.2 VBB26482.1 - 7.3 6.2 7.0 3.5 7.2 0.1 3.0 3 0 0 3 3 3 0 Bacillus competence protein S FA_desaturase PF00487.24 VBB26483.1 - 3.8e-28 99.0 19.0 5.5e-28 98.5 19.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase CBM_14 PF01607.24 VBB26483.1 - 8.2e-05 22.7 0.5 8.2e-05 22.7 0.5 3.5 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain DUF3474 PF11960.8 VBB26483.1 - 0.022 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF5401 PF17380.2 VBB26483.1 - 0.17 9.9 0.3 0.31 9.1 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) LANC_like PF05147.13 VBB26484.1 - 3.5e-112 374.5 7.3 1.2e-57 195.1 0.1 3.2 2 1 1 3 3 3 3 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 VBB26484.1 - 2.1e-05 24.1 1.5 0.6 9.6 0.0 4.1 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 VBB26484.1 - 0.0068 15.0 0.0 0.17 10.3 0.0 2.2 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 DUF4800 PF16057.5 VBB26484.1 - 0.055 12.7 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Glyco_hydro_88 PF07470.13 VBB26484.1 - 0.22 10.6 3.1 18 4.2 0.2 3.8 3 2 1 5 5 5 0 Glycosyl Hydrolase Family 88 Forkhead PF00250.18 VBB26485.1 - 7.6e-39 131.9 0.0 1.3e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 VBB26485.1 - 0.11 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family XK-related PF09815.9 VBB26486.1 - 5e-64 216.5 21.2 1.2e-46 159.4 9.9 2.0 2 0 0 2 2 2 2 XK-related protein PMT_4TMC PF16192.5 VBB26486.1 - 0.98 9.0 12.3 0.073 12.6 3.3 2.4 2 2 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase zf-C4H2 PF10146.9 VBB26488.1 - 1.7e-56 191.9 14.5 2.1e-56 191.6 14.5 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Spc7 PF08317.11 VBB26488.1 - 0.0047 15.8 15.1 0.0069 15.3 15.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-C3HC4_3 PF13920.6 VBB26488.1 - 0.01 15.7 4.3 0.016 15.1 4.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2229 PF09989.9 VBB26488.1 - 0.012 15.3 3.7 0.02 14.6 3.7 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF5343 PF17278.2 VBB26488.1 - 0.019 15.0 1.6 0.06 13.4 1.5 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5343) DZR PF12773.7 VBB26488.1 - 0.024 14.6 1.1 0.042 13.9 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Mgr1 PF08602.10 VBB26488.1 - 0.057 12.2 2.3 0.072 11.9 2.3 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Prok-RING_4 PF14447.6 VBB26488.1 - 0.06 13.2 4.0 0.11 12.3 4.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Glutaredoxin2_C PF04399.13 VBB26488.1 - 0.074 12.9 4.2 0.13 12.1 4.0 1.5 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain zf-RING_4 PF14570.6 VBB26488.1 - 0.089 12.6 3.1 0.16 11.8 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FIVAR PF07554.13 VBB26488.1 - 0.11 13.3 6.7 0.28 12.0 6.7 1.8 1 1 0 1 1 1 0 FIVAR domain DUF948 PF06103.11 VBB26488.1 - 0.16 12.3 3.8 13 6.2 3.8 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF148 PF02520.17 VBB26488.1 - 0.27 11.4 14.1 0.76 9.9 14.1 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF2258 PF10015.9 VBB26488.1 - 0.33 11.1 1.9 0.66 10.1 1.3 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) zf-C3HC4_2 PF13923.6 VBB26488.1 - 0.39 10.6 5.2 0.7 9.8 5.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FapA PF03961.13 VBB26488.1 - 0.45 9.1 12.6 0.66 8.5 12.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 VBB26488.1 - 1.1 9.4 19.3 1.6 8.8 19.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 VBB26488.1 - 1.1 8.7 15.9 1.5 8.2 15.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 ZapD PF07072.11 VBB26488.1 - 1.7 8.3 9.4 2.5 7.8 8.5 1.7 1 1 1 2 2 2 0 Cell division protein Jnk-SapK_ap_N PF09744.9 VBB26488.1 - 1.9 8.7 15.9 2.8 8.2 15.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 LMBR1 PF04791.16 VBB26488.1 - 3 6.6 5.9 3.9 6.3 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein 5_nucleotid PF05761.14 VBB26488.1 - 3.7 6.3 7.7 5.2 5.9 7.7 1.1 1 0 0 1 1 1 0 5' nucleotidase family Baculo_IE-1 PF05290.11 VBB26488.1 - 5.2 7.0 7.3 4 7.4 1.6 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) TMPIT PF07851.13 VBB26488.1 - 6.9 5.8 10.3 11 5.2 10.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sec20 PF03908.13 VBB26488.1 - 7 6.6 8.7 14 5.6 0.9 2.4 1 1 0 2 2 2 0 Sec20 FTCD_C PF04961.12 VBB26488.1 - 9.6 5.9 8.0 3.6 7.3 5.4 1.7 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Collagen PF01391.18 VBB26489.1 - 9.9e-24 82.9 101.6 8.2e-10 38.3 32.3 5.1 3 1 2 5 5 5 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26489.1 - 1.7e-16 60.0 0.3 2.3e-16 59.6 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Sigma_M_inh PF17453.2 VBB26489.1 - 0.16 12.4 0.1 0.25 11.8 0.1 1.2 1 0 0 1 1 1 0 Sigma-M inhibitor Rootletin PF15035.6 VBB26490.1 - 2.8e-39 135.1 7.4 2.8e-39 135.1 7.4 12.9 2 1 8 11 11 11 1 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 VBB26490.1 - 0.029 14.4 0.5 0.029 14.4 0.5 22.3 13 6 6 21 21 21 0 TATA element modulatory factor 1 DNA binding DUF2552 PF10827.8 VBB26490.1 - 0.035 14.3 0.2 0.19 12.0 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) PQQ_2 PF13360.6 VBB26491.1 - 5.5e-08 32.7 0.0 0.0052 16.4 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 VBB26491.1 - 1.5e-07 31.0 0.5 0.003 17.4 0.0 3.1 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 VBB26491.1 - 0.00032 21.1 0.9 1.3 9.6 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain ASC PF00858.24 VBB26492.1 - 2.4e-111 372.8 17.1 3.2e-111 372.4 17.1 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel XRN1_D2_D3 PF18334.1 VBB26492.1 - 0.037 14.2 0.1 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain Saf_2TM PF18303.1 VBB26492.1 - 0.071 12.7 1.0 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Pkinase PF00069.25 VBB26493.1 - 1.1e-40 139.6 0.0 1.9e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 VBB26493.1 - 5.1e-39 133.4 0.4 5.1e-39 133.4 0.4 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 VBB26493.1 - 5.7e-26 91.3 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB26493.1 - 6.4e-07 28.5 0.0 0.00029 19.8 0.0 2.6 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 VBB26493.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR19-TM PF15176.6 VBB26493.1 - 0.064 13.3 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain APH PF01636.23 VBB26493.1 - 0.12 12.2 0.0 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tubulin PF00091.25 VBB26494.1 - 8.5e-61 205.6 0.0 1.7e-60 204.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB26494.1 - 4.7e-43 146.4 0.1 7.8e-43 145.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 VBB26494.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 VBB26494.1 - 0.041 13.1 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin like RGS PF00615.19 VBB26495.1 - 9.4e-41 138.8 14.2 6.2e-23 81.3 1.9 2.4 3 0 0 3 3 3 2 Regulator of G protein signaling domain VWC PF00093.18 VBB26496.1 - 0.059 13.7 0.2 0.11 12.9 0.1 1.6 2 1 0 2 2 2 0 von Willebrand factor type C domain Suf PF05843.14 VBB26497.1 - 5e-77 259.8 0.0 3.2e-73 247.3 0.0 3.6 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 VBB26497.1 - 0.019 15.7 7.4 4.5 8.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 VBB26497.1 - 0.46 9.6 6.4 7.1 5.7 0.0 3.9 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference NDUFA12 PF05071.16 VBB26498.1 - 2e-10 41.4 0.2 4.3e-10 40.3 0.1 1.5 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ATP12 PF07542.11 VBB26499.1 - 9.4e-29 100.1 0.7 1.4e-28 99.5 0.7 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein PAP2 PF01569.21 VBB26500.1 - 1.6e-25 89.4 5.4 1.6e-25 89.4 5.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 VBB26500.1 - 3.7e-08 33.3 10.1 4e-07 29.9 10.1 2.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 VBB26500.1 - 0.0063 17.0 5.2 0.0063 17.0 5.2 3.4 3 2 0 3 3 3 1 PAP2 superfamily C-terminal CRIM PF16978.5 VBB26501.1 - 2.9e-13 50.2 0.0 7.3e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 VBB26501.1 - 0.00016 21.9 0.1 0.00031 21.0 0.1 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Y_phosphatase PF00102.27 VBB26502.1 - 2e-66 223.9 3.3 2.8e-66 223.4 3.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB26502.1 - 2.1e-06 27.9 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 VBB26502.1 - 0.00033 20.5 0.1 0.00075 19.3 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB26502.1 - 0.014 15.5 0.2 0.17 12.0 0.0 2.3 1 1 1 2 2 2 0 Inositol hexakisphosphate Sec62 PF03839.16 VBB26503.1 - 3.7e-70 235.8 0.3 3.7e-70 235.8 0.3 1.8 3 0 0 3 3 3 1 Translocation protein Sec62 Presenilin PF01080.17 VBB26503.1 - 0.00067 18.5 0.0 0.00067 18.5 0.0 2.2 2 0 0 2 2 2 1 Presenilin DEP PF00610.21 VBB26503.1 - 0.0034 17.4 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Strabismus PF06638.11 VBB26503.1 - 0.0094 14.7 0.0 0.0094 14.7 0.0 1.7 2 0 0 2 2 1 1 Strabismus protein DDHD PF02862.17 VBB26503.1 - 0.013 15.7 2.0 0.059 13.5 0.0 2.2 2 0 0 2 2 2 0 DDHD domain VIT1 PF01988.19 VBB26503.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 VIT family DUF5308 PF17233.2 VBB26503.1 - 0.11 12.8 0.7 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) FancD2 PF14631.6 VBB26503.1 - 0.13 9.7 9.1 0.23 8.8 9.1 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RNA_pol_Rpc4 PF05132.14 VBB26503.1 - 0.21 12.0 14.9 0.11 13.0 7.2 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Gti1_Pac2 PF09729.9 VBB26503.1 - 3.1 7.8 17.5 0.057 13.5 7.1 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family FAM60A PF15396.6 VBB26503.1 - 3.4 7.6 16.1 0.35 10.8 6.8 2.4 2 0 0 2 2 2 0 Protein Family FAM60A AAA_11 PF13086.6 VBB26503.1 - 4.6 7.0 11.6 0.16 11.8 3.5 2.2 2 0 0 2 2 2 0 AAA domain Pox_Ag35 PF03286.14 VBB26503.1 - 5 6.9 35.0 0.19 11.5 20.1 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Motile_Sperm PF00635.26 VBB26504.1 - 9.8e-14 51.1 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CC2-LZ PF16516.5 VBB26505.1 - 0.0087 16.4 2.4 0.0087 16.4 2.4 1.9 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ARD PF03079.14 VBB26505.1 - 0.093 12.9 2.4 0.13 12.4 2.4 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF641 PF04859.12 VBB26505.1 - 0.21 11.9 4.7 0.27 11.6 4.5 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) FapA PF03961.13 VBB26505.1 - 0.86 8.1 6.2 0.94 8.0 6.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Trm112p PF03966.16 VBB26506.1 - 3.2e-13 50.1 0.0 5.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Trm112p-like protein DUF4230 PF14014.6 VBB26506.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) zf-RanBP PF00641.18 VBB26507.1 - 2.2e-08 33.3 20.7 1.4e-05 24.3 7.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 VBB26507.1 - 8.2 6.5 10.8 29 4.8 10.9 1.9 1 1 1 2 2 2 0 Double zinc ribbon fn3 PF00041.21 VBB26508.1 - 5.5e-88 289.4 9.4 8e-21 74.2 0.2 6.5 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 VBB26508.1 - 1.4e-62 207.7 0.3 4.9e-17 61.8 0.0 6.0 6 0 0 6 6 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB26508.1 - 1.6e-58 195.2 0.6 2.4e-14 53.7 0.0 7.0 7 0 0 7 7 6 4 Immunoglobulin domain Ig_2 PF13895.6 VBB26508.1 - 3.1e-42 142.8 0.0 5.3e-11 42.7 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 VBB26508.1 - 5.1e-33 113.1 0.1 1.3e-09 38.1 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 VBB26508.1 - 9.9e-22 77.2 4.0 0.00081 19.5 0.0 8.5 4 4 3 7 7 7 4 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 VBB26508.1 - 3.6e-21 75.5 2.7 0.00099 19.6 0.3 6.9 6 0 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 VBB26508.1 - 1.5e-15 57.4 0.0 0.068 13.5 0.0 5.7 6 0 0 6 6 5 4 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.12 VBB26508.1 - 5e-10 39.3 0.2 0.033 14.2 0.0 4.4 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.9 VBB26508.1 - 6.6e-10 39.2 0.0 0.16 12.4 0.0 5.4 5 0 0 5 5 5 2 Uncharacterised conserved protein (DUF2369) Ig_4 PF16680.5 VBB26508.1 - 8.1e-09 35.6 0.0 0.37 11.1 0.0 4.8 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 VBB26508.1 - 2.3e-06 27.1 0.0 0.6 9.7 0.0 4.4 4 0 0 4 4 4 1 Immunoglobulin domain fn3_2 PF16893.5 VBB26508.1 - 3.5e-05 23.9 0.0 0.09 12.9 0.0 4.1 4 0 0 4 4 3 1 Fibronectin type III domain C2-set PF05790.15 VBB26508.1 - 5e-05 23.4 0.1 0.018 15.2 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin C2-set domain Tissue_fac PF01108.17 VBB26508.1 - 0.00012 21.9 0.0 4 7.3 0.0 4.9 4 1 1 5 5 5 1 Tissue factor Izumo-Ig PF16706.5 VBB26508.1 - 0.00015 21.8 0.2 7.4 6.7 0.0 5.2 5 1 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB26508.1 - 0.003 17.6 0.0 0.38 10.8 0.0 3.3 3 0 0 3 3 2 1 C17orf99 Ig domain V-set_CD47 PF08204.11 VBB26508.1 - 0.025 14.5 0.0 10 6.1 0.0 2.9 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain SusE PF14292.6 VBB26508.1 - 0.034 14.4 3.4 21 5.4 0.0 5.1 6 0 0 6 6 4 0 SusE outer membrane protein Y_Y_Y PF07495.13 VBB26508.1 - 0.048 13.6 4.6 0.18 11.7 0.3 3.6 5 0 0 5 5 3 0 Y_Y_Y domain Herpes_gE PF02480.16 VBB26508.1 - 0.058 12.1 0.8 3.7 6.2 0.0 3.4 4 0 0 4 4 4 0 Alphaherpesvirus glycoprotein E TM140 PF14985.6 VBB26508.1 - 0.097 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 TM140 protein family Neogenin_C PF06583.12 VBB26508.1 - 6.6 6.5 10.2 2.7 7.7 4.6 2.8 2 1 1 3 3 3 0 Neogenin C-terminus Topoisom_I_N PF02919.15 VBB26509.1 - 9.1e-94 312.9 1.8 9.1e-94 312.9 1.8 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 VBB26509.1 - 2.8e-86 288.5 8.2 2.8e-86 288.5 8.2 3.0 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 VBB26509.1 - 6.1e-33 112.6 2.0 6.1e-33 112.6 2.0 2.6 2 0 0 2 2 2 1 C-terminal topoisomerase domain PspB PF06667.12 VBB26509.1 - 0.27 11.3 1.5 1.2 9.2 1.5 2.1 1 0 0 1 1 1 0 Phage shock protein B HlyIII PF03006.20 VBB26512.1 - 1.4e-18 67.5 26.4 1.7e-18 67.2 26.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2070 PF09843.9 VBB26512.1 - 0.21 9.9 7.6 0.3 9.3 7.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2955 PF11168.8 VBB26512.1 - 0.41 10.5 8.0 0.28 11.0 5.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) DUF758 PF05527.11 VBB26513.1 - 1.1e-57 194.9 7.8 1.3e-57 194.7 7.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Intron_maturas2 PF01348.21 VBB26513.1 - 0.0082 16.1 1.1 0.013 15.4 1.1 1.4 1 0 0 1 1 1 1 Type II intron maturase Swm2 PF17083.5 VBB26513.1 - 0.023 14.7 0.8 0.045 13.7 0.8 1.5 1 0 0 1 1 1 0 Nucleolar protein Swm2 Pico_P2B PF01552.17 VBB26513.1 - 0.062 13.5 3.4 0.08 13.1 1.8 2.1 2 1 1 3 3 3 0 Picornavirus 2B protein MH2 PF03166.14 VBB26514.1 - 1.2e-70 237.5 0.1 1.8e-70 237.0 0.1 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 VBB26514.1 - 7.5e-36 122.5 3.3 1.5e-35 121.5 3.3 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 VBB26514.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Interferon-regulatory factor 3 MFS_2 PF13347.6 VBB26515.1 - 2.6e-13 49.3 32.8 3.4e-08 32.5 22.7 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Spore_YpjB PF09577.10 VBB26515.1 - 0.45 10.3 1.5 4.8 6.9 0.1 2.1 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Ras PF00071.22 VBB26516.1 - 1.6e-54 183.9 0.0 1.9e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB26516.1 - 6.6e-32 110.3 0.0 9.9e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB26516.1 - 5.7e-12 45.4 0.0 8e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB26516.1 - 0.00067 19.6 0.2 0.88 9.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 VBB26516.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 VBB26516.1 - 0.0019 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 VBB26516.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 VBB26516.1 - 0.018 14.4 0.0 0.051 12.9 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 VBB26516.1 - 0.056 13.0 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 VBB26516.1 - 0.059 13.1 0.1 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain Amidase02_C PF12123.8 VBB26516.1 - 0.13 12.0 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_22 PF13401.6 VBB26516.1 - 0.13 12.5 0.1 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAO PF01266.24 VBB26517.1 - 3.6e-30 105.8 0.0 6.8e-30 104.8 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Prefoldin PF02996.17 VBB26517.1 - 4.1e-19 68.7 6.2 1.9e-18 66.5 0.0 3.5 2 1 1 3 3 3 1 Prefoldin subunit MtrG PF04210.13 VBB26517.1 - 0.76 9.7 2.3 63 3.5 0.1 3.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G GPS2_interact PF15784.5 VBB26517.1 - 1.9 9.0 8.5 0.38 11.2 0.4 3.0 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Consortin_C PF15281.6 VBB26518.1 - 0.028 14.4 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Consortin C-terminus Sulfotransfer_1 PF00685.27 VBB26519.1 - 4.1e-30 105.2 0.3 7.4e-17 61.7 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 VBB26519.1 - 0.0006 20.3 0.0 0.065 13.6 0.0 2.5 1 1 1 2 2 2 1 Sulfotransferase family MCLC PF05934.11 VBB26519.1 - 0.053 12.3 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Pre-PUA PF17832.1 VBB26520.1 - 0.042 14.5 0.5 0.13 13.0 0.5 1.9 1 0 0 1 1 1 0 Pre-PUA-like domain SNAP PF14938.6 VBB26521.1 - 1.9e-05 24.2 4.1 2e-05 24.1 4.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TOM20_plant PF06552.12 VBB26521.1 - 0.0077 16.0 0.9 0.01 15.6 0.9 1.3 1 1 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 SH3BP5 PF05276.14 VBB26521.1 - 0.016 15.0 1.8 0.018 14.8 1.8 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) TPR_2 PF07719.17 VBB26521.1 - 0.21 11.8 3.6 18 5.7 0.8 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 VBB26522.1 - 5.8e-66 222.5 0.0 8.1e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 VBB26522.1 - 1.6e-30 105.7 0.3 4.9e-30 104.1 0.2 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 VBB26522.1 - 4.5e-24 84.2 0.0 1e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 VBB26522.1 - 5.1e-13 48.7 0.0 9.9e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 VBB26522.1 - 2.6e-11 43.4 6.0 6.8e-11 42.0 6.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 VBB26522.1 - 0.0071 15.7 0.4 0.017 14.5 0.4 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_S25 PF03297.15 VBB26523.1 - 4.2e-42 142.4 2.3 4.2e-42 142.4 2.3 1.3 1 1 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 VBB26523.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 VBB26523.1 - 0.042 13.7 0.7 0.099 12.5 0.3 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PCI PF01399.27 VBB26523.1 - 0.054 14.0 0.0 0.071 13.6 0.0 1.1 1 0 0 1 1 1 0 PCI domain ADH_N PF08240.12 VBB26524.1 - 3.9e-23 81.4 2.0 9.4e-23 80.2 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 VBB26524.1 - 3e-20 72.5 0.0 5.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 VBB26524.1 - 0.00034 21.7 0.0 0.00062 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 VBB26524.1 - 0.046 13.0 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 VBB26524.1 - 0.057 12.8 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 VBB26524.1 - 0.064 12.7 0.1 0.91 9.0 0.1 2.4 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus tRNA_U5-meth_tr PF05958.11 VBB26525.1 - 2.1e-08 33.5 0.0 3.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 VBB26525.1 - 3e-07 30.3 0.0 6.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB26525.1 - 3e-06 27.9 0.0 8.5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB26525.1 - 0.00052 19.6 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 VBB26525.1 - 0.0012 18.4 0.0 0.004 16.6 0.0 1.9 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 VBB26525.1 - 0.0052 16.2 0.3 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) DUF2603 PF10788.9 VBB26525.1 - 0.017 15.2 1.6 0.079 13.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) Ubie_methyltran PF01209.18 VBB26525.1 - 0.027 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 VBB26525.1 - 0.045 13.4 0.6 0.37 10.5 0.3 2.5 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 VBB26525.1 - 0.097 13.3 0.0 0.31 11.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ADAM_CR_2 PF17771.1 VBB26527.1 - 5.9e-19 68.3 4.5 5.9e-19 68.3 4.5 2.3 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 VBB26527.1 - 8e-06 26.4 0.1 1.8e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 VBB26527.1 - 9e-05 22.7 0.1 0.00013 22.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.19 VBB26527.1 - 0.001 19.0 0.1 0.0021 18.0 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease WD40 PF00400.32 VBB26528.1 - 1.4e-12 47.9 10.4 1.9e-05 25.3 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF2415 PF10313.9 VBB26528.1 - 0.00095 19.0 0.0 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 VBB26528.1 - 0.067 13.5 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Alg14 PF08660.11 VBB26529.1 - 4e-53 179.9 0.0 7.4e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 VBB26529.1 - 0.0082 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain zf-C2H2_2 PF12756.7 VBB26530.1 - 1.6e-28 99.0 19.9 2.7e-17 63.0 6.2 3.7 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 VBB26530.1 - 5.3e-05 23.4 1.5 0.00021 21.5 1.5 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 VBB26530.1 - 0.0071 16.4 1.9 0.0071 16.4 1.9 4.5 5 0 0 5 5 5 1 BED zinc finger zf-C2H2_4 PF13894.6 VBB26530.1 - 0.008 16.9 0.2 0.008 16.9 0.2 4.7 5 0 0 5 5 5 1 C2H2-type zinc finger DUF2256 PF10013.9 VBB26530.1 - 0.14 12.3 0.5 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-nanos PF05741.13 VBB26530.1 - 2.3 8.5 6.5 40 4.6 0.0 3.6 3 0 0 3 3 3 0 Nanos RNA binding domain zf-C2H2 PF00096.26 VBB26530.1 - 4.5 7.9 11.3 0.068 13.7 1.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type HNH_5 PF14279.6 VBB26530.1 - 5.4 7.0 6.3 1 9.3 0.1 3.0 3 0 0 3 3 3 0 HNH endonuclease C2 PF00168.30 VBB26531.1 - 3.2e-46 155.9 0.5 1.7e-21 76.4 0.0 3.4 3 0 0 3 3 3 2 C2 domain FYVE_2 PF02318.16 VBB26531.1 - 3.9e-28 98.0 6.3 1e-27 96.7 6.3 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 VBB26531.1 - 0.31 11.2 7.5 0.71 10.1 7.5 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger FYVE PF01363.21 VBB26531.1 - 1.1 9.4 7.9 3.7 7.8 7.9 1.8 1 0 0 1 1 1 0 FYVE zinc finger Pheromone PF08015.11 VBB26531.1 - 1.5 9.9 4.2 4 8.5 0.4 3.5 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF525 PF04379.14 VBB26532.1 - 7.9e-13 48.5 0.1 1.3e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 VBB26532.1 - 6.5e-06 26.6 0.0 2.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Ubie_methyltran PF01209.18 VBB26533.1 - 4.6e-89 297.8 0.1 5.9e-89 297.4 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 VBB26533.1 - 9.6e-21 74.3 0.1 2.6e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB26533.1 - 1.5e-20 73.6 0.1 4.2e-19 69.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB26533.1 - 4e-12 46.2 0.0 6.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB26533.1 - 1.5e-11 44.9 0.0 3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB26533.1 - 4.8e-09 36.3 0.0 7.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 VBB26533.1 - 1.1e-05 25.4 0.1 0.00063 19.7 0.0 2.4 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 VBB26533.1 - 0.0024 17.2 0.1 0.0047 16.2 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 VBB26533.1 - 0.006 16.1 0.0 0.02 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain CAP_GLY PF01302.25 VBB26534.1 - 1.8e-15 56.7 4.5 1.2e-06 28.4 0.1 3.3 3 0 0 3 3 3 2 CAP-Gly domain UCH PF00443.29 VBB26534.1 - 2.4e-05 24.0 0.1 8.2e-05 22.2 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 VBB26534.1 - 2.3 8.4 4.7 5.7 7.1 4.7 1.7 1 0 0 1 1 1 0 MYND finger CPL PF08144.11 VBB26535.1 - 0.049 14.0 1.5 0.09 13.1 1.5 1.5 1 1 0 1 1 1 0 CPL (NUC119) domain Ribosomal_L18_c PF14204.6 VBB26535.1 - 0.051 14.5 0.1 0.59 11.1 0.2 2.1 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Rhomboid PF01694.22 VBB26536.1 - 3e-34 118.2 8.0 3e-34 118.2 8.0 1.8 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.6 VBB26536.1 - 2.1e-10 40.9 1.0 3.6e-10 40.1 1.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 VBB26536.1 - 3.5e-09 36.4 0.2 0.00096 19.0 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB26536.1 - 1.3e-08 33.7 0.3 0.0043 16.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 VBB26536.1 - 1e-06 27.9 1.4 0.034 13.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 VBB26536.1 - 1.1e-06 28.1 1.5 0.0071 16.2 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 VBB26536.1 - 0.028 14.7 0.2 0.098 13.0 0.1 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2207 PF09972.9 VBB26536.1 - 4.4 6.0 6.6 2.4 6.8 4.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PDZ PF00595.24 VBB26537.1 - 3.7e-18 65.7 0.0 4.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB26537.1 - 8.9e-09 35.1 0.0 1.6e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB26537.1 - 2.1e-07 31.1 0.0 2.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 PDZ domain ABC_tran PF00005.27 VBB26538.1 - 4.5e-28 98.5 0.0 8.2e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 VBB26538.1 - 4.4e-17 62.2 54.2 1.1e-14 54.3 33.3 3.4 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 VBB26538.1 - 9.8e-14 51.9 1.3 1.9e-07 31.2 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 VBB26538.1 - 1.2e-05 24.9 0.1 0.028 13.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 VBB26538.1 - 0.00035 20.5 0.0 0.00097 19.1 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 VBB26538.1 - 0.0029 18.1 0.1 0.0067 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 VBB26538.1 - 0.0072 16.0 0.2 0.017 14.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 VBB26538.1 - 0.0073 16.1 0.2 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 VBB26538.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DLIC PF05783.11 VBB26538.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RNase_Zc3h12a_2 PF14626.6 VBB26538.1 - 0.15 12.3 1.4 4 7.7 0.1 2.5 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain ABC2_membrane_2 PF12679.7 VBB26538.1 - 0.32 10.2 14.8 0.69 9.1 11.7 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 VBB26539.1 - 5.2e-14 52.9 0.0 8.3e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 VBB26539.1 - 0.066 13.7 0.2 0.13 12.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 VBB26539.1 - 0.12 12.0 0.5 0.44 10.1 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 VBB26539.1 - 0.15 11.9 0.4 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase PFK PF00365.20 VBB26540.1 - 2.2e-195 647.4 4.1 9.3e-108 359.9 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase AAA_21 PF13304.6 VBB26540.1 - 5.7e-05 23.1 0.0 8.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 VBB26540.1 - 0.0014 19.2 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter FAM212 PF15342.6 VBB26540.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 FAM212 family Metallophos PF00149.28 VBB26541.1 - 1.6e-06 28.7 2.2 3.4e-06 27.7 2.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4083 PF13314.6 VBB26541.1 - 0.012 15.5 0.8 0.025 14.5 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Tmemb_170 PF10190.9 VBB26542.1 - 9.8e-27 93.4 14.5 1.5e-26 92.9 14.5 1.2 1 0 0 1 1 1 1 Putative transmembrane protein 170 TFIIS_C PF01096.18 VBB26542.1 - 1.2e-14 53.9 4.7 2.6e-14 52.8 4.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 VBB26542.1 - 0.084 12.6 3.5 0.68 9.6 3.5 2.5 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain ADK_lid PF05191.14 VBB26542.1 - 0.31 11.1 1.8 0.46 10.5 0.2 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF3716 PF12511.8 VBB26542.1 - 2.3 8.3 6.3 0.48 10.5 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) zf-HIT PF04438.16 VBB26542.1 - 3 7.8 6.8 14 5.7 0.7 2.5 2 0 0 2 2 2 0 HIT zinc finger Rpr2 PF04032.16 VBB26542.1 - 5 7.5 7.3 0.81 10.0 3.2 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain LSM PF01423.22 VBB26543.1 - 0.076 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 LSM domain DUF150_C PF17384.2 VBB26543.1 - 0.085 13.0 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Ribosomal_L37 PF08561.10 VBB26544.1 - 6.4e-07 29.9 0.1 7.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 CBF_beta PF02312.17 VBB26545.1 - 1.5e-22 80.0 0.0 3e-21 75.8 0.0 2.0 1 1 0 1 1 1 1 Core binding factor beta subunit SWIRM-assoc_1 PF16495.5 VBB26545.1 - 0.04 13.9 1.0 0.088 12.8 0.0 1.9 2 0 0 2 2 2 0 SWIRM-associated region 1 Gly-zipper_YMGG PF13441.6 VBB26547.1 - 0.047 13.4 5.0 0.089 12.5 5.0 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 VBB26547.1 - 0.48 10.5 6.8 1.1 9.3 6.8 1.7 1 1 0 1 1 1 0 Glycine zipper YqzM PF14141.6 VBB26547.1 - 0.7 10.0 0.0 0.7 10.0 0.0 2.1 2 1 0 2 2 2 0 YqzM-like protein TraT PF05818.12 VBB26548.1 - 1.5 8.4 6.0 20 4.8 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Peptidase_A17 PF05380.13 VBB26549.1 - 0.00092 19.2 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RT_RNaseH_2 PF17919.1 VBB26549.1 - 0.053 13.6 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF1190 PF06693.11 VBB26550.1 - 0.1 13.0 0.6 0.1 13.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) I-set PF07679.16 VBB26552.1 - 7.3e-286 923.4 8.7 1.8e-17 63.1 0.0 22.3 21 2 0 21 21 21 20 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB26552.1 - 2.8e-255 825.7 33.5 1.5e-15 57.6 0.0 21.2 21 0 0 21 21 21 21 Immunoglobulin domain Ig_2 PF13895.6 VBB26552.1 - 2.6e-186 604.4 15.5 5.9e-11 42.6 0.0 21.1 19 2 2 21 21 21 20 Immunoglobulin domain ig PF00047.25 VBB26552.1 - 1.4e-141 461.1 12.9 6.9e-09 35.8 0.0 22.6 21 2 0 21 21 21 19 Immunoglobulin domain V-set PF07686.17 VBB26552.1 - 4.8e-50 168.3 44.2 0.0032 17.6 0.0 31.2 21 15 6 27 27 26 9 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB26552.1 - 5e-48 161.4 0.0 0.0038 17.6 0.0 19.4 20 0 0 20 20 20 7 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 VBB26552.1 - 8.7e-42 141.1 13.0 0.15 12.1 0.0 19.4 19 1 0 19 19 19 10 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB26552.1 - 1.2e-36 124.0 0.1 0.023 14.2 0.0 17.8 19 0 0 19 19 19 7 Immunoglobulin domain Ig_4 PF16680.5 VBB26552.1 - 1.1e-30 105.7 7.3 0.44 10.8 0.0 19.3 21 0 0 21 21 20 6 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 VBB26552.1 - 3e-20 72.1 0.7 0.54 10.3 0.0 15.4 20 1 0 20 20 17 4 C17orf99 Ig domain Receptor_2B4 PF11465.8 VBB26552.1 - 5.4e-16 58.7 0.3 0.049 13.8 0.0 11.7 14 0 0 14 14 13 2 Natural killer cell receptor 2B4 C1-set PF07654.15 VBB26552.1 - 9.2e-13 48.4 15.2 1.3 9.4 0.0 14.8 18 1 1 19 19 16 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 VBB26552.1 - 4.2e-12 45.9 4.5 11 6.1 0.0 14.7 19 0 0 19 19 18 0 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 VBB26552.1 - 3.1e-08 33.5 0.0 13 5.9 0.0 10.0 10 1 1 11 11 11 0 Penicillin-Binding Protein C-terminus Family V-set_CD47 PF08204.11 VBB26552.1 - 7e-07 29.3 27.7 0.16 12.0 0.2 13.8 13 4 4 17 17 17 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 VBB26552.1 - 1.3e-06 28.1 4.7 5.3 6.9 0.0 10.0 13 0 0 13 13 10 1 Adenovirus E3 region protein CR1 G2F PF07474.12 VBB26552.1 - 0.00052 19.8 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 G2F domain Herpes_gE PF02480.16 VBB26552.1 - 0.001 18.0 0.0 6.1 5.5 0.0 5.4 6 0 0 6 6 6 1 Alphaherpesvirus glycoprotein E EGF_CA PF07645.15 VBB26553.1 - 4.6e-36 122.8 77.8 1.9e-09 37.6 7.9 6.5 7 1 0 7 7 7 5 Calcium-binding EGF domain cEGF PF12662.7 VBB26553.1 - 2.5e-19 68.8 53.7 5.5e-07 29.4 0.8 7.4 8 0 0 8 8 8 6 Complement Clr-like EGF-like EGF_3 PF12947.7 VBB26553.1 - 4e-05 23.7 47.8 0.011 15.9 7.1 7.0 3 2 2 5 5 5 4 EGF domain FXa_inhibition PF14670.6 VBB26553.1 - 0.0014 18.9 63.7 0.097 13.0 3.5 7.2 3 2 3 6 6 6 3 Coagulation Factor Xa inhibitory site hEGF PF12661.7 VBB26553.1 - 0.018 15.6 1.0 0.018 15.6 1.0 9.1 11 1 0 11 11 11 0 Human growth factor-like EGF EGF PF00008.27 VBB26553.1 - 0.62 10.4 72.0 0.053 13.8 4.3 8.5 7 2 1 8 8 8 0 EGF-like domain GBP_PSP PF02425.15 VBB26553.1 - 1.1 8.9 4.0 7.7 6.3 0.1 3.3 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide SURF6 PF04935.12 VBB26554.1 - 7.3e-27 94.5 53.0 7.3e-27 94.5 53.0 2.4 1 1 1 2 2 2 1 Surfeit locus protein 6 LMBR1 PF04791.16 VBB26554.1 - 0.45 9.4 15.4 0.017 14.0 9.4 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein Miga PF10265.9 VBB26555.1 - 1.9e-117 393.5 0.1 2.2e-117 393.3 0.1 1.2 1 0 0 1 1 1 1 Mitoguardin CBM_14 PF01607.24 VBB26556.1 - 7.4e-45 150.9 66.2 3.3e-09 36.7 5.3 6.2 6 0 0 6 6 6 6 Chitin binding Peritrophin-A domain Imm25 PF15564.6 VBB26556.1 - 0.0017 18.3 1.0 0.61 10.0 0.2 3.4 3 0 0 3 3 3 1 Immunity protein 25 Eaf7 PF07904.13 VBB26557.1 - 2.6e-19 69.6 1.4 8e-19 68.0 1.4 1.8 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Nup84_Nup100 PF04121.13 VBB26558.1 - 2.2e-70 237.7 16.5 3.3e-70 237.1 16.5 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Pkinase_Tyr PF07714.17 VBB26558.1 - 8.3e-27 94.1 0.0 1.8e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB26558.1 - 5.4e-22 78.4 0.3 1.4e-21 77.1 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 VBB26558.1 - 0.00068 19.0 0.1 0.0015 18.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF948 PF06103.11 VBB26558.1 - 0.071 13.4 0.1 0.77 10.1 0.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Herpes_UL6 PF01763.16 VBB26559.1 - 7.7e-05 21.4 10.1 7.7e-05 21.4 10.1 3.4 1 1 1 3 3 3 1 Herpesvirus UL6 like DUF3584 PF12128.8 VBB26559.1 - 0.017 12.7 49.5 0.026 12.1 49.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.21 VBB26559.1 - 0.024 14.7 14.8 0.024 14.7 14.8 8.1 3 2 6 9 9 9 0 bZIP transcription factor MbeD_MobD PF04899.12 VBB26559.1 - 0.07 13.3 24.3 2.3 8.4 0.1 5.7 2 1 1 4 4 4 0 MbeD/MobD like Fmp27_GFWDK PF10347.9 VBB26559.1 - 0.15 12.2 2.0 0.26 11.4 0.2 2.3 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain Golgin_A5 PF09787.9 VBB26559.1 - 0.47 9.9 69.8 0.18 11.2 5.0 4.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 VBB26559.1 - 1.3 8.8 74.3 0.062 13.1 23.3 4.4 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH YojJ PF10372.9 VBB26559.1 - 3.5 7.8 14.1 4.4 7.5 1.9 4.2 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus CENP-F_leu_zip PF10473.9 VBB26559.1 - 4.9 7.2 80.6 1.4 8.9 21.3 4.7 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 VBB26559.1 - 9.9 6.6 65.5 0.054 14.0 14.3 3.7 1 1 2 3 3 3 0 Fez1 Upf2 PF04050.14 VBB26560.1 - 0.0055 17.4 0.6 0.0055 17.4 0.6 2.1 2 0 0 2 2 2 1 Up-frameshift suppressor 2 SH2 PF00017.24 VBB26561.1 - 9.3e-12 44.9 0.0 2.9e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 SH2 domain STD1 PF17235.2 VBB26561.1 - 0.0011 18.7 0.5 0.0017 18.0 0.5 1.2 1 0 0 1 1 1 1 STD1/MTH1 SH2_2 PF14633.6 VBB26561.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 SH2 domain Otopetrin PF03189.13 VBB26562.1 - 0.32 9.8 2.6 0.41 9.4 2.6 1.1 1 0 0 1 1 1 0 Otopetrin Cyt_bd_oxida_I PF01654.17 VBB26562.1 - 1.7 7.2 6.0 2.2 6.8 6.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I ATP1G1_PLM_MAT8 PF02038.16 VBB26562.1 - 6.1 6.4 13.4 3 7.3 4.6 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Phage_holin_3_6 PF07332.11 VBB26562.1 - 7 6.7 13.6 9.9 6.2 13.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF229 PF02995.17 VBB26563.1 - 2e-81 274.1 12.0 1.7e-80 271.1 12.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Peptidase_C13 PF01650.18 VBB26563.1 - 1.1e-78 264.4 0.1 3.8e-78 262.5 0.1 1.9 1 0 0 1 1 1 1 Peptidase C13 family Sulfatase PF00884.23 VBB26563.1 - 5.9e-06 25.9 1.6 1.3e-05 24.7 0.2 2.1 2 0 0 2 2 2 1 Sulfatase Forkhead PF00250.18 VBB26563.1 - 0.0031 17.7 0.2 0.0031 17.7 0.2 2.6 3 0 0 3 3 3 1 Forkhead domain Urm1 PF09138.11 VBB26563.1 - 0.11 12.9 0.1 0.89 9.9 0.0 2.6 3 0 0 3 3 3 0 Urm1 (Ubiquitin related modifier) Frizzled PF01534.17 VBB26564.1 - 8.3e-112 373.4 22.8 1.4e-111 372.7 22.8 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 VBB26564.1 - 1.5e-24 86.8 3.1 3.4e-24 85.6 3.1 1.6 1 0 0 1 1 1 1 Fz domain DUF2269 PF10027.9 VBB26564.1 - 0.0036 17.4 6.5 0.01 15.9 5.5 2.2 1 1 1 2 2 2 1 Predicted integral membrane protein (DUF2269) Snf7 PF03357.21 VBB26565.1 - 2e-06 27.5 0.9 2.1e-06 27.4 0.9 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 VBB26565.1 - 0.0026 17.7 1.0 0.0031 17.5 1.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 VBB26565.1 - 0.014 15.3 0.2 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Prefoldin subunit Dynamitin PF04912.14 VBB26565.1 - 0.019 14.3 0.1 0.02 14.2 0.1 1.0 1 0 0 1 1 1 0 Dynamitin SMK-1 PF04802.15 VBB26566.1 - 1.4e-69 233.8 3.5 2.1e-69 233.2 2.7 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 MADF_DNA_bdg PF10545.9 VBB26567.1 - 2.9e-11 43.5 0.1 7.7e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB26567.1 - 0.0031 17.9 0.0 0.0084 16.5 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Ribosomal_L35Ae PF01247.18 VBB26568.1 - 5.8e-40 135.4 1.3 7.6e-40 135.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 VBB26568.1 - 0.021 15.1 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain SRP68 PF16969.5 VBB26569.1 - 1.2e-111 374.4 7.7 2e-111 373.7 7.7 1.3 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 VBB26569.1 - 0.0027 17.7 7.8 0.44 10.8 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF1398 PF07166.11 VBB26569.1 - 0.015 15.4 1.2 2.6 8.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1398) TPR_1 PF00515.28 VBB26569.1 - 0.029 14.2 2.0 0.34 10.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PerC PF06069.11 VBB26569.1 - 0.21 11.9 1.7 63 3.9 0.1 3.7 3 0 0 3 3 3 0 PerC transcriptional activator PhoU PF01895.19 VBB26569.1 - 0.65 10.5 6.5 5.3 7.6 0.3 3.8 4 0 0 4 4 4 0 PhoU domain LSM PF01423.22 VBB26570.1 - 6.6e-19 67.4 0.2 8.9e-19 67.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 VBB26570.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Hfq protein BSD PF03909.17 VBB26571.1 - 1.2e-14 54.0 0.2 3.2e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 BSD domain Peripla_BP_2 PF01497.18 VBB26571.1 - 0.0041 16.7 0.9 0.0063 16.1 0.9 1.2 1 0 0 1 1 1 1 Periplasmic binding protein TMEM18 PF14770.6 VBB26572.1 - 0.09 12.8 0.3 0.15 12.1 0.1 1.4 2 0 0 2 2 2 0 Transmembrane protein 18 zf-C2H2 PF00096.26 VBB26573.1 - 0.035 14.6 7.0 0.6 10.7 1.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26573.1 - 0.54 11.2 6.5 3.5 8.7 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger EF-hand_6 PF13405.6 VBB26574.1 - 0.069 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 VBB26574.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 EF hand DUF4107 PF13389.6 VBB26576.1 - 0.09 12.9 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) MAD PF05557.13 VBB26577.1 - 9.4e-18 63.9 4.1 9.4e-18 63.9 4.1 3.1 2 1 1 3 3 3 1 Mitotic checkpoint protein FliJ PF02050.16 VBB26577.1 - 0.085 13.1 31.8 0.33 11.2 6.7 4.2 2 1 1 3 3 3 0 Flagellar FliJ protein HTH_15 PF12324.8 VBB26577.1 - 0.16 11.9 0.0 0.65 10.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DUF4407 PF14362.6 VBB26577.1 - 5.6 6.2 21.1 1.5 8.1 13.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) SYCP2_SLD PF18584.1 VBB26577.1 - 9.7 6.5 8.5 3.2 8.0 1.0 3.1 3 0 0 3 3 3 0 Synaptonemal complex 2 Spt16M-like domain MORN PF02493.20 VBB26578.1 - 2.5e-30 102.5 73.6 3.5e-05 23.4 1.2 9.0 9 0 0 9 9 9 8 MORN repeat BIR PF00653.21 VBB26579.1 - 2.3e-19 69.8 5.4 7.1e-19 68.2 5.4 1.9 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Homeodomain PF00046.29 VBB26580.1 - 3.4e-20 71.6 4.9 7.2e-20 70.6 4.9 1.6 1 0 0 1 1 1 1 Homeodomain DUF599 PF04654.12 VBB26580.1 - 0.015 14.8 4.9 0.1 12.0 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Phage_Coat_B PF05356.11 VBB26580.1 - 1.3 9.0 4.1 0.49 10.3 1.3 1.7 2 0 0 2 2 2 0 Phage Coat protein B Glycoprotein_B PF00606.18 VBB26581.1 - 0.00062 19.3 0.3 0.0011 18.5 0.2 1.5 2 0 0 2 2 2 1 Herpesvirus Glycoprotein B ectodomain APG6_N PF17675.1 VBB26582.1 - 1.5 9.4 10.4 4.4 7.8 10.4 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Sporozoite_P67 PF05642.11 VBB26583.1 - 0.23 9.5 3.1 0.27 9.3 3.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Homeodomain PF00046.29 VBB26584.1 - 1.1e-22 79.7 8.9 1.4e-22 79.3 8.9 1.2 1 0 0 1 1 1 1 Homeodomain CI-B14_5a PF07347.12 VBB26584.1 - 0.018 14.9 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homeobox_KN PF05920.11 VBB26584.1 - 0.02 14.8 0.3 0.056 13.4 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 VBB26584.1 - 0.14 12.5 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DNA_ligase_A_M PF01068.21 VBB26585.1 - 2.6e-36 125.2 0.0 4.8e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RCC1 PF00415.18 VBB26585.1 - 2.1e-25 89.1 0.9 0.00019 22.0 0.0 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB26585.1 - 1e-18 66.6 5.0 0.0016 18.2 0.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BRCT PF00533.26 VBB26585.1 - 3.1e-12 46.7 1.8 2.6e-05 24.5 0.2 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_N PF04675.14 VBB26585.1 - 6.7e-11 42.8 6.4 3.3e-10 40.5 3.2 2.4 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 VBB26585.1 - 6.4e-10 39.3 0.2 0.00029 21.2 0.1 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 VBB26585.1 - 8.8e-07 29.5 0.0 2.7e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region LIG3_BRCT PF16759.5 VBB26585.1 - 0.00053 20.2 0.3 0.045 14.0 0.1 2.7 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain RNA_ligase PF09414.10 VBB26585.1 - 0.0019 18.5 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 RNA ligase PTCB-BRCT PF12738.7 VBB26585.1 - 0.065 13.2 0.3 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 twin BRCT domain LMBR1 PF04791.16 VBB26586.1 - 3.9e-80 270.2 45.9 1.9e-47 162.4 21.4 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Lectin_C PF00059.21 VBB26587.1 - 6.9e-11 42.8 3.5 1.3e-10 41.9 3.5 1.5 1 0 0 1 1 1 1 Lectin C-type domain zf-C2H2_2 PF12756.7 VBB26589.1 - 0.0067 16.7 4.4 0.65 10.4 0.3 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 VBB26589.1 - 0.0077 16.2 4.7 0.048 13.7 0.0 2.7 3 0 0 3 3 3 1 BED zinc finger zf-H2C2_5 PF13909.6 VBB26589.1 - 0.052 13.3 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-CHY PF05495.12 VBB26589.1 - 0.06 13.8 5.2 2 8.9 0.8 2.2 2 0 0 2 2 2 0 CHY zinc finger zf-met PF12874.7 VBB26589.1 - 0.23 11.9 0.6 0.23 11.9 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 VBB26589.1 - 0.38 10.7 4.3 0.73 9.8 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.13 VBB26589.1 - 1.2 9.2 9.0 2.5 8.2 1.3 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 VBB26589.1 - 5 8.2 11.4 4.5 8.4 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB26590.1 - 2.3e-08 34.0 25.1 0.00078 19.8 0.9 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 VBB26590.1 - 6e-08 32.3 24.5 0.00031 20.4 1.5 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-met PF12874.7 VBB26590.1 - 0.00011 22.5 1.2 0.00011 22.5 1.2 3.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 VBB26590.1 - 0.013 16.3 23.9 0.11 13.4 1.8 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger LIM_bind PF01803.16 VBB26590.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 LIM-domain binding protein AKAP95 PF04988.12 VBB26590.1 - 0.017 15.4 0.1 0.017 15.4 0.1 3.1 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) CpXC PF14353.6 VBB26590.1 - 0.087 12.9 9.0 6.5 6.8 0.2 3.4 3 0 0 3 3 3 0 CpXC protein zf-H2C2_2 PF13465.6 VBB26590.1 - 0.12 12.9 22.2 1.7 9.2 0.9 5.6 5 0 0 5 5 5 0 Zinc-finger double domain zinc_ribbon_15 PF17032.5 VBB26590.1 - 0.58 10.9 11.0 2.4 9.0 5.5 2.9 2 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_2 PF12756.7 VBB26590.1 - 0.66 10.3 26.7 1.3 9.4 0.3 4.6 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) His_Phos_1 PF00300.22 VBB26591.1 - 2.7e-17 63.1 0.0 6.6e-16 58.6 0.0 2.6 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) SHE3 PF17078.5 VBB26592.1 - 0.0002 21.2 31.7 0.0002 21.2 31.7 5.5 3 1 2 6 6 6 1 SWI5-dependent HO expression protein 3 BNIP3 PF06553.12 VBB26593.1 - 0.016 14.9 0.5 23 4.6 0.0 3.3 3 0 0 3 3 3 0 BNIP3 DUF418 PF04235.12 VBB26593.1 - 0.05 13.5 0.2 0.076 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) GBP PF02263.19 VBB26595.1 - 2.4e-96 322.0 0.1 3.3e-96 321.6 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 VBB26595.1 - 0.00071 19.1 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 VBB26595.1 - 0.0031 17.9 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain Arf PF00025.21 VBB26596.1 - 2.5e-66 222.4 1.8 4.2e-43 146.8 0.1 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB26596.1 - 1.2e-13 51.0 0.1 3.4e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 VBB26596.1 - 5.7e-12 45.9 0.1 1.6e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 VBB26596.1 - 1.6e-11 43.9 1.7 5.9e-07 29.0 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 VBB26596.1 - 1.9e-09 37.3 0.1 2e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 VBB26596.1 - 3.1e-09 36.5 0.1 4.9e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 VBB26596.1 - 3.3e-06 27.2 0.1 7.3e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 VBB26596.1 - 0.00084 19.9 0.0 0.0024 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 VBB26596.1 - 0.00087 18.3 0.1 0.042 12.8 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 VBB26596.1 - 0.01 16.3 0.0 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 VBB26596.1 - 0.024 14.4 0.0 0.071 12.9 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1410 PF07198.11 VBB26596.1 - 0.029 14.9 0.3 0.065 13.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) T3SS_needle_F PF09392.10 VBB26597.1 - 0.18 12.0 0.0 0.52 10.6 0.0 1.7 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF VWA_N PF08399.11 VBB26598.1 - 2.2e-29 102.5 0.4 2.2e-29 102.5 0.4 2.3 3 0 0 3 3 3 1 VWA N-terminal dCache_1 PF02743.18 VBB26598.1 - 4e-14 53.0 0.3 8.1e-10 38.9 0.1 2.6 2 0 0 2 2 2 2 Cache domain VWA PF00092.28 VBB26598.1 - 7.2e-13 49.2 0.6 8.6e-07 29.4 0.0 2.8 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 VBB26598.1 - 2.6e-08 33.9 0.0 2.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 VBB26598.1 - 8.2e-08 32.9 0.1 8.5e-07 29.6 0.1 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain PHTB1_N PF14727.6 VBB26598.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 PTHB1 N-terminus CobT_C PF11775.8 VBB26598.1 - 0.16 11.6 0.0 0.97 9.0 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain CPSF_A PF03178.15 VBB26599.1 - 6.4e-74 249.2 1.6 1.2e-73 248.3 0.6 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 VBB26599.1 - 9.2e-71 238.9 0.0 2.3e-70 237.6 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MBF1 PF08523.10 VBB26599.1 - 1.6e-19 70.1 0.7 3e-19 69.2 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 VBB26599.1 - 3.8e-11 42.9 0.1 9.6e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 VBB26599.1 - 4.6e-05 23.7 0.3 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 VBB26599.1 - 0.018 15.0 0.1 0.059 13.4 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain I-set PF07679.16 VBB26600.1 - 7.3e-58 192.6 0.0 1.7e-10 40.8 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB26600.1 - 1e-56 189.5 0.3 2.3e-10 40.9 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 VBB26600.1 - 7.5e-44 148.0 6.3 9.6e-11 41.9 0.3 5.4 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 VBB26600.1 - 5.2e-34 116.4 0.0 2.6e-06 27.7 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 VBB26600.1 - 6.7e-30 103.1 0.0 8.4e-09 35.5 0.0 6.5 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 VBB26600.1 - 5e-19 68.5 3.4 0.002 18.3 0.0 7.7 6 3 0 6 6 6 3 Immunoglobulin V-set domain Ig_4 PF16680.5 VBB26600.1 - 1.3e-05 25.3 0.1 0.23 11.8 0.0 4.3 5 0 0 5 5 4 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 VBB26600.1 - 1.6e-05 24.4 0.3 5.1 6.7 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB26600.1 - 0.0002 21.3 0.1 0.58 10.2 0.0 4.5 4 1 0 4 4 4 1 C17orf99 Ig domain Izumo-Ig PF16706.5 VBB26600.1 - 0.013 15.6 0.0 13 5.9 0.0 3.7 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 VBB26600.1 - 0.015 15.5 0.2 2.1 8.6 0.0 3.5 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 SET PF00856.28 VBB26601.1 - 1e-17 65.1 0.1 4.1e-17 63.1 0.1 2.1 2 1 0 2 2 2 1 SET domain EF-hand_1 PF00036.32 VBB26601.1 - 1.8e-07 30.2 2.5 0.0026 17.2 0.1 3.2 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 VBB26601.1 - 4.7e-07 29.0 0.3 0.0099 15.3 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 VBB26601.1 - 2.7e-06 27.7 0.3 0.11 12.9 0.0 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB26601.1 - 5.3e-06 26.0 3.1 0.021 14.7 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 VBB26601.1 - 1.1e-05 25.2 0.1 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair SH3_1 PF00018.28 VBB26602.1 - 9.9e-19 66.7 0.1 6.4e-15 54.5 0.1 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 VBB26602.1 - 1e-18 66.9 0.1 3.4e-11 42.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 VBB26602.1 - 5.7e-18 64.4 0.0 4.3e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 VBB26602.1 - 1.9e-12 47.1 0.0 1.3e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 SH2 domain hSH3 PF14603.6 VBB26602.1 - 0.025 15.0 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Helically-extended SH3 domain GLTSCR1 PF15249.6 VBB26603.1 - 8.6e-22 77.5 2.4 5.4e-21 75.0 1.5 3.0 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein LSM PF01423.22 VBB26604.1 - 0.0012 18.5 0.0 0.0068 16.1 0.0 2.1 1 1 0 1 1 1 1 LSM domain Kazal_3 PF18434.1 VBB26604.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Xpo1 PF08389.12 VBB26605.1 - 5.6e-05 23.2 11.4 0.00014 21.9 0.9 4.1 3 1 1 4 4 4 2 Exportin 1-like protein Xpo1 PF08389.12 VBB26606.1 - 6.6e-05 23.0 0.3 0.0036 17.4 0.0 2.2 2 0 0 2 2 2 2 Exportin 1-like protein AAA_25 PF13481.6 VBB26606.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-RING_4 PF14570.6 VBB26607.1 - 2.8e-19 68.6 13.4 7.4e-19 67.3 13.4 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 VBB26607.1 - 1.1e-06 28.3 8.4 2.7e-06 27.1 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 VBB26607.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 VBB26607.1 - 0.0029 17.9 10.9 0.012 15.9 10.9 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB26607.1 - 0.01 15.7 10.4 0.034 14.0 10.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 VBB26607.1 - 0.056 13.9 1.5 0.31 11.6 1.5 2.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-UDP PF14569.6 VBB26607.1 - 0.12 12.5 6.0 0.15 12.2 3.8 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zinc_ribbon_16 PF17034.5 VBB26607.1 - 2.2 8.5 9.0 0.7 10.1 0.6 3.8 4 0 0 4 4 4 0 Zinc-ribbon like family MRP-S24 PF14955.6 VBB26608.1 - 3.2e-48 163.1 0.1 3.8e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 zf-C3HC PF07967.13 VBB26609.1 - 5.7e-19 68.5 0.1 5.7e-19 68.5 0.1 3.3 3 1 0 3 3 3 1 C3HC zinc finger-like BIR PF00653.21 VBB26609.1 - 3.2e-05 24.5 4.0 0.062 14.0 1.8 2.8 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Rsm1 PF08600.10 VBB26609.1 - 0.003 17.7 13.6 0.04 14.1 4.1 3.6 2 2 0 2 2 2 2 Rsm1-like ArgoMid PF16487.5 VBB26609.1 - 0.16 12.3 0.8 0.96 9.8 0.3 2.4 2 0 0 2 2 2 0 Mid domain of argonaute Sgf11 PF08209.11 VBB26609.1 - 0.99 9.0 5.0 12 5.6 0.1 2.7 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) CortBP2 PF09727.9 VBB26610.1 - 3.5e-63 213.0 23.3 3.5e-63 213.0 23.3 2.5 3 0 0 3 3 3 1 Cortactin-binding protein-2 DUF4407 PF14362.6 VBB26610.1 - 0.00059 19.3 12.7 0.00059 19.3 12.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) DUF5423 PF17461.2 VBB26610.1 - 0.0031 16.4 2.8 0.0062 15.4 2.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5423) DUF4164 PF13747.6 VBB26610.1 - 0.013 15.7 2.8 0.013 15.7 2.8 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Shugoshin_N PF07558.11 VBB26610.1 - 0.12 12.3 2.0 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Fungal_TACC PF12709.7 VBB26610.1 - 1.5 9.3 13.6 2.1 8.8 0.2 3.6 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins LMBR1 PF04791.16 VBB26610.1 - 7 5.4 9.1 9.8 5.0 9.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ras PF00071.22 VBB26611.1 - 4.5e-31 107.7 0.2 1.3e-23 83.4 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 VBB26611.1 - 3.8e-20 72.3 0.1 1.3e-12 48.0 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB26611.1 - 1.9e-09 37.2 0.1 3e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 VBB26611.1 - 0.0029 16.5 0.2 0.056 12.3 0.0 2.1 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 VBB26611.1 - 0.013 14.9 0.3 0.31 10.3 0.0 2.2 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 VBB26611.1 - 0.03 14.6 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 VBB26611.1 - 0.032 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B FtsZ_C PF12327.8 VBB26611.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain AAA_18 PF13238.6 VBB26611.1 - 0.08 13.5 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ProRS-C_1 PF09180.11 VBB26611.1 - 0.097 12.9 0.1 7.9 6.8 0.0 2.6 2 1 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Methyltransf_25 PF13649.6 VBB26612.1 - 6.3e-06 26.8 1.0 3e-05 24.6 0.2 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB26612.1 - 1.8e-05 24.6 0.0 5.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 VBB26612.1 - 4.7e-05 23.2 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 VBB26612.1 - 9.2e-05 22.1 0.3 0.0003 20.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.20 VBB26612.1 - 0.00056 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 VBB26612.1 - 0.00063 20.4 0.3 0.002 18.8 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 VBB26612.1 - 0.0057 16.1 0.1 0.0098 15.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 VBB26612.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 VBB26612.1 - 0.051 14.3 0.1 0.19 12.5 0.1 2.0 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 VBB26612.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 VBB26612.1 - 0.33 10.9 1.4 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Carn_acyltransf PF00755.20 VBB26613.1 - 3.7e-139 465.0 0.0 1.8e-136 456.2 0.0 2.1 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF498 PF04430.14 VBB26613.1 - 7.9e-12 45.2 0.2 1.8e-09 37.6 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF498/DUF598) THEG PF14912.6 VBB26614.1 - 0.046 14.2 0.6 1.5 9.3 0.1 3.4 3 0 0 3 3 3 0 Testicular haploid expressed repeat SAP PF02037.27 VBB26614.1 - 0.076 12.8 1.9 0.084 12.6 0.1 2.1 2 0 0 2 2 2 0 SAP domain DUF2151 PF10221.9 VBB26615.1 - 1.7e-154 516.1 0.0 3.5e-154 515.1 0.0 1.4 1 1 0 1 1 1 1 Cell cycle and development regulator Hairy_orange PF07527.13 VBB26615.1 - 0.18 12.1 2.2 20 5.5 0.1 2.7 2 0 0 2 2 2 0 Hairy Orange zf-CCCH PF00642.24 VBB26616.1 - 3.6e-13 49.0 15.1 1.7e-06 27.8 1.5 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB26616.1 - 2.6e-06 27.3 14.7 0.00038 20.4 1.5 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 VBB26616.1 - 8.8e-06 25.5 0.2 7.1e-05 22.6 0.1 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 VBB26616.1 - 0.088 13.5 11.4 0.24 12.1 0.4 2.8 2 1 0 2 2 2 0 Torus domain START PF01852.19 VBB26617.1 - 3.4e-08 33.1 0.0 4.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 START domain AcylCoA_dehyd_C PF12186.8 VBB26617.1 - 0.042 14.0 1.0 6.9 6.8 0.0 2.6 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal RSB_motif PF16294.5 VBB26618.1 - 5.2e-20 71.6 8.8 5.2e-20 71.6 8.8 6.7 4 2 2 6 6 6 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 VBB26618.1 - 1.3e-12 47.2 0.7 4.1e-11 42.4 0.6 2.5 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 VBB26618.1 - 0.0086 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.23 VBB26619.1 - 8.1e-47 159.6 0.0 4e-46 157.4 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB26619.1 - 3e-15 56.5 0.0 8.2e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 VBB26619.1 - 2.1e-06 27.1 0.0 1.6e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 VBB26619.1 - 2.8e-06 27.5 0.0 1.6e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 VBB26619.1 - 0.00031 20.1 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 VBB26619.1 - 0.00034 20.4 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Rad54_N PF08658.10 VBB26619.1 - 0.0018 18.5 0.1 0.0036 17.5 0.1 1.5 1 0 0 1 1 1 1 Rad54 N terminal Hydrolase_6 PF13344.6 VBB26620.1 - 8.6e-28 96.4 0.0 2.2e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 VBB26620.1 - 4.4e-16 58.7 0.0 7.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 VBB26620.1 - 6.2e-11 43.0 0.0 0.00026 21.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 VBB26620.1 - 7.2e-08 32.7 0.1 0.0012 19.0 0.1 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Peripla_BP_4 PF13407.6 VBB26620.1 - 0.0051 16.4 0.0 1.8 8.1 0.0 2.8 1 1 2 3 3 3 2 Periplasmic binding protein domain PGP_phosphatase PF09419.10 VBB26620.1 - 0.051 13.2 0.0 0.33 10.5 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase P53_C PF11619.8 VBB26621.1 - 0.18 11.9 1.3 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain PCI PF01399.27 VBB26622.1 - 4.2e-18 65.8 0.1 2e-17 63.6 0.0 2.2 2 1 1 3 3 3 1 PCI domain RPN5_C PF18098.1 VBB26622.1 - 5.7e-10 39.1 0.7 1.6e-09 37.7 0.7 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain ERp29 PF07749.12 VBB26622.1 - 0.94 10.4 5.5 1.3 10.0 0.2 3.5 4 1 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain zf-UBR PF02207.20 VBB26623.1 - 2.6e-17 62.7 12.0 2.6e-17 62.7 12.0 2.5 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Aa_trans PF01490.18 VBB26626.1 - 1.4e-51 175.5 16.6 3e-39 134.9 10.6 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 VBB26626.1 - 3.8e-05 22.9 5.0 3.8e-05 22.9 5.0 2.7 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 VBB26626.1 - 0.005 15.7 3.5 0.005 15.7 3.5 2.8 2 1 0 2 2 2 2 Spore germination protein DUF1761 PF08570.10 VBB26626.1 - 0.023 15.0 0.1 0.023 15.0 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1761) Exonuc_VII_L PF02601.15 VBB26627.1 - 0.4 10.2 13.0 0.62 9.6 1.3 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit zf-RING_2 PF13639.6 VBB26628.1 - 6.9e-12 45.5 9.6 2e-11 44.1 9.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 VBB26628.1 - 1.9e-09 37.7 7.2 8.2e-09 35.6 7.2 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 VBB26628.1 - 1e-07 31.6 10.0 2.7e-07 30.3 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB26628.1 - 3.2e-06 27.1 2.9 7.6e-06 25.9 2.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 VBB26628.1 - 1.3e-05 25.0 7.5 2.8e-05 23.9 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB26628.1 - 2.9e-05 24.0 4.3 3.5e-05 23.7 2.8 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 VBB26628.1 - 3.7e-05 23.4 4.3 3.7e-05 23.4 4.3 2.3 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 VBB26628.1 - 3.8e-05 23.6 7.0 0.00012 22.0 7.1 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 VBB26628.1 - 0.00029 20.6 9.0 0.00072 19.4 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.12 VBB26628.1 - 0.00048 20.2 2.6 0.00048 20.2 2.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Lzipper-MIP1 PF14389.6 VBB26628.1 - 0.0065 16.8 1.3 0.0065 16.8 1.3 3.4 2 1 1 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Prok-RING_4 PF14447.6 VBB26628.1 - 0.0077 16.1 7.5 0.021 14.7 7.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 VBB26628.1 - 0.026 14.1 6.7 0.054 13.1 6.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 VBB26628.1 - 0.076 12.8 2.7 0.18 11.6 2.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 VBB26628.1 - 0.12 12.5 8.9 0.35 11.1 8.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 VBB26628.1 - 0.39 10.9 8.3 4.8 7.4 8.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Bcr-Abl_Oligo PF09036.10 VBB26628.1 - 0.69 10.0 4.9 0.89 9.6 1.5 2.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Pox_A_type_inc PF04508.12 VBB26628.1 - 2.1 8.3 7.3 0.75 9.8 2.6 2.9 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat FlgT_M PF16539.5 VBB26628.1 - 2.2 8.4 6.5 0.34 11.0 0.3 2.5 2 1 1 3 3 3 0 Flagellar assembly protein T, middle domain FliD_N PF02465.18 VBB26628.1 - 3.1 8.6 10.3 0.072 13.8 0.8 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.19 VBB26628.1 - 3.2 5.5 12.1 1.4 6.7 9.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 VBB26628.1 - 5.4 7.1 27.5 27 4.8 23.4 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 VBB26628.1 - 8.9 6.3 18.4 5.6 7.0 3.5 2.5 2 0 0 2 2 2 0 Laminin Domain II Snf7 PF03357.21 VBB26629.1 - 2.3e-27 95.7 13.1 3.6e-27 95.1 13.1 1.3 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 VBB26629.1 - 0.00082 19.0 13.8 0.0014 18.2 13.8 1.3 1 0 0 1 1 1 1 PspA/IM30 family DUF4032 PF13224.6 VBB26629.1 - 0.0097 15.8 1.8 0.021 14.7 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) DUF1192 PF06698.11 VBB26629.1 - 0.028 14.5 1.5 0.1 12.7 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF5596 PF18082.1 VBB26629.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) DUF5082 PF16888.5 VBB26629.1 - 0.13 12.5 5.5 0.3 11.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) RecX PF02631.16 VBB26629.1 - 0.14 12.6 11.5 2.6 8.5 0.1 2.6 1 1 1 2 2 2 0 RecX family GrpE PF01025.19 VBB26629.1 - 0.2 11.3 6.6 0.39 10.4 6.6 1.5 1 0 0 1 1 1 0 GrpE 3HCDH PF00725.22 VBB26629.1 - 0.22 12.2 2.0 0.74 10.5 0.1 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain FapA PF03961.13 VBB26629.1 - 7.1 5.1 11.0 8.6 4.8 9.5 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Collagen PF01391.18 VBB26630.1 - 1.2e-10 40.9 36.3 6e-09 35.5 36.3 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB26631.1 - 1.1e-18 66.7 70.3 3.1e-10 39.7 31.0 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB26632.1 - 3.1e-06 26.8 16.2 3.8e-06 26.6 16.2 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) LPAM_2 PF13627.6 VBB26632.1 - 0.011 15.5 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Pkinase_Tyr PF07714.17 VBB26636.1 - 6e-54 183.0 0.0 9.1e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB26636.1 - 4.9e-45 154.0 0.0 8.5e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Collagen PF01391.18 VBB26636.1 - 1.1e-21 76.3 72.1 3.1e-10 39.6 20.1 4.4 4 0 0 4 4 4 3 Collagen triple helix repeat (20 copies) Cyt-b5 PF00173.28 VBB26636.1 - 5.7e-18 64.8 0.0 1.6e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 VBB26636.1 - 1.1e-12 48.1 0.0 2.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 VBB26636.1 - 5.4e-09 36.7 0.0 2.1e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Glutaredoxin PF00462.24 VBB26636.1 - 6.9e-09 35.8 0.0 2.8e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 Glutaredoxin Col_cuticle_N PF01484.17 VBB26636.1 - 0.15 12.2 0.3 0.35 11.0 0.3 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain MBD_C PF14048.6 VBB26637.1 - 6.2e-22 78.1 0.0 1.5e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 VBB26637.1 - 3.6e-09 36.7 6.6 6.8e-09 35.8 2.5 2.8 2 1 0 2 2 2 1 p55-binding region of Methyl-CpG-binding domain proteins MBD DUF2564 PF10819.8 VBB26637.1 - 0.033 14.6 0.1 0.065 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) LRR_9 PF14580.6 VBB26638.1 - 8.1e-14 51.5 0.1 1.3e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 VBB26638.1 - 3.6e-12 46.3 10.6 4.5e-06 26.9 3.0 3.6 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 VBB26638.1 - 1.5e-10 40.6 8.2 2.2e-05 24.1 2.4 3.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 VBB26638.1 - 3.1e-05 23.7 6.3 0.37 11.0 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat SDA1 PF05285.12 VBB26638.1 - 0.81 9.0 18.0 1.1 8.6 18.0 1.2 1 0 0 1 1 1 0 SDA1 FCP1_C PF09309.10 VBB26638.1 - 7.6 6.3 15.6 10 5.9 15.6 1.2 1 0 0 1 1 1 0 FCP1, C-terminal LRR_1 PF00560.33 VBB26638.1 - 8.9 7.3 14.4 57 4.9 1.1 5.0 4 2 1 5 5 5 0 Leucine Rich Repeat WD40 PF00400.32 VBB26639.1 - 8.6e-16 58.1 7.7 7.4e-09 36.1 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB26639.1 - 4.8e-09 36.4 0.4 0.00014 22.1 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_19 PF14559.6 VBB26639.1 - 0.0018 18.8 0.0 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB26639.1 - 0.0047 16.7 3.6 3.6 7.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 VBB26639.1 - 0.017 14.3 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB26639.1 - 0.018 15.2 0.3 5.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 VBB26639.1 - 0.02 15.2 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-H2C2_5 PF13909.6 VBB26641.1 - 1.7e-08 34.0 47.6 0.0014 18.3 1.9 6.8 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 VBB26641.1 - 0.005 16.9 3.6 0.005 16.9 3.6 6.5 4 3 2 6 6 6 1 Zinc-finger zf-H2C2_2 PF13465.6 VBB26641.1 - 0.019 15.4 0.2 0.019 15.4 0.2 9.7 10 1 0 10 10 10 0 Zinc-finger double domain ARS2 PF04959.13 VBB26641.1 - 0.096 13.0 2.0 2.8 8.3 2.1 2.4 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 VBB26641.1 - 0.33 11.9 74.2 2.3 9.3 0.6 9.0 8 0 0 8 8 8 0 C2H2-type zinc finger LRR_8 PF13855.6 VBB26642.1 - 7.5e-12 44.8 5.3 6.6e-08 32.2 0.9 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 VBB26642.1 - 2.1e-09 37.5 13.7 1.5e-05 25.3 1.6 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB26642.1 - 0.00073 19.7 7.7 0.19 12.4 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 VBB26642.1 - 0.019 15.0 7.0 0.35 11.0 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 VBB26642.1 - 0.15 11.6 1.7 0.58 9.6 0.7 1.9 1 1 0 1 1 1 0 Leucine-rich repeat FAM176 PF14851.6 VBB26643.1 - 0.29 10.8 2.5 0.62 9.7 2.5 1.5 1 0 0 1 1 1 0 FAM176 family DUF2749 PF10907.8 VBB26645.1 - 0.095 12.9 2.6 0.12 12.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF677 PF05055.12 VBB26645.1 - 0.5 9.2 1.6 0.49 9.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_transf_20 PF00982.21 VBB26646.1 - 2.6e-75 253.9 4.0 2.7e-74 250.6 0.8 2.8 3 1 0 3 3 3 2 Glycosyltransferase family 20 T6PP_N PF18572.1 VBB26646.1 - 2.5e-34 117.1 0.3 7.5e-34 115.6 0.3 1.9 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Hydrolase_3 PF08282.12 VBB26646.1 - 0.0049 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMEM156 PF15106.6 VBB26646.1 - 0.089 12.2 0.4 0.28 10.6 0.4 1.8 1 0 0 1 1 1 0 TMEM156 protein family MFS_1 PF07690.16 VBB26647.1 - 4.8e-55 186.9 25.2 4.8e-55 186.9 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3188 PF11384.8 VBB26647.1 - 0.083 12.6 0.7 0.63 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) EF-hand_6 PF13405.6 VBB26648.1 - 2.3e-13 48.9 1.5 1.7e-06 27.5 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 VBB26648.1 - 6.7e-13 48.9 0.1 1.8e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB26648.1 - 1.4e-10 39.9 4.9 6.9e-06 25.2 1.5 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 VBB26648.1 - 4.4e-07 29.6 0.4 0.0048 16.7 0.1 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB26648.1 - 6.5e-05 22.2 10.5 0.00034 20.0 1.0 3.4 2 1 0 2 2 2 1 EF hand UPF0154 PF03672.13 VBB26648.1 - 0.0014 18.6 0.8 0.019 15.0 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 VBB26648.1 - 0.0033 17.7 0.5 0.0091 16.3 0.3 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 VBB26648.1 - 0.0043 17.9 0.0 3 8.8 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain POTRA PF07244.15 VBB26648.1 - 0.012 16.1 0.5 1.1 9.9 0.0 2.5 3 0 0 3 3 3 0 Surface antigen variable number repeat SurA_N_2 PF13623.6 VBB26648.1 - 0.012 15.4 0.6 0.63 9.9 0.2 2.3 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_9 PF14658.6 VBB26648.1 - 0.038 14.3 0.0 4.2 7.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Adenine_glyco PF03352.13 VBB26648.1 - 0.074 12.8 0.1 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Methyladenine glycosylase SurA_N_3 PF13624.6 VBB26648.1 - 0.095 12.5 1.3 1.4 8.7 0.7 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF4612 PF15389.6 VBB26649.1 - 1.4e-08 35.8 0.3 2.8e-08 34.8 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4612) SGTA_dimer PF16546.5 VBB26649.1 - 0.041 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Homodimerisation domain of SGTA tRNA-synt_2b PF00587.25 VBB26651.1 - 2.4e-35 122.1 0.0 4.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 VBB26651.1 - 5.4e-19 68.2 0.5 1.7e-18 66.6 0.5 1.9 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 VBB26651.1 - 2e-14 53.3 0.0 4.8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 VBB26651.1 - 3.3e-11 43.1 0.1 7.2e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Phage_Mu_Gam PF07352.12 VBB26651.1 - 0.44 10.4 6.8 1.2 9.0 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Voltage_CLC PF00654.20 VBB26653.1 - 1.9e-93 313.6 22.8 1.9e-93 313.6 22.8 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 VBB26653.1 - 3.1e-14 53.2 0.1 2.8e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain FXMR_C2 PF16098.5 VBB26653.1 - 0.36 11.4 0.9 0.63 10.6 0.9 1.3 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 NYD-SP28 PF14772.6 VBB26653.1 - 0.41 10.7 6.0 0.64 10.1 6.0 1.3 1 0 0 1 1 1 0 Sperm tail eRF1_3 PF03465.15 VBB26654.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 3 DUF1242 PF06842.12 VBB26654.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1242) Syntaxin_2 PF14523.6 VBB26654.1 - 0.47 10.8 5.0 1.1 9.7 0.2 2.8 1 1 1 2 2 2 0 Syntaxin-like protein FliD_N PF02465.18 VBB26654.1 - 3.3 8.4 10.1 1.4 9.7 0.3 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Helicase_C PF00271.31 VBB26656.1 - 9e-05 22.8 0.1 0.00028 21.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB26656.1 - 0.00015 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2529 PF10740.9 VBB26656.1 - 0.041 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DNA_pol_B PF00136.21 VBB26657.1 - 2.9e-96 323.0 0.0 4.2e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 VBB26657.1 - 6.4e-26 91.3 4.1 5.7e-13 48.7 0.9 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 VBB26657.1 - 0.21 12.1 8.2 0.57 10.7 8.2 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Rhodanese_C PF12368.8 VBB26657.1 - 6.9 7.1 5.9 12 6.3 2.6 2.5 1 1 1 2 2 2 0 Rhodanase C-terminal ArfGap PF01412.18 VBB26658.1 - 1.6e-24 86.2 0.1 4.7e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SH3_9 PF14604.6 VBB26658.1 - 4.5e-10 39.2 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 VBB26658.1 - 5.9e-09 36.4 0.8 1.4e-08 35.1 0.8 1.7 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 VBB26658.1 - 2e-07 30.6 0.0 6.5e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB26658.1 - 3.5e-07 29.7 0.1 8.9e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain Med10 PF09748.9 VBB26658.1 - 0.1 12.6 2.0 0.23 11.4 0.6 2.2 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Asp_Arg_Hydrox PF05118.15 VBB26659.1 - 1.5e-37 128.9 0.1 2.8e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_16 PF13432.6 VBB26659.1 - 1.4e-09 38.4 0.4 7.4e-05 23.3 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB26659.1 - 4.2e-09 35.8 1.1 0.011 15.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB26659.1 - 5e-09 35.9 0.1 0.54 10.8 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB26659.1 - 8.9e-09 35.5 0.1 0.0042 17.8 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB26659.1 - 1.3e-08 34.3 0.1 0.56 10.6 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB26659.1 - 2.6e-07 31.0 0.0 0.021 15.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB26659.1 - 4.2e-06 26.9 0.2 0.00049 20.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB26659.1 - 9e-06 25.3 0.1 0.014 15.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 VBB26659.1 - 2.7e-05 24.5 0.8 0.48 11.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB26659.1 - 8.6e-05 22.7 0.1 0.84 9.9 0.1 2.8 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 VBB26659.1 - 0.015 15.0 6.4 0.47 10.2 0.1 4.4 5 0 0 5 5 5 0 TPR repeat TPR_9 PF13371.6 VBB26659.1 - 0.04 14.1 0.9 7.1 6.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_membrane PF00664.23 VBB26660.1 - 1.9e-54 185.2 41.4 9e-36 123.9 19.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 VBB26660.1 - 3.7e-44 150.6 0.0 2.2e-27 96.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 VBB26660.1 - 1.4e-08 34.5 5.7 0.031 13.7 0.5 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 VBB26660.1 - 5.2e-06 26.1 0.1 0.033 13.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DEAD PF00270.29 VBB26660.1 - 1.1e-05 25.3 1.6 0.0025 17.6 0.2 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_21 PF13304.6 VBB26660.1 - 0.0003 20.7 3.2 0.83 9.4 0.1 3.9 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 VBB26660.1 - 0.00035 21.1 2.0 0.19 12.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 VBB26660.1 - 0.00043 20.6 1.2 1.3 9.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 VBB26660.1 - 0.00067 19.7 0.6 0.44 10.6 0.2 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 VBB26660.1 - 0.0031 17.3 0.6 0.65 9.7 0.0 3.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 VBB26660.1 - 0.0031 16.6 0.1 0.18 10.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.15 VBB26660.1 - 0.0033 17.4 0.0 0.0087 16.0 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 VBB26660.1 - 0.006 15.8 0.2 0.6 9.3 0.1 2.7 2 1 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 VBB26660.1 - 0.007 16.9 0.9 1 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 VBB26660.1 - 0.013 15.4 0.1 7.8 6.4 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 VBB26660.1 - 0.013 15.9 0.1 1.1 9.6 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 VBB26660.1 - 0.014 15.5 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 VBB26660.1 - 0.017 15.5 0.0 3.5 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 VBB26660.1 - 0.02 14.5 2.0 0.31 10.6 0.1 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 VBB26660.1 - 0.027 14.7 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 VBB26660.1 - 0.027 14.2 3.0 2.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 VBB26660.1 - 0.031 14.0 0.6 4 7.1 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 VBB26660.1 - 0.041 14.2 0.2 1.5 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 VBB26660.1 - 0.051 13.7 0.1 0.95 9.5 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 VBB26660.1 - 0.057 13.3 0.1 2 8.3 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MobB PF03205.14 VBB26660.1 - 0.058 13.3 0.3 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 VBB26660.1 - 0.099 12.6 0.1 9.4 6.3 0.0 2.8 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 VBB26660.1 - 1.1 9.3 4.7 8.1 6.5 0.2 3.2 3 1 0 3 3 3 0 Dynamin family PAP2 PF01569.21 VBB26662.1 - 4.1e-20 71.9 0.6 7.6e-20 71.1 0.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 VBB26662.1 - 4.4e-05 23.3 5.1 0.00016 21.4 5.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 VBB26662.1 - 0.045 14.3 0.4 0.045 14.3 0.4 2.3 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Slu7 PF11708.8 VBB26663.1 - 7.3e-99 330.9 9.9 7.3e-99 330.9 9.9 3.5 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor DSBA PF01323.20 VBB26663.1 - 0.082 12.7 0.2 0.27 11.0 0.2 1.9 1 0 0 1 1 1 0 DSBA-like thioredoxin domain zf-CCHC_4 PF14392.6 VBB26663.1 - 0.091 12.5 0.5 0.2 11.4 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 VBB26663.1 - 0.2 11.8 3.2 0.38 10.9 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Pneumo_att_G PF05539.11 VBB26663.1 - 6.9 6.2 7.9 11 5.5 7.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RNase_PH PF01138.21 VBB26664.1 - 3.9e-35 121.2 0.0 2e-34 118.9 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 KH_6 PF15985.5 VBB26665.1 - 5.4e-14 52.3 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 VBB26665.1 - 1.3e-13 50.5 0.0 2.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 VBB26665.1 - 0.0024 18.5 4.3 0.14 12.8 0.1 2.9 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 Thymopoietin PF08198.11 VBB26665.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Thymopoietin protein Glucosamine_iso PF01182.20 VBB26666.1 - 1.3e-63 214.9 0.0 1.5e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SEA PF01390.20 VBB26667.1 - 6.3e-08 32.7 0.0 7.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 SEA domain Arrestin_N PF00339.29 VBB26668.1 - 1.3e-37 129.1 0.0 1.8e-33 115.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 VBB26668.1 - 7.1e-34 117.2 0.1 1.1e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain zf-C2H2 PF00096.26 VBB26669.1 - 5.7e-19 67.4 53.9 0.00073 19.9 2.1 8.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26669.1 - 7.1e-13 48.2 50.4 0.13 13.1 1.2 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 VBB26669.1 - 9.3e-09 34.9 15.9 3.6e-05 23.4 0.4 5.0 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-met PF12874.7 VBB26669.1 - 5.9e-08 32.9 48.2 0.0085 16.5 0.6 9.1 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB26669.1 - 5.2e-07 29.8 41.7 0.11 12.8 0.2 8.7 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 VBB26669.1 - 3e-06 27.4 23.7 0.15 12.3 0.3 5.9 5 0 0 5 5 5 4 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 VBB26669.1 - 1.6e-05 24.4 13.1 0.11 12.1 0.1 5.6 5 0 0 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 VBB26669.1 - 0.0041 17.4 3.9 0.0041 17.4 3.9 6.9 4 3 2 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 VBB26669.1 - 0.022 15.2 1.4 0.022 15.2 1.4 6.2 10 0 0 10 10 6 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 VBB26669.1 - 0.03 14.3 0.0 0.03 14.3 0.0 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 VBB26669.1 - 0.26 11.4 15.2 0.042 14.0 1.7 4.3 4 1 1 5 5 5 0 Aberrant zinc-finger PepSY_2 PF13670.6 VBB26669.1 - 8.4 6.5 9.1 40 4.3 9.1 2.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain PAN_1 PF00024.26 VBB26672.1 - 5.6e-17 61.5 12.1 2.5e-09 37.0 0.7 3.4 3 0 0 3 3 3 3 PAN domain DUF1540 PF07561.11 VBB26672.1 - 0.064 13.6 0.4 0.25 11.7 0.4 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) Desulfoferrodox PF01880.18 VBB26672.1 - 0.095 13.3 0.1 1.6 9.4 0.0 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin Pro_isomerase PF00160.21 VBB26673.1 - 3.8e-40 137.7 0.0 6.2e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RsfS PF02410.15 VBB26673.1 - 3.1e-18 66.0 0.1 6.1e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DSPc PF00782.20 VBB26674.1 - 2.1e-30 105.3 0.0 2.6e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB26674.1 - 0.0035 16.9 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cg6151-P PF10233.9 VBB26674.1 - 0.082 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Peptidase_C2 PF00648.21 VBB26675.1 - 2.7e-109 364.8 0.6 3.6e-109 364.4 0.6 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 VBB26675.1 - 2.5e-21 76.4 0.1 6.6e-21 75.1 0.1 1.7 2 0 0 2 2 2 1 Calpain large subunit, domain III TSP_1 PF00090.19 VBB26676.1 - 2.7e-09 37.1 3.9 5.3e-09 36.2 3.9 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain DUF2854 PF11016.8 VBB26677.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Folliculin_C PF16692.5 VBB26678.1 - 6.9e-65 218.9 0.2 1.3e-64 218.0 0.2 1.5 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 VBB26678.1 - 2.1e-45 154.9 0.5 3.1e-45 154.3 0.5 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport eIF-3_zeta PF05091.12 VBB26679.1 - 2.5e-193 643.8 0.1 2.9e-193 643.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 VBB26679.1 - 0.0031 17.1 0.0 0.0087 15.6 0.0 1.7 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus DUF3394 PF11874.8 VBB26680.1 - 0.0071 16.0 3.7 1.9 8.2 0.5 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3394) BTB PF00651.31 VBB26681.1 - 2.5e-10 40.6 0.7 2.2e-07 31.1 0.2 2.8 2 1 0 2 2 2 2 BTB/POZ domain WD40 PF00400.32 VBB26682.1 - 2.9e-44 148.2 23.3 5.5e-07 30.2 0.2 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat Utp12 PF04003.12 VBB26682.1 - 1.1e-18 67.5 0.0 2.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 VBB26682.1 - 2.2e-18 66.4 4.9 0.021 15.1 0.0 8.8 3 2 8 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB26682.1 - 2.3e-09 37.0 3.0 0.039 13.3 0.1 4.7 3 1 2 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 VBB26682.1 - 8.1e-05 21.7 1.7 0.92 8.4 0.0 5.2 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 VBB26682.1 - 0.0012 18.9 0.9 3.1 7.9 0.0 4.9 5 1 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Sec23_helical PF04815.15 VBB26682.1 - 0.076 12.8 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Sec23/Sec24 helical domain BPL_LplA_LipB PF03099.19 VBB26683.1 - 7.4e-14 51.8 0.0 2.1e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 VBB26683.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Inhibitor_I10 PF12559.8 VBB26683.1 - 0.032 14.5 0.2 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Serine endopeptidase inhibitors NDUF_B5 PF09781.9 VBB26684.1 - 4.7e-16 58.9 0.3 3.1e-15 56.2 0.3 2.0 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit TTR-52 PF01060.23 VBB26684.1 - 3.9e-11 43.5 0.0 1.2e-10 41.9 0.0 1.8 1 1 0 1 1 1 1 Transthyretin-like family TAD2 PF18521.1 VBB26684.1 - 0.028 14.4 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Transactivation domain 2 Tub PF01167.18 VBB26685.1 - 7.8e-87 291.0 0.0 1e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 VBB26685.1 - 0.002 17.8 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) Methyltransf_11 PF08241.12 VBB26686.1 - 9.3e-16 58.3 0.0 3.2e-15 56.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB26686.1 - 7.4e-14 52.2 0.1 3.8e-13 50.0 0.1 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB26686.1 - 1.4e-10 40.9 0.0 2.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 VBB26686.1 - 5.8e-10 39.2 0.4 2e-09 37.4 0.1 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB26686.1 - 1.6e-09 37.8 0.0 3.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB26686.1 - 1.7e-08 35.1 0.1 1.3e-07 32.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 VBB26686.1 - 4.1e-08 32.9 0.0 1.5e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 VBB26686.1 - 0.001 18.5 0.0 0.0043 16.5 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB NodS PF05401.11 VBB26686.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 VBB26686.1 - 0.015 15.1 0.3 0.07 13.0 0.0 2.2 3 0 0 3 3 3 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 VBB26686.1 - 0.028 13.6 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 VBB26686.1 - 0.03 13.8 0.2 0.13 11.7 0.2 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_29 PF03141.16 VBB26686.1 - 0.069 11.7 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RPA_C PF08784.11 VBB26686.1 - 0.16 12.6 0.0 0.37 11.5 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal DUF2250 PF10007.9 VBB26686.1 - 0.35 11.0 1.4 2.1 8.5 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) TMEM43 PF07787.12 VBB26687.1 - 1.1 8.6 5.3 1.5 8.1 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 ubiquitin PF00240.23 VBB26688.1 - 3e-09 36.5 0.0 6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CysG_dimeriser PF10414.9 VBB26688.1 - 0.0085 15.8 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region EST1_DNA_bind PF10373.9 VBB26689.1 - 1.3e-31 110.2 0.1 4.6e-31 108.3 0.1 2.1 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 VBB26689.1 - 6.1e-17 62.1 1.7 7.7e-16 58.6 0.0 3.0 2 0 0 2 2 2 1 PIN domain EST1 PF10374.9 VBB26689.1 - 1.6e-08 35.2 3.5 1.9e-08 35.0 0.0 3.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 PDEase_I PF00233.19 VBB26691.1 - 3.8e-36 125.0 6.4 8e-36 123.9 6.4 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 VBB26691.1 - 7.7e-14 52.5 0.0 1.7e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 VBB26691.1 - 1.6e-08 34.9 0.0 4.4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 VBB26691.1 - 7.9e-06 26.2 0.0 2.3e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain EF-hand_5 PF13202.6 VBB26692.1 - 0.00029 20.2 0.9 0.1 12.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 VBB26692.1 - 0.0025 17.2 0.4 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 VBB26692.1 - 0.0031 17.9 0.2 0.022 15.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB26692.1 - 0.046 13.7 0.5 0.98 9.5 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 VBB26692.1 - 0.061 13.2 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair GCV_H PF01597.19 VBB26693.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein GPCR_chapero_1 PF11904.8 VBB26694.1 - 2.1e-66 224.5 1.2 3.2e-66 223.9 1.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 VBB26694.1 - 2.3e-10 40.9 0.1 5.4e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB26694.1 - 2.8e-07 30.9 0.8 0.0068 17.0 0.5 3.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB26694.1 - 3.3e-07 30.1 0.1 1.8 9.4 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 VBB26694.1 - 2.2e-06 27.9 0.3 0.21 12.1 0.2 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 VBB26694.1 - 0.0041 17.4 0.1 0.014 15.7 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SdiA-regulated PF06977.11 VBB26694.1 - 0.01 15.1 0.2 0.25 10.5 0.0 2.2 1 1 1 2 2 2 0 SdiA-regulated Cytochrom_C_asm PF01578.20 VBB26695.1 - 0.016 15.0 0.2 0.017 14.9 0.2 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein MAP17 PF15807.5 VBB26695.1 - 0.042 14.1 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MFS_1 PF07690.16 VBB26696.1 - 1.2e-24 86.9 46.5 4.5e-23 81.7 37.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 VBB26697.1 - 6.5e-139 461.7 0.0 2.7e-74 249.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26697.1 - 2.3e-62 210.6 0.0 4.6e-32 111.3 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 VBB26697.1 - 8.5e-09 35.1 0.1 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 VBB26697.1 - 7.7e-08 31.7 0.2 1.3e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 VBB26697.1 - 5.2e-06 26.6 0.0 0.0089 16.0 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 VBB26697.1 - 6.3e-05 22.2 0.0 0.053 12.6 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 Kdo PF06293.14 VBB26697.1 - 6.8e-05 22.3 1.4 0.0017 17.7 0.1 2.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 VBB26697.1 - 0.00035 20.2 0.3 0.0035 17.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 VBB26697.1 - 0.025 14.2 0.1 2.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 VBB26697.1 - 0.15 11.6 0.2 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase TMEM72 PF16054.5 VBB26697.1 - 0.23 11.1 0.5 8 6.1 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein family 72 Methyltransf_4 PF02390.17 VBB26698.1 - 9.8e-58 194.4 0.0 1.3e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase zf-CDGSH PF09360.10 VBB26698.1 - 9.7e-10 38.5 0.1 3.2e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Methyltransf_25 PF13649.6 VBB26698.1 - 0.0065 17.1 0.0 0.029 15.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 VBB26698.1 - 0.007 15.9 0.0 0.046 13.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 VBB26698.1 - 0.15 12.8 0.0 2.4 8.9 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 VBB26698.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 VBB26698.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.20 VBB26699.1 - 1.7e-109 366.7 0.6 2.1e-109 366.4 0.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 VBB26699.1 - 2.5e-15 56.1 1.2 2.5e-15 56.1 1.2 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Raco_middle PF17651.1 VBB26699.1 - 0.0016 18.1 1.0 0.042 13.5 0.0 2.9 3 0 0 3 3 3 1 RACo middle region Actin PF00022.19 VBB26699.1 - 0.0037 16.0 0.0 0.56 8.7 0.0 2.3 2 0 0 2 2 2 2 Actin StbA PF06406.11 VBB26699.1 - 0.0054 16.0 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 StbA protein FtsA PF14450.6 VBB26699.1 - 0.036 14.5 0.9 1.5 9.3 0.0 2.9 2 2 0 2 2 2 0 Cell division protein FtsA Humanin PF15040.6 VBB26699.1 - 0.047 13.1 0.3 0.38 10.2 0.1 2.5 2 0 0 2 2 2 0 Humanin family Metallophos PF00149.28 VBB26700.1 - 3e-25 89.9 0.0 5.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB26700.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain AdoHcyase_NAD PF00670.21 VBB26701.1 - 0.029 14.4 0.4 0.044 13.8 0.4 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CybS PF05328.12 VBB26702.1 - 3.7e-24 84.9 0.2 4.4e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit FAD_binding_1 PF00667.20 VBB26703.1 - 2e-28 99.5 0.0 3.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 VBB26703.1 - 9.2e-08 32.7 0.0 1.7e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Init_tRNA_PT PF04179.12 VBB26703.1 - 0.089 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Serpin PF00079.20 VBB26705.1 - 2.2e-54 185.2 1.4 7.4e-39 134.1 0.5 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) 7tm_1 PF00001.21 VBB26706.1 - 4.1e-38 131.2 22.4 5.5e-38 130.8 22.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB26706.1 - 0.0041 16.8 12.8 0.0041 16.8 12.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx OATP PF03137.20 VBB26707.1 - 3.9e-141 471.0 19.1 5.2e-141 470.6 19.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 VBB26707.1 - 5.4e-11 42.0 33.3 2.2e-10 40.0 9.2 3.5 3 1 1 4 4 4 2 Major Facilitator Superfamily Kazal_2 PF07648.15 VBB26707.1 - 0.028 14.5 9.8 0.086 13.0 9.8 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF2464 PF10240.9 VBB26709.1 - 3e-69 233.4 0.3 3.5e-69 233.3 0.3 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 RPAP1_N PF08621.10 VBB26710.1 - 4.5e-14 51.9 9.0 4.5e-14 51.9 9.0 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal Claudin_2 PF13903.6 VBB26710.1 - 0.041 13.6 0.3 0.094 12.5 0.3 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IPP-2 PF04979.14 VBB26710.1 - 0.15 12.8 18.4 0.096 13.4 11.5 3.6 2 1 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) CCDC24 PF15669.5 VBB26710.1 - 0.51 10.2 7.4 2.5 7.9 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family eIF3_N PF09440.10 VBB26710.1 - 4.8 7.6 9.5 6.6 7.2 1.0 2.6 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain ShK PF01549.24 VBB26712.1 - 6e-11 42.7 82.2 0.01 16.4 8.0 5.4 5 0 0 5 5 5 5 ShK domain-like Transposase_20 PF02371.16 VBB26712.1 - 0.14 12.5 0.2 0.58 10.5 0.1 2.1 1 1 1 2 2 2 0 Transposase IS116/IS110/IS902 family TUDOR PF00567.24 VBB26713.1 - 3.6e-18 65.8 0.0 2.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Tudor domain DUF3511 PF12023.8 VBB26713.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) eRF1_1 PF03463.15 VBB26714.1 - 1e-35 122.6 0.0 1.6e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 VBB26714.1 - 8.4e-29 100.6 0.2 1.8e-28 99.5 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 VBB26714.1 - 1.3e-20 74.0 0.1 1.1e-19 70.9 0.1 2.4 1 1 0 1 1 1 1 eRF1 domain 3 Cue1_U7BR PF18499.1 VBB26714.1 - 0.0052 16.8 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 1 Ubc7p-binding region of Cue1 bZIP_1 PF00170.21 VBB26715.1 - 1.7e-10 40.9 14.5 3.2e-10 40.0 14.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 VBB26715.1 - 1.7e-05 24.8 15.0 1.7e-05 24.8 15.0 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 VBB26715.1 - 0.00023 21.6 14.1 0.00049 20.6 14.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor UPF0449 PF15136.6 VBB26715.1 - 0.65 10.5 3.7 1.6 9.2 3.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 ZapB PF06005.12 VBB26715.1 - 0.78 10.2 13.4 0.051 14.0 4.8 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DnaJ PF00226.31 VBB26716.1 - 2.3e-28 98.1 1.8 5.7e-28 96.8 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain IMS_HHH PF11798.8 VBB26716.1 - 0.06 13.7 0.2 0.19 12.1 0.2 1.9 1 0 0 1 1 1 0 IMS family HHH motif FadA PF09403.10 VBB26716.1 - 2.7 8.5 9.3 0.41 11.2 4.1 2.2 2 1 0 2 2 2 0 Adhesion protein FadA Brix PF04427.18 VBB26717.1 - 6.7e-39 134.0 1.5 1.4e-38 132.9 1.5 1.6 1 0 0 1 1 1 1 Brix domain AP3D1 PF06375.11 VBB26717.1 - 0.85 9.9 9.5 0.089 13.0 4.7 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Phospho_p8 PF10195.9 VBB26718.1 - 3.8e-15 56.1 5.0 4.6e-15 55.9 5.0 1.1 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 PcfK PF14058.6 VBB26719.1 - 0.01 16.1 5.7 0.19 12.0 0.2 2.8 2 0 0 2 2 2 0 PcfK-like protein HTH_29 PF13551.6 VBB26719.1 - 0.49 10.5 1.8 0.7 9.9 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Pkinase PF00069.25 VBB26720.1 - 3.7e-17 62.6 0.1 7.1e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I PF08311.12 VBB26720.1 - 3.8e-07 30.1 1.1 7.9e-07 29.1 1.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.17 VBB26720.1 - 1.5e-06 27.7 0.0 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB26720.1 - 0.021 13.6 0.1 0.044 12.6 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase TSP_1 PF00090.19 VBB26720.1 - 0.05 13.8 0.9 0.21 11.9 0.9 2.1 1 0 0 1 1 1 0 Thrombospondin type 1 domain FSA_C PF10479.9 VBB26721.1 - 0.085 11.0 18.5 0.085 11.0 18.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HEXIM PF15313.6 VBB26722.1 - 0.41 10.8 2.4 0.46 10.7 0.4 1.9 1 1 1 2 2 2 0 Hexamethylene bis-acetamide-inducible protein zf-C2H2_4 PF13894.6 VBB26722.1 - 0.71 10.9 5.6 0.72 10.9 1.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger 7TM_GPCR_Srx PF10328.9 VBB26723.1 - 2.6e-24 86.3 8.1 1.8e-15 57.3 2.1 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx TM231 PF10149.9 VBB26723.1 - 0.031 13.6 0.6 0.041 13.2 0.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 7tm_1 PF00001.21 VBB26723.1 - 0.08 12.2 5.1 0.3 10.4 5.1 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) BAR PF03114.18 VBB26724.1 - 8.2e-11 42.0 2.5 1e-10 41.7 2.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 VBB26724.1 - 0.04 13.0 2.0 0.05 12.7 0.3 1.7 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Hrs_helical PF12210.8 VBB26724.1 - 2.4 8.8 7.0 4.6 7.8 0.0 3.1 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Peptidase_M13_N PF05649.13 VBB26725.1 - 4.5e-85 286.6 0.5 6e-85 286.2 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 VBB26725.1 - 9.5e-65 218.0 0.2 2.2e-64 216.9 0.2 1.7 1 0 0 1 1 1 1 Peptidase family M13 EMP24_GP25L PF01105.24 VBB26725.1 - 0.093 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glyco_transf_22 PF03901.17 VBB26727.1 - 7.2e-45 154.0 27.2 8.3e-45 153.8 27.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family tRNA-synt_1 PF00133.22 VBB26728.1 - 2.4e-126 422.4 0.0 4.3e-124 415.0 0.0 3.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_2d PF01409.20 VBB26728.1 - 5.8e-49 166.8 0.7 7.3e-31 107.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Anticodon_1 PF08264.13 VBB26728.1 - 1.2e-16 61.0 3.0 1.4e-13 51.1 0.3 2.6 1 1 1 2 2 2 2 Anticodon-binding domain of tRNA FDX-ACB PF03147.14 VBB26728.1 - 1e-11 45.1 0.0 4.1e-11 43.2 0.0 2.1 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_1g PF09334.11 VBB26728.1 - 3.4e-06 26.1 0.1 0.06 12.1 0.0 3.0 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 VBB26728.1 - 5.7e-06 26.0 0.0 0.00018 21.0 0.0 2.9 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 DUF2203 PF09969.9 VBB26728.1 - 0.12 13.0 2.1 0.35 11.6 2.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) tRNA-synt_1b PF00579.25 VBB26728.1 - 1.4 8.2 3.4 1.3 8.3 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) CelTOS PF18659.1 VBB26728.1 - 1.6 9.2 6.4 6.9 7.1 0.5 3.2 4 0 0 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites RRM_1 PF00076.22 VBB26730.1 - 2.7e-85 280.2 1.8 4.1e-17 61.8 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB26730.1 - 4.4e-08 33.1 0.5 0.2 11.7 0.0 6.4 6 1 0 7 7 7 2 RNA binding motif RRM_occluded PF16842.5 VBB26730.1 - 1.4e-07 31.3 0.0 0.012 15.4 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 VBB26730.1 - 1.6e-07 31.2 0.2 0.0038 17.2 0.0 4.7 6 0 0 6 6 6 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 VBB26730.1 - 5.5e-05 23.2 0.0 0.95 9.6 0.0 4.7 5 0 0 5 5 5 2 RNA recognition motif Spaetzle PF16077.5 VBB26731.1 - 0.11 13.0 0.6 0.37 11.3 0.0 2.0 2 1 0 2 2 2 0 Spaetzle PAN_1 PF00024.26 VBB26732.1 - 0.00013 21.8 3.7 0.0002 21.2 3.7 1.4 1 0 0 1 1 1 1 PAN domain Collagen PF01391.18 VBB26733.1 - 4.9e-23 80.6 97.9 8.2e-10 38.3 32.4 4.7 3 1 1 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26733.1 - 4.9e-19 68.1 2.7 7.4e-19 67.6 2.7 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain HEAT PF02985.22 VBB26733.1 - 0.01 16.0 0.0 4.7 7.7 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat TDP43_N PF18694.1 VBB26734.1 - 4.9e-18 64.7 0.0 1.1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain Fib_alpha PF08702.10 VBB26734.1 - 0.013 15.7 2.7 0.013 15.7 2.7 4.1 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 VBB26734.1 - 1.7 8.8 34.0 3.5 7.8 11.7 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 VBB26734.1 - 1.8 9.3 21.7 2.6 8.7 2.3 4.9 4 1 1 5 5 5 0 SlyX NPV_P10 PF05531.12 VBB26734.1 - 3.6 8.1 12.5 0.085 13.3 1.6 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 VBB26734.1 - 8 7.2 21.1 1.2 9.9 5.2 3.8 1 1 2 3 3 3 0 Initiation control protein YabA OAD_gamma PF04277.13 VBB26735.1 - 0.13 12.9 0.1 0.13 12.9 0.1 2.1 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1241 PF06840.11 VBB26736.1 - 1.4e-48 164.3 0.8 2e-48 163.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Potyvirid-P3 PF13608.6 VBB26736.1 - 0.0032 16.6 1.4 0.0056 15.8 1.4 1.4 1 1 0 1 1 1 1 Protein P3 of Potyviral polyprotein ECH_2 PF16113.5 VBB26736.1 - 0.016 14.7 0.5 0.025 14.1 0.5 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Focal_AT PF03623.13 VBB26736.1 - 0.038 14.0 1.9 0.11 12.4 0.8 2.1 1 1 1 2 2 2 0 Focal adhesion targeting region Pkinase PF00069.25 VBB26737.1 - 5.9e-34 117.6 0.0 6.6e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26737.1 - 4.9e-17 62.1 0.0 6e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB26737.1 - 4.7e-08 32.7 0.0 5.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB26737.1 - 0.0018 17.3 0.1 0.0027 16.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain HCO3_cotransp PF00955.21 VBB26738.1 - 4.5e-159 530.5 10.3 7.6e-159 529.8 10.3 1.3 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 VBB26738.1 - 0.00019 21.3 0.0 0.00043 20.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 VBB26738.1 - 0.00054 19.9 1.8 0.3 10.8 0.1 2.5 2 0 0 2 2 2 2 Band 3 cytoplasmic domain Peptidase_C2 PF00648.21 VBB26740.1 - 2.5e-61 207.3 0.2 6e-42 143.7 0.0 2.1 1 1 0 2 2 2 2 Calpain family cysteine protease zf-RanBP PF00641.18 VBB26740.1 - 0.3 10.4 3.4 0.79 9.1 3.4 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Myb_DNA-binding PF00249.31 VBB26742.1 - 1.8e-13 50.5 0.0 2e-07 31.1 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 VBB26742.1 - 5.1e-10 39.1 7.7 8.9e-07 28.7 1.0 2.7 2 0 0 2 2 2 2 Myb DNA-binding like ELM2 PF01448.24 VBB26742.1 - 2.3e-05 25.0 0.2 6.1e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 VBB26742.1 - 0.0067 16.0 2.3 0.0067 16.0 2.3 2.3 2 0 0 2 2 2 1 GATA zinc finger Myb_DNA-bind_6 PF13921.6 VBB26742.1 - 0.065 13.5 1.6 9.4 6.6 0.2 3.7 3 1 0 3 3 3 0 Myb-like DNA-binding domain zinc_ribbon_9 PF14369.6 VBB26742.1 - 0.088 13.1 1.2 0.25 11.6 1.2 1.8 1 0 0 1 1 1 0 zinc-ribbon DUF2865 PF11064.8 VBB26742.1 - 0.13 12.7 1.6 0.21 12.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2865) UBA_4 PF14555.6 VBB26742.1 - 0.33 10.8 1.5 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain DUF1451 PF07295.11 VBB26742.1 - 0.36 10.9 2.8 0.27 11.3 0.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain IL17 PF06083.11 VBB26743.1 - 2.6e-18 66.3 2.6 4e-18 65.7 2.6 1.3 1 0 0 1 1 1 1 Interleukin-17 PP2C PF00481.21 VBB26744.1 - 1.9e-76 257.1 0.0 2.6e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 VBB26744.1 - 2.2e-23 82.5 0.1 5.1e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 VBB26744.1 - 8.7e-08 32.1 0.2 2.6e-07 30.5 0.2 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C EnY2 PF10163.9 VBB26744.1 - 0.016 15.6 0.1 0.052 13.9 0.1 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 Nucleolin_bd PF16725.5 VBB26744.1 - 0.1 12.2 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Nucleolin binding domain PAS_11 PF14598.6 VBB26745.1 - 1.9e-15 57.0 1.8 9.3e-15 54.7 0.4 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 VBB26745.1 - 8.7e-14 51.6 0.4 6.8e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 VBB26745.1 - 7.3e-06 26.0 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 VBB26745.1 - 0.0013 19.0 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain GTP_EFTU PF00009.27 VBB26746.1 - 5.9e-34 117.3 4.7 3.7e-32 111.4 4.7 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 VBB26746.1 - 6.1e-25 87.4 0.4 3.9e-24 84.8 0.0 2.6 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 VBB26746.1 - 3.1e-11 43.4 0.1 9.9e-11 41.7 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 VBB26746.1 - 3.8e-08 33.1 0.1 1e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 Ras family Arf PF00025.21 VBB26746.1 - 6e-07 29.1 0.1 1.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 VBB26746.1 - 3.2e-06 26.8 2.6 5.6e-06 26.0 0.8 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 VBB26746.1 - 8.6e-06 25.3 3.3 1e-05 25.0 0.1 2.8 3 1 0 3 3 3 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 VBB26746.1 - 0.0003 20.6 0.1 0.00081 19.2 0.1 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 VBB26746.1 - 0.00033 20.9 0.1 0.00097 19.4 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 VBB26746.1 - 0.0017 18.3 1.0 0.16 11.9 0.4 2.7 1 1 1 2 2 2 1 RsgA GTPase IF2_N PF04760.15 VBB26746.1 - 0.0037 17.1 0.2 0.023 14.5 0.1 2.4 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Dynamin_N PF00350.23 VBB26746.1 - 0.0056 16.8 0.2 2.5 8.1 0.0 3.0 2 1 1 3 3 3 1 Dynamin family TDA11 PF17084.5 VBB26746.1 - 0.068 12.1 0.9 4.6 6.1 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase I damage affected protein 11 AAA_29 PF13555.6 VBB26746.1 - 0.16 11.7 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 VBB26746.1 - 0.3 11.6 2.2 2.8 8.4 0.0 3.0 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 VBB26746.1 - 0.73 9.4 4.4 2.8 7.5 0.4 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain 7TM_GPCR_Srw PF10324.9 VBB26749.1 - 2.4e-14 53.3 29.0 2.1e-09 37.1 17.2 2.7 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 VBB26749.1 - 5.2e-13 48.9 10.4 5.2e-13 48.9 10.4 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB26749.1 - 0.00015 21.5 8.7 0.00015 21.5 8.7 3.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx TMEM156 PF15106.6 VBB26749.1 - 0.0063 16.0 0.7 0.012 15.1 0.7 1.4 1 0 0 1 1 1 1 TMEM156 protein family VMA21 PF09446.10 VBB26749.1 - 0.61 10.2 7.4 0.18 11.9 0.5 2.9 3 0 0 3 3 3 0 VMA21-like domain zf-C2H2_jaz PF12171.8 VBB26750.1 - 0.047 14.0 10.1 3.8 7.9 5.9 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 VBB26750.1 - 0.049 14.1 15.1 0.08 13.4 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26750.1 - 0.18 12.7 12.5 0.97 10.5 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Fer4_21 PF14697.6 VBB26750.1 - 0.58 10.3 4.0 7.4 6.8 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-met PF12874.7 VBB26750.1 - 5 7.6 11.1 36 4.9 7.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Nop52 PF05997.12 VBB26751.1 - 3.6e-53 180.5 8.5 7.5e-53 179.5 8.5 1.7 1 1 0 1 1 1 1 Nucleolar protein,Nop52 DUF4179 PF13786.6 VBB26751.1 - 0.023 15.2 0.1 0.14 12.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) MFS_1 PF07690.16 VBB26752.1 - 1.3e-28 99.9 41.5 2.6e-28 99.0 24.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB26752.1 - 2.1e-08 33.5 13.0 2.1e-08 33.5 13.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 VBB26752.1 - 0.00086 17.7 25.8 0.11 10.8 1.8 4.2 1 1 3 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family DUF1759 PF03564.15 VBB26753.1 - 6.3e-09 35.9 0.2 8.4e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) CAP_assoc_N PF14504.6 VBB26753.1 - 0.04 13.7 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 CAP-associated N-terminal TPR_11 PF13414.6 VBB26755.1 - 1.2e-15 56.8 3.4 0.0026 17.4 0.0 5.9 5 0 0 5 5 5 3 TPR repeat TPR_14 PF13428.6 VBB26755.1 - 5.4e-13 48.6 9.8 0.00021 21.9 0.1 7.5 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB26755.1 - 1.3e-12 46.8 30.4 5.3e-06 26.1 1.8 8.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB26755.1 - 1.3e-10 40.6 28.4 3.8e-05 23.6 0.4 9.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB26755.1 - 1.1e-09 38.4 26.7 7e-06 26.2 0.3 7.0 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB26755.1 - 1.9e-09 36.9 20.6 0.0072 16.1 1.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB26755.1 - 4.4e-09 36.8 18.8 0.024 15.3 0.7 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 VBB26755.1 - 3.4e-08 33.9 13.4 0.00072 20.0 0.1 7.1 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 VBB26755.1 - 4.3e-06 27.0 7.4 2 8.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB26755.1 - 1.2e-05 25.4 14.1 0.23 11.9 0.0 7.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 VBB26755.1 - 1.8e-05 24.1 1.8 0.3 10.3 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB26755.1 - 0.00047 20.3 13.1 0.0019 18.4 0.9 5.1 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 VBB26755.1 - 0.0028 17.1 0.1 1.3 8.3 0.0 3.0 2 1 0 2 2 2 1 Coatomer epsilon subunit NARP1 PF12569.8 VBB26755.1 - 0.004 16.1 4.7 0.19 10.6 0.3 3.4 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 VBB26755.1 - 0.0045 17.1 15.8 0.15 12.2 0.5 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 VBB26755.1 - 0.012 16.2 14.4 17 6.3 0.2 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat HlyE PF06109.13 VBB26755.1 - 0.12 11.7 0.1 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Haemolysin E (HlyE) TPR_7 PF13176.6 VBB26755.1 - 0.91 9.7 12.5 6.4 7.1 0.1 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 VBB26755.1 - 1.1 10.1 7.1 31 5.6 0.1 5.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 VBB26756.1 - 3.4e-24 85.2 0.1 5e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 YccJ PF13993.6 VBB26756.1 - 0.061 13.7 0.9 3.5 8.0 0.0 2.6 2 1 0 2 2 2 0 YccJ-like protein RNA_pol_Rbc25 PF08292.12 VBB26757.1 - 1.5e-32 112.5 5.1 8e-31 107.0 5.1 2.3 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 VBB26757.1 - 8.7e-19 67.7 0.0 1.7e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 VBB26757.1 - 0.0022 18.3 0.0 0.0055 17.0 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain Pinin_SDK_memA PF04696.13 VBB26758.1 - 2e-25 89.3 20.3 2e-25 89.3 20.3 2.5 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.13 VBB26758.1 - 3.6e-07 30.9 0.5 3.6e-07 30.9 0.5 2.9 3 1 0 3 3 3 1 pinin/SDK conserved region Ion_trans PF00520.31 VBB26759.1 - 0.0026 17.0 0.0 0.0029 16.9 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ribosomal_L35Ae PF01247.18 VBB26760.1 - 1.5e-41 140.5 2.0 1.7e-41 140.3 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 VBB26760.1 - 0.0079 16.4 0.1 4.4 7.6 0.1 2.3 2 0 0 2 2 2 2 RimM N-terminal domain Tetraspanin PF00335.20 VBB26761.1 - 1.4e-56 191.8 4.7 1.9e-56 191.4 4.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF5362 PF17319.2 VBB26761.1 - 0.018 14.9 0.9 6.8 6.6 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5362) PIG-S PF10510.9 VBB26762.1 - 8.5e-59 199.7 6.9 1.2e-58 199.3 5.8 1.7 1 1 1 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein Reoviridae_Vp9 PF08978.10 VBB26762.1 - 0.018 14.2 0.1 0.03 13.5 0.1 1.2 1 0 0 1 1 1 0 Reoviridae VP9 IPP-2 PF04979.14 VBB26763.1 - 4e-32 111.7 0.2 6.2e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) HECT PF00632.25 VBB26764.1 - 9.7e-62 209.2 0.0 2.2e-38 132.5 0.0 2.4 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 VBB26764.1 - 5.6e-18 64.9 4.2 5.6e-18 64.9 4.2 2.2 2 0 0 2 2 2 1 Mib_herc2 Ank_5 PF13857.6 VBB26764.1 - 4.1e-11 42.9 0.0 4.5e-09 36.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB26764.1 - 2.5e-10 40.8 0.0 9.6e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Sad1_UNC PF07738.13 VBB26764.1 - 8.7e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ank_3 PF13606.6 VBB26764.1 - 2.2e-06 27.6 0.0 0.042 14.4 0.0 3.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 VBB26764.1 - 7.4e-06 26.4 0.1 0.00013 22.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB26764.1 - 2e-05 24.8 0.0 0.0014 19.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ras PF00071.22 VBB26765.1 - 3.3e-55 186.1 0.1 4e-55 185.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB26765.1 - 3.2e-33 114.5 0.1 4.8e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB26765.1 - 2.8e-15 56.2 0.0 3.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB26765.1 - 8.5e-05 22.0 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB26765.1 - 0.0073 16.4 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 VBB26765.1 - 0.0086 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 VBB26765.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 VBB26765.1 - 0.011 15.5 0.1 0.25 11.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 VBB26765.1 - 0.015 15.1 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 VBB26765.1 - 0.015 15.2 0.1 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 VBB26765.1 - 0.04 13.4 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 VBB26765.1 - 0.07 13.4 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 VBB26765.1 - 0.12 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 VBB26765.1 - 0.12 12.0 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB26765.1 - 0.15 12.5 0.1 0.17 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_3 PF01171.20 VBB26766.1 - 1.3e-18 67.4 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 VBB26766.1 - 7.9e-12 44.5 6.2 7.9e-12 44.5 6.2 2.9 3 0 0 3 3 3 1 Zinc-ribbon PAPS_reduct PF01507.19 VBB26766.1 - 0.015 15.3 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 VBB26766.1 - 0.1 11.4 0.0 0.18 10.5 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase IFRD PF05004.13 VBB26767.1 - 6.3e-05 22.2 0.2 7.3e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) PAX PF00292.18 VBB26769.1 - 7.1e-72 239.2 0.6 1.1e-71 238.6 0.6 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 VBB26769.1 - 0.00012 22.6 0.2 0.031 14.9 0.0 2.5 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 VBB26769.1 - 0.0016 18.2 0.1 0.0076 16.0 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 VBB26769.1 - 0.043 13.6 0.8 0.35 10.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_28 PF13518.6 VBB26769.1 - 0.084 13.0 0.1 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.12 VBB26769.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain DUF1737 PF08410.10 VBB26769.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) TUDOR PF00567.24 VBB26770.1 - 0.0013 18.7 0.1 0.0034 17.4 0.1 1.8 1 0 0 1 1 1 1 Tudor domain Ribosomal_L10 PF00466.20 VBB26770.1 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 DNA_pol_A_exo1 PF01612.20 VBB26772.1 - 3.8e-18 65.8 0.1 3.5e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 3'-5' exonuclease Arf PF00025.21 VBB26774.1 - 2.1e-49 167.3 0.1 4.9e-49 166.1 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB26774.1 - 4.7e-11 42.9 0.0 9.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 VBB26774.1 - 2e-09 37.1 0.0 3.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 VBB26774.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 VBB26774.1 - 1.4e-07 31.1 4.6 2.4e-06 27.0 0.3 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 VBB26774.1 - 4.5e-07 29.5 0.3 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region zf-B_box PF00643.24 VBB26774.1 - 1.8e-05 24.8 4.5 1.8e-05 24.8 4.5 4.3 4 1 0 4 4 3 2 B-box zinc finger MMR_HSR1 PF01926.23 VBB26774.1 - 1.9e-05 24.7 0.0 6.6e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-RING_5 PF14634.6 VBB26774.1 - 0.0013 18.6 6.2 0.0013 18.6 6.2 3.5 2 1 0 2 2 1 1 zinc-RING finger domain ABC_tran PF00005.27 VBB26774.1 - 0.0039 17.7 0.3 0.079 13.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter zf-RING_UBOX PF13445.6 VBB26774.1 - 0.0083 16.1 7.4 0.025 14.6 7.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger AAA_14 PF13173.6 VBB26774.1 - 0.093 12.8 0.1 0.26 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF883 PF05957.13 VBB26774.1 - 0.1 13.2 6.7 4.7 7.9 0.0 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2483 PF10656.9 VBB26774.1 - 0.13 12.5 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 1 0 Hypothetical protein of unknown function (DUF2483) Nbl1_Borealin_N PF10444.9 VBB26774.1 - 0.59 9.8 5.6 1.8 8.3 1.2 2.9 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal AAA_23 PF13476.6 VBB26774.1 - 0.9 10.0 4.5 9.5 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mitofilin PF09731.9 VBB26774.1 - 2.8 6.7 11.8 4.5 6.0 11.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UPF0242 PF06785.11 VBB26774.1 - 7.7 6.6 11.3 0.33 11.0 4.9 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ank_4 PF13637.6 VBB26775.1 - 1.1e-11 44.9 0.1 2.9e-06 27.7 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) G-patch PF01585.23 VBB26775.1 - 1.8e-10 40.5 0.1 4.1e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 G-patch domain Ank_2 PF12796.7 VBB26775.1 - 9e-09 35.8 0.0 1.8e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB26775.1 - 1.1e-07 31.9 0.0 2.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB26775.1 - 2.2e-06 27.6 0.1 8.4e-05 22.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 VBB26775.1 - 3.2e-05 24.2 0.0 7.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat G-patch_2 PF12656.7 VBB26775.1 - 0.023 14.8 0.2 0.06 13.4 0.2 1.6 1 0 0 1 1 1 0 G-patch domain zf-RING_13 PF17977.1 VBB26775.1 - 4.6 7.5 6.5 7.9 6.7 0.0 3.2 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DHR-2 PF06920.13 VBB26776.1 - 6.4e-194 645.5 2.4 1.6e-193 644.1 2.4 1.7 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 VBB26776.1 - 1.4e-46 158.8 0.0 3e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 VBB26776.1 - 2.7e-18 66.4 0.1 1.3e-17 64.2 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PIN_8 PF18476.1 VBB26776.1 - 0.2 11.5 2.2 2.1 8.2 0.7 2.5 1 1 1 2 2 2 0 PIN like domain Pkinase_Tyr PF07714.17 VBB26777.1 - 3.9e-40 137.8 0.1 7.7e-40 136.8 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB26777.1 - 3.9e-25 88.7 0.2 3.9e-25 88.7 0.2 1.8 3 0 0 3 3 3 1 Protein kinase domain Kdo PF06293.14 VBB26777.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SF3b1 PF08920.10 VBB26780.1 - 4.4e-29 101.4 36.7 2.9e-25 89.1 13.5 5.5 2 2 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 VBB26780.1 - 5.5e-09 36.3 2.7 0.33 11.5 0.0 6.9 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 VBB26780.1 - 8.9e-08 31.8 13.9 1.2 9.6 0.1 8.7 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 VBB26780.1 - 9e-07 29.2 5.5 1.3 9.4 0.0 6.9 6 2 2 8 8 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 VBB26780.1 - 0.00033 21.2 2.0 4 8.1 0.0 5.2 4 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 VBB26780.1 - 0.00057 20.0 8.8 2.3 8.2 0.0 5.6 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 VBB26780.1 - 0.0034 16.0 0.2 0.2 10.2 0.2 3.0 1 1 0 1 1 1 1 Adaptin N terminal region UNC45-central PF11701.8 VBB26780.1 - 0.0057 16.6 0.1 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 VBB26780.1 - 0.0082 15.7 0.1 9.7 5.7 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal MMS19_C PF12460.8 VBB26780.1 - 0.0087 15.2 0.0 24 3.9 0.0 4.1 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TIP120 PF08623.10 VBB26780.1 - 0.069 12.9 1.4 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DUF3730 PF12530.8 VBB26780.1 - 0.17 11.4 0.2 0.56 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Arm PF00514.23 VBB26780.1 - 0.22 11.6 0.4 45 4.3 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat IML1 PF12257.8 VBB26781.1 - 3.4e-87 292.2 6.4 8.2e-86 287.7 6.4 2.3 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 VBB26781.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP_bind_1 PF03029.17 VBB26782.1 - 5e-88 294.9 0.1 5.7e-88 294.8 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 VBB26782.1 - 9.5e-05 22.3 0.0 0.00046 20.0 0.0 2.1 1 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 VBB26782.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB26782.1 - 0.0022 18.5 0.0 0.0075 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 VBB26782.1 - 0.0097 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 VBB26782.1 - 0.018 14.4 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 VBB26782.1 - 0.039 13.9 0.0 0.98 9.3 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 VBB26782.1 - 0.066 13.6 0.0 0.3 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 VBB26782.1 - 0.069 12.9 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 VBB26782.1 - 0.11 12.8 0.5 0.53 10.5 0.1 2.3 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 VBB26782.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 VBB26782.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 VBB26782.1 - 0.13 12.7 0.5 0.43 11.0 0.1 2.0 2 1 1 3 3 3 0 AAA domain SRP54 PF00448.22 VBB26782.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 VBB26782.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 VBB26782.1 - 0.24 10.4 0.0 0.57 9.1 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB F-box-like PF12937.7 VBB26784.1 - 0.0074 16.2 2.4 0.69 9.9 0.2 2.7 3 0 0 3 3 3 2 F-box-like ADD_ATRX PF17981.1 VBB26784.1 - 0.08 12.8 1.9 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 Cysteine Rich ADD domain AbiJ_NTD5 PF18865.1 VBB26785.1 - 0.017 14.9 0.6 0.053 13.3 0.6 2.0 1 1 0 1 1 1 0 AbiJ N-terminal domain 5 PTPA PF03095.15 VBB26786.1 - 1.7e-111 372.5 0.1 2e-111 372.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-C2H2 PF00096.26 VBB26787.1 - 6.7e-14 51.5 29.6 0.00045 20.5 0.5 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB26787.1 - 2.4e-13 49.7 29.6 0.0035 18.0 3.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB26787.1 - 4.5e-09 36.3 35.0 0.0033 17.8 3.3 7.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-met PF12874.7 VBB26787.1 - 5.3e-07 29.8 22.1 0.0019 18.5 0.1 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 VBB26787.1 - 5.3e-06 26.6 22.7 0.0015 18.8 5.0 3.8 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 VBB26787.1 - 5.8e-06 26.2 29.1 0.01 15.8 0.4 6.0 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB26787.1 - 0.00076 19.7 20.8 0.051 13.9 0.0 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 VBB26787.1 - 0.026 14.8 19.8 1 9.7 0.9 4.7 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 VBB26787.1 - 0.039 14.3 9.6 0.11 12.8 1.2 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon GAGA PF09237.11 VBB26787.1 - 0.44 10.4 8.8 0.9 9.4 0.0 3.9 2 2 3 5 5 5 0 GAGA factor zf-H2C2_5 PF13909.6 VBB26787.1 - 1.7 8.5 6.9 5.5 6.8 3.9 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain CpXC PF14353.6 VBB26787.1 - 3 7.9 10.1 15 5.7 0.8 3.3 2 1 1 3 3 3 0 CpXC protein zf_ZIC PF18366.1 VBB26787.1 - 5.1 7.3 6.8 7.5 6.7 0.7 3.5 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 VBB26787.1 - 7.6 7.1 16.0 0.33 11.4 1.2 3.7 3 2 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RRPl_C4 PF17026.5 VBB26787.1 - 8.6 6.5 7.9 0.35 11.0 0.2 2.4 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-MYST PF17772.1 VBB26787.1 - 9.4 5.9 9.3 0.52 10.0 0.1 3.3 4 0 0 4 4 4 0 MYST family zinc finger domain DZR PF12773.7 VBB26787.1 - 9.6 6.3 11.7 0.88 9.7 3.2 2.9 2 2 0 2 2 2 0 Double zinc ribbon SPC25 PF06703.11 VBB26790.1 - 5.6e-41 140.0 0.1 9.6e-41 139.3 0.1 1.4 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) TAF6_C PF07571.13 VBB26790.1 - 1.2e-23 83.3 0.1 2.7e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 VBB26790.1 - 2.2e-12 46.9 0.1 6.3e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF2897 PF11446.8 VBB26791.1 - 0.0037 17.1 0.2 0.0073 16.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2897) DUF1206 PF06724.11 VBB26791.1 - 0.056 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Flp_Fap PF04964.14 VBB26791.1 - 0.23 11.3 1.3 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Flp/Fap pilin component ACBP PF00887.19 VBB26792.1 - 4e-29 100.7 3.2 5.4e-29 100.2 3.2 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Tai4 PF16695.5 VBB26792.1 - 0.0027 18.2 0.1 3 8.4 0.1 2.2 2 0 0 2 2 2 2 Type VI secretion system (T6SS), amidase immunity protein NblA PF04485.12 VBB26792.1 - 0.11 13.0 0.7 0.11 13.0 0.7 2.1 2 1 0 2 2 2 0 Phycobilisome degradation protein nblA FERM_M PF00373.18 VBB26792.1 - 0.29 11.5 2.2 0.85 10.0 0.4 2.5 1 1 2 3 3 3 0 FERM central domain JTB PF05439.12 VBB26793.1 - 6.4e-23 80.9 2.5 9.8e-23 80.3 2.5 1.3 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) AMP-binding PF00501.28 VBB26794.1 - 2e-84 283.6 0.0 4e-84 282.7 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB26794.1 - 8.7e-13 49.1 0.0 1.7e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C4 PF00105.18 VBB26795.1 - 4.3e-29 100.8 20.5 7.3e-29 100.0 20.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB26795.1 - 0.00035 20.2 0.6 0.0018 17.9 0.6 2.0 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor AAA PF00004.29 VBB26796.1 - 1.1e-14 55.0 0.1 2.7e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB26796.1 - 7.1e-09 36.1 0.1 2.7e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB26796.1 - 6.5e-07 29.9 0.1 1e-05 26.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 VBB26796.1 - 1.6e-06 28.1 1.0 4.1e-06 26.8 0.2 2.1 2 0 0 2 2 1 1 AAA lid domain NB-ARC PF00931.22 VBB26796.1 - 4.9e-05 22.6 0.1 0.00012 21.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 VBB26796.1 - 9.1e-05 21.8 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 VBB26796.1 - 9.9e-05 22.7 0.1 0.00037 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 VBB26796.1 - 0.00049 20.0 0.0 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain ResIII PF04851.15 VBB26796.1 - 0.0062 16.6 0.7 0.031 14.3 0.7 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 VBB26796.1 - 0.018 15.0 1.1 0.018 15.0 1.1 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 VBB26796.1 - 0.022 14.0 1.1 0.15 11.3 0.9 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_assoc_2 PF16193.5 VBB26796.1 - 0.036 14.4 0.6 0.091 13.1 0.6 1.6 1 0 0 1 1 1 0 AAA C-terminal domain AAA_11 PF13086.6 VBB26796.1 - 0.037 13.8 0.2 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 VBB26796.1 - 0.037 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KdpD PF02702.17 VBB26796.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_32 PF13654.6 VBB26796.1 - 0.065 12.0 2.0 1 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 VBB26796.1 - 0.084 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 VBB26796.1 - 0.095 13.3 0.0 2.1 8.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 VBB26796.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 VBB26796.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 VBB26796.1 - 0.12 11.5 0.2 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain Y_phosphatase PF00102.27 VBB26797.1 - 2.4e-65 220.4 0.0 2.9e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB26797.1 - 0.00098 19.2 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 VBB26797.1 - 0.0019 18.0 0.6 0.0063 16.3 0.6 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 VBB26797.1 - 0.045 13.3 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB26797.1 - 0.096 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Bac_DnaA PF00308.18 VBB26797.1 - 0.12 12.2 0.0 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein GrpE PF01025.19 VBB26798.1 - 0.03 14.0 1.5 0.13 11.9 1.5 1.8 1 1 0 1 1 1 0 GrpE zf-RING_9 PF13901.6 VBB26798.1 - 0.04 13.9 0.2 0.071 13.1 0.2 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF4411 PF14367.6 VBB26798.1 - 0.046 13.6 1.1 0.27 11.1 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4411) PA28_beta PF02252.18 VBB26800.1 - 6.9e-60 200.9 0.2 9.9e-60 200.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 VBB26800.1 - 1.8e-14 53.5 0.5 4.1e-14 52.3 0.5 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Peptidase_C13 PF01650.18 VBB26802.1 - 3.2e-43 148.1 0.2 5.5e-43 147.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family LSM PF01423.22 VBB26802.1 - 2e-09 37.0 1.3 2.9e-08 33.3 0.2 2.3 2 0 0 2 2 2 1 LSM domain ArgoMid PF16487.5 VBB26802.1 - 0.0022 18.2 0.0 0.0074 16.5 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Hfq PF17209.3 VBB26802.1 - 0.05 13.3 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Hfq protein TMIE PF16038.5 VBB26803.1 - 6.2e-23 80.4 0.4 7.7e-23 80.1 0.4 1.2 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 VBB26803.1 - 0.0069 16.7 0.1 0.0073 16.6 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM190 PF15431.6 VBB26803.1 - 0.056 13.6 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 LapA_dom PF06305.11 VBB26803.1 - 0.081 12.7 1.1 0.13 12.0 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM100 PF16311.5 VBB26803.1 - 0.73 9.4 4.6 0.55 9.8 1.8 1.9 1 1 1 2 2 2 0 Transmembrane protein 100 EphA2_TM PF14575.6 VBB26803.1 - 0.79 10.6 3.1 1.6 9.7 3.2 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 VBB26803.1 - 2.6 8.1 5.0 6.3 6.8 4.1 1.9 1 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein HECT PF00632.25 VBB26804.1 - 4.4e-89 299.0 0.1 7.5e-89 298.2 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 VBB26804.1 - 0.0019 17.8 0.3 0.15 12.0 0.1 3.4 3 0 0 3 3 3 1 IQ calmodulin-binding motif ARID PF01388.21 VBB26804.1 - 0.017 15.7 0.2 0.98 10.1 0.0 3.1 3 0 0 3 3 3 0 ARID/BRIGHT DNA binding domain RhoGEF PF00621.20 VBB26806.1 - 4.9e-44 150.7 0.1 7.3e-44 150.2 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 VBB26806.1 - 3.9e-09 36.0 0.0 8.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 VBB26806.1 - 6e-06 26.0 0.1 1.2e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB26806.1 - 2.2e-05 24.0 0.1 4.1e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 VBB26806.1 - 0.00039 20.9 0.4 0.00085 19.8 0.4 1.5 1 0 0 1 1 1 1 PH domain PH_5 PF15405.6 VBB26806.1 - 0.052 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain ABC_tran PF00005.27 VBB26807.1 - 1.8e-50 171.0 3.4 4.1e-27 95.4 0.0 3.6 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 VBB26807.1 - 2.8e-19 70.1 1.0 2.7e-05 24.1 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 VBB26807.1 - 5.9e-11 42.2 2.5 0.0019 17.7 0.0 4.4 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 VBB26807.1 - 3.5e-08 33.5 0.9 0.00024 21.1 0.0 3.1 2 1 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 VBB26807.1 - 9.2e-08 32.6 0.0 0.0066 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 VBB26807.1 - 3.2e-07 31.0 2.3 0.005 17.4 0.0 4.0 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.6 VBB26807.1 - 8.7e-07 28.6 0.2 0.0086 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 VBB26807.1 - 1.1e-06 29.0 0.3 0.021 15.1 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 VBB26807.1 - 1.6e-06 28.5 0.0 0.059 13.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain ABC_tran_Xtn PF12848.7 VBB26807.1 - 1.7e-06 27.9 9.8 1.7e-06 27.9 9.8 2.5 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.12 VBB26807.1 - 2.2e-06 27.7 0.1 0.065 13.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 VBB26807.1 - 2.8e-06 27.8 0.1 0.12 12.8 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 VBB26807.1 - 6.7e-06 26.0 0.2 0.16 11.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 VBB26807.1 - 7.3e-06 26.0 0.0 0.15 12.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 VBB26807.1 - 2.7e-05 24.2 0.4 0.01 15.9 0.1 3.2 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 VBB26807.1 - 3.5e-05 24.0 0.2 0.48 10.6 0.0 3.3 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 VBB26807.1 - 6e-05 23.4 0.0 0.16 12.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 VBB26807.1 - 6.4e-05 22.8 4.5 0.012 15.3 0.0 3.5 4 1 0 4 4 2 2 AAA domain AAA_5 PF07728.14 VBB26807.1 - 0.00011 22.2 0.1 0.77 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 VBB26807.1 - 0.00022 21.2 8.3 0.091 12.7 0.0 3.6 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 VBB26807.1 - 0.00036 20.2 0.0 1 8.9 0.0 2.8 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 VBB26807.1 - 0.00036 21.1 0.3 0.04 14.4 0.0 4.9 4 1 1 5 5 3 2 AAA domain cobW PF02492.19 VBB26807.1 - 0.00041 20.0 0.0 0.12 12.0 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 VBB26807.1 - 0.00049 20.3 0.1 1.6 9.0 0.0 3.5 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 VBB26807.1 - 0.00056 19.9 2.8 0.35 10.8 0.0 3.3 3 1 0 3 3 3 2 NTPase NB-ARC PF00931.22 VBB26807.1 - 0.00061 19.0 0.9 0.97 8.6 0.0 2.9 3 0 0 3 3 2 2 NB-ARC domain AAA_7 PF12775.7 VBB26807.1 - 0.00086 18.9 0.0 2.1 7.8 0.0 2.9 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 VBB26807.1 - 0.0017 18.2 20.5 0.0095 15.7 0.0 4.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 VBB26807.1 - 0.0049 16.5 0.0 2.2 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 VBB26807.1 - 0.015 15.5 0.1 1.3 9.3 0.1 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 VBB26807.1 - 0.016 14.9 0.2 5.1 6.8 0.0 3.8 3 1 1 4 4 4 0 IstB-like ATP binding protein TsaE PF02367.17 VBB26807.1 - 0.017 15.1 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 VBB26807.1 - 0.017 14.8 0.3 3.6 7.3 0.0 2.7 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF87 PF01935.17 VBB26807.1 - 0.018 15.1 9.2 2.9 7.9 0.0 4.2 5 0 0 5 5 3 0 Helicase HerA, central domain AAA_27 PF13514.6 VBB26807.1 - 0.02 14.5 1.0 4.6 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 VBB26807.1 - 0.022 14.7 0.1 1.6 8.6 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 VBB26807.1 - 0.051 13.3 0.0 13 5.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 VBB26807.1 - 0.065 13.6 1.8 2.1 8.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 VBB26807.1 - 0.072 12.8 1.3 0.9 9.2 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase LTXXQ PF07813.12 VBB26807.1 - 0.18 12.5 6.3 0.71 10.6 6.3 2.0 1 0 0 1 1 1 0 LTXXQ motif family protein Dynamin_N PF00350.23 VBB26807.1 - 0.2 11.7 5.2 10 6.1 0.0 3.7 4 0 0 4 4 3 0 Dynamin family SRPRB PF09439.10 VBB26807.1 - 0.22 10.9 4.2 31 3.9 2.5 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit MCU PF04678.13 VBB26807.1 - 1.4 9.0 4.9 6.7 6.8 0.0 2.7 3 0 0 3 3 2 0 Mitochondrial calcium uniporter DUF3584 PF12128.8 VBB26807.1 - 3.4 5.0 13.2 2.3 5.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) AAA_17 PF13207.6 VBB26807.1 - 5.9 7.3 0.0 5.9 7.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain PdaC PF13739.6 VBB26807.1 - 8 7.5 8.7 7.5 7.6 4.7 2.5 2 0 0 2 2 2 0 Deacetylase PdaC Utp21 PF04192.12 VBB26808.1 - 5.4e-48 163.5 1.4 7.8e-48 163.0 1.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 VBB26808.1 - 7.2e-22 77.5 0.2 1.3e-05 25.4 0.0 7.3 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB26808.1 - 5.6e-21 74.5 1.7 0.0018 19.1 0.1 8.5 8 0 0 8 8 8 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 VBB26808.1 - 1.1e-05 25.4 0.2 0.2 11.7 0.0 3.9 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 VBB26808.1 - 0.0035 16.7 1.9 0.54 9.5 0.0 3.2 3 1 0 3 3 3 1 WD40-like domain eIF2A PF08662.11 VBB26808.1 - 0.026 14.4 0.1 2.7 7.8 0.0 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 VBB26808.1 - 0.026 14.4 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 VBB26808.1 - 0.029 14.3 0.0 30 4.8 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat Coatomer_WDAD PF04053.14 VBB26808.1 - 0.053 12.6 0.0 3.1 6.7 0.0 2.6 2 1 0 2 2 2 0 Coatomer WD associated region PQQ_2 PF13360.6 VBB26808.1 - 0.092 12.3 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 PQQ-like domain PSI PF01437.25 VBB26810.1 - 0.0016 18.9 6.4 0.0016 18.9 6.4 2.1 2 1 0 2 2 2 1 Plexin repeat Paramecium_SA PF01508.16 VBB26810.1 - 0.029 14.8 1.7 0.029 14.8 1.7 1.9 2 0 0 2 2 2 0 Paramecium surface antigen domain Nodulin_late PF07127.11 VBB26810.1 - 0.13 12.6 3.1 0.18 12.1 0.7 2.3 2 0 0 2 2 2 0 Late nodulin protein DENN PF02141.21 VBB26812.1 - 5.7e-46 156.8 0.3 9.7e-46 156.1 0.3 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 VBB26812.1 - 7.1e-10 39.5 0.5 1.4e-09 38.6 0.5 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 VBB26812.1 - 2.7e-06 27.3 0.0 1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 VBB26812.1 - 0.00099 19.0 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Pkinase PF00069.25 VBB26813.1 - 6.7e-23 81.4 0.0 1e-22 80.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26813.1 - 3.9e-15 55.8 0.0 5e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB26813.1 - 3.5e-08 32.7 0.0 5.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB26813.1 - 0.00013 21.9 0.0 0.00077 19.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family DNA_pol3_theta PF06440.11 VBB26814.1 - 0.15 11.7 0.4 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III, theta subunit SapB_2 PF03489.17 VBB26815.1 - 2.6e-10 40.2 5.3 0.00063 19.8 0.5 4.5 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.15 VBB26815.1 - 1.1e-06 28.5 23.5 0.004 17.1 0.8 6.2 7 0 0 7 7 7 3 Saposin-like type B, region 1 PA28_alpha PF02251.18 VBB26815.1 - 0.0013 18.7 0.4 0.42 10.7 0.1 3.0 2 0 0 2 2 2 2 Proteasome activator pa28 alpha subunit IL3 PF02059.15 VBB26815.1 - 0.064 13.3 3.1 0.13 12.3 0.1 2.6 2 1 0 2 2 2 0 Interleukin-3 ALMT PF11744.8 VBB26815.1 - 0.095 11.5 1.9 1 8.1 0.2 2.2 1 1 0 2 2 2 0 Aluminium activated malate transporter Synapsin_C PF02750.14 VBB26816.1 - 1.2e-35 122.9 0.4 1.6e-30 106.2 0.2 2.2 1 1 1 2 2 2 2 Synapsin, ATP binding domain Synapsin PF02078.16 VBB26816.1 - 4.6e-21 75.0 0.0 1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain APOC4 PF15119.6 VBB26816.1 - 0.075 13.3 0.0 0.75 10.1 0.0 2.5 2 1 0 2 2 2 0 Apolipoprotein C4 Ank_5 PF13857.6 VBB26817.1 - 4.9e-07 29.9 0.2 0.0024 18.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB26817.1 - 2.2e-06 28.2 0.1 1.4e-05 25.6 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB26817.1 - 0.00017 22.1 0.2 0.0008 19.9 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB26817.1 - 0.0011 19.3 0.6 0.03 14.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Cauli_VI PF01693.16 VBB26817.1 - 0.0042 17.3 0.2 0.0042 17.3 0.2 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin Ank_3 PF13606.6 VBB26817.1 - 0.0061 17.0 0.3 0.28 11.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat SIKE PF05769.11 VBB26819.1 - 1e-44 152.6 12.9 1.3e-44 152.3 12.9 1.1 1 0 0 1 1 1 1 SIKE family TolA_bind_tri PF16331.5 VBB26819.1 - 0.0011 19.0 2.7 0.0011 19.0 2.7 2.3 2 0 0 2 2 2 1 TolA binding protein trimerisation DUF5094 PF17015.5 VBB26819.1 - 0.0011 19.1 6.4 0.33 11.0 0.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5094) PMEI PF04043.15 VBB26819.1 - 0.13 12.6 2.4 0.2 12.0 2.3 1.6 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor OmpH PF03938.14 VBB26819.1 - 0.48 10.8 5.2 1 9.7 5.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_BLRF2 PF05812.12 VBB26819.1 - 0.49 10.5 5.4 1.4 9.1 1.0 2.6 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein DUF16 PF01519.16 VBB26819.1 - 1 9.9 5.9 13 6.3 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.15 VBB26819.1 - 1.1 9.1 4.5 0.72 9.7 2.1 2.0 2 0 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 VBB26819.1 - 2.8 8.0 8.5 17 5.5 8.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 VBB26819.1 - 2.9 7.9 10.8 1.1 9.3 6.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FBPase PF00316.20 VBB26820.1 - 5.6e-75 251.0 0.4 7.5e-75 250.6 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 VBB26820.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Gly_radical PF01228.21 VBB26820.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycine radical 7tm_1 PF00001.21 VBB26821.1 - 2.8e-27 95.7 19.0 4e-27 95.2 19.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 VBB26821.1 - 0.0024 17.7 4.6 0.0038 17.0 4.3 1.5 1 1 0 1 1 1 1 Olfactory receptor IF4E PF01652.18 VBB26822.1 - 2e-43 148.0 0.0 2.6e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mur_ligase_M PF08245.12 VBB26824.1 - 2.2e-07 31.1 0.5 1.4e-06 28.4 0.1 2.6 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 VBB26824.1 - 0.00073 19.8 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain CDC27 PF09507.10 VBB26824.1 - 0.0094 15.4 18.9 39 3.5 18.8 2.2 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 RAMP PF04901.13 VBB26824.1 - 0.06 13.4 0.1 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Receptor activity modifying family Glyco_transf_24 PF18404.1 VBB26826.1 - 1e-124 415.3 6.1 1.3e-119 398.6 2.1 2.6 2 1 1 3 3 3 2 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 VBB26826.1 - 3e-58 197.8 7.7 3.4e-53 181.2 0.1 3.6 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_15 PF18403.1 VBB26826.1 - 1.4e-52 178.8 5.3 7.2e-47 160.1 0.3 4.2 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 VBB26826.1 - 7.8e-45 153.1 0.1 1.6e-44 152.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 VBB26826.1 - 1.3e-39 134.6 0.0 5.1e-39 132.8 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 VBB26826.1 - 1.1e-31 109.5 0.5 7.4e-31 106.9 0.4 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 VBB26826.1 - 0.0003 20.4 0.3 0.0009 18.9 0.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_L23 PF00276.20 VBB26827.1 - 7.2e-10 39.1 0.7 1.8e-09 37.9 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 PPL4 PF18188.1 VBB26827.1 - 0.0022 17.9 0.1 0.0059 16.6 0.1 1.7 1 0 0 1 1 1 1 Prim-pol 4 zf-HIT PF04438.16 VBB26828.1 - 1.8e-11 43.7 9.6 2.6e-11 43.2 9.6 1.2 1 0 0 1 1 1 1 HIT zinc finger DPRP PF04244.13 VBB26828.1 - 0.0019 18.1 0.5 0.0024 17.8 0.5 1.1 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein zf-MYND PF01753.18 VBB26828.1 - 0.026 14.6 6.4 0.05 13.7 6.4 1.4 1 0 0 1 1 1 0 MYND finger SKA1 PF07160.12 VBB26829.1 - 0.00027 20.9 3.9 0.0023 17.8 4.0 2.3 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4974 PF16344.5 VBB26829.1 - 0.012 15.5 0.1 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) ABA_GPCR PF12430.8 VBB26831.1 - 7.6e-41 139.8 15.1 1.1e-40 139.4 11.6 2.0 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 VBB26831.1 - 3e-27 94.5 0.1 7.4e-27 93.2 0.1 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal CytB6-F_Fe-S PF08802.10 VBB26831.1 - 0.067 13.2 3.1 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit NPCC PF08058.11 VBB26831.1 - 1.8 8.6 8.8 0.55 10.3 0.1 2.6 2 1 0 2 2 2 0 Nuclear pore complex component Prenyltransf PF01255.19 VBB26832.1 - 1.6e-68 230.6 0.0 2.3e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.6 VBB26832.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) UCH PF00443.29 VBB26833.1 - 1.1e-48 166.0 0.1 1.3e-48 165.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB26833.1 - 6.7e-13 48.9 0.2 1.4e-11 44.6 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 VBB26833.1 - 3.8e-07 29.7 0.0 8.2e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 VBB26833.1 - 0.047 13.2 0.5 0.35 10.3 0.0 2.3 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF872 PF05915.12 VBB26834.1 - 0.12 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Tubulin PF00091.25 VBB26835.1 - 1.4e-62 211.4 0.0 2e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB26835.1 - 4.2e-27 94.8 0.0 9.7e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 VBB26835.1 - 0.00033 21.0 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain RNA_pol_L_2 PF13656.6 VBB26836.1 - 7.4e-24 83.3 0.0 9.8e-24 82.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 VBB26836.1 - 4.5e-08 32.4 0.0 6.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short PF00106.25 VBB26837.1 - 3.4e-46 157.2 1.3 4.5e-46 156.8 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB26837.1 - 2.1e-33 115.8 0.2 2.9e-33 115.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB26837.1 - 8.6e-14 51.8 1.6 1.4e-13 51.1 0.9 1.6 1 1 1 2 2 2 1 KR domain DUF4499 PF14934.6 VBB26837.1 - 5.6e-07 29.8 3.6 1.2e-06 28.8 3.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) 3Beta_HSD PF01073.19 VBB26837.1 - 0.00037 19.6 2.1 0.00061 18.9 2.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 VBB26837.1 - 0.0011 18.2 1.5 0.0016 17.7 1.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.21 VBB26837.1 - 0.012 14.9 1.2 0.022 14.1 1.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain G3P_antiterm PF04309.12 VBB26837.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator 3HCDH_N PF02737.18 VBB26837.1 - 0.12 12.3 0.3 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1754 PF08555.10 VBB26838.1 - 0.068 14.0 11.4 0.31 11.8 1.9 2.7 3 1 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Atg14 PF10186.9 VBB26839.1 - 3.7e-16 59.1 5.8 2.3e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 VBB26839.1 - 1.5e-05 24.1 3.1 1.5e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting 38 APG6 PF04111.12 VBB26839.1 - 0.00039 20.4 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 Apg6 BARA domain Clathrin PF00637.20 VBB26840.1 - 1.8e-15 57.0 2.5 3.5e-15 56.1 0.1 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 VBB26840.1 - 0.00057 20.3 1.2 0.00057 20.3 1.2 2.6 2 1 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 VBB26840.1 - 0.005 17.1 7.5 0.025 14.9 7.3 2.4 1 1 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.9 VBB26840.1 - 0.0066 16.7 0.4 0.19 12.0 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-rbx1 PF12678.7 VBB26840.1 - 0.0088 16.3 5.6 0.029 14.7 5.6 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 VBB26840.1 - 0.024 14.7 2.8 0.06 13.4 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 VBB26840.1 - 0.048 13.6 4.4 0.18 11.7 4.4 2.1 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 VBB26840.1 - 0.062 14.2 0.3 0.47 11.4 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_5 PF14634.6 VBB26840.1 - 0.33 11.0 6.8 1.1 9.3 6.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 VBB26840.1 - 0.43 10.5 5.0 1.9 8.4 5.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB26840.1 - 1.2 9.2 5.1 3.6 7.7 5.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB26840.1 - 1.6 8.6 6.7 8 6.4 6.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB26840.1 - 2.3 8.1 6.1 7.7 6.5 6.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 VBB26840.1 - 2.5 8.0 7.7 1.2 9.1 2.4 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ctr PF04145.15 VBB26841.1 - 7.7e-37 127.2 2.1 1.2e-36 126.6 2.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family CDC45 PF02724.14 VBB26842.1 - 0.002 16.6 15.2 0.0028 16.1 15.2 1.2 1 0 0 1 1 1 1 CDC45-like protein LAP1C PF05609.12 VBB26842.1 - 0.081 12.0 19.4 0.095 11.8 19.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Prot_ATP_ID_OB PF16450.5 VBB26842.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Hid1 PF12722.7 VBB26842.1 - 0.39 8.8 17.9 0.46 8.6 17.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.11 VBB26842.1 - 0.43 9.0 26.6 0.47 8.9 26.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 VBB26842.1 - 1.2 9.2 16.2 3 7.8 16.2 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 VBB26842.1 - 1.2 7.6 21.3 1.3 7.5 21.3 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 VBB26842.1 - 2.4 5.2 16.2 2.5 5.1 16.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 VBB26842.1 - 6.2 7.3 12.9 7.7 7.0 12.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3612 PF12268.8 VBB26843.1 - 0.026 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) PBC PF03792.13 VBB26846.1 - 6.8e-82 273.8 4.2 1.1e-81 273.1 4.2 1.3 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 VBB26846.1 - 4.7e-19 68.0 2.1 4.7e-19 68.0 2.1 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB26846.1 - 5.8e-16 58.1 1.2 2.6e-15 56.0 0.0 2.6 3 0 0 3 3 3 1 Homeobox KN domain YdaS_antitoxin PF15943.5 VBB26846.1 - 0.015 15.2 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Cor1 PF04803.12 VBB26846.1 - 0.029 14.6 1.0 0.029 14.6 1.0 2.9 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region NUC130_3NT PF08158.12 VBB26846.1 - 1.7 9.0 4.6 13 6.2 0.0 3.3 4 0 0 4 4 4 0 NUC130/3NT domain Phospholip_B PF04916.13 VBB26847.1 - 1e-171 572.2 2.5 1.7e-171 571.4 2.5 1.3 1 0 0 1 1 1 1 Phospholipase B ANAPC4_WD40 PF12894.7 VBB26847.1 - 0.0081 16.4 0.0 3.5 8.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M8 PF01457.16 VBB26848.1 - 3.7e-61 207.4 5.0 1e-36 126.7 0.0 2.7 1 1 1 2 2 2 2 Leishmanolysin Exo70 PF03081.15 VBB26848.1 - 0.0037 16.4 0.5 0.006 15.7 0.5 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Folliculin PF11704.8 VBB26848.1 - 0.14 12.1 0.1 0.38 10.6 0.1 1.8 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport CLPTM1 PF05602.12 VBB26850.1 - 8.9e-156 519.2 1.8 1.1e-155 518.9 1.8 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) CsiV PF10972.8 VBB26850.1 - 0.014 15.1 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV PQ-loop PF04193.14 VBB26850.1 - 0.023 14.5 7.0 0.35 10.7 1.7 2.7 2 0 0 2 2 2 0 PQ loop repeat SET PF00856.28 VBB26851.1 - 5.3e-17 62.7 1.1 1.5e-16 61.3 0.4 2.2 2 1 0 2 2 2 1 SET domain PHD PF00628.29 VBB26851.1 - 3.6 7.5 39.2 0.029 14.3 3.1 4.3 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.6 VBB26851.1 - 5.9 6.9 20.5 3 7.9 1.7 3.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 7TM_GPCR_Srx PF10328.9 VBB26852.1 - 3.1e-12 46.7 36.7 2.3e-11 43.8 21.7 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 VBB26852.1 - 6.4e-08 31.9 31.6 1.3e-05 24.4 18.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt Phosphodiest PF01663.22 VBB26853.1 - 8.1e-44 150.6 0.1 1e-43 150.3 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SET PF00856.28 VBB26854.1 - 1.7e-10 41.5 0.0 4.1e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 SET domain COX5A PF02284.16 VBB26855.1 - 7.1e-37 125.6 0.0 1.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Reprolysin PF01421.19 VBB26856.1 - 3.3e-33 115.3 0.4 3.3e-33 115.3 0.4 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 VBB26856.1 - 9.5e-21 74.5 0.0 2.6e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.12 VBB26856.1 - 1.6e-19 70.4 8.4 1.6e-19 70.4 8.4 4.2 4 0 0 4 4 3 1 ADAM cysteine-rich Disintegrin PF00200.23 VBB26856.1 - 1.8e-16 60.7 25.3 1.8e-16 60.7 25.3 4.7 4 0 0 4 4 2 1 Disintegrin FeS_assembly_P PF01883.19 VBB26856.1 - 9.8e-11 41.7 0.1 2.7e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Reprolysin_5 PF13688.6 VBB26856.1 - 2.2e-09 37.8 0.5 8e-09 35.9 0.5 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 VBB26856.1 - 7.8e-05 23.2 0.8 0.00021 21.8 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 VBB26856.1 - 0.0002 21.1 0.4 0.00066 19.4 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 VBB26856.1 - 0.0012 19.2 9.8 0.0012 19.2 9.8 5.5 5 1 1 6 6 6 1 EGF-like domain CD34_antigen PF06365.12 VBB26856.1 - 0.0046 16.6 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family SIT PF15330.6 VBB26856.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM51 PF15345.6 VBB26856.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 FtsJ PF01728.19 VBB26857.1 - 2.6e-42 144.9 0.0 3.4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 VBB26857.1 - 0.0046 16.8 0.0 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB26857.1 - 0.017 14.9 0.0 0.021 14.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DUF5420 PF17457.2 VBB26857.1 - 0.03 14.2 3.2 0.057 13.3 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5420) DUF2119 PF09892.9 VBB26857.1 - 0.032 13.6 0.1 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) mIF3 PF14877.6 VBB26857.1 - 0.051 13.2 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Pkinase_Tyr PF07714.17 VBB26858.1 - 2.5e-46 158.1 0.0 3.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB26858.1 - 2.3e-26 92.8 0.0 3.5e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 VBB26858.1 - 0.00098 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MRP-L28 PF09812.9 VBB26859.1 - 6.2e-29 101.2 6.3 8.1e-29 100.8 6.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GPS2_interact PF15784.5 VBB26859.1 - 7.6 7.1 11.6 2.7 8.5 4.7 2.3 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Pam16 PF03656.13 VBB26860.1 - 5.3e-44 149.3 5.0 8.7e-44 148.6 5.0 1.3 1 0 0 1 1 1 1 Pam16 COMM_domain PF07258.14 VBB26860.1 - 1.2e-05 25.3 0.1 2.4e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 COMM domain DUF5528 PF17666.1 VBB26860.1 - 1.4 8.8 5.8 5 7.1 0.0 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5528) Mito_fiss_reg PF05308.11 VBB26861.1 - 0.0042 17.2 2.4 0.0042 17.2 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.19 VBB26861.1 - 0.0073 15.8 7.9 0.0083 15.7 7.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 VBB26861.1 - 0.011 15.7 10.0 0.014 15.4 10.0 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Peptidase_M16_C PF05193.21 VBB26861.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.1 1 0 0 1 1 1 0 Peptidase M16 inactive domain Metallophos PF00149.28 VBB26862.1 - 2.2e-40 139.3 0.1 3.2e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB26862.1 - 1.7e-19 70.0 2.8 2.8e-19 69.3 1.7 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain BCAS3 PF12490.8 VBB26863.1 - 5.2e-12 45.8 4.8 2.3e-05 24.1 0.1 2.6 2 1 1 3 3 3 2 Breast carcinoma amplified sequence 3 Oxysterol_BP PF01237.18 VBB26864.1 - 5.5e-46 157.1 5.5 4e-35 121.4 2.9 3.2 1 1 1 2 2 2 2 Oxysterol-binding protein ASD2 PF08687.11 VBB26865.1 - 2e-17 63.7 9.2 2e-17 63.7 9.2 1.9 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 GRAB PF10375.9 VBB26865.1 - 0.055 13.4 0.3 0.12 12.3 0.3 1.6 1 0 0 1 1 1 0 GRIP-related Arf-binding domain GvpG PF05120.12 VBB26865.1 - 0.095 12.7 1.3 0.28 11.2 0.6 2.3 1 1 0 1 1 1 0 Gas vesicle protein G SpoOE-like PF09388.10 VBB26865.1 - 1.5 8.8 6.1 7 6.6 1.1 3.6 2 1 1 3 3 3 0 Spo0E like sporulation regulatory protein GCN5L1 PF06320.13 VBB26866.1 - 1.5e-25 89.5 9.2 1.9e-25 89.2 9.2 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Peptidase_M17 PF00883.21 VBB26866.1 - 0.053 12.8 0.1 0.059 12.6 0.1 1.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain Arm-DNA-bind_5 PF17293.2 VBB26866.1 - 1.9 9.0 7.7 0.25 11.8 1.7 2.0 1 1 1 2 2 2 0 Arm DNA-binding domain PHD PF00628.29 VBB26867.1 - 6.7e-08 32.3 10.0 1.1e-07 31.6 10.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 VBB26867.1 - 0.00043 20.5 2.4 0.001 19.3 2.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 VBB26867.1 - 0.0097 16.1 1.7 0.018 15.2 1.7 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain DUF3829 PF12889.7 VBB26867.1 - 0.011 15.3 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) ING PF12998.7 VBB26867.1 - 0.014 16.0 2.4 0.017 15.7 0.4 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ParB_C PF18064.1 VBB26867.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal zf-RING-like PF08746.11 VBB26867.1 - 0.16 12.3 5.8 0.28 11.5 5.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_2 PF13639.6 VBB26867.1 - 0.45 10.9 8.7 0.75 10.2 8.7 1.3 1 0 0 1 1 1 0 Ring finger domain GAT PF03127.14 VBB26867.1 - 0.85 10.0 4.3 0.79 10.1 0.1 2.7 3 1 1 4 4 4 0 GAT domain zf-4CXXC_R1 PF10497.9 VBB26867.1 - 4.8 7.5 10.3 17 5.7 10.3 1.8 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Mago-bind PF09282.10 VBB26868.1 - 1.3e-14 53.8 0.7 3.2e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 Mago binding Homeodomain PF00046.29 VBB26869.1 - 4.8e-21 74.4 4.5 9.7e-21 73.4 4.5 1.5 1 0 0 1 1 1 1 Homeodomain PDCD2_C PF04194.13 VBB26870.1 - 2.1e-42 145.1 0.0 2.1e-42 145.1 0.0 3.2 3 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 VBB26870.1 - 2.2e-10 40.4 18.1 2.2e-10 40.4 18.1 3.3 6 0 0 6 6 6 1 MYND finger rRNA_processing PF08524.11 VBB26870.1 - 0.093 12.7 0.2 0.36 10.9 0.0 1.8 1 1 1 2 2 2 0 rRNA processing Cwf_Cwc_15 PF04889.12 VBB26870.1 - 0.097 12.4 9.3 0.14 11.9 9.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VWA_N2 PF16164.5 VBB26870.1 - 0.45 10.7 5.4 13 6.0 3.6 2.6 2 0 0 2 2 2 0 VWA N-terminal VMA21 PF09446.10 VBB26871.1 - 3.9e-09 36.5 15.2 6.9e-09 35.7 15.2 1.4 1 0 0 1 1 1 1 VMA21-like domain ORC3_N PF07034.11 VBB26871.1 - 3.1e-08 33.1 0.2 6.3e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF2207 PF09972.9 VBB26871.1 - 0.017 13.9 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cytomega_TRL10 PF06084.11 VBB26871.1 - 0.094 12.7 0.8 16 5.5 0.0 2.7 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein DUF3021 PF11457.8 VBB26871.1 - 0.84 10.0 10.5 0.078 13.3 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) RseC_MucC PF04246.12 VBB26871.1 - 0.84 9.6 5.0 1.8 8.5 5.0 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2070 PF09843.9 VBB26871.1 - 1.7 6.8 4.1 2.8 6.1 4.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-Di19 PF05605.12 VBB26872.1 - 0.0024 18.1 0.4 0.006 16.9 0.4 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF3795 PF12675.7 VBB26872.1 - 0.04 14.3 0.7 0.11 12.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-C2H2_4 PF13894.6 VBB26872.1 - 0.041 14.7 7.7 0.34 11.9 1.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 VBB26872.1 - 0.093 12.8 0.5 0.24 11.5 0.5 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type RNA_pol_I_TF PF04090.12 VBB26872.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor zf-met PF12874.7 VBB26872.1 - 0.17 12.3 0.9 0.43 11.1 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB26872.1 - 0.23 11.8 1.4 0.63 10.4 1.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.6 VBB26872.1 - 0.39 10.7 3.5 4.7 7.2 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 VBB26872.1 - 0.44 10.3 3.9 0.17 11.7 0.8 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 VBB26872.1 - 1.4 9.3 6.4 0.98 9.8 0.3 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 VBB26872.1 - 2.6 8.6 7.9 15 6.2 3.9 3.0 2 1 1 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 VBB26872.1 - 3.2 8.4 8.7 6.9 7.3 2.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L11_N PF03946.14 VBB26873.1 - 2.3e-22 78.6 1.2 3.3e-22 78.1 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 VBB26873.1 - 5.5e-18 65.2 0.2 5.5e-18 65.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Actin PF00022.19 VBB26875.1 - 4.1e-151 503.2 0.0 1.3e-150 501.6 0.0 1.6 1 1 0 1 1 1 1 Actin Helicase_C_2 PF13307.6 VBB26876.1 - 2.1e-48 164.7 0.0 5e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 VBB26876.1 - 7.2e-42 143.0 0.1 1.9e-41 141.6 0.1 1.8 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 VBB26876.1 - 0.00011 22.2 0.2 0.0075 16.3 0.1 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB26876.1 - 0.00024 20.9 0.4 0.0098 15.7 0.1 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 VBB26876.1 - 0.019 14.5 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 VBB26876.1 - 0.063 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2615 PF11027.8 VBB26877.1 - 9e-36 122.2 0.0 1.1e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) SNF2_N PF00176.23 VBB26878.1 - 1.7e-50 171.7 1.0 1.7e-50 171.7 1.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB26878.1 - 9.9e-21 74.2 0.0 1.2e-18 67.4 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB26878.1 - 2.8e-11 43.7 0.1 1.8e-10 41.1 0.1 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 VBB26878.1 - 1.2e-06 27.9 0.1 3e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 VBB26878.1 - 0.0028 17.9 0.1 0.02 15.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Pkip-1 PF06878.11 VBB26878.1 - 0.0036 17.4 1.8 0.031 14.4 0.0 3.0 3 0 0 3 3 3 1 Pkip-1 protein IstB_IS21_ATP PF08483.11 VBB26878.1 - 0.032 14.1 0.3 0.069 13.1 0.3 1.5 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal Plk4_PB2 PF18409.1 VBB26878.1 - 1.8 9.2 6.7 1.5 9.5 0.0 3.4 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 ECF_trnsprt PF12822.7 VBB26879.1 - 0.004 17.3 0.0 0.0053 16.9 0.0 1.2 1 0 0 1 1 1 1 ECF transporter, substrate-specific component Trans_coact PF16805.5 VBB26879.1 - 0.024 14.7 0.1 0.13 12.4 0.0 2.2 1 1 1 2 2 2 0 Phage late-transcription coactivator Tetraspanin PF00335.20 VBB26879.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Hum_adeno_E3A PF05393.11 VBB26879.1 - 0.043 13.8 0.4 0.091 12.8 0.4 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein LapA_dom PF06305.11 VBB26879.1 - 0.049 13.5 0.5 0.049 13.5 0.5 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 VBB26879.1 - 0.068 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 VBB26879.1 - 0.39 10.6 0.0 0.39 10.6 0.0 4.1 4 1 0 4 4 4 0 TMEM154 protein family WBP-1 PF11669.8 VBB26879.1 - 2.8 8.6 8.1 0.28 11.8 0.4 2.9 2 1 0 2 2 2 0 WW domain-binding protein 1 CUE PF02845.16 VBB26880.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 CUE domain RBFA PF02033.18 VBB26881.1 - 2e-07 31.4 0.1 3.4e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A YGGT PF02325.17 VBB26881.1 - 0.054 13.9 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 YGGT family Tubulin PF00091.25 VBB26882.1 - 2.3e-09 37.7 0.2 3.4e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF2457 PF10446.9 VBB26883.1 - 0.92 8.6 23.7 1 8.4 23.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 VBB26883.1 - 2.1 6.4 19.6 2.3 6.2 19.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 VBB26883.1 - 9.8 4.2 12.0 10 4.2 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family Lipase_2 PF01674.18 VBB26884.1 - 7.2e-75 251.3 0.0 8.6e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 2) Cpn60_TCP1 PF00118.24 VBB26885.1 - 3e-157 524.2 5.4 3.4e-157 524.0 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TraG_N PF07916.11 VBB26885.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Peptidase_S9 PF00326.21 VBB26886.1 - 8e-47 159.4 0.0 1.2e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 VBB26886.1 - 1.4e-11 44.4 0.0 2.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 VBB26886.1 - 1.1e-08 34.7 0.0 0.00086 18.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 VBB26886.1 - 1.7e-07 31.3 0.0 1.7e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 VBB26886.1 - 3.3e-06 26.2 0.0 5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.18 VBB26886.1 - 6.5e-06 25.9 0.0 0.034 13.7 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 VBB26886.1 - 3.5e-05 23.2 0.0 0.022 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 VBB26886.1 - 7.9e-05 22.6 0.0 0.0039 17.0 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 VBB26886.1 - 0.00048 19.9 0.1 0.68 9.5 0.1 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 VBB26886.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 VBB26886.1 - 0.021 13.5 0.0 0.096 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 VBB26886.1 - 0.074 13.0 0.0 2.6 7.9 0.0 2.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.12 VBB26886.1 - 0.092 12.7 0.4 0.54 10.3 0.4 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Esterase_phd PF10503.9 VBB26886.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Esterase PHB depolymerase SH3_9 PF14604.6 VBB26887.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Collagen PF01391.18 VBB26888.1 - 1.2e-24 85.8 84.6 1.9e-10 40.3 33.0 3.8 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB26888.1 - 4.4e-11 42.7 0.1 6e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Clathrin PF00637.20 VBB26889.1 - 6.1e-203 664.9 48.6 2.5e-33 115.0 2.4 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 VBB26889.1 - 5.8e-40 133.7 3.1 2.7e-06 27.4 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 VBB26889.1 - 1e-30 105.4 1.9 4.6e-30 103.3 0.0 3.2 4 0 0 4 4 4 1 Clathrin-H-link Clathrin-link PF09268.10 VBB26889.1 - 2e-12 46.3 0.1 4.6e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 VBB26889.1 - 2.1e-05 23.7 6.5 0.038 13.0 0.1 4.3 4 0 0 4 4 4 2 Coatomer WD associated region TPR_14 PF13428.6 VBB26889.1 - 0.0033 18.1 6.1 69 4.7 0.3 8.6 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 VBB26889.1 - 0.055 13.5 14.0 1.1 9.4 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Flavodoxin_1 PF00258.25 VBB26890.1 - 3.4e-06 27.3 0.0 5.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Pkinase PF00069.25 VBB26891.1 - 0.037 13.4 0.1 0.18 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.23 VBB26891.1 - 0.15 12.0 1.5 0.27 11.1 1.5 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mre11_DNA_bind PF04152.14 VBB26892.1 - 1e-19 71.5 0.7 1.8e-19 70.7 0.7 1.4 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 VBB26892.1 - 5.1e-16 59.8 0.2 1.7e-15 58.1 0.2 2.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB26892.1 - 1.9e-05 24.9 0.0 8.2e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zn_ribbon_17 PF17120.5 VBB26892.1 - 0.00027 20.5 13.9 0.0009 18.8 13.9 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 VBB26892.1 - 0.0012 19.7 18.2 0.056 14.3 0.0 7.0 6 1 1 7 7 7 2 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 VBB26892.1 - 0.25 11.6 7.1 0.74 10.0 7.1 1.9 1 0 0 1 1 1 0 Zinc-ribbon like family LUC7 PF03194.15 VBB26893.1 - 1e-68 231.7 22.1 1e-68 231.7 22.1 1.8 1 1 1 2 2 2 1 LUC7 N_terminus Cas_DxTHG PF09455.10 VBB26893.1 - 4 6.9 11.0 5.1 6.6 11.0 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Pkinase PF00069.25 VBB26894.1 - 4.3e-29 101.7 0.0 1.2e-27 97.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26894.1 - 9.7e-27 93.9 0.0 6.5e-25 87.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 VBB26894.1 - 0.00021 22.3 14.0 0.00045 21.2 14.0 1.6 1 0 0 1 1 1 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 VBB26894.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase KH_1 PF00013.29 VBB26896.1 - 1.5e-08 34.3 0.0 2.1e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 KH domain Vps53_N PF04100.12 VBB26897.1 - 2.2e-110 369.2 7.0 4.2e-110 368.3 7.0 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 VBB26897.1 - 3.2e-06 27.2 0.4 4.9e-05 23.3 0.1 2.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus MH2 PF03166.14 VBB26898.1 - 2.1e-63 213.9 0.8 3e-63 213.4 0.8 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 VBB26898.1 - 1.2e-39 134.7 2.6 2.8e-39 133.5 2.6 1.7 1 0 0 1 1 1 1 MH1 domain Nuc_sug_transp PF04142.15 VBB26899.1 - 2.2e-88 296.5 19.4 6.5e-85 285.0 14.1 2.0 1 1 1 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 VBB26899.1 - 3.4e-05 24.1 3.7 3.4e-05 24.1 3.7 3.3 2 2 1 3 3 3 2 EamA-like transporter family WD40 PF00400.32 VBB26900.1 - 8.9e-26 89.7 30.7 1e-05 26.2 0.2 8.9 8 1 0 8 8 8 5 WD domain, G-beta repeat Hira PF07569.11 VBB26900.1 - 3.6e-11 43.2 4.1 1.6e-08 34.6 0.3 3.0 2 1 1 3 3 3 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 VBB26900.1 - 1.4e-10 41.3 0.3 0.095 13.0 0.0 5.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 VBB26900.1 - 4.5e-05 23.2 0.1 9.6e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 VBB26900.1 - 0.011 15.7 1.8 13 5.8 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PAP_assoc PF03828.19 VBB26901.1 - 2.3e-23 82.1 0.2 4.1e-16 58.9 0.0 2.9 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 VBB26901.1 - 0.0039 17.5 0.0 0.097 13.0 0.0 2.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain CoiA PF06054.11 VBB26901.1 - 0.03 13.5 3.3 0.013 14.7 0.8 1.6 2 0 0 2 2 2 0 Competence protein CoiA-like family zf-CCHC_2 PF13696.6 VBB26901.1 - 0.047 13.5 17.0 0.26 11.2 6.4 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 VBB26901.1 - 0.056 13.5 15.4 0.12 12.5 3.8 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 VBB26901.1 - 8.4 6.3 10.2 1.1 9.2 0.8 2.6 2 0 0 2 2 2 0 Zinc knuckle Na_H_Exchanger PF00999.21 VBB26902.1 - 6.9e-27 94.2 31.3 6.9e-27 94.2 31.3 2.8 2 1 1 3 3 3 1 Sodium/hydrogen exchanger family PHO4 PF01384.20 VBB26902.1 - 3.5 6.6 9.6 0.59 9.1 0.4 2.8 2 1 0 2 2 2 0 Phosphate transporter family BRICHOS PF04089.14 VBB26903.1 - 0.00032 20.9 0.0 0.0012 19.0 0.0 2.0 1 0 0 1 1 1 1 BRICHOS domain zf-LITAF-like PF10601.9 VBB26903.1 - 3.8 7.8 5.1 23 5.3 0.0 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain ASC PF00858.24 VBB26904.1 - 4.5e-19 68.8 12.2 1.9e-13 50.2 0.6 3.3 2 1 0 2 2 2 2 Amiloride-sensitive sodium channel DUF2229 PF09989.9 VBB26904.1 - 0.019 14.6 0.4 0.051 13.2 0.4 1.7 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Motile_Sperm PF00635.26 VBB26905.1 - 1.2e-10 41.2 0.0 2.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TB2_DP1_HVA22 PF03134.19 VBB26905.1 - 0.0074 16.2 1.4 0.094 12.7 1.7 2.2 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DAGK_acc PF00609.19 VBB26906.1 - 6.9e-45 153.2 0.0 1.4e-44 152.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 VBB26906.1 - 6.8e-27 93.6 0.0 1.5e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 VBB26906.1 - 3.7e-08 33.1 29.2 3.1e-07 30.2 17.3 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 VBB26906.1 - 4.5 7.3 8.9 23 5.1 2.4 2.9 2 1 0 2 2 2 0 Adenylate kinase, active site lid Snf7 PF03357.21 VBB26908.1 - 6.2e-48 162.7 13.5 6.2e-48 162.7 13.5 1.4 2 0 0 2 2 2 1 Snf7 SYF2 PF08231.12 VBB26908.1 - 0.85 10.0 7.9 1.5 9.2 7.9 1.6 1 1 0 1 1 1 0 SYF2 splicing factor V_ATPase_I PF01496.19 VBB26908.1 - 1.8 6.3 7.7 2.3 6.0 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_9 PF13901.6 VBB26909.1 - 6.3e-53 179.8 9.9 6.3e-53 179.8 9.9 2.3 2 1 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 VBB26909.1 - 3.6e-21 75.6 0.0 9.7e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 RUN domain zf-C3H2C3 PF17122.5 VBB26909.1 - 1.2 9.2 7.4 3.1 7.9 7.4 1.8 1 0 0 1 1 1 0 Zinc-finger Zf_RING PF16744.5 VBB26909.1 - 4 7.6 7.6 13 5.9 7.6 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger PH PF00169.29 VBB26910.1 - 1.7e-09 38.1 0.2 3.4e-09 37.1 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 VBB26910.1 - 0.031 14.6 0.0 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Patched PF02460.18 VBB26911.1 - 2.3e-79 267.5 19.0 2.5e-79 267.3 19.0 1.0 1 0 0 1 1 1 1 Patched family SecD_SecF PF02355.16 VBB26911.1 - 0.0072 15.7 15.3 0.018 14.5 15.2 1.6 1 1 0 1 1 1 1 Protein export membrane protein ACR_tran PF00873.19 VBB26911.1 - 0.01 13.5 10.4 0.012 13.3 10.4 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Patched PF02460.18 VBB26912.1 - 1.1e-98 331.4 10.7 1.5e-98 330.9 10.7 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB26912.1 - 2.3e-28 99.0 7.2 2.3e-28 99.0 7.2 3.0 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 VBB26912.1 - 0.0042 16.1 7.5 0.016 14.1 7.6 1.7 1 1 0 1 1 1 1 MMPL family LapA_dom PF06305.11 VBB26912.1 - 2.6 7.9 5.3 29 4.6 1.1 3.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF5392 PF17370.2 VBB26913.1 - 0.045 13.9 0.9 0.075 13.1 0.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5392) Ada3 PF10198.9 VBB26914.1 - 2.2e-05 24.6 0.3 5.1e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 zf-C2H2_4 PF13894.6 VBB26915.1 - 3.7e-06 27.3 42.3 0.7 10.9 0.2 8.0 7 0 0 7 7 7 7 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 VBB26915.1 - 0.022 14.4 5.8 0.6 9.8 0.2 3.9 3 1 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain RRM_1 PF00076.22 VBB26916.1 - 2.5e-44 149.0 0.2 1.9e-15 56.4 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSCB_C PF07743.13 VBB26916.1 - 2.8e-09 37.3 1.4 1.7e-07 31.6 0.2 2.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 VBB26916.1 - 3.8e-05 23.7 3.6 0.00015 21.9 0.0 3.0 4 0 0 4 4 4 1 DnaJ domain RRM_5 PF13893.6 VBB26916.1 - 9.9e-05 21.9 0.0 0.11 12.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB26916.1 - 0.0057 16.5 0.0 0.75 9.7 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4523 PF15023.6 VBB26916.1 - 0.019 14.8 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) HscB_4_cys PF18256.1 VBB26916.1 - 0.02 14.7 3.1 0.059 13.2 3.1 1.9 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif LepA_C PF06421.12 VBB26916.1 - 0.15 12.2 1.1 0.36 11.0 1.1 1.6 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus IMS PF00817.20 VBB26917.1 - 1.9e-40 138.3 0.2 3.7e-40 137.4 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 VBB26917.1 - 8.6e-13 49.0 0.1 1.7e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 VBB26917.1 - 2.2e-06 27.7 0.1 4.8e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif amfpi-1 PF12190.8 VBB26917.1 - 0.032 14.9 0.5 0.1 13.2 0.5 1.8 1 0 0 1 1 1 0 Fungal protease inhibitor RNF220 PF15926.5 VBB26917.1 - 0.09 12.4 0.2 0.66 9.6 0.1 2.2 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 AhpC-TSA PF00578.21 VBB26918.1 - 2.6e-33 114.6 0.0 1e-22 80.4 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family 1-cysPrx_C PF10417.9 VBB26918.1 - 1.4e-09 37.6 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 VBB26918.1 - 3.4e-09 36.6 0.0 1.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Redoxin PHR PF08005.12 VBB26919.1 - 1.2e-47 162.3 0.1 2.1e-47 161.6 0.1 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 VBB26919.1 - 2.5e-19 69.5 0.0 1.5e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 VBB26919.1 - 6.1e-08 32.7 0.0 2.3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 BTB And C-terminal Kelch DUF4082 PF13313.6 VBB26919.1 - 0.045 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) MAM PF00629.23 VBB26920.1 - 8e-17 61.6 0.4 1.2e-08 35.0 0.0 3.1 4 0 0 4 4 4 2 MAM domain, meprin/A5/mu Peptidase_S8 PF00082.22 VBB26921.1 - 2.3e-45 155.2 1.7 3.3e-45 154.6 1.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 VBB26921.1 - 1.1e-23 83.0 0.1 2e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 VBB26921.1 - 3.7e-13 50.0 2.7 9.2e-13 48.8 2.7 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 VBB26922.1 - 0.0015 18.6 17.5 0.0015 18.6 17.5 2.3 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich VSP PF03302.13 VBB26922.1 - 0.017 14.0 37.7 0.24 10.2 13.2 2.4 1 1 0 2 2 2 0 Giardia variant-specific surface protein Furin-like PF00757.20 VBB26922.1 - 9.6 6.1 47.1 14 5.5 35.1 3.3 1 1 1 2 2 2 0 Furin-like cysteine rich region RRF PF01765.19 VBB26923.1 - 6.6e-16 58.7 4.5 1.3e-15 57.7 4.5 1.5 1 0 0 1 1 1 1 Ribosome recycling factor ING PF12998.7 VBB26924.1 - 0.023 15.3 0.1 0.14 12.8 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding V-ATPase_C PF03223.15 VBB26925.1 - 1.5e-58 199.0 2.4 1.8e-58 198.7 2.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Proteasome PF00227.26 VBB26926.1 - 1.6e-27 96.2 0.0 1.9e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3912 PF13051.6 VBB26926.1 - 0.051 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) Ribosomal_L34e PF01199.18 VBB26927.1 - 6.5e-38 128.9 6.3 8.5e-38 128.6 6.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e zf-met PF12874.7 VBB26928.1 - 2.2e-20 72.3 21.0 4.9e-07 29.9 1.8 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB26928.1 - 1.1e-15 57.4 21.4 8.5e-06 25.9 2.9 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding DZF PF07528.14 VBB26928.1 - 3.3e-05 23.6 0.2 0.0001 22.1 0.2 1.8 1 0 0 1 1 1 1 DZF domain zf-C2H2_2 PF12756.7 VBB26928.1 - 0.0081 16.5 20.5 0.5 10.7 3.6 3.9 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) LAL_C2 PF18603.1 VBB26928.1 - 0.036 14.2 1.0 0.036 14.2 1.0 2.6 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 zf-C2H2_4 PF13894.6 VBB26928.1 - 0.094 13.6 11.5 3.8 8.6 0.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB26928.1 - 0.16 12.5 18.5 2.6 8.7 1.8 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3449 PF11931.8 VBB26928.1 - 0.2 11.4 0.1 0.2 11.4 0.1 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3449) zf-DBF PF07535.12 VBB26928.1 - 0.27 11.4 17.4 2.7 8.2 3.0 3.6 3 0 0 3 3 3 0 DBF zinc finger zf-U1 PF06220.12 VBB26928.1 - 0.45 10.3 17.4 1.9 8.3 2.0 3.6 3 0 0 3 3 3 0 U1 zinc finger GcrA PF07750.11 VBB26928.1 - 4.8 7.6 9.4 0.18 12.2 0.2 2.8 2 1 0 2 2 2 0 GcrA cell cycle regulator MOLO1 PF17175.4 VBB26929.1 - 4.1e-17 62.4 0.2 1.2e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 VBB26929.1 - 0.00057 20.0 0.7 0.033 14.4 0.1 2.9 3 0 0 3 3 3 1 TPM domain Aldo_ket_red PF00248.21 VBB26930.1 - 1.2e-43 149.4 0.1 4.6e-42 144.2 0.1 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family FAM184 PF15665.5 VBB26931.1 - 0.0021 17.9 21.2 0.0021 17.9 21.2 4.1 2 2 1 4 4 4 1 Family with sequence similarity 184, A and B THP2 PF09432.10 VBB26931.1 - 0.046 13.8 0.7 0.046 13.8 0.7 3.8 2 1 1 4 4 4 0 Tho complex subunit THP2 DUF3479 PF11965.8 VBB26931.1 - 0.064 13.4 3.1 0.061 13.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) TrbI_Ftype PF09677.10 VBB26931.1 - 0.069 13.5 1.8 0.19 12.1 0.4 2.4 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Hormone_1 PF00103.20 VBB26931.1 - 0.32 10.7 18.3 6.4 6.5 1.5 4.3 3 1 0 4 4 4 0 Somatotropin hormone family ApoO PF09769.9 VBB26931.1 - 0.5 10.3 3.4 1.8 8.5 0.3 2.7 2 0 0 2 2 2 0 Apolipoprotein O UPF0242 PF06785.11 VBB26931.1 - 0.73 9.9 58.4 0.15 12.2 14.2 5.1 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus BORCS8 PF10167.9 VBB26931.1 - 0.88 9.5 11.5 2.2 8.3 0.4 4.1 3 1 1 4 4 4 0 BLOC-1-related complex sub-unit 8 SLED PF12140.8 VBB26931.1 - 0.92 10.0 4.2 0.38 11.3 0.2 2.4 3 0 0 3 3 3 0 SLED domain Coat_F PF07875.12 VBB26931.1 - 3.2 8.1 5.9 0.99 9.7 1.5 2.5 2 0 0 2 2 2 0 Coat F domain DUF948 PF06103.11 VBB26931.1 - 5.5 7.3 18.6 2.8 8.3 1.0 4.4 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2367 PF10164.9 VBB26932.1 - 6.2e-05 23.5 7.6 6.2e-05 23.5 7.6 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) zf-C2H2_9 PF16293.5 VBB26932.1 - 0.018 14.9 0.5 1 9.3 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-piccolo PF05715.13 VBB26932.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.1 2 2 1 3 3 3 0 Piccolo Zn-finger zf-Di19 PF05605.12 VBB26932.1 - 0.42 10.9 5.3 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MHC_II_beta PF00969.19 VBB26933.1 - 0.25 11.5 2.2 12 6.1 0.2 3.8 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain JmjC PF02373.22 VBB26935.1 - 6.6e-41 139.3 0.8 1.4e-40 138.3 0.8 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 VBB26935.1 - 5.1e-10 39.1 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 VBB26935.1 - 6.6e-08 32.7 11.2 0.00047 20.3 0.0 3.9 4 0 0 4 4 4 2 PHD-zinc-finger like domain Tudor_2 PF18104.1 VBB26935.1 - 1.6e-07 30.8 1.0 0.0002 21.0 0.4 2.9 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 VBB26935.1 - 3.8e-05 23.8 12.1 0.0079 16.4 1.0 3.6 2 1 1 3 3 3 2 PHD-like zinc-binding domain tRNA_m1G_MT PF01746.21 VBB26936.1 - 0.00033 20.4 0.2 0.0026 17.5 0.2 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ebp2 PF05890.12 VBB26937.1 - 4.6e-64 216.6 32.9 5.2e-64 216.4 32.9 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DASH_Dam1 PF08653.10 VBB26937.1 - 0.12 12.2 0.2 4.5 7.1 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Trans_reg_C PF00486.28 VBB26937.1 - 0.28 11.3 4.3 1.4 9.1 0.1 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal TTR-52 PF01060.23 VBB26938.1 - 5.6e-19 68.6 0.0 6.6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 VBB26939.1 - 3.2e-22 79.0 0.3 4.4e-22 78.6 0.3 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 VBB26939.1 - 0.045 13.8 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Cpn60_TCP1 PF00118.24 VBB26940.1 - 2e-88 297.2 14.2 3e-88 296.6 14.2 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TTR-52 PF01060.23 VBB26940.1 - 2.3e-21 76.3 0.1 6.2e-21 74.9 0.1 1.8 2 0 0 2 2 1 1 Transthyretin-like family FAD_binding_2 PF00890.24 VBB26940.1 - 7.9e-08 31.8 1.1 1.1e-05 24.7 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 VBB26940.1 - 9.8e-08 32.1 0.3 3.5e-07 30.4 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 VBB26940.1 - 1.1e-07 31.6 0.1 0.0013 18.1 0.1 3.1 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 VBB26940.1 - 3.2e-07 30.2 1.5 3.7e-05 23.5 0.8 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 VBB26940.1 - 1.7e-05 24.2 0.1 0.00056 19.2 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 VBB26940.1 - 0.00013 21.3 0.3 0.00022 20.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 VBB26940.1 - 0.00088 17.9 0.7 0.021 13.4 0.1 2.2 2 0 0 2 2 2 1 GDP dissociation inhibitor HI0933_like PF03486.14 VBB26940.1 - 0.0026 16.6 0.0 0.0056 15.4 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 VBB26940.1 - 0.0039 17.7 0.1 0.0039 17.7 0.1 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 VBB26940.1 - 0.099 12.0 0.2 2.6 7.4 0.1 2.5 2 0 0 2 2 2 0 GMC oxidoreductase Tli4_N PF18443.1 VBB26940.1 - 0.11 12.8 0.3 0.54 10.6 0.1 2.1 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain FAD_oxidored PF12831.7 VBB26940.1 - 0.13 11.6 2.5 0.33 10.3 1.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 VBB26940.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Cpn10 PF00166.21 VBB26941.1 - 4.2e-32 110.1 0.0 4.9e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit 4HBT PF03061.22 VBB26942.1 - 7e-16 58.3 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 VBB26942.1 - 1.1e-05 25.9 0.0 1.5e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 VBB26942.1 - 0.0022 18.4 0.0 0.0034 17.9 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 VBB26942.1 - 0.062 12.9 0.2 0.18 11.3 0.1 1.9 1 1 1 2 2 2 0 MaoC like domain DUF4442 PF14539.6 VBB26942.1 - 0.068 13.3 0.8 0.48 10.6 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4442) Cluap1 PF10234.9 VBB26943.1 - 4.7e-81 272.1 15.3 4.7e-81 272.1 15.3 1.6 1 1 1 2 2 2 1 Clusterin-associated protein-1 Ndc80_HEC PF03801.13 VBB26943.1 - 0.0075 15.9 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family NOA36 PF06524.12 VBB26943.1 - 0.99 8.7 10.9 1.7 7.9 10.9 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1515 PF07439.11 VBB26943.1 - 1.6 8.8 8.5 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) BUD22 PF09073.10 VBB26943.1 - 2.8 7.2 13.3 3.7 6.8 13.3 1.2 1 0 0 1 1 1 0 BUD22 FTCD_C PF04961.12 VBB26943.1 - 3.8 7.3 9.9 2.1 8.1 1.2 2.2 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase APG6_N PF17675.1 VBB26943.1 - 7.6 7.1 21.7 0.9 10.1 11.3 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region Y_phosphatase PF00102.27 VBB26944.1 - 1.4e-24 86.9 0.1 2.2e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BioT2 PF15368.6 VBB26945.1 - 0.081 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 GTP_EFTU PF00009.27 VBB26946.1 - 1.8e-52 177.7 0.0 2.8e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 VBB26946.1 - 4.5e-16 59.0 1.2 4.5e-16 59.0 1.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 VBB26946.1 - 7.7e-09 35.9 0.0 2.1e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 VBB26946.1 - 0.00052 20.1 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DDRGK PF09756.9 VBB26947.1 - 3.5e-56 189.8 31.2 3.5e-56 189.8 31.2 1.6 2 0 0 2 2 2 1 DDRGK domain FeoC PF09012.10 VBB26947.1 - 0.0056 16.7 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 FeoC like transcriptional regulator SLC12 PF03522.15 VBB26947.1 - 0.079 12.0 8.1 0.094 11.7 8.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Caldesmon PF02029.15 VBB26947.1 - 0.14 10.9 40.7 0.23 10.2 40.7 1.3 1 0 0 1 1 1 0 Caldesmon DDHD PF02862.17 VBB26947.1 - 0.28 11.3 2.3 0.36 11.0 2.3 1.3 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.10 VBB26947.1 - 0.54 10.6 18.5 0.89 9.9 18.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 VBB26947.1 - 1.6 8.5 19.7 2.1 8.1 19.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM178 PF14816.6 VBB26947.1 - 2.9 6.8 14.7 4.4 6.2 14.7 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 Presenilin PF01080.17 VBB26947.1 - 4.6 5.9 12.7 6.4 5.4 12.7 1.2 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 VBB26947.1 - 5 7.3 12.2 7.6 6.7 12.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family ALMT PF11744.8 VBB26947.1 - 8.7 5.0 7.5 11 4.8 7.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Pannexin_like PF12534.8 VBB26947.1 - 9.4 5.2 6.2 12 4.8 6.2 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 RRM_1 PF00076.22 VBB26948.1 - 1.1e-19 70.0 0.0 1.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB26948.1 - 0.087 12.7 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 VBB26948.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 RNA binding motif AF-4 PF05110.13 VBB26948.1 - 0.39 8.7 34.5 0.5 8.4 34.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ndc1_Nup PF09531.10 VBB26948.1 - 1.1 7.8 15.3 1.4 7.5 15.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup KRTAP PF11759.8 VBB26949.1 - 7.9 7.1 48.2 3.9 8.1 25.8 3.4 1 1 1 2 2 2 0 Keratin-associated matrix Brix PF04427.18 VBB26950.1 - 2.5e-26 93.0 0.8 2.5e-26 93.0 0.8 1.8 2 0 0 2 2 2 1 Brix domain DUF4629 PF15442.6 VBB26950.1 - 0.084 13.1 5.5 0.17 12.1 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) LMBR1 PF04791.16 VBB26950.1 - 0.32 9.9 1.8 0.42 9.5 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3959 PF13105.6 VBB26950.1 - 0.76 9.2 3.0 1.2 8.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) ALMT PF11744.8 VBB26950.1 - 1.8 7.3 3.7 2.6 6.8 3.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 VBB26951.1 - 4.8e-23 81.9 0.0 6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26951.1 - 5.1e-10 39.1 0.0 7.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB26951.1 - 7.2e-10 38.2 0.0 1.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB26951.1 - 0.056 13.4 0.1 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 VBB26951.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LBP_BPI_CETP PF01273.25 VBB26952.1 - 0.0081 15.8 0.7 0.021 14.4 0.7 1.8 1 1 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DB PF01682.19 VBB26953.1 - 6.1e-25 87.4 10.1 6.1e-25 87.4 10.1 1.8 2 0 0 2 2 2 1 DB module Tannase PF07519.11 VBB26953.1 - 0.046 12.6 0.9 0.061 12.2 0.9 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Pkinase PF00069.25 VBB26954.1 - 4.1e-21 75.5 0.0 4.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB26954.1 - 3.1e-13 49.6 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB26954.1 - 0.00016 20.6 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB26954.1 - 0.0026 17.7 0.0 0.055 13.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Lactamase_B_2 PF12706.7 VBB26955.1 - 9e-20 71.0 0.4 1.4e-18 67.1 0.2 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 VBB26955.1 - 2.4e-11 43.2 0.0 4.4e-10 39.1 0.0 2.7 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 VBB26955.1 - 1.1e-06 28.9 0.0 0.00011 22.3 0.0 3.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 VBB26955.1 - 0.095 12.6 0.6 3.3 7.6 0.6 2.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Ras PF00071.22 VBB26956.1 - 6.4e-54 181.9 0.0 7.7e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB26956.1 - 4.5e-28 97.9 0.0 6.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB26956.1 - 8.6e-16 57.9 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB26956.1 - 4.5e-07 30.0 0.0 7.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 VBB26956.1 - 1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 VBB26956.1 - 0.007 15.9 0.2 0.63 9.6 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB26956.1 - 0.0097 15.8 0.0 0.19 11.6 0.0 2.4 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 VBB26956.1 - 0.014 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 VBB26956.1 - 0.059 13.1 0.1 3 7.6 0.0 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 VBB26956.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 VBB26956.1 - 0.18 12.2 0.0 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Actin PF00022.19 VBB26957.1 - 1.7e-73 247.6 0.0 2.7e-72 243.6 0.0 1.9 1 1 0 1 1 1 1 Actin RRM_1 PF00076.22 VBB26958.1 - 4.7e-40 135.3 0.1 3.1e-20 71.8 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB26958.1 - 1.5e-06 27.8 0.0 0.016 14.8 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB26958.1 - 2e-06 27.9 0.1 0.0055 16.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 VBB26958.1 - 0.026 14.2 0.5 3.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 VBB26958.1 - 0.07 13.2 0.2 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Acyl_transf_3 PF01757.22 VBB26959.1 - 2.4e-16 59.7 44.0 3.9e-16 59.0 41.8 2.0 2 0 0 2 2 2 1 Acyltransferase family Tmemb_9 PF05434.11 VBB26959.1 - 0.25 11.2 2.3 11 5.9 0.3 2.7 2 0 0 2 2 2 0 TMEM9 EF-hand_like PF09279.11 VBB26960.1 - 0.087 13.3 0.4 0.56 10.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like MOZ_SAS PF01853.18 VBB26961.1 - 4.1e-78 261.1 0.1 6.7e-78 260.4 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 VBB26961.1 - 4.5e-22 77.4 5.2 1.2e-21 76.1 5.2 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 VBB26961.1 - 2.7e-13 49.6 0.6 6.3e-13 48.4 0.1 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 VBB26961.1 - 0.006 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_7 PF13508.7 VBB26961.1 - 0.0094 16.4 0.0 0.039 14.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 VBB26961.1 - 0.092 12.7 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein fn3 PF00041.21 VBB26962.1 - 1.5e-41 140.6 32.0 2.8e-10 40.4 0.3 6.4 6 0 0 6 6 6 6 Fibronectin type III domain DB PF01682.19 VBB26962.1 - 8e-37 125.5 100.6 7.6e-13 48.6 11.5 6.8 5 2 1 6 6 5 5 DB module I-set PF07679.16 VBB26962.1 - 1.5e-14 53.8 3.0 1.5e-07 31.4 0.0 4.9 5 1 0 5 5 5 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB26962.1 - 7.2e-13 49.0 4.9 1.7e-05 25.3 0.0 5.5 4 1 0 4 4 4 2 Immunoglobulin domain Lustrin_cystein PF14625.6 VBB26962.1 - 6.6e-08 32.8 9.0 6.6e-08 32.8 9.0 4.8 5 0 0 5 5 2 1 Lustrin, cysteine-rich repeated domain Ig_2 PF13895.6 VBB26962.1 - 5.8e-07 29.8 1.8 0.25 11.7 0.0 4.5 4 0 0 4 4 4 2 Immunoglobulin domain fn3_2 PF16893.5 VBB26962.1 - 7.5e-06 26.0 0.2 0.19 11.9 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain ig PF00047.25 VBB26962.1 - 1.6e-05 25.0 6.6 0.013 15.6 0.0 3.1 3 0 0 3 3 2 2 Immunoglobulin domain V-set PF07686.17 VBB26962.1 - 4.4e-05 23.6 3.7 0.0071 16.5 0.0 4.7 4 2 1 5 5 5 1 Immunoglobulin V-set domain Interfer-bind PF09294.10 VBB26962.1 - 5e-05 23.6 18.0 0.019 15.2 0.1 5.8 6 0 0 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 VBB26962.1 - 0.00071 19.6 0.1 0.0026 17.8 0.1 1.9 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Glyco_hydro_36C PF16874.5 VBB26962.1 - 0.0062 17.0 0.0 13 6.3 0.0 3.9 4 0 0 4 4 4 0 Glycosyl hydrolase family 36 C-terminal domain Pur_ac_phosph_N PF16656.5 VBB26962.1 - 0.12 13.0 31.7 0.84 10.2 0.2 6.8 5 2 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain Adeno_E3_CR1 PF02440.15 VBB26962.1 - 0.37 10.6 3.6 2.2 8.1 1.7 3.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 RIC3 PF15361.6 VBB26963.1 - 1.5e-30 106.5 0.1 1.5e-30 106.5 0.1 2.2 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 LMBR1 PF04791.16 VBB26963.1 - 0.0032 16.4 0.0 0.0036 16.3 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein ATG27 PF09451.10 VBB26963.1 - 0.011 15.7 0.8 0.046 13.6 0.0 2.1 2 0 0 2 2 2 0 Autophagy-related protein 27 CcmH PF03918.14 VBB26963.1 - 0.056 12.7 0.4 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein ECF_trnsprt PF12822.7 VBB26963.1 - 0.069 13.2 0.2 7.2 6.7 0.2 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component 7TM_GPCR_Srw PF10324.9 VBB26963.1 - 0.16 11.2 0.1 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF4400 PF14348.6 VBB26963.1 - 0.92 9.0 4.7 4.5 6.7 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4400) FeoB_associated PF12669.7 VBB26963.1 - 1.6 9.2 3.4 1.9 8.9 0.2 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein TMPIT PF07851.13 VBB26963.1 - 5.9 6.0 8.2 10 5.2 8.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin_2 PF14523.6 VBB26963.1 - 7 7.1 11.4 1.4 9.4 6.9 1.9 1 1 1 2 2 2 0 Syntaxin-like protein UPF0242 PF06785.11 VBB26963.1 - 7.3 6.6 15.5 4.3 7.4 13.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CTP_transf_1 PF01148.20 VBB26964.1 - 4.1e-78 262.8 28.0 5.4e-78 262.4 28.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Mito_carr PF00153.27 VBB26965.1 - 5.1e-70 231.5 0.2 5.4e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Caveolin PF01146.17 VBB26966.1 - 7e-31 106.9 0.6 1e-30 106.4 0.6 1.1 1 0 0 1 1 1 1 Caveolin SLATT_5 PF18160.1 VBB26966.1 - 0.03 13.6 0.3 0.03 13.6 0.3 1.6 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PFL-like PF02901.15 VBB26966.1 - 0.04 12.5 0.2 0.052 12.2 0.2 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like DUF2207 PF09972.9 VBB26966.1 - 0.046 12.5 0.2 0.06 12.1 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ca_chan_IQ PF08763.11 VBB26966.1 - 0.065 13.5 0.6 0.065 13.5 0.6 1.8 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain LBP_BPI_CETP PF01273.25 VBB26968.1 - 3.1e-13 49.7 1.1 7.7e-13 48.4 0.0 2.2 3 1 1 4 4 4 1 LBP / BPI / CETP family, N-terminal domain G8 PF10162.9 VBB26968.1 - 0.038 14.1 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 G8 domain OstA PF03968.14 VBB26968.1 - 0.1 12.8 0.1 0.75 10.0 0.1 2.2 1 1 0 1 1 1 0 OstA-like protein LBP_BPI_CETP_C PF02886.17 VBB26969.1 - 1.5e-21 77.0 0.1 2.2e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 VBB26969.1 - 2.5e-10 40.2 0.0 8.7e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain PDZ PF00595.24 VBB26970.1 - 5.9e-26 90.6 3.0 1.4e-08 35.0 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 VBB26970.1 - 2.8e-14 52.7 1.3 0.00033 20.4 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 VBB26970.1 - 3e-09 37.1 0.2 0.00034 20.9 0.0 4.0 3 0 0 3 3 3 2 PDZ domain Par3_HAL_N_term PF12053.8 VBB26970.1 - 1.1e-07 32.0 0.2 3e-07 30.6 0.2 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Penaeidin PF05927.11 VBB26971.1 - 0.05 14.4 2.7 1.4 9.7 0.4 2.3 2 0 0 2 2 2 0 Penaeidin Baculo_p74 PF04583.12 VBB26972.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region zf-RING_UBOX PF13445.6 VBB26973.1 - 0.0023 17.9 3.7 0.0061 16.5 3.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB26973.1 - 0.0038 17.1 4.7 0.0038 17.1 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB26973.1 - 0.0083 15.9 5.2 0.0083 15.9 5.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB26973.1 - 0.0085 16.0 7.4 0.0085 16.0 7.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 VBB26973.1 - 5.9 7.3 14.1 0.23 11.8 7.6 2.0 2 0 0 2 2 2 0 Ring finger domain CBS PF00571.28 VBB26974.1 - 2.5e-32 111.1 1.7 3.7e-12 46.5 1.9 4.4 4 0 0 4 4 4 4 CBS domain DDE_2 PF02914.15 VBB26974.1 - 0.37 10.5 0.8 28 4.3 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage Mu transposase Synaptobrevin PF00957.21 VBB26975.1 - 2.9e-25 87.9 5.4 3.3e-25 87.7 5.4 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF2721 PF11026.8 VBB26975.1 - 0.0032 17.4 1.3 0.0038 17.1 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Spc7 PF08317.11 VBB26975.1 - 0.02 13.8 2.3 0.022 13.7 2.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein MCU PF04678.13 VBB26975.1 - 0.055 13.6 1.9 0.065 13.3 1.9 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Arm PF00514.23 VBB26976.1 - 6.7e-09 35.5 0.2 0.002 18.1 0.1 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Plasmodium_HRP PF05403.11 VBB26976.1 - 0.0057 16.5 8.3 0.011 15.5 8.3 1.4 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) BUD22 PF09073.10 VBB26976.1 - 6.7 5.9 15.9 10 5.3 15.9 1.2 1 0 0 1 1 1 0 BUD22 Sec7 PF01369.20 VBB26977.1 - 1.2e-66 223.9 0.0 1.5e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 VBB26977.1 - 9.7e-23 80.7 0.2 1.8e-22 79.9 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 VBB26977.1 - 0.00031 21.1 0.2 0.00061 20.2 0.2 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 VBB26977.1 - 0.024 14.9 0.0 0.16 12.3 0.0 2.2 1 1 0 2 2 2 0 Pleckstrin homology domain zf-SNAP50_C PF12251.8 VBB26978.1 - 0.15 11.8 0.7 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal O-FucT PF10250.9 VBB26979.1 - 4e-66 224.0 0.5 4.8e-66 223.8 0.5 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3247 PF11607.8 VBB26979.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Ribosomal_S5 PF00333.20 VBB26980.1 - 3.6e-30 103.8 0.8 6.5e-30 102.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 VBB26980.1 - 5.8e-25 86.6 0.0 9.4e-25 85.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HSP70 PF00012.20 VBB26981.1 - 1.4e-83 281.1 10.1 1.4e-83 281.1 10.1 3.1 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 VBB26981.1 - 0.0064 15.4 2.9 0.052 12.4 0.2 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FGF PF00167.18 VBB26982.1 - 1.6e-16 60.6 0.3 2.3e-16 60.0 0.3 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Ion_trans_2 PF07885.16 VBB26983.1 - 8.3e-12 44.9 5.2 4.9e-07 29.6 0.1 3.2 3 0 0 3 3 3 2 Ion channel TPPK_C PF12555.8 VBB26983.1 - 5.2 7.2 6.8 2.2 8.4 0.7 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Sec3_C PF09763.9 VBB26984.1 - 4.1e-109 366.0 12.9 5.7e-109 365.5 12.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 VBB26984.1 - 1.1e-17 63.9 0.5 3.5e-17 62.3 0.3 2.0 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH PF00169.29 VBB26984.1 - 0.021 15.3 0.1 0.069 13.7 0.1 1.8 1 0 0 1 1 1 0 PH domain Inositol_P PF00459.25 VBB26985.1 - 5.3e-08 32.7 0.0 5.9e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family eIF2_C PF09173.11 VBB26986.1 - 7e-37 125.6 0.5 1.6e-36 124.4 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 VBB26986.1 - 1.6e-22 80.0 0.2 1.1e-21 77.3 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 VBB26986.1 - 5.9e-11 42.6 1.0 2.8e-10 40.4 0.5 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 VBB26986.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB26986.1 - 0.002 18.1 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase DNA_ligase_ZBD PF03119.16 VBB26986.1 - 0.014 15.4 0.8 0.058 13.4 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain G-alpha PF00503.20 VBB26986.1 - 0.057 12.6 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 VBB26986.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Mannosyl_trans2 PF04188.13 VBB26987.1 - 9.3e-20 71.4 14.3 3.5e-14 53.0 12.4 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) DUF2070 PF09843.9 VBB26987.1 - 2.5 6.3 9.7 3.5 5.8 9.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HEAT PF02985.22 VBB26988.1 - 2.8e-11 42.6 7.0 0.19 12.1 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 VBB26988.1 - 1e-08 35.4 5.5 0.002 18.5 0.3 4.5 2 2 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 VBB26988.1 - 2.4e-07 30.9 0.6 0.017 15.1 0.0 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 VBB26988.1 - 0.011 15.9 0.2 8.8 6.6 0.0 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 VBB26988.1 - 0.036 14.6 3.4 23 5.6 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat HEAT_PBS PF03130.16 VBB26988.1 - 0.11 13.3 1.3 57 4.8 0.1 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Iso_dh PF00180.20 VBB26989.1 - 1.2e-78 264.7 0.0 1.4e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 VBB26989.1 - 0.17 12.6 0.8 4.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Phenylalanine zipper UPF1_Zn_bind PF09416.10 VBB26990.1 - 5.2e-69 231.1 7.4 9.9e-69 230.1 3.1 3.1 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 VBB26990.1 - 4e-59 199.6 0.0 7.8e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 VBB26990.1 - 6.7e-41 140.8 16.3 1e-21 77.9 2.8 3.9 3 1 1 4 4 4 2 AAA domain Methyltr_RsmB-F PF01189.17 VBB26990.1 - 2.6e-37 128.4 2.0 1.8e-36 125.7 0.0 3.3 3 1 0 3 3 3 1 16S rRNA methyltransferase RsmB/F DEAD PF00270.29 VBB26990.1 - 1.8e-30 106.0 0.1 3.1e-25 88.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF5599 PF18141.1 VBB26990.1 - 2.5e-28 98.1 0.0 5.9e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) Helicase_C PF00271.31 VBB26990.1 - 7.8e-25 87.4 0.2 7.7e-24 84.2 0.0 2.8 4 0 0 4 4 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB26990.1 - 2.7e-15 56.8 0.0 6.4e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 VBB26990.1 - 8.2e-15 55.0 0.1 6.7e-14 52.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 VBB26990.1 - 1e-12 48.6 0.8 7.9e-12 45.7 0.5 2.4 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 VBB26990.1 - 0.00034 20.5 0.1 0.0012 18.7 0.0 2.1 2 0 0 2 2 1 1 Helicase DUF2075 PF09848.9 VBB26990.1 - 0.00064 19.1 0.1 0.013 14.7 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 VBB26990.1 - 0.00068 19.4 1.2 1.7 8.3 0.0 3.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 VBB26990.1 - 0.0012 19.1 0.0 0.33 11.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 VBB26990.1 - 0.0034 17.8 0.2 0.0098 16.3 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 VBB26990.1 - 0.0047 16.5 2.4 0.035 13.6 0.0 2.9 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 VBB26990.1 - 0.025 14.0 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 VBB26990.1 - 0.031 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.7 VBB26990.1 - 0.04 12.8 0.0 0.098 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain FtsJ PF01728.19 VBB26990.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase AAA PF00004.29 VBB26990.1 - 0.043 14.2 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 VBB26990.1 - 0.051 12.9 0.7 0.3 10.4 0.0 2.6 3 0 0 3 3 3 0 KaiC UvrD_C_2 PF13538.6 VBB26990.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ubiquitin PF00240.23 VBB26993.1 - 5.9e-28 96.4 0.2 6.5e-28 96.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 VBB26993.1 - 2.7e-15 56.0 0.2 2.9e-15 55.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 VBB26993.1 - 3.4e-05 24.2 0.0 0.0001 22.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 VBB26993.1 - 0.00028 20.7 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 VBB26993.1 - 0.027 14.6 0.1 0.079 13.1 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like IMD PF08397.11 VBB26995.1 - 1.4e-32 112.9 0.9 4.9e-28 98.0 0.3 2.2 1 1 1 2 2 2 2 IRSp53/MIM homology domain Armet PF10208.9 VBB26995.1 - 0.048 13.6 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding DUF4736 PF15883.5 VBB26995.1 - 0.061 13.0 0.3 0.26 11.0 0.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4736) Caskin-Pro-rich PF16907.5 VBB26995.1 - 0.14 12.7 3.3 0.61 10.7 0.1 2.8 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Mito_carr PF00153.27 VBB26996.1 - 2.2e-54 181.3 3.9 3.7e-20 71.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Clc-like PF07062.12 VBB26997.1 - 6.9e-71 238.1 7.0 8.1e-71 237.9 7.0 1.0 1 0 0 1 1 1 1 Clc-like SUR7 PF06687.12 VBB26997.1 - 3.8e-05 23.4 5.6 9.9e-05 22.1 5.6 1.7 1 1 0 1 1 1 1 SUR7/PalI family PMP22_Claudin PF00822.20 VBB26997.1 - 0.0003 20.7 8.5 0.004 17.1 0.0 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family IBR PF01485.21 VBB26998.1 - 8.1e-07 29.2 42.5 4.9e-06 26.7 7.4 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain UPRTase PF14681.6 VBB26999.1 - 4.1e-42 144.0 0.0 6.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 VBB26999.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain SH3BGR PF04908.15 VBB27000.1 - 4.3e-18 65.3 2.9 4.3e-18 65.3 0.1 2.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 VBB27000.1 - 0.0012 19.1 0.0 0.0033 17.6 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin PBP PF01161.20 VBB27001.1 - 4.5e-06 27.0 0.0 8.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.32 VBB27002.1 - 2.6e-32 110.3 6.0 3e-09 37.3 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 VBB27002.1 - 8.6e-22 77.8 0.3 2.2e-21 76.4 0.3 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Acetyltransf_1 PF00583.25 VBB27002.1 - 3.1e-13 50.0 0.0 2.2e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family ANAPC4_WD40 PF12894.7 VBB27002.1 - 1.4e-09 38.1 0.0 0.36 11.1 0.0 5.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_7 PF13508.7 VBB27002.1 - 9.2e-09 35.6 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 VBB27002.1 - 8e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 VBB27002.1 - 0.0001 22.2 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 VBB27002.1 - 0.00012 22.2 0.0 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ge1_WD40 PF16529.5 VBB27002.1 - 0.0015 17.5 0.0 1.1 8.2 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 VBB27002.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 LisH FA_desaturase_2 PF03405.14 VBB27002.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase WD40 PF00400.32 VBB27003.1 - 2.1e-20 72.6 0.9 2e-05 25.3 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27003.1 - 4.8e-10 39.6 0.0 0.00093 19.4 0.0 4.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 VBB27003.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 PQQ-like domain PD40 PF07676.12 VBB27003.1 - 0.031 14.2 0.3 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 VBB27003.1 - 0.1 11.2 0.1 3 6.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Adaptin_N PF01602.20 VBB27004.1 - 9.4e-144 479.8 14.7 1.1e-143 479.5 14.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 VBB27004.1 - 2.3e-14 53.7 8.6 4.8e-13 49.5 0.1 3.9 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 VBB27004.1 - 2.2e-11 44.2 0.1 5.6e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 VBB27004.1 - 5.5e-07 29.9 5.6 0.011 16.2 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 VBB27004.1 - 0.00044 20.7 4.8 3.5 8.2 0.1 4.8 4 0 0 4 4 4 1 HEAT-like repeat DUF719 PF05334.13 VBB27004.1 - 0.011 15.9 0.6 0.024 14.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Afi1 PF07792.12 VBB27004.1 - 0.014 15.9 6.2 0.025 15.1 6.2 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPP4R2 PF09184.11 VBB27004.1 - 0.067 12.8 15.1 0.11 12.1 15.1 1.2 1 0 0 1 1 1 0 PPP4R2 HEAT PF02985.22 VBB27004.1 - 0.075 13.3 13.8 0.86 10.0 0.0 6.2 7 0 0 7 7 7 0 HEAT repeat Drc1-Sld2 PF11719.8 VBB27004.1 - 0.091 12.3 7.9 0.14 11.7 7.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Zip PF02535.22 VBB27004.1 - 0.43 9.8 1.6 0.68 9.1 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 VBB27004.1 - 0.48 9.8 20.6 0.73 9.2 20.6 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 VBB27004.1 - 2.6 8.5 5.4 5.7 7.4 5.4 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 VBB27004.1 - 3.1 5.8 26.7 6.8 4.7 26.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 VBB27004.1 - 4.8 5.6 16.4 0.52 8.8 11.6 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF21 PF01595.20 VBB27005.1 - 7e-26 91.0 0.7 1.2e-25 90.2 0.7 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 VBB27005.1 - 1.4e-06 28.6 2.1 0.0026 18.2 0.6 2.8 2 0 0 2 2 2 2 CBS domain TPR_1 PF00515.28 VBB27011.1 - 3.9e-06 26.4 13.1 0.0019 18.0 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27011.1 - 9.1e-06 25.8 4.1 0.00037 20.6 0.2 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 VBB27011.1 - 0.00014 21.8 3.7 0.02 15.1 0.5 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27011.1 - 0.0013 18.7 10.7 0.089 13.0 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB27011.1 - 0.0029 18.1 4.1 0.033 14.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB27011.1 - 0.013 15.6 0.3 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 VBB27011.1 - 0.22 12.2 5.6 0.63 10.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 VBB27011.1 - 0.26 11.4 2.7 1.7 8.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB27011.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Y_phosphatase PF00102.27 VBB27012.1 - 3.2e-66 223.3 1.6 5.7e-65 219.2 1.0 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB27012.1 - 0.00035 20.6 0.0 0.00083 19.4 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 VBB27012.1 - 0.00084 19.2 0.2 0.0024 17.7 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB27012.1 - 0.11 12.6 0.4 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Phi-29_GP16_7 PF06720.11 VBB27012.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 PAX PF00292.18 VBB27013.1 - 3.4e-15 56.1 0.1 5.8e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 VBB27013.1 - 9.3e-09 34.8 0.1 1.5e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 VBB27013.1 - 2e-08 33.9 0.3 4.1e-08 32.8 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 VBB27013.1 - 1.1e-05 25.4 0.2 2e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 VBB27013.1 - 2e-05 24.6 0.1 3.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 VBB27013.1 - 0.00056 19.8 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.13 VBB27013.1 - 0.0099 15.5 0.2 0.092 12.4 0.1 2.3 1 1 1 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 VBB27013.1 - 0.029 14.4 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_40 PF14493.6 VBB27013.1 - 0.056 13.9 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 VBB27013.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Transposase HLH PF00010.26 VBB27014.1 - 3.3e-11 43.0 2.9 8.1e-11 41.7 2.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.8 VBB27014.1 - 0.061 14.1 0.0 0.19 12.5 0.0 2.0 1 0 0 1 1 1 0 Myogenic determination factor 5 p450 PF00067.22 VBB27015.1 - 2.7e-74 250.6 0.9 1e-59 202.5 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 Sec1 PF00995.23 VBB27016.1 - 4.5e-29 102.1 1.1 5.4e-29 101.9 1.1 1.0 1 0 0 1 1 1 1 Sec1 family R3H PF01424.22 VBB27017.1 - 5e-16 58.4 0.0 1.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 VBB27017.1 - 9.7e-07 28.7 28.9 3e-05 24.0 10.0 13.4 12 3 0 12 12 12 4 NF-X1 type zinc finger LRR_6 PF13516.6 VBB27018.1 - 1.3e-23 81.0 28.6 0.022 14.8 0.0 13.8 15 0 0 15 15 15 8 Leucine Rich repeat LRR_4 PF12799.7 VBB27018.1 - 5.8e-13 48.8 15.8 0.47 11.0 0.0 9.0 7 3 4 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 VBB27018.1 - 9.5e-09 34.9 27.2 0.067 13.0 0.1 9.8 7 4 0 7 7 7 3 Leucine rich repeat LRR_1 PF00560.33 VBB27018.1 - 7e-08 32.0 8.3 12 6.9 0.3 10.6 11 0 0 11 11 11 1 Leucine Rich Repeat TBD PF12845.7 VBB27018.1 - 0.13 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 TBD domain PUA PF01472.20 VBB27018.1 - 0.45 10.5 2.2 14 5.7 0.1 2.9 2 0 0 2 2 2 0 PUA domain AMP-binding PF00501.28 VBB27020.1 - 2.2e-89 300.0 0.0 8.7e-89 298.0 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB27020.1 - 4e-16 59.7 0.1 8.6e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBFD_NFYB_HMF PF00808.23 VBB27020.1 - 1.8e-09 37.7 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB27020.1 - 0.00044 20.6 0.0 0.00091 19.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DHHC PF01529.20 VBB27020.1 - 0.0032 17.6 2.8 0.0038 17.3 0.5 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase zf-C2H2 PF00096.26 VBB27021.1 - 2.3e-14 53.0 38.4 0.0034 17.7 0.1 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB27021.1 - 3.3e-14 52.4 40.0 0.037 14.9 1.1 7.9 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB27021.1 - 5.2e-07 29.8 21.9 0.0016 18.7 0.2 6.6 7 0 0 7 7 6 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 VBB27021.1 - 8.6e-05 22.3 0.0 8.6e-05 22.3 0.0 5.6 7 0 0 7 7 7 2 zinc-finger of a C2HC-type CpXC PF14353.6 VBB27021.1 - 0.0017 18.4 15.7 0.41 10.7 2.9 5.2 4 2 1 5 5 5 2 CpXC protein zf-C2H2_2 PF12756.7 VBB27021.1 - 0.012 15.9 16.2 20 5.6 0.2 6.6 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 VBB27021.1 - 0.037 14.3 23.6 1.1 9.6 0.1 6.4 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 VBB27021.1 - 0.04 14.7 6.8 5.4 7.8 0.1 4.0 4 0 0 4 4 3 0 zinc-ribbon family zf-met PF12874.7 VBB27021.1 - 0.072 13.5 24.3 6.7 7.3 1.0 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 VBB27021.1 - 0.081 12.7 3.8 0.41 10.4 0.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 VBB27021.1 - 0.13 12.6 23.3 0.12 12.7 2.4 4.9 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 VBB27021.1 - 0.77 10.3 17.6 4 8.0 0.1 5.9 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 VBB27021.1 - 1.8 9.2 14.5 2.7 8.7 0.2 4.2 5 0 0 5 5 4 0 Zinc finger C2H2-type, 3 repeats Vps36-NZF-N PF16988.5 VBB27021.1 - 2.1 7.8 6.7 1.9 7.9 0.1 3.2 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_9 PF16293.5 VBB27021.1 - 9.1 6.2 8.7 59 3.6 0.2 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF938 PF06080.12 VBB27022.1 - 1.2e-60 204.7 0.0 1.7e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Kelch_1 PF01344.25 VBB27022.1 - 3.7e-17 61.6 4.5 0.004 16.7 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 VBB27022.1 - 1.1e-14 54.1 4.9 0.0076 16.5 0.0 6.6 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 VBB27022.1 - 5.4e-13 48.7 10.5 0.0052 16.8 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 VBB27022.1 - 3.6e-11 43.1 0.3 0.064 13.6 0.0 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 VBB27022.1 - 1.1e-05 25.2 9.3 0.18 11.8 0.5 5.3 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 VBB27022.1 - 6.7e-05 22.7 8.3 0.52 10.4 0.0 5.7 6 0 0 6 6 6 1 Kelch motif Methyltransf_25 PF13649.6 VBB27022.1 - 0.041 14.6 0.0 0.086 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Bestrophin PF01062.21 VBB27023.1 - 3.3e-61 207.3 12.5 1.6e-59 201.7 6.7 3.1 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel Lectin_C PF00059.21 VBB27023.1 - 1.2e-10 42.0 3.6 4.7e-10 40.2 3.6 2.1 1 0 0 1 1 1 1 Lectin C-type domain DSPc PF00782.20 VBB27024.1 - 1.3e-23 83.2 0.1 2.1e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB27024.1 - 3.1e-05 23.7 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 VBB27024.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Glyco_hydro_47 PF01532.20 VBB27025.1 - 1.8e-114 383.1 0.0 7.2e-114 381.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 ATP-gua_Ptrans PF00217.19 VBB27025.1 - 9.2e-21 74.3 0.1 9.8e-19 67.7 0.0 2.4 1 1 1 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain PA PF02225.22 VBB27025.1 - 8.3e-10 38.6 0.0 2.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 PA domain ATP-gua_PtransN PF02807.15 VBB27025.1 - 1.1e-09 38.5 0.3 2.4e-09 37.5 0.3 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4105 PF13387.6 VBB27025.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) C5-epim_C PF06662.13 VBB27025.1 - 0.025 14.1 0.9 11 5.5 0.0 3.4 4 0 0 4 4 4 0 D-glucuronyl C5-epimerase C-terminus CENP-B_dimeris PF09026.10 VBB27025.1 - 0.11 12.9 6.1 0.36 11.2 6.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 VBB27025.1 - 6.4 6.4 7.2 15 5.2 7.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VRR_NUC PF08774.11 VBB27028.1 - 4.3e-24 84.7 0.0 1.3e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain Flavoprotein PF02441.19 VBB27030.1 - 6.1e-44 149.6 0.0 8.9e-44 149.0 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein ChaC PF04752.12 VBB27030.1 - 3.8e-43 147.6 0.0 7.4e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein FERM_M PF00373.18 VBB27031.1 - 3.7e-06 27.3 0.0 5.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 FERM central domain RdRP PF05183.12 VBB27032.1 - 1.9e-150 502.4 0.0 3.1e-150 501.6 0.0 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase WD40 PF00400.32 VBB27032.1 - 2.2e-26 91.6 17.6 5.1e-07 30.3 0.0 8.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27032.1 - 1.5e-12 47.6 2.7 0.00035 20.8 0.0 5.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB27032.1 - 7.4e-05 21.9 0.1 0.021 13.8 0.0 3.5 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SRP_TPR_like PF17004.5 VBB27033.1 - 1.1e-24 86.7 11.7 4.9e-21 74.9 2.3 4.3 3 2 1 4 4 4 2 Putative TPR-like repeat SRP72 PF08492.12 VBB27033.1 - 5.6e-18 65.1 9.6 5.6e-18 65.1 9.6 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 VBB27033.1 - 1.1e-13 50.2 16.9 0.0087 16.1 0.0 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 VBB27033.1 - 3.1e-12 46.8 27.7 0.0039 17.7 0.1 8.0 3 3 3 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 VBB27033.1 - 2.2e-10 40.5 13.7 0.45 11.3 0.1 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB27033.1 - 4e-10 39.9 22.9 0.058 13.7 2.5 8.0 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27033.1 - 6.3e-09 35.4 16.6 6e-05 22.9 0.1 7.8 7 1 1 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27033.1 - 1.9e-08 34.4 22.3 0.013 15.7 0.8 6.2 6 2 1 7 7 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 VBB27033.1 - 2e-07 31.2 16.9 0.36 11.8 0.0 9.4 7 3 3 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB27033.1 - 0.00011 22.8 7.0 4.1 8.1 0.1 6.4 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB27033.1 - 0.00011 21.8 15.6 0.58 10.1 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat SPO22 PF08631.10 VBB27033.1 - 0.00012 21.6 14.2 0.0041 16.6 0.1 3.8 2 2 1 5 5 5 2 Meiosis protein SPO22/ZIP4 like NARP1 PF12569.8 VBB27033.1 - 0.00049 19.2 20.5 0.056 12.4 0.6 4.7 3 2 2 5 5 4 3 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 VBB27033.1 - 0.0016 18.3 5.6 0.14 12.2 0.0 5.8 7 1 0 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.17 VBB27033.1 - 0.0072 16.8 14.7 0.14 12.6 0.1 4.7 5 2 1 6 6 4 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 VBB27033.1 - 0.012 16.1 0.3 1.1e+02 3.9 0.0 4.8 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 VBB27033.1 - 0.013 15.7 10.6 0.066 13.4 0.0 5.4 7 1 1 8 8 5 0 Tetratricopeptide repeat RPN7 PF10602.9 VBB27033.1 - 0.032 14.0 6.6 1.6 8.4 0.1 3.9 2 2 0 3 3 3 0 26S proteasome subunit RPN7 Coatomer_E PF04733.14 VBB27033.1 - 0.038 13.4 14.5 0.21 11.0 1.7 4.7 1 1 1 4 4 4 0 Coatomer epsilon subunit Rapsyn_N PF10579.9 VBB27033.1 - 0.043 13.9 0.2 20 5.4 0.0 4.1 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.6 VBB27033.1 - 0.049 13.5 8.4 31 4.6 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat YfdX PF10938.8 VBB27033.1 - 0.16 11.9 4.2 41 4.1 0.0 3.7 2 1 0 2 2 2 0 YfdX protein ChAPs PF09295.10 VBB27033.1 - 0.2 10.6 6.0 0.64 8.9 1.3 3.3 2 2 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 VBB27033.1 - 0.99 9.5 8.3 9.3 6.4 0.0 5.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Ribosomal_L22 PF00237.19 VBB27033.1 - 1.2 9.5 3.7 3.2 8.0 0.4 3.1 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e TPR_11 PF13414.6 VBB27033.1 - 1.2 8.9 11.2 26 4.6 0.0 6.6 8 0 0 8 8 8 0 TPR repeat PknG_TPR PF16918.5 VBB27033.1 - 1.2 7.7 7.9 1.5 7.5 0.1 3.6 2 1 1 4 4 4 0 Protein kinase G tetratricopeptide repeat DUF4398 PF14346.6 VBB27033.1 - 1.7 9.3 6.5 0.59 10.8 0.1 3.2 4 0 0 4 4 2 0 Domain of unknown function (DUF4398) Picorna_P3A PF06363.11 VBB27034.1 - 0.11 12.4 3.2 0.32 10.9 0.6 3.1 2 1 1 3 3 3 0 Picornaviridae P3A protein SLATT_6 PF18169.1 VBB27034.1 - 1.6 8.3 12.1 0.53 9.9 2.4 3.6 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 Holin_SPP1 PF04688.13 VBB27034.1 - 1.7 8.9 5.0 2.1 8.6 1.9 2.8 2 0 0 2 2 2 0 SPP1 phage holin RabGAP-TBC PF00566.18 VBB27035.1 - 1.3e-17 64.2 2.7 1.7e-17 63.8 0.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Lactamase_B PF00753.27 VBB27036.1 - 1.2e-15 58.1 0.2 3.7e-07 30.3 0.0 2.1 1 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB27036.1 - 0.025 14.1 0.2 0.047 13.2 0.1 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ERCC4 PF02732.15 VBB27037.1 - 9.1e-18 64.9 0.0 3.3e-17 63.1 0.0 2.1 1 0 0 1 1 1 1 ERCC4 domain SpoIISB_antitox PF14185.6 VBB27037.1 - 0.18 11.7 1.8 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF846 PF05832.12 VBB27039.1 - 1.6e-36 125.4 4.4 2.2e-36 124.9 4.4 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Actin PF00022.19 VBB27040.1 - 5.5e-115 384.2 0.0 5.5e-115 384.2 0.0 3.5 3 1 0 3 3 3 1 Actin NRDE-2 PF08424.10 VBB27040.1 - 2.5e-61 207.6 4.2 2.5e-61 207.6 4.2 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Ribosomal_S13 PF00416.22 VBB27040.1 - 2.3e-52 176.7 1.0 2.3e-52 176.7 1.0 4.1 3 1 1 4 4 4 1 Ribosomal protein S13/S18 HTH_12 PF08461.10 VBB27040.1 - 0.035 14.0 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF3989 PF13150.6 VBB27041.1 - 0.006 16.3 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3989) vATP-synt_E PF01991.18 VBB27042.1 - 3.3e-66 222.5 10.0 3.8e-66 222.3 10.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit zf-CRD PF17979.1 VBB27042.1 - 0.42 10.7 2.1 11 6.1 0.0 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions TFIIS_C PF01096.18 VBB27043.1 - 1.6e-15 56.6 11.3 2.5e-14 52.8 2.9 3.1 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 VBB27043.1 - 1.2e-13 50.7 4.7 1.2e-13 50.7 4.7 1.8 2 0 0 2 2 1 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.6 VBB27043.1 - 0.00056 20.4 4.2 0.0012 19.3 0.2 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 VBB27043.1 - 0.0083 16.5 0.8 0.0083 16.5 0.8 2.3 2 0 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.7 VBB27043.1 - 0.017 15.1 2.0 0.017 15.1 2.0 2.4 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_11 PF11682.8 VBB27043.1 - 0.041 13.9 1.5 1.8 8.6 0.4 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon Zn_Tnp_IS1595 PF12760.7 VBB27043.1 - 0.14 12.1 9.3 0.88 9.6 1.1 2.5 2 2 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 VBB27043.1 - 0.73 9.4 8.7 5.6 6.6 0.1 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding zf-C4_Topoisom PF01396.19 VBB27043.1 - 0.85 9.5 11.4 0.11 12.3 1.4 2.9 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger RecR PF02132.15 VBB27043.1 - 1.2 8.8 8.9 13 5.5 3.8 3.1 2 1 1 3 3 3 0 RecR protein CpXC PF14353.6 VBB27043.1 - 2.4 8.2 9.9 1.1 9.4 0.6 2.8 1 1 2 3 3 3 0 CpXC protein zf-IS66 PF13005.7 VBB27043.1 - 8.3 6.9 9.8 10 6.6 0.3 3.4 2 2 1 3 3 3 0 zinc-finger binding domain of transposase IS66 Ogr_Delta PF04606.12 VBB27043.1 - 8.5 6.4 17.5 0.36 10.9 4.0 3.4 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Robl_LC7 PF03259.17 VBB27044.1 - 1.2e-07 31.4 0.1 1.9e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain dCache_1 PF02743.18 VBB27044.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Cache domain TACC_C PF05010.14 VBB27045.1 - 6.5e-25 88.1 8.4 6.5e-25 88.1 8.4 3.0 3 0 0 3 3 3 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SOAR PF16533.5 VBB27045.1 - 1.2 9.1 8.9 0.24 11.4 3.3 2.7 1 1 0 2 2 2 0 STIM1 Orai1-activating region DAO PF01266.24 VBB27046.1 - 2.5e-54 185.2 0.0 1.3e-51 176.3 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 VBB27046.1 - 6.7e-06 24.9 0.0 0.0016 17.1 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 VBB27046.1 - 4.6e-05 23.6 0.1 9.8e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 VBB27046.1 - 0.00042 19.6 0.0 0.0007 18.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 VBB27046.1 - 0.00051 19.4 0.1 0.00087 18.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 VBB27046.1 - 0.00092 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 VBB27046.1 - 0.0089 16.6 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 VBB27046.1 - 0.015 14.6 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 VBB27046.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 VBB27046.1 - 0.1 11.6 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 VBB27046.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SIR2 PF02146.17 VBB27047.1 - 3.7e-49 167.0 0.0 8e-47 159.4 0.0 2.4 1 1 0 1 1 1 1 Sir2 family Ndc1_Nup PF09531.10 VBB27047.1 - 4.7e-22 78.4 27.0 3.9e-20 72.1 23.1 3.6 1 1 1 2 2 2 1 Nucleoporin protein Ndc1-Nup HTH_27 PF13463.6 VBB27047.1 - 0.22 12.1 0.8 3.2 8.3 0.7 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Glyco_transf_36 PF06165.11 VBB27048.1 - 0.026 14.0 0.2 0.031 13.7 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 36 Ribosomal_L5e PF17144.4 VBB27049.1 - 1e-75 253.2 8.7 1e-75 253.2 8.7 2.5 2 1 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 VBB27049.1 - 2.7e-31 108.4 7.7 2.7e-31 108.4 7.7 2.4 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 VBB27049.1 - 8.1e-05 22.9 0.9 0.0002 21.7 0.9 1.7 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta PA28_beta PF02252.18 VBB27049.1 - 0.003 17.2 0.5 0.0064 16.2 0.5 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit EGF PF00008.27 VBB27050.1 - 3e-99 324.7 305.1 2e-08 34.4 6.8 20.6 20 0 0 20 20 19 18 EGF-like domain hEGF PF12661.7 VBB27050.1 - 1.1e-66 219.4 244.7 2e-06 28.2 6.4 21.6 20 0 0 20 20 20 18 Human growth factor-like EGF Ank_2 PF12796.7 VBB27050.1 - 1.8e-41 140.6 13.9 2.8e-12 47.1 0.0 5.1 2 1 5 7 7 6 5 Ankyrin repeats (3 copies) EGF_CA PF07645.15 VBB27050.1 - 2.1e-26 91.9 322.8 2.8e-09 37.0 12.2 21.2 10 7 10 20 20 17 10 Calcium-binding EGF domain Notch PF00066.17 VBB27050.1 - 4.6e-25 87.8 54.3 4.2e-12 46.3 11.1 12.5 15 3 2 17 17 4 3 LNR domain Ank PF00023.30 VBB27050.1 - 1.5e-21 75.8 6.6 1.8e-06 28.1 0.4 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 VBB27050.1 - 1.9e-21 76.1 0.5 3.6e-08 33.8 0.3 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB27050.1 - 1.3e-20 71.3 3.9 0.0017 18.7 0.0 7.3 7 0 0 7 7 6 4 Ankyrin repeat Ank_5 PF13857.6 VBB27050.1 - 7.6e-20 70.7 1.9 5.3e-07 29.8 0.2 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) NODP PF07684.12 VBB27050.1 - 2.2e-14 53.4 0.0 2.2e-14 53.4 0.0 3.3 3 0 0 3 3 1 1 NOTCH protein EGF_2 PF07974.13 VBB27050.1 - 1.3e-10 41.5 352.4 0.0039 17.5 11.7 21.5 21 0 0 21 21 19 12 EGF-like domain NOD PF06816.13 VBB27050.1 - 8.4e-10 38.1 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NOTCH protein EGF_3 PF12947.7 VBB27050.1 - 9.4e-05 22.5 6.3 9.4e-05 22.5 6.3 21.1 16 3 5 21 21 18 9 EGF domain cEGF PF12662.7 VBB27050.1 - 0.0035 17.2 1.6 0.0035 17.2 1.6 21.6 19 3 1 20 20 20 7 Complement Clr-like EGF-like NDUF_B8 PF05821.11 VBB27050.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF19 PF01579.18 VBB27051.1 - 0.01 15.6 0.5 0.016 15.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) TMEM237 PF15383.6 VBB27052.1 - 0.049 12.7 2.1 0.18 10.8 2.1 2.0 1 0 0 1 1 1 0 Transmembrane protein 237 MRP-L46 PF11788.8 VBB27053.1 - 2.4e-08 34.7 1.8 8.5e-08 33.0 0.3 2.2 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 VBB27053.1 - 0.098 12.7 0.2 0.43 10.6 0.0 2.1 2 1 0 2 2 2 0 NUDIX domain KH_dom-like PF14714.6 VBB27053.1 - 0.1 13.0 0.0 5 7.5 0.0 2.5 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Cpn10 PF00166.21 VBB27053.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit SWIB PF02201.18 VBB27054.1 - 2.6e-24 84.9 0.2 7.8e-24 83.4 0.2 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain Methyltransf_23 PF13489.6 VBB27054.1 - 5.2e-11 42.7 0.1 1e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB27054.1 - 2.8e-10 40.8 0.0 7.2e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB27054.1 - 2.9e-10 40.8 0.0 7.5e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB27054.1 - 1.6e-08 35.0 0.0 4.8e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB27054.1 - 4.5e-07 29.8 0.0 9.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB27054.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DKCLD PF08068.12 VBB27054.1 - 0.057 13.5 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 DKCLD (NUC011) domain Methyltransf_2 PF00891.18 VBB27054.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF1018 PF06252.12 VBB27054.1 - 0.072 14.1 0.0 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF1682 PF07946.14 VBB27055.1 - 5.7e-81 272.2 5.2 7e-81 271.9 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) HEAT PF02985.22 VBB27056.1 - 5.6e-40 131.9 40.8 0.00069 19.7 0.0 22.3 22 0 0 22 22 21 9 HEAT repeat HEAT_2 PF13646.6 VBB27056.1 - 1.6e-25 89.3 19.6 9.5e-05 22.7 0.1 14.5 8 5 6 14 14 14 6 HEAT repeats HEAT_EZ PF13513.6 VBB27056.1 - 2.8e-19 69.2 33.6 0.041 14.4 0.0 16.8 15 4 3 18 18 18 6 HEAT-like repeat Vac14_Fab1_bd PF12755.7 VBB27056.1 - 1.3e-12 48.2 8.3 0.033 14.8 0.0 10.7 8 3 2 12 12 12 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 VBB27056.1 - 7.3e-11 42.1 29.1 0.0005 19.7 0.0 11.2 8 2 4 13 13 13 5 CLASP N terminal Cnd1 PF12717.7 VBB27056.1 - 3.2e-08 33.8 30.1 0.0019 18.3 0.0 11.9 10 3 3 14 14 13 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 VBB27056.1 - 1.6e-06 28.0 7.5 0.14 12.1 0.0 6.6 6 0 0 6 6 6 2 UME (NUC010) domain DUF3385 PF11865.8 VBB27056.1 - 1.6e-06 28.2 9.9 0.25 11.2 0.0 7.4 5 2 1 7 7 7 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 VBB27056.1 - 1.8e-06 26.8 44.9 0.0084 14.7 0.2 9.8 6 3 1 8 8 7 4 Adaptin N terminal region Dopey_N PF04118.14 VBB27056.1 - 1.4e-05 24.4 13.7 0.11 11.5 0.1 7.0 6 1 1 7 7 7 3 Dopey, N-terminal DUF937 PF06078.11 VBB27056.1 - 0.0049 17.5 0.0 0.34 11.5 0.0 4.0 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 VBB27056.1 - 0.0072 15.9 4.9 2.6 7.5 0.1 5.2 4 2 1 5 5 5 1 Tti2 family SCAPER_N PF16501.5 VBB27056.1 - 0.025 14.6 0.2 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum RNA_pol_Rpb1_5 PF04998.17 VBB27056.1 - 0.21 11.0 0.0 0.54 9.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 NUC173 PF08161.12 VBB27056.1 - 0.22 11.1 4.4 13 5.4 0.1 5.0 4 0 0 4 4 4 0 NUC173 domain Condensin2nSMC PF12422.8 VBB27056.1 - 0.35 11.0 7.0 3.5 7.8 0.0 5.8 7 0 0 7 7 6 0 Condensin II non structural maintenance of chromosomes subunit WD40 PF00400.32 VBB27058.1 - 1.2e-07 32.2 3.5 0.0023 18.7 0.4 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27058.1 - 0.016 15.5 0.0 23 5.4 0.0 3.6 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 VBB27058.1 - 0.041 12.5 0.0 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 BRCT PF00533.26 VBB27060.1 - 1.1e-09 38.6 1.2 0.00015 22.0 0.3 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 VBB27060.1 - 1.6e-08 34.4 0.3 1.1e-06 28.5 0.0 2.6 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 VBB27060.1 - 9e-06 26.0 0.0 0.026 14.9 0.0 3.2 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 VBB27060.1 - 0.025 14.6 0.1 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PAS_11 PF14598.6 VBB27061.1 - 0.031 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain Ribosomal_60s PF00428.19 VBB27063.1 - 1.9e-22 79.7 6.5 2.3e-22 79.4 6.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DMAP1_like PF17024.5 VBB27063.1 - 0.2 11.8 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative DMAP1-like RuvA_C PF07499.13 VBB27063.1 - 0.27 11.7 2.5 4 8.0 0.1 2.8 2 1 1 3 3 3 0 RuvA, C-terminal domain DUF4987 PF16377.5 VBB27064.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF1356 PF07092.12 VBB27066.1 - 1e-39 136.2 1.1 1.2e-39 136.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 VBB27066.1 - 0.0014 18.6 0.2 0.0026 17.7 0.2 1.4 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 VBB27066.1 - 0.0089 16.2 0.4 0.02 15.1 0.4 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5351) Exo84_C PF16528.5 VBB27067.1 - 5e-19 68.9 2.6 1.1e-15 58.0 0.0 3.3 2 1 1 3 3 3 2 Exocyst component 84 C-terminal Vps51 PF08700.11 VBB27067.1 - 5.1e-12 45.7 2.6 1.3e-11 44.4 2.6 1.7 1 0 0 1 1 1 1 Vps51/Vps67 PH PF00169.29 VBB27067.1 - 0.0013 19.2 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 PH domain COG2 PF06148.11 VBB27067.1 - 0.021 14.9 1.9 0.028 14.5 0.5 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 kleA_kleC PF17383.2 VBB27067.1 - 6.4 7.2 6.0 14 6.1 1.5 3.7 2 2 1 3 3 3 0 Uncharacterized KorC regulated protein A XPG_N PF00752.17 VBB27068.1 - 2.9e-32 111.1 0.0 8.4e-32 109.7 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 VBB27068.1 - 8.7e-30 102.9 0.1 2.1e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 VBB27068.1 - 4.7e-07 30.3 0.0 2.7e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Thioredoxin PF00085.20 VBB27069.1 - 1.2e-86 285.4 0.0 1.4e-21 76.4 0.0 6.2 6 0 0 6 6 6 5 Thioredoxin DnaJ PF00226.31 VBB27069.1 - 4.3e-20 71.6 2.1 1e-19 70.4 2.1 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.6 VBB27069.1 - 4.4e-14 52.8 0.0 7e-05 22.8 0.0 4.7 2 2 3 5 5 5 4 Thioredoxin-like domain OST3_OST6 PF04756.13 VBB27069.1 - 5.7e-14 52.2 0.0 4.1e-07 29.6 0.0 4.4 3 1 1 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 VBB27069.1 - 1.8e-13 50.6 5.3 0.044 14.1 0.0 6.8 6 2 1 7 7 7 5 Thioredoxin-like Thioredoxin_2 PF13098.6 VBB27069.1 - 1.3e-11 44.9 6.1 0.035 14.6 0.0 6.4 5 1 0 5 5 5 3 Thioredoxin-like domain AhpC-TSA PF00578.21 VBB27069.1 - 1.5e-08 34.6 1.5 0.04 13.8 0.0 4.7 5 0 0 5 5 5 3 AhpC/TSA family Redoxin PF08534.10 VBB27069.1 - 4.8e-08 32.8 0.3 0.019 14.6 0.0 4.2 4 0 0 4 4 4 2 Redoxin Thioredoxin_7 PF13899.6 VBB27069.1 - 1.4e-07 31.5 1.3 0.29 11.3 0.0 4.4 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_9 PF14595.6 VBB27069.1 - 2.7e-05 23.9 4.5 2.7 7.8 0.1 4.4 4 0 0 4 4 4 2 Thioredoxin TraF PF13728.6 VBB27069.1 - 0.00052 19.9 0.6 0.16 11.8 0.0 3.2 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 VBB27069.1 - 0.0016 18.5 1.2 0.08 13.0 0.0 3.8 5 0 0 5 5 4 1 Thioredoxin domain DUF3785 PF12653.7 VBB27069.1 - 0.025 14.7 0.1 1.4 9.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3785) TPR_2 PF07719.17 VBB27070.1 - 6.8e-21 72.6 16.0 0.00031 20.6 0.1 10.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 VBB27070.1 - 8.2e-16 57.4 17.9 0.11 13.4 0.0 9.2 6 3 4 10 10 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 VBB27070.1 - 3.7e-15 55.0 10.1 0.0039 16.9 0.1 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 VBB27070.1 - 8e-11 42.3 15.0 0.0013 19.1 0.1 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27070.1 - 1e-10 41.7 12.4 0.0018 18.5 0.0 5.5 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 VBB27070.1 - 1.1e-10 41.6 19.0 0.00074 19.8 3.1 7.4 5 3 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 VBB27070.1 - 1.9e-10 41.2 7.9 0.02 15.5 0.0 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27070.1 - 3.7e-09 36.1 17.8 0.039 14.2 0.1 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB27070.1 - 5e-08 32.6 8.1 1.1 9.2 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB27070.1 - 9.1e-08 32.0 8.1 1.9 9.0 0.0 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 VBB27070.1 - 5.9e-06 25.9 2.5 0.081 12.6 0.0 5.3 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 VBB27070.1 - 1.1e-05 25.1 12.7 0.12 12.5 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB27070.1 - 7.3e-05 22.8 11.3 0.21 11.8 0.2 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 VBB27070.1 - 0.25 11.8 3.4 7.6 7.0 0.0 4.2 4 2 1 5 5 5 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 VBB27070.1 - 1.5 9.6 9.8 13 6.7 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 VBB27070.1 - 3.6 8.0 7.9 19 5.7 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat SET PF00856.28 VBB27071.1 - 8.7e-20 71.8 0.1 8.7e-20 71.8 0.1 3.9 3 2 0 3 3 3 1 SET domain N-SET PF11764.8 VBB27071.1 - 2.9e-11 43.8 0.6 2.9e-11 43.8 0.6 4.7 4 1 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 VBB27071.1 - 1.1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Filament PF00038.21 VBB27072.1 - 1.9e-64 218.2 52.2 2.6e-63 214.5 52.2 2.1 1 1 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.19 VBB27072.1 - 1.5e-06 26.4 46.8 1.3e-05 23.3 7.4 2.4 1 1 1 2 2 2 2 Myosin tail DUF2353 PF09789.9 VBB27072.1 - 3.3e-05 23.4 15.7 3.3e-05 23.4 15.7 3.1 1 1 1 2 2 1 1 Uncharacterized coiled-coil protein (DUF2353) Uso1_p115_C PF04871.13 VBB27072.1 - 0.00024 21.4 9.7 0.00024 21.4 9.7 4.2 1 1 2 3 3 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 VBB27072.1 - 0.00037 21.0 51.7 0.39 11.2 2.9 5.6 2 1 3 5 5 5 3 Apg6 coiled-coil region Lebercilin PF15619.6 VBB27072.1 - 0.0015 18.2 45.2 0.15 11.7 22.1 2.5 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 VBB27072.1 - 0.0021 17.0 43.8 0.039 12.8 11.6 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein CENP-H PF05837.12 VBB27072.1 - 0.0049 17.2 6.8 0.0049 17.2 6.8 5.4 2 2 4 6 6 6 2 Centromere protein H (CENP-H) GAS PF13851.6 VBB27072.1 - 0.0053 16.1 46.1 0.071 12.4 8.8 3.9 1 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding SOGA PF11365.8 VBB27072.1 - 0.011 16.8 31.0 0.2 12.8 4.3 5.4 1 1 4 5 5 5 0 Protein SOGA TPR_MLP1_2 PF07926.12 VBB27072.1 - 0.014 15.5 42.6 0.022 14.8 1.1 5.2 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Ribosomal_L23 PF00276.20 VBB27072.1 - 0.031 14.7 0.0 6.9 7.1 0.0 2.9 2 0 0 2 2 2 0 Ribosomal protein L23 Bacillus_HBL PF05791.11 VBB27072.1 - 0.031 14.1 21.8 0.034 14.0 1.9 3.5 2 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 VBB27072.1 - 0.21 11.8 51.1 0.86 9.8 24.8 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 VBB27072.1 - 0.22 11.6 48.2 0.34 11.0 4.9 5.4 3 2 2 5 5 5 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 VBB27072.1 - 0.3 11.1 31.8 1.3 9.1 0.5 5.8 4 2 2 6 6 6 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 VBB27072.1 - 0.33 11.6 33.9 0.42 11.3 5.7 5.7 1 1 3 5 5 5 0 Initiation control protein YabA MAD PF05557.13 VBB27072.1 - 0.35 9.2 47.8 0.39 9.0 31.2 2.7 1 1 1 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 VBB27072.1 - 0.59 10.6 42.1 2 8.8 5.3 4.0 1 1 2 3 3 3 0 Fez1 UPF0242 PF06785.11 VBB27072.1 - 0.59 10.2 47.7 0.32 11.1 13.3 3.8 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus FPP PF05911.11 VBB27072.1 - 0.99 7.5 35.6 0.77 7.9 17.0 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil UPF0184 PF03670.13 VBB27072.1 - 1.2 9.6 8.0 2.7 8.4 0.3 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) WD40_alt PF14077.6 VBB27072.1 - 1.3 8.9 4.4 10 6.1 1.6 3.2 2 1 0 2 2 2 0 Alternative WD40 repeat motif DUF4407 PF14362.6 VBB27072.1 - 1.3 8.3 36.6 0.39 10.0 14.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 VBB27072.1 - 2.1 8.2 43.4 0.86 9.4 13.9 3.5 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH PEARLI-4 PF05278.12 VBB27072.1 - 2.3 7.7 22.6 0.024 14.2 1.3 3.6 4 0 0 4 4 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF948 PF06103.11 VBB27072.1 - 4.9 7.5 12.5 2.5 8.4 0.9 4.0 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 VBB27072.1 - 5.6 7.0 46.7 11 6.1 19.9 4.3 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 VBB27072.1 - 5.6 6.4 49.7 0.16 11.5 26.8 3.0 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain DUF4988 PF16378.5 VBB27072.1 - 5.9 6.5 8.7 21 4.7 0.8 3.8 3 0 0 3 3 3 0 Domain of unknown function DUF3584 PF12128.8 VBB27072.1 - 9.9 3.5 46.1 1.6 6.2 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Rad60-SLD PF11976.8 VBB27073.1 - 3.7e-17 61.9 0.1 4.3e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 VBB27073.1 - 3.4e-13 49.1 0.1 4.2e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family UIM PF02809.20 VBB27074.1 - 4.8e-06 26.1 13.3 0.02 14.8 0.1 4.8 4 1 1 5 5 5 3 Ubiquitin interaction motif SpoVAC_SpoVAEB PF03862.13 VBB27075.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein NOA36 PF06524.12 VBB27076.1 - 1.4e-69 234.8 47.2 1.4e-69 234.8 47.2 4.3 1 1 2 3 3 3 1 NOA36 protein Actin PF00022.19 VBB27077.1 - 3.1e-42 144.6 0.0 1.2e-41 142.7 0.0 1.8 1 1 0 1 1 1 1 Actin Fumble PF03630.14 VBB27078.1 - 1.2e-106 356.7 0.0 1.4e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Fumble Acyltransferase PF01553.21 VBB27079.1 - 9.8e-19 67.3 0.0 1.7e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase_Tyr PF07714.17 VBB27080.1 - 5.4e-57 193.0 0.0 7.7e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB27080.1 - 2.3e-54 184.6 0.0 3.5e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 VBB27080.1 - 5.8e-18 64.7 0.1 1.1e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 VBB27080.1 - 1.6e-12 47.1 8.5 3.2e-12 46.1 8.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 VBB27080.1 - 4e-06 26.3 0.0 6.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 VBB27080.1 - 0.00019 21.6 3.9 0.0005 20.3 3.9 1.7 1 0 0 1 1 1 1 C1 domain Pkinase_fungal PF17667.1 VBB27080.1 - 0.00027 19.8 0.0 0.00043 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB27080.1 - 0.0087 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB27080.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING-like PF08746.11 VBB27080.1 - 0.24 11.8 7.9 0.63 10.4 7.9 1.7 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 VBB27080.1 - 3.9 7.7 8.9 0.93 9.7 4.8 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger Ribophorin_II PF05817.14 VBB27081.1 - 2e-157 525.5 4.8 2.4e-157 525.3 4.8 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Laminin_G_3 PF13385.6 VBB27082.1 - 3.6e-10 40.2 0.0 7.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Notch PF00066.17 VBB27082.1 - 6.8e-08 32.8 20.4 0.00055 20.3 13.0 2.8 1 1 1 2 2 2 2 LNR domain Peptidase_M43 PF05572.13 VBB27082.1 - 8.6e-07 29.0 0.1 8.6e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 VBB27082.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Matrixin Birna_VP3 PF01767.16 VBB27083.1 - 0.014 15.5 0.9 0.017 15.2 0.9 1.2 1 0 0 1 1 1 0 Birnavirus VP3 protein DUF2250 PF10007.9 VBB27083.1 - 0.016 15.3 0.9 0.94 9.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Ank_2 PF12796.7 VBB27084.1 - 3.8e-22 78.7 0.0 3.2e-16 59.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB27084.1 - 3.6e-21 75.2 1.9 4.8e-08 33.4 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB27084.1 - 1.4e-17 61.9 0.0 0.00056 20.2 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 VBB27084.1 - 7.1e-17 61.0 2.3 6.4e-06 26.4 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 VBB27084.1 - 1.3e-10 41.3 2.8 0.0011 19.3 0.2 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Sushi PF00084.20 VBB27084.1 - 2.3e-10 40.9 34.3 8.7e-05 23.1 1.5 5.7 5 1 1 6 6 6 4 Sushi repeat (SCR repeat) DUF4215 PF13948.6 VBB27084.1 - 0.0046 17.3 1.6 0.0046 17.3 1.6 5.6 6 0 0 6 6 6 1 Domain of unknown function (DUF4215) DHHC PF01529.20 VBB27085.1 - 5.3e-27 94.6 13.7 5.3e-27 94.6 13.7 2.5 1 1 2 3 3 3 1 DHHC palmitoyltransferase Peptidase_U4 PF03419.13 VBB27085.1 - 9.1 5.5 15.2 2 7.6 8.0 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Ank_2 PF12796.7 VBB27086.1 - 6.5e-34 116.4 18.1 6.7e-10 39.4 0.1 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 VBB27086.1 - 5.8e-18 64.5 12.2 7.7e-06 26.1 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 VBB27086.1 - 7e-18 64.8 4.0 8.6e-06 26.2 0.0 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB27086.1 - 4.5e-16 58.7 8.9 1.3e-09 38.2 0.2 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Patatin PF01734.22 VBB27086.1 - 5.2e-15 56.2 0.7 8.1e-14 52.3 0.7 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_3 PF13606.6 VBB27086.1 - 1e-13 50.1 4.8 0.0064 16.9 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Fumble PF03630.14 VBB27086.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Fumble DUF719 PF05334.13 VBB27087.1 - 1.3e-17 64.6 0.8 5.5e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF719) DREV PF05219.12 VBB27088.1 - 1.5e-67 227.5 0.3 1.7e-67 227.3 0.3 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 VBB27088.1 - 1e-05 25.4 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 VBB27088.1 - 0.0094 15.6 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF3231 PF11553.8 VBB27088.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Methyltransf_11 PF08241.12 VBB27088.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TLD PF07534.16 VBB27089.1 - 3e-21 76.1 0.1 6.2e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 TLD PQ-loop PF04193.14 VBB27089.1 - 9.4e-17 60.5 12.7 2.1e-08 33.8 4.9 2.6 2 0 0 2 2 2 2 PQ loop repeat RabGAP-TBC PF00566.18 VBB27089.1 - 5.2e-15 55.7 0.6 1.6e-14 54.1 0.6 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Tim29 PF10171.9 VBB27089.1 - 5e-08 32.6 0.0 1.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 UCH PF00443.29 VBB27090.1 - 1.5e-13 50.8 0.0 3.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB27090.1 - 0.00023 20.9 0.2 0.00067 19.3 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nyv1_N PF09426.10 VBB27090.1 - 0.052 13.6 1.7 0.08 13.0 0.3 2.0 2 0 0 2 2 2 0 Vacuolar R-SNARE Nyv1 N terminal Nbl1_Borealin_N PF10444.9 VBB27090.1 - 0.1 12.2 1.1 0.27 10.9 1.1 1.7 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal TPT PF03151.16 VBB27091.1 - 1e-09 38.2 12.9 1.2e-09 38.0 12.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DENN PF02141.21 VBB27092.1 - 3.2e-43 147.9 3.9 5.9e-43 147.0 3.9 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.19 VBB27092.1 - 8.1e-28 97.1 1.9 1e-13 51.4 0.1 3.6 3 0 0 3 3 3 2 RUN domain dDENN PF03455.19 VBB27092.1 - 1.2e-16 60.4 1.7 3.8e-16 58.8 1.7 2.0 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.23 VBB27092.1 - 1.2e-09 38.8 0.0 2.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain uDENN PF03456.18 VBB27092.1 - 1e-08 35.8 0.0 2.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 uDENN domain BTB PF00651.31 VBB27094.1 - 6.1e-24 84.4 0.0 1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 VBB27094.1 - 0.0013 18.8 0.0 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Acyl-CoA_dh_1 PF00441.24 VBB27095.1 - 6.3e-37 127.1 0.7 6.3e-37 127.1 0.7 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 VBB27095.1 - 1.1e-24 87.2 0.0 2.3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 VBB27095.1 - 1.5e-24 86.0 0.3 2.6e-24 85.2 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 VBB27095.1 - 8.5e-13 48.7 0.0 2.9e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Vps23_core PF09454.10 VBB27095.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Vps23 core domain MaoC_dehydratas PF01575.19 VBB27096.1 - 2.8e-31 107.6 0.0 1.4e-30 105.4 0.0 2.1 3 0 0 3 3 3 1 MaoC like domain MaoC_dehydrat_N PF13452.6 VBB27096.1 - 1.5e-08 34.9 0.0 2.7e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase N2227 PF07942.12 VBB27097.1 - 5.9e-93 311.0 0.0 1e-92 310.2 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein Zn_ribbon_17 PF17120.5 VBB27097.1 - 2e-05 24.1 13.2 6.4e-05 22.5 13.2 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 VBB27097.1 - 0.00085 19.5 3.5 0.0033 17.6 3.5 2.1 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 VBB27097.1 - 0.0012 19.7 4.1 0.7 10.9 1.3 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat L51_S25_CI-B8 PF05047.16 VBB27097.1 - 0.0014 18.5 0.2 0.0034 17.3 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Med10 PF09748.9 VBB27098.1 - 3.5e-30 104.5 1.3 5.5e-30 103.8 1.3 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex 5_nucleotid PF05761.14 VBB27099.1 - 6.4e-112 374.8 10.3 6.4e-69 233.0 0.0 3.5 1 1 2 3 3 3 3 5' nucleotidase family MRP-L47 PF06984.13 VBB27099.1 - 1.8e-30 104.9 0.4 5.4e-30 103.4 0.4 1.9 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) TPR_19 PF14559.6 VBB27099.1 - 5.7e-12 46.0 6.7 0.0012 19.3 0.6 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27099.1 - 1.2e-06 28.2 20.5 0.46 10.7 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB27099.1 - 2.3e-06 27.2 1.4 0.18 11.9 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27099.1 - 8.2e-06 26.0 29.0 0.041 14.1 0.5 6.4 5 2 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 VBB27099.1 - 1.4e-05 25.5 2.3 18 6.5 0.0 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 VBB27099.1 - 1.8e-05 24.7 2.7 0.11 12.8 0.1 5.1 6 0 0 6 6 5 1 PPR repeat TPR_12 PF13424.6 VBB27099.1 - 8.5e-05 22.8 13.7 1.2 9.5 0.0 6.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB27099.1 - 8.8e-05 22.9 5.5 1.9 9.3 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB27099.1 - 0.00017 22.2 0.7 5.6 7.7 0.0 5.2 5 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27099.1 - 0.00021 21.2 14.6 1.9 8.9 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR_2 PF13041.6 VBB27099.1 - 0.00041 20.5 2.1 0.45 10.8 0.1 4.1 4 0 0 4 4 4 1 PPR repeat family TPR_1 PF00515.28 VBB27099.1 - 0.019 14.8 17.9 0.41 10.5 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3024 PF11225.8 VBB27099.1 - 0.025 14.8 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) TPR_9 PF13371.6 VBB27099.1 - 0.029 14.5 0.1 0.34 11.1 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB27099.1 - 0.095 12.8 4.7 3.5 7.8 2.4 3.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat EF_assoc_2 PF08356.12 VBB27099.1 - 0.11 12.5 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 EF hand associated TPR_4 PF07721.14 VBB27099.1 - 0.12 13.1 0.0 32 5.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB27099.1 - 1.8 9.1 5.6 9.2 6.9 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF236 PF03057.14 VBB27100.1 - 2.3e-19 69.0 0.8 6.8e-13 48.3 0.2 2.3 2 0 0 2 2 2 2 DUF236 repeat Presenilin PF01080.17 VBB27100.1 - 0.2 10.4 14.6 0.2 10.4 14.6 1.1 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 VBB27100.1 - 0.99 8.4 16.0 1.1 8.3 16.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Red1 PF07964.11 VBB27100.1 - 1.9 6.6 27.6 2 6.6 27.6 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Dsh_C PF12316.8 VBB27100.1 - 2.1 8.7 8.9 2.8 8.3 8.9 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SLC12 PF03522.15 VBB27100.1 - 2.2 7.2 14.4 2.3 7.1 14.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Trypan_PARP PF05887.11 VBB27100.1 - 3.8 7.5 16.0 5 7.1 16.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.22 VBB27100.1 - 4.7 6.3 14.7 5.9 6.0 14.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 VBB27100.1 - 6.3 5.4 14.7 7.8 5.1 14.7 1.1 1 0 0 1 1 1 0 Raftlin Topoisom_bac PF01131.20 VBB27101.1 - 3.6e-108 362.2 0.0 5.6e-108 361.6 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 VBB27101.1 - 2.1e-16 60.0 0.0 5.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zinc_ribbon_4 PF13717.6 VBB27101.1 - 0.0041 17.0 8.5 0.79 9.7 1.1 3.9 3 0 0 3 3 3 2 zinc-ribbon domain CAS_C PF12026.8 VBB27101.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Crk-Associated Substrate C-terminal domain Ribosomal_S27 PF01599.19 VBB27101.1 - 0.31 11.2 0.0 0.31 11.2 0.0 4.0 5 0 0 5 5 5 0 Ribosomal protein S27a PAS_3 PF08447.12 VBB27102.1 - 3.2e-06 27.3 0.4 8.5e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 VBB27102.1 - 3.9e-05 23.7 0.0 8.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 VBB27102.1 - 0.0023 17.9 0.0 0.0076 16.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold HLH PF00010.26 VBB27102.1 - 0.025 14.5 0.9 0.08 12.9 0.9 1.9 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 VBB27102.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 PAS domain Ribosomal_L6e PF01159.19 VBB27104.1 - 1.6e-34 118.8 0.1 3e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 VBB27104.1 - 2.1e-10 40.7 5.6 2.1e-10 40.7 5.6 2.8 3 1 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Ribonuclease_3 PF00636.26 VBB27105.1 - 1.8e-59 198.9 0.0 9.9e-35 119.3 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.22 VBB27105.1 - 3.2e-36 124.1 0.0 8.2e-36 122.8 0.0 1.7 1 0 0 1 1 1 1 PAZ domain MRP-L51 PF10244.9 VBB27105.1 - 1.1e-31 108.9 1.5 2.9e-31 107.5 1.5 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit Ribonucleas_3_3 PF14622.6 VBB27105.1 - 6.3e-26 91.0 0.1 1.2e-16 61.0 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 VBB27105.1 - 7e-25 87.0 0.1 2.1e-24 85.5 0.1 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 VBB27105.1 - 9.7e-15 54.9 0.1 7.4e-14 52.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB27105.1 - 1.4e-12 47.9 0.0 9.2e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB27105.1 - 2e-10 40.7 0.0 3.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 VBB27105.1 - 0.054 14.2 0.0 3.7 8.3 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif APOBEC3 PF18771.1 VBB27105.1 - 0.082 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 APOBEC3 C6_DPF PF10170.9 VBB27106.1 - 1.5e-18 66.9 0.4 2e-18 66.5 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich domain RGS PF00615.19 VBB27107.1 - 2.4e-34 118.1 5.5 1.4e-18 67.2 0.2 3.1 3 0 0 3 3 3 2 Regulator of G protein signaling domain EGF_3 PF12947.7 VBB27108.1 - 4.8e-74 244.2 375.8 3.2e-09 36.8 5.2 26.2 27 0 0 27 27 27 17 EGF domain EGF_CA PF07645.15 VBB27108.1 - 4e-50 167.8 139.4 1.4e-10 41.2 5.4 29.0 27 2 2 29 29 29 12 Calcium-binding EGF domain cEGF PF12662.7 VBB27108.1 - 5.4e-31 106.2 250.0 3.6e-06 26.8 7.4 26.7 26 2 0 26 26 26 20 Complement Clr-like EGF-like EGF PF00008.27 VBB27108.1 - 3.2e-08 33.7 329.4 0.00017 21.8 5.4 26.7 26 1 0 26 26 26 14 EGF-like domain EGF_MSP1_1 PF12946.7 VBB27108.1 - 1.1e-05 25.4 19.6 4.4e-05 23.4 6.0 24.7 25 0 0 25 25 25 10 MSP1 EGF domain 1 hEGF PF12661.7 VBB27108.1 - 0.0083 16.7 3.2 0.0083 16.7 3.2 27.0 29 0 0 29 29 29 11 Human growth factor-like EGF CAP_N PF01213.19 VBB27109.1 - 1.4 8.3 5.7 1.9 7.9 5.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2200 PF09966.9 VBB27112.1 - 0.033 14.3 0.2 0.056 13.6 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) MOZ_SAS PF01853.18 VBB27113.1 - 7.2e-76 253.8 0.2 1.2e-75 253.1 0.2 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 VBB27113.1 - 2.5e-20 71.8 1.6 2.5e-20 71.8 1.6 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 VBB27113.1 - 0.0017 18.7 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RepL PF05732.11 VBB27113.1 - 0.023 14.1 0.3 0.061 12.8 0.3 1.7 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) DUF4684 PF15736.5 VBB27113.1 - 0.99 8.0 5.8 0.29 9.8 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4684) SH2 PF00017.24 VBB27114.1 - 4.1e-14 52.4 0.0 8.5e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Pro_isomerase PF00160.21 VBB27115.1 - 1.1e-52 178.5 0.0 1.2e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ELO PF01151.18 VBB27116.1 - 2.8e-40 138.4 9.7 3.4e-40 138.2 9.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Amidohydro_1 PF01979.20 VBB27117.1 - 1.4e-11 44.3 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 VBB27117.1 - 9.3e-07 28.7 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family HPS3_N PF14761.6 VBB27117.1 - 0.0033 17.0 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 DDRGK PF09756.9 VBB27117.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain C6 PF01681.17 VBB27118.1 - 0.01 16.4 1.2 0.02 15.4 1.2 1.6 1 1 0 1 1 1 1 C6 domain Lectin_C PF00059.21 VBB27119.1 - 8e-11 42.6 0.1 8e-11 42.6 0.1 2.7 4 0 0 4 4 4 1 Lectin C-type domain ShK PF01549.24 VBB27119.1 - 6.5e-08 33.0 15.2 8.2e-05 23.1 3.1 4.8 5 0 0 5 5 5 3 ShK domain-like Sof1 PF04158.14 VBB27120.1 - 6.6e-29 100.0 3.6 1e-28 99.4 3.6 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 VBB27120.1 - 2.7e-12 47.0 14.0 9.8e-06 26.2 0.0 6.5 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27120.1 - 0.029 14.6 0.0 2.4 8.5 0.0 3.3 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3338 PF11819.8 VBB27120.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Pkinase PF00069.25 VBB27121.1 - 6.5e-16 58.5 0.0 7.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27121.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB27121.1 - 0.003 16.4 0.0 0.004 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Cpn60_TCP1 PF00118.24 VBB27122.1 - 7.9e-131 437.0 11.3 7.5e-75 252.4 3.4 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Sec63 PF02889.16 VBB27123.1 - 5.4e-116 386.2 3.5 2.8e-59 200.4 0.5 3.0 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 VBB27123.1 - 6.6e-53 179.1 0.9 2.4e-26 92.6 0.8 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 VBB27123.1 - 9.2e-25 87.6 0.1 4.3e-11 43.1 0.1 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 VBB27123.1 - 4.4e-18 65.6 0.0 1.1e-07 32.2 0.0 3.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 VBB27123.1 - 2.7e-08 34.2 1.3 0.0011 19.2 0.1 3.9 3 1 0 3 3 3 2 AAA domain Helicase_PWI PF18149.1 VBB27123.1 - 1.7e-05 25.0 0.1 6.9e-05 23.0 0.1 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 VBB27123.1 - 0.0042 16.2 0.0 2.2 7.3 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein CAAP1 PF15335.6 VBB27123.1 - 0.0097 16.4 0.3 0.11 13.0 0.1 3.0 2 0 0 2 2 2 1 Caspase activity and apoptosis inhibitor 1 PhoH PF02562.16 VBB27123.1 - 0.031 13.7 0.0 8.7 5.7 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 VBB27123.1 - 0.036 13.8 3.4 0.46 10.2 0.0 4.3 6 0 0 6 6 6 0 IstB-like ATP binding protein AAA_23 PF13476.6 VBB27123.1 - 1 9.8 9.2 30 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 VBB27123.1 - 1 9.1 7.8 10 5.8 0.0 3.5 3 1 0 4 4 4 0 AAA domain Transketolase_N PF00456.21 VBB27124.1 - 2.1e-36 125.6 0.1 3.6e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 VBB27124.1 - 2.4e-35 121.8 0.0 4.8e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 VBB27124.1 - 3.1e-28 98.1 0.0 6.8e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 VBB27124.1 - 0.00034 19.7 0.0 0.00059 18.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 VBB27124.1 - 0.0086 15.9 0.2 0.022 14.5 0.2 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 VBB27124.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II CHASE2 PF05226.11 VBB27124.1 - 0.16 11.7 0.0 3.8 7.1 0.0 2.4 2 1 0 2 2 2 0 CHASE2 domain ProRS-C_1 PF09180.11 VBB27125.1 - 3.9e-21 75.0 0.3 7.1e-21 74.2 0.3 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 VBB27125.1 - 2.9e-15 56.2 0.1 6.3e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain PilJ PF13675.6 VBB27125.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3829 PF12889.7 VBB27125.1 - 0.08 12.4 0.3 0.08 12.4 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF848 PF05852.11 VBB27125.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Glyco_transf_92 PF01697.27 VBB27126.1 - 9.8e-25 87.7 3.1 3.2e-22 79.4 0.7 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 92 DUF3989 PF13150.6 VBB27126.1 - 0.039 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF5093 PF17011.5 VBB27126.1 - 0.11 12.7 0.4 0.34 11.2 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5093) Ion_trans_2 PF07885.16 VBB27127.1 - 3e-37 126.4 15.7 2.8e-19 68.8 3.1 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB27127.1 - 1.3e-06 27.8 8.6 0.005 16.1 1.4 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 VBB27127.1 - 0.018 14.8 0.4 0.05 13.4 0.0 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF4101 PF13355.6 VBB27127.1 - 0.07 13.6 2.8 0.84 10.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) TraL PF07178.11 VBB27127.1 - 0.31 11.5 1.3 2.7 8.5 0.4 2.8 2 1 1 3 3 3 0 TraL protein PAS_3 PF08447.12 VBB27129.1 - 4.1e-11 43.0 0.0 1.1e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold HLH PF00010.26 VBB27129.1 - 3.4e-10 39.7 2.1 8e-10 38.5 2.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_11 PF14598.6 VBB27129.1 - 4.3e-07 30.0 0.0 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 VBB27129.1 - 6e-07 29.5 0.0 0.0045 17.0 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 VBB27129.1 - 0.0002 21.5 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain CAML PF14963.6 VBB27130.1 - 0.07 13.2 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand RabGAP-TBC PF00566.18 VBB27131.1 - 1.5e-28 99.9 12.4 2.1e-15 56.9 5.0 3.0 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Josephin PF02099.17 VBB27132.1 - 2.5e-24 86.2 1.5 6.8e-23 81.6 1.5 2.3 1 1 0 1 1 1 1 Josephin MRP-S33 PF08293.11 VBB27132.1 - 1.9e-13 50.5 0.1 4.8e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit S27 WD40 PF00400.32 VBB27133.1 - 1.4e-09 38.4 5.4 0.0068 17.2 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27133.1 - 1.1e-05 25.6 0.9 1.2 9.4 0.0 4.2 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_alt PF14077.6 VBB27133.1 - 0.0041 17.0 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Alternative WD40 repeat motif DUF1513 PF07433.11 VBB27133.1 - 0.024 13.7 0.2 0.97 8.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Macoilin PF09726.9 VBB27134.1 - 3.5e-109 366.3 48.7 2.5e-69 234.6 29.7 2.3 2 1 0 2 2 2 2 Macoilin family I-set PF07679.16 VBB27135.1 - 5.2e-13 48.9 0.1 2.5e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB27135.1 - 6e-12 46.0 0.8 9.9e-11 42.1 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 VBB27135.1 - 1.2e-06 28.8 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB27135.1 - 0.00036 20.7 0.1 0.0015 18.7 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 VBB27135.1 - 0.0011 19.1 0.2 0.0011 19.1 0.2 1.9 2 0 0 2 2 2 1 Immunoglobulin domain DUF2140 PF09911.9 VBB27135.1 - 0.0054 16.3 1.3 0.0087 15.6 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) TMIE PF16038.5 VBB27135.1 - 0.015 15.1 0.8 0.029 14.2 0.8 1.5 1 0 0 1 1 1 0 TMIE protein DUF1282 PF06930.12 VBB27135.1 - 0.044 13.6 0.9 0.066 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) OPA3 PF07047.12 VBB27135.1 - 0.076 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF4381 PF14316.6 VBB27135.1 - 0.078 13.2 2.2 0.26 11.5 2.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Sigma_reg_N PF13800.6 VBB27135.1 - 0.14 12.5 1.2 0.26 11.6 1.2 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf-C2H2_2 PF12756.7 VBB27136.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 VBB27136.1 - 0.22 12.1 1.1 0.55 10.8 1.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type tRNA-synt_1 PF00133.22 VBB27137.1 - 1.8e-135 452.6 0.1 2.5e-135 452.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 VBB27137.1 - 8.8e-16 58.2 0.4 4.3e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 VBB27137.1 - 3.3e-14 52.4 0.0 5.9e-09 35.1 0.0 3.7 4 0 0 4 4 4 3 tRNA synthetases class I (M) Sec8_exocyst PF04048.14 VBB27137.1 - 1.8e-09 37.7 0.1 5.9e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 VBB27137.1 - 0.014 14.7 4.9 0.0075 15.6 1.9 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex tRNA-synt_1f PF01921.18 VBB27137.1 - 0.062 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) MADF_DNA_bdg PF10545.9 VBB27138.1 - 1.6e-12 47.5 0.2 3.2e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB27138.1 - 0.0015 18.9 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RtcB PF01139.17 VBB27139.1 - 4.8e-55 187.4 0.0 5.8e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ALMS_motif PF15309.6 VBB27140.1 - 0.28 11.7 11.2 0.086 13.3 6.0 2.4 2 0 0 2 2 2 0 ALMS motif Pkinase PF00069.25 VBB27141.1 - 1.2e-56 192.0 0.0 2.2e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27141.1 - 3.5e-23 82.2 0.0 9.2e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 VBB27141.1 - 9e-20 70.6 6.0 0.00099 19.9 0.1 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27141.1 - 1e-07 32.1 0.1 2.4 8.5 0.0 5.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain APH PF01636.23 VBB27141.1 - 0.063 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MutS_V PF00488.21 VBB27142.1 - 2e-53 181.2 0.5 1.4e-52 178.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 VBB27142.1 - 4.5e-27 95.5 5.4 4.9e-27 95.4 3.6 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 VBB27142.1 - 8.8e-11 42.2 0.2 2.9e-10 40.5 0.2 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 VBB27142.1 - 4.6e-07 30.1 0.0 1.6e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 VBB27142.1 - 0.0085 16.6 2.4 0.016 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 VBB27142.1 - 0.021 14.4 0.0 0.07 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 VBB27143.1 - 4.4e-54 183.6 2.2 5.2e-54 183.4 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27143.1 - 1.3e-27 96.7 0.0 3.8e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase TMF_DNA_bd PF12329.8 VBB27143.1 - 0.00043 20.2 13.2 0.00043 20.2 13.2 7.2 2 1 5 7 7 7 1 TATA element modulatory factor 1 DNA binding Kdo PF06293.14 VBB27143.1 - 0.00047 19.6 0.0 0.00047 19.6 0.0 2.7 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0176_N PF17773.1 VBB27143.1 - 0.16 12.3 1.7 0.43 11.0 0.1 2.6 3 0 0 3 3 3 0 UPF0176 acylphosphatase like domain APH PF01636.23 VBB27143.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family HTH_37 PF13744.6 VBB27143.1 - 3.5 7.6 8.2 1.1 9.3 2.5 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Baculo_PEP_C PF04513.12 VBB27143.1 - 7.3 6.6 22.3 0.75 9.8 4.3 3.7 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 VBB27144.1 - 1.8e-11 44.3 6.4 1.8e-11 44.3 6.4 3.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 VBB27144.1 - 0.0003 20.8 8.5 0.0003 20.8 8.5 2.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-BED PF02892.15 VBB27144.1 - 0.0019 18.2 12.4 1.6 8.8 0.0 5.1 5 0 0 5 5 5 2 BED zinc finger PLCC PF14466.6 VBB27144.1 - 0.011 15.9 0.2 0.048 13.8 0.0 2.2 3 0 0 3 3 3 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein zf-C2H2_3rep PF18868.1 VBB27144.1 - 0.025 15.3 0.1 0.21 12.3 0.1 2.7 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Siah-Interact_N PF09032.11 VBB27144.1 - 0.092 13.1 1.3 3.6 8.0 0.7 3.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal zf-Di19 PF05605.12 VBB27144.1 - 0.12 12.7 0.2 0.12 12.7 0.2 4.8 5 1 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding RepB_primase PF16793.5 VBB27144.1 - 2.7 8.1 6.6 1.9 8.5 0.2 2.9 3 0 0 3 3 3 0 RepB DNA-primase from phage plasmid Fzo_mitofusin PF04799.13 VBB27144.1 - 4.9 6.7 6.9 1.2 8.7 0.5 2.4 2 0 0 2 2 2 0 fzo-like conserved region zf-C2H2 PF00096.26 VBB27145.1 - 4.6e-09 36.2 40.9 0.0023 18.3 4.5 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB27145.1 - 5.7e-07 29.7 0.7 5.7e-07 29.7 0.7 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 VBB27145.1 - 0.00016 21.4 4.7 0.00016 21.4 4.7 3.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 VBB27145.1 - 0.00046 20.8 41.0 0.026 15.4 3.1 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 VBB27145.1 - 0.024 15.0 1.7 0.024 15.0 1.7 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FHIPEP PF00771.20 VBB27145.1 - 0.38 9.2 2.6 0.62 8.5 2.6 1.2 1 0 0 1 1 1 0 FHIPEP family DNApol_Exo PF18136.1 VBB27145.1 - 0.9 8.6 5.1 0.21 10.7 0.3 2.2 3 0 0 3 3 3 0 DNA mitochondrial polymerase exonuclease domain zf-FCS PF06467.14 VBB27145.1 - 6.6 6.8 13.6 5.1 7.1 5.0 3.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SKIP_SNW PF02731.15 VBB27146.1 - 1.2e-71 239.6 5.2 1.2e-71 239.6 5.2 1.7 2 0 0 2 2 2 1 SKIP/SNW domain RMI1_N PF08585.12 VBB27147.1 - 2.6e-37 128.7 1.8 2.7e-37 128.6 0.1 1.9 2 0 0 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 VBB27147.1 - 4.1e-09 36.4 0.0 1.2e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Recq-mediated genome instability protein 1, C-terminal OB-fold L51_S25_CI-B8 PF05047.16 VBB27149.1 - 2.9e-13 49.5 0.1 3.5e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DB PF01682.19 VBB27151.1 - 6.5e-05 23.2 3.1 0.0004 20.6 1.6 2.3 2 1 0 2 2 2 1 DB module Plectin PF00681.20 VBB27152.1 - 9e-83 271.9 5.7 0.057 13.3 0.0 35.2 32 6 7 39 39 39 21 Plectin repeat Spectrin PF00435.21 VBB27152.1 - 6.9e-23 81.1 50.5 3.9e-06 27.3 1.5 10.1 8 1 0 9 9 9 7 Spectrin repeat CH PF00307.31 VBB27152.1 - 2.3e-22 79.3 0.2 3.6e-21 75.4 0.0 3.2 3 0 0 3 3 3 1 Calponin homology (CH) domain SH3_10 PF17902.1 VBB27152.1 - 4.4e-19 68.3 0.0 1.4e-18 66.7 0.0 2.0 1 0 0 1 1 1 1 SH3 domain CAMSAP_CH PF11971.8 VBB27152.1 - 4.4e-06 26.4 0.0 2e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 CAMSAP CH domain Spectrin_like PF18373.1 VBB27152.1 - 0.0054 16.8 11.8 0.046 13.8 0.0 4.7 4 1 0 4 4 4 1 Spectrin like domain MEKHLA PF08670.11 VBB27152.1 - 0.12 12.3 0.2 96 2.9 0.0 5.0 6 0 0 6 6 6 0 MEKHLA domain HSBP1 PF06825.12 VBB27152.1 - 5.7 6.9 8.6 20 5.1 0.1 4.7 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Spectrin PF00435.21 VBB27153.1 - 1.5e-81 269.7 252.2 2.3e-10 40.9 0.9 30.3 23 4 8 32 32 32 20 Spectrin repeat GAS2 PF02187.17 VBB27153.1 - 4.7e-30 103.5 1.1 1.5e-29 101.9 1.1 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_7 PF13499.6 VBB27153.1 - 0.0021 18.5 0.1 0.14 12.6 0.0 4.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB27153.1 - 0.048 13.6 0.2 21 5.4 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain TPR_14 PF13428.6 VBB27153.1 - 0.079 13.8 0.5 1.9 9.5 0.1 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1079 PF06435.11 VBB27153.1 - 0.096 12.9 0.1 14 6.1 0.0 4.7 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) DUF4872 PF16169.5 VBB27153.1 - 4.2 7.1 7.5 2.7 7.7 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4872) Peptidase_M1 PF01433.20 VBB27155.1 - 1e-79 267.1 1.6 2.6e-79 265.8 1.6 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 VBB27155.1 - 3e-59 201.1 0.9 6e-59 200.1 0.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 VBB27155.1 - 1.1e-42 146.3 1.5 1.5e-36 126.3 0.1 2.6 1 1 0 2 2 2 2 Peptidase M1 N-terminal domain CDC45 PF02724.14 VBB27155.1 - 0.11 10.8 4.8 0.12 10.7 0.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Metallophos_C PF14008.6 VBB27156.1 - 2e-22 79.8 0.0 2e-22 79.8 0.0 2.6 3 1 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 VBB27156.1 - 5.2e-20 72.8 0.5 1.1e-19 71.8 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 VBB27156.1 - 3.1e-12 46.9 0.1 3.1e-12 46.9 0.1 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PTH2 PF01981.16 VBB27158.1 - 6.5e-23 81.3 0.1 1.3e-16 60.9 0.0 2.3 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 UBA PF00627.31 VBB27158.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF2623 PF11115.8 VBB27158.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) PH_15 PF17339.2 VBB27159.1 - 7.4e-35 119.1 0.0 1.4e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Cys_knot PF00007.22 VBB27160.1 - 5.5e-08 33.1 9.0 6.9e-08 32.7 9.0 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 VBB27160.1 - 5.8e-07 29.5 5.9 7.6e-07 29.2 5.9 1.1 1 0 0 1 1 1 1 DAN domain Aldedh PF00171.22 VBB27161.1 - 2.2e-75 253.9 0.0 3.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 VBB27161.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AAA_9 PF12781.7 VBB27162.1 - 1.4e-72 243.4 0.1 1.4e-72 243.4 0.1 3.8 4 0 0 4 4 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 VBB27162.1 - 2.4e-45 155.1 0.6 7e-45 153.6 0.6 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 VBB27162.1 - 5.6e-39 134.1 4.6 5.6e-39 134.1 4.6 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 VBB27162.1 - 2.7e-37 128.5 0.0 6.4e-37 127.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 VBB27162.1 - 3.9e-37 127.6 0.0 8.4e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 VBB27162.1 - 2.7e-27 95.2 0.0 1.2e-25 89.9 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain BRE1 PF08647.11 VBB27162.1 - 0.0018 18.3 2.3 0.0018 18.3 2.3 3.8 3 1 1 4 4 3 1 BRE1 E3 ubiquitin ligase DUF4795 PF16043.5 VBB27162.1 - 0.0054 16.4 0.2 0.0054 16.4 0.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4795) FapA PF03961.13 VBB27162.1 - 0.021 13.4 22.2 0.27 9.8 0.6 3.1 3 0 0 3 3 3 0 Flagellar Assembly Protein A APG6_N PF17675.1 VBB27162.1 - 0.023 15.2 0.8 0.023 15.2 0.8 4.5 3 1 1 4 4 4 0 Apg6 coiled-coil region Taxilin PF09728.9 VBB27162.1 - 0.057 12.6 24.2 0.49 9.5 24.2 2.2 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF948 PF06103.11 VBB27162.1 - 0.083 13.2 11.3 3.9 7.8 0.2 4.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 VBB27162.1 - 0.69 10.3 28.3 0.99 9.8 0.6 3.5 3 0 0 3 3 3 0 Fez1 GAS PF13851.6 VBB27162.1 - 3.5 6.9 28.5 0.19 11.0 0.6 3.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding V-SNARE_C PF12352.8 VBB27163.1 - 2.5e-09 37.3 0.3 8.6e-09 35.6 0.3 2.0 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus FliD_N PF02465.18 VBB27163.1 - 0.0056 17.4 1.1 0.4 11.4 0.1 2.5 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 N-terminus APG17 PF04108.12 VBB27163.1 - 0.018 14.2 0.9 0.018 14.2 0.9 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 Sad1_UNC PF07738.13 VBB27163.1 - 0.051 13.6 0.2 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal TipAS PF07739.13 VBB27163.1 - 0.13 12.8 0.5 0.89 10.1 0.2 2.3 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain BLOC1_2 PF10046.9 VBB27163.1 - 0.23 11.8 4.1 0.19 12.0 0.4 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 VBB27163.1 - 0.29 11.2 3.5 2.4 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCCH PF00642.24 VBB27164.1 - 2.1e-06 27.5 4.5 5.1e-06 26.3 4.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB27164.1 - 0.00078 19.4 7.2 0.0017 18.4 7.2 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 VBB27164.1 - 0.0037 17.9 0.4 0.01 16.6 0.4 1.8 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 VBB27164.1 - 0.015 15.1 4.2 0.027 14.3 4.2 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger WD40 PF00400.32 VBB27165.1 - 0.48 11.4 6.4 4.8 8.2 0.3 4.4 5 1 1 6 6 6 0 WD domain, G-beta repeat NNMT_PNMT_TEMT PF01234.17 VBB27166.1 - 1.2e-70 237.6 0.0 1.5e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.6 VBB27166.1 - 0.00013 22.6 0.0 0.37 11.5 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain NodS PF05401.11 VBB27166.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 VBB27166.1 - 0.072 13.8 0.0 0.33 11.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Rep_fac_C PF08542.11 VBB27168.1 - 3.7e-24 84.9 0.2 1.8e-23 82.8 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 VBB27168.1 - 7.4e-15 55.5 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 VBB27168.1 - 5e-14 52.4 0.0 4.9e-12 45.9 0.1 2.4 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 VBB27168.1 - 3.5e-08 33.5 0.0 5.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB27168.1 - 3.7e-08 33.9 0.0 8.4e-06 26.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 VBB27168.1 - 3.9e-07 30.2 0.0 2.9e-06 27.4 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 VBB27168.1 - 9.4e-07 28.8 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 VBB27168.1 - 3.2e-05 23.7 0.0 0.00024 20.9 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB27168.1 - 5.3e-05 23.5 0.1 0.094 13.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 VBB27168.1 - 7.8e-05 22.6 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB27168.1 - 0.00019 22.0 0.0 0.00036 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 VBB27168.1 - 0.00034 20.1 0.1 0.91 8.9 0.0 2.7 3 0 0 3 3 3 2 Bacterial TniB protein AAA_assoc_2 PF16193.5 VBB27168.1 - 0.00043 20.6 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_3 PF07726.11 VBB27168.1 - 0.00078 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 VBB27168.1 - 0.00091 19.6 0.0 0.0033 17.8 0.0 2.1 1 1 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 VBB27168.1 - 0.00097 19.1 0.1 0.11 12.4 0.0 2.5 1 1 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 VBB27168.1 - 0.0013 18.1 0.0 0.038 13.4 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 VBB27168.1 - 0.0019 18.5 0.0 0.0048 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 VBB27168.1 - 0.0022 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 VBB27168.1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 VBB27168.1 - 0.0029 18.0 0.1 0.038 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 VBB27168.1 - 0.0088 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 VBB27168.1 - 0.014 15.0 0.0 0.036 13.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 VBB27168.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 VBB27168.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 VBB27168.1 - 0.024 14.4 0.3 0.067 12.9 0.1 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 VBB27168.1 - 0.028 13.4 0.0 0.1 11.5 0.0 1.9 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 VBB27168.1 - 0.032 13.8 0.0 0.2 11.2 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 VBB27168.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 VBB27168.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NACHT PF05729.12 VBB27168.1 - 0.069 13.1 0.1 1.1 9.2 0.1 2.2 1 1 1 2 2 2 0 NACHT domain MCM PF00493.23 VBB27168.1 - 0.085 11.9 0.1 0.35 9.9 0.0 2.0 1 1 1 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 VBB27168.1 - 0.085 13.4 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 VBB27168.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 VBB27168.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 VBB27168.1 - 0.17 12.3 0.1 0.25 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain UbiA PF01040.18 VBB27169.1 - 3.3e-51 174.0 20.1 1.9e-33 115.8 6.0 2.1 1 1 1 2 2 2 2 UbiA prenyltransferase family ACBP PF00887.19 VBB27169.1 - 4.1e-13 49.3 0.1 8e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein SAP18 PF06487.12 VBB27170.1 - 2e-39 135.0 0.0 2.5e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) HCV_env PF01539.17 VBB27171.1 - 0.091 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 CssAB PF16831.5 VBB27172.1 - 0.0049 17.2 0.4 0.011 16.1 0.4 1.6 1 0 0 1 1 1 1 CS6 fimbrial subunits A and B, Coli surface antigen 6 DUF3682 PF12446.8 VBB27172.1 - 0.031 14.8 0.9 0.031 14.8 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) TFIIA PF03153.13 VBB27172.1 - 5.6 6.8 22.8 8.8 6.2 22.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sad1_UNC PF07738.13 VBB27173.1 - 1.3e-33 115.9 0.1 2.7e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4834 PF16118.5 VBB27173.1 - 2.1 9.4 5.6 31 5.6 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) zf-CCCH PF00642.24 VBB27174.1 - 1.7e-12 46.9 30.7 5.5e-07 29.3 1.2 4.8 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB27174.1 - 3.7e-09 36.3 11.4 1.1e-06 28.4 2.6 5.9 6 1 1 7 7 7 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB27174.1 - 5.1e-06 26.2 0.3 5.1e-06 26.2 0.3 4.9 5 0 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 VBB27174.1 - 6e-05 23.7 33.3 0.0024 18.5 1.4 5.6 2 1 4 6 6 6 4 Torus domain zf-CCCH_3 PF15663.5 VBB27174.1 - 0.028 14.6 20.5 0.11 12.8 2.4 4.0 1 1 2 3 3 3 0 Zinc-finger containing family zf-CCHC PF00098.23 VBB27174.1 - 0.22 11.7 26.4 0.055 13.6 6.2 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-C3H1 PF10650.9 VBB27174.1 - 0.35 10.6 14.0 4.1 7.2 0.8 4.1 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 VBB27174.1 - 2.6 8.7 30.6 0.4 11.2 1.0 5.3 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-CCHC_4 PF14392.6 VBB27174.1 - 5.9 6.7 9.9 3.4 7.5 3.8 2.6 2 0 0 2 2 2 0 Zinc knuckle Aconitase PF00330.20 VBB27175.1 - 0.022 13.7 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) RAWUL PF16207.5 VBB27175.1 - 0.036 14.7 0.0 0.077 13.7 0.0 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like PAX PF00292.18 VBB27176.1 - 4.4e-26 91.2 0.4 6.4e-26 90.7 0.4 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 VBB27176.1 - 6.1e-09 35.4 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 VBB27176.1 - 2.5e-05 24.0 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 VBB27176.1 - 3.3e-05 23.8 0.0 7.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 VBB27176.1 - 0.0034 17.5 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 VBB27176.1 - 0.012 15.5 0.3 0.025 14.4 0.3 1.5 1 0 0 1 1 1 0 Tc3 transposase PBP_sp32 PF07222.12 VBB27176.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 Terminase_5 PF06056.12 VBB27176.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF4817 PF16087.5 VBB27176.1 - 0.14 12.0 0.6 10 6.0 0.1 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain (DUF4817) RhoGEF PF00621.20 VBB27177.1 - 3.7e-38 131.6 1.0 7.5e-38 130.6 1.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 VBB27177.1 - 7.8e-13 48.2 0.3 9.6e-12 44.7 0.1 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 VBB27177.1 - 9.3e-07 29.1 0.0 0.0054 17.1 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 VBB27177.1 - 5.6e-05 23.4 0.2 0.0039 17.5 0.1 2.7 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 VBB27177.1 - 0.004 17.5 0.0 0.023 15.1 0.1 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Sec8_exocyst PF04048.14 VBB27177.1 - 0.038 13.9 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain IQ_SEC7_PH PF16453.5 VBB27177.1 - 0.084 12.9 0.4 0.29 11.1 0.4 2.0 1 1 0 1 1 1 0 PH domain DUF1540 PF07561.11 VBB27178.1 - 0.52 10.6 2.3 0.45 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) 7tm_3 PF00003.22 VBB27179.1 - 2.1e-53 181.5 23.4 2.1e-53 181.5 22.4 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 VBB27179.1 - 6.9e-39 133.9 0.0 9.6e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2976 PF11190.8 VBB27179.1 - 0.0022 17.8 8.7 0.033 14.0 1.6 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2976) DUF4834 PF16118.5 VBB27179.1 - 2.3 9.2 5.1 3.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ATP-synt_8 PF00895.20 VBB27179.1 - 2.6 8.6 4.7 9.4 6.8 0.2 3.0 2 1 0 2 2 2 0 ATP synthase protein 8 SMG1 PF15785.5 VBB27180.1 - 8.9e-58 196.2 10.6 1.2e-56 192.4 10.6 2.7 1 1 0 1 1 1 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 VBB27180.1 - 1.8e-54 185.2 0.4 7.1e-54 183.3 0.0 2.3 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 VBB27180.1 - 7.2e-13 48.1 0.4 7.2e-13 48.1 0.4 2.1 2 0 0 2 2 2 1 FATC domain DUF4378 PF14309.6 VBB27180.1 - 9.3 6.6 11.0 3 8.2 1.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) Nop PF01798.18 VBB27184.1 - 1.4e-82 276.7 0.1 2.5e-82 275.8 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Glyco_transf_90 PF05686.12 VBB27184.1 - 3.5e-57 194.1 3.8 5.2e-57 193.6 3.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 NOP5NT PF08156.13 VBB27184.1 - 3e-23 82.0 0.4 8.4e-23 80.5 0.4 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Pribosyltran PF00156.27 VBB27185.1 - 1.7e-14 53.6 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 VBB27185.1 - 0.0041 16.6 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 VBB27185.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Zip PF02535.22 VBB27186.1 - 2.7e-68 230.6 5.8 3.6e-68 230.2 5.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 VBB27186.1 - 0.019 14.5 7.8 0.12 11.9 1.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1129) OrfB_Zn_ribbon PF07282.11 VBB27186.1 - 0.086 12.8 1.7 0.36 10.8 0.4 2.5 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DUF4212 PF13937.6 VBB27186.1 - 0.28 11.6 8.3 2.1 8.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) CitMHS PF03600.16 VBB27186.1 - 4.5 6.4 11.5 0.41 9.8 1.8 2.3 2 0 0 2 2 2 0 Citrate transporter PDZ PF00595.24 VBB27187.1 - 3.9e-17 62.4 1.5 1.8e-07 31.4 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB27187.1 - 8.5e-12 44.7 0.1 0.00011 21.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB27187.1 - 0.0022 18.3 0.5 2.1 8.7 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB27188.1 - 3.6e-25 88.1 0.0 1.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB27188.1 - 1.4e-18 66.4 0.0 2.3e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB27188.1 - 3.2e-12 46.6 0.0 9.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PCSK9_C1 PF18459.1 VBB27188.1 - 0.04 14.1 1.6 2.5 8.3 0.1 2.8 3 0 0 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Tricorn_PDZ PF14685.6 VBB27188.1 - 0.045 13.7 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Tricorn protease PDZ domain Spt4 PF06093.13 VBB27188.1 - 0.046 13.8 0.7 0.11 12.7 0.3 1.8 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger Ribosomal_L31e PF01198.19 VBB27189.1 - 4.9e-40 135.6 0.4 1.2e-39 134.4 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L31e zf-RING_5 PF14634.6 VBB27189.1 - 0.95 9.5 3.6 37 4.4 0.0 2.9 2 0 0 2 2 2 0 zinc-RING finger domain CCDC53 PF10152.9 VBB27191.1 - 1.7e-35 122.7 0.9 1.7e-35 122.7 0.9 1.4 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex DUF4861 PF16153.5 VBB27191.1 - 0.0008 18.5 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4861) LOH1CR12 PF10158.9 VBB27192.1 - 1.2e-21 77.0 0.6 2.9e-17 62.9 0.1 2.3 1 1 1 2 2 2 2 Tumour suppressor protein BLOC1_2 PF10046.9 VBB27192.1 - 0.046 14.0 0.5 0.13 12.5 0.5 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MnmE_helical PF12631.7 VBB27192.1 - 0.06 13.5 0.5 0.14 12.3 0.5 1.6 1 1 0 1 1 1 0 MnmE helical domain Acetyltransf_1 PF00583.25 VBB27193.1 - 1.5e-10 41.4 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB27193.1 - 2e-06 27.7 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 VBB27193.1 - 1.4e-05 25.5 0.1 2.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3855 PF12967.7 VBB27195.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) Methyltransf_15 PF09445.10 VBB27196.1 - 3.4e-37 127.6 0.1 1e-36 126.0 0.1 1.8 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 VBB27196.1 - 2.7e-05 24.0 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein LPD1 PF18796.1 VBB27196.1 - 0.018 15.1 0.9 0.075 13.2 0.1 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 1 UPF0020 PF01170.18 VBB27196.1 - 0.021 14.5 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 BAR PF03114.18 VBB27197.1 - 7.3e-12 45.4 10.7 9.2e-12 45.1 10.7 1.0 1 0 0 1 1 1 1 BAR domain UPF0184 PF03670.13 VBB27197.1 - 0.012 16.0 1.6 0.051 14.0 0.4 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) nsp7 PF08716.10 VBB27197.1 - 0.032 14.8 0.0 0.086 13.5 0.0 1.7 1 0 0 1 1 1 0 nsp7 replicase Tox-REase-2 PF15646.6 VBB27197.1 - 0.034 14.3 6.5 0.49 10.6 1.8 2.2 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 Syntaxin-6_N PF09177.11 VBB27197.1 - 0.038 14.5 2.1 0.038 14.5 2.1 2.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FliG_C PF01706.16 VBB27197.1 - 0.13 12.4 6.2 1.7 8.8 1.7 2.7 1 1 1 2 2 2 0 FliG C-terminal domain ATP-synt_B PF00430.18 VBB27197.1 - 0.47 10.5 4.1 0.9 9.6 1.2 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Tropomyosin_1 PF12718.7 VBB27197.1 - 0.69 10.1 13.1 0.2 11.8 9.4 1.8 1 1 1 2 2 2 0 Tropomyosin like GlutR_dimer PF00745.20 VBB27197.1 - 1.1 9.7 7.2 1.7 9.1 1.2 3.2 1 1 2 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain RRF PF01765.19 VBB27197.1 - 10 6.1 16.9 1.5 8.8 6.1 2.8 1 1 2 3 3 3 0 Ribosome recycling factor TRIC PF05197.13 VBB27198.1 - 4.7e-82 274.2 1.9 6.7e-82 273.7 1.9 1.2 1 0 0 1 1 1 1 TRIC channel SHP PF03579.13 VBB27198.1 - 0.15 12.0 1.9 0.91 9.5 0.0 2.8 2 1 1 3 3 3 0 Small hydrophobic protein CAF1 PF04857.20 VBB27199.1 - 1.6e-65 221.4 0.0 3.6e-35 121.6 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease WD40 PF00400.32 VBB27200.1 - 1.5e-20 73.1 1.8 2.9e-05 24.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.21 VBB27200.1 - 1.5e-13 50.7 9.0 3.5e-13 49.5 9.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger Nucleoporin_N PF08801.11 VBB27200.1 - 1.9e-06 26.9 0.1 0.052 12.3 0.1 3.2 2 1 1 3 3 3 3 Nup133 N terminal like ANAPC4_WD40 PF12894.7 VBB27200.1 - 0.00094 19.4 0.0 0.0081 16.4 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 VBB27200.1 - 0.022 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region SUKH_6 PF14568.6 VBB27200.1 - 0.15 12.5 0.0 29 5.1 0.0 2.7 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall Myosin_head PF00063.21 VBB27201.1 - 4.5e-274 910.8 7.6 5.2e-274 910.6 7.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 VBB27201.1 - 1.8e-12 46.8 2.7 4.2e-12 45.7 2.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 VBB27201.1 - 0.051 13.9 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 VBB27201.1 - 0.075 12.1 0.4 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 VBB27201.1 - 0.096 12.7 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 VBB27201.1 - 0.11 12.8 0.2 0.3 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain Carn_acyltransf PF00755.20 VBB27202.1 - 1.2e-77 261.9 0.0 1.5e-77 261.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Membralin PF09746.9 VBB27202.1 - 0.052 12.6 1.7 0.079 12.0 1.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein Spore_permease PF03845.13 VBB27202.1 - 0.087 11.6 2.0 0.14 11.0 2.0 1.2 1 0 0 1 1 1 0 Spore germination protein Carn_acyltransf PF00755.20 VBB27203.1 - 1.1e-66 225.7 0.2 1.2e-66 225.6 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YchF-GTPase_C PF06071.13 VBB27203.1 - 0.091 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Glyco_hydro_31 PF01055.26 VBB27204.1 - 3.8e-145 484.5 3.4 5.9e-145 483.8 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 VBB27204.1 - 1.3e-20 73.5 0.1 2.4e-19 69.4 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 VBB27204.1 - 3e-06 27.4 1.9 1e-05 25.7 1.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Ecm29 PF13001.7 VBB27205.1 - 2.7e-77 260.5 4.5 2.7e-77 260.5 4.5 3.0 3 0 0 3 3 3 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 VBB27205.1 - 3.3e-07 30.8 5.0 7.9e-05 23.2 0.2 6.2 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 VBB27205.1 - 5.6e-07 29.3 6.0 0.43 11.0 0.0 8.1 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 VBB27205.1 - 0.0004 20.8 0.6 22 5.7 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 VBB27205.1 - 0.0021 18.4 2.3 4.8 7.6 0.1 5.9 5 1 2 7 7 7 1 HEAT repeats DRMBL PF07522.14 VBB27205.1 - 0.005 17.0 0.1 0.017 15.3 0.1 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Cnd1 PF12717.7 VBB27205.1 - 0.0065 16.5 18.0 0.14 12.2 0.3 5.7 7 0 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Lactamase_B_2 PF12706.7 VBB27205.1 - 0.094 12.2 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ENTH PF01417.20 VBB27205.1 - 0.1 12.6 1.1 27 4.8 0.2 3.3 2 0 0 2 2 2 0 ENTH domain Lactamase_B PF00753.27 VBB27205.1 - 0.19 11.7 3.0 0.53 10.2 3.0 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily SNF2_N PF00176.23 VBB27207.1 - 1.8e-52 178.2 0.8 3.5e-52 177.2 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB27207.1 - 2.4e-17 63.3 0.0 7.7e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.8 VBB27207.1 - 2.9e-12 46.6 0.0 1.1e-10 41.3 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3535) HEAT PF02985.22 VBB27207.1 - 4.3e-12 45.2 16.0 0.045 14.0 0.0 8.4 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.6 VBB27207.1 - 2.4e-11 43.9 11.7 0.033 14.7 0.0 8.2 9 0 0 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.6 VBB27207.1 - 5.7e-08 33.0 6.7 6.6e-05 23.2 0.1 5.2 4 1 0 4 4 4 2 HEAT repeats Transketolase_C PF02780.20 VBB27207.1 - 0.0035 17.2 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain HEAT_PBS PF03130.16 VBB27207.1 - 0.014 16.0 0.1 0.95 10.3 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat ERCC3_RAD25_C PF16203.5 VBB27207.1 - 0.12 11.6 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Metallophos PF00149.28 VBB27208.1 - 2.2e-06 28.3 0.0 3.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB27208.1 - 0.034 14.6 0.0 0.081 13.4 0.0 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Tyr-DNA_phospho PF06087.12 VBB27209.1 - 2e-91 307.0 0.0 2.7e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Peptidase_C48 PF02902.19 VBB27209.1 - 1.6e-12 47.7 0.1 2.8e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Gp-FAR-1 PF05823.12 VBB27209.1 - 0.065 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Pyr_redox_2 PF07992.14 VBB27210.1 - 3.6e-48 164.3 0.0 9.1e-48 163.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 VBB27210.1 - 5.1e-26 91.1 0.1 1.4e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 VBB27210.1 - 1.6e-16 60.6 1.4 2.2e-13 50.6 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 VBB27210.1 - 1.8e-06 27.4 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 VBB27210.1 - 0.00018 20.8 0.0 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 VBB27210.1 - 0.002 17.3 2.7 0.0038 16.4 2.7 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 VBB27210.1 - 0.0052 16.2 0.1 0.0078 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 VBB27210.1 - 0.008 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 VBB27210.1 - 0.071 12.2 0.1 0.97 8.5 0.0 2.4 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Glutaredoxin PF00462.24 VBB27210.1 - 0.084 13.1 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin DAO PF01266.24 VBB27210.1 - 0.098 12.2 0.1 0.44 10.1 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 VBB27210.1 - 0.15 10.7 0.5 0.24 10.0 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 VBB27210.1 - 0.34 9.9 1.1 0.53 9.3 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Copine PF07002.16 VBB27211.1 - 1.2e-34 119.6 0.0 1.8e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Copine MSV199 PF10553.9 VBB27211.1 - 0.024 14.9 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 MSV199 domain PCI PF01399.27 VBB27213.1 - 1.4e-17 64.1 3.1 2.1e-17 63.6 0.9 2.4 2 1 0 2 2 2 1 PCI domain RPN6_N PF18055.1 VBB27213.1 - 9e-17 61.5 3.4 9.4e-17 61.5 0.5 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain CRISPR_Cse2 PF09485.10 VBB27213.1 - 0.073 13.6 0.0 0.55 10.7 0.0 2.4 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DSHCT PF08148.12 VBB27213.1 - 0.077 12.7 0.7 0.28 10.8 0.0 2.2 2 1 0 2 2 2 0 DSHCT (NUC185) domain DNA_topoisoIV PF00521.20 VBB27214.1 - 5.7e-111 371.4 0.0 1.2e-110 370.3 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 VBB27214.1 - 8.2e-39 132.8 2.4 2.7e-38 131.1 2.4 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 VBB27214.1 - 5.4e-21 74.8 3.3 1.2e-20 73.7 0.1 2.5 2 0 0 2 2 2 1 DNA gyrase B SAM_2 PF07647.17 VBB27214.1 - 6.4e-20 71.0 0.6 9.3e-11 41.7 0.1 2.9 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 VBB27214.1 - 2.6e-14 53.4 2.3 3.3e-12 46.7 0.3 2.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HATPase_c PF02518.26 VBB27214.1 - 2.1e-13 50.8 0.0 6.5e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TIR_2 PF13676.6 VBB27214.1 - 2.2e-10 41.1 0.0 8.4e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 TIR domain Toprim PF01751.22 VBB27214.1 - 1.9e-06 28.0 0.0 9.7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain CENP-R PF06729.12 VBB27214.1 - 0.016 15.1 0.3 0.056 13.4 0.1 2.0 2 0 0 2 2 2 0 Kinetochore component, CENP-R DNA_gyraseB_C PF00986.21 VBB27214.1 - 0.083 13.1 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus DUF1758 PF05585.12 VBB27217.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) PNP_UDP_1 PF01048.20 VBB27218.1 - 2.9e-39 134.7 0.0 3.4e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Yip1 PF04893.17 VBB27219.1 - 8.3e-08 32.1 7.1 1.3e-07 31.5 7.1 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 VBB27219.1 - 0.045 13.3 8.4 11 5.5 8.4 2.3 1 1 0 1 1 1 0 YIF1 TDP43_N PF18694.1 VBB27220.1 - 3.8e-22 77.9 0.0 6.7e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 VBB27220.1 - 2.1e-18 65.9 1.9 1.5e-14 53.6 0.4 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 VBB27220.1 - 0.008 16.4 0.1 13 6.0 0.0 3.1 1 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 VBB27220.1 - 0.025 14.6 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif SET PF00856.28 VBB27221.1 - 6.9e-23 81.9 0.3 2e-22 80.3 0.3 1.9 1 0 0 1 1 1 1 SET domain Ank_3 PF13606.6 VBB27221.1 - 0.00068 19.9 0.6 0.63 10.8 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 VBB27221.1 - 0.0015 19.0 0.1 0.088 13.4 0.0 2.6 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB27221.1 - 0.0088 16.6 0.8 19 6.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) MIP PF00230.20 VBB27223.1 - 1.2e-07 31.6 13.3 1e-06 28.6 8.6 2.0 1 1 1 2 2 2 2 Major intrinsic protein E1-E2_ATPase PF00122.20 VBB27224.1 - 2e-44 151.3 5.9 2.3e-44 151.1 2.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 VBB27224.1 - 1.3e-39 135.8 2.6 1.3e-39 135.8 2.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 VBB27224.1 - 7.5e-24 85.2 0.0 2.3e-21 77.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 VBB27224.1 - 1.4e-21 76.4 0.3 3.3e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 VBB27224.1 - 7.5e-12 44.8 0.1 1.5e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 VBB27224.1 - 0.0013 19.2 0.0 0.01 16.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 VBB27224.1 - 0.0013 18.5 8.9 0.0051 16.6 5.5 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Diphtheria_T PF02764.14 VBB27224.1 - 0.023 14.7 0.2 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Diphtheria toxin, T domain Tetraspanin PF00335.20 VBB27224.1 - 1.4 8.5 7.2 0.24 11.1 0.9 2.5 2 0 0 2 2 2 0 Tetraspanin family Patched PF02460.18 VBB27225.1 - 7.5e-147 490.7 21.1 7.3e-84 282.4 8.9 3.0 1 1 2 3 3 3 3 Patched family Sterol-sensing PF12349.8 VBB27225.1 - 1.2e-20 73.9 1.2 1.2e-20 73.9 1.2 4.0 5 0 0 5 5 5 1 Sterol-sensing domain of SREBP cleavage-activation Glu-tRNAGln PF02686.15 VBB27225.1 - 0.08 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit NIF PF03031.18 VBB27227.1 - 1.5e-52 177.5 0.1 2.4e-52 176.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF780 PF05611.11 VBB27228.1 - 0.0021 18.8 11.3 0.0021 18.8 11.3 3.2 2 1 1 3 3 3 1 Caenorhabditis elegans protein of unknown function (DUF780) CAP_N PF01213.19 VBB27228.1 - 0.18 11.2 2.9 0.21 11.0 2.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 VBB27228.1 - 0.42 10.6 5.6 0.58 10.2 5.6 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 G-patch PF01585.23 VBB27229.1 - 9.3e-14 51.1 2.4 1.5e-13 50.4 2.4 1.3 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.7 VBB27229.1 - 7.6e-09 35.7 0.1 1.1e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 VBB27229.1 - 5e-08 33.5 0.1 1e-07 32.5 0.0 1.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif G-patch_2 PF12656.7 VBB27229.1 - 0.0029 17.7 0.2 0.03 14.4 0.3 2.0 2 0 0 2 2 2 1 G-patch domain dsRBD2 PF17842.1 VBB27229.1 - 0.0093 16.2 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 Cadherin PF00028.17 VBB27230.1 - 2.3e-10 40.8 0.2 7.2e-06 26.4 0.0 2.9 2 1 0 2 2 2 2 Cadherin domain MAF_flag10 PF01973.18 VBB27232.1 - 0.0075 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF115 Cadherin PF00028.17 VBB27232.1 - 0.013 15.9 0.0 0.54 10.7 0.0 2.8 3 0 0 3 3 3 0 Cadherin domain MoaE PF02391.17 VBB27233.1 - 5.9e-33 113.5 0.0 1.1e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 MoaE protein MobB PF03205.14 VBB27233.1 - 7.5e-05 22.6 0.1 0.00031 20.6 0.1 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 VBB27233.1 - 0.00015 21.6 0.4 0.024 14.4 0.1 2.3 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 VBB27233.1 - 0.0004 20.9 0.0 0.0036 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 VBB27233.1 - 0.0035 16.4 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 VBB27233.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 VBB27233.1 - 0.012 15.5 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase CLP1_P PF16575.5 VBB27233.1 - 0.019 14.8 0.1 0.065 13.0 0.0 1.9 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop dNK PF01712.19 VBB27233.1 - 0.081 12.8 0.5 9.8 6.0 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase SRP54 PF00448.22 VBB27233.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 VBB27233.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 VBB27233.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SMC_Nse1 PF07574.13 VBB27235.1 - 9e-07 29.0 0.1 0.00018 21.5 0.1 2.4 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Prok-RING_1 PF14446.6 VBB27235.1 - 0.00027 20.8 0.9 0.00052 19.9 0.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 VBB27235.1 - 0.0095 15.8 4.0 0.02 14.8 4.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 VBB27235.1 - 0.028 14.6 2.4 0.071 13.3 2.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger PHD PF00628.29 VBB27235.1 - 0.081 12.8 5.9 0.038 13.9 3.2 1.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 VBB27235.1 - 0.19 12.1 2.8 0.37 11.2 2.8 1.5 1 0 0 1 1 1 0 Ring finger domain Peptidase_C65 PF10275.9 VBB27238.1 - 3.1e-16 59.6 0.2 3.1e-16 59.6 0.2 1.5 2 0 0 2 2 2 1 Peptidase C65 Otubain ZnuA PF01297.17 VBB27238.1 - 0.11 11.9 0.4 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic I-set PF07679.16 VBB27239.1 - 1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB27239.1 - 1.5e-05 25.5 0.0 2.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain PAS_10 PF13596.6 VBB27239.1 - 0.11 13.1 0.0 0.98 10.0 0.0 2.1 2 0 0 2 2 2 0 PAS domain Myb_DNA-binding PF00249.31 VBB27240.1 - 2.8e-49 165.0 17.6 1.5e-12 47.5 0.0 6.6 6 0 0 6 6 6 6 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 VBB27240.1 - 9.4e-43 144.3 11.0 2.4e-09 37.3 0.1 6.1 2 1 3 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 VBB27240.1 - 0.00017 21.4 1.0 0.087 12.7 0.0 4.7 2 1 3 5 5 5 1 Myb DNA-binding like SRP54_N PF02881.19 VBB27240.1 - 0.13 12.5 2.7 0.21 11.8 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain KLRAQ PF10205.9 VBB27241.1 - 9.7e-20 70.7 9.5 9.7e-20 70.7 9.5 4.1 3 1 1 4 4 4 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 VBB27241.1 - 1.7e-19 70.2 37.8 8.6e-14 51.4 7.9 4.9 3 2 1 4 4 4 3 Predicted coiled-coil domain-containing protein Filament PF00038.21 VBB27241.1 - 0.00016 21.4 43.9 0.0091 15.6 13.3 2.7 2 1 0 2 2 2 2 Intermediate filament protein BRE1 PF08647.11 VBB27241.1 - 0.017 15.1 8.4 0.017 15.1 8.4 5.3 3 2 2 5 5 5 0 BRE1 E3 ubiquitin ligase DUF4709 PF15821.5 VBB27241.1 - 0.48 10.7 12.9 0.24 11.7 3.3 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) HalX PF08663.10 VBB27241.1 - 1.3 9.4 20.8 0.096 13.0 2.4 4.9 5 0 0 5 5 5 0 HalX domain DUF4472 PF14739.6 VBB27241.1 - 2.3 9.0 36.4 2.1 9.1 5.6 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4472) Rootletin PF15035.6 VBB27241.1 - 6.9 6.6 36.7 4.6 7.2 3.5 4.6 3 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 VBB27241.1 - 9.1 6.4 44.4 0.082 13.0 4.9 4.9 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein PHD PF00628.29 VBB27242.1 - 1.6e-18 66.3 19.4 1.2e-09 38.0 4.5 2.3 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 VBB27242.1 - 5.6e-07 29.0 17.0 0.00062 19.3 7.0 2.9 2 1 1 3 3 3 2 PHD-finger C1_1 PF00130.22 VBB27242.1 - 1.5e-06 28.0 13.8 8.9e-05 22.3 1.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB27242.1 - 4.4e-06 26.9 13.9 5.6e-05 23.4 0.4 2.6 2 0 0 2 2 2 2 C1 domain PHD_4 PF16866.5 VBB27242.1 - 0.00067 19.7 12.8 0.00067 19.7 12.8 3.0 1 1 1 2 2 2 1 PHD-finger Zn_ribbon_17 PF17120.5 VBB27242.1 - 0.0033 17.0 1.9 0.0033 17.0 1.9 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 VBB27242.1 - 0.0084 16.3 15.6 0.032 14.4 5.1 2.5 1 1 1 2 2 2 1 PHD-zinc-finger like domain Requiem_N PF14051.6 VBB27242.1 - 0.021 15.0 1.4 0.033 14.4 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. Ca_bind_SSO6904 PF18249.1 VBB27242.1 - 0.078 13.3 0.4 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 Calcium binding protein SSO6904 Phage_GPL PF05926.11 VBB27242.1 - 0.15 12.1 1.8 0.27 11.2 1.8 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) Zf_RING PF16744.5 VBB27242.1 - 0.89 9.7 18.3 19 5.5 6.6 2.8 1 1 1 2 2 2 0 KIAA1045 RING finger OrfB_Zn_ribbon PF07282.11 VBB27242.1 - 4.5 7.3 15.2 0.39 10.7 1.9 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DUF5449 PF17528.2 VBB27243.1 - 0.47 10.2 1.9 6.8 6.4 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5449) ARID PF01388.21 VBB27244.1 - 1.4e-20 73.7 0.0 4.5e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RBB1NT PF08169.11 VBB27244.1 - 3.2e-11 43.2 0.1 1.5e-10 41.1 0.1 2.3 1 0 0 1 1 1 1 RBB1NT (NUC162) domain Tudor-knot PF11717.8 VBB27244.1 - 0.00039 20.2 4.1 0.00088 19.1 1.5 3.0 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain ProQ_C PF17516.2 VBB27244.1 - 0.25 10.8 1.1 0.56 9.7 1.1 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain RNase_H PF00075.24 VBB27245.1 - 4.9e-08 33.3 0.1 0.0082 16.3 0.0 2.4 2 0 0 2 2 2 2 RNase H RVT_3 PF13456.6 VBB27245.1 - 0.00028 20.7 0.2 0.01 15.6 0.2 2.5 2 0 0 2 2 2 1 Reverse transcriptase-like Claudin_2 PF13903.6 VBB27246.1 - 2.3e-07 30.8 0.2 2.8e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 VBB27246.1 - 0.078 12.8 0.5 0.1 12.4 0.5 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family TMEM174 PF15029.6 VBB27246.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.3 1 1 0 1 1 1 0 Transmembrane protein 174 GTP_EFTU PF00009.27 VBB27247.1 - 2.9e-23 82.4 0.0 5.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 VBB27247.1 - 1.8e-06 28.3 0.1 7.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 VBB27247.1 - 0.00084 19.6 1.9 0.0045 17.3 1.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 VBB27247.1 - 0.00091 19.3 0.1 0.0027 17.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB27247.1 - 0.031 14.2 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase RRM_1 PF00076.22 VBB27248.1 - 5.8e-18 64.5 0.1 1e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 VBB27250.1 - 6.9e-41 140.7 0.0 2.3e-40 139.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 VBB27250.1 - 8.7e-15 54.2 0.0 3.1e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 FATC domain Homeodomain PF00046.29 VBB27251.1 - 0.0033 17.2 0.1 0.0055 16.5 0.1 1.3 1 0 0 1 1 1 1 Homeodomain WD40 PF00400.32 VBB27253.1 - 1.6e-08 35.0 2.4 0.00095 19.9 0.0 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 VBB27253.1 - 0.00046 19.6 0.6 0.0021 17.5 0.6 1.9 1 1 0 1 1 1 1 WD40-like domain Na_H_Exchanger PF00999.21 VBB27254.1 - 3.6e-50 170.8 25.6 4.6e-50 170.5 25.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2518 PF10726.9 VBB27254.1 - 0.024 14.3 1.7 0.065 12.9 1.7 1.7 1 0 0 1 1 1 0 Protein of function (DUF2518) Sm_multidrug_ex PF06695.11 VBB27254.1 - 9.6 6.9 10.6 0.59 10.8 0.1 3.4 2 1 2 4 4 4 0 Putative small multi-drug export protein 7tm_3 PF00003.22 VBB27255.1 - 1e-48 166.1 20.7 1.6e-48 165.5 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 VBB27255.1 - 3.2e-12 46.2 11.3 7.1e-12 45.1 11.3 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Furin-like_2 PF15913.5 VBB27255.1 - 0.015 15.5 2.3 0.038 14.1 2.3 1.6 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich ZYG-11_interact PF05884.12 VBB27256.1 - 0.061 12.7 0.2 0.087 12.2 0.2 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 SPASM PF13186.6 VBB27256.1 - 0.1 13.1 1.2 0.25 11.9 1.2 1.9 1 1 0 1 1 1 0 Iron-sulfur cluster-binding domain SNF PF00209.18 VBB27257.1 - 2.4e-153 511.6 38.4 3.3e-153 511.1 38.4 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ost5 PF05251.12 VBB27257.1 - 0.01 16.0 2.5 0.01 16.0 2.5 3.5 5 0 0 5 5 5 0 Oligosaccharyltransferase subunit 5 Phage_holin_3_3 PF16083.5 VBB27257.1 - 1.8 8.8 9.4 6 7.1 0.2 3.9 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III Abhydrolase_9_N PF15420.6 VBB27257.1 - 8.4 6.3 7.8 4.9 7.1 4.4 2.4 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus COPIIcoated_ERV PF07970.12 VBB27258.1 - 2.6e-34 119.0 0.5 4.6e-34 118.2 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 VBB27258.1 - 1.6e-27 95.7 0.7 3.8e-27 94.4 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Innexin PF00876.18 VBB27259.1 - 7.2e-122 407.0 12.1 8.6e-122 406.8 12.1 1.1 1 0 0 1 1 1 1 Innexin CPSF73-100_C PF11718.8 VBB27260.1 - 1.6e-36 125.9 1.2 7.9e-36 123.6 0.7 2.2 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RMMBL PF07521.12 VBB27260.1 - 9.7e-19 67.1 0.0 1.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain KH_4 PF13083.6 VBB27260.1 - 0.11 12.3 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 KH domain Glycos_transf_2 PF00535.26 VBB27261.1 - 2.5e-24 86.0 0.0 4.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB27261.1 - 7.2e-13 48.9 0.2 1.2e-12 48.2 0.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 VBB27261.1 - 3e-07 30.0 0.0 7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 VBB27261.1 - 0.00012 21.6 0.0 0.00039 20.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 PMR5N PF14416.6 VBB27261.1 - 0.058 13.7 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 PMR5 N terminal Domain 2-oxoacid_dh PF00198.23 VBB27262.1 - 1.2e-72 244.2 0.5 1.7e-72 243.6 0.0 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) EMP24_GP25L PF01105.24 VBB27262.1 - 6.6e-53 179.3 0.2 1.5e-52 178.2 0.2 1.6 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.25 VBB27262.1 - 5.2e-22 78.3 0.0 2.1e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Biotin_lipoyl PF00364.22 VBB27262.1 - 1.1e-16 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme adh_short_C2 PF13561.6 VBB27262.1 - 6e-15 55.4 0.0 1.3e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB27262.1 - 2e-05 24.6 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Biotin_lipoyl_2 PF13533.6 VBB27262.1 - 0.0014 18.4 0.1 0.0096 15.7 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 VBB27262.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein Epimerase PF01370.21 VBB27262.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HlyD_D23 PF16576.5 VBB27262.1 - 0.03 13.5 0.7 0.058 12.6 0.0 1.7 2 0 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RNase_H_2 PF13482.6 VBB27263.1 - 0.002 18.1 0.2 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 RNase_H superfamily Sds3 PF08598.11 VBB27264.1 - 0.00021 21.4 16.1 0.00021 21.4 16.1 2.2 2 0 0 2 2 2 1 Sds3-like SICA_beta PF12878.7 VBB27264.1 - 0.011 16.0 1.9 0.011 16.0 1.9 2.1 3 0 0 3 3 3 0 SICA extracellular beta domain CFAP91 PF14738.6 VBB27264.1 - 0.013 15.6 13.3 0.013 15.6 13.3 1.9 1 1 1 2 2 2 0 Cilia- and flagella-associated protein 91 SprA-related PF12118.8 VBB27264.1 - 0.34 10.0 3.4 0.58 9.2 3.4 1.3 1 0 0 1 1 1 0 SprA-related family CENP-O PF09496.10 VBB27264.1 - 1.5 8.7 9.0 3 7.8 8.8 1.6 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Mak10 PF04112.13 VBB27265.1 - 1e-25 90.2 2.5 7.6e-19 67.8 0.7 2.7 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_S2 PF00318.20 VBB27266.1 - 5e-33 114.1 2.1 2.6e-17 62.8 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Apt1 PF10351.9 VBB27267.1 - 4.6e-93 312.7 9.6 1e-61 209.3 6.1 2.4 1 1 1 2 2 2 2 Golgi-body localisation protein domain DUF3246 PF11596.8 VBB27268.1 - 0.0083 15.6 2.8 0.0083 15.6 2.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3246) Ribosomal_L14 PF00238.19 VBB27270.1 - 1e-37 128.9 0.1 1.2e-37 128.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e JAB PF01398.21 VBB27271.1 - 5.6e-34 116.6 0.1 9.6e-34 115.9 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 VBB27271.1 - 2e-17 63.9 3.2 8.1e-17 61.9 3.2 2.0 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 VBB27271.1 - 2.2e-05 24.2 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 VBB27271.1 - 0.036 14.1 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) AD PF09793.9 VBB27272.1 - 2.1e-18 66.2 0.6 4e-18 65.3 0.6 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Herpes_UL79 PF03049.14 VBB27272.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 UL79 family N6-adenineMlase PF10237.9 VBB27273.1 - 1.3e-39 135.5 0.9 3.5e-39 134.2 0.2 2.1 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase ROQ_II PF18386.1 VBB27273.1 - 3e-34 116.6 1.5 8.5e-34 115.2 1.5 1.9 1 0 0 1 1 1 1 Roquin II domain Prok-RING_4 PF14447.6 VBB27273.1 - 7.7e-05 22.5 0.7 7.7e-05 22.5 0.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 VBB27273.1 - 0.00027 20.9 0.9 0.0017 18.3 0.9 2.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 VBB27273.1 - 0.0012 18.8 1.1 0.0012 18.8 1.1 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 VBB27273.1 - 0.0019 18.5 4.4 0.0071 16.7 0.9 3.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 VBB27273.1 - 0.006 16.7 1.2 0.006 16.7 1.2 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING PaaA_PaaC PF05138.12 VBB27273.1 - 0.021 14.0 0.1 0.045 12.9 0.1 1.5 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein zf-C3HC4_2 PF13923.6 VBB27273.1 - 1.1 9.2 8.2 0.04 13.8 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HP0268 PF18618.1 VBB27273.1 - 2.2 8.7 5.2 0.98 9.9 1.1 2.6 3 0 0 3 3 3 0 HP0268 Pkinase PF00069.25 VBB27274.1 - 2.4e-11 43.5 0.0 5.7e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27274.1 - 4.3e-07 29.5 0.0 1.4e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pneumo_M2 PF07380.11 VBB27274.1 - 0.064 13.5 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Pneumovirus M2 protein AdoMet_MTase PF07757.13 VBB27276.1 - 2.9e-34 117.8 0.2 5.8e-34 116.8 0.2 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase RRM_1 PF00076.22 VBB27276.1 - 2.4e-12 46.5 0.0 2.4e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MetW PF07021.12 VBB27276.1 - 0.0021 17.7 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 VBB27276.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 VBB27276.1 - 0.19 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Exonuc_VII_L PF02601.15 VBB27277.1 - 0.39 10.2 13.0 0.53 9.8 13.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 VBB27277.1 - 2.4 8.8 11.9 8.6 7.1 0.2 4.0 2 2 2 4 4 4 0 SlyX ABC_tran_CTD PF16326.5 VBB27277.1 - 3.9 7.8 11.7 0.12 12.7 3.8 2.5 1 1 1 3 3 3 0 ABC transporter C-terminal domain Atg14 PF10186.9 VBB27277.1 - 5.4 6.0 19.2 9.9 5.1 18.5 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Acetyltransf_1 PF00583.25 VBB27278.1 - 1.1e-12 48.2 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB27278.1 - 2e-10 40.7 0.1 3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 VBB27278.1 - 6.9e-10 39.2 0.1 1e-09 38.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 VBB27278.1 - 1.5e-05 25.2 0.1 3e-05 24.2 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 VBB27278.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 VBB27278.1 - 0.0026 17.8 0.0 0.0049 16.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 VBB27278.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BIR PF00653.21 VBB27280.1 - 7e-22 77.9 0.4 1.1e-21 77.3 0.4 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 VBB27280.1 - 0.00039 20.5 0.0 0.00055 20.0 0.0 1.6 1 1 0 1 1 1 1 C3HC zinc finger-like DUF1644 PF07800.12 VBB27280.1 - 0.03 14.4 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) CdiI_3 PF18616.1 VBB27280.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 CDI immunity proteins MerR-DNA-bind PF09278.11 VBB27280.1 - 0.39 11.3 2.9 4.7 7.8 0.1 2.9 2 1 1 3 3 3 0 MerR, DNA binding RabGAP-TBC PF00566.18 VBB27281.1 - 7.5e-50 169.6 1.2 1.5e-49 168.6 1.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 VBB27281.1 - 1.6e-26 93.8 0.3 1.3e-25 90.9 0.3 2.5 1 1 0 1 1 1 1 Kinesin protein PID PF00640.23 VBB27281.1 - 3.5e-06 27.1 1.0 5.1e-05 23.3 0.1 2.9 2 1 1 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 VBB27281.1 - 0.00081 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotyrosine-binding domain UPF0242 PF06785.11 VBB27281.1 - 0.023 14.8 26.5 0.75 9.9 1.0 3.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 VBB27281.1 - 0.18 12.5 18.2 0.079 13.6 1.1 3.7 2 1 1 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 VBB27281.1 - 0.18 12.0 24.6 0.015 15.5 13.0 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 VBB27281.1 - 0.47 10.5 23.7 0.041 13.9 1.6 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1090 PF06476.12 VBB27281.1 - 0.49 10.5 5.8 2.8 8.1 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) APG6_N PF17675.1 VBB27281.1 - 0.95 10.0 26.5 6.2 7.3 8.6 3.6 1 1 1 3 3 3 0 Apg6 coiled-coil region bZIP_1 PF00170.21 VBB27281.1 - 3.3 7.9 15.7 0.94 9.6 0.2 4.2 1 1 3 4 4 4 0 bZIP transcription factor DivIC PF04977.15 VBB27281.1 - 6.4 6.6 13.3 28 4.6 0.1 3.8 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 VBB27281.1 - 6.6 7.2 20.0 1.5 9.3 1.6 3.8 2 1 1 3 3 3 0 Cell division protein ZapB ERM PF00769.19 VBB27281.1 - 8.8 6.1 24.9 1e+02 2.5 25.2 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.21 VBB27282.1 - 5.2e-06 26.5 13.0 5.2e-06 26.5 13.0 2.5 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 VBB27282.1 - 0.00091 19.5 2.9 0.0017 18.6 1.4 2.3 2 0 0 2 2 1 1 TSC-22/dip/bun family PspA_IM30 PF04012.12 VBB27282.1 - 0.0025 17.4 0.7 0.0075 15.9 0.7 1.9 1 0 0 1 1 1 1 PspA/IM30 family DUF2730 PF10805.8 VBB27282.1 - 0.2 11.8 1.8 3.4 7.8 0.5 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Yuri_gagarin PF15934.5 VBB27282.1 - 0.2 11.5 8.4 0.026 14.4 2.3 2.4 2 1 0 2 2 2 0 Yuri gagarin FAM76 PF16046.5 VBB27282.1 - 0.3 10.4 10.6 0.046 13.1 1.1 2.5 2 0 0 2 2 2 0 FAM76 protein TMF_DNA_bd PF12329.8 VBB27282.1 - 0.67 10.0 11.0 0.052 13.5 3.8 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 VBB27282.1 - 1.4 8.9 6.6 0.27 11.3 1.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Bap31_Bap29_C PF18035.1 VBB27282.1 - 1.5 8.9 4.2 60 3.8 2.5 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain GAS PF13851.6 VBB27282.1 - 5.5 6.3 16.1 0.13 11.6 5.7 2.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 VBB27282.1 - 7.3 7.3 8.3 0.31 11.7 0.2 2.9 4 0 0 4 4 3 0 SlyX NRBF2 PF08961.10 VBB27282.1 - 8.7 5.9 8.6 1.3 8.6 3.8 2.0 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator CALCOCO1 PF07888.11 VBB27283.1 - 2.2 7.0 50.3 0.052 12.4 12.4 2.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF16 PF01519.16 VBB27285.1 - 0.09 13.3 3.2 0.18 12.3 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 FAD_binding_2 PF00890.24 VBB27286.1 - 1.6e-90 304.2 0.8 2e-90 303.8 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 VBB27286.1 - 3.4e-12 46.6 1.7 1.7e-07 31.1 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 VBB27286.1 - 5.5e-11 42.5 1.8 3.5e-10 39.8 1.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 VBB27286.1 - 3e-08 33.2 2.9 2.5e-05 23.5 0.3 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 VBB27286.1 - 1.1e-07 31.4 1.7 2.9e-06 26.7 0.8 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 VBB27286.1 - 6.4e-07 28.4 0.7 7e-05 21.7 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 VBB27286.1 - 1e-05 25.7 0.2 3.4e-05 24.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 VBB27286.1 - 0.00016 21.1 0.3 0.076 12.3 0.1 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 VBB27286.1 - 0.002 17.4 0.1 0.0097 15.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 VBB27286.1 - 0.0077 15.5 0.2 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 VBB27286.1 - 0.012 14.8 0.7 0.021 14.1 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 VBB27286.1 - 0.02 15.4 1.5 0.77 10.4 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 VBB27286.1 - 0.023 13.7 0.8 0.052 12.6 0.8 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 VBB27286.1 - 0.023 14.7 0.3 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 VBB27286.1 - 0.05 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Thi4 family KH_1 PF00013.29 VBB27287.1 - 8.1e-57 188.9 13.3 7.9e-17 60.8 0.3 4.5 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 VBB27287.1 - 4.1e-21 74.2 2.4 4.1e-21 74.2 2.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1897) KH_2 PF07650.17 VBB27287.1 - 2.2e-14 53.0 1.5 0.00045 20.0 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 VBB27287.1 - 3.8e-07 29.9 3.7 0.19 11.6 0.1 3.6 3 0 0 3 3 3 3 KH domain LEA_6 PF10714.9 VBB27287.1 - 0.66 10.1 7.6 0.42 10.7 4.5 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein 18 Epimerase PF01370.21 VBB27288.1 - 7e-22 78.1 0.1 9.9e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 VBB27288.1 - 9.8e-18 64.1 0.0 1.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 VBB27288.1 - 7.4e-14 51.5 0.5 2e-13 50.1 0.4 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 VBB27288.1 - 2.3e-13 50.5 0.1 3.2e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 VBB27288.1 - 6.4e-12 45.5 0.1 8.5e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 VBB27288.1 - 6.3e-07 29.2 0.1 1.1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 VBB27288.1 - 4.1e-06 26.2 0.2 6.2e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 VBB27288.1 - 0.0032 17.0 0.6 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase INTS2 PF14750.6 VBB27288.1 - 0.0082 13.8 0.0 0.011 13.4 0.0 1.1 1 0 0 1 1 1 1 Integrator complex subunit 2 KR PF08659.10 VBB27288.1 - 0.1 12.5 0.2 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 KR domain Sep15_SelM PF08806.11 VBB27289.1 - 1.9e-24 85.6 0.1 4.2e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Sep15/SelM redox domain Pyr_redox_2 PF07992.14 VBB27290.1 - 3.4e-41 141.4 3.8 6.5e-18 65.0 0.0 3.3 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 VBB27290.1 - 3.5e-36 123.8 0.2 2e-35 121.4 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Longin PF13774.6 VBB27290.1 - 7.4e-20 70.8 0.1 1.9e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 VBB27290.1 - 8.9e-13 47.9 0.0 8.9e-13 47.9 0.0 2.0 2 0 0 2 2 1 1 Synaptobrevin Pyr_redox_3 PF13738.6 VBB27290.1 - 2.2e-11 43.6 1.4 2.3e-07 30.4 0.0 3.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 VBB27290.1 - 2.1e-09 37.8 1.5 2.3e-07 31.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 VBB27290.1 - 0.00024 20.6 0.8 0.00044 19.7 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 VBB27290.1 - 0.0034 16.5 1.3 0.24 10.4 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 VBB27290.1 - 0.0048 17.3 1.1 2.4 8.7 0.0 3.1 3 0 0 3 3 3 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 VBB27290.1 - 0.0051 16.1 0.0 1.5 8.1 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 VBB27290.1 - 0.084 11.9 3.1 0.42 9.6 1.8 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 VBB27290.1 - 0.1 11.3 0.1 0.38 9.4 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Sec20 PF03908.13 VBB27290.1 - 0.1 12.5 0.3 0.38 10.7 0.3 1.9 2 0 0 2 2 2 0 Sec20 ApbA PF02558.16 VBB27290.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 VBB27290.1 - 0.13 12.5 4.5 0.1 12.9 1.2 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 VBB27290.1 - 0.14 11.5 0.2 9.3 5.6 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 VBB27290.1 - 0.16 11.9 0.4 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Novirhabdo_Nv PF05554.11 VBB27292.1 - 0.0076 16.0 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Viral hemorrhagic septicemia virus non-virion protein BSD PF03909.17 VBB27295.1 - 2e-21 75.7 3.2 4.5e-16 58.6 0.1 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 VBB27295.1 - 6e-19 68.2 0.0 7.9e-17 61.4 0.0 2.5 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain RolB_RolC PF02027.17 VBB27295.1 - 0.31 10.7 1.7 3.7 7.2 1.3 2.4 1 1 0 1 1 1 0 RolB/RolC glucosidase family DUF5305 PF17231.2 VBB27296.1 - 0.016 14.7 0.1 0.018 14.4 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 VBB27296.1 - 0.029 14.3 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 Rifin Saf_2TM PF18303.1 VBB27296.1 - 0.034 13.7 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain TMEM154 PF15102.6 VBB27296.1 - 0.072 13.0 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family LapA_dom PF06305.11 VBB27296.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 VBB27296.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SIT PF15330.6 VBB27296.1 - 0.14 12.6 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT 4HB_MCP_1 PF12729.7 VBB27296.1 - 0.15 11.6 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction FeoB_associated PF12669.7 VBB27296.1 - 8.9 6.8 6.0 20 5.7 6.0 1.6 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PSI_integrin PF17205.3 VBB27297.1 - 3.5e-08 33.1 8.1 3.5e-08 33.1 8.1 2.9 2 0 0 2 2 2 1 Integrin plexin domain EGF_2 PF07974.13 VBB27297.1 - 1.1e-06 28.9 64.7 0.00026 21.3 17.1 6.8 6 1 1 7 7 7 3 EGF-like domain I-EGF_1 PF18372.1 VBB27297.1 - 9.8e-06 25.6 28.5 0.00013 21.9 9.7 6.8 7 1 0 7 7 7 4 Integrin beta epidermal growth factor like domain 1 T2SSB PF16537.5 VBB27297.1 - 0.21 11.2 0.0 0.54 9.9 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system protein B LRR_8 PF13855.6 VBB27298.1 - 1.8e-48 162.1 51.1 6.3e-13 48.3 0.3 6.6 3 2 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 VBB27298.1 - 2.3e-22 78.7 32.3 1.9e-06 28.1 2.0 7.6 6 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB27298.1 - 2.9e-20 72.5 2.0 2.5e-10 40.4 0.0 3.6 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB27298.1 - 3.4e-13 49.5 7.9 2.4e-05 23.9 2.4 4.0 1 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 VBB27298.1 - 1.4e-06 28.0 38.4 0.18 12.5 1.5 11.4 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.6 VBB27298.1 - 0.0043 17.0 26.1 19 5.7 0.1 9.0 9 0 0 9 9 9 2 Leucine Rich repeat Copine PF07002.16 VBB27299.1 - 1.1e-57 195.0 0.0 1.6e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 VBB27299.1 - 0.00032 21.0 0.0 0.00064 20.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 VBB27299.1 - 0.0073 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Methyltransf_11 PF08241.12 VBB27300.1 - 1.7e-10 41.4 0.0 4.2e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB27300.1 - 5.3e-08 33.5 0.1 5.4e-07 30.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB27300.1 - 3.3e-06 27.0 0.2 0.00029 20.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB27300.1 - 0.00016 22.4 0.1 0.0083 16.9 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB27300.1 - 0.00044 20.1 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 VBB27300.1 - 0.061 13.2 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Ribo_biogen_C PF04034.13 VBB27301.1 - 3.1e-49 165.9 0.0 4.2e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 VBB27301.1 - 3.4e-14 52.4 0.1 5.7e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Vpu PF00558.19 VBB27301.1 - 1.2 9.0 2.7 1.2 9.0 0.2 2.0 2 0 0 2 2 2 0 Vpu protein WD40 PF00400.32 VBB27302.1 - 9e-44 146.6 32.3 2.6e-07 31.2 1.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 VBB27302.1 - 3.5e-12 46.0 8.5 4.6e-12 45.6 5.5 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 VBB27302.1 - 7.4e-10 38.5 6.2 2.4e-09 36.8 6.2 2.0 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 VBB27302.1 - 2.8e-09 36.2 9.5 0.0076 14.9 0.9 4.3 2 1 1 4 4 4 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 VBB27302.1 - 1.4e-06 28.5 7.5 0.02 15.2 1.3 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 VBB27302.1 - 0.0034 17.2 2.2 0.0043 16.9 0.2 2.2 2 0 0 2 2 2 1 F-box HARP PF07443.13 VBB27302.1 - 0.089 12.4 0.0 10 5.8 0.0 3.4 3 0 0 3 3 3 0 HepA-related protein (HARP) Ge1_WD40 PF16529.5 VBB27302.1 - 0.099 11.6 7.5 3.4 6.5 0.2 3.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein UAA PF08449.11 VBB27303.1 - 7.2e-64 215.9 19.0 1.1e-63 215.3 19.0 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 VBB27303.1 - 0.00016 21.9 15.7 0.00016 21.9 15.7 2.9 2 2 1 3 3 3 1 EamA-like transporter family TPT PF03151.16 VBB27303.1 - 0.0043 16.5 6.4 0.0043 16.5 6.4 2.5 1 1 2 3 3 3 2 Triose-phosphate Transporter family PUNUT PF16913.5 VBB27303.1 - 0.12 11.5 16.5 0.035 13.3 5.5 2.1 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport TMEM234 PF10639.9 VBB27303.1 - 5.1 7.2 11.0 15 5.6 0.4 2.5 2 1 0 2 2 2 0 Putative transmembrane family 234 GDP_Man_Dehyd PF16363.5 VBB27304.1 - 1.8e-159 530.6 0.1 2e-159 530.4 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 VBB27304.1 - 7.6e-78 261.3 0.0 9.9e-78 260.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 VBB27304.1 - 1.1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 VBB27304.1 - 3.6e-06 26.3 0.0 6.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 VBB27304.1 - 0.044 13.3 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family Nuc_sug_transp PF04142.15 VBB27305.1 - 1.4e-102 343.1 20.9 1.9e-102 342.7 20.9 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PET PF06297.14 VBB27305.1 - 6.8e-20 71.2 0.0 1.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 VBB27305.1 - 6e-10 39.2 5.6 6e-10 39.2 5.6 3.4 3 0 0 3 3 3 1 LIM domain EamA PF00892.20 VBB27305.1 - 0.00068 19.8 6.4 0.00068 19.8 6.4 2.4 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.6 VBB27305.1 - 0.0025 17.4 1.5 0.0025 17.4 1.5 2.2 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter TMEM234 PF10639.9 VBB27305.1 - 0.83 9.7 6.4 0.079 13.0 1.3 1.9 2 0 0 2 2 2 0 Putative transmembrane family 234 IBR PF01485.21 VBB27306.1 - 2.5e-15 56.4 43.4 3.5e-11 43.2 15.5 4.8 6 1 0 6 6 6 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 VBB27306.1 - 0.0088 15.9 7.0 0.0088 15.9 7.0 5.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB27306.1 - 0.019 14.9 8.5 0.019 14.9 8.5 5.1 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB27306.1 - 0.026 14.8 8.0 0.026 14.8 8.0 5.5 3 1 1 4 4 4 0 Ring finger domain XRCC4 PF06632.12 VBB27307.1 - 0.011 14.6 7.6 0.015 14.1 7.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CDC45 PF02724.14 VBB27307.1 - 0.18 10.1 6.5 0.23 9.7 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Endonuc_Holl PF10107.9 VBB27307.1 - 3.4 7.5 7.5 14 5.5 0.2 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Presenilin PF01080.17 VBB27307.1 - 8.4 5.0 7.2 12 4.5 7.2 1.2 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 VBB27308.1 - 5.5e-07 30.2 1.0 1.2e-05 25.9 0.6 3.1 3 1 0 3 3 3 1 WD domain, G-beta repeat WD40 PF00400.32 VBB27309.1 - 3.5e-47 157.4 24.4 3.3e-09 37.2 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27309.1 - 2e-24 85.7 2.0 1.2e-06 28.7 0.1 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 VBB27309.1 - 2.6e-08 33.5 0.1 6e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 VBB27309.1 - 3.4e-07 29.9 0.3 0.063 12.6 0.0 3.8 2 1 2 4 4 4 2 WD40-like domain eIF2A PF08662.11 VBB27309.1 - 2.9e-06 27.3 0.9 0.0084 16.0 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 VBB27309.1 - 0.006 15.3 1.7 0.16 10.6 0.0 3.3 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 VBB27309.1 - 0.0087 15.0 0.3 4.7 6.1 0.0 3.5 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 VBB27309.1 - 0.024 14.6 0.0 0.3 11.1 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DNase_II PF03265.15 VBB27312.1 - 6.9e-97 324.6 2.7 7.8e-97 324.4 2.7 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II HCO3_cotransp PF00955.21 VBB27313.1 - 3e-161 537.7 13.8 1.3e-141 473.0 8.0 2.1 2 0 0 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 VBB27313.1 - 1.9e-35 123.0 0.2 3.5e-24 86.0 0.0 2.8 2 1 1 3 3 3 2 Band 3 cytoplasmic domain SH3_1 PF00018.28 VBB27315.1 - 5.8e-34 115.4 1.9 6.4e-16 57.7 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 VBB27315.1 - 2.4e-29 100.9 0.0 6.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain TTR-52 PF01060.23 VBB27315.1 - 6.3e-28 97.3 0.0 1.7e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Transthyretin-like family SH3_2 PF07653.17 VBB27315.1 - 4.2e-27 93.6 0.0 2.6e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 VBB27315.1 - 4.2e-26 90.9 0.1 8.4e-26 89.9 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 VBB27315.1 - 0.0032 17.7 0.2 0.025 14.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain DUF5093 PF17011.5 VBB27315.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) Mtc PF03820.17 VBB27316.1 - 2e-108 362.2 3.6 2.2e-108 362.0 3.6 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SAM_2 PF07647.17 VBB27317.1 - 8.5e-24 83.5 0.2 8.1e-09 35.5 0.0 3.9 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 VBB27317.1 - 1.1e-23 83.4 1.3 6.4e-10 39.3 0.1 4.3 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) GAS PF13851.6 VBB27317.1 - 0.061 12.7 107.5 0.072 12.4 15.9 7.3 2 1 5 7 7 7 0 Growth-arrest specific micro-tubule binding Chorein_N PF12624.7 VBB27318.1 - 4.1e-14 52.7 0.1 1.7e-13 50.7 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 VBB27318.1 - 1.1e-13 51.3 0.0 3.9e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 VBB27318.1 - 2.2e-07 30.8 0.0 6.7e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 VBB27318.1 - 0.0083 15.9 0.1 0.11 12.2 0.0 2.7 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ADIP PF11559.8 VBB27318.1 - 0.15 12.1 0.3 8 6.5 0.0 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HSL_N PF06350.12 VBB27319.1 - 2.7e-71 240.0 0.0 9e-71 238.3 0.0 1.8 2 0 0 2 2 2 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 VBB27319.1 - 2.7e-39 135.2 0.0 4.9e-27 95.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 VBB27319.1 - 1.1e-10 40.9 0.1 2.9e-10 39.6 0.1 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Syndecan PF01034.20 VBB27321.1 - 6.3e-29 99.7 0.0 1.2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 VBB27321.1 - 0.00048 20.3 0.1 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 Glycophorin A MGC-24 PF05283.11 VBB27321.1 - 0.04 14.4 0.2 0.12 12.8 0.2 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NEMP PF10225.9 VBB27321.1 - 0.087 12.5 0.5 0.13 11.9 0.5 1.2 1 0 0 1 1 1 0 NEMP family FeoB_associated PF12669.7 VBB27321.1 - 0.19 12.2 0.5 0.32 11.4 0.5 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein UNC45-central PF11701.8 VBB27322.1 - 3.5e-27 95.2 1.7 7.5e-26 90.9 0.1 3.3 4 0 0 4 4 3 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 VBB27322.1 - 2.9e-14 52.2 3.7 4.1e-06 26.4 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27322.1 - 2.2e-09 36.7 9.5 3e-05 23.8 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27322.1 - 3.7e-05 23.6 7.6 0.1 12.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB27322.1 - 4.2e-05 23.1 2.7 0.0036 16.9 0.2 3.2 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 VBB27322.1 - 0.00014 21.9 0.8 0.094 12.9 0.6 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB27322.1 - 0.00099 19.7 2.5 17 6.5 0.0 5.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB27322.1 - 0.0015 18.6 1.3 0.0037 17.3 0.2 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 VBB27322.1 - 0.0025 18.0 10.6 0.0089 16.3 0.0 5.2 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB27322.1 - 0.0045 17.6 3.5 0.74 10.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3361 PF11841.8 VBB27322.1 - 0.041 13.8 4.8 0.27 11.2 0.2 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF3361) TPR_17 PF13431.6 VBB27322.1 - 0.11 12.9 0.7 29 5.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M9_N PF08453.10 VBB27322.1 - 0.12 12.1 0.6 3.1 7.5 0.1 2.4 1 1 1 2 2 2 0 Peptidase family M9 N-terminal TPR_7 PF13176.6 VBB27322.1 - 0.16 12.1 1.4 2.4 8.4 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 VBB27322.1 - 0.38 11.5 7.8 1.9 9.3 0.4 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat V-ATPase_H_C PF11698.8 VBB27322.1 - 0.49 10.5 8.0 1 9.5 0.1 4.2 4 0 0 4 4 4 0 V-ATPase subunit H DUF4194 PF13835.6 VBB27322.1 - 4.7 6.9 6.5 4 7.1 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4194) TraC PF07820.12 VBB27322.1 - 4.7 7.6 5.9 5.1 7.5 0.7 3.2 3 0 0 3 3 3 0 TraC-like protein Lustrin_cystein PF14625.6 VBB27324.1 - 2.7e-76 251.7 246.8 5.6e-07 29.8 12.0 17.7 16 2 2 18 18 18 16 Lustrin, cysteine-rich repeated domain Kunitz_BPTI PF00014.23 VBB27324.1 - 2.8e-39 133.1 51.4 2.2e-14 53.4 7.5 5.3 5 0 0 5 5 5 3 Kunitz/Bovine pancreatic trypsin inhibitor domain EB PF01683.18 VBB27324.1 - 3.5e-06 27.2 24.3 1.6e-05 25.1 11.4 13.3 9 4 1 10 10 10 2 EB module cEGF PF12662.7 VBB27324.1 - 0.011 15.7 0.4 0.011 15.7 0.4 11.0 11 0 0 11 11 11 0 Complement Clr-like EGF-like IL17 PF06083.11 VBB27325.1 - 0.00032 21.1 1.2 0.00051 20.5 0.8 1.6 1 1 0 1 1 1 1 Interleukin-17 Elongin_A PF06881.11 VBB27325.1 - 0.084 13.4 2.4 0.19 12.3 2.2 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Spaetzle PF16077.5 VBB27325.1 - 0.22 12.1 6.6 0.2 12.2 4.6 1.9 1 1 1 2 2 2 0 Spaetzle DUF1657 PF07870.11 VBB27325.1 - 0.37 10.7 1.8 7.3 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) NT-C2 PF10358.9 VBB27326.1 - 2.9e-25 88.7 0.0 4.1e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-U1 PF06220.12 VBB27327.1 - 3.6e-07 29.8 0.1 6.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 VBB27327.1 - 8.9e-06 25.7 0.2 2.1e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 WW domain Death PF00531.22 VBB27328.1 - 7.3e-10 38.9 0.0 8.4e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Death domain DUF2152 PF10222.9 VBB27329.1 - 2.3e-149 498.5 0.1 3e-149 498.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Porin_3 PF01459.22 VBB27330.1 - 1.4e-46 159.1 0.0 2.2e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic porin SPARC_Ca_bdg PF10591.9 VBB27330.1 - 3.3e-35 120.8 1.7 3.3e-35 120.8 1.7 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region FOLN PF09289.10 VBB27330.1 - 5.4e-09 36.1 5.2 5.4e-09 36.1 5.2 2.2 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain Kazal_2 PF07648.15 VBB27330.1 - 2.7e-08 33.8 9.5 2.7e-08 33.8 9.5 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.32 VBB27330.1 - 0.031 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 VBB27330.1 - 0.042 13.3 0.5 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 EF hand Kazal_1 PF00050.21 VBB27330.1 - 0.55 10.3 10.8 1.5 8.9 8.2 2.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Innexin PF00876.18 VBB27331.1 - 7e-111 370.9 11.4 8.4e-111 370.7 11.4 1.0 1 0 0 1 1 1 1 Innexin PI-PLC-X PF00388.19 VBB27332.1 - 2.4e-49 166.7 0.0 4e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 VBB27332.1 - 5.9e-26 91.1 0.8 1.9e-25 89.5 0.0 2.3 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 VBB27332.1 - 2e-19 69.8 0.0 3.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.6 VBB27332.1 - 2.6e-09 36.8 1.0 8.3e-09 35.2 1.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_like PF09279.11 VBB27332.1 - 7.7e-08 32.7 0.0 2.5e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 VBB27332.1 - 6.9e-06 25.6 4.7 0.0037 17.1 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 VBB27332.1 - 1.2e-05 24.5 10.9 0.00019 20.7 0.1 4.3 4 0 0 4 4 4 2 EF hand GDPD PF03009.17 VBB27332.1 - 3.6e-05 23.6 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_5 PF13202.6 VBB27332.1 - 0.00034 20.0 0.3 0.00034 20.0 0.3 3.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 VBB27332.1 - 0.0096 15.8 7.5 0.064 13.1 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_7 PF13499.6 VBB27332.1 - 0.017 15.5 6.7 0.025 15.0 3.1 3.1 2 1 0 2 2 2 0 EF-hand domain pair DnaJ PF00226.31 VBB27333.1 - 1.5e-16 60.3 0.1 6e-16 58.3 0.1 2.2 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 VBB27333.1 - 7.2e-12 45.3 2.6 8.1e-07 29.1 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain RAC_head PF16717.5 VBB27333.1 - 9.4e-08 32.9 0.3 9.4e-08 32.9 0.3 3.5 3 1 0 3 3 3 1 Ribosome-associated complex head domain DUP PF00674.18 VBB27333.1 - 0.045 13.9 0.7 13 6.0 0.2 2.8 2 0 0 2 2 2 0 DUP family Acyl-CoA_dh_N PF02771.16 VBB27334.1 - 8.2e-08 32.9 0.0 1.7e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 VBB27334.1 - 0.00048 20.4 0.0 0.0012 19.0 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 VBB27335.1 - 2.7e-07 30.4 0.4 5.2e-07 29.5 0.4 1.5 1 0 0 1 1 1 1 Spo12 family PI_PP_I PF18363.1 VBB27336.1 - 0.0024 18.0 0.1 0.0024 18.0 0.1 2.5 3 0 0 3 3 3 1 Phosphoinositide phosphatase insertion domain Bap31_Bap29_C PF18035.1 VBB27336.1 - 0.022 14.8 3.3 0.022 14.8 3.3 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain INPP5B_PH PF16776.5 VBB27336.1 - 0.04 13.6 2.9 0.18 11.5 0.6 2.4 2 0 0 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Pox_A_type_inc PF04508.12 VBB27336.1 - 0.059 13.2 2.8 0.081 12.8 0.3 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2016 PF09436.10 VBB27336.1 - 0.11 12.4 0.1 7.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) MCC-bdg_PDZ PF10506.9 VBB27336.1 - 1.6 8.8 10.6 0.4 10.7 4.0 3.0 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APG6_N PF17675.1 VBB27336.1 - 2.9 8.4 36.0 0.5 10.9 10.0 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region NDUFB11 PF17250.2 VBB27336.1 - 4.7 7.9 6.0 0.9 10.2 0.9 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Phage_GPO PF05929.11 VBB27336.1 - 6 6.4 18.8 2.9 7.4 1.3 2.7 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 VBB27336.1 - 6.2 5.3 20.1 0.6 8.7 3.7 2.6 2 1 1 3 3 3 0 Flagellar Assembly Protein A DUF2759 PF10958.8 VBB27337.1 - 0.018 14.7 1.3 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) YjeF_N PF03853.15 VBB27338.1 - 2e-39 135.2 0.0 2.6e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pkinase PF00069.25 VBB27339.1 - 1.3e-63 214.9 0.0 1.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27339.1 - 5.1e-24 85.0 0.0 7.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB27339.1 - 3.9e-05 23.1 0.0 0.00049 19.5 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 VBB27339.1 - 0.00061 19.2 0.1 0.00093 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB27339.1 - 0.00074 19.5 0.0 0.0046 16.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 VBB27339.1 - 0.018 14.6 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 VBB27339.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 VBB27340.1 - 6e-63 212.7 0.2 1.1e-62 211.8 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27340.1 - 7.6e-17 61.4 0.0 3.5e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB27340.1 - 3.6e-06 27.1 0.0 2e-05 24.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB27340.1 - 0.0031 17.1 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 VBB27340.1 - 0.0049 15.7 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB27340.1 - 0.0049 16.2 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 VBB27340.1 - 0.044 13.4 0.2 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aminotran_5 PF00266.19 VBB27341.1 - 1.7e-75 254.3 0.1 7.1e-50 170.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 VBB27341.1 - 0.0049 16.2 0.5 0.011 15.1 0.5 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 VBB27341.1 - 0.0079 15.6 0.6 0.017 14.5 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 VBB27341.1 - 0.017 13.8 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Tub PF01167.18 VBB27342.1 - 2.3e-28 99.6 0.6 3.1e-25 89.3 0.1 2.6 2 1 0 2 2 2 2 Tub family ANAPC4_WD40 PF12894.7 VBB27342.1 - 3.4e-09 36.9 2.6 0.11 12.8 0.1 5.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3527 PF12043.8 VBB27342.1 - 0.00094 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) WD40 PF00400.32 VBB27342.1 - 0.0011 19.7 8.2 1.2 10.1 0.1 5.1 5 0 0 5 5 4 1 WD domain, G-beta repeat NPV_P10 PF05531.12 VBB27342.1 - 0.043 14.3 1.6 0.52 10.8 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 VBB27342.1 - 0.049 13.9 4.4 1.5 9.2 0.7 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BLI1 PF17324.2 VBB27342.1 - 0.083 13.6 0.4 0.22 12.2 0.4 1.7 1 0 0 1 1 1 0 BLOC-1 interactor 1 KxDL PF10241.9 VBB27342.1 - 0.15 12.4 3.7 0.98 9.7 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Spc7 PF08317.11 VBB27342.1 - 0.16 10.8 2.5 0.17 10.7 1.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein TBK1_CCD1 PF18394.1 VBB27342.1 - 0.17 11.4 3.4 0.088 12.4 0.7 1.9 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 FlaC_arch PF05377.11 VBB27342.1 - 0.18 12.2 0.4 0.65 10.4 0.4 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 VBB27342.1 - 0.23 11.5 5.1 2.1 8.4 0.5 3.0 2 1 1 3 3 3 0 Laminin Domain II Med9 PF07544.13 VBB27342.1 - 0.24 11.5 0.8 0.6 10.2 0.8 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.20 VBB27342.1 - 0.73 9.8 2.7 11 6.0 0.3 2.7 3 0 0 3 3 3 0 Prefoldin subunit SCAMP PF04144.13 VBB27343.1 - 4.2e-55 186.7 23.2 5.1e-55 186.5 23.2 1.1 1 0 0 1 1 1 1 SCAMP family Spectrin PF00435.21 VBB27344.1 - 0.00017 22.0 2.2 0.00017 22.0 2.2 4.1 4 1 0 4 4 4 1 Spectrin repeat PI_PP_I PF18363.1 VBB27344.1 - 0.0011 19.0 1.4 0.028 14.6 0.2 3.1 2 1 0 2 2 2 1 Phosphoinositide phosphatase insertion domain OKR_DC_1_N PF03709.15 VBB27344.1 - 0.0073 16.6 0.1 0.06 13.6 0.0 2.4 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, N-terminal domain ApoL PF05461.11 VBB27344.1 - 0.39 10.0 3.5 0.59 9.4 0.8 2.2 2 0 0 2 2 2 0 Apolipoprotein L His_Phos_2 PF00328.22 VBB27344.1 - 0.79 9.0 5.7 0.16 11.2 0.7 2.2 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) KELK PF15796.5 VBB27344.1 - 1.6 9.2 12.2 0.66 10.5 0.5 4.0 4 0 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF643 PF04867.12 VBB27344.1 - 5 7.8 7.8 3.9 8.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF643) CENP-H PF05837.12 VBB27344.1 - 7.4 7.0 9.9 2.4 8.6 0.4 3.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) HSBP1 PF06825.12 VBB27344.1 - 9.8 6.1 7.9 16 5.5 0.0 4.0 5 0 0 5 5 5 0 Heat shock factor binding protein 1 Histone PF00125.24 VBB27345.1 - 3.9e-14 53.1 0.0 5.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 VBB27345.1 - 3.3e-09 36.3 0.0 3.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 VBB27345.1 - 3.9e-05 23.8 0.5 0.0001 22.5 0.0 2.0 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TrbC PF04956.13 VBB27346.1 - 0.083 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family TFIID_20kDa PF03847.13 VBB27348.1 - 2.9e-22 78.9 0.1 4.8e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 VBB27348.1 - 0.0034 17.4 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 VBB27348.1 - 0.025 14.9 0.4 0.074 13.4 0.0 2.0 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB27348.1 - 0.08 13.2 2.3 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_2 PF07719.17 VBB27349.1 - 1.3e-16 59.2 8.6 5.7e-05 22.9 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27349.1 - 4.6e-16 57.6 2.0 0.00012 22.0 0.1 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB27349.1 - 2.9e-14 52.5 1.1 0.019 15.8 0.0 7.3 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB27349.1 - 6.5e-14 51.1 4.3 0.0002 21.0 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB27349.1 - 4e-11 43.3 0.2 0.0004 20.8 0.4 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB27349.1 - 4.7e-11 42.3 4.1 8.3e-05 22.7 0.2 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB27349.1 - 9.9e-10 38.6 3.9 0.08 13.2 0.2 5.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB27349.1 - 7.1e-09 36.2 0.0 4.4e-05 24.0 0.2 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27349.1 - 6.8e-07 29.4 7.6 0.21 11.8 0.0 4.1 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 VBB27349.1 - 3.4e-06 26.7 0.5 0.24 11.5 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB27349.1 - 1.6e-05 24.3 1.3 0.083 12.1 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 VBB27349.1 - 0.00021 21.3 0.0 0.66 10.4 0.0 4.2 4 0 0 4 4 3 1 PPR repeat TPR_11 PF13414.6 VBB27349.1 - 0.00047 19.8 8.7 0.0011 18.6 1.2 4.3 4 1 3 7 7 7 1 TPR repeat TPR_9 PF13371.6 VBB27349.1 - 0.011 15.9 0.4 2 8.6 0.2 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 VBB27349.1 - 0.026 13.5 0.2 0.11 11.5 0.1 1.9 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 VBB27349.1 - 0.062 14.0 0.5 34 5.3 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 VBB27349.1 - 0.096 12.6 4.0 0.49 10.3 0.1 3.5 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_10 PF13374.6 VBB27349.1 - 1 9.3 4.8 8.3 6.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TBP PF00352.21 VBB27350.1 - 3.2e-65 216.1 0.1 5e-32 109.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 VBB27350.1 - 9.2e-05 22.5 0.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Ribosomal_L4 PF00573.22 VBB27351.1 - 4.7e-38 130.8 0.0 6.8e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CBF PF03914.17 VBB27351.1 - 5.2e-20 72.2 0.1 1.2e-19 71.0 0.1 1.6 1 0 0 1 1 1 1 CBF/Mak21 family ANAPC4_WD40 PF12894.7 VBB27352.1 - 1.3e-05 25.4 0.0 0.009 16.3 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB27352.1 - 0.0044 16.4 0.0 0.02 14.2 0.0 1.9 1 1 1 2 2 2 1 WD40-like domain zf-HIT PF04438.16 VBB27352.1 - 0.0068 16.2 13.0 0.016 15.0 13.0 1.7 1 0 0 1 1 1 1 HIT zinc finger BBS2_Mid PF14783.6 VBB27352.1 - 0.028 14.4 0.0 0.25 11.4 0.0 2.6 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_L21p PF00829.21 VBB27353.1 - 8.2e-16 58.1 0.1 6.4e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Collagen PF01391.18 VBB27354.1 - 5e-22 77.4 97.5 5.7e-09 35.6 37.1 4.3 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB27354.1 - 2.4e-13 49.9 0.5 3.6e-13 49.3 0.5 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain PAN_1 PF00024.26 VBB27355.1 - 5.6e-19 67.9 22.3 1.4e-07 31.4 3.3 3.2 3 0 0 3 3 3 3 PAN domain BTB PF00651.31 VBB27356.1 - 8.4e-29 100.0 0.4 3e-28 98.2 0.1 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 VBB27356.1 - 0.15 12.2 0.1 8.5 6.5 0.0 3.0 2 1 0 3 3 3 0 BTB And C-terminal Kelch PAN_1 PF00024.26 VBB27357.1 - 0.00099 19.0 1.1 0.0022 17.9 1.1 1.6 1 0 0 1 1 1 1 PAN domain Peripla_BP_2 PF01497.18 VBB27357.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Spin-Ssty PF02513.17 VBB27358.1 - 0.06 13.1 0.2 0.81 9.5 0.0 2.6 2 0 0 2 2 2 0 Spin/Ssty Family Trehalase PF01204.18 VBB27359.1 - 2e-144 482.3 0.1 2.3e-144 482.0 0.1 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 VBB27359.1 - 0.00024 20.0 0.1 0.26 10.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain GDE_C PF06202.14 VBB27359.1 - 0.00034 19.7 0.0 0.00054 19.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase HS1_rep PF02218.15 VBB27360.1 - 1.2e-125 409.4 69.6 1.8e-19 69.7 3.1 8.8 8 0 0 8 8 8 7 Repeat in HS1/Cortactin SH3_1 PF00018.28 VBB27360.1 - 2.8e-16 58.9 0.4 6.1e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB27360.1 - 1.6e-15 56.7 0.3 3.7e-15 55.5 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain Abhydrolase_1 PF00561.20 VBB27360.1 - 4.2e-12 46.3 0.0 6.3e-11 42.4 0.0 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB27360.1 - 1.1e-09 38.0 0.0 1.1e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SH3_2 PF07653.17 VBB27360.1 - 4.9e-09 35.7 0.0 1.6e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Abhydrolase_6 PF12697.7 VBB27360.1 - 2.2e-08 35.0 0.0 4.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 VBB27360.1 - 9.9e-07 29.1 1.2 0.0011 19.1 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain TMEM210 PF15195.6 VBB27360.1 - 6.7e-05 23.3 1.9 27 5.2 0.0 5.8 2 1 4 6 6 6 0 TMEM210 family rRNA_proc-arch PF13234.6 VBB27361.1 - 1.2e-69 235.2 3.9 2.8e-69 234.1 3.9 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 VBB27361.1 - 1.2e-52 177.9 0.2 2.4e-52 176.9 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 VBB27361.1 - 2e-19 70.0 0.0 7.8e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB27361.1 - 1.8e-05 25.1 0.0 0.00016 22.0 0.0 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain UPF0449 PF15136.6 VBB27361.1 - 0.023 15.2 2.1 0.023 15.2 2.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Rotamase PF00639.21 VBB27361.1 - 0.069 14.1 1.2 0.28 12.2 1.2 2.0 1 0 0 1 1 1 0 PPIC-type PPIASE domain HalX PF08663.10 VBB27361.1 - 0.65 10.4 6.2 31 5.0 1.8 3.7 3 0 0 3 3 3 0 HalX domain Pkinase PF00069.25 VBB27362.1 - 4.7e-26 91.7 0.2 5.7e-26 91.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27362.1 - 4.6e-17 62.2 0.2 5.7e-17 61.9 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB27362.1 - 0.00084 19.3 0.0 0.2 11.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 VBB27362.1 - 0.0067 15.2 0.0 0.019 13.8 0.0 1.5 1 1 0 2 2 2 1 Fungal protein kinase HTH_27 PF13463.6 VBB27362.1 - 0.021 15.3 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain Kdo PF06293.14 VBB27362.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Enolase_C PF00113.22 VBB27363.1 - 1.9e-145 483.7 0.2 2.6e-145 483.2 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 VBB27363.1 - 2e-58 196.2 0.0 3.6e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 VBB27363.1 - 2.9e-05 23.7 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 VBB27363.1 - 3.9e-05 22.9 0.6 0.0002 20.6 0.4 2.0 1 1 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Spc7 PF08317.11 VBB27364.1 - 0.017 14.0 43.4 0.52 9.1 17.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.13 VBB27364.1 - 0.9 9.7 7.9 0.55 10.4 0.8 3.0 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Bacillus_HBL PF05791.11 VBB27364.1 - 2.9 7.7 21.6 0.5 10.2 8.9 2.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.6 VBB27364.1 - 4.6 5.8 37.1 0.68 8.5 20.1 2.1 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.10 VBB27364.1 - 8 6.6 31.6 8.1 6.6 8.3 3.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family PIGA PF08288.12 VBB27365.1 - 1.2e-37 128.4 0.6 1.2e-37 128.4 0.6 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 VBB27365.1 - 1e-27 97.2 0.3 3.5e-27 95.5 0.4 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 VBB27365.1 - 1.1e-24 86.9 0.0 2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 VBB27365.1 - 4.1e-22 79.0 0.0 8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 VBB27365.1 - 2.8e-11 44.1 0.0 5.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 VBB27365.1 - 0.0026 17.8 0.1 0.0048 16.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like PDR_assoc PF08370.11 VBB27365.1 - 0.0073 16.0 0.8 0.016 14.9 0.8 1.5 1 0 0 1 1 1 1 Plant PDR ABC transporter associated Glyco_trans_1_2 PF13524.6 VBB27365.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 efThoc1 PF11957.8 VBB27366.1 - 8.1e-101 338.1 13.3 1.2e-100 337.5 13.3 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 VBB27366.1 - 0.00043 20.4 0.1 0.0014 18.7 0.1 2.0 1 0 0 1 1 1 1 Death domain Sulfotransfer_1 PF00685.27 VBB27368.1 - 6.1e-23 81.6 0.5 8e-23 81.3 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 VBB27368.1 - 8.6e-08 32.8 0.1 1.5e-05 25.5 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family PI-PLC-X PF00388.19 VBB27369.1 - 1.6e-56 189.9 0.0 4.8e-56 188.4 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 VBB27369.1 - 4.8e-38 130.0 0.1 4.8e-38 130.0 0.1 2.8 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF4093 PF13331.6 VBB27369.1 - 0.054 13.9 1.4 3 8.3 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4093) EF-hand_like PF09279.11 VBB27369.1 - 0.068 13.7 0.0 0.41 11.2 0.0 2.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like FixO PF02433.15 VBB27369.1 - 0.085 12.3 0.2 0.31 10.5 0.2 2.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO HATPase_c_5 PF14501.6 VBB27369.1 - 0.22 11.5 2.6 17 5.4 0.7 3.2 2 0 0 2 2 2 0 GHKL domain Homeodomain PF00046.29 VBB27370.1 - 3.2e-19 68.5 8.1 6e-19 67.7 8.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27370.1 - 0.0091 15.9 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Pepsin-I3 PF06394.13 VBB27372.1 - 3.9e-05 23.7 0.1 6.1e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain DUF3662 PF12401.8 VBB27372.1 - 0.029 14.7 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Pox_RNA_pol PF03293.14 VBB27372.1 - 0.042 13.6 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit ANAPC4_WD40 PF12894.7 VBB27373.1 - 0.00049 20.3 0.0 1.1 9.6 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Hyd_WA PF06462.12 VBB27373.1 - 0.016 15.2 11.0 0.058 13.4 0.7 3.9 3 1 0 3 3 3 0 Propeller WD40 PF00400.32 VBB27373.1 - 0.036 14.9 3.6 0.42 11.6 0.1 4.1 3 0 0 3 3 3 0 WD domain, G-beta repeat WBP-1 PF11669.8 VBB27374.1 - 0.0026 18.3 2.8 0.0038 17.8 2.8 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 Comm PF15957.5 VBB27374.1 - 0.076 13.4 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 Commissureless MAP17 PF15807.5 VBB27374.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM154 PF15102.6 VBB27374.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family OPA3 PF07047.12 VBB27374.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Sigma_reg_N PF13800.6 VBB27374.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal LapA_dom PF06305.11 VBB27374.1 - 0.15 11.9 0.4 0.27 11.1 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 VBB27374.1 - 0.18 12.0 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMIE PF16038.5 VBB27374.1 - 0.28 11.0 2.5 0.5 10.2 2.5 1.4 1 0 0 1 1 1 0 TMIE protein PAS_9 PF13426.7 VBB27375.1 - 3.3e-09 36.9 0.0 4.9e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 PAS domain PAS PF00989.25 VBB27375.1 - 0.00022 21.2 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 VBB27375.1 - 0.003 17.5 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 VBB27375.1 - 0.0042 17.4 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold ArsC PF03960.15 VBB27375.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 ArsC family PAS_4 PF08448.10 VBB27375.1 - 0.14 12.5 0.0 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 PAS fold Y_phosphatase PF00102.27 VBB27376.1 - 4.9e-38 131.0 0.0 6.3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 VBB27377.1 - 1.2e-64 218.2 0.4 1.4e-64 217.9 0.4 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EF-hand_1 PF00036.32 VBB27379.1 - 8.1e-38 125.2 9.9 1e-09 37.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB27379.1 - 1.4e-32 112.0 2.1 2e-15 57.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB27379.1 - 7.8e-30 102.5 9.3 6.7e-13 48.3 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 VBB27379.1 - 4.5e-27 91.6 5.6 1.7e-09 36.9 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 VBB27379.1 - 1.7e-24 84.2 7.3 9.5e-07 28.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 VBB27379.1 - 2.9e-13 49.9 0.1 3.3e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 VBB27379.1 - 1.9e-06 27.7 0.3 0.075 13.0 0.1 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 VBB27379.1 - 2.7e-06 27.7 0.0 0.029 14.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 VBB27379.1 - 3.3e-05 23.8 0.0 0.055 13.5 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 VBB27379.1 - 4.5e-05 24.3 0.0 0.087 13.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 VBB27379.1 - 0.00023 21.2 0.2 0.0013 18.7 0.0 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 VBB27379.1 - 0.00091 19.7 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) Dockerin_1 PF00404.18 VBB27379.1 - 0.0012 19.0 4.8 0.15 12.3 0.5 3.0 1 1 1 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 VBB27379.1 - 0.0039 17.1 0.3 0.74 9.7 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 VBB27379.1 - 0.0042 17.4 0.6 2 8.8 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 Helo_like_N PF17111.5 VBB27379.1 - 0.013 14.9 0.2 0.032 13.6 0.1 1.7 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF1103 PF06513.11 VBB27379.1 - 0.014 15.0 2.6 0.018 14.7 2.6 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Poly_export PF02563.16 VBB27379.1 - 0.025 14.8 0.0 0.79 10.0 0.0 2.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 VBB27379.1 - 0.032 14.4 0.2 0.56 10.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 VBB27379.1 - 0.048 12.8 0.1 2.6 7.2 0.0 2.2 1 1 1 2 2 2 0 Cache domain TerB PF05099.13 VBB27379.1 - 0.077 13.0 0.2 0.74 9.8 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_2 PF13623.6 VBB27379.1 - 0.092 12.6 0.3 5.5 6.8 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 VBB27379.1 - 0.13 12.6 0.1 13 6.2 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF2757 PF10955.8 VBB27379.1 - 0.13 12.5 2.2 3.9 7.8 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2757) Fe_hyd_lg_C PF02906.14 VBB27379.1 - 0.14 11.8 0.3 0.48 10.1 0.3 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 VBB27379.1 - 0.16 12.0 0.0 11 6.1 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Laminin_I PF06008.14 VBB27380.1 - 0.00026 20.8 1.2 0.00035 20.3 1.2 1.1 1 0 0 1 1 1 1 Laminin Domain I DivIVA PF05103.13 VBB27380.1 - 0.021 14.9 2.2 0.13 12.4 2.2 2.0 1 1 0 1 1 1 0 DivIVA protein TRAF_BIRC3_bd PF16673.5 VBB27380.1 - 0.033 14.0 1.5 0.29 11.0 0.3 2.2 1 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 VBB27380.1 - 0.078 13.0 0.8 0.42 10.6 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 VBB27380.1 - 0.24 10.3 5.7 0.42 9.4 5.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Asparaginase PF00710.20 VBB27381.1 - 3.3e-42 144.2 0.0 5.5e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_4 PF13637.6 VBB27381.1 - 1.1e-27 96.0 9.3 2.4e-11 43.9 0.5 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Asparaginase_C PF17763.1 VBB27381.1 - 9.1e-22 77.4 0.1 2.6e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 VBB27381.1 - 3.1e-21 75.7 4.3 8.7e-12 45.5 0.8 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB27381.1 - 1e-14 53.2 2.2 0.00011 22.3 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 VBB27381.1 - 4.4e-14 52.4 4.0 4.7e-09 36.3 0.7 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB27381.1 - 2.1e-13 50.1 5.7 5e-05 23.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat DUF4796 PF16044.5 VBB27381.1 - 0.0055 16.3 0.1 2.1 7.9 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4796) Mic1 PF07035.12 VBB27382.1 - 3.6e-36 124.3 3.6 8.4e-36 123.0 3.6 1.6 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like ANAPC4_WD40 PF12894.7 VBB27382.1 - 0.0028 17.9 0.0 0.063 13.6 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Frigida PF07899.11 VBB27382.1 - 0.034 13.4 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Frigida-like protein Shugoshin_C PF07557.11 VBB27383.1 - 0.0001 22.0 0.2 0.00025 20.7 0.2 1.7 1 0 0 1 1 1 1 Shugoshin C terminus Transglut_i_TM PF14400.6 VBB27383.1 - 0.011 15.8 0.5 0.011 15.8 0.5 1.9 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices DivIC PF04977.15 VBB27383.1 - 0.026 14.3 4.3 0.041 13.7 1.9 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF3453 PF11935.8 VBB27384.1 - 8.1e-56 189.2 0.8 1.4e-54 185.1 0.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 VBB27384.1 - 1.9e-36 125.9 0.0 5.9e-36 124.3 0.0 2.0 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF1800 PF08811.11 VBB27384.1 - 0.084 11.9 0.0 0.76 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1800) IZUMO PF15005.6 VBB27384.1 - 2.1 8.9 7.2 0.16 12.5 0.5 2.6 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated G_glu_transpept PF01019.21 VBB27385.1 - 1e-159 532.6 0.0 1.2e-159 532.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Kunitz_BPTI PF00014.23 VBB27387.1 - 2.2e-152 495.3 173.9 3.2e-18 65.7 9.7 12.0 12 0 0 12 12 12 11 Kunitz/Bovine pancreatic trypsin inhibitor domain Mcm10 PF09332.11 VBB27387.1 - 3.2e-60 204.5 25.5 3.2e-60 204.5 25.5 7.4 7 1 1 8 8 8 1 Mcm10 replication factor Lustrin_cystein PF14625.6 VBB27387.1 - 9.6e-20 70.7 49.9 4.4e-06 27.0 4.3 5.4 4 0 0 4 4 4 4 Lustrin, cysteine-rich repeated domain Thyroglobulin_1 PF00086.18 VBB27387.1 - 1.1e-12 47.4 0.9 4.5e-12 45.4 0.9 2.2 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat zf-primase PF09329.11 VBB27387.1 - 6.8e-07 29.0 1.6 4.9e-06 26.2 1.6 2.7 1 0 0 1 1 1 1 Primase zinc finger zinc_ribbon_13 PF09855.9 VBB27387.1 - 0.034 14.3 3.5 5 7.4 1.1 3.2 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Peptidase_C1 PF00112.23 VBB27388.1 - 3.3e-74 249.6 0.0 5e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 VBB27388.1 - 1.4e-08 35.1 1.8 1.4e-08 35.1 1.8 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 VBB27388.1 - 1.1e-05 24.5 0.1 0.0019 17.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family GCV_T PF01571.21 VBB27389.1 - 1.2e-14 54.4 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain CS PF04969.16 VBB27390.1 - 2.6e-12 47.6 0.7 6.3e-12 46.3 0.7 1.7 1 0 0 1 1 1 1 CS domain SGS PF05002.15 VBB27390.1 - 2.7e-06 27.4 2.5 7e-06 26.1 2.5 1.7 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.11 VBB27390.1 - 0.00016 21.9 2.5 0.00019 21.7 0.2 2.2 2 0 0 2 2 2 1 Siah interacting protein, N terminal SMG1 PF15785.5 VBB27390.1 - 0.0021 16.6 0.8 0.0023 16.4 0.8 1.1 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 MerR-DNA-bind PF09278.11 VBB27390.1 - 0.061 13.9 0.4 0.14 12.7 0.2 1.7 2 0 0 2 2 2 0 MerR, DNA binding Kinesin PF00225.23 VBB27391.1 - 7.7e-102 340.6 0.0 2.1e-101 339.2 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 VBB27391.1 - 6.5e-21 74.8 0.7 1.3e-20 73.8 0.1 1.9 2 0 0 2 2 2 1 Microtubule binding WD40_alt PF14077.6 VBB27391.1 - 0.027 14.3 0.9 4.2 7.3 0.3 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2326 PF10088.9 VBB27391.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) DEAD PF00270.29 VBB27391.1 - 0.19 11.5 3.7 6.4 6.5 0.2 3.3 3 1 0 3 3 3 0 DEAD/DEAH box helicase Acyl-CoA_dh_2 PF08028.11 VBB27391.1 - 0.27 11.5 2.0 0.42 10.9 0.1 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2981 PF11200.8 VBB27391.1 - 0.32 10.7 2.3 0.65 9.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) ResIII PF04851.15 VBB27391.1 - 0.41 10.6 4.6 0.62 10.0 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Occludin_ELL PF07303.13 VBB27391.1 - 6.8 7.5 8.3 0.28 11.9 0.3 2.9 3 1 0 3 3 3 0 Occludin homology domain Pox_A_type_inc PF04508.12 VBB27391.1 - 8.3 6.4 7.8 0.88 9.5 0.5 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Nitroreductase PF00881.24 VBB27392.1 - 7.5e-22 78.2 0.0 1.3e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 VBB27392.1 - 2.7e-07 30.4 0.0 0.0049 16.5 0.0 3.2 2 2 1 3 3 3 3 Putative TM nitroreductase BLIP PF07467.11 VBB27392.1 - 0.021 15.4 0.0 0.074 13.7 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) PBS_linker_poly PF00427.21 VBB27392.1 - 0.022 14.8 0.1 1.6 8.8 0.0 2.5 2 1 0 2 2 2 0 Phycobilisome Linker polypeptide LapA_dom PF06305.11 VBB27392.1 - 0.34 10.8 1.6 0.51 10.2 0.1 2.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DnaJ PF00226.31 VBB27393.1 - 1.2e-25 89.4 1.2 2e-25 88.7 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_1 PF00561.20 VBB27395.1 - 5e-14 52.6 0.0 1.4e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 VBB27395.1 - 5.4e-14 53.3 0.0 4.9e-11 43.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 VBB27395.1 - 4e-05 23.0 0.0 0.00027 20.3 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 VBB27395.1 - 0.047 13.8 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein L51_S25_CI-B8 PF05047.16 VBB27396.1 - 0.0032 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AIMP2_LysRS_bd PF16780.5 VBB27396.1 - 0.029 14.1 0.2 0.064 13.0 0.2 1.5 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain Ion_trans PF00520.31 VBB27397.1 - 2.2e-218 721.4 81.7 3.7e-70 235.9 9.4 6.1 4 2 1 5 5 5 5 Ion transport protein Ca_chan_IQ PF08763.11 VBB27397.1 - 5.6e-29 100.2 0.0 1.2e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 VBB27397.1 - 4.1e-28 96.9 0.1 1e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated CAC1F_C PF16885.5 VBB27397.1 - 0.0079 15.9 10.5 0.052 13.2 0.0 3.4 4 0 0 4 4 4 2 Voltage-gated calcium channel subunit alpha, C-term Sigma70_ner PF04546.13 VBB27397.1 - 0.36 10.7 9.9 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Ribonucleas_3_3 PF14622.6 VBB27398.1 - 0.04 14.1 0.1 0.1 12.8 0.1 1.8 1 1 0 1 1 1 0 Ribonuclease-III-like Cyclin_N PF00134.23 VBB27399.1 - 9.5e-30 103.0 0.5 2.4e-29 101.6 0.5 1.8 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 VBB27399.1 - 5.4e-17 62.0 0.1 9.7e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain YvbH_ext PF11724.8 VBB27399.1 - 0.13 12.6 0.1 5.8 7.3 0.0 2.9 2 0 0 2 2 2 0 YvbH-like oligomerisation region SH3_1 PF00018.28 VBB27400.1 - 7.3e-36 121.5 1.0 4.7e-11 42.1 0.0 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 VBB27400.1 - 2.2e-32 110.7 0.4 1.8e-09 37.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 VBB27400.1 - 1.5e-22 79.1 0.2 1.3e-09 37.5 0.0 4.8 5 1 0 5 5 5 3 Variant SH3 domain Bromo_TP PF07524.13 VBB27401.1 - 2.7e-20 72.2 0.5 9.6e-20 70.4 0.1 2.2 3 0 0 3 3 3 1 Bromodomain associated TAF8_C PF10406.9 VBB27401.1 - 4.1e-14 52.9 0.2 2.4e-13 50.4 0.2 2.4 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term AAA_33 PF13671.6 VBB27401.1 - 5.9e-10 39.5 0.0 2.1e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Bromo_TP_like PF17027.5 VBB27401.1 - 0.00011 22.3 0.0 0.0005 20.2 0.0 2.2 1 0 0 1 1 1 1 Histone-fold protein AAA_24 PF13479.6 VBB27401.1 - 0.0011 18.7 0.0 0.0032 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Smr PF01713.21 VBB27401.1 - 0.0017 18.7 0.0 0.0059 16.9 0.0 2.0 1 0 0 1 1 1 1 Smr domain Zeta_toxin PF06414.12 VBB27401.1 - 0.03 13.6 0.2 0.09 12.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 VBB27401.1 - 0.076 13.6 0.0 0.79 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 VBB27401.1 - 0.081 13.3 2.5 36 4.8 0.0 4.2 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) TAF4 PF05236.14 VBB27401.1 - 0.093 12.5 3.1 0.095 12.4 0.3 2.4 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family zf-MIZ PF02891.20 VBB27401.1 - 0.12 12.1 0.3 0.35 10.6 0.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger AAA_22 PF13401.6 VBB27401.1 - 0.13 12.5 0.1 3.3 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF1771 PF08590.10 VBB27401.1 - 0.16 12.3 5.3 0.49 10.8 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) CBFD_NFYB_HMF PF00808.23 VBB27401.1 - 0.2 12.0 2.3 0.45 10.8 0.2 2.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA_17 PF13207.6 VBB27401.1 - 0.23 11.9 0.9 8.7 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sds3 PF08598.11 VBB27402.1 - 1.6e-10 41.3 18.6 3e-10 40.5 17.2 1.7 1 1 0 1 1 1 1 Sds3-like DUF45 PF01863.17 VBB27402.1 - 0.042 13.9 4.2 0.063 13.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 RdRP_1 PF00680.20 VBB27402.1 - 0.17 10.4 2.5 0.2 10.1 2.5 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Focal_AT PF03623.13 VBB27402.1 - 0.47 10.5 4.2 0.9 9.5 4.2 1.4 1 1 0 1 1 1 0 Focal adhesion targeting region Sec3_C_2 PF15278.6 VBB27402.1 - 3.1 8.2 6.1 2.8 8.4 0.5 2.4 1 1 1 2 2 2 0 Sec3 exocyst complex subunit FapA PF03961.13 VBB27402.1 - 4.4 5.8 9.4 5.9 5.4 9.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PP2C_C PF07830.13 VBB27402.1 - 6.4 7.3 10.7 0.52 10.8 3.3 2.7 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain ATP-synt_ab PF00006.25 VBB27403.1 - 4.1e-68 229.2 0.0 5.8e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 VBB27403.1 - 8.7e-09 35.8 0.3 3.5e-06 27.4 0.1 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain Adenylate_cycl PF01295.18 VBB27403.1 - 0.2 10.3 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I RRM_1 PF00076.22 VBB27404.1 - 9.4e-21 73.4 0.6 1.4e-05 24.8 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 VBB27404.1 - 0.087 13.1 0.0 9.1 6.5 0.0 2.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter YfhD PF14151.6 VBB27405.1 - 0.081 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 YfhD-like protein CARD PF00619.21 VBB27406.1 - 4.5e-10 39.4 0.5 8.3e-10 38.6 0.5 1.5 1 1 1 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 VBB27406.1 - 1.9e-06 27.8 0.2 2.3e-06 27.5 0.2 1.1 1 0 0 1 1 1 1 Caspase recruitment domain XLF PF09302.11 VBB27406.1 - 0.03 14.5 0.2 0.063 13.4 0.1 1.5 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FKBP_C PF00254.28 VBB27408.1 - 2.2e-23 82.4 0.1 6.5e-14 52.0 0.0 3.0 2 1 1 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 VBB27408.1 - 8.1e-13 47.6 9.8 5.1e-05 22.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27408.1 - 7.5e-11 41.3 6.9 5.3e-05 23.0 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27408.1 - 4e-08 32.8 4.1 0.00017 21.5 0.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB27408.1 - 1.8e-06 28.1 5.8 0.0097 16.2 0.8 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB27408.1 - 2.4e-06 27.1 1.9 0.11 12.2 1.7 3.6 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 VBB27408.1 - 1.7e-05 25.1 4.6 0.00077 19.9 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB27408.1 - 5.5e-05 23.7 1.5 0.038 14.6 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB27408.1 - 0.00053 20.1 1.7 0.013 15.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB27408.1 - 0.00078 19.7 2.6 0.031 14.6 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB27408.1 - 0.011 16.2 4.7 0.015 15.8 2.9 2.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 VBB27408.1 - 0.023 15.5 3.0 0.23 12.4 0.8 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 VBB27408.1 - 0.028 14.4 0.6 2.4 8.4 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27408.1 - 0.072 13.3 2.6 0.14 12.4 2.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 I-set PF07679.16 VBB27410.1 - 5.1e-111 363.0 0.0 3.2e-22 78.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB27410.1 - 1.4e-70 233.9 0.0 3.2e-11 43.7 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 VBB27410.1 - 1.2e-34 118.4 0.0 6.1e-06 26.5 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 VBB27410.1 - 7.2e-28 96.6 0.0 8.7e-05 22.6 0.0 6.7 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 VBB27410.1 - 3.9e-15 56.0 0.3 0.022 14.9 0.0 7.6 6 3 0 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB27410.1 - 2.4e-09 37.1 0.0 7.3 6.7 0.0 6.5 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Spectrin PF00435.21 VBB27410.1 - 1.2e-07 32.2 7.0 8.6e-07 29.4 1.7 9.0 5 2 5 10 10 8 4 Spectrin repeat Receptor_2B4 PF11465.8 VBB27410.1 - 1.5e-06 28.3 0.1 0.036 14.3 0.0 3.9 4 0 0 4 4 3 2 Natural killer cell receptor 2B4 Ig_6 PF18452.1 VBB27410.1 - 3.3e-05 23.4 0.0 0.01 15.4 0.0 3.9 5 0 0 5 5 5 1 Immunoglobulin domain Ig_5 PF16681.5 VBB27410.1 - 0.00026 21.3 0.0 2.1 8.8 0.0 5.1 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 VBB27410.1 - 0.0047 17.3 0.0 5.1 7.5 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Porin_OmpG_1_2 PF16946.5 VBB27410.1 - 0.016 14.5 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 OMPG-porin 1 family Ig_C17orf99 PF17736.1 VBB27410.1 - 0.089 12.8 0.2 5.7 7.1 0.1 3.7 4 0 0 4 4 4 0 C17orf99 Ig domain Herpes_gE PF02480.16 VBB27410.1 - 0.12 11.1 0.0 2.6 6.7 0.0 2.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E DUF4198 PF10670.9 VBB27410.1 - 0.13 12.6 0.1 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) Raco_middle PF17651.1 VBB27410.1 - 0.2 11.3 3.1 3.2 7.4 1.4 3.3 2 0 0 2 2 2 0 RACo middle region SNAPc19 PF15497.6 VBB27411.1 - 0.056 13.9 0.0 0.093 13.2 0.0 1.3 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 HutP PF09021.11 VBB27412.1 - 0.14 12.5 0.3 0.37 11.1 0.1 1.7 2 0 0 2 2 2 0 HutP IPU_b_solenoid PF18783.1 VBB27414.1 - 1.6 8.8 7.9 1.8 8.6 0.3 3.0 3 0 0 3 3 3 0 Isopullulanase beta-solenoid repeat tRNA_int_endo PF01974.17 VBB27415.1 - 2.6e-20 72.3 0.2 4.9e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 VBB27415.1 - 8.3e-08 31.8 0.0 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Proteasome PF00227.26 VBB27416.1 - 7.4e-55 185.4 0.3 9e-55 185.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 VBB27416.1 - 6.7e-14 51.3 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sec2p PF06428.11 VBB27416.1 - 0.064 13.2 0.3 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Hormone_recep PF00104.30 VBB27417.1 - 3.1e-18 66.1 0.0 5.8e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 VBB27417.1 - 9.2e-11 42.1 1.8 1.8e-10 41.1 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Collagen PF01391.18 VBB27418.1 - 8.6e-26 89.5 75.6 1.5e-10 40.6 33.8 3.8 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Homeodomain PF00046.29 VBB27419.1 - 1.1e-19 70.1 3.1 2.7e-19 68.8 3.1 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27419.1 - 0.063 13.2 0.1 0.27 11.1 0.1 2.2 1 0 0 1 1 1 0 Homeobox KN domain Methyltransf_8 PF05148.15 VBB27420.1 - 4.4e-87 291.5 1.3 8.3e-87 290.6 0.2 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase NOG1_N PF17835.1 VBB27420.1 - 5.6e-50 169.4 3.1 5.6e-50 169.4 3.1 2.6 2 0 0 2 2 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 VBB27420.1 - 3.3e-25 87.6 0.2 8e-25 86.4 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 VBB27420.1 - 6.1e-22 77.4 1.6 1.4e-21 76.2 1.6 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 VBB27420.1 - 2.1e-16 60.0 0.0 6.7e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_11 PF08241.12 VBB27420.1 - 2e-08 34.8 0.9 1.9e-07 31.6 0.0 3.2 3 1 0 3 3 2 1 Methyltransferase domain FeoB_N PF02421.18 VBB27420.1 - 1.2e-07 31.4 0.2 4.5e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Methyltransf_25 PF13649.6 VBB27420.1 - 2e-06 28.4 0.1 0.00079 20.1 0.1 3.9 2 1 0 2 2 2 1 Methyltransferase domain RsgA_GTPase PF03193.16 VBB27420.1 - 0.00031 20.7 0.1 0.27 11.1 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 VBB27420.1 - 0.0014 18.0 0.3 0.011 15.1 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.23 VBB27420.1 - 0.0023 18.0 1.9 3.5 7.7 0.0 3.8 4 0 0 4 4 4 2 Dynamin family Methyltransf_12 PF08242.12 VBB27420.1 - 0.028 15.1 0.6 8.6 7.2 0.0 4.0 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 VBB27420.1 - 0.037 13.8 4.5 0.58 9.9 0.3 3.4 2 2 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.6 VBB27420.1 - 0.058 13.7 0.2 3 8.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain MTS PF05175.14 VBB27420.1 - 0.1 12.2 0.4 2.6 7.6 0.1 2.6 1 1 1 2 2 2 0 Methyltransferase small domain AAA_16 PF13191.6 VBB27420.1 - 0.14 12.6 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Homeodomain PF00046.29 VBB27421.1 - 7.8e-21 73.7 3.1 1.4e-20 72.8 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27421.1 - 0.009 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Methyltransf_8 PF05148.15 VBB27422.1 - 4.4e-87 291.5 1.3 8.3e-87 290.6 0.2 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase NOG1_N PF17835.1 VBB27422.1 - 5.6e-50 169.4 3.1 5.6e-50 169.4 3.1 2.6 2 0 0 2 2 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 VBB27422.1 - 3.3e-25 87.6 0.2 8e-25 86.4 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 VBB27422.1 - 6.1e-22 77.4 1.6 1.4e-21 76.2 1.6 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 VBB27422.1 - 2.1e-16 60.0 0.0 6.7e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_11 PF08241.12 VBB27422.1 - 2e-08 34.8 0.9 1.9e-07 31.6 0.0 3.2 3 1 0 3 3 2 1 Methyltransferase domain FeoB_N PF02421.18 VBB27422.1 - 1.2e-07 31.4 0.2 4.5e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Methyltransf_25 PF13649.6 VBB27422.1 - 2e-06 28.4 0.1 0.00079 20.1 0.1 3.9 2 1 0 2 2 2 1 Methyltransferase domain RsgA_GTPase PF03193.16 VBB27422.1 - 0.00031 20.7 0.1 0.27 11.1 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 VBB27422.1 - 0.0014 18.0 0.3 0.011 15.1 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.23 VBB27422.1 - 0.0023 18.0 1.9 3.5 7.7 0.0 3.8 4 0 0 4 4 4 2 Dynamin family Methyltransf_12 PF08242.12 VBB27422.1 - 0.028 15.1 0.6 8.6 7.2 0.0 4.0 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 VBB27422.1 - 0.037 13.8 4.5 0.58 9.9 0.3 3.4 2 2 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.6 VBB27422.1 - 0.058 13.7 0.2 3 8.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain MTS PF05175.14 VBB27422.1 - 0.1 12.2 0.4 2.6 7.6 0.1 2.6 1 1 1 2 2 2 0 Methyltransferase small domain AAA_16 PF13191.6 VBB27422.1 - 0.14 12.6 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Homeodomain PF00046.29 VBB27423.1 - 4.7e-21 74.4 6.4 1.2e-20 73.1 6.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27423.1 - 0.022 14.7 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_ner PF04546.13 VBB27423.1 - 0.13 12.1 3.8 0.22 11.4 3.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 VBB27423.1 - 0.15 11.7 8.3 0.2 11.3 6.9 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 VBB27423.1 - 0.46 8.7 9.9 0.73 8.0 9.9 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 VBB27423.1 - 0.88 8.8 14.9 1.5 8.1 14.9 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 VBB27423.1 - 1.8 7.7 4.9 3.1 6.9 4.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RCC1 PF00415.18 VBB27424.1 - 7.8e-18 64.8 0.0 1.3e-05 25.7 0.0 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB27424.1 - 0.0036 17.1 0.4 6 6.8 0.0 3.4 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 VBB27424.1 - 0.0055 16.9 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 VBB27424.1 - 0.029 15.0 0.0 0.067 13.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) APP_E2 PF12925.7 VBB27426.1 - 8e-65 218.1 20.2 1.4e-64 217.4 20.2 1.3 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 VBB27426.1 - 1.5e-34 118.3 0.9 3.8e-34 117.1 0.1 2.2 2 0 0 2 2 1 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 VBB27426.1 - 2.7e-21 76.0 2.6 7.6e-21 74.6 2.6 1.8 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 VBB27426.1 - 5.1e-16 58.9 0.0 1.9e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus YlqD PF11068.8 VBB27426.1 - 0.18 12.2 10.1 0.41 11.0 10.1 1.6 1 0 0 1 1 1 0 YlqD protein DUF1140 PF06600.11 VBB27426.1 - 0.49 10.9 6.7 1.5 9.3 6.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) OmpH PF03938.14 VBB27426.1 - 1.1 9.6 14.7 3 8.2 14.7 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tho2 PF11262.8 VBB27426.1 - 2.3 7.3 10.3 5.1 6.2 10.3 1.6 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SDA1 PF05285.12 VBB27426.1 - 2.5 7.5 36.5 4.5 6.6 10.3 2.3 2 0 0 2 2 2 0 SDA1 CTD_bind PF04818.13 VBB27426.1 - 3.7 8.4 5.7 19 6.1 3.2 2.6 1 1 1 2 2 2 0 RNA polymerase II-binding domain. LAP1C PF05609.12 VBB27426.1 - 5.7 5.9 23.6 3.5 6.6 15.2 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RA PF00788.23 VBB27427.1 - 3.1e-31 107.9 0.1 6.5e-17 61.9 0.0 2.8 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 VBB27427.1 - 8e-25 87.1 0.2 2.1e-24 85.7 0.2 1.8 1 0 0 1 1 1 1 DIL domain PDZ PF00595.24 VBB27427.1 - 1.5e-14 54.1 1.3 4.2e-14 52.7 1.3 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB27427.1 - 2.8e-08 33.5 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB27427.1 - 0.00012 22.3 0.2 0.00098 19.4 0.1 2.4 2 0 0 2 2 2 1 PDZ domain FHA PF00498.26 VBB27427.1 - 0.00014 22.1 0.1 0.00048 20.4 0.1 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 VBB27427.1 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain IL1_propep PF02394.16 VBB27427.1 - 2.3 9.2 5.1 1.4 9.8 0.7 3.0 3 1 0 3 3 3 0 Interleukin-1 propeptide zf-C2H2 PF00096.26 VBB27428.1 - 1.7e-50 166.7 183.1 9.4e-05 22.7 1.8 24.3 24 0 0 24 24 24 20 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB27428.1 - 1.4e-43 143.8 183.4 0.0052 17.5 0.3 24.9 25 0 0 25 25 25 20 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB27428.1 - 1.3e-16 60.1 165.5 1.8e-06 28.1 0.2 22.8 25 1 0 25 25 24 9 Zinc-finger double domain zf-met PF12874.7 VBB27428.1 - 9.1e-08 32.2 130.5 0.39 11.2 0.1 21.7 22 0 0 22 22 22 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB27428.1 - 0.0095 16.2 120.3 0.064 13.6 0.1 20.0 23 0 0 23 23 22 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 VBB27428.1 - 0.012 15.4 0.3 0.012 15.4 0.3 6.6 7 1 1 8 8 8 0 GAGA factor zf-C2H2_11 PF16622.5 VBB27428.1 - 0.013 15.2 1.2 0.013 15.2 1.2 17.5 20 0 0 20 20 19 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 VBB27428.1 - 0.042 13.7 0.1 0.042 13.7 0.1 11.6 13 3 1 14 14 13 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 VBB27428.1 - 0.1 13.0 0.0 0.1 13.0 0.0 15.2 10 5 8 18 18 18 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 VBB27428.1 - 0.89 10.2 93.7 0.027 15.2 9.8 13.9 7 4 5 12 12 12 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 VBB27428.1 - 1.8 8.9 14.6 41 4.5 0.3 7.3 7 2 0 7 7 7 0 BolA-like protein Katanin_con80 PF13925.6 VBB27428.1 - 6.4 6.8 8.8 6.9 6.7 0.0 4.5 4 0 0 4 4 4 0 con80 domain of Katanin zf-C3HC4_3 PF13920.6 VBB27429.1 - 2.4e-10 40.1 31.1 4.6e-09 36.0 13.5 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB27429.1 - 0.00032 20.5 8.3 0.00032 20.5 8.3 3.4 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 VBB27429.1 - 0.0015 18.8 9.9 0.0015 18.8 9.9 3.0 3 0 0 3 3 3 1 Ring finger domain HLH PF00010.26 VBB27430.1 - 1.7e-08 34.3 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pyridoxal_deC PF00282.19 VBB27431.1 - 6e-118 393.8 0.0 8.4e-118 393.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SNARE_assoc PF09335.11 VBB27431.1 - 2.8e-07 31.0 0.2 8.8e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 SNARE associated Golgi protein Aminotran_5 PF00266.19 VBB27431.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 VBB27431.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Merozoite_SPAM PF07133.11 VBB27431.1 - 0.23 11.5 0.4 0.36 10.8 0.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Sdh5 PF03937.16 VBB27433.1 - 4e-11 42.7 0.0 7.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TM2 PF05154.16 VBB27433.1 - 6.7e-11 42.4 9.8 1.2e-10 41.5 9.8 1.4 1 0 0 1 1 1 1 TM2 domain MMR_HSR1_Xtn PF16897.5 VBB27434.1 - 4.9e-43 145.5 2.3 8.1e-43 144.8 1.2 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain CREPT PF16566.5 VBB27434.1 - 9.9e-42 142.6 3.4 2.3e-41 141.4 3.4 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour TGS PF02824.21 VBB27434.1 - 5.9e-22 77.5 0.0 1.7e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 VBB27434.1 - 2.6e-20 72.6 0.0 7.4e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase CTD_bind PF04818.13 VBB27434.1 - 4.9e-13 49.7 1.9 2.5e-12 47.4 0.1 3.0 3 0 0 3 3 2 1 RNA polymerase II-binding domain. FeoB_N PF02421.18 VBB27434.1 - 9.8e-10 38.2 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 VBB27434.1 - 0.00036 20.6 0.3 0.32 11.0 0.0 2.8 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 VBB27434.1 - 0.078 11.9 0.1 0.22 10.5 0.1 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 VBB27434.1 - 0.18 12.1 0.2 0.44 10.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain Guanylin PF02058.15 VBB27434.1 - 0.2 12.2 0.8 0.96 10.0 0.2 2.4 2 0 0 2 2 2 0 Guanylin precursor GTP_EFTU PF00009.27 VBB27434.1 - 0.28 10.7 1.6 7.8 6.0 0.1 3.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF2312 PF10073.9 VBB27434.1 - 8 6.2 9.6 3.2 7.5 0.7 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DNA_repr_REX1B PF14966.6 VBB27435.1 - 0.0066 17.1 3.8 0.0094 16.6 3.4 1.5 1 1 0 1 1 1 1 DNA repair REX1-B Galactosyl_T PF01762.21 VBB27436.1 - 4.4e-21 75.6 0.0 5.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase DSPc PF00782.20 VBB27437.1 - 1.2e-31 109.3 0.0 1.6e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB27437.1 - 0.0034 17.0 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 VBB27437.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Toxin_TOLIP PF00087.21 VBB27438.1 - 6.4e-05 23.1 11.1 9.1e-05 22.6 11.1 1.3 1 0 0 1 1 1 1 Snake toxin and toxin-like protein EXS PF03124.14 VBB27439.1 - 7.8e-95 318.0 25.5 7.8e-95 318.0 25.5 1.8 2 0 0 2 2 2 1 EXS family SPX PF03105.19 VBB27439.1 - 9.4e-30 104.8 18.8 1.6e-14 54.6 3.2 3.2 1 1 2 3 3 3 3 SPX domain SH3_1 PF00018.28 VBB27441.1 - 1.2e-05 24.9 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB27441.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB27441.1 - 0.0015 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.20 VBB27442.1 - 2.1e-28 99.8 6.7 2.1e-28 99.8 6.7 4.6 4 2 1 5 5 5 1 RhoGEF domain Spectrin PF00435.21 VBB27442.1 - 1e-17 64.5 52.3 8.6e-07 29.4 1.1 9.5 8 1 1 9 9 9 5 Spectrin repeat CRAL_TRIO PF00650.20 VBB27442.1 - 3.6e-07 30.0 0.0 1.4e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 VBB27442.1 - 0.00011 22.4 0.0 0.00037 20.7 0.0 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4054 PF13262.6 VBB27442.1 - 0.0013 18.8 1.4 0.071 13.1 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4054) Myc-LZ PF02344.15 VBB27442.1 - 0.12 12.5 3.0 0.45 10.7 1.1 3.0 2 0 0 2 2 2 0 Myc leucine zipper domain NAD_binding_9 PF13454.6 VBB27442.1 - 0.21 11.5 4.6 1.6 8.7 0.1 3.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding DUF2277 PF10041.9 VBB27442.1 - 0.28 11.5 1.5 57 4.1 0.0 3.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DUF4061 PF13270.6 VBB27442.1 - 0.98 9.8 4.9 1.6 9.1 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) PCMT PF01135.19 VBB27443.1 - 3.5e-23 82.5 0.0 1.5e-22 80.4 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 VBB27443.1 - 5.7e-05 22.9 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain SOCS_box PF07525.16 VBB27443.1 - 0.0057 17.0 0.3 2.9 8.3 0.2 2.5 2 0 0 2 2 2 2 SOCS box PID PF00640.23 VBB27444.1 - 2.1e-40 138.0 0.2 5.9e-40 136.5 0.2 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 VBB27444.1 - 4.2e-27 94.3 6.0 8.9e-13 48.4 0.2 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 VBB27444.1 - 3.8e-13 49.1 1.5 1.2e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB27444.1 - 0.0021 18.4 0.9 0.044 14.1 0.0 3.0 2 1 1 3 3 3 1 PDZ domain NRho PF16733.5 VBB27444.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Rhomboid N-terminal domain PRIMA1 PF16101.5 VBB27444.1 - 0.06 13.4 12.9 0.16 12.0 12.9 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Dicty_REP PF05086.12 VBB27444.1 - 0.98 7.3 15.3 1.7 6.5 15.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 VBB27444.1 - 1.9 7.0 11.1 2.8 6.5 11.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BTB_2 PF02214.22 VBB27446.1 - 7.3e-20 71.1 0.0 2e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Pro_Al_protease PF02983.14 VBB27446.1 - 0.09 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain RNase_PH PF01138.21 VBB27447.1 - 3.2e-06 27.7 2.4 1.2e-05 25.9 2.4 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 EF-hand_7 PF13499.6 VBB27448.1 - 4.2e-26 91.2 4.5 1e-11 45.1 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 VBB27448.1 - 1.4e-25 86.9 11.7 1.3e-05 24.4 0.1 5.4 5 1 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 VBB27448.1 - 7.4e-23 80.2 3.4 1.3e-12 47.4 0.0 3.8 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 VBB27448.1 - 2.1e-20 70.8 4.7 6.3e-05 22.6 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 VBB27448.1 - 1.8e-18 65.1 8.0 0.00011 21.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 VBB27448.1 - 0.0039 17.5 0.1 3.7 7.9 0.0 2.9 2 1 0 3 3 3 2 EF-hand domain GUN4 PF05419.12 VBB27448.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 GUN4-like SPARC_Ca_bdg PF10591.9 VBB27448.1 - 0.14 12.5 0.7 4.5 7.6 0.2 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 VBB27448.1 - 0.24 11.4 2.0 13 5.7 0.3 3.3 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 VBB27448.1 - 0.4 10.9 0.1 0.4 10.9 0.1 3.2 4 1 0 4 4 4 0 Dockerin type I domain Sec1 PF00995.23 VBB27449.1 - 3.4e-111 373.3 0.4 4.1e-111 373.0 0.4 1.1 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.20 VBB27449.1 - 0.049 14.1 0.1 2.9 8.4 0.0 2.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Collagen PF01391.18 VBB27451.1 - 8.1e-22 76.7 91.9 1e-10 41.2 30.2 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) His_Phos_1 PF00300.22 VBB27452.1 - 8.4e-25 87.6 0.0 2e-12 47.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ly-6_related PF06579.12 VBB27453.1 - 1.3e-24 86.8 5.3 2.4e-17 63.3 1.5 2.1 1 1 1 2 2 2 2 Caenorhabditis elegans ly-6-related protein TUDOR PF00567.24 VBB27454.1 - 9.9e-14 51.4 0.1 1.4e-10 41.2 0.0 3.0 2 1 0 2 2 2 2 Tudor domain ApeC PF16977.5 VBB27454.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of apextrin TRAP-gamma PF07074.12 VBB27455.1 - 1.8e-78 262.0 6.3 2.5e-78 261.5 6.3 1.2 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) HLH PF00010.26 VBB27455.1 - 2.3e-16 59.5 0.7 2.3e-16 59.5 0.7 2.5 4 0 0 4 4 4 1 Helix-loop-helix DNA-binding domain Ribosomal_L7Ae PF01248.26 VBB27456.1 - 5.1e-27 93.5 0.1 6.6e-27 93.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 VBB27456.1 - 0.00023 21.3 0.1 0.00026 21.1 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 VBB27456.1 - 0.0005 19.9 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain FlaC_arch PF05377.11 VBB27456.1 - 0.049 14.0 0.3 0.1 13.0 0.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) NTP_transferase PF00483.23 VBB27457.1 - 1.8e-13 50.7 0.0 5.1e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 VBB27457.1 - 3.8e-08 33.9 0.0 6.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 VBB27457.1 - 9.4e-06 25.2 1.3 0.016 15.0 0.2 3.0 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Steroid_dh PF02544.16 VBB27457.1 - 0.0021 18.1 1.1 0.048 13.6 1.1 2.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Hexapep_2 PF14602.6 VBB27457.1 - 0.0036 17.0 0.6 0.017 14.9 0.1 2.2 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 VBB27457.1 - 0.026 13.5 0.8 0.054 12.4 0.8 1.5 1 0 0 1 1 1 0 L-fucokinase zf-nanos PF05741.13 VBB27458.1 - 8.3e-16 58.0 4.4 4.3e-09 36.5 0.2 2.3 2 0 0 2 2 2 2 Nanos RNA binding domain Zn_ribbon_2 PF12674.7 VBB27458.1 - 0.00025 21.6 1.8 0.004 17.8 0.2 2.3 2 0 0 2 2 2 1 Putative zinc ribbon domain CpXC PF14353.6 VBB27458.1 - 0.027 14.5 0.5 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 CpXC protein VPS13 PF16908.5 VBB27460.1 - 3.3e-67 226.8 14.4 5.4e-64 216.2 7.9 4.5 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 VBB27460.1 - 1e-59 201.3 0.3 1e-59 201.3 0.3 3.1 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 VBB27460.1 - 7.9e-51 172.7 28.7 7.2e-47 159.8 0.4 6.7 6 2 1 7 7 7 3 Repeating coiled region of VPS13 Chorein_N PF12624.7 VBB27460.1 - 6.4e-34 116.5 0.9 4.3e-33 113.9 0.1 3.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 VBB27460.1 - 1.8e-27 96.5 0.1 1.4e-26 93.5 0.0 2.5 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 VBB27460.1 - 5.1e-07 29.9 0.0 2.2e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain HECT PF00632.25 VBB27461.1 - 3.5e-94 315.8 0.1 4.6e-94 315.3 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 VBB27461.1 - 7.5e-45 150.7 26.8 6.2e-13 48.6 0.6 5.0 5 0 0 5 5 5 4 WW domain C2 PF00168.30 VBB27461.1 - 9.5e-13 48.3 0.1 2e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 C2 domain DHHC PF01529.20 VBB27462.1 - 1e-36 126.0 3.8 1e-36 126.0 3.8 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Peptidase_S8 PF00082.22 VBB27463.1 - 1.8e-55 188.3 2.7 6.4e-55 186.5 1.3 2.0 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 VBB27463.1 - 1.2e-27 95.7 0.3 3.7e-27 94.2 0.2 1.9 2 0 0 2 2 2 1 Proprotein convertase P-domain TRAP_alpha PF03896.16 VBB27465.1 - 1e-58 198.8 3.9 3.9e-47 160.8 0.2 2.3 1 1 1 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit Sec34 PF04136.15 VBB27465.1 - 5.9e-39 133.3 4.2 1.5e-38 132.0 4.2 1.7 1 0 0 1 1 1 1 Sec34-like family FtsK_SpoIIIE PF01580.18 VBB27465.1 - 0.12 11.7 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family TACC_C PF05010.14 VBB27465.1 - 0.19 11.5 1.4 0.89 9.3 0.1 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cyclin_N PF00134.23 VBB27466.1 - 4.4e-11 42.6 0.6 9.5e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain RAI1 PF08652.11 VBB27466.1 - 0.082 13.1 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease DUF3603 PF12227.8 VBB27467.1 - 0.044 13.1 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) zf-C2H2 PF00096.26 VBB27467.1 - 0.074 13.5 1.4 0.23 12.0 1.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Myosin_head PF00063.21 VBB27468.1 - 7.5e-232 771.3 1.7 8.8e-232 771.1 1.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 VBB27468.1 - 0.00044 19.8 0.1 0.0014 18.2 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 VBB27468.1 - 0.012 16.0 0.3 0.071 13.5 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Myosin_N PF02736.19 VBB27468.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 VBB27468.1 - 0.07 13.4 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain STAR_dimer PF16544.5 VBB27469.1 - 2.5e-25 87.8 0.4 4.5e-25 87.0 0.4 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 VBB27469.1 - 7.4e-07 28.9 0.1 1.6e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 KH domain Trehalase PF01204.18 VBB27470.1 - 6.5e-152 506.9 2.0 7.5e-152 506.7 2.0 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 VBB27470.1 - 0.0015 17.5 0.7 0.0044 16.0 0.1 1.8 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Exo_endo_phos PF03372.23 VBB27471.1 - 5.9e-17 62.0 0.0 7.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 VBB27471.1 - 0.0013 18.5 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4834 PF16118.5 VBB27471.1 - 0.47 11.4 4.1 1 10.4 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) WH2 PF02205.20 VBB27472.1 - 0.00069 19.4 0.2 0.00069 19.4 0.2 2.4 3 0 0 3 3 3 1 WH2 motif YabA PF06156.13 VBB27472.1 - 0.3 11.7 1.4 0.87 10.3 0.1 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 VBB27472.1 - 0.49 9.7 7.6 2.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF737 PF05300.11 VBB27472.1 - 0.68 10.3 8.6 0.79 10.0 7.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) polyprenyl_synt PF00348.17 VBB27473.1 - 6.3e-61 205.7 0.0 7.5e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Lectin_leg-like PF03388.13 VBB27474.1 - 2.4e-75 252.8 0.0 3.4e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 VBB27474.1 - 9.4e-09 35.6 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial lectin OmpH PF03938.14 VBB27474.1 - 0.018 15.4 9.0 0.043 14.1 9.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 VBB27474.1 - 0.058 13.4 2.0 13 5.9 1.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMG_box PF00505.19 VBB27474.1 - 0.76 10.2 8.5 1.1 9.7 7.6 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box Occludin_ELL PF07303.13 VBB27474.1 - 1.5 9.6 10.9 0.5 11.1 7.4 2.0 2 0 0 2 2 2 0 Occludin homology domain Atg14 PF10186.9 VBB27474.1 - 2.6 7.0 6.8 0.64 9.0 3.4 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Noelin-1 PF12308.8 VBB27474.1 - 4.9 7.2 6.3 12 5.9 2.3 2.7 2 1 0 2 2 2 0 Neurogenesis glycoprotein BLOC1_2 PF10046.9 VBB27474.1 - 5 7.5 9.7 4 7.8 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 VBB27474.1 - 5.4 7.2 9.0 3.4 7.9 2.1 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase_Tyr PF07714.17 VBB27475.1 - 2e-86 289.5 0.0 3.5e-86 288.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB27475.1 - 1.7e-44 152.2 0.0 3.2e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Recep_L_domain PF01030.24 VBB27475.1 - 7.7e-22 77.5 0.2 1.8e-21 76.4 0.2 1.6 1 0 0 1 1 1 1 Receptor L domain Furin-like PF00757.20 VBB27475.1 - 1.5e-19 70.4 37.2 1.5e-19 70.4 37.2 1.9 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.21 VBB27475.1 - 1.1e-15 57.7 0.9 0.00073 19.8 0.0 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Sigma_reg_N PF13800.6 VBB27475.1 - 0.15 12.3 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PBC PF03792.13 VBB27476.1 - 6.8e-82 273.8 4.2 1.1e-81 273.1 4.2 1.3 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 VBB27476.1 - 4.7e-19 68.0 2.1 4.7e-19 68.0 2.1 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB27476.1 - 5.8e-16 58.1 1.2 2.6e-15 56.0 0.0 2.6 3 0 0 3 3 3 1 Homeobox KN domain YdaS_antitoxin PF15943.5 VBB27476.1 - 0.015 15.2 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Cor1 PF04803.12 VBB27476.1 - 0.029 14.6 1.0 0.029 14.6 1.0 2.9 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region NUC130_3NT PF08158.12 VBB27476.1 - 1.7 9.0 4.6 13 6.2 0.0 3.3 4 0 0 4 4 4 0 NUC130/3NT domain Phospholip_B PF04916.13 VBB27477.1 - 1e-171 572.2 2.5 1.7e-171 571.4 2.5 1.3 1 0 0 1 1 1 1 Phospholipase B ANAPC4_WD40 PF12894.7 VBB27477.1 - 0.0081 16.4 0.0 3.5 8.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M8 PF01457.16 VBB27478.1 - 3.7e-61 207.4 5.0 1e-36 126.7 0.0 2.7 1 1 1 2 2 2 2 Leishmanolysin Exo70 PF03081.15 VBB27478.1 - 0.0037 16.4 0.5 0.006 15.7 0.5 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Folliculin PF11704.8 VBB27478.1 - 0.14 12.1 0.1 0.38 10.6 0.1 1.8 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ARGLU PF15346.6 VBB27479.1 - 8.7e-23 80.9 29.9 8.7e-23 80.9 29.9 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 Exonuc_VII_L PF02601.15 VBB27479.1 - 2.9 7.4 19.7 1.2 8.7 17.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit ELMO_CED12 PF04727.13 VBB27480.1 - 5.9e-32 111.2 1.4 8e-31 107.5 1.4 2.5 1 1 0 1 1 1 1 ELMO/CED-12 family OTU PF02338.19 VBB27480.1 - 6.1e-20 72.0 0.0 1.9e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease DUF5432 PF17497.2 VBB27480.1 - 0.11 12.6 0.2 0.35 11.0 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5432) Allexi_40kDa PF05549.11 VBB27480.1 - 6.5 6.2 6.1 12 5.3 6.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein PC4 PF02229.16 VBB27481.1 - 4.9e-23 80.5 0.1 7.9e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) RRM_1 PF00076.22 VBB27482.1 - 4.4e-17 61.7 0.6 1.1e-16 60.4 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB27482.1 - 0.00018 21.1 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_6 PF13174.6 VBB27482.1 - 0.0012 19.4 0.9 0.0029 18.1 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat RRM_8 PF11835.8 VBB27482.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain wnt PF00110.19 VBB27483.1 - 1.9e-89 300.3 20.7 4.1e-89 299.2 20.7 1.5 1 1 0 1 1 1 1 wnt family WBP-1 PF11669.8 VBB27484.1 - 0.0059 17.2 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF4834 PF16118.5 VBB27484.1 - 0.011 16.7 0.1 0.011 16.7 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF4083 PF13314.6 VBB27484.1 - 0.11 12.4 0.9 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3742 PF12553.8 VBB27484.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) TMEMspv1-c74-12 PF11044.8 VBB27484.1 - 0.24 11.4 1.7 0.43 10.6 1.7 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Chitin_synth_2 PF03142.15 VBB27485.1 - 9.7e-26 90.5 10.9 1.7e-24 86.3 0.2 2.7 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 VBB27485.1 - 4.9e-13 49.4 3.5 4.9e-13 49.4 3.5 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 VBB27485.1 - 6.7e-06 26.2 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 VBB27485.1 - 0.0089 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DS PF01916.17 VBB27486.1 - 5.5e-125 416.4 0.0 6.4e-125 416.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SPRY PF00622.28 VBB27487.1 - 7.8e-16 58.3 0.6 3.2e-08 33.7 0.1 2.8 3 0 0 3 3 3 2 SPRY domain PHD PF00628.29 VBB27487.1 - 0.0046 16.8 5.9 0.0092 15.9 5.9 1.5 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 VBB27487.1 - 0.077 13.1 0.6 0.35 11.0 0.6 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger WAC_Acf1_DNA_bd PF10537.9 VBB27488.1 - 1.4e-29 102.6 0.0 1.4e-29 102.6 0.0 2.7 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.25 VBB27488.1 - 1.7e-24 85.7 1.8 7.2e-23 80.5 0.3 3.0 2 0 0 2 2 2 1 Bromodomain WSD PF15613.6 VBB27488.1 - 4.2e-10 40.0 0.0 4.2e-10 40.0 0.0 3.9 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 VBB27488.1 - 2.1e-05 24.8 0.0 8.1e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 VBB27488.1 - 2.3e-05 24.2 15.6 5.3e-05 23.0 15.6 1.7 1 0 0 1 1 1 1 PHD-finger DUF5097 PF17020.5 VBB27488.1 - 0.021 15.2 0.2 0.86 10.0 0.2 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5097) WHIM1 PF15612.6 VBB27488.1 - 0.023 14.2 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF3035 PF11233.8 VBB27488.1 - 0.55 10.5 4.7 0.43 10.9 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) SPT16 PF08644.11 VBB27488.1 - 1.2 9.3 13.6 2.2 8.4 3.8 3.7 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) RRT14 PF17075.5 VBB27488.1 - 3.6 7.7 21.4 0.046 13.8 12.4 2.4 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 Methyltransf_16 PF10294.9 VBB27490.1 - 1.2e-18 67.5 0.0 2.6e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase CENP-S PF15630.6 VBB27490.1 - 5.4e-09 36.3 0.2 1.4e-08 35.0 0.2 1.8 1 0 0 1 1 1 1 CENP-S protein Methyltransf_11 PF08241.12 VBB27490.1 - 2.7e-08 34.4 0.0 8.2e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB27490.1 - 5.9e-08 33.3 0.0 2.7e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB27490.1 - 7.5e-07 29.8 0.1 5.2e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB27490.1 - 9.6e-07 28.8 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB27490.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 VBB27490.1 - 5.9e-05 22.6 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB CENP-T_C PF15511.6 VBB27490.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PrmA PF06325.13 VBB27490.1 - 0.0003 20.3 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 VBB27490.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PP1_bind PF15276.6 VBB27490.1 - 0.36 11.2 2.4 1.2 9.5 1.5 2.4 2 1 0 2 2 2 0 Protein phosphatase 1 binding Mito_carr PF00153.27 VBB27491.1 - 4.5e-63 209.2 7.7 4.5e-22 77.8 0.5 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DAGK_cat PF00781.24 VBB27492.1 - 2e-11 43.6 0.0 4.6e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 VBB27492.1 - 0.019 14.3 0.0 0.065 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphofructokinase EloA-BP1 PF15870.5 VBB27493.1 - 6.2e-30 104.6 0.0 6.2e-30 104.6 0.0 3.5 2 1 0 3 3 3 1 ElonginA binding-protein 1 BNIP2 PF12496.8 VBB27493.1 - 0.68 10.4 10.8 0.45 10.9 3.1 3.0 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PGM_PMM_I PF02878.16 VBB27494.1 - 1.2e-32 112.5 0.0 1.9e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 VBB27494.1 - 8.6e-30 103.3 0.0 1.4e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 VBB27494.1 - 1.3e-16 61.0 0.0 2.9e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 VBB27494.1 - 5.5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HMG-CoA_red PF00368.18 VBB27494.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_L37e PF01907.19 VBB27495.1 - 2.3e-28 98.1 12.8 4.1e-28 97.3 12.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 VBB27495.1 - 0.018 15.1 1.5 0.029 14.4 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon SelR PF01641.18 VBB27495.1 - 0.039 14.0 0.4 0.044 13.9 0.4 1.1 1 0 0 1 1 1 0 SelR domain HypA PF01155.19 VBB27495.1 - 0.15 12.0 0.8 0.23 11.5 0.8 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 VBB27495.1 - 0.2 11.1 1.2 0.25 10.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF1462 PF07315.11 VBB27495.1 - 0.22 11.8 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DUF35_N PF12172.8 VBB27495.1 - 0.22 11.4 4.6 0.47 10.4 4.6 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rubredoxin_2 PF18073.1 VBB27495.1 - 0.63 9.8 4.8 3 7.7 0.6 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zn-ribbon_14 PF16503.5 VBB27495.1 - 0.72 9.4 5.2 1.5 8.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon Globin PF00042.22 VBB27497.1 - 1.2e-08 35.5 0.1 1.7e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Globin Kinesin PF00225.23 VBB27498.1 - 4.1e-92 308.7 0.1 4.1e-92 308.7 0.1 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 VBB27498.1 - 1.5e-14 54.2 0.5 1.5e-14 54.2 0.5 2.0 2 0 0 2 2 2 1 Microtubule binding SIN1 PF05422.12 VBB27498.1 - 0.006 17.1 3.1 0.043 14.4 4.1 2.0 2 0 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) Bac_DnaA PF00308.18 VBB27498.1 - 0.013 15.3 0.6 0.081 12.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein YqzE PF14038.6 VBB27498.1 - 0.54 10.3 4.1 1.5 8.9 4.1 1.7 1 0 0 1 1 1 0 YqzE-like protein zf-C2HC5 PF06221.13 VBB27499.1 - 2.6e-12 46.5 10.2 5.2e-12 45.6 10.2 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4827 PF16109.5 VBB27499.1 - 0.56 10.2 2.6 0.5 10.3 0.4 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4827) Mito_carr PF00153.27 VBB27500.1 - 6.6e-13 48.4 0.2 9.6e-05 22.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 VBB27501.1 - 0.00052 19.8 0.0 0.00084 19.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.27 VBB27502.1 - 1.1e-66 220.8 3.7 1.4e-24 85.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein BRAP2 PF07576.12 VBB27503.1 - 1.6e-29 102.0 0.0 4.1e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 VBB27503.1 - 5.1e-20 71.6 1.5 1.6e-19 70.0 1.5 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 VBB27503.1 - 2.2e-09 37.5 6.0 2.2e-09 37.5 6.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB27503.1 - 2.8e-09 36.7 5.9 2.8e-09 36.7 5.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB27503.1 - 5.4e-06 26.2 5.2 5.4e-06 26.2 5.2 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB27503.1 - 1.2e-05 25.5 4.4 1.2e-05 25.5 4.4 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 VBB27503.1 - 2.6e-05 23.8 2.0 2.6e-05 23.8 2.0 2.4 2 0 0 2 2 1 1 RING-like zinc finger SHE3 PF17078.5 VBB27503.1 - 3.5e-05 23.6 15.9 3.5e-05 23.6 15.9 2.3 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 zf-RING_5 PF14634.6 VBB27503.1 - 3.6e-05 23.6 5.2 3.6e-05 23.6 5.2 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB27503.1 - 9.1e-05 22.4 2.5 9.1e-05 22.4 2.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 VBB27503.1 - 0.00017 21.4 4.3 0.00017 21.4 4.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB27503.1 - 0.0061 16.4 5.4 0.0061 16.4 5.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 VBB27503.1 - 0.015 15.3 4.1 0.049 13.7 4.1 2.0 1 0 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 VBB27503.1 - 0.027 14.5 7.3 0.024 14.7 4.2 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atg14 PF10186.9 VBB27503.1 - 0.037 13.1 22.9 0.09 11.8 22.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1890 PF09001.11 VBB27503.1 - 0.044 14.2 0.1 0.36 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) tRNA-synt_His PF13393.6 VBB27503.1 - 0.044 13.0 4.4 0.071 12.4 4.4 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF5505 PF17610.2 VBB27503.1 - 0.069 13.1 0.1 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5505) zf-RING_6 PF14835.6 VBB27503.1 - 0.32 10.9 5.9 0.23 11.3 3.6 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FapA PF03961.13 VBB27503.1 - 0.33 9.5 14.1 0.58 8.7 14.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 VBB27503.1 - 0.45 9.7 11.1 0.88 8.8 11.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 VBB27503.1 - 1.2 8.4 14.5 2.2 7.5 14.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RecR PF02132.15 VBB27503.1 - 1.8 8.2 9.6 1.8 8.2 1.2 3.6 3 0 0 3 3 3 0 RecR protein DUF4407 PF14362.6 VBB27503.1 - 2.1 7.6 14.1 3.4 6.9 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn_ribbon_17 PF17120.5 VBB27503.1 - 3.3 7.4 15.1 0.071 12.7 5.6 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Sod_Fe_N PF00081.22 VBB27503.1 - 7.6 7.1 9.1 14 6.2 1.7 3.3 1 1 2 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain TerY_C PF15616.6 VBB27503.1 - 7.9 6.6 13.7 13 5.9 2.7 2.8 1 1 1 2 2 2 0 TerY-C metal binding domain Pepsin-I3 PF06394.13 VBB27504.1 - 2.4e-68 226.3 2.1 1e-35 121.8 0.1 2.4 2 0 0 2 2 2 2 Pepsin inhibitor-3-like repeated domain DUF3987 PF13148.6 VBB27504.1 - 0.0047 16.0 0.2 0.015 14.3 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) KapB PF08810.10 VBB27504.1 - 0.09 12.9 1.9 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 Kinase associated protein B 4HB_MCP_1 PF12729.7 VBB27504.1 - 0.35 10.4 4.8 3.1 7.3 0.9 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Helicase_C PF00271.31 VBB27505.1 - 2.4e-24 85.8 0.1 5.5e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB27505.1 - 8.8e-23 81.0 0.0 2.1e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Bestrophin PF01062.21 VBB27506.1 - 1.2e-76 257.9 10.7 1.5e-76 257.7 9.7 1.6 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel DB PF01682.19 VBB27506.1 - 4e-15 55.9 9.5 8.7e-15 54.8 9.5 1.6 1 0 0 1 1 1 1 DB module Innexin PF00876.18 VBB27507.1 - 7.6e-98 328.0 8.2 3.4e-89 299.6 6.2 2.0 2 0 0 2 2 2 2 Innexin adh_short PF00106.25 VBB27508.1 - 1.8e-30 105.9 0.0 1.2e-29 103.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Glycos_transf_2 PF00535.26 VBB27508.1 - 1.7e-29 102.8 0.0 4.5e-29 101.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 adh_short_C2 PF13561.6 VBB27508.1 - 2.1e-16 60.2 0.0 1.6e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB27508.1 - 8.3e-05 22.6 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_transf_7C PF02709.14 VBB27508.1 - 0.00029 20.4 0.1 0.00063 19.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 VBB27508.1 - 0.0017 17.9 0.1 0.017 14.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 VBB27508.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Epimerase PF01370.21 VBB27508.1 - 0.021 14.3 0.0 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CblD PF07434.11 VBB27508.1 - 0.063 12.2 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator MYEOV2 PF15004.6 VBB27508.1 - 0.14 12.6 0.5 0.41 11.1 0.1 1.9 2 0 0 2 2 2 0 Myeloma-overexpressed-like SIR2 PF02146.17 VBB27510.1 - 1.7e-25 90.0 0.0 4.3e-17 62.6 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 VBB27510.1 - 0.003 17.3 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AAA_17 PF13207.6 VBB27510.1 - 0.15 12.5 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain HTH_33 PF13592.6 VBB27511.1 - 0.051 13.2 0.0 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix 2OG-FeII_Oxy_2 PF13532.6 VBB27512.1 - 0.00021 21.5 0.2 0.0004 20.6 0.2 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cullin PF00888.22 VBB27513.1 - 3.1e-20 72.4 0.3 3.1e-20 72.4 0.3 2.2 3 0 0 3 3 3 1 Cullin family ANAPC2 PF08672.11 VBB27513.1 - 2.9e-10 40.5 0.0 8.8e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 CCM2_C PF16545.5 VBB27513.1 - 0.022 15.3 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Pyrophosphatase PF00719.19 VBB27514.1 - 7.3e-55 185.2 0.2 1.9e-54 183.8 0.2 1.8 1 0 0 1 1 1 1 Inorganic pyrophosphatase Nse4_C PF08743.10 VBB27514.1 - 1.2e-23 83.2 0.9 8.1e-23 80.5 0.1 2.8 3 0 0 3 3 3 1 Nse4 C-terminal BORCS6 PF10157.9 VBB27514.1 - 0.037 14.3 0.5 0.31 11.3 0.0 2.6 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 6 Xpo1 PF08389.12 VBB27514.1 - 0.12 12.4 1.6 0.34 11.0 1.6 1.8 1 0 0 1 1 1 0 Exportin 1-like protein DCB PF16213.5 VBB27514.1 - 0.27 10.9 3.3 0.24 11.0 0.8 2.0 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 POX PF07526.11 VBB27514.1 - 0.9 10.1 3.2 0.63 10.6 0.5 2.0 2 0 0 2 2 2 0 Associated with HOX bVLRF1 PF18826.1 VBB27515.1 - 3.8e-47 159.9 0.0 1.1e-46 158.4 0.0 1.8 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 VBB27515.1 - 2.6e-10 40.0 6.8 9.3e-10 38.2 4.0 2.7 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 VBB27515.1 - 1.5e-05 25.2 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB27515.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB27515.1 - 0.015 15.8 0.0 0.055 14.0 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 VBB27515.1 - 0.023 15.1 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat DUF2407 PF10302.9 VBB27515.1 - 3.9 8.1 0.0 3.9 8.1 0.0 3.5 3 1 0 3 3 3 0 DUF2407 ubiquitin-like domain SPC22 PF04573.12 VBB27516.1 - 3.9e-47 159.9 2.7 5.6e-47 159.4 2.7 1.2 1 0 0 1 1 1 1 Signal peptidase subunit NUDIX PF00293.28 VBB27516.1 - 1.2e-13 51.2 0.0 2.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain UCH PF00443.29 VBB27517.1 - 5.9e-60 202.9 3.1 8e-60 202.5 3.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB27517.1 - 4.8e-27 95.4 8.8 9.7e-27 94.4 8.8 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 VBB27517.1 - 0.00075 19.1 11.3 0.031 13.7 11.3 3.0 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase SPARC_Ca_bdg PF10591.9 VBB27519.1 - 6.6e-14 52.2 3.5 1.2e-13 51.4 3.5 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 VBB27519.1 - 1.8e-13 50.0 5.6 1.1e-12 47.4 4.0 2.3 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat EF-hand_1 PF00036.32 VBB27519.1 - 0.00018 20.8 0.0 0.01 15.3 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 VBB27519.1 - 0.0017 17.8 0.0 0.0058 16.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 VBB27519.1 - 0.0069 16.2 0.0 0.063 13.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 VBB27519.1 - 0.036 14.5 0.1 0.097 13.1 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain pair BBS2_C PF14782.6 VBB27520.1 - 2.3e-126 422.1 12.6 2.9e-126 421.7 12.6 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 VBB27520.1 - 1e-35 122.0 1.6 3e-33 114.1 0.0 3.6 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 VBB27520.1 - 3e-11 43.2 5.9 6.3e-11 42.1 2.2 3.3 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal PQQ_2 PF13360.6 VBB27520.1 - 0.00027 20.6 0.0 0.00059 19.5 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Itfg2 PF15907.5 VBB27520.1 - 0.0096 15.0 1.1 2.3 7.1 0.1 3.4 1 1 2 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 E7 PF00527.18 VBB27520.1 - 0.11 12.7 0.5 0.41 10.9 0.5 2.0 1 0 0 1 1 1 0 E7 protein, Early protein Pkinase PF00069.25 VBB27521.1 - 2.4e-61 207.4 0.1 2.9e-61 207.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27521.1 - 3.3e-37 128.2 0.0 4.2e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB27521.1 - 3e-07 30.1 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB27521.1 - 0.0035 16.4 1.2 0.01 14.8 1.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB27521.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3599 PF12206.8 VBB27521.1 - 0.059 13.7 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) FTA2 PF13095.6 VBB27521.1 - 0.082 12.5 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CorA PF01544.18 VBB27522.1 - 0.11 11.8 8.8 0.22 10.8 8.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.8 VBB27522.1 - 1.5 8.1 11.5 2 7.6 10.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 VBB27522.1 - 2.8 8.3 10.5 2.9 8.2 0.3 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FancD2 PF14631.6 VBB27523.1 - 9.3e-44 149.3 38.8 1.5e-42 145.3 38.8 2.3 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease F_actin_bind PF08919.10 VBB27523.1 - 0.1 12.7 1.2 0.47 10.6 0.1 2.7 2 0 0 2 2 2 0 F-actin binding FN3_7 PF18447.1 VBB27523.1 - 0.47 10.8 3.8 0.34 11.3 0.3 2.8 2 0 0 2 2 2 0 Fibronectin type III domain Planc_extracel PF07595.12 VBB27523.1 - 5 7.1 6.1 28 4.8 2.4 2.9 2 0 0 2 2 2 0 Planctomycete extracellular Per1 PF04080.13 VBB27524.1 - 2.3e-44 152.1 18.5 9.7e-36 123.8 10.4 2.1 1 1 1 2 2 2 2 Per1-like family JAMP PF05571.12 VBB27525.1 - 1.1e-90 304.3 22.3 1.2e-90 304.1 22.3 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein FtsK_4TM PF13491.6 VBB27525.1 - 0.51 10.0 6.2 0.067 12.9 1.6 2.0 2 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Seipin PF06775.14 VBB27526.1 - 1.7e-24 87.1 0.9 2.3e-24 86.6 0.9 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Pkinase PF00069.25 VBB27527.1 - 4.6e-16 59.0 0.1 5.4e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27527.1 - 1.5e-08 34.2 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB27527.1 - 9.5e-06 24.6 0.0 2.3e-05 23.4 0.0 1.5 1 1 1 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 VBB27527.1 - 0.00079 19.1 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pro_3_hydrox_C PF05373.11 VBB27527.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Peptidase_S10 PF00450.22 VBB27528.1 - 2.7e-127 425.7 3.3 3.2e-127 425.4 3.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 VBB27528.1 - 0.013 15.0 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family ATP-synt_C PF00137.21 VBB27530.1 - 1.5e-19 70.1 30.9 3e-12 46.7 9.5 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Sec63 PF02889.16 VBB27531.1 - 1.4e-50 171.8 0.4 2.7e-50 170.9 0.4 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_PWI PF18149.1 VBB27531.1 - 9e-38 128.9 2.0 9e-38 128.9 2.0 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain DEAD PF00270.29 VBB27531.1 - 1.7e-25 89.8 0.1 6.5e-25 87.9 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB27531.1 - 2.8e-15 56.7 0.0 9.8e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 VBB27531.1 - 3.1e-07 30.7 0.0 5.1e-06 26.8 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 VBB27531.1 - 0.00076 19.8 0.4 0.0065 16.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.23 VBB27531.1 - 0.018 13.8 0.1 0.045 12.5 0.1 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain RuvB_N PF05496.12 VBB27531.1 - 0.039 13.7 0.2 8.8 6.0 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 VBB27531.1 - 0.29 10.9 2.7 0.61 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain Sec63 PF02889.16 VBB27532.1 - 4.2e-96 321.1 3.2 4.7e-69 232.4 1.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 VBB27532.1 - 2e-20 73.3 0.0 7e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB27532.1 - 5.8e-08 32.9 0.0 9.9e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF603 PF04645.12 VBB27532.1 - 0.0011 18.7 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF603 HLH PF00010.26 VBB27533.1 - 3.8e-17 62.0 5.6 3.8e-17 62.0 5.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Lipase_chap PF03280.14 VBB27533.1 - 0.026 14.5 5.2 0.022 14.7 4.4 1.3 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein Use1 PF09753.9 VBB27533.1 - 2.8 7.6 10.9 5.8 6.6 10.9 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Thioredoxin_7 PF13899.6 VBB27534.1 - 4.2e-14 52.5 0.1 7.1e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 VBB27534.1 - 2e-08 34.3 0.2 2e-08 34.3 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF255 AhpC-TSA PF00578.21 VBB27534.1 - 0.00086 19.2 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 VBB27534.1 - 0.0014 19.1 0.3 0.0027 18.1 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 VBB27534.1 - 0.0034 17.7 0.9 0.045 14.1 0.8 2.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 VBB27534.1 - 0.057 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin APG9 PF04109.16 VBB27534.1 - 0.087 11.8 0.3 0.11 11.5 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 IBN_N PF03810.19 VBB27537.1 - 3.9e-14 52.3 0.0 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Rsbr_N PF08678.10 VBB27537.1 - 0.0057 16.7 0.1 0.083 13.0 0.0 2.7 2 0 0 2 2 2 1 Rsbr N terminal Cse1 PF08506.10 VBB27537.1 - 0.0071 15.2 0.4 0.023 13.6 0.4 1.9 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 VBB27537.1 - 0.029 14.4 0.5 3.1 7.8 0.2 3.9 2 0 0 2 2 2 0 Exportin 1-like protein DUF2457 PF10446.9 VBB27537.1 - 0.32 10.1 7.0 0.48 9.5 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BNIP2 PF12496.8 VBB27537.1 - 3.3 8.1 6.1 7.7 7.0 6.1 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PPP4R2 PF09184.11 VBB27538.1 - 4.2e-28 98.8 0.5 9.6e-28 97.6 0.5 1.7 1 1 0 1 1 1 1 PPP4R2 SF3A2 PF16835.5 VBB27539.1 - 1.4e-39 134.3 0.3 3.4e-39 133.1 0.3 1.7 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) RNase_PH PF01138.21 VBB27539.1 - 1.3e-36 126.0 0.0 2.3e-17 63.7 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 VBB27539.1 - 1.3e-09 38.0 0.3 7.5e-09 35.5 0.1 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 zf-met PF12874.7 VBB27539.1 - 1.1e-06 28.8 2.0 2.9e-06 27.5 2.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PNPase PF03726.14 VBB27539.1 - 8.7e-05 22.9 0.1 0.0002 21.8 0.1 1.7 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain CactinC_cactus PF09732.9 VBB27539.1 - 0.00016 21.6 0.8 0.00038 20.4 0.8 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein KH_1 PF00013.29 VBB27539.1 - 0.0053 16.6 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 KH domain Syndecan PF01034.20 VBB27539.1 - 0.23 11.4 0.9 0.66 9.9 0.9 1.7 1 0 0 1 1 1 0 Syndecan domain TPR_1 PF00515.28 VBB27540.1 - 3.1e-37 124.9 7.5 4.5e-07 29.4 0.3 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27540.1 - 1.5e-36 121.6 1.4 0.00023 21.0 0.2 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 VBB27540.1 - 6.4e-24 83.4 13.2 2.2e-07 30.5 0.2 8.1 3 3 5 8 8 8 7 TPR repeat TPR_16 PF13432.6 VBB27540.1 - 4.5e-22 78.4 0.2 5.5e-05 23.7 0.0 5.4 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27540.1 - 2.5e-21 74.1 7.3 0.0048 17.0 0.0 8.6 9 1 1 10 10 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 VBB27540.1 - 2.9e-20 72.2 0.5 1.1e-05 25.5 0.0 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 VBB27540.1 - 6.2e-20 70.2 1.3 0.028 15.2 0.0 8.1 3 3 5 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.31 VBB27540.1 - 7.6e-20 70.8 2.2 7.6e-20 70.8 2.2 3.0 3 1 0 3 3 3 1 DnaJ domain TPR_12 PF13424.6 VBB27540.1 - 1.1e-18 67.3 4.4 0.0011 19.2 0.0 5.7 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 VBB27540.1 - 6.1e-18 65.1 5.4 0.00054 20.4 0.1 5.7 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 VBB27540.1 - 9.4e-18 63.2 10.8 0.0036 17.6 0.2 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 VBB27540.1 - 1.7e-10 40.8 0.4 0.3 11.8 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB27540.1 - 1.1e-08 34.7 3.0 1.1 9.2 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB27540.1 - 3.6e-08 32.9 3.2 1.5 9.0 0.2 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 VBB27540.1 - 2.6e-07 30.1 0.3 0.79 8.9 0.0 5.2 2 1 3 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27540.1 - 4.2e-07 30.1 7.6 0.26 11.5 0.1 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 VBB27540.1 - 1.7e-06 28.3 2.9 0.24 11.8 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 VBB27540.1 - 3.4e-06 27.6 2.5 1.7 9.1 0.0 4.8 2 2 2 4 4 4 1 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 VBB27540.1 - 3.4e-06 26.4 0.4 0.011 15.2 0.1 4.2 4 0 0 4 4 4 1 SHNi-TPR TPR_21 PF09976.9 VBB27540.1 - 9.4e-06 25.5 7.2 5.8e-05 22.9 0.1 3.1 2 2 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 VBB27540.1 - 0.085 13.5 0.0 40 5.2 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 VBB27540.1 - 0.088 12.9 6.3 9 6.5 1.0 4.6 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 VBB27540.1 - 0.11 12.6 0.9 13 5.9 0.0 3.5 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) FlbT PF07378.11 VBB27540.1 - 0.17 12.0 1.1 6.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Flagellar protein FlbT HTH_Bact PF18768.1 VBB27540.1 - 0.57 9.8 2.9 13 5.5 0.1 3.4 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain FGGY_N PF00370.21 VBB27541.1 - 2.8e-33 115.5 0.0 1.7e-31 109.7 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 VBB27541.1 - 6.7e-23 81.5 0.1 1e-22 80.9 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Carboxyl_trans PF01039.22 VBB27542.1 - 6.1e-143 477.0 0.0 8.4e-143 476.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 VBB27542.1 - 1.5e-70 238.4 10.1 1.2e-43 149.5 1.7 2.1 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 VBB27542.1 - 1.1e-49 168.9 0.2 2.3e-49 167.8 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 VBB27542.1 - 1.9e-21 76.6 0.0 4.9e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 VBB27542.1 - 8.5e-19 67.6 0.0 2.7e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_3 PF02655.14 VBB27542.1 - 0.002 18.2 0.0 0.0059 16.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 VBB27542.1 - 0.0034 16.9 0.1 0.02 14.4 0.0 2.3 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 VBB27542.1 - 0.1 12.5 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 Biotin-requiring enzyme zf-C3HC4_2 PF13923.6 VBB27543.1 - 1.6e-08 34.2 9.4 1.6e-08 34.2 9.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 VBB27543.1 - 1.3e-06 29.0 0.0 3.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 VBB27543.1 - 2.6e-06 27.2 10.6 7.6e-06 25.7 10.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB27543.1 - 2e-05 24.3 10.4 4.9e-05 23.1 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB27543.1 - 3.4e-05 23.8 5.4 0.00012 22.1 5.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 VBB27543.1 - 6.8e-05 23.1 10.5 6.8e-05 23.1 10.5 2.2 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 VBB27543.1 - 0.00051 19.9 11.8 0.0015 18.4 11.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 VBB27543.1 - 0.012 15.4 9.0 0.045 13.6 9.2 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 VBB27543.1 - 0.022 14.6 3.0 0.054 13.4 3.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 VBB27543.1 - 0.055 13.3 5.1 0.18 11.7 5.1 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 VBB27543.1 - 0.14 12.5 9.1 0.46 10.8 9.1 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 VBB27543.1 - 0.22 11.7 6.8 0.55 10.4 6.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 VBB27543.1 - 0.24 11.2 7.1 0.54 10.1 7.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 VBB27543.1 - 0.39 10.5 5.1 0.81 9.5 5.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 VBB27543.1 - 1.5 8.9 7.7 14 5.9 7.7 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Histone PF00125.24 VBB27544.1 - 1.8e-49 167.5 4.3 1.1e-48 164.9 4.3 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 VBB27544.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 VBB27544.1 - 0.00034 20.9 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 VBB27544.1 - 0.027 15.1 3.2 0.035 14.7 3.2 1.3 1 1 0 1 1 1 0 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 VBB27544.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tmpp129 PF10272.9 VBB27545.1 - 2.6e-110 369.1 5.4 3e-110 368.9 5.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor IBR PF01485.21 VBB27545.1 - 6.4 7.1 11.7 42 4.5 11.7 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Nramp PF01566.18 VBB27546.1 - 2.6e-95 319.4 5.3 2.6e-95 319.4 5.3 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein UPF0182 PF03699.13 VBB27546.1 - 0.43 8.6 5.2 0.13 10.3 2.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Tetraspanin PF00335.20 VBB27547.1 - 9.5e-26 90.9 5.7 1.1e-25 90.7 5.7 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 VBB27547.1 - 0.042 14.0 6.0 0.033 14.3 1.2 2.2 2 0 0 2 2 2 0 CD20-like family Seipin PF06775.14 VBB27547.1 - 0.87 9.7 4.5 0.22 11.6 1.1 1.7 2 0 0 2 2 2 0 Putative adipose-regulatory protein (Seipin) TMEMspv1-c74-12 PF11044.8 VBB27547.1 - 1.5 8.8 4.5 19 5.3 0.1 2.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Kunitz_BPTI PF00014.23 VBB27548.1 - 7.9e-161 522.3 104.9 1.8e-17 63.3 4.1 10.6 10 0 0 10 10 10 10 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 VBB27548.1 - 6.6e-46 154.4 148.3 2.5e-09 37.4 6.5 10.9 10 0 0 10 10 10 7 Lustrin, cysteine-rich repeated domain DUF4955 PF16315.5 VBB27548.1 - 0.05 13.8 0.1 1.1 9.5 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4955) GYF_2 PF14237.6 VBB27548.1 - 1 9.2 8.3 43 4.0 0.0 5.0 5 0 0 5 5 5 0 GYF domain 2 Sirohm_synth_C PF14823.6 VBB27549.1 - 0.014 15.0 0.6 0.085 12.5 0.0 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Kunitz_BPTI PF00014.23 VBB27550.1 - 5.1e-14 52.2 3.5 8e-14 51.6 3.5 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Yip1 PF04893.17 VBB27551.1 - 2.7e-11 43.5 23.2 4.9e-11 42.6 23.1 1.6 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 VBB27551.1 - 1.3 8.7 10.8 2 8.2 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) EMP24_GP25L PF01105.24 VBB27552.1 - 1.2e-28 100.3 0.2 1.2e-28 100.3 0.2 4.2 3 1 1 4 4 4 1 emp24/gp25L/p24 family/GOLD zf-B_box PF00643.24 VBB27552.1 - 6.2e-07 29.5 8.7 6.2e-07 29.5 8.7 4.7 4 0 0 4 4 4 1 B-box zinc finger AIP3 PF03915.13 VBB27552.1 - 4.2e-06 26.1 14.8 4.2e-06 26.1 14.8 2.5 3 0 0 3 3 3 1 Actin interacting protein 3 zf-RING_UBOX PF13445.6 VBB27552.1 - 0.00016 21.6 3.0 0.00016 21.6 3.0 3.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 VBB27552.1 - 0.00017 21.5 2.7 0.00017 21.5 2.7 4.6 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB27552.1 - 0.00037 20.3 3.4 0.00037 20.3 3.4 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB27552.1 - 0.0022 17.8 4.6 0.0022 17.8 4.6 4.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB27552.1 - 0.0037 17.6 4.3 0.0037 17.6 4.3 4.6 4 0 0 4 4 4 1 Ring finger domain DICT PF10069.9 VBB27552.1 - 0.11 12.2 0.8 0.28 11.0 0.2 2.0 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system HlyD_2 PF12700.7 VBB27552.1 - 1.9 7.2 8.2 0.31 9.7 3.3 2.0 2 0 0 2 2 2 0 HlyD family secretion protein ATP-synt_E PF05680.12 VBB27552.1 - 2 8.8 4.6 6.9 7.1 4.6 1.9 1 0 0 1 1 1 0 ATP synthase E chain RRM_1 PF00076.22 VBB27553.1 - 3.3e-39 132.5 0.1 4.3e-14 52.1 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 VBB27553.1 - 7e-25 86.8 0.8 1.9e-24 85.4 0.2 2.1 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_5 PF13893.6 VBB27553.1 - 3.3e-06 26.7 0.0 1.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB27553.1 - 0.00056 20.0 0.0 15 5.8 0.0 4.3 3 1 1 4 4 4 2 RNA recognition motif RRM_2 PF04059.12 VBB27553.1 - 0.0025 18.0 0.0 2 8.7 0.0 3.1 2 1 1 3 3 3 1 RNA recognition motif 2 RRM_occluded PF16842.5 VBB27553.1 - 0.0029 17.4 0.0 0.067 13.1 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif LAP1C PF05609.12 VBB27553.1 - 0.47 9.5 14.8 0.74 8.8 14.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ATP-synt_ab PF00006.25 VBB27554.1 - 2.4e-74 249.6 0.0 3.8e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 VBB27554.1 - 7.6e-47 158.8 2.9 1.2e-46 158.1 2.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 VBB27554.1 - 3.1e-17 62.9 1.6 7.6e-17 61.6 1.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 VBB27554.1 - 0.014 15.6 1.4 0.024 14.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Ras PF00071.22 VBB27555.1 - 9.1e-67 223.7 0.4 1.2e-66 223.3 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB27555.1 - 3.1e-34 117.8 0.1 5.8e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB27555.1 - 2.2e-15 56.5 0.1 3e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB27555.1 - 5.7e-05 22.6 0.8 0.00012 21.5 0.8 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 VBB27555.1 - 0.0001 21.8 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 VBB27555.1 - 0.00099 18.7 0.2 0.0018 17.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB27555.1 - 0.0015 18.4 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 VBB27555.1 - 0.0039 17.3 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3963 PF13124.6 VBB27555.1 - 0.03 14.3 0.8 0.058 13.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_7 PF12775.7 VBB27555.1 - 0.035 13.6 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 VBB27555.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Mdv1 PF11542.8 VBB27555.1 - 0.18 11.8 0.5 0.98 9.4 0.5 2.1 1 1 0 1 1 1 0 Mitochondrial division protein 1 Tropomodulin PF03250.14 VBB27556.1 - 3.1e-51 173.1 2.1 3.1e-51 173.1 2.1 1.8 3 0 0 3 3 3 1 Tropomodulin LRR_4 PF12799.7 VBB27556.1 - 0.069 13.6 0.3 0.29 11.6 0.1 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) PDZ_5 PF17817.1 VBB27558.1 - 4e-21 75.1 0.2 4e-21 75.1 0.2 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 VBB27558.1 - 3.1e-12 46.7 1.0 6.5e-12 45.6 1.0 1.6 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 VBB27558.1 - 1.1e-05 25.5 0.2 4.3e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 VBB27558.1 - 5.7e-05 23.5 0.9 0.00012 22.4 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 VBB27558.1 - 0.0043 16.9 2.0 0.031 14.1 0.2 2.9 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 VBB27558.1 - 0.013 15.8 0.1 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 PDZ domain HSBP1 PF06825.12 VBB27558.1 - 0.016 15.0 2.8 2.5 8.0 0.1 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF2333 PF10095.9 VBB27558.1 - 0.17 10.9 2.0 0.35 9.8 2.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) DUF745 PF05335.13 VBB27558.1 - 0.51 10.0 10.5 1.4 8.6 10.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SpoIISA_toxin PF14171.6 VBB27558.1 - 0.56 9.9 2.5 1.1 8.9 2.5 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Pox_A_type_inc PF04508.12 VBB27558.1 - 3 7.9 21.2 0.031 14.1 1.9 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Exonuc_VII_L PF02601.15 VBB27558.1 - 3.2 7.2 13.5 0.19 11.2 8.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 VBB27558.1 - 7.3 4.4 7.8 14 3.5 7.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PDEase_I PF00233.19 VBB27559.1 - 5.5e-68 229.2 6.6 2.1e-67 227.3 3.8 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 VBB27559.1 - 1.7e-16 61.1 0.0 3.1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 VBB27559.1 - 8.7e-09 35.8 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 VBB27559.1 - 1e-08 35.6 0.0 3.5e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 VBB27559.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor CLASP_N PF12348.8 VBB27560.1 - 7.3e-05 22.4 0.3 0.00013 21.6 0.3 1.4 1 0 0 1 1 1 1 CLASP N terminal HycH PF07450.11 VBB27560.1 - 0.068 13.5 0.3 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH SRPRB PF09439.10 VBB27562.1 - 3.9e-47 160.0 0.0 5.4e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 VBB27562.1 - 8.9e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB27562.1 - 2e-09 37.5 0.0 3.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 VBB27562.1 - 3.7e-06 26.5 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 VBB27562.1 - 3.3e-05 24.1 0.0 6.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 VBB27562.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 VBB27562.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Ras family AAA_14 PF13173.6 VBB27562.1 - 0.028 14.4 0.0 0.077 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 VBB27562.1 - 0.031 13.8 0.0 1.4 8.4 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 VBB27562.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 VBB27562.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 VBB27562.1 - 0.16 11.3 0.0 0.44 9.9 0.0 1.6 2 0 0 2 2 2 0 KaiC Ribosomal_L14 PF00238.19 VBB27563.1 - 1.2e-07 31.8 0.0 3.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e DUF5522 PF17653.1 VBB27563.1 - 7.1e-06 25.9 0.1 2.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5522) BORCS6 PF10157.9 VBB27564.1 - 1e-35 123.2 3.8 1.3e-35 122.9 3.8 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Baculo_PEP_C PF04513.12 VBB27564.1 - 0.0084 16.2 1.3 0.62 10.1 0.1 2.7 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus CutA1 PF03091.15 VBB27564.1 - 0.017 15.0 0.4 0.032 14.1 0.4 1.4 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Rad33 PF08730.10 VBB27564.1 - 0.022 14.7 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Rad33 Laminin_II PF06009.12 VBB27564.1 - 0.023 14.7 0.4 0.047 13.7 0.2 1.6 1 1 0 1 1 1 0 Laminin Domain II AAA_13 PF13166.6 VBB27564.1 - 0.027 13.1 0.1 0.031 12.9 0.1 1.0 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 VBB27564.1 - 0.028 14.7 1.0 0.24 11.7 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ST7 PF04184.12 VBB27564.1 - 0.032 12.7 0.2 0.04 12.4 0.2 1.0 1 0 0 1 1 1 0 ST7 protein NPV_P10 PF05531.12 VBB27564.1 - 0.27 11.7 2.3 32 5.1 2.3 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PHR PF08005.12 VBB27565.1 - 8.9e-70 234.2 0.0 5e-36 124.6 0.0 2.8 2 0 0 2 2 2 2 PHR domain RCC1 PF00415.18 VBB27565.1 - 4.2e-19 68.9 13.8 2.7e-10 40.7 1.4 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB27565.1 - 1.4e-14 53.4 20.2 9.3e-06 25.3 1.1 5.8 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat SH3_3 PF08239.11 VBB27565.1 - 2.2e-07 31.0 0.8 5.2e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain zf-RING_2 PF13639.6 VBB27565.1 - 1.6e-05 25.1 6.9 1.6e-05 25.1 6.9 5.7 5 0 0 5 5 5 1 Ring finger domain zf-B_box PF00643.24 VBB27565.1 - 0.00063 19.8 8.1 0.00063 19.8 8.1 4.5 4 0 0 4 4 4 1 B-box zinc finger zf-rbx1 PF12678.7 VBB27565.1 - 0.0024 18.1 9.7 0.024 14.9 9.7 2.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3619 PF12279.8 VBB27565.1 - 0.0077 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) DUF2766 PF10964.8 VBB27565.1 - 0.088 12.8 0.3 0.36 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) IFT81_CH PF18383.1 VBB27566.1 - 6.2e-24 84.6 0.2 6.7e-24 84.5 0.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain DUF1987 PF09345.10 VBB27566.1 - 0.047 13.4 0.1 0.052 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) O-FucT PF10250.9 VBB27567.1 - 7.2e-58 196.9 3.3 9.7e-47 160.3 0.5 2.1 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 VBB27567.1 - 0.019 14.2 0.2 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 11 Muted PF14942.6 VBB27567.1 - 0.078 13.3 0.6 0.14 12.5 0.6 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sec1 PF00995.23 VBB27568.1 - 4.8e-121 405.8 0.2 5.4e-121 405.6 0.2 1.0 1 0 0 1 1 1 1 Sec1 family WASH-7_C PF14746.6 VBB27568.1 - 0.055 13.2 0.8 0.12 12.0 0.8 1.6 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Strep_SA_rep PF06696.11 VBB27568.1 - 6.7 6.8 6.6 8 6.6 0.1 3.5 3 1 1 4 4 4 0 Streptococcal surface antigen repeat WD40 PF00400.32 VBB27569.1 - 1.7e-06 28.6 11.1 14 6.7 0.0 7.9 9 0 0 9 9 9 4 WD domain, G-beta repeat WD40_like PF17005.5 VBB27569.1 - 0.0013 18.2 9.7 0.0024 17.3 0.1 4.0 3 1 2 5 5 5 1 WD40-like domain Peptidase_S64 PF08192.11 VBB27569.1 - 2.2 6.7 10.4 3.4 6.1 10.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 TMF_DNA_bd PF12329.8 VBB27569.1 - 9.1 6.4 27.9 0.15 12.1 18.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Guanylate_cyc PF00211.20 VBB27570.1 - 7.4e-54 182.1 0.2 1.1e-53 181.6 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 VBB27570.1 - 2.4e-20 73.1 0.1 5e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 VBB27570.1 - 1.8e-18 66.8 2.4 1.8e-15 57.0 2.3 2.2 1 1 1 2 2 2 2 Heme NO binding associated MerR_2 PF13591.6 VBB27570.1 - 0.015 15.1 0.7 0.53 10.2 0.0 2.7 2 1 0 2 2 2 0 MerR HTH family regulatory protein DUF2175 PF09943.9 VBB27570.1 - 0.05 13.9 0.5 0.15 12.4 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Rnk_N PF14760.6 VBB27570.1 - 0.34 11.4 2.2 0.77 10.3 2.2 1.6 1 0 0 1 1 1 0 Rnk N-terminus Tup_N PF08581.10 VBB27571.1 - 0.032 14.5 1.8 0.032 14.5 1.8 2.8 3 0 0 3 3 3 0 Tup N-terminal DUF948 PF06103.11 VBB27571.1 - 0.84 9.9 5.8 29 5.0 0.2 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 VBB27571.1 - 1.5 9.3 7.0 3.3 8.2 0.2 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 VBB27571.1 - 8.6 6.5 21.9 0.15 12.1 1.2 3.9 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase RRM_1 PF00076.22 VBB27572.1 - 1.3e-87 287.7 5.0 5.6e-21 74.1 0.4 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 VBB27572.1 - 3.3e-29 100.8 3.7 3.2e-27 94.5 1.8 3.2 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 VBB27572.1 - 1.6e-10 40.6 1.6 0.027 14.1 0.0 4.7 2 1 2 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 VBB27572.1 - 5e-10 39.2 1.1 0.21 11.6 0.0 4.5 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 VBB27572.1 - 2.8e-07 30.6 0.6 0.065 13.4 0.1 4.9 3 1 1 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 VBB27572.1 - 1.6e-06 27.9 0.0 0.15 11.9 0.0 3.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif SET_assoc PF11767.8 VBB27572.1 - 6.1e-06 25.8 0.5 2.3 7.9 0.1 4.4 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 VBB27572.1 - 3.4e-05 23.8 7.0 0.21 11.6 0.1 3.8 4 0 0 4 4 4 2 RNA binding motif Limkain-b1 PF11608.8 VBB27572.1 - 0.0001 22.3 0.5 1.8 8.7 0.0 4.2 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.11 VBB27572.1 - 0.0077 15.9 3.1 11 5.7 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease B OB domain PHM7_cyt PF14703.6 VBB27572.1 - 0.0081 16.4 1.8 6 7.1 0.0 4.3 4 1 1 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter DHHA1 PF02272.19 VBB27572.1 - 0.37 11.2 2.3 24 5.3 0.2 3.2 2 1 1 3 3 3 0 DHHA1 domain Cpn60_TCP1 PF00118.24 VBB27574.1 - 3.1e-155 517.6 12.7 3.6e-155 517.3 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2624 PF11116.8 VBB27574.1 - 0.45 11.4 4.3 1.2 10.1 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2624) DUF446 PF04287.12 VBB27575.1 - 0.11 12.6 0.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 tRNA pseudouridine synthase C Metallophos PF00149.28 VBB27576.1 - 7.6e-37 127.8 0.0 9.5e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB27576.1 - 4.9e-11 42.9 0.0 9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain UBA_3 PF09288.10 VBB27576.1 - 0.19 11.5 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UQ_con PF00179.26 VBB27577.1 - 7.4e-09 35.4 0.0 8e-08 32.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB27577.1 - 0.0045 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 VBB27577.1 - 0.0061 16.8 0.1 0.95 9.8 0.1 2.4 2 0 0 2 2 2 2 RWD domain Josephin PF02099.17 VBB27577.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.5 1 1 0 1 1 1 0 Josephin C2 PF00168.30 VBB27578.1 - 7.4e-09 35.8 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain PCI PF01399.27 VBB27579.1 - 8.1e-22 77.7 0.6 2.7e-21 76.1 0.6 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 VBB27579.1 - 0.0034 17.3 0.8 9.4 6.5 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB27579.1 - 0.037 14.9 0.3 26 6.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN6_N PF18055.1 VBB27579.1 - 0.05 14.0 11.9 1.8 8.9 0.0 3.5 1 1 2 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_12 PF13424.6 VBB27579.1 - 0.45 10.8 3.9 2.5 8.4 0.5 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27579.1 - 0.53 10.5 9.3 1.7 9.0 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat COR PF16095.5 VBB27581.1 - 0.14 11.9 2.2 0.36 10.6 0.1 2.3 2 1 0 2 2 2 0 C-terminal of Roc, COR, domain wnt PF00110.19 VBB27582.1 - 4.1e-31 108.7 0.3 5.1e-31 108.4 0.3 1.0 1 0 0 1 1 1 1 wnt family wnt PF00110.19 VBB27583.1 - 9.5e-65 219.2 29.0 9.5e-65 219.2 29.0 2.5 2 1 0 2 2 2 1 wnt family Med3 PF11593.8 VBB27583.1 - 0.016 14.4 8.2 0.023 13.9 8.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf_ZIC PF18366.1 VBB27583.1 - 0.042 14.0 4.3 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain FSA_C PF10479.9 VBB27583.1 - 1.9 6.5 11.9 2.8 6.0 11.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 VBB27583.1 - 2.5 8.1 30.4 5.9 6.9 30.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Talin_middle PF09141.10 VBB27584.1 - 5e-48 163.2 0.4 5e-48 163.2 0.4 15.0 10 4 2 13 13 13 1 Talin, middle domain I_LWEQ PF01608.17 VBB27584.1 - 1.9e-47 161.3 168.8 2.2e-44 151.4 12.3 17.3 7 4 9 17 17 17 6 I/LWEQ domain FERM_f0 PF16511.5 VBB27584.1 - 2.6e-27 94.9 0.2 5.6e-26 90.7 0.1 3.2 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 VBB27584.1 - 8.5e-27 93.9 3.0 1.9e-26 92.8 0.1 3.4 2 1 0 2 2 2 1 FERM central domain VBS PF08913.10 VBB27584.1 - 4e-20 72.5 0.1 4e-20 72.5 0.1 10.8 10 2 2 12 12 11 2 Vinculin Binding Site FERM_N PF09379.10 VBB27584.1 - 1.2e-17 63.5 0.2 1.6e-14 53.5 0.1 3.1 2 0 0 2 2 2 2 FERM N-terminal domain IRS PF02174.17 VBB27584.1 - 2.3e-05 24.2 0.0 0.00011 22.0 0.0 2.2 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ACBP PF00887.19 VBB27584.1 - 0.0021 18.2 0.8 0.0061 16.7 0.0 2.3 2 0 0 2 2 2 1 Acyl CoA binding protein Med28 PF11594.8 VBB27584.1 - 0.019 15.0 0.9 1.5 8.9 0.1 3.6 2 0 0 2 2 2 0 Mediator complex subunit 28 SipA_VBS PF17985.1 VBB27584.1 - 0.12 12.3 0.0 0.12 12.3 0.0 6.7 7 0 0 7 7 6 0 SipA vinculin binding site Phage_T7_Capsid PF05396.11 VBB27584.1 - 2.1 8.8 5.9 73 3.7 0.0 4.3 3 0 0 3 3 3 0 Phage T7 capsid assembly protein Piwi PF02171.17 VBB27585.1 - 4.3e-115 384.1 0.0 7.6e-115 383.3 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 VBB27585.1 - 5.2e-34 116.4 1.0 2e-33 114.5 0.2 2.5 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 VBB27585.1 - 1.5e-26 93.6 0.0 3.9e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 VBB27585.1 - 4.2e-22 77.6 0.1 9.5e-22 76.4 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 VBB27585.1 - 1.6e-20 73.3 0.8 7.3e-20 71.2 0.8 2.1 1 1 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 VBB27585.1 - 6.8e-14 51.9 0.0 2.6e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain Motile_Sperm PF00635.26 VBB27585.1 - 5.2e-10 39.1 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Sybindin PF04099.12 VBB27587.1 - 6.4e-31 107.2 0.7 7.2e-31 107.0 0.7 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 VBB27587.1 - 0.0018 18.4 0.1 0.0021 18.2 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF1831 PF08866.10 VBB27587.1 - 0.041 14.4 0.6 0.52 10.8 0.0 2.1 1 1 1 2 2 2 0 Putative amino acid metabolism EB PF01683.18 VBB27588.1 - 8.6e-06 26.0 44.2 5.2e-05 23.4 18.5 13.1 6 2 4 11 11 11 3 EB module Arm PF00514.23 VBB27589.1 - 6.5e-21 73.6 11.7 0.00068 19.6 0.0 7.8 8 1 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 VBB27589.1 - 3.7e-08 33.7 1.0 0.0025 18.3 0.7 4.9 5 1 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 VBB27589.1 - 0.00012 22.4 0.8 1.6 9.2 1.1 4.4 1 1 1 3 3 3 1 HEAT repeats RICTOR_V PF14668.6 VBB27589.1 - 0.00043 20.5 0.8 1.6 9.1 0.0 5.0 5 1 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 VBB27589.1 - 0.17 12.6 8.0 27 5.8 0.4 5.3 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat Folate_carrier PF01770.18 VBB27590.1 - 2e-88 296.9 12.7 2.3e-88 296.7 12.7 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 VBB27590.1 - 1.5e-08 34.0 1.8 1.8e-08 33.7 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Col_cuticle_N PF01484.17 VBB27590.1 - 0.79 9.8 0.1 0.79 9.8 0.1 2.7 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF485 PF04341.12 VBB27590.1 - 0.94 9.5 8.5 0.58 10.1 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 P4Ha_N PF08336.11 VBB27591.1 - 1.6e-24 86.4 0.4 5.8e-24 84.6 0.4 2.0 1 1 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 VBB27591.1 - 2.2e-16 60.5 0.0 4.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 VBB27591.1 - 1.7e-08 34.8 0.0 3.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 VBB27591.1 - 2.6e-05 24.0 3.1 0.00025 20.9 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB27591.1 - 0.0039 17.2 0.1 0.0086 16.1 0.1 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 VBB27591.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 VBB27591.1 - 0.02 15.5 0.6 0.1 13.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB27591.1 - 0.071 13.3 0.3 0.48 10.7 0.1 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 VBB27591.1 - 0.087 13.3 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Complex1_30kDa PF00329.19 VBB27593.1 - 4.6e-41 140.3 0.0 6.8e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2087 PF09860.9 VBB27593.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) TLD PF07534.16 VBB27594.1 - 1.4e-29 103.1 0.8 2.1e-29 102.5 0.8 1.3 1 0 0 1 1 1 1 TLD Rad21_Rec8_N PF04825.13 VBB27594.1 - 0.13 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein HSBP1 PF06825.12 VBB27595.1 - 6.9e-26 89.9 5.6 1e-25 89.3 5.6 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 EspB PF05802.11 VBB27595.1 - 0.00013 22.0 2.4 0.00015 21.8 2.4 1.1 1 0 0 1 1 1 1 Enterobacterial EspB protein CLZ PF16526.5 VBB27595.1 - 0.0031 17.8 0.8 0.004 17.5 0.8 1.3 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 VBB27595.1 - 0.012 16.2 1.2 0.19 12.3 0.3 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 KxDL PF10241.9 VBB27595.1 - 0.055 13.7 0.1 0.083 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein TrbI PF03743.14 VBB27595.1 - 0.058 13.2 0.2 0.07 13.0 0.2 1.1 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF883 PF05957.13 VBB27595.1 - 0.066 13.8 0.3 0.085 13.5 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) BLOC1_2 PF10046.9 VBB27595.1 - 0.067 13.5 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Matrilin_ccoil PF10393.9 VBB27595.1 - 0.067 13.1 1.4 0.22 11.4 0.4 2.3 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Prefoldin_3 PF13758.6 VBB27595.1 - 0.11 12.6 1.3 0.12 12.4 1.3 1.3 1 1 0 1 1 1 0 Prefoldin subunit Allexi_40kDa PF05549.11 VBB27595.1 - 0.14 11.6 0.2 0.14 11.6 0.2 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF948 PF06103.11 VBB27595.1 - 0.23 11.7 0.8 0.62 10.4 0.8 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Trimer_CC PF08954.11 VBB27595.1 - 0.73 9.4 4.4 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Trimerisation motif Ank_4 PF13637.6 VBB27596.1 - 1.9e-14 53.8 0.0 1.2e-06 28.9 0.0 3.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB27596.1 - 3.4e-14 53.2 2.5 4.5e-06 27.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB27596.1 - 9.9e-14 51.2 0.5 8.8e-08 32.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB27596.1 - 1.1e-12 47.0 1.3 0.00034 20.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat KH_6 PF15985.5 VBB27596.1 - 1.3e-12 47.8 0.3 4.2e-11 43.0 0.1 2.6 2 0 0 2 2 2 1 KH domain Ank PF00023.30 VBB27596.1 - 1.9e-10 40.7 0.1 0.0013 19.0 0.0 4.5 3 0 0 3 3 3 3 Ankyrin repeat LRR_4 PF12799.7 VBB27596.1 - 3.3e-05 24.2 27.2 0.016 15.6 1.0 5.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) TPR_12 PF13424.6 VBB27596.1 - 0.0034 17.6 3.0 0.019 15.2 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat LRR_8 PF13855.6 VBB27596.1 - 0.031 14.0 21.8 0.019 14.8 2.8 4.4 2 2 1 3 3 3 0 Leucine rich repeat RPN7 PF10602.9 VBB27597.1 - 0.00027 20.7 0.6 0.0028 17.4 0.1 2.1 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_1 PF00515.28 VBB27597.1 - 0.00052 19.7 0.6 0.0067 16.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB27597.1 - 0.0035 17.3 4.5 0.0079 16.2 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB27597.1 - 0.0036 17.6 3.6 0.011 16.1 1.4 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB27597.1 - 0.0042 17.2 5.8 0.0053 16.9 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat Foie-gras_1 PF11817.8 VBB27597.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 Foie gras liver health family 1 Exonuc_VII_S PF02609.16 VBB27597.1 - 1.3 9.1 5.3 13 6.0 0.5 3.1 3 0 0 3 3 3 0 Exonuclease VII small subunit CS PF04969.16 VBB27598.1 - 7.3e-18 65.4 0.4 1.7e-17 64.2 0.4 1.7 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 VBB27598.1 - 1.9e-11 43.8 0.0 1.2e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 N-terminal conserved domain of Nudc. PHC2_SAM_assoc PF16616.5 VBB27598.1 - 0.31 11.9 6.7 0.7 10.7 6.7 1.6 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Presenilin PF01080.17 VBB27598.1 - 0.77 8.5 6.8 1.3 7.7 6.8 1.3 1 0 0 1 1 1 0 Presenilin Clat_adaptor_s PF01217.20 VBB27599.1 - 1.1e-53 181.0 2.6 1.4e-53 180.7 2.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PD40 PF07676.12 VBB27600.1 - 1.9e-49 164.7 31.7 1.1e-08 34.8 0.5 11.1 11 0 0 11 11 11 10 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 VBB27600.1 - 1.7e-08 33.6 0.0 0.015 14.1 0.0 5.6 5 2 1 6 6 6 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Laminin_N PF00055.17 VBB27601.1 - 2e-68 230.5 0.4 2e-68 230.5 0.4 2.9 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) NTR PF01759.21 VBB27601.1 - 1.2e-21 76.6 0.1 2.1e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 VBB27601.1 - 6.1e-20 71.1 73.8 4.1e-10 39.6 14.7 4.9 6 0 0 6 6 6 3 Laminin EGF domain F5_F8_type_C PF00754.25 VBB27601.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_63 PF03200.16 VBB27602.1 - 4.7e-182 606.2 1.4 6.6e-182 605.6 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 VBB27602.1 - 4.7e-29 102.1 0.2 8.4e-29 101.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 VBB27602.1 - 0.00011 21.3 0.1 0.00082 18.4 0.1 2.2 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 VBB27602.1 - 0.02 13.7 2.0 0.088 11.6 0.7 2.3 1 1 1 2 2 2 0 Trehalase Bac_rhamnosid6H PF17389.2 VBB27602.1 - 0.026 13.8 0.1 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain LMF1 PF06762.14 VBB27603.1 - 1.6e-90 304.4 11.1 9.4e-67 226.0 3.8 2.2 1 1 1 2 2 2 2 Lipase maturation factor Thioredoxin PF00085.20 VBB27604.1 - 1.2e-08 34.9 0.0 0.0075 16.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin 2-Hacid_dh_C PF02826.19 VBB27606.1 - 6.3e-48 162.5 0.0 1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 VBB27606.1 - 3.4e-21 75.3 0.2 3.4e-14 52.7 0.5 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 VBB27606.1 - 8.3e-05 22.8 0.0 0.00042 20.5 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RAMP4 PF06624.12 VBB27607.1 - 0.004 17.2 0.1 0.008 16.2 0.1 1.5 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 MLANA PF14991.6 VBB27607.1 - 0.032 14.5 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A RTA1 PF04479.13 VBB27607.1 - 0.04 13.5 0.2 0.049 13.2 0.2 1.1 1 0 0 1 1 1 0 RTA1 like protein Saf_2TM PF18303.1 VBB27607.1 - 0.047 13.3 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Chromate_transp PF02417.15 VBB27607.1 - 0.048 13.8 0.1 0.057 13.6 0.1 1.1 1 0 0 1 1 1 0 Chromate transporter PDR_assoc PF08370.11 VBB27607.1 - 0.052 13.3 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Plant PDR ABC transporter associated DUF2207 PF09972.9 VBB27607.1 - 0.059 12.1 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Comm PF15957.5 VBB27607.1 - 0.084 13.2 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Commissureless zf-LITAF-like PF10601.9 VBB27607.1 - 0.091 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Orf78 PF06024.12 VBB27607.1 - 0.17 12.2 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TMEM132D_C PF15706.5 VBB27607.1 - 0.19 11.5 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Stevor PF17410.2 VBB27607.1 - 0.22 11.0 0.2 0.28 10.7 0.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VEFS-Box PF09733.9 VBB27609.1 - 2.1e-16 59.9 2.1 6.2e-16 58.5 2.1 1.8 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Ras PF00071.22 VBB27610.1 - 3.1e-33 114.7 0.4 5.6e-33 113.8 0.4 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB27610.1 - 4.5e-13 49.5 0.2 1e-12 48.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Claudin_2 PF13903.6 VBB27610.1 - 7.7e-13 48.6 2.5 1.1e-12 48.1 0.7 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Arf PF00025.21 VBB27610.1 - 0.0028 17.1 0.1 0.012 15.1 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Tetraspanin PF00335.20 VBB27610.1 - 0.015 15.0 0.8 0.043 13.5 0.3 2.0 2 0 0 2 2 2 0 Tetraspanin family SRPRB PF09439.10 VBB27610.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.25 VBB27611.1 - 2.7e-133 443.3 0.0 9.5e-67 225.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27611.1 - 5e-65 219.3 0.0 1.2e-32 113.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 VBB27611.1 - 4e-12 46.1 0.0 4.6e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 VBB27611.1 - 2.1e-11 44.2 0.0 0.0021 18.0 0.0 3.8 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 VBB27611.1 - 8.4e-10 38.3 0.5 3.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB27611.1 - 8.7e-09 34.8 1.5 0.00027 20.0 0.5 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 VBB27611.1 - 2.1e-06 28.3 0.3 6.4e-06 26.8 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.22 VBB27611.1 - 6.8e-06 25.8 0.9 0.025 14.2 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 VBB27611.1 - 1.6e-05 23.9 0.0 0.022 13.6 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase Choline_kinase PF01633.20 VBB27611.1 - 0.0073 15.9 0.0 0.045 13.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 VBB27611.1 - 0.0082 15.7 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 VBB27611.1 - 0.078 12.6 0.6 36 3.9 0.0 3.2 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF1679 PF07914.11 VBB27611.1 - 0.085 11.7 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Maf PF02545.14 VBB27612.1 - 1.1e-52 178.3 0.0 1.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein DUF2048 PF09752.9 VBB27613.1 - 1.3e-99 333.7 0.0 1.5e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Peptidase_S15 PF02129.18 VBB27613.1 - 0.0037 16.9 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 VBB27613.1 - 0.029 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 VBB27613.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Cytochrom_C1 PF02167.15 VBB27614.1 - 1.9e-81 273.0 0.0 2.2e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 VBB27614.1 - 0.0032 17.8 0.1 0.0074 16.6 0.1 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 VBB27614.1 - 0.0046 18.1 0.0 0.018 16.1 0.0 2.0 2 1 0 2 2 2 1 Cytochrome c RRM_1 PF00076.22 VBB27615.1 - 1.2e-20 73.0 0.0 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 VBB27615.1 - 0.00067 19.9 1.8 2 8.6 0.0 3.7 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 VBB27615.1 - 0.0072 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif G-alpha PF00503.20 VBB27618.1 - 7.9e-121 403.5 5.1 9.4e-121 403.3 5.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB27618.1 - 7.2e-15 54.9 2.5 2.4e-11 43.4 0.1 2.9 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB27618.1 - 8.5e-06 25.3 0.3 0.002 17.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 VBB27618.1 - 0.0052 16.2 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 VBB27618.1 - 0.0056 16.9 0.0 1.3 9.2 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase DUF3016 PF11454.8 VBB27618.1 - 0.051 13.3 0.5 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) AAA_29 PF13555.6 VBB27618.1 - 0.064 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 VBB27618.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 VBB27618.1 - 0.15 12.2 0.0 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRCC PF10253.9 VBB27619.1 - 1.6e-22 81.3 1.2 2e-21 77.8 0.8 2.3 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Glyco_transf_49 PF13896.6 VBB27621.1 - 7.6e-52 176.7 2.5 2e-43 149.0 0.4 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 VBB27621.1 - 1.3e-19 70.8 2.2 2.5e-19 69.9 2.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 VBB27621.1 - 0.0001 21.9 4.4 0.00018 21.0 4.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_34 PF05637.12 VBB27621.1 - 0.0093 15.7 1.4 0.016 15.0 1.4 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Sigma_reg_N PF13800.6 VBB27621.1 - 0.1 12.9 1.3 0.26 11.6 1.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TDP43_N PF18694.1 VBB27622.1 - 2e-15 56.4 0.0 5e-12 45.5 0.0 2.5 1 1 1 2 2 2 2 Transactive response DNA-binding protein N-terminal domain Tnp_P_element_C PF12596.8 VBB27623.1 - 0.016 15.7 0.0 0.055 14.0 0.0 1.9 1 0 0 1 1 1 0 87kDa Transposase DUF2198 PF09964.9 VBB27623.1 - 0.023 14.7 1.3 0.059 13.4 1.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF550 PF04447.12 VBB27623.1 - 0.059 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Ephrin_rec_like PF07699.13 VBB27625.1 - 4.5e-47 157.6 123.5 1.8e-10 40.4 6.4 12.0 9 2 1 11 11 11 7 Putative ephrin-receptor like HYR PF02494.16 VBB27625.1 - 3e-13 49.9 0.3 6.9e-10 39.1 0.1 3.2 2 0 0 2 2 2 2 HYR domain Sushi PF00084.20 VBB27625.1 - 4.7e-10 39.9 8.5 5.7e-06 26.8 0.7 14.6 14 2 2 16 16 16 7 Sushi repeat (SCR repeat) EGF PF00008.27 VBB27625.1 - 4.5e-07 30.1 181.8 4.2e-05 23.7 7.4 16.2 16 0 0 16 16 16 9 EGF-like domain EGF_CA PF07645.15 VBB27625.1 - 6.5e-07 29.5 3.3 6.5e-07 29.5 3.3 20.1 19 3 4 23 23 23 3 Calcium-binding EGF domain Ldl_recept_a PF00057.18 VBB27625.1 - 0.00029 21.0 11.0 0.00029 21.0 11.0 11.8 13 0 0 13 13 13 1 Low-density lipoprotein receptor domain class A hEGF PF12661.7 VBB27625.1 - 0.00077 20.0 4.1 0.00077 20.0 4.1 16.1 15 0 0 15 15 15 6 Human growth factor-like EGF Laminin_G_3 PF13385.6 VBB27625.1 - 0.001 19.2 0.1 0.06 13.5 0.1 2.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily I-set PF07679.16 VBB27625.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain RhoGEF PF00621.20 VBB27626.1 - 3e-38 131.9 10.3 5.4e-38 131.0 7.1 2.7 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.29 VBB27626.1 - 2.6e-11 44.0 0.0 0.00023 21.6 0.0 3.2 3 0 0 3 3 3 2 PH domain FYVE PF01363.21 VBB27626.1 - 1e-05 25.6 14.7 3.1e-05 24.0 14.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH_13 PF16652.5 VBB27626.1 - 0.00049 19.9 0.6 0.77 9.6 0.1 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain KMP11 PF03037.16 VBB27626.1 - 1.4 9.8 4.7 7.3 7.5 0.1 3.5 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 zf-C3HC4_2 PF13923.6 VBB27626.1 - 6.4 6.7 9.3 4.2 7.3 6.5 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 VBB27626.1 - 9.7 6.4 21.1 0.02 15.1 8.2 3.2 4 0 0 4 4 4 0 FYVE-type zinc finger ShK PF01549.24 VBB27627.1 - 1.9e-08 34.7 8.1 3.8e-08 33.7 8.1 1.5 1 0 0 1 1 1 1 ShK domain-like EGF_2 PF07974.13 VBB27627.1 - 0.00034 20.9 5.0 0.00034 20.9 5.0 2.5 2 0 0 2 2 2 1 EGF-like domain DUF1794 PF08768.11 VBB27627.1 - 0.0042 17.1 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) hEGF PF12661.7 VBB27627.1 - 9.6 7.0 11.5 0.81 10.4 3.7 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF NAD_binding_6 PF08030.12 VBB27628.1 - 1.6e-21 77.0 2.0 1.4e-20 74.0 2.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 VBB27628.1 - 3.4e-16 59.3 0.0 8.9e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 VBB27628.1 - 8.7e-15 54.9 9.0 8.7e-15 54.9 9.0 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_8 PF13833.6 VBB27628.1 - 0.011 15.6 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 VBB27628.1 - 0.028 14.9 1.6 0.083 13.3 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 VBB27628.1 - 0.12 12.0 1.3 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 VBB27628.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain HSP20 PF00011.21 VBB27629.1 - 5.2e-15 55.4 0.2 6.3e-15 55.2 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB27629.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Cypo_polyhedrin PF05865.11 VBB27629.1 - 0.12 11.7 0.0 0.45 9.9 0.0 1.7 1 1 0 1 1 1 0 Cypovirus polyhedrin protein Thioredoxin PF00085.20 VBB27630.1 - 4.1e-94 309.4 6.7 6.5e-31 106.4 0.0 4.7 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.6 VBB27630.1 - 2.6e-28 99.2 14.5 1.5e-17 64.1 0.9 4.6 4 1 1 5 5 5 4 Thioredoxin-like domain Thioredoxin_8 PF13905.6 VBB27630.1 - 1.4e-15 57.4 6.5 9.2e-05 22.7 0.0 6.7 5 3 2 7 7 7 3 Thioredoxin-like Thioredoxin_2 PF13098.6 VBB27630.1 - 4.5e-14 52.8 7.0 0.00098 19.6 0.1 5.6 3 3 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 VBB27630.1 - 1.2e-11 44.6 0.0 0.0027 17.9 0.0 3.7 3 0 0 3 3 3 3 Thioredoxin-like OST3_OST6 PF04756.13 VBB27630.1 - 1.9e-11 43.9 0.3 0.0061 16.0 0.0 3.6 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 VBB27630.1 - 2.2e-10 40.1 5.4 1.8e-08 33.9 3.4 2.9 2 1 1 3 3 3 1 Calsequestrin AhpC-TSA PF00578.21 VBB27630.1 - 3.4e-10 39.9 4.4 0.0018 18.2 0.0 4.4 3 1 1 4 4 4 3 AhpC/TSA family Thioredoxin_3 PF13192.6 VBB27630.1 - 2.3e-06 27.6 0.0 0.35 11.0 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.6 VBB27630.1 - 9.6e-06 25.6 0.0 1.2 9.0 0.0 3.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 VBB27630.1 - 1.6e-05 25.1 1.0 0.75 9.9 0.0 5.0 4 1 1 5 5 5 1 Thioredoxin Thioredoxin_5 PF13743.6 VBB27630.1 - 8e-05 22.4 2.6 4.7 6.8 0.0 5.2 3 3 3 6 6 6 1 Thioredoxin Redoxin PF08534.10 VBB27630.1 - 0.00014 21.6 4.5 2.1 8.0 0.0 4.4 4 0 0 4 4 4 1 Redoxin Thioredoxin_9 PF14595.6 VBB27630.1 - 0.00061 19.6 0.0 0.97 9.2 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin HyaE PF07449.11 VBB27630.1 - 0.0061 16.5 0.0 8.1 6.5 0.0 3.2 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 VBB27630.1 - 0.018 14.8 0.6 59 3.4 0.0 4.4 3 2 1 4 4 4 0 DSBA-like thioredoxin domain UCH_1 PF13423.6 VBB27630.1 - 0.037 13.6 0.3 5.3 6.5 0.0 2.9 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Glutaredoxin PF00462.24 VBB27630.1 - 0.12 12.7 6.9 8.9 6.6 0.0 4.4 4 1 0 4 4 4 0 Glutaredoxin Flavodoxin_3 PF12641.7 VBB27630.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain IBR PF01485.21 VBB27631.1 - 4.6e-05 23.6 4.7 4.6e-05 23.6 4.7 3.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain PUF PF00806.19 VBB27632.1 - 5.1e-36 120.3 3.1 0.00016 21.2 0.0 7.8 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Trypsin PF00089.26 VBB27632.1 - 4.7e-15 56.0 0.0 9.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 VBB27632.1 - 0.0013 19.6 0.0 0.0037 18.2 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Fez1 PF06818.15 VBB27633.1 - 0.0018 18.8 17.4 0.0018 18.8 17.4 4.0 1 1 2 3 3 3 1 Fez1 ecTbetaR2 PF08917.10 VBB27633.1 - 0.48 10.4 3.5 0.37 10.7 1.2 1.9 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain DPM3 PF08285.11 VBB27633.1 - 3 8.1 4.1 25 5.1 0.3 2.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PDZ_2 PF13180.6 VBB27634.1 - 5.4e-05 23.4 0.0 0.13 12.6 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB27634.1 - 0.019 14.8 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 PDZ domain Tricorn_PDZ PF14685.6 VBB27634.1 - 0.18 11.8 0.0 1.4 9.0 0.0 2.4 3 0 0 3 3 3 0 Tricorn protease PDZ domain Cmc1 PF08583.10 VBB27635.1 - 0.00017 21.6 2.9 0.00069 19.6 0.6 2.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 VBB27635.1 - 0.025 14.7 1.4 0.28 11.4 0.1 2.6 2 1 0 2 2 2 0 CHCH domain CX9C PF16860.5 VBB27635.1 - 0.043 13.8 1.2 0.043 13.8 1.2 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Curto_V2 PF07325.11 VBB27635.1 - 0.06 13.2 0.8 1.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Curtovirus V2 protein Hist_deacetyl PF00850.19 VBB27638.1 - 2e-83 280.4 1.1 1.6e-81 274.2 0.0 2.2 2 0 0 2 2 2 2 Histone deacetylase domain DUF4644 PF15486.6 VBB27638.1 - 0.016 15.0 0.3 0.016 15.0 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4644) CSRNP_N PF16019.5 VBB27638.1 - 0.62 9.9 5.3 1.3 8.9 5.3 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus MIP PF00230.20 VBB27639.1 - 4.4e-38 131.3 4.7 5.8e-38 130.8 4.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein ArAE_2_N PF10337.9 VBB27639.1 - 1.2 8.1 6.1 6.3 5.7 0.2 2.2 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal PTPLA PF04387.14 VBB27640.1 - 2.8e-23 82.5 0.9 4.7e-23 81.7 0.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Pkinase PF00069.25 VBB27641.1 - 2.6e-70 236.8 0.0 3.5e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27641.1 - 7.4e-51 172.9 0.0 1.1e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB27641.1 - 0.00023 20.1 0.0 0.00055 18.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 VBB27641.1 - 0.00053 19.4 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 VBB27641.1 - 0.0017 18.0 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 VBB27641.1 - 0.062 12.2 0.1 0.36 9.7 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 VBB27641.1 - 0.073 13.0 0.0 4.6 7.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family A_deaminase PF00962.22 VBB27642.1 - 1.7e-67 228.1 0.1 8.8e-67 225.8 0.1 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF4457 PF14652.6 VBB27644.1 - 2.6e-102 342.4 0.1 4.9e-72 242.9 0.1 5.0 2 2 1 4 4 4 4 Domain of unknown function (DUF4457) XRCC1_N PF01834.16 VBB27644.1 - 0.12 12.4 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 XRCC1 N terminal domain Cu2_monoox_C PF03712.15 VBB27646.1 - 2.6e-39 134.3 0.0 5.2e-39 133.3 0.0 1.5 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 VBB27646.1 - 7.5e-26 90.9 0.1 1.8e-25 89.7 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Piwi PF02171.17 VBB27647.1 - 5.6e-88 295.1 0.1 2e-87 293.3 0.0 1.8 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 VBB27647.1 - 7.4e-09 35.5 0.8 1.4e-08 34.7 0.8 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 VBB27647.1 - 1.5e-06 27.7 0.0 4.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 VBB27647.1 - 2.9e-06 27.9 0.0 6.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 VBB27647.1 - 0.0074 16.6 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain MFP2b PF12150.8 VBB27648.1 - 6.5e-150 499.2 0.1 7.4e-150 499.0 0.1 1.0 1 0 0 1 1 1 1 Cytosolic motility protein Neur_chan_LBD PF02931.23 VBB27649.1 - 4.8e-64 215.8 3.3 6.6e-64 215.3 3.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB27649.1 - 1.9e-62 211.4 1.3 2.4e-62 211.1 1.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2207 PF09972.9 VBB27649.1 - 0.021 13.6 0.5 0.19 10.5 0.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Spo7 PF03907.13 VBB27649.1 - 4.8 6.6 6.8 0.63 9.5 1.0 2.1 2 0 0 2 2 2 0 Spo7-like protein PK PF00224.21 VBB27650.1 - 7.8e-106 353.9 0.9 9.8e-106 353.5 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 VBB27650.1 - 5.6e-33 113.7 1.2 1e-32 112.8 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 VBB27650.1 - 1.5e-07 30.8 0.2 2.5e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Acetyltransf_10 PF13673.7 VBB27651.1 - 1.4e-07 31.5 0.0 4e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB27651.1 - 6.6e-07 29.6 0.0 3.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_18 PF18014.1 VBB27651.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 VBB27651.1 - 7.9e-05 23.0 0.1 0.00029 21.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain HEAT PF02985.22 VBB27653.1 - 2e-11 43.1 0.1 0.81 10.1 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 VBB27653.1 - 3.5e-07 30.5 0.0 0.0002 21.7 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats Cnd1 PF12717.7 VBB27653.1 - 7e-07 29.4 0.0 0.0012 18.9 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 VBB27653.1 - 0.0026 17.1 0.1 1.9 7.7 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 VBB27653.1 - 0.0037 16.7 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.6 VBB27653.1 - 0.029 14.9 3.9 25 5.5 0.1 4.7 4 2 1 5 5 5 0 HEAT-like repeat Adaptin_N PF01602.20 VBB27653.1 - 0.13 10.8 0.1 0.53 8.8 0.1 1.8 1 1 0 1 1 1 0 Adaptin N terminal region PDZ PF00595.24 VBB27654.1 - 7.5e-13 48.6 4.7 2.8e-06 27.6 1.2 2.5 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB27654.1 - 6.1e-11 42.5 2.3 3.4e-05 24.1 0.1 2.6 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 VBB27654.1 - 1.1e-08 34.8 1.3 4.1e-05 23.3 0.1 2.6 3 0 0 3 3 3 2 PDZ domain PDZ_4 PF17816.1 VBB27654.1 - 2.9e-05 24.4 1.3 0.033 14.6 0.0 2.9 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 VBB27654.1 - 0.00038 20.4 0.8 0.65 10.0 0.1 2.6 1 1 2 3 3 3 2 Tricorn protease PDZ domain CD36 PF01130.21 VBB27655.1 - 4.8e-111 371.6 2.8 5.5e-111 371.4 2.8 1.0 1 0 0 1 1 1 1 CD36 family UPF0239 PF06783.11 VBB27655.1 - 0.19 11.9 0.1 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) RNA_pol_Rpb2_6 PF00562.28 VBB27656.1 - 1.5e-123 412.7 0.8 6.2e-123 410.7 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 VBB27656.1 - 8.7e-48 162.5 0.0 9e-46 155.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 VBB27656.1 - 4.8e-35 119.8 0.6 1.3e-34 118.5 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 VBB27656.1 - 2.1e-25 89.5 0.7 8.5e-25 87.5 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 VBB27656.1 - 3.1e-23 81.8 1.3 6.5e-23 80.8 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 VBB27656.1 - 1.3e-20 73.4 0.0 3e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 VBB27656.1 - 5.3e-09 36.5 1.0 2e-08 34.7 0.5 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Glyco_hydro_2_C PF02836.17 VBB27657.1 - 1.2e-70 238.0 0.2 4.3e-70 236.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 VBB27657.1 - 2.2e-18 66.8 0.9 4.9e-18 65.6 0.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 VBB27657.1 - 2.1e-05 25.1 0.0 4.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Frataxin_Cyay PF01491.16 VBB27658.1 - 6.9e-32 109.7 0.1 1.3e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 Frataxin-like domain ADH_zinc_N_2 PF13602.6 VBB27658.1 - 6e-12 46.8 0.0 1.3e-11 45.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 VBB27658.1 - 1.3e-07 31.7 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 VBB27658.1 - 1.7e-07 31.0 0.6 5.5e-07 29.5 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 VBB27658.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0261 PF06792.11 VBB27658.1 - 0.014 14.4 0.0 0.47 9.3 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0261) Sacchrp_dh_NADP PF03435.18 VBB27658.1 - 0.015 15.5 0.0 0.047 14.0 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 VBB27658.1 - 0.037 14.7 0.0 0.073 13.7 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Bac_small_YrzI PF09501.10 VBB27658.1 - 0.063 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DapB_N PF01113.20 VBB27658.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 VBB27658.1 - 0.18 11.8 0.0 0.76 9.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L13 PF00572.18 VBB27660.1 - 3.6e-35 121.0 0.0 4.9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 DHC_N2 PF08393.13 VBB27660.1 - 0.093 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Mito_carr PF00153.27 VBB27661.1 - 5.1e-36 122.5 2.6 1.2e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA PF00004.29 VBB27662.1 - 3.3e-42 144.0 0.0 9.5e-42 142.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 VBB27662.1 - 3.5e-19 68.5 0.4 8.1e-19 67.3 0.4 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 VBB27662.1 - 1.6e-09 37.4 0.4 3.7e-09 36.2 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 VBB27662.1 - 5.5e-07 29.7 0.8 2.2e-06 27.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB27662.1 - 7.6e-06 26.4 0.3 0.0033 17.8 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 VBB27662.1 - 1.3e-05 25.0 0.1 4e-05 23.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 VBB27662.1 - 3.1e-05 24.2 0.0 0.00018 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 VBB27662.1 - 0.00031 21.0 2.9 0.01 16.1 0.0 3.2 3 1 1 4 4 3 1 AAA domain DUF815 PF05673.13 VBB27662.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 VBB27662.1 - 0.0013 18.2 0.2 0.0038 16.6 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 VBB27662.1 - 0.007 16.9 0.0 0.025 15.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 VBB27662.1 - 0.007 15.9 0.0 0.018 14.5 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 VBB27662.1 - 0.013 15.7 0.0 0.042 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 VBB27662.1 - 0.015 15.0 0.2 0.05 13.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 VBB27662.1 - 0.016 14.6 1.4 0.096 12.0 0.0 2.4 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 VBB27662.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 VBB27662.1 - 0.017 14.7 0.5 0.1 12.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 VBB27662.1 - 0.028 14.3 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 VBB27662.1 - 0.028 13.9 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 VBB27662.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 VBB27662.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF812 PF05667.11 VBB27662.1 - 0.049 12.5 5.2 0.073 12.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sigma54_activat PF00158.26 VBB27662.1 - 0.052 13.2 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 VBB27662.1 - 0.068 13.1 0.6 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain DUF1640 PF07798.11 VBB27662.1 - 0.069 13.2 4.5 0.14 12.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_30 PF13604.6 VBB27662.1 - 0.089 12.5 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 VBB27662.1 - 0.093 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 VBB27662.1 - 0.12 12.4 0.2 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 VBB27662.1 - 0.12 12.9 0.2 1.1 9.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter TsaE PF02367.17 VBB27662.1 - 0.13 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 VBB27662.1 - 0.15 11.7 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_19 PF13245.6 VBB27662.1 - 0.21 11.9 2.1 0.24 11.7 0.2 2.1 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 VBB27662.1 - 0.3 10.8 0.1 0.3 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain ribosomal_L24 PF17136.4 VBB27664.1 - 2.8e-07 30.8 0.0 7.3e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 VBB27664.1 - 5e-07 29.4 1.7 5e-07 29.4 1.7 1.9 2 0 0 2 2 2 1 KOW motif UQ_con PF00179.26 VBB27665.1 - 7.8e-53 177.9 0.0 9.5e-53 177.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB27665.1 - 0.04 13.6 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 VBB27665.1 - 0.042 14.1 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 VBB27665.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 UEV domain Zip PF02535.22 VBB27666.1 - 1.7e-32 113.0 1.1 2.2e-32 112.6 1.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Spermine_synth PF01564.17 VBB27667.1 - 4.3e-13 49.1 0.6 7.8e-13 48.2 0.6 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_15 PF09445.10 VBB27667.1 - 0.0046 16.5 1.9 5.6 6.5 0.6 3.1 2 1 0 2 2 2 2 RNA cap guanine-N2 methyltransferase MTS PF05175.14 VBB27667.1 - 0.014 15.0 0.1 0.032 13.8 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 VBB27667.1 - 0.048 13.0 0.3 0.079 12.2 0.3 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_25 PF13649.6 VBB27667.1 - 0.085 13.6 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PDZ PF00595.24 VBB27668.1 - 8.1e-19 67.8 1.2 4.4e-18 65.4 0.7 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 VBB27668.1 - 5.9e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 VBB27668.1 - 2.3e-10 40.9 1.6 3.7e-05 24.2 0.1 3.0 3 0 0 3 3 3 2 PH domain PH_17 PF18012.1 VBB27668.1 - 8.7e-08 31.8 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PDZ_2 PF13180.6 VBB27668.1 - 3.6e-06 27.2 0.2 1e-05 25.7 0.2 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 VBB27668.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Aminotran_3 PF00202.21 VBB27668.1 - 0.22 10.2 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Motile_Sperm PF00635.26 VBB27669.1 - 1.7e-18 66.4 0.9 3.5e-18 65.4 0.9 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Roc PF08477.13 VBB27670.1 - 4.4e-05 23.7 0.0 6.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB27670.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Ras family Ras PF00071.22 VBB27671.1 - 4e-49 166.3 1.9 3.5e-47 160.0 1.9 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB27671.1 - 3.6e-24 85.3 1.3 6.4e-17 61.9 0.1 2.5 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB27671.1 - 1.1e-12 47.8 0.4 2.7e-12 46.5 0.4 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB27671.1 - 3.5e-05 23.8 0.5 0.0071 16.3 0.3 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 VBB27671.1 - 7.8e-05 22.3 0.0 0.00018 21.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 VBB27671.1 - 0.00056 19.7 0.0 0.00098 18.9 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 VBB27671.1 - 0.0013 18.1 0.2 0.019 14.3 0.0 2.2 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 VBB27671.1 - 0.0029 17.1 0.2 0.18 11.3 0.1 2.2 1 1 1 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 VBB27671.1 - 0.022 14.8 0.1 0.23 11.6 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 VBB27671.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain GDP_Man_Dehyd PF16363.5 VBB27672.1 - 5.4e-69 233.1 0.0 6.1e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 VBB27672.1 - 4.9e-55 186.6 0.0 6e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 VBB27672.1 - 6.9e-21 74.6 0.0 7.4e-20 71.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 VBB27672.1 - 1.1e-16 60.7 0.1 1.4e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 VBB27672.1 - 1.8e-13 50.3 0.1 9.4e-13 47.9 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 VBB27672.1 - 4e-09 36.0 0.0 6.2e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 VBB27672.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 KR domain Metallophos PF00149.28 VBB27673.1 - 4.3e-35 122.1 0.8 8.1e-35 121.2 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB27673.1 - 0.012 16.0 0.2 0.033 14.6 0.2 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 VBB27673.1 - 0.058 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ras PF00071.22 VBB27674.1 - 6.7e-53 178.6 0.0 7.6e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB27674.1 - 1.7e-21 76.6 0.0 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB27674.1 - 2.8e-08 33.4 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB27674.1 - 0.0023 17.5 0.0 0.0042 16.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 VBB27674.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CtaG_Cox11 PF04442.14 VBB27676.1 - 3.4e-50 170.0 0.1 4.6e-50 169.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 GDP_Man_Dehyd PF16363.5 VBB27677.1 - 3.6e-57 194.2 0.2 2e-56 191.8 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 VBB27677.1 - 1.5e-48 165.3 0.1 2.1e-48 164.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 VBB27677.1 - 1.5e-09 37.4 0.3 9.5e-06 25.0 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 VBB27677.1 - 1.3e-08 34.2 0.0 3.6e-08 32.7 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 VBB27677.1 - 2.4e-08 33.4 0.0 3.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 VBB27677.1 - 1.2e-07 31.1 0.2 0.0042 16.3 0.2 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Med17 PF10156.9 VBB27677.1 - 0.016 13.9 0.6 0.026 13.3 0.6 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex adh_short PF00106.25 VBB27677.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase YabA PF06156.13 VBB27677.1 - 1.7 9.4 3.7 1.2 9.8 1.4 1.8 2 0 0 2 2 2 0 Initiation control protein YabA zf_CCCH_4 PF18345.1 VBB27678.1 - 2.1e-06 27.6 4.2 4.1e-06 26.7 4.2 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 VBB27678.1 - 0.0001 23.0 0.1 0.0007 20.3 0.0 2.5 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 VBB27678.1 - 0.00014 21.5 1.8 0.00029 20.5 1.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 VBB27678.1 - 0.0017 18.2 0.4 0.0038 17.1 0.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UPF0086 PF01868.16 VBB27679.1 - 1.7e-12 47.1 0.0 3.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 MFP2b PF12150.8 VBB27680.1 - 4.7e-07 29.4 0.0 5.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Cytosolic motility protein GMP_PDE_delta PF05351.11 VBB27680.1 - 0.02 15.0 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit Syja_N PF02383.18 VBB27681.1 - 4.7e-75 252.9 0.2 5.2e-74 249.4 0.0 2.1 2 0 0 2 2 2 1 SacI homology domain RNA_pol_3_Rpc31 PF11705.8 VBB27682.1 - 1.4e-21 77.8 12.0 2e-21 77.3 12.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 VAD1-2 PF15310.6 VBB27682.1 - 0.065 13.1 6.1 0.098 12.5 6.1 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Asparaginase_2 PF01112.18 VBB27682.1 - 0.098 11.7 0.2 10 5.0 0.4 2.0 2 0 0 2 2 2 0 Asparaginase Helicase_C PF00271.31 VBB27684.1 - 2e-21 76.4 0.0 2.7e-19 69.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB27684.1 - 1.6e-17 63.9 0.3 4.6e-17 62.3 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 VBB27684.1 - 1.9e-14 54.1 1.9 4.5e-14 52.9 0.5 2.5 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 VBB27684.1 - 1.2e-13 50.8 0.2 4.4e-13 49.0 0.2 2.0 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 VBB27684.1 - 4.8e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 VBB27684.1 - 2e-06 27.9 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GhoS PF11080.8 VBB27684.1 - 0.15 12.1 0.2 6.5 6.8 0.0 3.1 3 0 0 3 3 3 0 Endoribonuclease GhoS Pkinase PF00069.25 VBB27685.1 - 2.3e-59 200.9 0.0 2.3e-59 200.9 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27685.1 - 3.4e-28 98.6 0.0 3.4e-28 98.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 VBB27685.1 - 1.2e-13 51.3 7.2 0.012 16.5 0.0 7.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Rho_Binding PF08912.11 VBB27685.1 - 1.4e-06 29.0 8.1 1.4e-06 29.0 8.1 9.5 5 4 5 10 10 10 1 Rho Binding C1_1 PF00130.22 VBB27685.1 - 0.00059 19.7 0.5 0.0016 18.3 0.5 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 VBB27685.1 - 0.005 17.3 0.0 0.23 12.0 0.0 2.8 1 1 0 1 1 1 1 PH domain Ge1_WD40 PF16529.5 VBB27685.1 - 0.016 14.2 0.2 0.07 12.1 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase_C PF00433.24 VBB27685.1 - 0.07 13.8 1.1 0.22 12.3 1.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain OrfB_Zn_ribbon PF07282.11 VBB27685.1 - 0.088 12.7 0.1 0.32 11.0 0.1 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Rap_GAP PF02145.15 VBB27687.1 - 1.4e-28 99.7 0.0 6e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Cir_N PF10197.9 VBB27688.1 - 4.4e-06 26.8 12.1 4.4e-06 26.8 12.1 4.3 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR HEAT PF02985.22 VBB27689.1 - 8.3e-05 22.5 8.1 6 7.4 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 VBB27689.1 - 0.012 15.9 0.2 17 5.9 0.0 4.0 5 0 0 5 5 5 0 HEAT repeats YozD PF14162.6 VBB27689.1 - 0.3 11.4 1.2 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 YozD-like protein HEAT_EZ PF13513.6 VBB27689.1 - 5.1 7.7 11.3 2.5 8.7 0.2 5.5 7 1 0 7 7 7 0 HEAT-like repeat MH2 PF03166.14 VBB27690.1 - 5e-13 49.7 0.3 8.4e-13 49.0 0.3 1.5 1 1 0 1 1 1 1 MH2 domain ODV-E18 PF10717.9 VBB27692.1 - 0.22 11.4 3.9 0.11 12.4 0.9 1.9 1 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 NOA36 PF06524.12 VBB27692.1 - 0.24 10.7 10.3 1.1 8.5 1.0 2.1 2 0 0 2 2 2 0 NOA36 protein Orf78 PF06024.12 VBB27692.1 - 0.3 11.4 0.1 0.3 11.4 0.1 2.1 2 0 0 2 2 2 0 Orf78 (ac78) RICTOR_M PF14666.6 VBB27693.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain UPF0220 PF05255.11 VBB27694.1 - 1.5e-37 128.7 6.9 1.8e-37 128.4 6.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ABC_membrane PF00664.23 VBB27695.1 - 9.1e-35 120.6 12.2 1.2e-34 120.2 12.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 VBB27695.1 - 1.8e-33 115.9 0.0 6e-33 114.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 VBB27695.1 - 3.6e-06 26.6 0.1 0.00026 20.5 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 VBB27695.1 - 0.0027 17.5 0.7 0.0051 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 VBB27695.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 VBB27695.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 VBB27695.1 - 0.029 14.7 0.0 0.075 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 VBB27695.1 - 0.052 13.3 0.2 0.46 10.2 0.0 2.4 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 VBB27695.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 VBB27695.1 - 0.11 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain PRK PF00485.18 VBB27695.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 VBB27695.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AXIN1_TNKS_BD PF16646.5 VBB27696.1 - 1.4 9.9 4.2 40 5.2 0.3 2.8 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain DWNN PF08783.11 VBB27697.1 - 9.6e-24 83.5 0.3 3e-23 81.9 0.3 2.0 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 VBB27697.1 - 6.6e-09 35.4 5.0 1.3e-08 34.5 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 VBB27697.1 - 7.7e-08 32.1 6.8 1.9e-07 30.8 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB27697.1 - 0.00011 22.2 7.7 0.00028 20.8 7.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 VBB27697.1 - 0.00062 20.1 8.1 0.0014 18.9 8.1 1.6 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.15 VBB27697.1 - 0.0012 19.0 0.0 0.0046 17.1 0.0 2.1 1 0 0 1 1 1 1 U-box domain zf-C3HC4 PF00097.25 VBB27697.1 - 0.0012 18.6 4.9 0.0012 18.6 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB27697.1 - 0.002 18.0 8.5 0.002 18.0 8.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCHC PF00098.23 VBB27697.1 - 0.052 13.6 2.1 0.12 12.5 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_4 PF15227.6 VBB27697.1 - 0.067 13.4 9.2 0.14 12.3 9.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 VBB27697.1 - 0.15 11.9 5.2 0.32 10.8 5.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 VBB27697.1 - 0.16 11.8 13.6 0.025 14.5 7.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ldl_recept_a PF00057.18 VBB27698.1 - 0.00028 21.0 5.5 0.00048 20.3 5.5 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PBP1_TM PF14812.6 VBB27698.1 - 0.039 14.3 0.4 0.067 13.6 0.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prominin PF05478.11 VBB27699.1 - 5.7e-10 37.8 16.1 4.7e-09 34.8 8.9 2.6 1 1 1 2 2 2 2 Prominin NnrS PF05940.12 VBB27699.1 - 0.00067 19.1 2.0 0.001 18.5 2.0 1.2 1 0 0 1 1 1 1 NnrS protein ORF11CD3 PF10549.9 VBB27699.1 - 0.39 10.9 2.4 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 ORF11CD3 domain RIC1 PF07064.13 VBB27700.1 - 9.7e-78 261.0 0.5 2.4e-77 259.8 0.5 1.7 1 0 0 1 1 1 1 RIC1 His_Phos_2 PF00328.22 VBB27701.1 - 4.8e-29 101.9 0.1 7.9e-24 84.7 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF4138 PF13595.6 VBB27701.1 - 0.057 12.7 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF4833 PF16117.5 VBB27701.1 - 0.12 12.4 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4833) Peptidase_C48 PF02902.19 VBB27702.1 - 1e-25 90.9 0.0 2.3e-25 89.7 0.0 1.5 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MIG-14_Wnt-bd PF06664.12 VBB27703.1 - 3.1e-79 266.2 20.1 3.1e-79 266.2 20.1 2.0 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion PrgI PF12666.7 VBB27703.1 - 0.86 10.4 0.0 0.86 10.4 0.0 3.3 3 1 0 3 3 3 0 PrgI family protein zf-C2H2 PF00096.26 VBB27704.1 - 0.0012 19.2 0.0 0.0012 19.2 0.0 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 VBB27704.1 - 0.002 18.1 0.0 0.0065 16.5 0.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf_ZIC PF18366.1 VBB27704.1 - 0.0032 17.5 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 VBB27704.1 - 0.044 14.6 0.0 0.044 14.6 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Sec23_trunk PF04811.15 VBB27706.1 - 3.5e-53 180.7 0.1 8.7e-52 176.1 0.1 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 VBB27706.1 - 4e-19 68.4 0.3 1.4e-18 66.6 0.2 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 VBB27706.1 - 1.2e-18 67.6 0.0 3.1e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 VBB27706.1 - 2.8e-12 46.5 6.9 9.4e-12 44.8 6.9 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 VBB27706.1 - 2.2e-06 27.4 0.0 9.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 VBB27706.1 - 0.06 12.7 0.2 0.17 11.3 0.2 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Exo_endo_phos PF03372.23 VBB27707.1 - 3.9e-19 69.1 0.0 1.6e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 VBB27707.1 - 2e-08 33.8 4.3 5.6e-08 32.4 3.8 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 VBB27707.1 - 1.7e-07 31.5 4.9 0.0012 19.1 0.6 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB27707.1 - 0.0088 16.4 5.4 6.5 7.7 0.1 4.0 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 VBB27707.1 - 0.055 13.5 3.1 9 6.6 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Condensin2nSMC PF12422.8 VBB27708.1 - 1.5e-21 77.1 1.1 1.5e-21 77.1 1.1 2.6 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 VBB27708.1 - 0.001 19.2 0.3 11 6.5 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat CLASP_N PF12348.8 VBB27708.1 - 0.023 14.3 0.0 0.23 11.0 0.0 2.4 2 1 1 3 3 3 0 CLASP N terminal MBOAT PF03062.19 VBB27709.1 - 4.2e-43 148.0 16.5 9.2e-43 146.9 16.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MgtC PF02308.16 VBB27709.1 - 0.27 11.6 2.1 17 5.8 0.5 3.0 2 1 0 2 2 2 0 MgtC family DUF2842 PF11003.8 VBB27709.1 - 6.5 7.1 11.3 0.078 13.2 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) LURAP PF14854.6 VBB27712.1 - 0.014 15.4 3.1 0.014 15.4 3.1 2.5 2 1 0 2 2 2 0 Leucine rich adaptor protein UPF0449 PF15136.6 VBB27712.1 - 0.07 13.6 4.7 1.9 9.0 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HEAT PF02985.22 VBB27713.1 - 5e-12 45.0 2.9 0.088 13.1 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat CLASP_N PF12348.8 VBB27713.1 - 1.5e-07 31.3 0.0 0.0026 17.3 0.0 2.8 2 2 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 VBB27713.1 - 8.2e-06 25.9 7.0 2.3 8.2 0.3 5.2 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 VBB27713.1 - 0.00042 20.8 0.2 3 8.4 0.0 4.4 4 1 0 4 4 4 1 HEAT-like repeat TAN PF11640.8 VBB27713.1 - 0.012 15.7 1.3 1.3 9.2 0.2 3.2 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair PDDEXK_6 PF04720.12 VBB27713.1 - 0.015 15.2 0.1 0.042 13.8 0.1 1.7 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Zip PF02535.22 VBB27715.1 - 2.1e-40 139.0 0.0 3.3e-40 138.3 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Neur_chan_LBD PF02931.23 VBB27718.1 - 1.8e-27 96.2 1.6 3.8e-27 95.1 1.6 1.6 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB27718.1 - 8.4e-14 52.2 7.7 5.9e-12 46.2 0.6 2.7 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.21 VBB27718.1 - 0.0015 17.9 0.0 0.022 14.1 0.1 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) MetOD2 PF18548.1 VBB27718.1 - 0.089 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 Orf78 PF06024.12 VBB27718.1 - 0.23 11.8 4.5 0.85 10.0 0.2 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Ank_2 PF12796.7 VBB27719.1 - 2.9e-31 107.9 3.6 3.5e-11 43.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB27719.1 - 1.5e-26 92.4 3.8 2.2e-08 34.4 0.2 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB27719.1 - 1.4e-25 89.0 8.3 4.8e-06 26.7 0.3 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 VBB27719.1 - 4.1e-23 80.8 13.4 0.00012 22.3 0.1 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 VBB27719.1 - 5.3e-19 66.3 7.4 0.017 15.6 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat SAM_1 PF00536.30 VBB27719.1 - 3.1e-12 46.7 0.2 1e-11 45.1 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PID PF00640.23 VBB27719.1 - 3.6e-12 46.5 1.1 1.6e-11 44.4 1.1 2.2 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SAM_2 PF07647.17 VBB27719.1 - 5.5e-09 36.0 0.0 2.1e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) 7tm_1 PF00001.21 VBB27720.1 - 0.065 12.6 0.8 0.078 12.3 0.8 1.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TMEM132D_C PF15706.5 VBB27720.1 - 0.069 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEMspv1-c74-12 PF11044.8 VBB27721.1 - 0.35 10.9 2.8 3 7.9 0.5 2.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Glyco_transf_8 PF01501.20 VBB27722.1 - 1.8e-16 60.5 0.7 1.2e-14 54.5 0.7 2.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 VBB27722.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 VBB27722.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase EGF_2 PF07974.13 VBB27725.1 - 0.0022 18.3 3.7 0.0022 18.3 3.7 3.4 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.24 VBB27725.1 - 0.0024 18.0 17.2 0.065 13.4 1.9 3.2 1 1 2 3 3 3 2 Laminin EGF domain CHCH PF06747.13 VBB27726.1 - 4.7e-07 29.8 2.2 1.1e-06 28.6 2.2 1.6 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.9 VBB27726.1 - 0.039 14.2 1.2 0.071 13.4 1.2 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Homeodomain PF00046.29 VBB27727.1 - 2.1e-21 75.5 2.0 3.8e-21 74.7 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27727.1 - 0.0037 17.1 0.1 0.0094 15.8 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Med24_N PF11277.8 VBB27728.1 - 2.2e-51 175.0 17.8 4.7e-42 144.2 5.1 3.0 2 1 1 3 3 3 3 Mediator complex subunit 24 N-terminal Trypsin PF00089.26 VBB27729.1 - 2.2e-26 93.1 0.2 1.1e-25 90.8 0.2 1.9 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 VBB27729.1 - 3.7e-08 33.3 0.1 1.1e-07 31.7 0.1 1.7 1 1 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 VBB27729.1 - 1.1e-05 26.4 0.0 1.5e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 VBB27729.1 - 0.056 13.8 0.3 0.16 12.4 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1986) Pkinase PF00069.25 VBB27731.1 - 9.3e-70 235.0 0.0 1.2e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27731.1 - 1.5e-36 126.1 0.0 2.4e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB27731.1 - 0.00059 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 VBB27731.1 - 0.0096 14.9 1.9 0.02 13.9 1.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 VBB27731.1 - 0.013 14.8 0.0 0.037 13.3 0.0 1.7 1 1 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 VBB27731.1 - 0.027 14.1 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 VBB27731.1 - 0.096 12.0 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BAH PF01426.18 VBB27732.1 - 7e-29 100.2 0.0 7e-28 96.9 0.0 2.3 1 1 0 1 1 1 1 BAH domain MTA_R1 PF17226.2 VBB27732.1 - 6.1e-21 74.4 2.7 2e-20 72.7 2.7 2.0 1 0 0 1 1 1 1 MTA R1 domain ELM2 PF01448.24 VBB27732.1 - 1.5e-13 51.3 0.1 1.5e-13 51.3 0.1 2.5 3 0 0 3 3 3 1 ELM2 domain Myb_DNA-binding PF00249.31 VBB27732.1 - 1.2e-07 31.8 0.1 2.4e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain GATA PF00320.27 VBB27732.1 - 0.00015 21.3 3.2 0.00033 20.2 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-bind_7 PF15963.5 VBB27732.1 - 0.024 14.5 0.4 0.063 13.2 0.4 1.7 1 0 0 1 1 1 0 Myb DNA-binding like 7TM_GPCR_Srx PF10328.9 VBB27733.1 - 0.0015 18.2 10.8 0.0018 17.9 10.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 VBB27733.1 - 0.074 12.4 7.2 0.1 11.9 7.1 1.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DRY_EERY PF09750.9 VBB27734.1 - 2.4e-36 125.0 0.2 2.4e-36 125.0 0.2 5.1 6 1 0 6 6 6 1 Alternative splicing regulator Mit_KHE1 PF10173.9 VBB27734.1 - 1.9 8.5 6.0 0.32 11.1 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related RNase_Zc3h12a PF11977.8 VBB27735.1 - 1.6e-13 50.7 0.5 3.1e-10 40.0 0.0 2.4 1 1 1 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain DUF1011 PF06237.12 VBB27736.1 - 1.9e-08 34.5 0.7 1.9e-08 34.5 0.7 4.8 3 2 0 5 5 5 2 Protein of unknown function (DUF1011) DUF1774 PF08611.10 VBB27736.1 - 4.7 7.6 11.1 0.06 13.7 2.4 2.3 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) ATP-synt_E PF05680.12 VBB27737.1 - 6.6e-09 36.0 1.2 0.00031 21.0 0.1 2.2 2 0 0 2 2 2 2 ATP synthase E chain Tyrosinase PF00264.20 VBB27738.1 - 2e-28 100.2 0.7 1.3e-26 94.3 0.7 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase ShK PF01549.24 VBB27738.1 - 4.2e-06 27.2 9.3 4.2e-06 27.2 9.3 3.7 3 1 1 4 4 4 2 ShK domain-like DUF1075 PF06388.11 VBB27740.1 - 0.00094 19.2 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Pkinase PF00069.25 VBB27741.1 - 2.1e-39 135.5 0.0 5.1e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27741.1 - 1.1e-21 77.3 0.0 2.2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.10 VBB27741.1 - 0.034 14.2 2.9 0.095 12.8 1.7 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF1664 PF07889.12 VBB27741.1 - 1.4 9.0 6.5 2.4 8.2 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S24 PF00717.23 VBB27742.1 - 3.4e-07 30.1 0.5 1.4e-05 24.9 0.2 2.8 2 1 0 2 2 2 1 Peptidase S24-like HIGH_NTase1 PF05636.11 VBB27743.1 - 0.016 14.5 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase SirA PF10747.9 VBB27743.1 - 0.036 14.4 0.3 2.7 8.3 0.3 2.4 2 1 0 2 2 2 0 Sporulation inhibitor of replication protein SirA zf-C2H2 PF00096.26 VBB27745.1 - 1.6e-25 88.1 46.4 5.8e-06 26.5 2.2 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB27745.1 - 2.3e-24 84.7 34.9 9.7e-07 28.9 0.1 7.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB27745.1 - 4.6e-19 67.5 43.2 0.0011 19.6 1.6 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB27745.1 - 3.6e-13 49.4 28.8 0.0032 17.7 0.2 6.8 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB27745.1 - 2.6e-06 27.3 36.3 0.15 12.1 0.7 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 VBB27745.1 - 3.3e-06 27.3 33.6 0.23 11.9 0.4 6.7 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 VBB27745.1 - 5.9e-06 26.5 19.9 0.00017 21.8 0.5 4.4 3 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 VBB27745.1 - 0.00016 21.4 5.7 0.033 14.0 0.5 3.4 2 1 1 3 3 3 1 GAGA factor zf-C2H2_8 PF15909.5 VBB27745.1 - 0.042 14.2 19.0 0.29 11.4 5.7 3.2 3 1 0 3 3 3 0 C2H2-type zinc ribbon Zn-C2H2_12 PF18112.1 VBB27745.1 - 0.078 13.5 14.2 0.83 10.2 1.1 4.9 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain PyrI_C PF02748.15 VBB27745.1 - 0.12 12.3 0.3 0.12 12.3 0.3 4.9 5 1 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PHD_4 PF16866.5 VBB27745.1 - 0.46 10.6 10.6 2 8.6 1.0 3.8 2 1 0 3 3 3 0 PHD-finger zinc_ribbon_15 PF17032.5 VBB27745.1 - 0.92 10.3 14.8 8.5 7.2 0.5 3.8 3 1 1 4 4 4 0 zinc-ribbon family zf-RING_11 PF17123.5 VBB27745.1 - 1.1 9.0 8.1 1.3 8.8 0.1 4.0 4 0 0 4 4 4 0 RING-like zinc finger DUF3268 PF11672.8 VBB27745.1 - 1.9 8.8 14.5 0.45 10.9 2.0 3.2 2 1 2 4 4 4 0 zinc-finger-containing domain C1_4 PF07975.12 VBB27745.1 - 7.1 7.0 24.3 4.3 7.7 0.8 4.9 1 1 4 5 5 5 0 TFIIH C1-like domain Cpn60_TCP1 PF00118.24 VBB27747.1 - 1.9e-152 508.3 8.2 2.2e-152 508.2 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Surp PF01805.20 VBB27748.1 - 9.9e-13 47.9 0.4 3.8e-12 46.0 0.4 2.0 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 VBB27748.1 - 2.2e-11 44.4 1.4 6.6e-11 42.9 0.3 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. G-patch PF01585.23 VBB27748.1 - 1.7e-08 34.2 1.1 3e-08 33.4 1.1 1.5 1 0 0 1 1 1 1 G-patch domain DUF2681 PF10883.8 VBB27748.1 - 0.009 16.4 1.1 0.009 16.4 1.1 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2681) Apt1 PF10351.9 VBB27748.1 - 0.022 13.6 16.1 0.04 12.8 16.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain VPS53_C PF16854.5 VBB27748.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Macoilin PF09726.9 VBB27748.1 - 1.4 7.4 17.0 2.4 6.6 17.0 1.3 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 VBB27748.1 - 2.3 5.2 7.5 3.5 4.6 7.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dsh_C PF12316.8 VBB27748.1 - 4.6 7.6 31.7 6.1 7.2 23.6 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 VBB27748.1 - 5 5.3 18.0 8 4.6 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Guanylate_cyc PF00211.20 VBB27749.1 - 1.8e-54 184.1 0.1 4.2e-54 183.0 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 VBB27749.1 - 1.7e-25 89.8 0.0 3.3e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB27749.1 - 3.9e-17 62.5 0.1 9.3e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 VBB27749.1 - 2.6e-09 36.7 0.5 4.6e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 VBB27749.1 - 0.0038 16.7 0.2 0.0068 15.9 0.2 1.4 1 0 0 1 1 1 1 Heme NO binding associated Globin PF00042.22 VBB27750.1 - 0.014 15.9 0.0 0.034 14.7 0.0 1.7 1 1 0 1 1 1 0 Globin D5_N PF08706.11 VBB27750.1 - 0.056 13.7 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 D5 N terminal like CH_2 PF06294.11 VBB27750.1 - 0.057 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 CH-like domain in sperm protein adh_short PF00106.25 VBB27751.1 - 2.6e-34 118.4 0.1 5e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB27751.1 - 1.6e-26 93.3 0.0 3.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB27751.1 - 2.7e-06 27.4 0.1 7.6e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 VBB27753.1 - 1.4e-15 57.4 0.0 2.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 VBB27753.1 - 1.8e-08 34.2 0.0 7.2e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 VBB27753.1 - 1e-05 26.6 0.0 2.7e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAM92 PF06730.11 VBB27753.1 - 0.053 12.9 0.1 0.096 12.1 0.1 1.3 1 0 0 1 1 1 0 FAM92 protein CoA_binding_2 PF13380.6 VBB27753.1 - 0.086 13.3 0.0 2 9.0 0.0 2.4 1 1 1 2 2 2 0 CoA binding domain DNA_photolyase PF00875.18 VBB27753.1 - 0.13 12.2 0.2 3.9 7.4 0.0 2.2 1 1 1 2 2 2 0 DNA photolyase CAAD PF14159.6 VBB27753.1 - 0.18 11.6 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase zf-BED PF02892.15 VBB27754.1 - 0.00011 22.1 0.1 0.00031 20.7 0.1 1.9 1 0 0 1 1 1 1 BED zinc finger OGG_N PF07934.12 VBB27755.1 - 9.7e-16 58.0 0.0 2e-14 53.7 0.0 2.4 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 VBB27755.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.7 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HMG_box PF00505.19 VBB27757.1 - 3.1e-13 49.9 0.9 5.7e-13 49.1 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB27757.1 - 1.6e-10 41.4 3.3 3e-10 40.5 3.3 1.3 1 0 0 1 1 1 1 HMG-box domain zf-C2H2_aberr PF17017.5 VBB27757.1 - 1.5e-05 25.3 1.2 1.5e-05 25.3 1.2 1.5 2 0 0 2 2 2 1 Aberrant zinc-finger DUF1059 PF06348.11 VBB27757.1 - 0.097 12.9 0.3 14 6.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1059) FOXP-CC PF16159.5 VBB27757.1 - 0.13 12.9 3.2 0.19 12.4 0.7 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 VBB27757.1 - 0.22 12.0 3.8 5.6 7.6 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 VBB27757.1 - 1.2 8.9 4.6 2.3 8.1 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DcpS_C PF11969.8 VBB27758.1 - 9e-30 103.5 0.4 1.9e-29 102.4 0.4 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TFIIS_C PF01096.18 VBB27758.1 - 1.3e-18 66.5 3.2 1.3e-18 66.5 3.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DcpS PF05652.12 VBB27758.1 - 7.5e-18 65.3 0.0 1.5e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal RNA_POL_M_15KD PF02150.16 VBB27758.1 - 1.2e-06 28.2 3.4 2.9e-06 27.0 3.4 1.7 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.12 VBB27758.1 - 0.013 15.4 0.1 5.7 7.0 0.0 2.8 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 VBB27758.1 - 0.035 14.1 10.4 0.073 13.1 1.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain YhfH PF14149.6 VBB27758.1 - 0.17 11.9 6.5 0.5 10.4 6.5 1.8 1 0 0 1 1 1 0 YhfH-like protein Lar_restr_allev PF14354.6 VBB27758.1 - 0.58 10.6 6.6 0.59 10.5 1.1 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 VBB27758.1 - 0.75 10.0 7.2 18 5.6 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 VBB27758.1 - 1.2 9.2 7.6 0.13 12.3 2.0 2.0 2 0 0 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.12 VBB27758.1 - 1.5 8.4 7.9 1.2 8.7 4.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_ligase_ZBD PF03119.16 VBB27758.1 - 2 8.5 9.0 0.69 10.0 0.7 3.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 VBB27758.1 - 3.8 7.6 9.4 37 4.5 9.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C4_Topoisom PF01396.19 VBB27758.1 - 4.6 7.1 9.4 2.6 7.9 4.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.12 VBB27758.1 - 6.5 6.8 11.8 1.3 9.1 2.6 2.8 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger HSP70 PF00012.20 VBB27759.1 - 9.6e-213 707.7 19.0 6.4e-206 685.1 10.2 3.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 VBB27759.1 - 6.2e-10 38.4 0.2 2.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 VBB27759.1 - 0.00017 21.9 0.1 0.84 10.1 0.0 3.0 2 1 0 2 2 2 2 Cell division protein FtsA MCLC PF05934.11 VBB27759.1 - 0.0021 16.9 0.5 0.0033 16.2 0.2 1.4 2 0 0 2 2 2 1 Mid-1-related chloride channel (MCLC) DDR PF08841.10 VBB27759.1 - 0.052 12.5 0.1 0.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 VBB27759.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 VBB27759.1 - 0.15 11.3 1.4 1.6 7.9 0.2 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase betaPIX_CC PF16523.5 VBB27759.1 - 5.3 6.9 7.5 0.78 9.6 0.6 2.7 3 0 0 3 3 3 0 betaPIX coiled coil Proteasome PF00227.26 VBB27760.1 - 2.1e-46 157.8 0.0 2.5e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 VBB27760.1 - 2.4e-12 46.3 0.1 6e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ATP_synt_H PF05493.13 VBB27761.1 - 6.8e-26 90.5 7.3 9.2e-26 90.1 7.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Xin PF08043.12 VBB27761.1 - 7.9 6.3 6.8 45 3.9 3.1 2.5 2 0 0 2 2 2 0 Xin repeat Pkinase PF00069.25 VBB27762.1 - 1.4e-20 73.8 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27762.1 - 1.9e-12 47.0 0.1 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Laminin_II PF06009.12 VBB27763.1 - 0.01 15.8 3.2 0.01 15.8 3.2 2.2 2 0 0 2 2 2 0 Laminin Domain II Pox_A_type_inc PF04508.12 VBB27763.1 - 0.29 11.0 0.1 0.29 11.0 0.1 4.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CC2-LZ PF16516.5 VBB27763.1 - 0.58 10.6 12.5 0.51 10.7 2.7 2.9 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 VBB27763.1 - 2.1 8.4 6.9 0.86 9.7 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Striatin PF08232.12 VBB27763.1 - 5.5 7.6 14.1 0.44 11.1 1.5 3.0 1 1 1 2 2 2 0 Striatin family Dynamin_M PF01031.20 VBB27764.1 - 6.9e-100 333.9 0.0 1.6e-99 332.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 VBB27764.1 - 4.3e-51 173.3 0.0 1.1e-50 172.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 VBB27764.1 - 4.1e-30 103.8 4.8 1.2e-29 102.3 4.8 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 VBB27764.1 - 0.0013 18.7 0.3 0.037 14.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 VBB27764.1 - 0.17 12.3 0.0 6.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DCP1 PF06058.13 VBB27765.1 - 1.6e-35 121.5 0.0 2.6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 VBB27765.1 - 1.8e-06 27.1 0.1 4.2e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus TIM21 PF08294.11 VBB27766.1 - 2.1e-24 86.1 0.0 2.8e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 VBB27766.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RSN1_TM PF13967.6 VBB27766.1 - 0.036 13.8 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport CD34_antigen PF06365.12 VBB27766.1 - 0.047 13.3 0.2 0.066 12.8 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family HECT PF00632.25 VBB27767.1 - 3.8e-90 302.5 2.3 6.4e-90 301.7 2.3 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 VBB27767.1 - 1.1e-74 251.7 2.2 1.1e-56 192.5 0.2 4.4 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) UBM PF14377.6 VBB27767.1 - 9.5e-23 78.9 15.1 1.2e-09 37.3 0.6 3.8 3 0 0 3 3 3 3 Ubiquitin binding region DUF908 PF06012.12 VBB27767.1 - 5e-18 65.7 21.3 1.7e-10 40.9 2.3 3.2 3 0 0 3 3 3 2 Domain of Unknown Function (DUF908) WWE PF02825.20 VBB27767.1 - 5.1e-09 36.6 0.0 2.6e-08 34.3 0.0 2.4 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 VBB27767.1 - 5.3e-05 23.0 0.2 0.00033 20.5 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Arm_2 PF04826.13 VBB27767.1 - 0.52 9.7 3.8 0.24 10.8 0.7 2.0 2 0 0 2 2 2 0 Armadillo-like ECSIT PF06239.11 VBB27768.1 - 2.6e-62 209.9 1.3 4.4e-62 209.1 1.3 1.2 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 VBB27768.1 - 9.8e-32 110.1 0.4 2e-31 109.0 0.2 1.7 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein GRAM PF02893.20 VBB27769.1 - 3.3e-09 36.6 0.0 7.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 VBB27769.1 - 0.0004 20.5 0.0 0.00091 19.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-C3HC4_3 PF13920.6 VBB27770.1 - 5.4e-09 35.8 7.3 5.4e-09 35.8 7.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB27770.1 - 3.1e-07 30.6 10.8 8.9e-07 29.2 10.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB27770.1 - 4.4e-07 29.6 11.6 5.9e-07 29.2 10.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB27770.1 - 1.1e-06 28.4 9.2 2.5e-06 27.2 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB27770.1 - 1.8e-05 24.5 6.5 4e-05 23.4 6.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 VBB27770.1 - 0.00025 21.0 3.0 0.00025 21.0 3.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 VBB27770.1 - 0.0019 18.4 9.2 0.0044 17.3 9.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 VBB27770.1 - 0.003 17.5 9.1 0.018 15.0 7.9 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 VBB27770.1 - 0.11 12.3 7.7 0.36 10.7 7.7 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain F_actin_bind PF08919.10 VBB27770.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 F-actin binding zf-C3HC4_4 PF15227.6 VBB27770.1 - 0.33 11.1 10.0 0.82 9.9 10.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MgtE PF01769.16 VBB27771.1 - 6.2e-41 139.7 26.7 7.7e-23 81.2 4.2 3.4 2 1 1 3 3 3 2 Divalent cation transporter Aminotran_1_2 PF00155.21 VBB27772.1 - 2.2e-68 231.1 0.0 2.6e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 VBB27772.1 - 0.00032 19.4 0.0 0.00048 18.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 VBB27772.1 - 0.0017 17.3 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 VBB27772.1 - 0.0032 16.8 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 VBB27772.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pro_dh PF01619.18 VBB27773.1 - 1.2e-72 245.0 5.2 4.9e-72 243.0 5.2 2.1 1 1 0 1 1 1 1 Proline dehydrogenase DUF424 PF04242.13 VBB27773.1 - 0.0021 18.3 0.1 0.0069 16.6 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF424) PPR_3 PF13812.6 VBB27773.1 - 0.0026 17.8 0.8 0.021 14.9 0.0 2.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain EF-hand_1 PF00036.32 VBB27773.1 - 0.093 12.3 0.5 0.9 9.2 0.0 2.8 2 0 0 2 2 2 0 EF hand DUF4145 PF13643.6 VBB27773.1 - 0.18 12.0 1.2 0.93 9.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) EF-hand_7 PF13499.6 VBB27773.1 - 0.19 12.2 1.5 0.36 11.3 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.25 VBB27774.1 - 7.3e-57 192.7 0.0 8.7e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27774.1 - 3.2e-41 141.3 0.0 4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB27774.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB27774.1 - 0.002 17.1 0.2 0.011 14.7 0.2 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB27774.1 - 0.002 16.9 0.2 0.0058 15.5 0.0 1.4 1 1 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB27774.1 - 0.003 16.7 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 VBB27774.1 - 0.073 12.0 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 VBB27774.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_membrane_2 PF06472.15 VBB27775.1 - 1.7e-81 273.6 8.4 2.5e-81 273.0 8.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 VBB27775.1 - 1.7e-17 64.2 0.0 3.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 VBB27775.1 - 0.00026 20.9 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 VBB27775.1 - 0.0056 16.1 0.2 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 VBB27775.1 - 0.0057 17.2 0.3 0.014 15.9 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 VBB27775.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-RING_2 PF13639.6 VBB27776.1 - 1.4e-12 47.8 7.5 1.4e-12 47.8 7.5 2.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB27776.1 - 6e-08 32.4 6.8 6e-08 32.4 6.8 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB27776.1 - 6.6e-08 32.7 3.3 6.6e-08 32.7 3.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 VBB27776.1 - 7.3e-08 32.0 1.8 2e-07 30.6 1.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 VBB27776.1 - 2.6e-06 27.2 5.2 2.6e-06 27.2 5.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB27776.1 - 4.3e-06 26.6 3.4 4.3e-06 26.6 3.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB27776.1 - 0.00012 22.0 5.9 0.00012 22.0 5.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 VBB27776.1 - 0.00024 21.1 2.0 0.00024 21.1 2.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 VBB27776.1 - 0.00031 20.5 3.4 0.00031 20.5 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CrgA PF06781.12 VBB27776.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA PspB PF06667.12 VBB27776.1 - 0.015 15.4 0.4 0.035 14.2 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B Prok-RING_4 PF14447.6 VBB27776.1 - 0.018 14.9 8.6 0.018 14.9 8.6 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 VBB27776.1 - 0.4 10.3 7.7 0.039 13.6 2.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 VBB27776.1 - 8.4 6.4 10.4 0.71 9.8 3.7 2.6 2 0 0 2 2 2 0 PHD-finger F-box PF00646.33 VBB27777.1 - 0.00022 21.0 0.2 0.007 16.2 0.0 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 VBB27777.1 - 0.0082 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 VBB27777.1 - 0.029 14.7 4.0 0.12 12.7 0.0 3.0 3 1 1 4 4 4 0 PRANC domain F-box_4 PF15966.5 VBB27777.1 - 0.032 14.1 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 F-box SlyX PF04102.12 VBB27777.1 - 0.37 11.4 2.4 1 10.1 0.1 2.5 2 1 0 2 2 2 0 SlyX YkyA PF10368.9 VBB27777.1 - 1.2 8.8 5.4 11 5.7 0.1 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein GLTP PF08718.11 VBB27778.1 - 2.7e-40 138.1 0.0 3.2e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) FSIP2 PF15783.5 VBB27778.1 - 0.037 12.0 0.0 0.049 11.6 0.0 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 CUE PF02845.16 VBB27778.1 - 0.094 12.4 0.6 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 CUE domain HTH_5 PF01022.20 VBB27778.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family ATP-synt_C PF00137.21 VBB27779.1 - 3.7e-09 36.8 11.0 5.3e-09 36.3 11.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit C AMP-binding PF00501.28 VBB27780.1 - 1.1e-10 40.8 0.0 9.1e-08 31.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding PF00501.28 VBB27781.1 - 2.3e-86 290.0 0.0 3.2e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB27781.1 - 3.1e-21 76.1 0.3 7.5e-21 74.9 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 VBB27781.1 - 3.6e-07 30.0 0.5 8.6e-07 28.8 0.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus RhoGAP-FF1 PF16512.5 VBB27781.1 - 0.013 16.2 0.5 0.035 14.8 0.5 1.7 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain DMRL_synthase PF00885.19 VBB27781.1 - 0.041 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase BRCT_2 PF16589.5 VBB27782.1 - 3e-07 30.8 0.2 0.0029 18.0 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 VBB27782.1 - 6.4e-05 23.2 1.4 0.08 13.3 0.2 3.2 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 VBB27782.1 - 0.00018 21.3 8.4 0.00053 19.8 8.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB27782.1 - 0.00035 20.5 8.5 0.0011 19.0 8.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB27782.1 - 0.00044 20.1 10.8 0.0012 18.7 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RTT107_BRCT_5 PF16770.5 VBB27782.1 - 0.0081 16.0 0.0 0.14 12.0 0.1 2.8 2 1 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_5 PF14634.6 VBB27782.1 - 0.0088 16.0 10.4 0.035 14.1 10.4 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 VBB27782.1 - 0.0091 15.8 4.5 0.0091 15.8 4.5 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 VBB27782.1 - 0.026 14.7 10.2 0.096 12.9 10.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 VBB27782.1 - 0.03 14.7 8.7 0.1 13.0 8.7 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 VBB27782.1 - 0.11 12.4 10.5 0.31 10.9 10.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 VBB27782.1 - 0.38 10.9 10.4 0.45 10.7 8.4 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 TGF_beta PF00019.20 VBB27783.1 - 6.6e-23 81.7 2.6 9.9e-23 81.1 2.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain Filament PF00038.21 VBB27784.1 - 2.6e-70 237.5 52.1 2.4e-68 231.1 52.1 2.3 1 1 0 1 1 1 1 Intermediate filament protein DUF2353 PF09789.9 VBB27784.1 - 3.9e-05 23.2 13.9 3.9e-05 23.2 13.9 3.2 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) APG6_N PF17675.1 VBB27784.1 - 5e-05 23.8 53.1 0.35 11.4 18.7 5.5 1 1 5 6 6 6 3 Apg6 coiled-coil region Myosin_tail_1 PF01576.19 VBB27784.1 - 5.2e-05 21.3 50.2 0.0027 15.6 21.5 2.7 1 1 1 2 2 2 2 Myosin tail Spc7 PF08317.11 VBB27784.1 - 6.9e-05 21.9 40.6 0.00081 18.4 10.6 3.0 2 1 1 3 3 3 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 VBB27784.1 - 9.1e-05 22.5 40.8 0.013 15.6 14.0 5.1 1 1 3 5 5 4 3 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 VBB27784.1 - 0.00018 21.8 9.5 0.00018 21.8 9.5 4.0 1 1 4 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 VBB27784.1 - 0.00039 20.8 39.0 0.00039 20.8 6.1 5.5 1 1 5 6 6 6 1 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 VBB27784.1 - 0.0012 18.8 48.0 0.02 14.9 19.5 4.0 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 VBB27784.1 - 0.0023 18.6 35.8 0.11 13.2 8.0 5.7 1 1 4 5 5 5 1 Initiation control protein YabA SOGA PF11365.8 VBB27784.1 - 0.0073 17.4 32.7 0.014 16.5 4.8 5.4 1 1 5 6 6 6 2 Protein SOGA DHR10 PF18595.1 VBB27784.1 - 0.014 15.4 11.0 0.014 15.4 11.0 5.0 3 2 1 4 4 4 0 Designed helical repeat protein 10 domain Snapin_Pallidin PF14712.6 VBB27784.1 - 0.016 15.6 7.5 0.016 15.6 7.5 4.5 3 2 2 5 5 5 0 Snapin/Pallidin GAS PF13851.6 VBB27784.1 - 0.02 14.2 45.6 0.67 9.3 7.8 4.1 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 VBB27784.1 - 0.02 14.6 44.9 0.019 14.7 11.5 3.8 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.18 VBB27784.1 - 0.029 14.7 28.4 0.067 13.5 1.0 5.9 4 1 0 5 5 5 0 TSC-22/dip/bun family ATG16 PF08614.11 VBB27784.1 - 0.035 14.3 44.5 0.09 13.0 15.1 3.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 VBB27784.1 - 0.089 13.0 0.1 0.089 13.0 0.1 6.4 5 1 1 6 6 6 0 Homeobox associated leucine zipper DUF948 PF06103.11 VBB27784.1 - 0.11 12.8 14.6 0.19 12.0 1.1 4.2 3 2 1 4 4 3 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 VBB27784.1 - 0.14 12.5 18.9 0.19 12.1 1.4 5.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 VBB27784.1 - 0.15 12.0 32.2 0.96 9.4 1.6 5.8 2 2 2 5 5 5 0 Prefoldin subunit KASH_CCD PF14662.6 VBB27784.1 - 0.19 11.5 44.0 0.8 9.5 14.7 4.1 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Metal_resist PF13801.6 VBB27784.1 - 0.27 11.4 22.6 0.04 14.1 3.2 4.0 3 1 0 3 3 3 0 Heavy-metal resistance DUF4988 PF16378.5 VBB27784.1 - 0.31 10.7 5.5 5.4 6.6 1.3 3.2 2 0 0 2 2 2 0 Domain of unknown function FPP PF05911.11 VBB27784.1 - 0.37 8.9 34.6 0.23 9.6 13.1 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Pox_A_type_inc PF04508.12 VBB27784.1 - 0.51 10.3 10.3 0.23 11.4 0.9 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Surfac_D-trimer PF09006.11 VBB27784.1 - 0.57 10.1 5.6 15 5.6 0.1 3.9 3 1 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Herpes_UL6 PF01763.16 VBB27784.1 - 0.66 8.4 24.6 0.13 10.8 3.7 3.2 1 1 1 3 3 3 0 Herpesvirus UL6 like Prominin PF05478.11 VBB27784.1 - 0.72 7.7 23.8 0.61 8.0 7.7 2.2 1 1 1 2 2 2 0 Prominin HTH_Tnp_1 PF01527.20 VBB27784.1 - 0.76 10.1 0.0 0.76 10.1 0.0 4.6 6 1 0 6 6 2 0 Transposase Cep57_MT_bd PF06657.13 VBB27784.1 - 1.1 9.8 26.8 2 8.9 5.8 5.0 3 2 2 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DUF3450 PF11932.8 VBB27784.1 - 1.4 8.2 39.2 0.15 11.3 8.2 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 VBB27784.1 - 1.4 9.0 24.6 0.34 11.0 5.9 4.6 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) MAD PF05557.13 VBB27784.1 - 1.7 6.9 47.3 1 7.6 11.4 2.8 1 1 1 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 VBB27784.1 - 1.7 9.0 46.9 1.4 9.4 6.6 3.7 1 1 2 3 3 3 0 Fez1 bZIP_1 PF00170.21 VBB27784.1 - 1.8 8.7 32.1 0.34 11.0 1.1 5.9 5 1 0 5 5 5 0 bZIP transcription factor DUF3584 PF12128.8 VBB27784.1 - 1.9 5.9 46.0 0.14 9.7 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 VBB27784.1 - 2 8.2 20.5 1.6 8.5 1.7 3.7 1 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 VBB27784.1 - 2.2 8.3 44.1 2.4 8.2 5.3 3.6 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 VBB27784.1 - 7.8 6.5 17.2 9.4 6.3 4.1 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 VBB27784.1 - 8.4 6.5 35.5 1.3 9.1 1.7 5.6 3 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.8 VBB27784.1 - 8.6 6.5 20.3 2.1 8.5 0.8 4.9 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) RNase_PH PF01138.21 VBB27785.1 - 5.4e-18 65.8 0.0 7.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FSA_C PF10479.9 VBB27786.1 - 3.5e-22 78.3 11.4 5e-09 34.9 0.9 4.2 2 2 2 4 4 4 4 Fragile site-associated protein C-terminus UvsY PF11056.8 VBB27786.1 - 0.013 15.8 2.4 0.26 11.6 0.3 3.0 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY ABC2_membrane PF01061.24 VBB27787.1 - 1.3e-07 31.2 4.8 0.0001 21.8 0.1 3.1 3 1 1 4 4 4 2 ABC-2 type transporter GP3 PF03076.14 VBB27787.1 - 0.011 15.7 0.2 0.014 15.5 0.2 1.3 1 1 0 1 1 1 0 Equine arteritis virus GP3 COG4 PF08318.12 VBB27788.1 - 1.3e-77 261.2 6.6 2.4e-77 260.3 6.6 1.4 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 VBB27788.1 - 3.6e-06 26.1 0.5 3.6e-06 26.1 0.5 1.8 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Patched PF02460.18 VBB27789.1 - 1.6e-174 582.2 18.2 2e-174 581.9 18.2 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB27789.1 - 8.1e-38 129.7 4.5 8.1e-38 129.7 4.5 3.7 3 1 1 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 VBB27789.1 - 1.2e-06 26.5 1.5 2.1e-06 25.7 1.5 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 VBB27789.1 - 0.013 14.5 10.7 0.016 14.2 0.8 2.6 2 0 0 2 2 2 0 MMPL family SecD_SecF PF02355.16 VBB27789.1 - 1.3 8.4 20.4 0.023 14.1 11.9 2.5 2 1 0 2 2 2 0 Protein export membrane protein ETRAMP PF09716.10 VBB27789.1 - 5 7.2 8.5 0.73 9.9 0.4 3.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ARID PF01388.21 VBB27790.1 - 3.6e-18 66.0 0.0 9.4e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 VBB27790.1 - 4.4e-06 27.2 0.1 1.7e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain FOXP-CC PF16159.5 VBB27790.1 - 0.0012 19.4 12.2 0.28 11.9 1.4 2.8 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 VBB27790.1 - 0.099 12.8 3.1 0.15 12.2 0.6 2.4 2 1 1 3 3 3 0 Aberrant zinc-finger zf-Di19 PF05605.12 VBB27790.1 - 0.35 11.2 7.8 1.1 9.7 7.8 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Hist_deacetyl PF00850.19 VBB27791.1 - 4.8e-82 275.9 0.1 7.4e-82 275.3 0.0 1.3 2 0 0 2 2 2 1 Histone deacetylase domain Decorin_bind PF02352.15 VBB27792.1 - 0.17 12.2 0.1 0.36 11.1 0.0 1.5 2 0 0 2 2 2 0 Decorin binding protein Bromodomain PF00439.25 VBB27793.1 - 3.7e-07 30.1 0.0 2e-06 27.8 0.1 2.2 2 0 0 2 2 2 1 Bromodomain Pkinase_Tyr PF07714.17 VBB27794.1 - 6.8e-80 268.1 0.0 1e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB27794.1 - 2.9e-41 141.6 0.0 7.8e-41 140.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 VBB27794.1 - 0.0021 17.5 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TIG PF01833.24 VBB27794.1 - 0.0021 18.1 0.7 0.0044 17.1 0.2 1.8 2 0 0 2 2 2 1 IPT/TIG domain EphA2_TM PF14575.6 VBB27794.1 - 0.11 13.4 0.5 0.63 11.0 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 VBB27795.1 - 8.7e-28 96.7 0.0 4.6e-08 33.6 0.0 5.0 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 VBB27795.1 - 1.1e-22 80.0 0.0 1.6e-07 31.4 0.1 4.6 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 VBB27795.1 - 3.9e-21 74.9 0.2 1.3e-06 28.4 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB27795.1 - 1.3e-16 60.7 0.0 0.0027 18.0 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 VBB27795.1 - 1e-14 54.6 9.2 4.8e-05 23.5 0.1 7.2 7 2 1 8 8 8 3 Immunoglobulin V-set domain fn3 PF00041.21 VBB27795.1 - 1.6e-13 50.8 0.4 2.1e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Ig_6 PF18452.1 VBB27795.1 - 1.4e-07 31.0 0.1 0.64 9.6 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 VBB27795.1 - 0.00097 19.4 0.1 1.2 9.5 0.0 3.6 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 VBB27795.1 - 0.0045 17.0 0.1 1.1 9.3 0.0 3.5 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 VBB27795.1 - 0.015 15.3 0.0 3.4 7.8 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 VBB27795.1 - 0.023 15.3 0.2 1.8 9.2 0.0 2.8 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain OTU PF02338.19 VBB27796.1 - 0.00051 20.5 0.0 0.00078 19.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease HBB PF06777.11 VBB27797.1 - 3.2e-39 134.6 1.6 3.6e-35 121.4 0.4 2.7 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 VBB27797.1 - 1.6e-37 129.3 0.0 2.9e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain Cast PF10174.9 VBB27797.1 - 0.022 13.0 1.4 0.032 12.5 1.4 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Troponin PF00992.20 VBB27797.1 - 0.041 14.2 1.0 0.082 13.2 1.0 1.4 1 0 0 1 1 1 0 Troponin RhoGAP PF00620.27 VBB27798.1 - 4.2e-33 114.3 0.0 1.4e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 VBB27798.1 - 0.0031 18.1 0.0 0.0072 16.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain CCDC92 PF14916.6 VBB27799.1 - 5.4e-08 32.5 1.4 5.4e-08 32.5 1.4 2.5 2 0 0 2 2 2 1 Coiled-coil domain of unknown function KASH_CCD PF14662.6 VBB27799.1 - 0.008 16.0 17.1 0.31 10.8 8.4 2.4 2 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 VBB27799.1 - 0.0086 16.7 10.9 1.2 9.8 0.1 3.7 1 1 2 3 3 3 2 SlyX Pinin_SDK_memA PF04696.13 VBB27799.1 - 0.0098 15.9 6.2 0.0098 15.9 6.2 2.2 2 1 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Prismane PF03063.20 VBB27799.1 - 0.012 14.3 5.3 0.013 14.2 2.7 1.9 1 1 1 2 2 2 0 Prismane/CO dehydrogenase family Endonuc-MspI PF09208.10 VBB27799.1 - 0.02 14.3 4.4 0.035 13.5 4.4 1.3 1 0 0 1 1 1 0 Restriction endonuclease MspI Bcr-Abl_Oligo PF09036.10 VBB27799.1 - 0.042 13.9 6.8 0.24 11.4 2.3 3.2 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Rootletin PF15035.6 VBB27799.1 - 0.12 12.3 18.9 2.5 8.1 0.6 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Exonuc_VII_L PF02601.15 VBB27799.1 - 0.23 11.0 8.0 0.34 10.4 8.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SOGA PF11365.8 VBB27799.1 - 0.26 12.4 11.2 0.089 13.9 7.0 2.3 2 1 0 2 2 2 0 Protein SOGA YabA PF06156.13 VBB27799.1 - 0.29 11.8 14.2 0.1 13.2 5.9 2.8 2 1 1 3 3 2 0 Initiation control protein YabA KxDL PF10241.9 VBB27799.1 - 0.57 10.5 11.2 0.81 10.0 6.5 2.9 1 1 0 2 2 2 0 Uncharacterized conserved protein FCH PF00611.23 VBB27799.1 - 0.58 10.5 4.5 0.34 11.2 2.2 1.7 2 0 0 2 2 1 0 Fes/CIP4, and EFC/F-BAR homology domain AbiGi PF10899.8 VBB27799.1 - 0.74 9.6 5.6 6.4 6.6 0.9 2.7 3 0 0 3 3 3 0 Putative abortive phage resistance protein AbiGi, antitoxin TMPIT PF07851.13 VBB27799.1 - 1.1 8.4 10.6 2.6 7.2 5.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein CortBP2 PF09727.9 VBB27799.1 - 1.2 9.1 16.3 2.1 8.2 14.6 2.3 1 1 1 2 2 2 0 Cortactin-binding protein-2 INTS5_N PF14837.6 VBB27799.1 - 1.3 8.6 5.4 0.5 9.9 0.5 2.4 2 1 1 3 3 3 0 Integrator complex subunit 5 N-terminus Mod_r PF07200.13 VBB27799.1 - 1.5 8.9 15.4 10 6.2 15.4 2.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.6 VBB27799.1 - 4.4 7.5 20.0 1.2 9.3 12.9 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 VBB27799.1 - 5.3 5.8 19.0 0.28 10.0 11.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 VBB27799.1 - 8.3 6.5 18.2 5.1 7.2 16.2 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 VBB27799.1 - 8.4 6.8 18.8 0.92 9.9 7.8 3.5 3 1 1 4 4 4 0 Csm1 N-terminal domain CSN8_PSD8_EIF3K PF10075.9 VBB27800.1 - 1.5e-27 96.3 0.0 3.1e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family XLF PF09302.11 VBB27801.1 - 0.006 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Shufflon_N PF04917.12 VBB27801.1 - 0.051 13.0 0.1 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region IP_trans PF02121.18 VBB27802.1 - 5.8e-101 337.2 0.0 6.6e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF5358 PF17311.2 VBB27805.1 - 0.014 15.5 1.2 0.014 15.5 1.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5358) Thioredoxin PF00085.20 VBB27805.1 - 0.025 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin adh_short PF00106.25 VBB27806.1 - 3.2e-11 43.0 0.0 5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB27806.1 - 0.053 13.1 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SPRY PF00622.28 VBB27807.1 - 2.2e-16 60.1 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Iso_dh PF00180.20 VBB27808.1 - 3.6e-67 227.0 0.1 4.4e-67 226.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.32 VBB27809.1 - 3.4e-26 91.0 8.4 0.00018 22.2 0.2 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Renin_r PF07850.14 VBB27809.1 - 3.7e-25 88.4 0.2 8.9e-25 87.1 0.2 1.7 1 0 0 1 1 1 1 Renin receptor-like protein ANAPC4_WD40 PF12894.7 VBB27809.1 - 9e-06 25.9 0.1 2.8 8.3 0.0 4.7 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB27809.1 - 0.015 14.6 0.0 0.05 12.9 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 VBB27809.1 - 0.02 15.4 0.0 1.1 9.9 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Flot PF15975.5 VBB27809.1 - 0.17 12.1 0.2 0.46 10.7 0.2 1.7 1 0 0 1 1 1 0 Flotillin MH2 PF03166.14 VBB27810.1 - 1.7e-14 54.5 0.0 3.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 MH2 domain Peptidase_M14 PF00246.24 VBB27811.1 - 1.1e-62 212.4 0.0 6.1e-62 210.0 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase CarbopepD_reg_2 PF13715.6 VBB27811.1 - 6.5e-06 26.1 0.3 2.1e-05 24.4 0.2 1.9 2 0 0 2 2 2 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 VBB27811.1 - 0.00046 19.4 0.0 0.001 18.2 0.0 1.4 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Glyco_hydro_47 PF01532.20 VBB27812.1 - 3.8e-128 428.2 6.7 1.9e-122 409.5 0.6 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 DUF1048 PF06304.11 VBB27812.1 - 0.0022 18.4 1.7 0.35 11.3 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1048) DUF4131 PF13567.6 VBB27812.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) XendoU PF09412.10 VBB27815.1 - 1.9e-37 129.0 2.8 5.9e-25 88.0 0.3 2.0 1 1 1 2 2 2 2 Endoribonuclease XendoU Calponin PF00402.18 VBB27816.1 - 3.9e-11 42.4 0.2 3e-06 26.8 0.3 2.3 2 0 0 2 2 2 2 Calponin family repeat Homeodomain PF00046.29 VBB27817.1 - 9.1e-20 70.3 1.1 1.3e-19 69.8 1.1 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27817.1 - 0.018 14.9 0.1 0.045 13.7 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 VBB27817.1 - 0.15 11.6 0.9 0.23 11.0 0.9 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Importin_rep_3 PF18806.1 VBB27818.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat RR_TM4-6 PF06459.12 VBB27818.1 - 7.7 6.2 11.7 10 5.9 11.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bul1_C PF04426.12 VBB27819.1 - 0.69 9.3 9.1 0.26 10.6 0.1 2.2 2 0 0 2 2 2 0 Bul1 C terminus Spt20 PF12090.8 VBB27819.1 - 1.1 8.8 17.9 1.9 8.0 17.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF588 PF04535.12 VBB27820.1 - 0.0019 18.0 2.8 0.11 12.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF588) Tmemb_cc2 PF10267.9 VBB27820.1 - 7.2 5.6 5.4 12 4.9 5.4 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4131 PF13567.6 VBB27820.1 - 10 5.8 8.0 14 5.2 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 VBB27821.1 - 3.9e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ANAPC11 PF12861.7 VBB27822.1 - 2.3e-27 94.9 12.9 4.2e-27 94.0 12.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 VBB27822.1 - 1.2e-17 63.9 17.3 1.2e-17 63.9 17.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 VBB27822.1 - 0.0014 18.9 24.5 0.0036 17.6 20.7 3.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 VBB27822.1 - 0.03 14.2 15.9 0.15 12.0 15.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB27822.1 - 0.35 10.9 14.7 0.52 10.4 12.3 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Saf_2TM PF18303.1 VBB27823.1 - 1.5 8.4 4.8 0.45 10.1 0.2 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF202 PF02656.15 VBB27823.1 - 2.8 8.5 5.7 20 5.7 5.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Calponin PF00402.18 VBB27824.1 - 6.4e-69 227.1 42.7 1.8e-11 43.4 0.7 7.4 7 0 0 7 7 7 7 Calponin family repeat GYF_2 PF14237.6 VBB27825.1 - 9.5e-15 54.1 0.6 2e-14 53.1 0.6 1.6 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 VBB27825.1 - 8.4e-11 41.8 0.1 2.2e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain TTKRSYEDQ PF10212.9 VBB27825.1 - 3 6.7 12.6 0.017 14.2 1.8 2.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Mei5 PF10376.9 VBB27826.1 - 0.0098 15.8 5.9 0.018 14.9 5.9 1.4 1 0 0 1 1 1 1 Double-strand recombination repair protein Innexin PF00876.18 VBB27827.1 - 8.3e-122 406.8 14.2 9.5e-122 406.6 14.2 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 VBB27828.1 - 4.5e-90 302.5 11.0 8.3e-90 301.6 11.0 1.4 1 1 0 1 1 1 1 Innexin Yippee-Mis18 PF03226.14 VBB27829.1 - 0.31 11.3 7.6 0.47 10.7 0.1 3.6 4 0 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_4 PF13894.6 VBB27829.1 - 0.47 11.4 0.2 0.47 11.4 0.2 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB27829.1 - 0.77 10.3 11.6 0.42 11.1 1.4 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 VBB27829.1 - 1.3 9.2 6.5 23 5.2 0.4 3.9 3 0 0 3 3 3 0 Zinc ribbon domain Nup35_RRM_2 PF14605.6 VBB27830.1 - 4.6e-18 65.0 0.5 4.6e-14 52.1 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 VBB27830.1 - 8.4e-08 32.4 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM PF05172.13 VBB27830.1 - 0.0004 20.3 0.3 0.023 14.6 0.0 3.0 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 VBB27830.1 - 0.0011 18.9 2.1 0.0019 18.2 2.1 1.4 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 VBB27830.1 - 0.0028 17.4 0.1 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 VBB27830.1 - 0.0034 17.3 3.2 0.0054 16.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TMEM132 PF16070.5 VBB27831.1 - 5.6e-91 305.5 0.5 9.1e-91 304.7 0.5 1.4 1 0 0 1 1 1 1 Transmembrane protein family 132 HA2 PF04408.23 VBB27833.1 - 2.6e-23 82.4 0.2 2.6e-23 82.4 0.2 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 VBB27833.1 - 7.7e-22 77.5 0.0 3.1e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 VBB27833.1 - 1.4e-11 44.7 0.0 3.5e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 VBB27833.1 - 1.2e-06 28.9 0.0 5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 VBB27833.1 - 2.4e-06 27.5 0.0 5.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 VBB27833.1 - 0.001 19.4 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 VBB27833.1 - 0.0012 18.8 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 VBB27833.1 - 0.0072 16.0 0.0 0.02 14.5 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 VBB27833.1 - 0.09 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 VBB27833.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 VBB27833.1 - 0.13 11.9 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 VBB27833.1 - 0.13 11.9 0.0 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SH2 PF00017.24 VBB27834.1 - 3.6e-11 43.0 0.2 6.3e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 SH2 domain LBP_BPI_CETP_C PF02886.17 VBB27836.1 - 1.1e-52 178.9 0.2 1.2e-52 178.8 0.2 1.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain PP2C PF00481.21 VBB27837.1 - 0.0051 16.5 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C MIP-T3 PF10243.9 VBB27838.1 - 1.3e-34 118.6 0.6 1.3e-34 118.6 0.6 2.9 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 VBB27838.1 - 1.5e-21 76.9 12.3 1.5e-21 76.9 12.3 2.5 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region FUSC PF04632.12 VBB27838.1 - 0.13 10.8 1.3 0.18 10.3 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family XhlA PF10779.9 VBB27838.1 - 1.2 9.4 11.4 1.3 9.2 0.1 3.7 3 0 0 3 3 3 0 Haemolysin XhlA DUF4865 PF16157.5 VBB27838.1 - 2 8.4 7.6 1.4 8.8 0.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4865) Acyl-thio_N PF12590.8 VBB27838.1 - 2.6 8.6 6.8 4.1 8.0 1.9 2.7 2 0 0 2 2 2 0 Acyl-ATP thioesterase Apis_Csd PF11671.8 VBB27838.1 - 3.5 7.6 8.2 8.6 6.4 8.2 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Collagen PF01391.18 VBB27839.1 - 5.3e-25 86.9 64.4 1.3e-08 34.4 20.2 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB27840.1 - 7.9e-21 73.9 0.3 1e-20 73.5 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB27840.1 - 5.4e-17 61.3 93.3 1e-09 38.0 38.0 4.8 3 2 0 3 3 3 2 Collagen triple helix repeat (20 copies) COX14 PF14880.6 VBB27840.1 - 0.0059 16.4 2.5 0.0097 15.7 2.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly MH2 PF03166.14 VBB27841.1 - 6e-61 205.9 0.0 1.2e-60 204.9 0.0 1.5 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 VBB27841.1 - 0.042 13.6 0.0 0.097 12.5 0.0 1.6 1 1 0 1 1 1 0 Interferon-regulatory factor 3 MIS13 PF08202.11 VBB27841.1 - 0.092 12.0 0.5 0.13 11.5 0.5 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family IF-2B PF01008.17 VBB27842.1 - 4.5e-65 219.7 0.0 5.5e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Thr_dehydrat_C PF00585.18 VBB27842.1 - 0.16 11.8 0.1 2.9 7.7 0.0 2.6 2 1 1 3 3 3 0 C-terminal regulatory domain of Threonine dehydratase SWIB PF02201.18 VBB27843.1 - 4.1e-19 68.2 0.0 1e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 VBB27843.1 - 1.2e-07 31.5 2.2 1.2e-07 31.5 2.2 1.8 2 0 0 2 2 2 1 DEK C terminal domain DUF2766 PF10964.8 VBB27843.1 - 0.086 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) RNA_polI_A34 PF08208.11 VBB27843.1 - 6.4 6.8 22.9 0.37 10.8 2.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Ion_trans PF00520.31 VBB27844.1 - 1.5e-35 122.6 6.8 2e-35 122.2 6.8 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 VBB27844.1 - 3.7e-13 49.4 0.0 9.3e-13 48.1 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 VBB27844.1 - 3.2e-10 39.8 2.5 3.2e-10 39.8 2.5 2.3 3 0 0 3 3 3 1 Ion channel IRK PF01007.20 VBB27844.1 - 1.2 8.9 6.8 9.7 6.0 6.8 2.2 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain CPSF_A PF03178.15 VBB27846.1 - 5.8e-71 239.4 0.0 2.6e-70 237.3 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region DUF1126 PF06565.12 VBB27846.1 - 0.03 14.2 0.0 0.14 12.0 0.0 2.2 1 0 0 1 1 1 0 DUF1126 PH-like domain GDPD PF03009.17 VBB27847.1 - 1.4e-67 228.2 0.0 1.9e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 VBB27847.1 - 2.3e-05 24.2 0.0 5.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain COG6 PF06419.11 VBB27848.1 - 2.1e-138 462.3 13.4 4.4e-138 461.2 13.4 1.4 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 VBB27848.1 - 0.0027 17.6 4.5 0.0045 16.9 2.4 2.4 1 1 0 1 1 1 1 Sec34-like family Fmp27_WPPW PF10359.9 VBB27848.1 - 0.012 14.5 2.6 0.025 13.4 2.6 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ATG16 PF08614.11 VBB27848.1 - 0.075 13.2 8.0 0.69 10.1 8.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GCSF PF16647.5 VBB27848.1 - 0.1 12.5 0.4 0.28 11.0 0.4 1.8 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Muted PF14942.6 VBB27848.1 - 1.2 9.5 8.1 0.44 10.9 2.5 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fes1 PF08609.10 VBB27848.1 - 1.7 9.6 7.0 2.6 9.0 0.6 3.1 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 Nup54 PF13874.6 VBB27848.1 - 1.8 8.7 6.9 4.8 7.3 3.0 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 NleF_casp_inhib PF16809.5 VBB27848.1 - 2.1 8.2 8.7 1.9 8.4 5.7 2.2 2 0 0 2 2 2 0 NleF caspase inhibitor YabA PF06156.13 VBB27848.1 - 2.3 8.9 5.4 1.5 9.5 2.0 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 VBB27848.1 - 9.1 6.5 12.0 0.88 9.8 3.7 2.7 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Spectrin PF00435.21 VBB27848.1 - 9.8 6.7 10.7 13 6.3 0.7 3.3 4 0 0 4 4 4 0 Spectrin repeat tRNA-synt_2 PF00152.20 VBB27849.1 - 1.1e-99 333.6 0.0 1.4e-99 333.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 VBB27849.1 - 4.7e-14 52.1 0.1 1.6e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain BOF PF04076.13 VBB27849.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein tRNA_anti_2 PF13742.6 VBB27849.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF1565 PF07602.11 VBB27849.1 - 0.19 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Mito_fiss_reg PF05308.11 VBB27849.1 - 0.25 11.4 1.6 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_tran_28_C PF04101.16 VBB27851.1 - 5e-23 81.9 0.0 7.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Whirly PF08536.11 VBB27851.1 - 0.035 13.9 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Whirly transcription factor SAS-6_N PF16531.5 VBB27852.1 - 1.1e-11 45.1 1.2 9.5e-11 42.1 0.1 2.5 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal ATG16 PF08614.11 VBB27852.1 - 3.7e-06 27.3 40.8 0.00072 19.8 29.0 3.4 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 VBB27852.1 - 1.1e-05 24.5 49.6 0.00039 19.4 9.3 3.1 1 1 1 3 3 3 2 Spc7 kinetochore protein Prefoldin_2 PF01920.20 VBB27852.1 - 0.00016 21.6 42.4 0.14 12.1 6.6 5.5 3 2 2 5 5 5 3 Prefoldin subunit TPR_MLP1_2 PF07926.12 VBB27852.1 - 0.00018 21.6 49.2 0.0012 18.9 9.6 4.8 2 1 3 5 5 4 2 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 VBB27852.1 - 0.00036 20.7 49.9 0.23 11.5 5.0 3.3 1 1 2 3 3 3 3 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 VBB27852.1 - 0.0018 17.9 46.1 0.31 10.6 19.8 3.2 1 1 2 3 3 3 3 Intermediate filament protein Fez1 PF06818.15 VBB27852.1 - 0.0018 18.7 43.3 0.26 11.7 16.1 3.8 1 1 2 3 3 3 2 Fez1 Mod_r PF07200.13 VBB27852.1 - 0.0019 18.3 40.9 0.074 13.2 19.2 3.3 1 1 2 3 3 3 2 Modifier of rudimentary (Mod(r)) protein Golgin_A5 PF09787.9 VBB27852.1 - 0.0021 17.6 42.5 0.15 11.5 19.2 2.4 1 1 1 2 2 2 2 Golgin subfamily A member 5 ZapB PF06005.12 VBB27852.1 - 0.0034 17.8 50.2 0.049 14.1 2.2 5.7 3 1 3 6 6 5 3 Cell division protein ZapB HAP1_N PF04849.13 VBB27852.1 - 0.0057 15.9 27.1 0.0057 15.9 27.1 2.8 1 1 1 2 2 2 1 HAP1 N-terminal conserved region DUF4618 PF15397.6 VBB27852.1 - 0.0059 16.1 37.6 0.025 14.0 22.3 2.8 1 1 2 3 3 3 3 Domain of unknown function (DUF4618) DUF3450 PF11932.8 VBB27852.1 - 0.0076 15.6 30.7 0.25 10.6 5.6 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) DivIC PF04977.15 VBB27852.1 - 0.011 15.5 35.9 0.28 11.0 1.1 5.7 3 1 2 5 5 5 0 Septum formation initiator GAS PF13851.6 VBB27852.1 - 0.012 14.9 46.5 0.11 11.8 7.9 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding YscO PF07321.12 VBB27852.1 - 0.014 15.3 9.3 0.014 15.3 9.3 4.2 2 1 2 4 4 4 0 Type III secretion protein YscO JIP_LZII PF16471.5 VBB27852.1 - 0.021 15.0 7.6 0.021 15.0 7.6 5.5 3 1 2 5 5 5 0 JNK-interacting protein leucine zipper II Laminin_II PF06009.12 VBB27852.1 - 0.022 14.8 24.5 0.17 11.9 7.9 2.7 1 1 0 2 2 2 0 Laminin Domain II bZIP_1 PF00170.21 VBB27852.1 - 0.025 14.7 36.0 0.26 11.4 2.3 5.6 4 1 1 5 5 5 0 bZIP transcription factor CENP-H PF05837.12 VBB27852.1 - 0.031 14.7 42.1 0.19 12.2 13.0 3.9 1 1 3 4 4 4 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 VBB27852.1 - 0.033 14.2 53.0 0.32 11.0 7.3 3.6 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 VBB27852.1 - 0.036 13.3 45.9 0.79 8.8 45.7 3.3 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Ntox50 PF15542.6 VBB27852.1 - 0.053 14.3 0.1 0.053 14.3 0.1 2.7 3 1 0 3 3 1 0 Bacterial toxin 50 DUF4201 PF13870.6 VBB27852.1 - 0.067 12.9 46.6 0.22 11.2 26.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) YabA PF06156.13 VBB27852.1 - 0.12 13.0 39.7 0.19 12.4 1.8 5.3 3 1 1 4 4 2 0 Initiation control protein YabA DUF1664 PF07889.12 VBB27852.1 - 0.14 12.2 28.4 0.21 11.7 7.9 3.8 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 VBB27852.1 - 0.15 12.6 58.8 0.54 10.8 18.0 4.2 2 1 3 5 5 4 0 Apg6 coiled-coil region DUF3584 PF12128.8 VBB27852.1 - 0.16 9.5 35.6 0.28 8.7 35.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SHE3 PF17078.5 VBB27852.1 - 0.2 11.4 42.9 0.039 13.7 13.5 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Atg14 PF10186.9 VBB27852.1 - 0.21 10.6 37.5 0.44 9.6 13.8 3.6 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Snapin_Pallidin PF14712.6 VBB27852.1 - 0.27 11.7 34.4 0.45 11.0 1.1 5.2 2 1 4 6 6 6 0 Snapin/Pallidin AAA_13 PF13166.6 VBB27852.1 - 0.28 9.8 35.2 0.14 10.7 24.6 2.2 1 1 1 2 2 2 0 AAA domain Med9 PF07544.13 VBB27852.1 - 0.34 11.0 31.7 1.4 9.0 0.9 5.0 3 2 2 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 DHR10 PF18595.1 VBB27852.1 - 0.37 10.9 50.4 0.41 10.7 5.3 5.3 2 1 3 5 5 4 0 Designed helical repeat protein 10 domain CALCOCO1 PF07888.11 VBB27852.1 - 0.42 9.4 39.3 0.9 8.3 29.7 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF948 PF06103.11 VBB27852.1 - 0.45 10.8 16.4 2.8 8.3 4.4 3.7 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 VBB27852.1 - 0.47 9.4 35.6 0.27 10.2 18.2 2.6 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 HrpB7 PF09486.10 VBB27852.1 - 0.48 10.8 23.5 6.5 7.1 0.3 3.4 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.6 VBB27852.1 - 0.53 9.9 47.0 1 9.0 14.1 3.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KLRAQ PF10205.9 VBB27852.1 - 0.66 10.2 38.0 0.23 11.7 2.0 5.1 3 1 2 5 5 5 0 Predicted coiled-coil domain-containing protein CREPT PF16566.5 VBB27852.1 - 0.93 9.7 36.6 2.5 8.2 4.6 3.8 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2935 PF11155.8 VBB27852.1 - 0.99 9.7 12.7 96 3.3 9.1 4.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) WEMBL PF05701.11 VBB27852.1 - 1 8.0 39.3 2.5 6.7 4.8 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Seryl_tRNA_N PF02403.22 VBB27852.1 - 1.1 9.5 37.8 0.061 13.6 3.8 5.2 2 1 3 5 5 4 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 VBB27852.1 - 1.3 9.6 24.5 0.44 11.1 6.8 4.5 1 1 3 5 5 4 0 Nucleopolyhedrovirus P10 protein Rootletin PF15035.6 VBB27852.1 - 1.4 8.9 43.4 38 4.2 25.4 3.0 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.11 VBB27852.1 - 1.5 8.9 40.5 0.033 14.3 5.0 4.6 2 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 VBB27852.1 - 1.6 8.2 50.9 0.5 9.8 11.4 3.2 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 VBB27852.1 - 1.9 7.8 25.5 2.2 7.6 19.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 VBB27852.1 - 2.2 7.5 43.9 2.2 7.6 11.5 3.0 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) PspA_IM30 PF04012.12 VBB27852.1 - 2.3 7.8 30.6 4.4 6.8 13.2 3.5 1 1 2 3 3 2 0 PspA/IM30 family Fib_alpha PF08702.10 VBB27852.1 - 2.5 8.3 32.2 0.83 9.8 8.5 3.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 VBB27852.1 - 2.5 6.2 40.6 9.1 4.3 29.7 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Cnn_1N PF07989.11 VBB27852.1 - 2.8 8.1 41.7 0.6 10.3 1.7 5.6 2 1 3 5 5 5 0 Centrosomin N-terminal motif 1 DUF812 PF05667.11 VBB27852.1 - 3.3 6.5 42.1 0.46 9.3 19.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 VBB27852.1 - 3.6 8.0 34.0 0.58 10.6 1.3 5.9 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 VBB27852.1 - 3.7 7.0 39.9 2.5 7.5 24.5 2.4 1 1 1 2 2 2 0 Leucine zipper T3SSipB PF16535.5 VBB27852.1 - 4 7.9 17.1 4.1 7.9 1.7 3.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB ERM PF00769.19 VBB27852.1 - 4.6 7.0 45.0 38 4.0 5.9 3.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fzo_mitofusin PF04799.13 VBB27852.1 - 5.5 6.5 23.5 2.6 7.6 5.7 3.6 2 1 1 3 3 3 0 fzo-like conserved region HOOK PF05622.12 VBB27852.1 - 6.4 4.8 45.9 7.9 4.5 38.3 2.3 1 1 1 2 2 2 0 HOOK protein LPP PF04728.13 VBB27852.1 - 6.6 7.2 20.7 28 5.2 1.1 5.3 2 2 1 3 3 3 0 Lipoprotein leucine-zipper ADIP PF11559.8 VBB27852.1 - 6.7 6.8 42.1 0.68 10.0 4.8 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.13 VBB27852.1 - 6.9 6.8 34.8 0.34 11.0 4.1 4.2 1 1 2 3 3 3 0 DivIVA protein SlyX PF04102.12 VBB27852.1 - 10 6.9 28.9 2.3 8.9 5.0 4.9 3 1 2 5 5 3 0 SlyX DNA_methylase PF00145.17 VBB27853.1 - 1.3e-27 97.1 0.0 6.8e-27 94.7 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Lectin_C PF00059.21 VBB27854.1 - 1e-12 48.7 4.3 1.6e-12 48.1 4.3 1.3 1 0 0 1 1 1 1 Lectin C-type domain Pkinase PF00069.25 VBB27855.1 - 6.1e-68 229.0 0.0 6.9e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27855.1 - 2.1e-48 164.9 0.0 2.6e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB27855.1 - 5e-06 26.0 0.0 2.7e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB27855.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB27855.1 - 0.093 12.6 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family TH1 PF04858.13 VBB27856.1 - 3.7e-86 290.0 1.2 5e-86 289.6 1.2 1.1 1 0 0 1 1 1 1 TH1 protein LpqV PF17301.2 VBB27856.1 - 0.074 13.3 1.1 0.46 10.7 2.1 1.8 2 0 0 2 2 2 0 Putative lipoprotein LpqV SR-25 PF10500.9 VBB27856.1 - 2.4 7.7 15.6 0.31 10.6 11.5 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Na_K-ATPase PF00287.18 VBB27858.1 - 1.4e-16 60.5 0.8 2.5e-16 59.7 0.8 1.3 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain 7TM-7TMR_HD PF07698.11 VBB27858.1 - 0.037 13.8 0.6 0.057 13.2 0.6 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Poxvirus_B22R_N PF13169.6 VBB27858.1 - 0.069 13.7 1.5 2.8 8.5 0.2 3.0 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal fn2 PF00040.19 VBB27858.1 - 0.094 13.0 1.5 0.57 10.5 1.5 2.4 1 1 0 1 1 1 0 Fibronectin type II domain Kinesin PF00225.23 VBB27860.1 - 5.3e-115 383.9 0.3 1.3e-114 382.6 0.3 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 VBB27860.1 - 1.3e-29 103.1 0.9 3.3e-29 101.7 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3694 PF12473.8 VBB27860.1 - 2.3e-25 90.1 0.0 7e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 VBB27860.1 - 3e-21 76.4 6.8 6.2e-17 62.3 0.4 3.9 4 1 1 5 5 5 2 Kinesin-associated KIF1B PF12423.8 VBB27860.1 - 1.6e-09 38.0 1.0 7.3e-09 35.9 1.0 2.3 1 1 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 VBB27860.1 - 1.6e-05 25.1 0.1 6.7e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 VBB27860.1 - 5.3e-05 23.5 0.2 0.00059 20.1 0.1 2.9 3 0 0 3 3 3 1 FHA domain DUF3585 PF12130.8 VBB27860.1 - 0.00097 19.3 0.8 0.00097 19.3 0.8 3.2 3 0 0 3 3 2 1 Bivalent Mical/EHBP Rab binding domain C2-C2_1 PF11618.8 VBB27860.1 - 0.013 15.6 0.7 0.54 10.3 0.0 3.0 3 0 0 3 3 3 0 First C2 domain of RPGR-interacting protein 1 Ead_Ea22 PF13935.6 VBB27860.1 - 0.013 16.1 3.4 3.5 8.3 0.1 2.9 3 0 0 3 3 3 0 Ead/Ea22-like protein FtsK_SpoIIIE PF01580.18 VBB27860.1 - 0.036 13.4 2.3 2.3 7.5 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family Mobilization_B PF17511.2 VBB27860.1 - 0.13 12.6 0.7 0.38 11.1 0.7 1.7 1 0 0 1 1 1 0 Mobilization protein B Tsc35 PF15079.6 VBB27860.1 - 0.18 11.4 1.8 1.1 8.7 1.1 2.3 2 0 0 2 2 2 0 Testis-specific protein 35 Cep57_MT_bd PF06657.13 VBB27860.1 - 5.8 7.4 7.7 2.6 8.5 4.2 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MAM PF00629.23 VBB27861.1 - 2.1e-11 44.0 0.9 0.025 14.5 0.0 5.3 4 2 0 5 5 5 4 MAM domain, meprin/A5/mu MIF4G PF02854.19 VBB27862.1 - 1.5e-27 96.6 16.9 7e-15 55.2 0.1 4.2 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 VBB27862.1 - 1.2e-12 48.7 0.3 1.2e-12 48.7 0.3 3.3 2 1 1 3 3 3 1 Up-frameshift suppressor 2 MvaI_BcnI PF15515.6 VBB27862.1 - 0.024 14.4 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family ComR_TPR PF18710.1 VBB27862.1 - 0.031 13.8 1.8 0.48 9.9 0.1 3.2 3 0 0 3 3 3 0 ComR tetratricopeptide IKKbetaNEMObind PF12179.8 VBB27862.1 - 0.18 11.9 1.8 39 4.4 0.1 4.6 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain Arf PF00025.21 VBB27864.1 - 2.3e-79 264.9 0.1 2.6e-79 264.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB27864.1 - 3.4e-14 53.1 0.0 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 VBB27864.1 - 3.4e-14 52.8 1.1 2.7e-10 39.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 VBB27864.1 - 6.9e-14 51.7 0.0 8.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 VBB27864.1 - 2e-12 47.0 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 VBB27864.1 - 1.9e-11 43.8 0.0 2.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB27864.1 - 3.2e-06 27.2 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 VBB27864.1 - 0.004 16.5 0.4 0.01 15.2 0.4 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Motile_Sperm PF00635.26 VBB27865.1 - 7.9e-21 74.0 0.2 3.2e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain SCP2 PF02036.17 VBB27865.1 - 1.8e-11 44.4 0.0 5.8e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 SCP-2 sterol transfer family Band_7 PF01145.25 VBB27865.1 - 8.3e-10 39.0 1.8 2.2e-09 37.6 0.3 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Alkyl_sulf_C PF14864.6 VBB27865.1 - 0.0075 16.5 0.0 0.033 14.5 0.0 2.1 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal FH2 PF02181.23 VBB27866.1 - 5.4e-87 292.3 11.9 1e-86 291.4 11.9 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 VBB27866.1 - 1.3e-37 129.3 1.3 1.3e-37 129.3 1.3 3.8 4 2 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 VBB27866.1 - 9.6e-23 80.7 4.7 4.1e-21 75.4 0.3 2.7 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain DUF641 PF04859.12 VBB27866.1 - 0.0049 17.2 3.8 0.89 9.9 0.2 3.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) WXG100 PF06013.12 VBB27866.1 - 0.24 11.7 2.3 0.65 10.3 0.4 2.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF3322 PF11795.8 VBB27866.1 - 0.62 10.0 5.4 0.61 10.1 0.6 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Bcr-Abl_Oligo PF09036.10 VBB27866.1 - 0.66 10.0 3.9 0.57 10.2 0.3 2.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain G_glu_transpept PF01019.21 VBB27867.1 - 1.9e-155 518.6 0.0 2.2e-155 518.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MRP-S28 PF10213.9 VBB27869.1 - 2.4e-21 76.5 0.3 1.7e-20 73.7 0.3 2.3 2 1 0 2 2 2 1 Mitochondrial ribosomal subunit protein Neuro_bHLH PF12533.8 VBB27870.1 - 4.9e-09 37.4 19.9 4.9e-09 37.4 19.9 1.8 1 1 1 2 2 2 1 Neuronal helix-loop-helix transcription factor RPN2_C PF18004.1 VBB27870.1 - 0.0011 18.9 1.5 0.0015 18.5 1.5 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4770 PF15994.5 VBB27870.1 - 0.012 15.8 10.5 0.017 15.4 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Peptidase_U57 PF05582.12 VBB27870.1 - 0.013 14.7 6.9 0.018 14.3 6.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Presenilin PF01080.17 VBB27870.1 - 0.014 14.2 4.9 0.013 14.3 4.9 1.2 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 VBB27870.1 - 0.02 14.5 0.4 0.028 14.1 0.4 1.3 1 0 0 1 1 1 0 FAM176 family eIF-3_zeta PF05091.12 VBB27870.1 - 0.026 13.5 8.5 0.029 13.4 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Folate_carrier PF01770.18 VBB27870.1 - 0.053 12.3 3.8 0.084 11.6 3.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier Het-C PF07217.11 VBB27870.1 - 0.055 12.0 4.6 0.061 11.9 4.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C EPL1 PF10513.9 VBB27870.1 - 0.079 13.3 6.7 0.09 13.2 6.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like CobT PF06213.12 VBB27870.1 - 0.087 12.2 9.9 0.11 11.8 9.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 VBB27870.1 - 0.1 11.3 5.3 0.11 11.2 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 VBB27870.1 - 0.12 12.2 7.0 0.15 11.8 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABC2_membrane_2 PF12679.7 VBB27870.1 - 0.15 11.3 0.4 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein EIIBC-GUT_N PF03612.14 VBB27870.1 - 0.26 11.0 7.1 0.069 12.9 4.0 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus PepSY_TM PF03929.16 VBB27870.1 - 0.29 10.8 1.6 0.29 10.7 1.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM region ALMT PF11744.8 VBB27870.1 - 0.46 9.3 5.8 0.45 9.3 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AIF_C PF14721.6 VBB27870.1 - 0.48 10.8 5.9 0.92 9.9 5.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.6 VBB27870.1 - 0.65 7.8 26.3 0.73 7.7 26.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Orf78 PF06024.12 VBB27870.1 - 1.4 9.2 4.7 3.5 8.0 4.7 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF4407 PF14362.6 VBB27870.1 - 2.1 7.6 9.9 2.6 7.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 VBB27870.1 - 3.2 5.9 22.2 3.5 5.8 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.32 VBB27871.1 - 2e-27 94.9 33.3 0.00021 22.0 0.6 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat Ribosomal_S28e PF01200.18 VBB27872.1 - 6.3e-30 103.0 0.2 1.1e-29 102.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S28e SSrecog PF03531.14 VBB27872.1 - 1.5e-26 92.1 0.1 1.1e-25 89.3 0.0 2.5 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 VBB27872.1 - 2.4e-24 85.5 0.1 4.4e-23 81.5 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like HMG_box PF00505.19 VBB27872.1 - 3.4e-15 56.2 8.8 3.4e-15 56.2 8.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box POB3_N PF17292.2 VBB27872.1 - 6.5e-15 55.3 0.1 1.4e-12 47.9 0.0 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain HMG_box_2 PF09011.10 VBB27872.1 - 1.5e-11 44.7 8.6 7.6e-11 42.5 8.6 2.3 1 0 0 1 1 1 1 HMG-box domain PID PF00640.23 VBB27873.1 - 7e-29 100.7 0.1 1.1e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 VBB27873.1 - 1.4e-07 31.7 0.1 3.1e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 VBB27873.1 - 8.4e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MIS13 PF08202.11 VBB27873.1 - 0.0023 17.3 0.1 0.0037 16.6 0.1 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Herpes_BLRF2 PF05812.12 VBB27873.1 - 0.094 12.9 0.9 0.8 9.9 0.2 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein PEX-2N PF09263.10 VBB27873.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Pkinase PF00069.25 VBB27874.1 - 7.1e-67 225.5 0.0 1.2e-66 224.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27874.1 - 3.7e-31 108.4 0.0 5.7e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PDGF PF00341.17 VBB27874.1 - 5.3e-09 36.3 6.5 5.3e-09 36.3 6.5 2.2 2 0 0 2 2 2 1 PDGF/VEGF domain Haspin_kinase PF12330.8 VBB27874.1 - 0.0035 16.3 0.1 0.016 14.2 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 VBB27874.1 - 0.14 11.5 0.3 0.27 10.5 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 VBB27875.1 - 2.6e-66 219.6 6.0 6e-24 83.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial20 PF08256.11 VBB27875.1 - 0.69 10.6 7.7 39 5.2 0.1 4.7 4 0 0 4 4 4 0 Aurein-like antibiotic peptide ABC_tran PF00005.27 VBB27876.1 - 5.5e-48 163.0 0.3 1.9e-23 83.5 0.0 3.0 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 VBB27876.1 - 1.2e-21 77.8 0.4 0.00033 20.6 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 VBB27876.1 - 1.5e-20 73.0 5.3 1.5e-20 73.0 5.3 3.8 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 VBB27876.1 - 2.5e-11 43.4 0.1 4.6e-05 23.0 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 VBB27876.1 - 1.6e-08 34.1 0.1 0.008 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 VBB27876.1 - 1.5e-07 31.5 4.4 0.011 15.4 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 VBB27876.1 - 1e-06 29.4 0.0 0.028 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 VBB27876.1 - 4.9e-06 27.0 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 VBB27876.1 - 7.5e-06 26.0 0.3 0.19 11.8 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 VBB27876.1 - 9e-06 26.0 0.0 0.12 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 VBB27876.1 - 1.2e-05 24.6 0.0 0.012 14.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.6 VBB27876.1 - 4e-05 23.8 0.4 0.28 11.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 VBB27876.1 - 7.9e-05 22.6 0.0 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 VBB27876.1 - 8.7e-05 22.8 0.1 0.5 10.6 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 VBB27876.1 - 9.5e-05 23.0 0.4 0.013 16.0 0.1 4.0 4 1 0 4 4 2 2 AAA domain NACHT PF05729.12 VBB27876.1 - 0.00015 21.7 0.1 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_27 PF13514.6 VBB27876.1 - 0.00051 19.7 2.3 1.7 8.2 0.0 3.4 2 1 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 VBB27876.1 - 0.0012 18.9 0.5 1.1 9.2 0.0 3.5 2 1 0 3 3 3 1 Dynamin family AAA_30 PF13604.6 VBB27876.1 - 0.0015 18.3 0.0 1.1 9.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain GrpE PF01025.19 VBB27876.1 - 0.002 17.8 2.0 0.002 17.8 2.0 2.7 3 0 0 3 3 3 1 GrpE AAA PF00004.29 VBB27876.1 - 0.0023 18.4 0.0 3.3 8.2 0.0 3.6 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 VBB27876.1 - 0.0028 17.4 0.0 0.7 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 VBB27876.1 - 0.0029 17.6 0.0 1.8 8.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 VBB27876.1 - 0.004 17.5 0.0 1.7 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.6 VBB27876.1 - 0.011 16.2 3.6 0.62 10.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 VBB27876.1 - 0.013 15.4 0.2 6.1 6.6 0.0 2.9 3 0 0 3 3 3 0 MukB N-terminal PduV-EutP PF10662.9 VBB27876.1 - 0.016 15.0 0.0 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KapB PF08810.10 VBB27876.1 - 0.018 15.2 2.0 0.1 12.8 0.0 3.0 3 0 0 3 3 3 0 Kinase associated protein B cobW PF02492.19 VBB27876.1 - 0.02 14.5 0.0 7.8 6.1 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhetRS_B1 PF18262.1 VBB27876.1 - 0.024 14.9 0.1 0.17 12.2 0.0 2.5 2 1 0 2 2 1 0 Phe-tRNA synthetase beta subunit B1 domain AAA_25 PF13481.6 VBB27876.1 - 0.027 14.0 0.0 2.1 7.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 VBB27876.1 - 0.033 14.4 0.0 7.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 VBB27876.1 - 0.057 13.4 0.3 10 6.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 VBB27876.1 - 0.059 13.1 0.0 7.4 6.3 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 VBB27876.1 - 0.067 13.2 0.0 8.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 VBB27876.1 - 0.074 12.2 0.1 7.1 5.7 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 VBB27876.1 - 0.082 12.8 0.0 4.1 7.3 0.0 2.7 2 1 0 2 2 2 0 NTPase Arf PF00025.21 VBB27876.1 - 0.089 12.2 0.3 13 5.2 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_7 PF12775.7 VBB27876.1 - 0.11 11.9 0.0 17 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 VBB27876.1 - 0.12 12.3 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 VBB27876.1 - 0.36 9.8 2.3 3.9 6.4 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 VBB27876.1 - 0.65 10.1 8.5 2.9 7.9 0.0 3.7 4 1 1 5 5 3 0 Helicase HerA, central domain EF-hand_7 PF13499.6 VBB27877.1 - 2.4e-15 56.7 2.2 4.7e-10 39.8 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB27877.1 - 2.4e-12 45.5 2.0 0.0011 18.4 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 VBB27877.1 - 3.6e-12 45.2 1.1 7.9e-05 22.3 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 VBB27877.1 - 2.8e-09 37.2 0.1 0.0012 19.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 VBB27877.1 - 7.7e-08 32.1 3.8 3.5e-05 23.5 0.4 3.8 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB27877.1 - 0.05 13.1 3.7 0.059 12.9 0.1 2.9 4 0 0 4 4 4 0 EF hand ATP-cone PF03477.16 VBB27877.1 - 0.074 13.6 0.3 0.33 11.5 0.1 2.2 1 1 1 2 2 2 0 ATP cone domain Methyltransf_16 PF10294.9 VBB27878.1 - 7.3e-20 71.4 0.2 1.4e-19 70.5 0.1 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 VBB27878.1 - 5.9e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 VBB27878.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 VBB27878.1 - 0.011 16.4 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FAM86 PF14904.6 VBB27878.1 - 0.018 15.1 0.2 0.04 14.0 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function N_Asn_amidohyd PF14736.6 VBB27878.1 - 0.059 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Methyltransf_31 PF13847.6 VBB27878.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 VBB27878.1 - 0.075 12.4 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TGS PF02824.21 VBB27881.1 - 1.4e-20 73.1 0.0 2.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 VBB27881.1 - 2.6e-15 56.5 0.0 6.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 VBB27881.1 - 1e-14 54.4 0.0 2.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 VBB27881.1 - 6.5e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 VBB27881.1 - 0.072 13.2 0.0 2.3 8.3 0.0 2.3 1 1 1 2 2 2 0 Dynamin family zf-ZPR1 PF03367.13 VBB27881.1 - 0.16 11.9 0.0 1.2 9.0 0.0 2.1 3 0 0 3 3 3 0 ZPR1 zinc-finger domain PX PF00787.24 VBB27882.1 - 1.5e-14 54.0 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 VBB27882.1 - 0.012 15.0 0.0 0.11 11.9 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain SF3b10 PF07189.11 VBB27883.1 - 5.3e-34 116.2 0.6 2.3e-33 114.2 0.0 2.4 2 0 0 2 2 2 1 Splicing factor 3B subunit 10 (SF3b10) DASH_Dam1 PF08653.10 VBB27883.1 - 0.037 13.8 3.2 0.12 12.2 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Gliadin PF13016.6 VBB27883.1 - 0.04 14.3 0.2 0.22 11.9 0.2 2.3 1 0 0 1 1 1 0 Cys-rich Gliadin N-terminal HALZ PF02183.18 VBB27883.1 - 0.053 13.8 6.8 0.19 12.0 0.2 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper CX PF01705.19 VBB27884.1 - 5e-16 59.0 8.8 7.1e-16 58.5 8.8 1.2 1 0 0 1 1 1 1 CX module Conotoxin_I2 PF17557.2 VBB27884.1 - 0.037 14.1 7.4 0.083 13.0 7.4 1.5 1 0 0 1 1 1 0 I2-superfamily conotoxins 7TM_GPCR_Srx PF10328.9 VBB27885.1 - 1e-30 107.3 19.0 1.2e-30 107.1 19.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 VBB27885.1 - 3.7e-08 33.0 10.1 5e-08 32.6 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3043 PF11241.8 VBB27887.1 - 0.16 12.0 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PPTA PF01239.22 VBB27888.1 - 2.7e-31 106.4 13.1 2.7e-07 30.1 0.1 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 VBB27888.1 - 0.0069 16.8 2.1 0.84 10.1 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) SLATT_4 PF18186.1 VBB27888.1 - 0.028 14.1 0.3 0.071 12.7 0.3 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 NAD_binding_6 PF08030.12 VBB27888.1 - 2.4 8.3 4.0 14 5.7 0.6 2.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Homeodomain PF00046.29 VBB27889.1 - 3.6e-20 71.6 1.2 6.5e-20 70.7 1.2 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 VBB27889.1 - 9.9e-16 57.7 4.2 1.8e-15 56.9 4.2 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 VBB27889.1 - 0.00045 20.1 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Zn_ribbon_17 PF17120.5 VBB27889.1 - 0.39 10.4 5.0 0.84 9.3 5.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 VBB27889.1 - 0.57 10.5 4.6 2.2 8.6 0.8 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.9 VBB27889.1 - 1 9.8 4.1 12 6.4 3.5 2.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 STAR_dimer PF16544.5 VBB27890.1 - 6.2e-24 83.3 0.2 1.1e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 VBB27890.1 - 8.1e-07 28.8 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 KH domain EB PF01683.18 VBB27892.1 - 3.8e-118 385.7 299.5 7.5e-09 35.8 9.0 22.4 8 6 14 22 22 22 22 EB module TMEM100 PF16311.5 VBB27892.1 - 0.024 14.2 0.5 0.068 12.8 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 100 PWWP PF00855.17 VBB27893.1 - 5.7e-05 23.4 7.5 0.007 16.7 0.0 4.1 3 2 0 3 3 3 2 PWWP domain RTC4 PF14474.6 VBB27893.1 - 0.0066 16.6 0.1 3.6 7.8 0.1 3.3 3 0 0 3 3 3 2 RTC4-like domain Mito_carr PF00153.27 VBB27894.1 - 9.4e-58 192.2 5.1 3.5e-20 71.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 VBB27894.1 - 0.00022 20.5 1.7 0.00083 18.6 0.0 2.6 3 0 0 3 3 3 1 Gammaproteobacterial serine protease DnaJ PF00226.31 VBB27895.1 - 2.3e-27 94.9 2.0 3.5e-27 94.3 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain Yippee-Mis18 PF03226.14 VBB27896.1 - 1.2e-08 35.1 0.1 2.1e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LON_substr_bdg PF02190.16 VBB27896.1 - 7.6e-08 32.5 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-ribbon_3 PF13248.6 VBB27896.1 - 0.0025 17.1 1.6 0.23 10.9 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain RIG-I_C-RD PF11648.8 VBB27896.1 - 0.11 12.8 0.5 0.35 11.1 0.5 1.9 1 1 0 1 1 1 0 C-terminal domain of RIG-I ADD_ATRX PF17981.1 VBB27896.1 - 0.15 11.9 0.6 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-C2HC5 PF06221.13 VBB27896.1 - 0.27 11.2 1.8 1.9 8.5 0.4 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type NUDIX_2 PF13869.6 VBB27897.1 - 1.8e-77 259.2 0.0 2.2e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 VBB27897.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain RNA_pol_Rpb2_6 PF00562.28 VBB27898.1 - 2e-93 313.6 0.0 8e-93 311.6 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 VBB27898.1 - 7.7e-23 80.7 0.2 3.6e-22 78.6 0.2 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 VBB27898.1 - 7.8e-23 80.4 0.2 1.2e-21 76.7 0.2 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 VBB27898.1 - 5.8e-16 58.2 0.0 1.8e-14 53.5 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 VBB27898.1 - 3e-09 36.7 0.0 6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 VBB27898.1 - 9.1e-09 35.2 0.0 4.1e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 Sulfotransfer_2 PF03567.14 VBB27899.1 - 1.4e-23 84.2 2.3 2.3e-23 83.4 2.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 VBB27899.1 - 0.022 14.2 0.1 0.046 13.2 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase domain p25-alpha PF05517.12 VBB27900.1 - 0.064 13.4 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 p25-alpha DUF1492 PF07374.11 VBB27900.1 - 0.073 13.2 0.1 0.089 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) FAM91_N PF14647.6 VBB27901.1 - 1.8e-128 428.2 5.1 2.6e-128 427.7 5.1 1.2 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.6 VBB27901.1 - 2.3e-122 408.9 0.0 3.5e-122 408.4 0.0 1.3 1 0 0 1 1 1 1 FAM91 C-terminus BTB PF00651.31 VBB27901.1 - 4.6e-20 71.9 0.5 6.4e-10 39.3 0.1 2.8 2 0 0 2 2 2 2 BTB/POZ domain zf-H2C2_2 PF13465.6 VBB27901.1 - 2.4e-18 65.6 21.7 3e-07 30.5 0.5 4.8 4 0 0 4 4 4 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 VBB27901.1 - 2e-09 37.0 11.6 1.5e-05 24.6 2.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 VBB27901.1 - 8.1e-08 32.3 27.2 5.7e-06 26.5 0.7 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB27901.1 - 4.3e-07 30.2 22.6 0.0044 17.8 0.6 5.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 VBB27901.1 - 0.00097 19.4 10.2 0.53 10.6 10.2 3.5 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 VBB27901.1 - 0.025 14.9 20.7 0.014 15.7 7.8 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding KcnmB2_inactiv PF09303.10 VBB27901.1 - 0.18 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 KCNMB2, ball and chain domain zf-BED PF02892.15 VBB27901.1 - 0.63 10.1 10.9 3.1 7.9 1.9 3.2 2 1 1 3 3 3 0 BED zinc finger Elf1 PF05129.13 VBB27901.1 - 2.5 8.2 13.1 12 6.0 5.5 2.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 VBB27901.1 - 2.7 8.8 8.6 12 6.7 8.6 2.2 1 1 0 1 1 1 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 VBB27901.1 - 5 7.3 8.2 1.1 9.5 1.6 2.7 2 0 0 2 2 2 0 Zinc ribbon domain PRELI PF04707.14 VBB27902.1 - 6.8e-32 110.5 0.0 2.8e-17 63.0 0.0 2.1 1 1 1 2 2 2 2 PRELI-like family His_Phos_2 PF00328.22 VBB27903.1 - 9.2e-20 71.3 0.7 4.4e-13 49.3 0.2 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 VBB27903.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase MOLO1 PF17175.4 VBB27904.1 - 2.3e-07 30.9 0.2 4e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 Prominin PF05478.11 VBB27904.1 - 0.036 12.0 0.2 0.049 11.6 0.2 1.1 1 0 0 1 1 1 0 Prominin Tweety PF04906.13 VBB27904.1 - 0.1 11.2 0.9 0.18 10.4 0.9 1.3 1 0 0 1 1 1 0 Tweety NTP_transf_2 PF01909.23 VBB27905.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Peptidase_M1 PF01433.20 VBB27906.1 - 3.1e-86 288.5 0.9 5.4e-86 287.7 0.9 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 VBB27906.1 - 1.8e-63 215.0 0.0 5.2e-63 213.5 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 VBB27906.1 - 7.2e-53 179.5 0.3 1.3e-52 178.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 VBB27906.1 - 0.041 14.3 0.0 0.39 11.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold Clc-like PF07062.12 VBB27907.1 - 1.6e-46 158.4 12.6 2.4e-46 157.9 12.6 1.2 1 0 0 1 1 1 1 Clc-like PMP22_Claudin PF00822.20 VBB27907.1 - 1.1e-05 25.3 13.5 0.021 14.7 0.1 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 VBB27907.1 - 1.4e-05 25.0 10.3 3.1e-05 23.8 10.3 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 VBB27907.1 - 0.83 9.6 20.6 24 4.8 20.6 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like LapA_dom PF06305.11 VBB27907.1 - 0.89 9.4 9.1 0.14 12.0 4.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Serinc PF03348.15 VBB27907.1 - 3.4 6.5 14.8 11 4.8 0.2 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4491 PF14898.6 VBB27907.1 - 6 7.4 10.2 0.65 10.5 1.2 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4491) Clc-like PF07062.12 VBB27908.1 - 4.2e-23 81.9 5.7 8e-18 64.7 0.9 2.0 1 1 1 2 2 2 2 Clc-like PMP22_Claudin PF00822.20 VBB27908.1 - 0.00014 21.8 0.3 0.00015 21.7 0.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 VBB27908.1 - 0.014 15.6 0.8 0.017 15.4 0.8 1.1 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Pkinase PF00069.25 VBB27910.1 - 1.4e-16 60.6 0.0 2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27910.1 - 4.7e-10 39.2 0.1 6.8e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LBP_BPI_CETP_C PF02886.17 VBB27911.1 - 9.6e-15 54.7 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Tetraspanin PF00335.20 VBB27912.1 - 7.5e-41 140.3 14.3 8.8e-41 140.1 14.3 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 VBB27912.1 - 0.0074 16.4 5.6 0.0074 16.4 5.6 1.9 2 1 0 2 2 2 1 CD20-like family DUF817 PF05675.12 VBB27912.1 - 0.0083 15.8 0.3 0.0083 15.8 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF817) DUF3566 PF12089.8 VBB27912.1 - 0.62 10.4 7.1 0.45 10.9 0.6 2.8 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Filamin PF00630.19 VBB27913.1 - 5.9e-28 97.7 0.2 3e-18 66.5 0.1 2.1 2 0 0 2 2 2 2 Filamin/ABP280 repeat Y_Y_Y PF07495.13 VBB27913.1 - 0.003 17.5 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 Y_Y_Y domain Big_3_5 PF16640.5 VBB27913.1 - 0.077 13.2 0.0 0.89 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF4364 PF14277.6 VBB27913.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Filamin PF00630.19 VBB27914.1 - 1.7e-116 382.1 16.5 1.4e-11 45.1 0.2 15.6 15 0 0 15 15 15 14 Filamin/ABP280 repeat Y_Y_Y PF07495.13 VBB27914.1 - 9.7e-07 28.7 3.9 12 5.9 0.0 7.3 7 0 0 7 7 7 2 Y_Y_Y domain DUF5060 PF16586.5 VBB27914.1 - 5.3e-06 26.7 0.0 19 5.7 0.0 7.9 10 0 0 10 10 10 1 Domain of unknown function (DUF5060) PPC PF04151.15 VBB27914.1 - 0.0018 19.3 0.1 0.48 11.5 0.0 3.9 4 0 0 4 4 4 1 Bacterial pre-peptidase C-terminal domain DUF3244 PF11589.8 VBB27914.1 - 0.069 13.2 10.6 4.4 7.4 0.0 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3244) PapC_N PF13954.6 VBB27914.1 - 0.42 10.6 1.5 36 4.3 0.0 4.5 6 0 0 6 6 6 0 PapC N-terminal domain EMP24_GP25L PF01105.24 VBB27914.1 - 5.2 7.0 12.2 9 6.2 0.0 5.7 7 2 1 8 8 8 0 emp24/gp25L/p24 family/GOLD PDZ_6 PF17820.1 VBB27916.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB27916.1 - 1.7e-08 34.7 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 VBB27916.1 - 1.8e-06 29.0 0.2 1.8e-06 29.0 0.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_2 PF13180.6 VBB27916.1 - 0.0096 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Ripply PF14998.6 VBB27916.1 - 0.12 13.0 2.3 0.46 11.1 0.1 2.5 2 0 0 2 2 2 0 Transcription Regulator Zip PF02535.22 VBB27917.1 - 2.1e-49 168.6 4.8 2.7e-49 168.2 4.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2120 PF09893.9 VBB27917.1 - 0.079 13.1 0.6 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1129 PF06570.11 VBB27917.1 - 0.14 11.6 9.8 2.4 7.6 2.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Flavi_M PF01004.19 VBB27917.1 - 0.27 11.0 2.2 1.4 8.7 0.1 2.7 2 1 0 2 2 2 0 Flavivirus envelope glycoprotein M E1-E2_ATPase PF00122.20 VBB27917.1 - 4.4 6.8 8.6 2.6 7.5 0.0 3.1 3 0 0 3 3 3 0 E1-E2 ATPase RabGAP-TBC PF00566.18 VBB27918.1 - 2.4e-48 164.6 0.3 5.3e-48 163.5 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 VBB27918.1 - 1e-05 26.0 0.0 3.7e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 PH domain MipZ PF09140.11 VBB27918.1 - 0.051 12.8 0.3 0.14 11.4 0.3 1.7 1 0 0 1 1 1 0 ATPase MipZ DUF1657 PF07870.11 VBB27918.1 - 0.1 12.5 0.1 14 5.6 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DUF883 PF05957.13 VBB27918.1 - 3.4 8.3 5.0 1.4 9.5 1.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Homeodomain PF00046.29 VBB27919.1 - 2.8e-24 84.7 6.6 4.9e-24 83.9 6.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27919.1 - 0.048 13.6 0.1 0.048 13.6 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain CHORD PF04968.12 VBB27920.1 - 5.9e-50 167.8 24.3 7.2e-25 87.5 9.1 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 VBB27920.1 - 0.0019 19.2 0.0 0.0051 17.8 0.0 1.7 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.6 VBB27920.1 - 0.019 14.6 2.9 0.83 9.3 0.1 2.9 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding BTK PF00779.19 VBB27920.1 - 1.1 9.2 18.4 2.1 8.2 4.8 4.0 4 1 0 4 4 4 0 BTK motif Utp13 PF08625.11 VBB27921.1 - 7.6e-38 129.6 1.8 1.3e-37 128.8 1.8 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 VBB27921.1 - 1.9e-31 107.6 28.8 8.6e-05 23.2 0.1 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27921.1 - 1.7e-07 31.4 7.0 0.72 10.2 0.2 8.1 4 3 4 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 VBB27921.1 - 8.9e-07 28.0 6.1 0.13 11.0 0.2 5.1 1 1 4 5 5 5 3 Nup133 N terminal like NUP214 PF16755.5 VBB27921.1 - 0.0019 17.5 2.1 0.044 13.0 0.2 3.3 2 1 1 4 4 4 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 UTP15_C PF09384.10 VBB27921.1 - 0.0047 16.6 0.2 0.0086 15.8 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal VP9 PF09625.10 VBB27921.1 - 0.086 13.0 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 VP9 protein KH_1 PF00013.29 VBB27922.1 - 0.041 13.7 0.6 0.084 12.7 0.6 1.5 1 0 0 1 1 1 0 KH domain DM PF00751.18 VBB27923.1 - 1.2e-16 60.3 7.5 1.8e-16 59.7 7.5 1.3 1 0 0 1 1 1 1 DM DNA binding domain Mucin PF01456.17 VBB27923.1 - 0.00025 21.1 17.7 0.00036 20.6 17.7 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1178 PF06676.11 VBB27923.1 - 0.004 17.5 0.9 0.0061 17.0 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) LPP20 PF02169.16 VBB27923.1 - 0.0097 16.2 4.3 0.015 15.7 4.3 1.3 1 0 0 1 1 1 1 LPP20 lipoprotein DUF3439 PF11921.8 VBB27923.1 - 0.067 13.2 15.6 0.027 14.4 12.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) AJAP1_PANP_C PF15298.6 VBB27923.1 - 0.31 11.2 12.9 0.46 10.7 12.9 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3347 PF11827.8 VBB27923.1 - 0.37 11.0 2.6 0.54 10.4 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) FAP PF07174.11 VBB27923.1 - 0.5 9.8 8.9 0.7 9.3 8.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MGC-24 PF05283.11 VBB27923.1 - 0.51 10.8 10.5 0.76 10.2 10.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 VBB27923.1 - 0.76 7.8 11.1 0.94 7.5 11.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 VBB27923.1 - 4.8 5.3 21.9 6.4 4.8 21.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MOR2-PAG1_C PF14225.6 VBB27924.1 - 9.9e-34 117.3 5.6 4.5e-33 115.2 5.6 2.3 1 1 0 1 1 1 1 Cell morphogenesis C-terminal Sel1 PF08238.12 VBB27924.1 - 0.18 12.5 0.0 0.42 11.4 0.0 1.6 1 0 0 1 1 1 0 Sel1 repeat T-box PF00907.22 VBB27925.1 - 1.9e-06 28.3 0.1 4.3e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 T-box ADIP PF11559.8 VBB27926.1 - 0.0066 16.5 1.1 0.0066 16.5 1.1 7.5 4 2 3 7 7 7 2 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 VBB27926.1 - 0.009 16.5 17.5 0.009 16.5 17.5 6.0 2 1 3 5 5 5 1 Fez1 DUF1192 PF06698.11 VBB27926.1 - 3.4 7.8 9.7 8.6 6.5 0.3 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) UPF0767 PF15990.5 VBB27926.1 - 4.7 7.4 5.7 3 8.0 0.0 3.8 3 0 0 3 3 3 0 UPF0767 family Maf1 PF09174.10 VBB27927.1 - 1.5e-34 119.7 2.5 4.1e-23 82.4 0.1 2.2 2 0 0 2 2 2 2 Maf1 regulator DEAD PF00270.29 VBB27928.1 - 8.3e-45 152.7 0.1 1.3e-44 152.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Archease PF01951.16 VBB27928.1 - 5.4e-33 114.2 0.0 1.2e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Helicase_C PF00271.31 VBB27928.1 - 1.7e-18 67.0 0.0 1.8e-17 63.7 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB27928.1 - 1.9e-07 31.3 0.0 4.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 VBB27928.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain Ndc80_HEC PF03801.13 VBB27928.1 - 0.034 13.8 0.1 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 HEC/Ndc80p family DUF2075 PF09848.9 VBB27928.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 VBB27928.1 - 0.38 11.0 1.5 1.4 9.2 1.5 2.0 1 1 0 1 1 1 0 AAA domain DSPc PF00782.20 VBB27929.1 - 1.4e-33 115.5 0.0 1.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB27929.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB27930.1 - 1.8e-69 231.7 0.0 1.5e-34 118.6 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB27930.1 - 2e-09 37.4 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 VBB27930.1 - 6.7e-05 23.1 0.1 0.36 11.2 0.0 2.4 2 0 0 2 2 2 2 Rit1 DUSP-like domain DUF442 PF04273.13 VBB27930.1 - 0.0019 18.3 0.1 2.5 8.2 0.1 2.4 2 0 0 2 2 2 2 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 VBB27930.1 - 0.0036 17.3 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Myotub-related PF06602.14 VBB27930.1 - 0.041 12.8 0.1 6.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain PDEase_I PF00233.19 VBB27931.1 - 9.1e-52 176.1 7.3 2.3e-35 122.4 0.0 2.3 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 VBB27931.1 - 7e-22 77.0 1.9 1.2e-21 76.3 0.1 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal Ins145_P3_rec PF08709.11 VBB27932.1 - 1.2e-53 181.5 0.1 1.5e-53 181.2 0.1 1.1 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 VBB27932.1 - 1.8e-05 24.7 0.1 0.00014 21.7 0.1 2.1 1 1 1 2 2 2 2 MIR domain DUF2336 PF10098.9 VBB27933.1 - 0.00041 19.9 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) SAP PF02037.27 VBB27933.1 - 0.022 14.5 0.0 0.072 12.9 0.0 2.0 1 0 0 1 1 1 0 SAP domain BTB PF00651.31 VBB27933.1 - 0.037 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain LEM PF03020.15 VBB27933.1 - 0.11 12.1 2.4 0.27 10.8 0.0 2.9 3 0 0 3 3 3 0 LEM domain Pardaxin PF07425.11 VBB27933.1 - 0.17 11.5 1.7 0.53 9.9 1.7 1.8 1 0 0 1 1 1 0 Pardaxin RhoGEF PF00621.20 VBB27934.1 - 2.7e-26 92.9 11.0 3.6e-15 56.7 0.7 3.5 3 1 1 4 4 4 2 RhoGEF domain LRR_8 PF13855.6 VBB27935.1 - 9.9e-17 60.5 27.2 9.8e-06 25.3 2.8 5.4 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 VBB27935.1 - 2.2e-16 59.7 32.4 7.1e-05 23.1 2.7 5.7 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 VBB27935.1 - 0.022 15.4 0.0 0.069 13.8 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain Apolipoprotein PF01442.18 VBB27935.1 - 0.046 13.6 4.8 0.1 12.5 4.8 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ig PF00047.25 VBB27935.1 - 0.056 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain FAM184 PF15665.5 VBB27935.1 - 0.069 12.9 7.8 0.13 12.0 7.8 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FGAR-AT_N PF18076.1 VBB27935.1 - 0.083 12.9 0.7 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal I-set PF07679.16 VBB27935.1 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin I-set domain UBA_2 PF08587.11 VBB27935.1 - 0.13 12.4 0.8 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DUF3150 PF11348.8 VBB27935.1 - 0.15 11.2 1.7 1.4 8.1 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3150) Exonuc_VII_L PF02601.15 VBB27935.1 - 1 8.9 10.3 1.6 8.2 10.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LRR_9 PF14580.6 VBB27935.1 - 1.3 8.5 7.5 0.19 11.2 0.2 2.8 2 1 1 3 3 3 0 Leucine-rich repeat FAP206 PF12018.8 VBB27935.1 - 4.1 6.8 9.4 3.1 7.2 7.4 1.7 1 1 1 2 2 2 0 Domain of unknown function LRR_1 PF00560.33 VBB27935.1 - 5.6 7.9 42.3 16 6.5 1.8 10.0 7 3 2 9 9 8 0 Leucine Rich Repeat Ribosomal_S18 PF01084.20 VBB27936.1 - 2.9e-15 56.2 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 Homeodomain PF00046.29 VBB27937.1 - 2.6e-23 81.6 6.5 4.7e-23 80.8 6.5 1.4 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 VBB27937.1 - 1.1e-11 43.8 0.6 1.9e-11 43.0 0.6 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.11 VBB27937.1 - 0.00016 21.5 0.7 0.00047 20.0 0.7 1.9 1 1 0 1 1 1 1 Homeobox KN domain QLQ PF08880.11 VBB27937.1 - 0.0018 18.0 0.3 0.004 16.9 0.3 1.6 1 0 0 1 1 1 1 QLQ CENP-B_N PF04218.13 VBB27937.1 - 0.0054 16.3 0.8 0.01 15.5 0.8 1.6 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain CENP-F_N PF10481.9 VBB27937.1 - 0.01 15.5 1.3 0.011 15.4 1.3 1.1 1 0 0 1 1 1 1 Cenp-F N-terminal domain MerR_1 PF13411.6 VBB27937.1 - 0.073 13.2 0.4 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein HTH_26 PF13443.6 VBB27937.1 - 0.099 13.1 0.1 1.6 9.3 0.0 2.1 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain Pkinase PF00069.25 VBB27938.1 - 2.8e-77 259.7 0.0 1.7e-37 129.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27938.1 - 1.7e-35 122.6 0.4 1.4e-22 80.2 0.0 3.1 4 0 0 4 4 4 2 Protein tyrosine kinase I-set PF07679.16 VBB27938.1 - 6.7e-18 64.5 0.0 2e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB27938.1 - 6e-10 39.6 0.0 1.8e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 VBB27938.1 - 6.7e-09 36.0 0.0 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Kinase-like PF14531.6 VBB27938.1 - 5e-08 32.6 0.0 3.6e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like ig PF00047.25 VBB27938.1 - 1.7e-06 28.1 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Kdo PF06293.14 VBB27938.1 - 5.8e-06 25.8 2.0 0.002 17.5 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Ig_2 PF13895.6 VBB27938.1 - 0.00021 21.6 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB27938.1 - 0.0086 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 C17orf99 Ig domain RIO1 PF01163.22 VBB27938.1 - 0.14 11.8 7.8 0.14 11.8 0.1 2.8 3 0 0 3 3 3 0 RIO1 family PdaC PF13739.6 VBB27938.1 - 0.47 11.5 5.0 0.34 11.9 2.5 2.1 2 0 0 2 2 2 0 Deacetylase PdaC I-set PF07679.16 VBB27939.1 - 0 2204.8 99.3 5.5e-23 80.8 0.0 41.6 41 1 0 41 41 41 41 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB27939.1 - 0 1462.6 43.7 1.1e-15 58.0 0.0 41.2 41 0 0 41 41 41 40 Immunoglobulin domain ig PF00047.25 VBB27939.1 - 2.8e-251 812.6 48.7 2.6e-11 43.5 0.0 39.4 39 0 0 39 39 39 37 Immunoglobulin domain Ig_2 PF13895.6 VBB27939.1 - 2.3e-245 793.7 27.5 2.2e-10 40.7 0.0 40.2 40 0 0 40 40 40 35 Immunoglobulin domain V-set PF07686.17 VBB27939.1 - 1.8e-115 378.8 79.7 0.00032 20.9 0.0 48.1 40 18 0 40 40 38 26 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB27939.1 - 1.5e-58 194.8 34.2 0.013 15.6 0.1 33.0 35 1 1 36 36 35 12 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 VBB27939.1 - 1.6e-36 124.2 0.0 0.23 11.5 0.0 23.9 26 2 0 26 26 24 6 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 VBB27939.1 - 5e-35 120.0 27.5 0.038 14.2 0.1 23.0 27 0 0 27 27 24 7 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 VBB27939.1 - 5.3e-35 119.3 32.3 0.074 13.1 0.0 23.8 26 0 0 26 26 24 7 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 VBB27939.1 - 2e-21 76.0 59.5 1.1 9.6 0.1 28.3 31 0 0 31 31 30 4 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 VBB27939.1 - 4.2e-19 67.8 2.2 0.035 13.7 0.0 14.8 19 0 0 19 19 16 1 Immunoglobulin domain C1-set PF07654.15 VBB27939.1 - 2.8e-16 59.7 57.2 1.8 9.0 0.0 26.5 31 0 0 31 31 29 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 VBB27939.1 - 3e-13 49.6 4.1 6.8 6.8 0.0 15.5 18 0 0 18 18 17 1 C17orf99 Ig domain Herpes_gE PF02480.16 VBB27939.1 - 8.2e-10 38.0 19.2 0.28 9.9 0.4 12.8 10 3 5 15 15 15 2 Alphaherpesvirus glycoprotein E fn3 PF00041.21 VBB27939.1 - 1.5e-08 34.9 0.0 1.2e-07 31.9 0.0 2.8 1 0 0 1 1 1 1 Fibronectin type III domain V-set_CD47 PF08204.11 VBB27939.1 - 2.4e-05 24.3 48.3 0.29 11.1 0.4 17.5 20 1 1 21 21 20 2 CD47 immunoglobulin-like domain PKD_3 PF16820.5 VBB27939.1 - 0.00063 19.4 11.9 23 4.8 0.0 10.1 11 0 0 11 11 8 0 PKD-like domain bMG6 PF17962.1 VBB27939.1 - 0.0031 17.7 15.0 5.4 7.2 0.3 9.1 10 0 0 10 10 7 2 Bacterial macroglobulin domain 6 DUF4198 PF10670.9 VBB27939.1 - 0.0037 17.7 17.4 45 4.3 0.1 11.6 13 3 2 16 16 14 0 Domain of unknown function (DUF4198) ACAS_N PF16177.5 VBB27939.1 - 0.0065 16.4 17.9 22 5.0 0.0 13.3 18 0 0 18 18 16 0 Acetyl-coenzyme A synthetase N-terminus 53-BP1_Tudor PF09038.10 VBB27939.1 - 0.032 14.2 3.3 0.3 11.0 0.1 4.2 4 1 1 5 5 3 0 Tumour suppressor p53-binding protein-1 Tudor DUF2914 PF11141.8 VBB27939.1 - 0.088 12.6 21.6 1.8 8.4 0.1 10.0 13 0 0 13 13 12 0 Protein of unknown function (DUF2914) HOIP-UBA PF16678.5 VBB27939.1 - 0.23 11.4 2.9 8.2 6.4 0.1 3.2 3 0 0 3 3 2 0 HOIP UBA domain pair MOLO1 PF17175.4 VBB27940.1 - 2.9e-27 95.1 0.5 4.7e-27 94.5 0.5 1.3 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 VBB27940.1 - 4.9e-11 42.9 0.4 3.7e-09 36.8 0.4 2.1 1 1 0 1 1 1 1 TPM domain TMEM52 PF14979.6 VBB27940.1 - 0.94 9.4 7.4 2 8.3 7.4 1.5 1 0 0 1 1 1 0 Transmembrane 52 HEV_ORF1 PF02444.16 VBB27940.1 - 8 7.1 13.8 0.83 10.2 8.6 2.0 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) Flu_M1_C PF08289.11 VBB27941.1 - 0.063 13.5 0.7 0.091 13.0 0.7 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF3246 PF11596.8 VBB27942.1 - 0.015 14.8 1.0 0.016 14.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RGS_DHEX PF18148.1 VBB27943.1 - 7.4e-49 164.0 2.3 2e-48 162.6 2.3 1.8 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 VBB27943.1 - 5.1e-28 97.7 1.5 5.1e-28 97.7 1.5 2.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 VBB27943.1 - 1.5e-13 50.6 0.0 4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 VBB27943.1 - 4.1e-11 42.7 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 GGL domain TetR_C_37 PF18665.1 VBB27943.1 - 0.042 14.5 0.5 3.2 8.4 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rhabdo_NV PF02484.15 VBB27943.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein CDI PF02234.19 VBB27943.1 - 2 8.7 6.2 0.37 11.0 1.8 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor LRR_4 PF12799.7 VBB27944.1 - 0.89 10.1 30.0 3.4 8.2 2.8 6.8 5 2 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB27944.1 - 6.4 7.7 17.9 5.7 7.9 0.5 6.8 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 VBB27944.1 - 6.7 7.0 31.9 1 9.6 0.1 8.9 11 0 0 11 11 11 0 Leucine Rich repeat MOLO1 PF17175.4 VBB27945.1 - 1.1e-28 99.7 0.7 1.4e-28 99.4 0.7 1.1 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 SPRY PF00622.28 VBB27946.1 - 2.4e-13 50.3 0.0 4.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.21 VBB27946.1 - 6.7e-07 29.6 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF1041 PF06292.17 VBB27946.1 - 0.023 15.1 1.0 0.061 13.7 0.4 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) DUF1664 PF07889.12 VBB27946.1 - 0.15 12.1 3.1 4.3 7.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF445 PF04286.12 VBB27946.1 - 0.15 11.8 2.3 0.21 11.3 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1938 PF09153.10 VBB27946.1 - 0.25 11.4 0.6 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) DUF4279 PF14106.6 VBB27946.1 - 0.44 10.8 3.9 8.3 6.7 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) Pkinase PF00069.25 VBB27947.1 - 6.9e-51 173.1 0.0 8.8e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27947.1 - 4.2e-20 72.1 0.0 5.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB27947.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB27947.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-BED PF02892.15 VBB27948.1 - 2.6e-10 40.2 9.5 5.6e-05 23.1 0.4 2.5 2 0 0 2 2 2 2 BED zinc finger zf-H2C2_5 PF13909.6 VBB27948.1 - 0.02 14.7 18.5 0.67 9.8 8.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain OrsD PF12013.8 VBB27948.1 - 0.042 14.3 0.6 0.042 14.3 0.6 3.3 4 0 0 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 VBB27948.1 - 0.14 13.1 14.3 2.1 9.4 5.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Innexin PF00876.18 VBB27949.1 - 1.2e-95 320.8 14.9 3.5e-50 171.3 8.8 2.0 1 1 1 2 2 2 2 Innexin Aminotran_1_2 PF00155.21 VBB27951.1 - 3.5e-49 167.9 0.0 4.6e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 VBB27951.1 - 0.00019 20.5 0.0 0.0005 19.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 VBB27951.1 - 0.02 14.2 0.1 0.11 11.8 0.1 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C4 PF00105.18 VBB27952.1 - 9.5e-26 90.1 13.5 2.3e-25 88.8 13.5 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB27952.1 - 7.5e-12 45.3 0.2 6e-11 42.3 0.2 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Forkhead PF00250.18 VBB27953.1 - 5e-09 36.3 1.9 7.8e-06 26.1 0.1 3.2 2 1 1 3 3 3 2 Forkhead domain FHA PF00498.26 VBB27953.1 - 2.5e-06 27.7 1.4 1.3e-05 25.4 0.1 2.9 3 0 0 3 3 3 1 FHA domain Sod_Ni PF09055.11 VBB27954.1 - 0.066 13.8 2.9 0.12 12.9 1.9 1.8 1 1 2 3 3 3 0 Nickel-containing superoxide dismutase Ubiq_cyt_C_chap PF03981.12 VBB27955.1 - 5.8e-25 88.0 2.9 7.7e-25 87.6 0.6 2.0 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone 7tm_1 PF00001.21 VBB27956.1 - 3.3e-19 69.2 20.7 4.6e-19 68.8 20.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4059 PF13268.6 VBB27956.1 - 1.6 9.2 6.4 0.56 10.7 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4059) Pkinase PF00069.25 VBB27957.1 - 1.3e-42 146.0 0.0 3.5e-42 144.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27957.1 - 8e-24 84.3 0.0 1.7e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB27957.1 - 9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB27957.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB27957.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 VBB27957.1 - 0.0066 15.4 0.1 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB27957.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GRP PF07172.11 VBB27958.1 - 2.1e-05 25.1 0.0 3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycine rich protein family ARS2 PF04959.13 VBB27958.1 - 0.18 12.2 0.7 0.21 12.0 0.7 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 DUF2975 PF11188.8 VBB27960.1 - 0.018 14.9 3.0 0.026 14.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4131 PF13567.6 VBB27960.1 - 0.13 11.9 1.8 0.15 11.7 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HbrB PF08539.11 VBB27961.1 - 0.038 14.0 1.0 0.045 13.8 1.0 1.1 1 0 0 1 1 1 0 HbrB-like P22_portal PF16510.5 VBB27961.1 - 3.6 6.1 10.1 3.4 6.1 10.1 1.0 1 0 0 1 1 1 0 Phage P22-like portal protein GTP_EFTU PF00009.27 VBB27963.1 - 7.4e-50 169.2 0.0 1.1e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 VBB27963.1 - 3e-16 59.2 0.0 7.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 VBB27963.1 - 6e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 VBB27963.1 - 0.0025 17.4 0.2 0.0051 16.4 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B EFG_IV PF03764.18 VBB27963.1 - 0.0086 15.8 0.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 VBB27963.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Endosulfine PF04667.17 VBB27965.1 - 5.6e-14 52.0 0.8 1e-13 51.2 0.8 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Anillin_N PF16018.5 VBB27965.1 - 0.09 13.4 1.4 0.21 12.2 0.2 2.0 2 0 0 2 2 2 0 Anillin N-terminus Rota_NSP4 PF01452.16 VBB27966.1 - 0.054 13.2 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein GRDP-like PF07173.12 VBB27966.1 - 0.088 13.5 0.0 0.1 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like MADF_DNA_bdg PF10545.9 VBB27966.1 - 0.092 13.1 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TUDOR PF00567.24 VBB27967.1 - 3.8e-13 49.5 0.0 6.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain PrpR_N PF06506.11 VBB27967.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator KIP1 PF07765.12 VBB27968.1 - 0.034 14.3 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 KIP1-like protein zf-C4H2 PF10146.9 VBB27968.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein MFS_1 PF07690.16 VBB27969.1 - 3.8e-30 105.0 38.7 3.9e-30 105.0 34.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 VBB27969.1 - 2.4e-08 33.3 29.4 0.001 18.0 15.2 4.0 1 1 3 4 4 4 4 MFS_1 like family Nrap_D4 PF17405.2 VBB27970.1 - 9e-33 113.4 0.0 1.6e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 VBB27970.1 - 1.9e-25 89.8 0.0 4.1e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 VBB27970.1 - 1.6e-24 86.7 0.0 3.3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 VBB27970.1 - 9e-24 84.1 0.0 1.9e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 VBB27970.1 - 1.1e-17 64.5 0.0 2.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 VBB27970.1 - 3.3e-10 39.9 2.8 7e-10 38.9 2.8 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain DUF4619 PF15398.6 VBB27970.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Snurportin1 PF11538.8 VBB27971.1 - 6.4e-16 58.3 8.2 1.1e-15 57.5 8.2 1.4 1 0 0 1 1 1 1 Snurportin1 mRNA_cap_enzyme PF01331.19 VBB27971.1 - 0.001 18.9 0.4 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain DCAF17 PF15802.5 VBB27972.1 - 2.2e-17 63.0 0.1 4e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 DUF3848 PF12959.7 VBB27972.1 - 0.0088 16.1 0.5 0.026 14.6 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) PAPS_reduct PF01507.19 VBB27973.1 - 3.5e-28 98.8 0.0 1.5e-25 90.2 0.0 2.7 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 VBB27973.1 - 3.2e-25 88.5 0.0 8.5e-25 87.1 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain RWD PF05773.22 VBB27974.1 - 9.2e-20 71.1 0.1 2.9e-19 69.5 0.1 1.9 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 VBB27974.1 - 1.9e-11 44.0 0.7 1.9e-11 44.0 0.7 4.2 3 1 1 4 4 4 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 VBB27974.1 - 1.9e-05 24.9 5.6 1.9e-05 24.9 5.6 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 VBB27974.1 - 9.4e-05 22.3 9.5 9.4e-05 22.3 9.5 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 VBB27974.1 - 0.00025 20.8 6.5 0.00025 20.8 6.5 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB27974.1 - 0.00051 20.0 6.5 0.00051 20.0 6.5 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB27974.1 - 0.00068 19.4 4.5 0.00068 19.4 4.5 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 VBB27974.1 - 0.0012 18.6 9.3 0.0012 18.6 9.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 VBB27974.1 - 0.0027 17.6 6.4 0.0027 17.6 6.4 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB27974.1 - 0.0032 17.6 1.2 0.0032 17.6 1.2 4.1 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING HTH_20 PF12840.7 VBB27974.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Frankia_peptide PF14407.6 VBB27974.1 - 0.14 12.2 0.5 0.47 10.5 0.1 2.1 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Zn_Tnp_IS91 PF14319.6 VBB27974.1 - 0.19 11.8 0.2 0.19 11.8 0.2 3.5 3 0 0 3 3 3 0 Transposase zinc-binding domain zf-piccolo PF05715.13 VBB27974.1 - 0.23 11.7 6.5 13 6.0 2.9 3.0 2 0 0 2 2 2 0 Piccolo Zn-finger DNA_ligase_ZBD PF03119.16 VBB27974.1 - 1.6 8.8 5.3 27 4.9 0.4 3.1 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Prok-RING_4 PF14447.6 VBB27974.1 - 1.6 8.6 23.0 0.1 12.5 5.5 3.9 3 2 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_14 PF17978.1 VBB27974.1 - 5.6 7.5 13.0 0.051 14.0 3.9 2.3 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain DAN PF03045.15 VBB27975.1 - 2.1e-26 92.2 6.9 2.9e-26 91.7 6.9 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 VBB27975.1 - 0.021 15.1 4.3 0.034 14.4 4.3 1.3 1 0 0 1 1 1 0 Cystine-knot domain Clathrin_bdg PF15045.6 VBB27976.1 - 0.0049 16.8 0.1 0.02 14.9 0.1 2.1 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Metallophos PF00149.28 VBB27977.1 - 5.3e-32 112.0 0.1 1.1e-31 110.9 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 VBB27977.1 - 5.6e-28 98.0 1.7 4.5e-25 88.5 0.1 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB27977.1 - 2.7e-16 59.6 0.0 5.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.14 VBB27977.1 - 0.046 12.0 9.5 0.065 11.5 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BORG_CEP PF14957.6 VBB27977.1 - 0.098 13.8 6.3 0.18 13.0 6.3 1.4 1 0 0 1 1 1 0 Cdc42 effector APH PF01636.23 VBB27977.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PTPRCAP PF15713.5 VBB27977.1 - 0.3 11.4 16.6 0.52 10.6 16.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 VBB27977.1 - 0.35 10.6 18.6 0.64 9.8 18.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 VBB27977.1 - 0.44 10.5 7.1 0.8 9.7 7.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Borrelia_P83 PF05262.11 VBB27977.1 - 0.49 8.8 11.7 0.7 8.3 11.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Vfa1 PF08432.10 VBB27977.1 - 0.72 10.2 18.7 1.3 9.4 18.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 VBB27977.1 - 1.4 7.9 7.0 2.8 6.8 7.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 VBB27977.1 - 2.1 7.0 11.5 3.3 6.4 11.5 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 VBB27977.1 - 2.2 8.4 4.7 3.6 7.7 4.7 1.3 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.16 VBB27977.1 - 2.9 7.4 12.4 5.1 6.6 12.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 VBB27977.1 - 3.6 6.3 12.3 5.4 5.7 12.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 VBB27977.1 - 4.1 7.8 11.1 8.7 6.8 11.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 V_ATPase_I PF01496.19 VBB27977.1 - 5.7 4.7 12.1 11 3.8 12.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RP-C_C PF11800.8 VBB27977.1 - 6.4 6.8 15.1 11 6.1 15.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Zip PF02535.22 VBB27977.1 - 8 5.6 7.6 14 4.7 7.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter EGF_3 PF12947.7 VBB27980.1 - 1.2e-47 159.8 189.9 9.6e-10 38.5 9.0 12.6 12 0 0 12 12 12 10 EGF domain Ldl_recept_b PF00058.17 VBB27980.1 - 1.6e-25 89.3 5.7 2.3e-06 27.9 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B EGF PF00008.27 VBB27980.1 - 2.8e-18 65.9 168.8 0.00052 20.3 6.1 12.8 12 0 0 12 12 12 9 EGF-like domain EGF_MSP1_1 PF12946.7 VBB27980.1 - 2.3e-15 56.4 152.7 0.00039 20.4 7.5 11.5 11 0 0 11 11 10 10 MSP1 EGF domain 1 EGF_CA PF07645.15 VBB27980.1 - 2.1e-10 40.6 8.0 2.1e-10 40.6 8.0 12.4 11 1 1 12 12 10 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 VBB27980.1 - 1.2e-06 28.7 4.9 1.2e-06 28.7 4.9 12.4 11 1 1 12 12 11 3 Coagulation Factor Xa inhibitory site hEGF PF12661.7 VBB27980.1 - 6.6e-05 23.4 10.8 0.0011 19.5 1.8 15.5 15 4 2 17 17 13 4 Human growth factor-like EGF SGL PF08450.12 VBB27980.1 - 0.00025 20.7 0.4 0.07 12.7 0.4 3.4 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 VBB27980.1 - 0.002 17.5 0.4 0.012 14.9 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5050) cEGF PF12662.7 VBB27980.1 - 0.0059 16.5 13.6 0.0089 15.9 5.7 11.7 13 0 0 13 13 12 5 Complement Clr-like EGF-like Arylesterase PF01731.20 VBB27980.1 - 0.0068 16.6 0.0 3.4 8.0 0.0 3.5 3 1 1 4 4 3 1 Arylesterase NHL PF01436.21 VBB27980.1 - 0.04 14.0 0.8 12 6.1 0.0 4.3 4 0 0 4 4 4 0 NHL repeat TSP_1 PF00090.19 VBB27982.1 - 0.19 12.0 2.0 19 5.6 0.6 2.5 2 0 0 2 2 2 0 Thrombospondin type 1 domain Flt3_lig PF02947.14 VBB27983.1 - 0.00092 19.4 0.2 0.27 11.4 0.0 2.2 2 0 0 2 2 2 2 flt3 ligand STAR_dimer PF16544.5 VBB27983.1 - 0.089 12.4 1.1 0.22 11.1 1.1 1.7 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein RNHCP PF12647.7 VBB27984.1 - 6.9 6.7 7.9 7.7 6.6 0.3 3.4 3 1 1 4 4 4 0 RNHCP domain C1_2 PF03107.16 VBB27985.1 - 2 8.8 14.6 6.8 7.1 0.7 3.6 3 0 0 3 3 3 0 C1 domain Got1 PF04178.12 VBB27986.1 - 4.4e-20 72.2 7.5 7.4e-20 71.5 7.5 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Oxidored_q4 PF00507.19 VBB27986.1 - 0.019 15.1 1.6 0.037 14.2 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 EF-hand_1 PF00036.32 VBB27987.1 - 1.5e-40 133.7 12.3 4.5e-10 38.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB27987.1 - 3e-34 117.3 5.5 7.2e-18 64.8 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB27987.1 - 2.3e-30 104.2 13.2 3.6e-13 49.1 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 VBB27987.1 - 8.9e-30 100.1 6.5 4.2e-09 35.6 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 VBB27987.1 - 5.9e-22 76.1 7.2 1.2e-05 24.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 VBB27987.1 - 2.7e-12 46.8 0.2 4.2e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 VBB27987.1 - 4.8e-09 36.1 1.6 0.003 17.5 0.1 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 VBB27987.1 - 2.5e-05 24.2 0.0 0.83 9.7 0.0 3.2 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 VBB27987.1 - 0.00017 21.9 0.2 0.15 12.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 VBB27987.1 - 0.00036 21.4 0.1 0.0074 17.1 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 VBB27987.1 - 0.0012 18.9 1.2 0.0023 18.0 0.5 1.9 1 1 0 1 1 1 1 Ca2+ insensitive EF hand Caleosin PF05042.13 VBB27987.1 - 0.01 15.8 1.4 11 5.9 0.0 3.6 1 1 3 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 VBB27987.1 - 0.027 14.6 1.8 1.3 9.2 0.3 2.9 1 1 1 2 2 2 0 Dockerin type I domain DUF4891 PF16232.5 VBB27987.1 - 0.035 14.6 0.0 5 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4891) DUF4497 PF14924.6 VBB27987.1 - 0.035 14.6 0.0 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) p25-alpha PF05517.12 VBB27987.1 - 0.067 13.4 0.4 14 5.8 0.0 2.8 2 1 1 3 3 3 0 p25-alpha PMBR PF09373.10 VBB27987.1 - 0.084 13.1 0.9 80 3.7 0.0 4.2 6 0 0 6 6 5 0 Pseudomurein-binding repeat DUF4704 PF15787.5 VBB27989.1 - 3.1e-91 305.5 0.3 3.1e-91 305.5 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 VBB27989.1 - 1.4e-10 41.6 0.0 2.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF594 PF04578.13 VBB27989.1 - 0.52 9.9 1.8 0.63 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF594 Tir_receptor_C PF07489.11 VBB27989.1 - 3.4 7.6 4.7 5.5 6.9 4.7 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus IPPT PF01715.17 VBB27990.1 - 1e-55 189.0 1.6 1.7e-55 188.3 1.6 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 VBB27990.1 - 1e-05 25.0 0.2 2.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 VBB27990.1 - 0.00011 22.4 1.9 0.00012 22.2 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB27990.1 - 0.00042 20.6 0.7 0.00042 20.6 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 VBB27990.1 - 0.0031 17.6 0.9 0.014 15.5 0.9 2.1 1 0 0 1 1 1 1 DBF zinc finger zf-U1 PF06220.12 VBB27990.1 - 0.0053 16.5 0.6 0.014 15.1 0.6 1.8 1 0 0 1 1 1 1 U1 zinc finger AAA_33 PF13671.6 VBB27990.1 - 0.0072 16.5 0.1 0.46 10.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain CpXC PF14353.6 VBB27990.1 - 0.047 13.7 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 CpXC protein zf-C2H2_2 PF12756.7 VBB27990.1 - 0.094 13.1 2.0 0.51 10.7 0.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) AAA_28 PF13521.6 VBB27990.1 - 0.12 12.6 0.0 0.8 9.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 VBB27990.1 - 0.16 12.5 3.6 3.3 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain RdRP_1 PF00680.20 VBB27991.1 - 0.054 12.0 0.1 0.076 11.5 0.1 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase PID PF00640.23 VBB27992.1 - 1.6e-38 131.9 0.0 1.7e-28 99.4 0.0 2.8 2 1 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 VBB27992.1 - 0.0041 17.3 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosine-binding domain GOLGA2L5 PF15070.6 VBB27994.1 - 2.4e-34 119.0 62.9 1.4e-24 86.7 9.3 4.0 1 1 0 2 2 2 2 Putative golgin subfamily A member 2-like protein 5 ZapB PF06005.12 VBB27994.1 - 0.02 15.3 0.7 0.02 15.3 0.7 8.0 3 2 3 6 6 6 0 Cell division protein ZapB AAA_24 PF13479.6 VBB27994.1 - 0.022 14.5 1.6 0.072 12.8 1.6 1.8 1 0 0 1 1 1 0 AAA domain DUF1308 PF07000.11 VBB27995.1 - 2e-60 203.4 0.1 2e-60 203.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 VBB27995.1 - 6.3e-23 81.2 0.1 1.4e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5614) LRR_8 PF13855.6 VBB27995.1 - 9.5e-18 63.7 9.9 2.6e-08 33.5 2.7 3.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 VBB27995.1 - 1e-11 44.8 21.9 0.00013 22.2 0.9 4.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB27995.1 - 2.7e-08 33.2 7.9 0.57 10.4 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 VBB27995.1 - 0.0015 18.1 2.9 0.034 13.7 2.8 2.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 VBB27995.1 - 0.0015 18.8 17.1 1.1 10.1 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat WD40 PF00400.32 VBB27996.1 - 1.3e-30 105.0 12.4 8.8e-05 23.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB27996.1 - 3.6e-16 59.2 0.2 0.00015 22.0 0.0 5.7 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB27996.1 - 3.4e-09 36.5 0.4 1.5e-06 27.8 0.2 2.5 1 1 0 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 VBB27996.1 - 7.7e-07 28.9 0.3 1e-06 28.5 0.3 1.2 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 VBB27996.1 - 1.2e-06 28.1 0.4 1.5 8.9 0.0 4.7 4 0 0 4 4 4 2 PQQ enzyme repeat VID27 PF08553.10 VBB27996.1 - 2.3e-06 27.0 0.3 5.7e-05 22.3 0.3 2.4 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain DUF5046 PF16465.5 VBB27996.1 - 2e-05 24.2 1.3 0.056 12.9 0.2 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 VBB27996.1 - 0.00059 18.9 0.6 0.51 9.2 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 VBB27996.1 - 0.00062 20.2 0.3 17 6.1 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain eIF2A PF08662.11 VBB27996.1 - 0.0095 15.8 0.1 3.5 7.5 0.0 3.4 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 VBB27996.1 - 0.017 15.2 0.3 2.2 8.4 0.0 3.0 2 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.14 VBB27996.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Frtz PF11768.8 VBB27996.1 - 0.046 12.0 0.0 0.21 9.8 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Homeodomain PF00046.29 VBB27997.1 - 2.3e-22 78.6 4.5 3.9e-22 77.9 4.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB27997.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain TUDOR PF00567.24 VBB27998.1 - 7.4e-17 61.5 0.0 2.3e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Tudor domain DDHD PF02862.17 VBB27999.1 - 1.5e-37 130.0 1.0 2.6e-37 129.1 0.0 2.0 2 1 0 2 2 2 1 DDHD domain 7tm_1 PF00001.21 VBB28000.1 - 1.7e-30 106.3 22.3 1.3e-28 100.1 22.3 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB28000.1 - 0.00012 21.8 11.2 0.00012 21.8 11.2 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 VBB28000.1 - 0.0028 17.1 18.3 0.003 17.0 11.1 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM43 PF07787.12 VBB28000.1 - 0.089 12.2 0.2 0.089 12.2 0.2 2.2 3 0 0 3 3 3 0 Transmembrane protein 43 PAP2_C PF14360.6 VBB28003.1 - 3.7e-25 88.3 8.4 3.7e-25 88.3 8.4 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 VBB28003.1 - 2.6e-07 30.5 6.9 2.6e-07 30.5 6.9 2.5 2 1 0 2 2 2 1 PAP2 superfamily EB PF01683.18 VBB28004.1 - 1.6e-38 130.7 92.1 3.9e-09 36.7 10.7 7.9 2 1 6 8 8 8 7 EB module CBFD_NFYB_HMF PF00808.23 VBB28005.1 - 6.4e-17 61.6 1.5 9.7e-17 61.0 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MutS_I PF01624.20 VBB28005.1 - 0.00098 19.4 0.1 0.0045 17.2 0.0 1.9 2 0 0 2 2 2 1 MutS domain I Histone PF00125.24 VBB28005.1 - 0.0014 19.0 0.7 0.0029 17.9 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 VBB28005.1 - 0.031 14.5 2.1 0.083 13.1 0.1 2.1 2 0 0 2 2 2 0 CENP-W protein zf-MYND PF01753.18 VBB28006.1 - 0.00042 20.3 18.2 0.00086 19.4 18.2 1.5 1 0 0 1 1 1 1 MYND finger DUF5050 PF16472.5 VBB28006.1 - 0.019 14.2 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Cadherin_2 PF08266.12 VBB28008.1 - 0.047 13.5 0.1 3.5 7.5 0.3 2.4 2 1 0 2 2 2 0 Cadherin-like DAGK_acc PF00609.19 VBB28009.1 - 1.7e-36 126.0 0.0 2.6e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 VBB28009.1 - 1.1e-22 80.0 0.0 1.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 VBB28009.1 - 3.9e-08 33.1 7.1 3.9e-08 33.1 7.1 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_kinase PF01513.21 VBB28009.1 - 0.015 14.5 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Chorion_1 PF01723.16 VBB28009.1 - 0.021 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Chorion protein C1_2 PF03107.16 VBB28009.1 - 0.033 14.5 7.3 0.033 14.5 7.3 2.4 2 0 0 2 2 2 0 C1 domain NO_synthase PF02898.15 VBB28009.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain TAF4 PF05236.14 VBB28010.1 - 1.6e-28 100.2 6.8 1.6e-28 100.2 6.8 2.8 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 VBB28010.1 - 7.9e-23 80.4 0.4 2e-22 79.1 0.4 1.7 1 0 0 1 1 1 1 NHR1 homology to TAF PEX11 PF05648.14 VBB28010.1 - 0.0063 16.0 1.8 0.03 13.8 0.1 2.2 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF5383 PF17355.2 VBB28010.1 - 0.056 13.8 0.7 0.16 12.4 0.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5383) TipAS PF07739.13 VBB28010.1 - 0.14 12.7 0.2 0.14 12.7 0.2 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain CDT1_C PF16679.5 VBB28010.1 - 5.5 7.5 7.8 0.33 11.4 0.7 2.6 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain PGAP1 PF07819.13 VBB28011.1 - 4.5e-59 200.0 0.0 8.5e-59 199.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 VBB28011.1 - 0.00065 19.6 0.0 0.00089 19.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 VBB28011.1 - 0.00075 20.2 0.0 0.00098 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 VBB28011.1 - 0.0025 17.2 0.0 0.8 9.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 VBB28011.1 - 0.0025 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 VBB28011.1 - 0.0092 15.6 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 VBB28011.1 - 0.018 14.7 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold LCAT PF02450.15 VBB28011.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 VBB28011.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf_CCCH_5 PF18384.1 VBB28012.1 - 1.6e-18 66.5 13.9 1.6e-18 66.5 13.9 2.8 2 1 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 VBB28012.1 - 0.0023 17.8 0.2 0.0023 17.8 0.2 6.3 6 1 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB28012.1 - 0.069 13.2 0.0 0.069 13.2 0.0 5.5 5 0 0 5 5 5 0 Zinc finger domain DUF3584 PF12128.8 VBB28012.1 - 0.16 9.4 4.9 0.23 9.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Torus PF16131.5 VBB28012.1 - 0.29 11.8 0.1 0.29 11.8 0.1 5.4 4 2 1 5 5 5 0 Torus domain ER_lumen_recept PF00810.18 VBB28013.1 - 4.1e-14 53.6 0.2 4.1e-14 53.6 0.2 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor DsbD_2 PF13386.6 VBB28013.1 - 0.043 13.8 0.2 0.046 13.6 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF485 PF04341.12 VBB28013.1 - 0.075 13.0 0.3 0.075 13.0 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF485 ECR1_N PF14382.6 VBB28013.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region VHP PF02209.19 VBB28014.1 - 1.4e-13 50.6 1.3 2.7e-13 49.7 1.3 1.5 1 0 0 1 1 1 1 Villin headpiece domain AbLIM_anchor PF16182.5 VBB28014.1 - 1.1e-05 25.4 1.6 1.9e-05 24.7 1.6 1.5 1 1 0 1 1 1 1 Putative adherens-junction anchoring region of AbLIM Globin PF00042.22 VBB28015.1 - 3.7e-05 24.2 0.0 5.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Globin Pkinase PF00069.25 VBB28017.1 - 8.7e-65 218.7 0.0 6.9e-51 173.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28017.1 - 4.6e-27 94.9 0.0 2.4e-19 69.6 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 VBB28017.1 - 0.0026 17.2 0.2 0.0057 16.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB28017.1 - 0.0061 15.4 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase CaMKII_AD PF08332.10 VBB28018.1 - 1.1e-56 190.5 0.0 1.8e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 VBB28018.1 - 8.7e-09 35.7 0.0 2.5e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 VBB28018.1 - 6e-08 33.0 0.0 3e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain EF-hand_1 PF00036.32 VBB28020.1 - 1.5e-40 133.7 12.3 4.5e-10 38.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB28020.1 - 3e-34 117.3 5.5 7.2e-18 64.8 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB28020.1 - 2.3e-30 104.2 13.2 3.6e-13 49.1 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 VBB28020.1 - 8.9e-30 100.1 6.5 4.2e-09 35.6 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 VBB28020.1 - 5.9e-22 76.1 7.2 1.2e-05 24.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 VBB28020.1 - 2.7e-12 46.8 0.2 4.2e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 VBB28020.1 - 4.8e-09 36.1 1.6 0.003 17.5 0.1 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 VBB28020.1 - 2.5e-05 24.2 0.0 0.83 9.7 0.0 3.2 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 VBB28020.1 - 0.00017 21.9 0.2 0.15 12.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 VBB28020.1 - 0.00036 21.4 0.1 0.0074 17.1 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 VBB28020.1 - 0.0012 18.9 1.2 0.0023 18.0 0.5 1.9 1 1 0 1 1 1 1 Ca2+ insensitive EF hand Caleosin PF05042.13 VBB28020.1 - 0.01 15.8 1.4 11 5.9 0.0 3.6 1 1 3 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 VBB28020.1 - 0.027 14.6 1.8 1.3 9.2 0.3 2.9 1 1 1 2 2 2 0 Dockerin type I domain DUF4891 PF16232.5 VBB28020.1 - 0.035 14.6 0.0 5 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4891) DUF4497 PF14924.6 VBB28020.1 - 0.035 14.6 0.0 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) p25-alpha PF05517.12 VBB28020.1 - 0.067 13.4 0.4 14 5.8 0.0 2.8 2 1 1 3 3 3 0 p25-alpha PMBR PF09373.10 VBB28020.1 - 0.084 13.1 0.9 80 3.7 0.0 4.2 6 0 0 6 6 5 0 Pseudomurein-binding repeat Got1 PF04178.12 VBB28021.1 - 4.4e-20 72.2 7.5 7.4e-20 71.5 7.5 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Oxidored_q4 PF00507.19 VBB28021.1 - 0.019 15.1 1.6 0.037 14.2 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 C1_2 PF03107.16 VBB28022.1 - 2 8.8 14.6 6.8 7.1 0.7 3.6 3 0 0 3 3 3 0 C1 domain RNHCP PF12647.7 VBB28023.1 - 6.9 6.7 7.9 7.7 6.6 0.3 3.4 3 1 1 4 4 4 0 RNHCP domain Flt3_lig PF02947.14 VBB28024.1 - 0.00092 19.4 0.2 0.27 11.4 0.0 2.2 2 0 0 2 2 2 2 flt3 ligand STAR_dimer PF16544.5 VBB28024.1 - 0.089 12.4 1.1 0.22 11.1 1.1 1.7 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein TSP_1 PF00090.19 VBB28025.1 - 0.19 12.0 2.0 19 5.6 0.6 2.5 2 0 0 2 2 2 0 Thrombospondin type 1 domain Ac110_PIF PF07280.11 VBB28026.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Per os infectivity factor AC110 Vpu PF00558.19 VBB28026.1 - 0.95 9.3 3.5 0.76 9.6 0.7 2.2 1 1 1 2 2 2 0 Vpu protein 7TM_GPCR_Srw PF10324.9 VBB28027.1 - 8.9e-32 110.6 16.0 1.2e-31 110.2 16.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw NCD2 PF04905.13 VBB28028.1 - 2.6e-53 179.2 0.1 4.5e-53 178.5 0.1 1.4 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 VBB28028.1 - 2.4e-38 130.0 0.0 4.7e-38 129.0 0.0 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Phage_HK97_TLTM PF06120.11 VBB28029.1 - 0.044 13.0 5.8 0.048 12.8 5.8 1.1 1 0 0 1 1 1 0 Tail length tape measure protein ATPase PF06745.13 VBB28029.1 - 0.055 12.8 0.6 0.058 12.7 0.6 1.2 1 0 0 1 1 1 0 KaiC CCDC144C PF14915.6 VBB28029.1 - 0.085 12.0 10.0 0.013 14.7 6.3 1.5 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Sec2p PF06428.11 VBB28029.1 - 0.36 10.8 7.1 5 7.2 3.1 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p zf-C4H2 PF10146.9 VBB28029.1 - 0.53 10.5 6.1 1.4 9.2 0.4 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 VBB28029.1 - 0.74 10.5 8.7 0.98 10.1 3.9 2.7 2 2 1 3 3 3 0 SlyX SNAPc19 PF15497.6 VBB28029.1 - 1.8 9.1 7.2 14 6.2 6.1 2.2 1 1 1 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Csm1_N PF18504.1 VBB28029.1 - 2.1 8.8 7.5 4.4 7.7 1.6 3.2 2 2 1 3 3 3 0 Csm1 N-terminal domain DUF16 PF01519.16 VBB28029.1 - 2.8 8.5 8.2 1.6 9.2 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 ENOD93 PF03386.14 VBB28032.1 - 0.22 11.4 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein LRR_6 PF13516.6 VBB28034.1 - 0.23 11.6 8.1 0.13 12.4 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich repeat MMM1 PF10296.9 VBB28035.1 - 0.023 13.7 0.3 2.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 VBB28035.1 - 0.035 14.6 0.3 0.16 12.5 0.1 2.2 2 0 0 2 2 2 0 PH domain CC PF04942.14 VBB28037.1 - 2.7e-07 30.7 112.9 0.00014 21.9 10.2 9.0 7 2 2 9 9 9 5 CC domain EB PF01683.18 VBB28037.1 - 8.5e-07 29.2 4.2 8.5e-07 29.2 4.2 7.1 3 2 1 4 4 4 1 EB module Neur_chan_memb PF02932.16 VBB28038.1 - 2.9e-30 106.1 14.5 6.8e-28 98.3 1.8 3.2 2 1 1 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 VBB28038.1 - 1.4e-25 90.0 4.1 1.8e-20 73.4 1.3 3.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain WD40 PF00400.32 VBB28039.1 - 4 8.5 7.5 1 10.4 1.3 3.3 3 1 0 3 3 3 0 WD domain, G-beta repeat RabGAP-TBC PF00566.18 VBB28040.1 - 6.3e-48 163.3 0.0 1.7e-47 161.9 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SM-ATX PF14438.6 VBB28041.1 - 7.6e-15 54.8 0.0 1.7e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 VBB28041.1 - 3.2e-06 27.6 2.3 3.2e-06 27.6 2.3 2.2 2 0 0 2 2 2 1 LsmAD domain LSM PF01423.22 VBB28041.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 LSM domain PAM2 PF07145.15 VBB28041.1 - 0.036 13.7 0.2 0.099 12.4 0.2 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DUF285 PF03382.14 VBB28041.1 - 0.16 11.7 2.7 0.083 12.7 0.4 1.6 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Occludin_ELL PF07303.13 VBB28042.1 - 1.9e-21 76.7 7.6 1.9e-21 76.7 7.6 3.1 3 0 0 3 3 3 1 Occludin homology domain ELL PF10390.9 VBB28042.1 - 3.7e-20 72.6 8.8 3.7e-20 72.6 8.8 2.5 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Fe-S_biosyn PF01521.20 VBB28042.1 - 0.017 15.3 0.3 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 Iron-sulphur cluster biosynthesis CLU_N PF15044.6 VBB28042.1 - 0.036 14.4 0.5 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term CdiI_2 PF18593.1 VBB28042.1 - 1.6 9.4 5.0 4.7 7.9 0.1 3.2 4 0 0 4 4 4 0 CdiI immunity protein Ras PF00071.22 VBB28043.1 - 2.2e-55 186.7 1.0 9.6e-53 178.1 1.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB28043.1 - 4.6e-30 104.3 0.6 6.5e-19 68.3 0.1 2.6 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28043.1 - 7.5e-12 45.1 0.3 5.9e-11 42.1 0.3 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB28043.1 - 8.3e-07 29.1 0.2 0.019 14.9 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 VBB28043.1 - 0.00093 18.8 0.0 0.0026 17.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB28043.1 - 0.0076 16.3 0.0 2.5 8.2 0.0 2.4 1 1 2 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 VBB28043.1 - 0.017 15.5 0.0 0.022 15.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 VBB28043.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.7 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 VBB28043.1 - 0.026 14.9 0.1 0.3 11.5 0.1 2.2 1 1 1 2 2 2 0 RNA helicase Gtr1_RagA PF04670.12 VBB28043.1 - 0.034 13.5 0.8 2.4 7.4 0.0 2.1 1 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA PF00004.29 VBB28043.1 - 0.045 14.2 0.0 1.7 9.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 VBB28043.1 - 0.058 12.8 0.0 0.76 9.2 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 VBB28043.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 VBB28043.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 VBB28043.1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 VBB28043.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region LANC_like PF05147.13 VBB28043.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein NACHT PF05729.12 VBB28043.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain VWA PF00092.28 VBB28044.1 - 8.4e-49 166.2 6.7 1.5e-30 106.7 0.6 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 VBB28044.1 - 4.8e-17 62.6 0.0 6.9e-08 33.1 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 VBB28044.1 - 3.1e-06 27.2 0.0 0.00027 20.9 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 VBB28044.1 - 0.0028 17.1 0.0 0.01 15.2 0.1 1.9 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Myb_DNA-binding PF00249.31 VBB28045.1 - 3.9e-06 27.0 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.8 VBB28045.1 - 0.001 19.3 3.0 0.0024 18.1 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB28045.1 - 0.0024 17.8 2.7 0.0074 16.3 2.7 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 VBB28045.1 - 0.0042 17.4 1.9 0.011 16.0 1.9 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 VBB28045.1 - 0.013 16.3 2.3 0.013 16.3 2.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger SUIM_assoc PF16619.5 VBB28045.1 - 0.045 13.8 3.0 0.062 13.4 0.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF111 PF01969.17 VBB28045.1 - 9.3 5.2 7.3 17 4.4 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 Ly-6_related PF06579.12 VBB28046.1 - 1.5e-30 106.0 0.1 1.7e-30 105.8 0.1 1.0 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 VBB28046.1 - 0.031 14.5 0.1 0.94 9.8 0.0 2.1 2 0 0 2 2 2 0 Sleepless protein LRR_8 PF13855.6 VBB28048.1 - 4.2e-17 61.7 14.3 2.4e-13 49.6 7.8 4.1 2 1 2 4 4 4 3 Leucine rich repeat ig PF00047.25 VBB28048.1 - 6.2e-07 29.5 0.2 1.4e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 VBB28048.1 - 2.7e-05 24.1 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 VBB28048.1 - 4e-05 23.2 0.2 0.00035 20.1 0.2 2.2 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 VBB28048.1 - 4.7e-05 23.7 21.0 0.00093 19.6 2.7 4.5 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 VBB28048.1 - 9e-05 23.0 0.1 0.00023 21.7 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain 7tm_2 PF00002.24 VBB28048.1 - 0.00031 20.1 12.7 0.0076 15.6 12.7 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ig_2 PF13895.6 VBB28048.1 - 0.00039 20.7 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB28048.1 - 0.099 12.8 0.1 0.79 9.9 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_1 PF00560.33 VBB28048.1 - 0.86 10.4 24.8 0.5 11.1 0.2 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat Ets PF00178.22 VBB28050.1 - 2.3e-36 124.1 0.5 3.6e-36 123.5 0.5 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 VBB28050.1 - 0.059 14.0 0.1 0.074 13.7 0.1 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding PAN_3 PF08277.12 VBB28051.1 - 0.092 12.6 0.5 0.28 11.0 0.5 1.9 1 0 0 1 1 1 0 PAN-like domain WDCP PF15390.6 VBB28051.1 - 2.3 6.5 8.2 2.7 6.3 8.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family RNA_pol_Rpc4 PF05132.14 VBB28053.1 - 1.8e-11 44.7 0.4 1.6e-10 41.6 0.4 2.8 1 1 0 1 1 1 1 RNA polymerase III RPC4 DNA_PPF PF02916.15 VBB28053.1 - 0.2 12.1 1.5 0.62 10.5 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase processivity factor MIF PF01187.18 VBB28054.1 - 2.2e-11 44.0 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF108 PF01958.18 VBB28054.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF108 Peptidase_M18 PF02127.15 VBB28056.1 - 6.2e-165 549.2 0.4 7.5e-165 548.9 0.4 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 VBB28056.1 - 8.1e-06 25.1 0.3 0.0034 16.5 0.2 2.7 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase Ribosomal_L36e PF01158.18 VBB28057.1 - 5.4e-40 135.5 9.5 5.4e-40 135.5 9.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L36e PP-binding PF00550.25 VBB28057.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site EI24 PF07264.11 VBB28057.1 - 9.7e-06 25.9 0.4 9.7e-06 25.9 0.4 2.4 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Ribosomal_S11 PF00411.19 VBB28058.1 - 2.1e-45 153.6 1.5 2.6e-45 153.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 VBB28058.1 - 0.082 12.0 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Runt PF00853.19 VBB28060.1 - 8.1e-57 190.4 0.1 1.2e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 Runt domain RRM_7 PF16367.5 VBB28061.1 - 1.3e-30 105.4 0.2 4.4e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 VBB28061.1 - 1.3e-22 79.7 6.3 3.6e-22 78.3 6.3 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 VBB28061.1 - 1.1e-07 31.5 0.0 0.00036 20.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1830 PF08865.11 VBB28061.1 - 0.0084 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1830) RB_A PF01858.17 VBB28062.1 - 3.6e-48 164.0 3.8 7.8e-48 162.9 3.2 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 VBB28062.1 - 2e-38 131.4 0.0 6.5e-38 129.8 0.0 1.9 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 VBB28062.1 - 1.1e-24 86.6 1.5 1.1e-24 86.6 1.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) TFIIB PF00382.19 VBB28062.1 - 0.023 14.7 0.0 0.98 9.5 0.0 3.0 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Cation_efflux PF01545.21 VBB28063.1 - 2.4e-49 167.8 13.6 2.4e-49 167.8 13.6 2.8 2 1 0 2 2 2 1 Cation efflux family CPSF73-100_C PF11718.8 VBB28063.1 - 0.041 13.4 0.2 0.078 12.5 0.2 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Neur_chan_LBD PF02931.23 VBB28064.1 - 9.8e-14 51.3 0.6 1.9e-13 50.4 0.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB28064.1 - 1.5e-05 25.2 2.8 2e-05 24.8 2.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_phi PF04931.13 VBB28065.1 - 0.48 8.5 22.7 0.54 8.3 22.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 VBB28065.1 - 1.4 8.2 27.5 1.6 8.0 27.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 VBB28065.1 - 2.7 7.0 28.5 3 6.9 28.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 VBB28065.1 - 5.6 6.5 20.5 6.4 6.3 20.5 1.1 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 VBB28065.1 - 7.2 6.6 17.1 10 6.1 17.1 1.3 1 1 0 1 1 1 0 RXT2-like, N-terminal PDZ PF00595.24 VBB28068.1 - 1.6e-20 73.3 0.2 2.3e-20 72.7 0.2 1.2 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 VBB28068.1 - 3.2e-15 55.6 0.0 5.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 L27 domain PDZ_6 PF17820.1 VBB28068.1 - 3e-12 46.2 0.2 7.1e-12 45.0 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB28068.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain His_Phos_2 PF00328.22 VBB28068.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) HECT PF00632.25 VBB28069.1 - 1.1e-78 264.8 0.0 1.7e-78 264.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 VBB28069.1 - 0.0062 16.2 2.1 0.016 14.9 2.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif W2 PF02020.18 VBB28070.1 - 3.1e-16 59.3 0.2 7e-16 58.1 0.2 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 VBB28070.1 - 4e-06 26.3 11.8 0.0077 15.9 2.5 3.2 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 VBB28070.1 - 6.7e-06 24.5 1.9 1.7e-05 23.2 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 VBB28070.1 - 0.0035 16.3 0.2 0.0065 15.5 0.2 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 VBB28070.1 - 0.28 11.0 19.1 0.28 11.0 6.4 3.9 1 1 3 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF1908 PF08926.11 VBB28071.1 - 6.6e-65 219.0 8.5 3.9e-40 137.7 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF1908) Pkinase PF00069.25 VBB28071.1 - 2e-62 210.9 0.0 7.2e-62 209.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28071.1 - 1.6e-28 99.7 0.0 3.7e-28 98.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.24 VBB28071.1 - 2.2e-07 31.1 0.0 6.2e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB28071.1 - 8.2e-07 28.8 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 VBB28071.1 - 2.1e-05 24.6 0.1 0.088 12.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB28071.1 - 3.9e-05 23.1 0.0 0.00021 20.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PDZ_2 PF13180.6 VBB28071.1 - 4.7e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Haspin_kinase PF12330.8 VBB28071.1 - 0.019 13.9 0.1 0.019 13.9 0.1 2.4 2 1 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB28071.1 - 0.093 11.5 0.0 0.21 10.3 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase Band_7 PF01145.25 VBB28072.1 - 4.3e-23 82.2 0.8 6.9e-23 81.6 0.8 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 VBB28072.1 - 0.051 13.7 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 SNase PF00565.17 VBB28072.1 - 0.19 12.2 1.4 1.5 9.3 0.0 2.7 2 1 0 2 2 2 0 Staphylococcal nuclease homologue DB PF01682.19 VBB28073.1 - 4.5e-20 71.8 13.6 4.5e-20 71.8 13.6 1.9 2 0 0 2 2 2 1 DB module Ribosomal_L27e PF01777.18 VBB28073.1 - 1.7 9.1 5.5 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family TERB2 PF15101.6 VBB28073.1 - 2 8.4 9.6 3.9 7.5 9.6 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MAP65_ASE1 PF03999.12 VBB28073.1 - 5.1 5.7 21.9 6.4 5.3 21.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Neocarzinostat PF00960.18 VBB28073.1 - 6.9 6.7 6.9 0.43 10.6 0.9 2.0 2 0 0 2 2 2 0 Neocarzinostatin family Presenilin PF01080.17 VBB28073.1 - 7.3 5.2 6.4 8.4 5.0 6.4 1.2 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 VBB28073.1 - 8 5.4 8.8 13 4.7 8.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein C2 PF00168.30 VBB28074.1 - 2.5e-42 143.4 0.4 5.8e-13 49.0 0.0 7.3 6 1 0 6 6 6 5 C2 domain Ferlin_C PF16165.5 VBB28074.1 - 8e-24 84.3 0.0 2e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Ferlin C-terminus FerB PF08150.12 VBB28074.1 - 3.1e-19 69.3 0.0 8.4e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain Pex24p PF06398.11 VBB28074.1 - 8e-06 25.1 13.2 0.0036 16.3 13.2 2.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Na_Ca_ex PF01699.24 VBB28075.1 - 2.7e-48 163.8 56.1 6.3e-27 94.4 21.8 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cadherin_C_2 PF16492.5 VBB28075.1 - 0.076 13.8 0.8 0.076 13.8 0.8 3.4 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Bax1-I PF01027.20 VBB28076.1 - 1.7e-45 155.4 18.2 1.7e-45 155.4 18.2 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 BolA PF01722.18 VBB28077.1 - 8e-26 90.1 0.1 1.1e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein Peptidase_M41 PF01434.18 VBB28078.1 - 5e-61 205.9 0.2 1.3e-60 204.5 0.1 1.7 1 1 1 2 2 2 1 Peptidase family M41 AAA PF00004.29 VBB28078.1 - 1.1e-40 139.2 0.1 1.7e-38 132.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB28078.1 - 4.9e-11 42.2 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 VBB28078.1 - 5.1e-05 23.6 0.2 0.018 15.3 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 VBB28078.1 - 0.00011 22.3 0.0 0.00045 20.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 VBB28078.1 - 0.00017 22.1 0.1 0.0012 19.2 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 VBB28078.1 - 0.00024 21.1 0.1 0.0027 17.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 VBB28078.1 - 0.00024 21.5 0.7 0.00047 20.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 VBB28078.1 - 0.0016 18.2 0.0 0.0067 16.2 0.0 2.1 3 0 0 3 3 3 1 IstB-like ATP binding protein TIP49 PF06068.13 VBB28078.1 - 0.0018 17.5 0.1 0.005 16.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 VBB28078.1 - 0.0019 18.4 0.1 0.0073 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 VBB28078.1 - 0.0034 17.2 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 VBB28078.1 - 0.004 17.7 0.2 0.025 15.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 VBB28078.1 - 0.0041 17.2 0.0 0.042 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 VBB28078.1 - 0.0069 16.0 0.1 0.024 14.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 VBB28078.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 VBB28078.1 - 0.028 13.7 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 VBB28078.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 VBB28078.1 - 0.032 13.6 0.1 0.063 12.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HhH-GPD PF00730.25 VBB28078.1 - 0.043 14.3 0.0 9.9 6.7 0.1 2.9 2 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Coiled-coil_56 PF09813.9 VBB28078.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Sigma54_activat PF00158.26 VBB28078.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 VBB28078.1 - 0.076 13.1 0.4 0.71 10.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 VBB28078.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 VBB28078.1 - 0.13 12.2 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain 6PGD PF00393.19 VBB28079.1 - 9.1e-122 406.0 0.0 1.3e-121 405.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 VBB28079.1 - 8.3e-51 172.3 0.0 1.2e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 VBB28079.1 - 0.00014 21.9 0.2 0.00023 21.2 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 VBB28079.1 - 0.019 15.5 0.1 0.038 14.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 VBB28079.1 - 0.034 13.7 0.3 0.29 10.7 0.0 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_11 PF14833.6 VBB28079.1 - 0.079 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Ank_2 PF12796.7 VBB28080.1 - 3.7e-23 81.9 3.6 6.5e-15 55.5 0.5 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB28080.1 - 1e-19 70.6 2.8 1.8e-09 37.9 0.2 4.2 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB28080.1 - 7.9e-19 67.5 5.5 9.6e-07 29.0 0.3 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 VBB28080.1 - 1.8e-18 66.1 4.3 2.3e-06 27.8 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 VBB28080.1 - 1e-15 56.2 0.5 0.00012 22.2 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Glyco_hydro_20b PF02838.15 VBB28080.1 - 0.00015 22.5 0.0 0.00043 21.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 VBB28080.1 - 0.0078 16.9 0.1 0.049 14.3 0.0 2.2 1 1 0 2 2 2 1 beta-acetyl hexosaminidase like CSN8_PSD8_EIF3K PF10075.9 VBB28081.1 - 8e-16 58.3 0.0 2.6e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Epimerase PF01370.21 VBB28082.1 - 5e-22 78.6 0.0 6.4e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 VBB28082.1 - 3.5e-15 56.2 0.3 1.7e-14 54.0 0.3 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 VBB28082.1 - 2e-10 40.2 0.0 2.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 VBB28082.1 - 4.6e-06 26.0 0.0 2.7e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 VBB28082.1 - 5.7e-06 25.5 0.0 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 VBB28082.1 - 5.1e-05 22.5 0.8 0.00045 19.4 0.8 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ER_lumen_recept PF00810.18 VBB28083.1 - 1e-53 182.2 10.8 1e-53 182.2 10.8 2.2 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF21 PF01595.20 VBB28083.1 - 2.3e-23 82.8 6.9 2.3e-23 82.8 6.9 2.0 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 VBB28083.1 - 1.9e-05 25.0 0.1 0.24 11.9 0.0 3.1 2 0 0 2 2 2 2 CBS domain DUF3368 PF11848.8 VBB28083.1 - 0.023 14.5 0.1 0.094 12.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) DUF2312 PF10073.9 VBB28083.1 - 0.045 13.4 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TPR_6 PF13174.6 VBB28083.1 - 0.14 12.9 0.0 3.6 8.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Astacin PF01400.24 VBB28084.1 - 2e-64 216.7 0.0 3.7e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 VBB28084.1 - 0.00035 19.6 0.2 0.0007 18.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 VBB28084.1 - 0.0015 18.4 0.9 0.88 9.4 0.1 2.3 2 0 0 2 2 2 2 Matrixin CUB PF00431.20 VBB28084.1 - 0.02 15.2 0.2 0.046 14.1 0.2 1.6 1 0 0 1 1 1 0 CUB domain Reprolysin_4 PF13583.6 VBB28084.1 - 0.029 14.0 0.1 0.28 10.8 0.1 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 VBB28084.1 - 0.1 11.2 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M57 PF12388.8 VBB28084.1 - 0.17 11.5 0.3 0.33 10.5 0.3 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase WD40 PF00400.32 VBB28085.1 - 2.4e-07 31.3 4.2 0.1 13.5 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28085.1 - 3.5e-06 27.2 0.7 0.0098 16.2 0.1 4.0 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1433 PF07252.11 VBB28085.1 - 0.12 12.6 0.7 0.22 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) zf-C2H2_4 PF13894.6 VBB28086.1 - 2.9e-08 33.9 35.3 0.12 13.3 0.7 6.7 6 0 0 6 6 6 5 C2H2-type zinc finger MCM_OB PF17207.3 VBB28086.1 - 0.00062 19.6 5.3 0.023 14.5 0.6 2.7 2 0 0 2 2 2 2 MCM OB domain zf-C2H2 PF00096.26 VBB28086.1 - 0.004 17.5 45.6 0.0041 17.5 1.2 6.2 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 VBB28086.1 - 0.012 15.4 28.4 0.031 14.0 0.5 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 VBB28086.1 - 0.013 15.9 7.9 0.019 15.4 4.7 5.8 7 0 0 7 7 7 0 Zinc-finger double domain Ocnus PF05005.15 VBB28087.1 - 2.7e-78 259.0 2.0 7.6e-39 132.1 0.2 2.0 2 0 0 2 2 2 2 Janus/Ocnus family (Ocnus) AAA_17 PF13207.6 VBB28087.1 - 0.027 14.9 0.0 6.7 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Eno-Rase_NADH_b PF12242.8 VBB28087.1 - 0.17 11.6 0.2 5.4 6.9 0.0 2.5 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_TACC PF12709.7 VBB28087.1 - 0.85 10.1 8.2 0.5 10.8 0.9 2.8 2 2 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2043 PF09740.9 VBB28088.1 - 6.8e-36 123.2 1.4 3.4e-35 120.9 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) DUF848 PF05852.11 VBB28088.1 - 0.23 11.6 8.1 3.2 7.8 0.1 2.9 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Cofilin_ADF PF00241.20 VBB28089.1 - 1.3e-29 102.4 0.2 1.6e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 VBB28090.1 - 1.4e-159 531.9 2.4 1.8e-159 531.6 2.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Calx-beta PF03160.14 VBB28091.1 - 1.1e-53 179.5 0.7 4e-28 97.5 0.2 2.7 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 VBB28091.1 - 2.3e-53 180.2 28.5 1.3e-26 93.4 11.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 VBB28091.1 - 3.5e-28 98.6 0.8 6.6e-28 97.7 0.8 1.5 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain MarB PF13999.6 VBB28091.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 MarB protein PI-PLC-X PF00388.19 VBB28092.1 - 2.1e-47 160.4 0.0 3.5e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 VBB28092.1 - 2.1e-20 72.6 0.6 4.9e-20 71.4 0.6 1.7 1 0 0 1 1 1 1 SH2 domain PI-PLC-Y PF00387.19 VBB28093.1 - 9e-42 142.1 0.6 1.6e-41 141.3 0.6 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.24 VBB28093.1 - 2.5e-17 62.7 0.2 7.2e-17 61.3 0.2 1.8 1 0 0 1 1 1 1 SH2 domain C2 PF00168.30 VBB28093.1 - 7.4e-15 55.1 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 VBB28093.1 - 2e-06 28.3 0.0 5.8e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 PH domain SH3_2 PF07653.17 VBB28093.1 - 3.2e-06 26.7 0.0 7.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB28093.1 - 2.3e-05 23.9 0.0 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB28093.1 - 0.00033 20.5 0.2 0.0009 19.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Forkhead PF00250.18 VBB28094.1 - 6.3e-37 125.7 0.0 1e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Ets PF00178.22 VBB28097.1 - 1.1e-27 96.3 0.3 2.2e-27 95.3 0.3 1.5 1 0 0 1 1 1 1 Ets-domain DUF829 PF05705.14 VBB28098.1 - 2.9e-48 164.9 2.1 3.3e-48 164.7 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Jun PF03957.13 VBB28099.1 - 4.1e-08 33.4 7.7 4.1e-08 33.4 7.7 2.3 1 1 1 2 2 2 1 Jun-like transcription factor Phage_holin_3_2 PF04550.12 VBB28099.1 - 0.081 13.5 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 Phage holin family 2 Pkinase PF00069.25 VBB28101.1 - 3.4e-42 144.6 0.0 6e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28101.1 - 6.1e-41 140.4 0.0 9e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB28101.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB28101.1 - 0.0009 18.1 0.0 0.002 17.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase zf-U11-48K PF05253.12 VBB28102.1 - 0.00021 21.2 10.0 0.017 15.0 0.9 3.2 3 0 0 3 3 3 3 U11-48K-like CHHC zinc finger DRIM PF07539.12 VBB28103.1 - 3e-44 151.4 7.9 2.7e-42 144.9 0.7 3.1 3 1 0 3 3 3 2 Down-regulated in metastasis LRR_8 PF13855.6 VBB28104.1 - 2.8e-138 449.8 140.6 1.6e-12 46.9 4.3 19.7 12 6 8 20 20 20 19 Leucine rich repeat LRR_4 PF12799.7 VBB28104.1 - 5.8e-61 201.4 159.9 9.4e-06 25.9 0.2 24.1 12 4 17 30 30 30 26 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB28104.1 - 6e-48 162.0 28.3 3.2e-07 30.4 1.2 9.5 3 1 7 10 10 10 8 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB28104.1 - 4e-23 81.8 77.1 1.1e-05 25.1 0.1 10.0 2 2 7 10 10 10 10 Leucine-rich repeat LRR_1 PF00560.33 VBB28104.1 - 7.8e-14 50.1 128.0 2.6 8.9 0.0 32.2 36 4 1 37 37 37 8 Leucine Rich Repeat LRR_6 PF13516.6 VBB28104.1 - 7.8e-14 50.5 106.6 0.56 10.4 0.2 27.6 31 0 0 31 31 31 10 Leucine Rich repeat DRIM PF07539.12 VBB28105.1 - 1.4e-42 145.9 12.2 2.5e-42 145.0 12.2 1.4 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.22 VBB28105.1 - 0.052 13.8 8.9 6 7.4 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat DUF5641 PF18701.1 VBB28106.1 - 1.4e-08 34.8 0.0 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Pox_D2 PF04701.13 VBB28106.1 - 0.041 14.1 0.3 0.058 13.6 0.3 1.3 1 0 0 1 1 1 0 Pox virus D2 protein PhoLip_ATPase_C PF16212.5 VBB28107.1 - 1.7e-55 188.5 27.8 1.6e-53 182.1 11.0 2.7 2 1 1 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 VBB28107.1 - 1e-11 44.8 0.0 1.5e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 VBB28107.1 - 7e-11 42.8 0.4 7.5e-05 23.1 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 VBB28107.1 - 7.6e-07 28.8 2.9 1.2e-06 28.2 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 VBB28107.1 - 0.0019 18.0 0.6 0.0049 16.6 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 VBB28107.1 - 0.085 13.4 0.6 0.27 11.7 0.1 2.1 2 0 0 2 2 2 0 CoA binding domain CytochromB561_N PF09786.9 VBB28109.1 - 3.7e-51 174.8 19.1 1.6e-48 166.1 0.0 2.5 2 2 0 2 2 2 2 Cytochrome B561, N terminal RasGEF PF00617.19 VBB28110.1 - 8.1e-39 133.6 0.7 1.9e-38 132.5 0.7 1.7 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 VBB28110.1 - 2.4e-17 62.8 0.0 5.4e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DEP PF00610.21 VBB28110.1 - 1.7e-11 44.0 0.1 1.7e-11 44.0 0.1 2.2 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 VBB28110.1 - 4.8e-06 26.8 0.1 2.1e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif UL41A PF17591.2 VBB28110.1 - 0.016 15.3 0.0 0.058 13.5 0.0 2.0 1 0 0 1 1 1 0 Herpesvirus UL41A IPPT PF01715.17 VBB28110.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 IPP transferase Lactamase_B_6 PF16661.5 VBB28111.1 - 9.5e-52 175.2 0.2 7.2e-49 165.9 0.0 3.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 VBB28111.1 - 5.6e-21 74.9 0.0 2.6e-20 72.8 0.0 2.2 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 VBB28111.1 - 2.1e-13 50.0 0.0 4.8e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF100_C PF13299.6 VBB28111.1 - 2.2e-07 31.2 0.3 2.2e-07 31.2 0.3 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_2 PF12706.7 VBB28111.1 - 5e-05 22.9 0.0 0.00057 19.5 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 VBB28111.1 - 0.00077 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-NOSIP PF15906.5 VBB28112.1 - 1.8e-30 104.9 0.1 3.1e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 VBB28112.1 - 2e-06 27.4 8.5 0.0012 18.3 0.1 3.1 1 1 1 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 VBB28112.1 - 5.1e-05 23.4 0.0 0.0054 16.9 0.0 3.0 2 1 0 2 2 2 1 U-box domain zf-Nse PF11789.8 VBB28112.1 - 0.003 17.4 0.8 0.11 12.3 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.32 VBB28113.1 - 2.9e-36 122.8 14.4 3.7e-07 30.7 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28113.1 - 7.3e-09 35.8 0.0 0.051 13.9 0.0 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB28113.1 - 4.9e-07 29.0 1.1 0.059 12.3 0.0 3.7 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 VBB28113.1 - 3.9e-06 26.9 0.1 0.046 13.6 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BPL_LplA_LipB PF03099.19 VBB28113.1 - 1.1e-05 25.4 0.0 3.5e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Nup160 PF11715.8 VBB28113.1 - 2e-05 23.5 0.1 5.6e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB28113.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Presenilin PF01080.17 VBB28114.1 - 5.2e-90 302.1 0.0 5.8e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Presenilin Fz PF01392.22 VBB28115.1 - 1.2e-05 25.9 1.7 3.9e-05 24.2 1.7 1.9 1 0 0 1 1 1 1 Fz domain 2Fe-2S_thioredx PF01257.19 VBB28116.1 - 3.3e-63 211.9 0.0 4e-63 211.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin zf-RanBP PF00641.18 VBB28117.1 - 9.5e-13 47.2 30.5 1.5e-05 24.2 6.5 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 VBB28117.1 - 9.4e-05 22.4 22.2 0.014 15.4 9.6 2.8 2 1 0 2 2 2 2 Double zinc ribbon DUF2116 PF09889.9 VBB28117.1 - 6.3 6.9 13.0 5.5 7.1 0.2 3.3 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) LisH PF08513.11 VBB28118.1 - 0.013 15.5 0.3 0.065 13.2 0.0 2.4 3 0 0 3 3 3 0 LisH RabGAP-TBC PF00566.18 VBB28119.1 - 8.1e-51 172.7 2.9 8.1e-51 172.7 2.9 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ELMO_CED12 PF04727.13 VBB28119.1 - 0.012 15.8 0.1 0.022 14.9 0.1 1.5 1 1 0 1 1 1 0 ELMO/CED-12 family DUF4864 PF16156.5 VBB28119.1 - 0.021 15.5 0.0 0.057 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Cullin_binding PF03556.15 VBB28119.1 - 0.045 14.2 1.4 0.068 13.6 0.2 1.9 2 0 0 2 2 2 0 Cullin binding Lactamase_B PF00753.27 VBB28121.1 - 3.7e-07 30.3 0.1 3.6e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lustrin_cystein PF14625.6 VBB28121.1 - 5.9e-06 26.5 3.5 1.3e-05 25.4 3.5 1.6 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Lactamase_B_6 PF16661.5 VBB28121.1 - 0.064 12.7 0.2 0.14 11.5 0.1 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain CPG4 PF15481.6 VBB28122.1 - 5e-08 33.5 4.2 5e-08 33.5 4.2 2.8 2 2 1 3 3 3 1 Chondroitin proteoglycan 4 Cys_box PF17869.1 VBB28122.1 - 0.27 11.4 4.9 0.15 12.2 0.5 2.6 2 1 1 3 3 3 0 Anosmin cysteine rich domain ADP_PFK_GK PF04587.15 VBB28123.1 - 1.6e-107 359.7 0.0 2.7e-107 359.0 0.0 1.3 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region RNA_pol_Rpb1_5 PF04998.17 VBB28123.1 - 2.7e-87 292.6 0.0 1e-86 290.7 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 HORMA PF02301.18 VBB28123.1 - 7.3e-20 71.5 0.0 7.3e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 HORMA domain Acyl_transf_1 PF00698.21 VBB28123.1 - 2.2e-17 63.5 0.1 8.1e-17 61.7 0.1 1.9 1 1 0 1 1 1 1 Acyl transferase domain RNA_pol_Rpb1_4 PF05000.17 VBB28123.1 - 1.9e-06 27.8 0.0 7.8e-06 25.8 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PAS_2 PF08446.11 VBB28123.1 - 0.065 13.9 0.1 0.35 11.5 0.1 2.3 1 1 0 1 1 1 0 PAS fold Helicase_C PF00271.31 VBB28125.1 - 6.1e-29 100.6 0.4 6.3e-28 97.3 0.1 2.7 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB28125.1 - 1.3e-21 77.2 0.1 3.6e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 VBB28125.1 - 0.22 11.8 2.0 0.48 10.7 0.3 2.4 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 VBB28126.1 - 2.6e-22 79.3 27.0 7.4e-13 48.1 4.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 VBB28126.1 - 0.00022 20.2 14.8 0.035 12.9 6.4 2.7 1 1 2 3 3 3 2 MFS_1 like family UNC-93 PF05978.16 VBB28126.1 - 0.05 13.3 20.2 0.027 14.2 6.4 3.2 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 DEAD PF00270.29 VBB28127.1 - 1.2e-18 67.5 0.1 2.4e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB28127.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit ETRAMP PF09716.10 VBB28127.1 - 0.13 12.4 0.4 2.2 8.4 0.6 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) EF-hand_3 PF09069.11 VBB28128.1 - 1.4e-32 112.0 0.2 9.2e-32 109.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand EF-hand_2 PF09068.11 VBB28128.1 - 6.1e-30 103.9 5.0 6.3e-30 103.9 1.7 2.8 2 0 0 2 2 2 1 EF hand ZZ PF00569.17 VBB28128.1 - 8.4e-15 54.3 6.3 1.7e-14 53.4 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Spectrin PF00435.21 VBB28128.1 - 2.9e-09 37.3 20.3 1.2e-06 28.9 3.2 10.6 10 1 1 11 11 11 5 Spectrin repeat WW PF00397.26 VBB28128.1 - 2.7e-08 33.8 1.1 5.2e-08 32.8 1.1 1.5 1 0 0 1 1 1 1 WW domain Rib_5-P_isom_A PF06026.14 VBB28128.1 - 0.011 15.3 0.2 0.11 12.1 0.2 2.5 2 0 0 2 2 2 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) IL31 PF15209.6 VBB28128.1 - 0.044 13.6 1.1 0.99 9.2 0.0 3.3 2 0 0 2 2 2 0 Interleukin 31 Herpes_BLRF2 PF05812.12 VBB28128.1 - 0.059 13.5 0.2 0.059 13.5 0.2 4.8 5 0 0 5 5 5 0 Herpesvirus BLRF2 protein Bromodomain PF00439.25 VBB28129.1 - 3.2e-21 75.2 0.3 8e-21 73.9 0.3 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 VBB28129.1 - 4.2e-18 65.0 17.6 2.8e-11 43.1 5.5 2.9 2 0 0 2 2 2 2 PHD-finger MBD PF01429.19 VBB28129.1 - 3.2e-16 58.8 0.0 8.3e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 VBB28129.1 - 9.1e-09 35.7 1.9 1.6e-08 34.9 0.0 2.6 3 0 0 3 3 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 VBB28129.1 - 5.3e-08 32.3 9.3 0.0011 18.5 1.3 2.9 2 0 0 2 2 2 2 PHD-finger DDT PF02791.17 VBB28129.1 - 0.00063 20.0 0.5 0.0026 18.0 0.5 2.2 1 0 0 1 1 1 1 DDT domain Prok-RING_1 PF14446.6 VBB28129.1 - 0.031 14.2 13.9 0.18 11.8 0.9 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 VBB28129.1 - 0.042 13.5 9.4 0.16 11.6 1.8 3.6 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 VBB28129.1 - 0.056 13.3 12.9 0.12 12.3 1.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 VBB28129.1 - 0.094 12.8 12.8 0.58 10.3 0.9 3.9 3 0 0 3 3 3 0 KIAA1045 RING finger MADF_DNA_bdg PF10545.9 VBB28129.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.6 3 0 0 3 3 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-RING_9 PF13901.6 VBB28129.1 - 3.6 7.5 16.4 3.6 7.5 6.8 2.8 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon zf-DBF PF07535.12 VBB28130.1 - 0.00019 21.5 0.4 0.00042 20.4 0.4 1.5 1 0 0 1 1 1 1 DBF zinc finger ORMDL PF04061.14 VBB28130.1 - 0.089 12.6 2.4 0.15 11.8 2.4 1.3 1 0 0 1 1 1 0 ORMDL family PHF5 PF03660.14 VBB28130.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 PHF5-like protein DUF2975 PF11188.8 VBB28130.1 - 0.94 9.4 5.9 2.2 8.2 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2070 PF09843.9 VBB28130.1 - 3.5 5.8 8.6 5 5.3 8.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) dNK PF01712.19 VBB28131.1 - 6.4e-41 140.5 0.5 1.1e-40 139.7 0.5 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 VBB28131.1 - 0.0024 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Thymidylate kinase Cytidylate_kin2 PF13189.6 VBB28131.1 - 0.026 14.6 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.22 VBB28131.1 - 0.035 14.2 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 VBB28131.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain MADF_DNA_bdg PF10545.9 VBB28132.1 - 2.6e-15 56.5 3.6 6.1e-15 55.3 3.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 VBB28132.1 - 0.00016 21.4 0.2 0.00036 20.3 0.0 1.7 2 0 0 2 2 2 1 BESS motif DUF1547 PF07577.11 VBB28132.1 - 0.028 14.8 0.7 0.084 13.3 0.7 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) SRR1 PF07985.12 VBB28133.1 - 2.2e-07 30.8 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 SRR1 SDA1 PF05285.12 VBB28134.1 - 0.36 10.2 37.0 0.41 10.0 37.0 1.1 1 0 0 1 1 1 0 SDA1 Med6 PF04934.14 VBB28137.1 - 5.5e-36 123.3 0.5 3.1e-35 120.9 0.3 2.0 2 0 0 2 2 2 1 MED6 mediator sub complex component UMP1 PF05348.11 VBB28138.1 - 7.3e-05 23.0 0.0 9.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase PF00069.25 VBB28139.1 - 1.4e-24 86.9 0.0 1.8e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28139.1 - 3.8e-14 52.6 0.0 5.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB28139.1 - 6.4e-08 31.8 0.1 9e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB28139.1 - 0.0035 16.7 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB28139.1 - 0.0036 17.3 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lipase_3 PF01764.25 VBB28140.1 - 2.3e-32 111.8 0.0 3.7e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 VBB28140.1 - 0.031 13.9 0.0 0.089 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 VBB28140.1 - 0.15 12.6 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Katanin_con80 PF13925.6 VBB28141.1 - 1.1e-27 97.1 0.1 2.5e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 VBB28141.1 - 5e-12 46.1 2.3 0.00017 22.3 0.0 4.4 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28141.1 - 0.00049 20.3 0.0 0.027 14.8 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB28141.1 - 0.0061 16.5 0.0 1 9.2 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Pkinase_Tyr PF07714.17 VBB28142.1 - 9.5e-81 270.9 0.0 1.6e-80 270.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 VBB28142.1 - 1.3e-46 157.3 2.5 3.3e-22 78.7 0.2 2.8 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 VBB28142.1 - 9.9e-40 136.6 0.0 1.7e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 VBB28142.1 - 1.8e-18 66.8 42.5 1.8e-18 66.8 42.5 6.1 3 1 3 6 6 5 2 Furin-like cysteine rich region GF_recep_IV PF14843.6 VBB28142.1 - 6.1e-16 58.4 124.2 2.9e-14 53.0 34.2 6.6 2 2 2 4 4 4 2 Growth factor receptor domain IV Haspin_kinase PF12330.8 VBB28142.1 - 0.0023 17.0 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 VBB28142.1 - 0.0024 17.2 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB28142.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 VBB28142.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 VBB28142.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4214 PF13946.6 VBB28142.1 - 0.22 11.6 0.3 0.65 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) DUF5534 PF17686.1 VBB28142.1 - 0.58 10.4 1.8 0.74 10.1 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5534) Collagen PF01391.18 VBB28143.1 - 2.7e-26 91.1 84.0 5e-10 39.0 26.1 3.5 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28143.1 - 4.8e-12 45.8 2.7 6.2e-12 45.4 2.7 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4706 PF15797.5 VBB28143.1 - 0.22 12.1 0.0 0.34 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) Pkinase_Tyr PF07714.17 VBB28145.1 - 1.6e-80 270.1 0.0 2.9e-80 269.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB28145.1 - 6.2e-45 153.6 0.0 1e-44 152.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 VBB28145.1 - 7.5e-07 29.4 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 VBB28145.1 - 6.9e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 SH2 PF00017.24 VBB28145.1 - 0.0007 19.7 0.1 0.0024 17.9 0.1 2.1 1 0 0 1 1 1 1 SH2 domain SLATT_5 PF18160.1 VBB28145.1 - 2.6 7.3 4.5 1.5 8.1 0.3 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 zf-RRPl_C4 PF17026.5 VBB28145.1 - 4.7 7.4 8.9 12 6.1 0.1 3.8 4 0 0 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type OTU PF02338.19 VBB28146.1 - 9.8e-27 94.0 0.2 3.6e-26 92.2 0.0 2.1 2 1 0 2 2 2 1 OTU-like cysteine protease DUF2804 PF10974.8 VBB28146.1 - 0.072 12.6 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Sec5 PF15469.6 VBB28147.1 - 8.8e-43 146.3 1.3 8.8e-43 146.3 1.3 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 TIG PF01833.24 VBB28147.1 - 4e-09 36.4 0.0 7.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain Sec15 PF04091.12 VBB28147.1 - 0.00057 19.4 0.9 0.00057 19.4 0.9 2.9 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like Glyco_transf_18 PF15024.6 VBB28148.1 - 2.5e-176 587.6 5.0 2.3e-101 340.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 18 DUF3677 PF12432.8 VBB28151.1 - 4.7e-23 81.3 4.3 5e-23 81.2 1.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) Prefoldin_2 PF01920.20 VBB28153.1 - 7e-23 80.6 14.9 8.5e-23 80.3 14.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.10 VBB28153.1 - 0.005 17.1 1.2 0.005 17.1 1.2 1.8 2 0 0 2 2 2 1 Osmosensory transporter coiled coil Snf7 PF03357.21 VBB28153.1 - 0.013 15.1 5.6 0.013 15.1 5.6 2.1 2 0 0 2 2 2 0 Snf7 DUF1192 PF06698.11 VBB28153.1 - 0.015 15.3 1.6 0.041 13.9 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1732 PF08340.11 VBB28153.1 - 0.017 15.1 0.5 0.017 15.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) DUF5082 PF16888.5 VBB28153.1 - 0.036 14.4 8.9 0.088 13.1 8.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ERp29 PF07749.12 VBB28153.1 - 0.048 14.6 6.5 0.11 13.4 1.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Prefoldin_3 PF13758.6 VBB28153.1 - 0.058 13.5 5.0 0.16 12.0 4.8 1.9 1 1 0 1 1 1 0 Prefoldin subunit Sec16 PF12932.7 VBB28153.1 - 0.16 12.6 0.7 0.23 12.1 0.6 1.3 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region PHM7_cyt PF14703.6 VBB28153.1 - 0.29 11.4 6.7 0.61 10.3 6.7 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Rx_N PF18052.1 VBB28153.1 - 0.55 10.5 5.4 0.16 12.2 1.2 2.0 1 1 1 2 2 2 0 Rx N-terminal domain KIP1 PF07765.12 VBB28153.1 - 0.91 9.7 6.8 4.5 7.5 1.3 2.2 2 0 0 2 2 2 0 KIP1-like protein DUF1664 PF07889.12 VBB28153.1 - 3 7.9 7.5 0.33 11.0 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MRPL52 PF18699.1 VBB28153.1 - 7.2 6.9 10.3 0.57 10.4 3.1 2.1 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Fib_alpha PF08702.10 VBB28153.1 - 8.3 6.6 11.7 95 3.2 11.9 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SAE2 PF08573.10 VBB28154.1 - 6.1e-07 30.5 7.1 0.00021 22.4 0.1 3.3 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Leptin PF02024.15 VBB28154.1 - 0.04 13.7 0.9 0.084 12.6 0.9 1.6 1 0 0 1 1 1 0 Leptin INTS2 PF14750.6 VBB28155.1 - 4.1e-268 892.1 35.2 4.9e-268 891.9 35.2 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 ELO PF01151.18 VBB28156.1 - 2.1e-32 112.6 11.8 2.4e-32 112.4 11.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Phage_holin_Dp1 PF16938.5 VBB28156.1 - 0.16 12.2 3.3 1.1 9.6 0.1 3.0 3 0 0 3 3 3 0 Putative phage holin Dp-1 DUF5337 PF17272.2 VBB28156.1 - 0.3 10.9 9.2 0.53 10.1 2.2 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5337) HEAT_2 PF13646.6 VBB28158.1 - 5.1e-05 23.6 0.4 1.7 9.1 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats Arm PF00514.23 VBB28158.1 - 0.0004 20.3 0.0 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 VBB28158.1 - 0.015 15.5 4.2 1.5 9.3 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 VBB28158.1 - 0.032 14.3 14.6 0.11 12.5 0.7 4.8 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 VBB28158.1 - 0.035 14.7 2.2 9.8 6.8 0.1 4.3 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region CENP-X PF09415.10 VBB28158.1 - 0.071 13.4 0.0 0.37 11.1 0.0 2.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X HEAT_EZ PF13513.6 VBB28158.1 - 0.16 12.5 0.0 2.7 8.6 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat His_Phos_1 PF00300.22 VBB28160.1 - 6.6e-19 68.4 0.0 9.3e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lectin_C PF00059.21 VBB28161.1 - 1.2e-11 45.2 5.9 3.6e-09 37.3 0.3 3.2 3 1 0 3 3 3 2 Lectin C-type domain DBR1 PF05011.13 VBB28162.1 - 3.3e-35 121.5 0.1 5.6e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 VBB28162.1 - 8.8e-07 29.6 0.6 1.7e-06 28.7 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Rhodanese PF00581.20 VBB28163.1 - 8.3e-14 52.0 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Syntaxin_2 PF14523.6 VBB28164.1 - 0.024 15.0 3.5 3.9 7.9 0.0 3.0 2 0 0 2 2 2 0 Syntaxin-like protein UvrA_inter PF17760.1 VBB28164.1 - 0.024 14.7 1.4 0.075 13.1 1.4 1.8 1 0 0 1 1 1 0 UvrA interaction domain Phage_BR0599 PF09356.10 VBB28164.1 - 0.077 13.3 0.1 0.63 10.4 0.0 2.5 2 0 0 2 2 2 0 Phage conserved hypothetical protein BR0599 TLE_N PF03920.15 VBB28164.1 - 0.31 11.1 4.6 0.33 11.0 1.6 2.2 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF4315 PF14193.6 VBB28164.1 - 0.68 10.0 5.2 2.3 8.3 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) Rhodanese PF00581.20 VBB28165.1 - 3.9e-10 40.2 0.0 1.4e-08 35.2 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain WD40 PF00400.32 VBB28166.1 - 4.7e-50 166.5 32.2 1.1e-08 35.6 0.3 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28166.1 - 3.5e-13 49.6 6.1 0.45 10.9 0.1 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 VBB28166.1 - 1.6e-12 47.1 0.5 3.4e-12 46.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB28166.1 - 1.6e-09 37.4 0.5 3.2e-09 36.4 0.5 1.6 1 0 0 1 1 1 1 F-box domain Ge1_WD40 PF16529.5 VBB28166.1 - 5.4e-08 32.2 10.2 0.038 13.0 0.2 5.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 VBB28166.1 - 3.9e-07 29.1 14.2 0.24 10.0 0.3 6.1 2 2 4 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB28166.1 - 0.0052 16.2 1.5 0.12 11.7 0.0 3.0 3 1 0 4 4 4 1 WD40-like domain Globin PF00042.22 VBB28167.1 - 1.5e-07 31.9 0.1 2.8e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Globin DUF3678 PF12435.8 VBB28167.1 - 0.48 9.8 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Y_phosphatase PF00102.27 VBB28168.1 - 6.9e-76 254.9 0.2 9.3e-76 254.5 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 VBB28168.1 - 2.1e-20 72.9 0.0 4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 VBB28168.1 - 4.6e-05 23.5 0.0 6.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PDZ_6 PF17820.1 VBB28168.1 - 0.00018 21.2 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 VBB28168.1 - 0.00064 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB28168.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PDZ_2 PF13180.6 VBB28168.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain APP_amyloid PF10515.9 VBB28168.1 - 2.5 8.6 4.8 1.1 9.8 0.2 2.4 2 0 0 2 2 2 0 Beta-amyloid precursor protein C-terminus Pkinase PF00069.25 VBB28169.1 - 1.4e-61 208.1 0.0 2.5e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28169.1 - 5.3e-45 153.7 0.0 8.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 VBB28169.1 - 2.9e-17 62.9 4.4 4.9e-16 58.9 3.8 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 VBB28169.1 - 8e-05 22.1 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB28169.1 - 0.00017 21.0 0.0 0.00037 19.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB28169.1 - 0.0093 14.8 0.1 0.049 12.4 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase RIO1 PF01163.22 VBB28169.1 - 0.0096 15.5 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Abi_HHR PF07815.14 VBB28170.1 - 2.1e-26 91.9 0.1 4.7e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.6 VBB28170.1 - 1.7e-16 59.8 0.3 3.1e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB28170.1 - 1.3e-13 50.3 0.0 2.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB28170.1 - 7.5e-10 38.4 0.0 1.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain MetW PF07021.12 VBB28170.1 - 0.12 11.9 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW LicD PF04991.13 VBB28171.1 - 0.0021 18.2 2.3 0.023 14.8 0.6 2.9 2 1 0 3 3 3 1 LicD family DUF3519 PF12033.8 VBB28171.1 - 0.043 14.2 0.3 0.52 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3519) SelR PF01641.18 VBB28172.1 - 3.5e-52 175.6 1.6 4.1e-52 175.4 1.6 1.0 1 0 0 1 1 1 1 SelR domain Ribosomal_L37e PF01907.19 VBB28172.1 - 0.0042 17.2 5.0 0.022 14.9 1.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L37e Yippee-Mis18 PF03226.14 VBB28172.1 - 0.0046 17.2 5.3 0.0076 16.4 5.3 1.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_SprT PF17283.2 VBB28172.1 - 0.0056 16.6 0.7 1.9 8.5 0.1 2.3 2 0 0 2 2 2 2 SprT-like zinc ribbon domain HECT_2 PF09814.9 VBB28172.1 - 0.27 10.0 4.0 0.39 9.5 0.3 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_10 PF10058.9 VBB28172.1 - 0.48 10.2 6.5 0.42 10.4 1.4 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RRN7 PF11781.8 VBB28172.1 - 5.6 6.7 11.2 3 7.6 2.1 2.9 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SMAP PF15477.6 VBB28173.1 - 3.4e-15 56.7 0.6 3.4e-15 56.7 0.6 3.0 3 1 0 3 3 3 1 Small acidic protein family ITAM PF02189.15 VBB28173.1 - 4.3 8.0 6.4 24 5.7 0.3 3.0 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif CRAL_TRIO PF00650.20 VBB28174.1 - 1.2e-20 73.9 0.0 1.9e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.26 VBB28174.1 - 1.9e-15 56.6 0.0 6.2e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.6 VBB28174.1 - 9.9e-05 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PapD-like PF14874.6 VBB28174.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like Peptidase_M41 PF01434.18 VBB28175.1 - 1.8e-65 220.4 0.9 2.8e-65 219.7 0.9 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 VBB28175.1 - 5.1e-20 72.2 0.3 4.6e-19 69.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB28175.1 - 1.4e-09 37.5 0.2 3.5e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain DUF5069 PF16798.5 VBB28175.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) ALMT PF11744.8 VBB28175.1 - 0.3 9.9 1.1 0.44 9.3 1.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 VBB28176.1 - 3.1e-61 207.0 0.0 5e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28176.1 - 2.4e-32 112.3 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB28176.1 - 5.1e-06 26.0 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB28176.1 - 4e-05 22.6 0.1 6.6e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB28176.1 - 0.0032 16.9 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB28176.1 - 0.0075 16.2 0.4 0.014 15.4 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Myb_DNA-bind_4 PF13837.6 VBB28177.1 - 0.11 12.9 0.8 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HAGH_C PF16123.5 VBB28178.1 - 9.7e-18 64.5 0.1 2.1e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 VBB28178.1 - 3e-15 56.8 0.0 9.6e-15 55.1 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB28178.1 - 9.2e-05 22.0 0.1 0.00026 20.6 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 VBB28178.1 - 0.052 13.4 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain RR_TM4-6 PF06459.12 VBB28179.1 - 0.0044 16.9 18.1 0.0048 16.8 18.1 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 VBB28179.1 - 0.026 13.0 11.2 0.032 12.7 11.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Pal1 PF08316.11 VBB28179.1 - 0.044 14.5 7.6 0.064 14.0 7.6 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Vfa1 PF08432.10 VBB28179.1 - 0.069 13.5 21.7 0.087 13.1 21.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AF-4 PF05110.13 VBB28179.1 - 0.076 11.1 20.0 0.086 10.9 20.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_11 PF13086.6 VBB28179.1 - 0.15 11.8 9.3 0.16 11.7 9.3 1.1 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 VBB28179.1 - 0.19 10.5 12.9 0.21 10.3 12.9 1.1 1 0 0 1 1 1 0 Presenilin U79_P34 PF03064.16 VBB28179.1 - 0.51 9.7 20.9 0.8 9.0 20.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PPL5 PF18168.1 VBB28179.1 - 0.51 9.6 8.6 0.6 9.4 8.6 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Borrelia_P83 PF05262.11 VBB28179.1 - 0.54 8.7 20.0 0.58 8.6 20.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Zip PF02535.22 VBB28179.1 - 0.59 9.3 7.8 0.62 9.2 7.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 VBB28179.1 - 0.73 10.0 7.1 0.8 9.8 7.1 1.2 1 0 0 1 1 1 0 DDHD domain TRAP_alpha PF03896.16 VBB28179.1 - 0.75 9.0 7.7 1 8.5 7.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SLC12 PF03522.15 VBB28179.1 - 0.8 8.7 11.3 0.84 8.6 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Paf1 PF03985.13 VBB28179.1 - 1.1 8.2 22.3 1.4 7.9 22.3 1.2 1 0 0 1 1 1 0 Paf1 DUF2828 PF11443.8 VBB28179.1 - 1.9 6.5 13.9 2.3 6.2 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NARP1 PF12569.8 VBB28179.1 - 2 7.2 24.1 2.6 6.9 24.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.7 VBB28179.1 - 2 6.4 9.6 2 6.5 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 VBB28179.1 - 2.1 7.0 12.3 2.4 6.9 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 VBB28179.1 - 2.1 8.3 8.7 2.3 8.2 8.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 VBB28179.1 - 2.2 8.0 12.2 3.5 7.3 12.2 1.4 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 VBB28179.1 - 2.3 6.9 16.0 3.1 6.5 16.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 VBB28179.1 - 2.8 6.9 9.0 3.1 6.7 9.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 VBB28179.1 - 2.8 6.1 18.3 2.9 6.1 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 VBB28179.1 - 2.9 6.7 8.2 3.1 6.6 8.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein O-antigen_lig PF13425.6 VBB28179.1 - 2.9 6.6 7.9 3.3 6.4 7.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 VBB28179.1 - 4 6.4 6.6 4.8 6.1 6.6 1.1 1 0 0 1 1 1 0 CLN3 protein PA26 PF04636.13 VBB28179.1 - 6.6 5.5 10.2 7.9 5.3 10.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNA_polI_A34 PF08208.11 VBB28179.1 - 6.9 6.7 32.4 13 5.8 32.3 1.7 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ALMT PF11744.8 VBB28179.1 - 8.2 5.1 9.0 9.1 5.0 9.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RasGAP PF00616.19 VBB28179.1 - 9.9 5.8 11.9 14 5.3 11.9 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase BTB PF00651.31 VBB28180.1 - 4.9e-26 91.1 0.2 1.5e-25 89.6 0.1 1.8 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 VBB28180.1 - 0.00091 19.3 0.2 0.014 15.5 0.1 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch Exo_endo_phos PF03372.23 VBB28181.1 - 1.9e-07 30.9 0.0 4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SKICH PF17751.1 VBB28181.1 - 3.6e-07 30.7 0.6 7.7e-07 29.6 0.6 1.6 1 0 0 1 1 1 1 SKICH domain DUF3335 PF11814.8 VBB28181.1 - 0.059 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family zf-C4 PF00105.18 VBB28183.1 - 1e-23 83.6 16.3 1.1e-23 83.4 14.3 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 VBB28183.1 - 0.0032 17.5 7.8 0.0032 17.5 7.8 1.8 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type DNA_repr_REX1B PF14966.6 VBB28183.1 - 0.033 14.9 0.1 0.094 13.4 0.1 1.8 1 0 0 1 1 1 0 DNA repair REX1-B MATH PF00917.26 VBB28184.1 - 2.3e-13 50.3 0.1 2.3e-13 50.3 0.1 2.8 2 0 0 2 2 2 1 MATH domain DUF812 PF05667.11 VBB28184.1 - 0.00017 20.7 33.5 0.00017 20.7 33.5 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF812) DUF4211 PF13926.6 VBB28185.1 - 2.8e-08 33.9 0.0 8.8e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Aldo_ket_red PF00248.21 VBB28186.1 - 2.1e-47 161.7 0.2 1.2e-45 155.9 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family N_BRCA1_IG PF16158.5 VBB28187.1 - 5.4e-32 110.6 0.5 1.1e-31 109.6 0.5 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 VBB28187.1 - 1.5e-10 40.7 0.5 2.8e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain CARDB PF07705.11 VBB28187.1 - 0.0044 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 CARDB DUF1508 PF07411.12 VBB28188.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) DHHA1 PF02272.19 VBB28188.1 - 6.4 7.2 7.5 1.8 9.0 0.1 3.2 3 0 0 3 3 3 0 DHHA1 domain ATG11 PF10377.9 VBB28189.1 - 5.4e-07 29.7 0.1 6e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 11 7tm_1 PF00001.21 VBB28190.1 - 4.4e-50 170.4 0.0 7.3e-50 169.7 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB28190.1 - 6.1e-07 29.3 3.9 6.1e-07 29.3 3.9 2.4 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 VBB28190.1 - 2.4e-06 27.2 10.3 9.5e-06 25.2 2.2 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Homeodomain PF00046.29 VBB28192.1 - 1.5e-21 76.0 3.1 3.4e-21 74.8 3.1 1.6 1 0 0 1 1 1 1 Homeodomain MOR2-PAG1_mid PF14228.6 VBB28192.1 - 0.04 11.6 0.5 0.048 11.3 0.5 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region Homeobox_KN PF05920.11 VBB28192.1 - 0.069 13.1 1.2 0.097 12.6 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain RRM_1 PF00076.22 VBB28194.1 - 7.8e-10 38.4 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 VBB28195.1 - 3.2e-09 36.8 17.7 7.3e-07 29.2 5.0 4.5 4 1 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 VBB28195.1 - 7.1e-06 26.0 0.7 7.1e-06 26.0 0.7 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB28195.1 - 7.7e-05 22.5 0.9 7.7e-05 22.5 0.9 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB28195.1 - 0.0012 18.7 1.7 0.0012 18.7 1.7 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB28195.1 - 0.0025 17.6 1.3 0.0025 17.6 1.3 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB28195.1 - 0.0069 16.5 1.4 0.0069 16.5 1.4 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 VBB28195.1 - 0.014 15.4 7.9 0.014 15.4 7.9 4.2 4 1 0 4 4 4 0 zinc-RING finger domain Baculo_PEP_C PF04513.12 VBB28195.1 - 0.055 13.5 5.5 0.11 12.5 0.5 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M16_C PF05193.21 VBB28196.1 - 4.5e-23 82.2 0.2 9.9e-13 48.5 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 VBB28196.1 - 3.5e-11 43.3 1.5 1.1e-10 41.7 0.0 2.5 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) ATP-cone PF03477.16 VBB28196.1 - 0.14 12.7 0.3 0.96 10.1 0.1 2.5 3 0 0 3 3 3 0 ATP cone domain Tfb5 PF06331.12 VBB28197.1 - 5.1e-25 87.2 0.5 6.8e-25 86.8 0.5 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 RNase_H PF00075.24 VBB28198.1 - 2.1e-22 79.9 0.3 5.2e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 VBB28198.1 - 0.00041 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Glyco_hydro_97 PF10566.9 VBB28198.1 - 0.11 11.7 1.4 0.19 11.0 1.4 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 PspB PF06667.12 VBB28198.1 - 0.73 9.9 2.7 1.5 8.9 0.4 2.2 2 0 0 2 2 2 0 Phage shock protein B ERK-JNK_inhib PF15002.6 VBB28199.1 - 1.9e-54 184.3 4.5 3.6e-54 183.4 4.5 1.4 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor zf-AN1 PF01428.16 VBB28199.1 - 5.9e-09 35.9 11.6 5.9e-09 35.9 11.6 3.9 3 1 0 3 3 3 1 AN1-like Zinc finger DUF1804 PF08822.11 VBB28199.1 - 0.057 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Zip PF02535.22 VBB28199.1 - 7.5 5.7 8.8 20 4.3 8.8 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter EGF_CA PF07645.15 VBB28201.1 - 3.1e-12 46.5 43.3 1e-07 32.0 1.1 5.2 4 1 1 5 5 5 3 Calcium-binding EGF domain EGF PF00008.27 VBB28201.1 - 4e-09 36.6 45.7 0.00022 21.5 1.8 5.5 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.7 VBB28201.1 - 4.8e-06 27.0 41.4 0.0028 18.2 1.0 6.0 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_3 PF12947.7 VBB28201.1 - 3.8e-05 23.8 50.5 0.012 15.8 0.8 4.9 5 0 0 5 5 5 4 EGF domain FXa_inhibition PF14670.6 VBB28201.1 - 0.0019 18.4 40.3 0.0074 16.5 1.0 5.5 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 VBB28201.1 - 0.13 12.6 42.8 0.089 13.1 2.9 4.7 4 0 0 4 4 4 0 Pvs28 EGF domain cEGF PF12662.7 VBB28201.1 - 2.3 8.3 29.5 0.062 13.2 1.3 6.3 5 1 0 5 5 5 0 Complement Clr-like EGF-like Coatomer_WDAD PF04053.14 VBB28203.1 - 7.6e-162 539.4 0.0 2.9e-160 534.2 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 VBB28203.1 - 2.3e-37 126.3 14.0 2.1e-07 31.5 0.1 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28203.1 - 2.3e-07 31.0 2.6 0.48 10.8 0.0 5.4 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 VBB28203.1 - 0.00055 19.9 0.1 1.4 9.0 0.0 4.4 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 VBB28203.1 - 0.018 15.3 0.4 0.072 13.3 0.2 2.1 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase FYVE PF01363.21 VBB28204.1 - 2.9e-19 68.9 11.2 5.2e-19 68.1 11.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 VBB28204.1 - 6e-08 33.2 0.1 1e-07 32.4 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 VBB28204.1 - 0.0017 18.5 5.6 0.0035 17.6 5.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 VBB28204.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 PH domain zf-SNAP50_C PF12251.8 VBB28204.1 - 1.7 8.3 8.4 0.82 9.3 4.7 2.2 2 1 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal HSP20 PF00011.21 VBB28205.1 - 3.1e-16 59.4 0.0 4.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB28205.1 - 0.00091 18.7 0.0 0.0023 17.5 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF3984 PF13136.6 VBB28205.1 - 0.038 13.4 0.4 0.038 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) 7tm_3 PF00003.22 VBB28206.1 - 9e-36 123.8 21.5 1.6e-35 122.9 21.5 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 VBB28206.1 - 7.3e-20 71.4 0.8 4.2e-13 49.1 0.0 2.7 3 0 0 3 3 3 2 Receptor family ligand binding region Alg14 PF08660.11 VBB28206.1 - 4.5e-05 23.5 0.0 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like DUF2815 PF10991.8 VBB28206.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) PSS PF03034.15 VBB28207.1 - 1.3e-53 182.6 9.0 1.8e-53 182.1 9.0 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase TNFR_16_TM PF18422.1 VBB28207.1 - 0.24 11.4 0.2 0.24 11.4 0.2 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain RRM_1 PF00076.22 VBB28208.1 - 7.1e-20 70.6 0.0 1.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB28208.1 - 1.3e-05 25.2 0.0 3.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB28208.1 - 0.00039 20.4 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 VBB28208.1 - 0.04 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 VBB28208.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1314 PF07013.11 VBB28208.1 - 0.072 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Collagen PF01391.18 VBB28209.1 - 1.7e-227 735.5 795.0 3.3e-10 39.6 21.2 29.9 2 2 26 28 28 28 28 Collagen triple helix repeat (20 copies) C4 PF01413.19 VBB28209.1 - 7.4e-62 206.6 3.7 2.8e-44 150.0 0.3 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COesterase PF00135.28 VBB28210.1 - 1.3e-148 496.0 0.0 1.6e-148 495.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB28210.1 - 9e-06 25.7 0.0 3.3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold AChE_tetra PF08674.10 VBB28210.1 - 0.0022 17.7 7.2 0.0062 16.2 7.2 1.7 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain Yippee-Mis18 PF03226.14 VBB28211.1 - 1.6e-05 25.0 0.1 2.5e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_2 PF13240.6 VBB28211.1 - 0.023 14.4 2.3 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain LisH PF08513.11 VBB28211.1 - 0.048 13.6 0.2 0.097 12.7 0.2 1.5 1 0 0 1 1 1 0 LisH zinc_ribbon_4 PF13717.6 VBB28211.1 - 0.88 9.6 3.7 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.8 VBB28211.1 - 1.7 8.1 4.2 5.2 6.6 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2688) TPR_14 PF13428.6 VBB28212.1 - 4.7e-19 67.5 10.4 0.033 15.0 0.1 12.0 7 3 5 12 12 11 3 Tetratricopeptide repeat Suf PF05843.14 VBB28212.1 - 4.3e-10 40.1 20.5 0.0038 17.3 1.2 5.9 4 1 3 7 7 7 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 VBB28212.1 - 9.1e-09 34.9 16.4 0.54 10.6 0.2 9.0 9 0 0 9 9 8 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 VBB28212.1 - 2.6e-08 33.9 18.3 0.003 17.5 0.5 6.6 4 4 2 6 6 6 3 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 VBB28212.1 - 3.1e-08 33.1 13.5 0.0038 17.2 0.4 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB28212.1 - 4.8e-07 30.0 8.6 0.56 10.5 0.2 6.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB28212.1 - 8.8e-07 28.4 5.1 0.23 10.6 0.0 6.1 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB28212.1 - 5.4e-05 23.6 6.2 4.7 7.8 0.0 7.6 9 1 1 10 10 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB28212.1 - 5.8e-05 23.7 3.2 0.69 10.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 VBB28212.1 - 6.1e-05 22.3 9.9 0.0003 20.0 0.4 4.8 2 2 0 3 3 3 1 NRDE-2, necessary for RNA interference RPN7 PF10602.9 VBB28212.1 - 0.00028 20.7 2.5 0.54 9.9 0.0 3.6 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_17 PF13431.6 VBB28212.1 - 0.00051 20.2 9.2 3.2 8.3 0.1 7.2 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB28212.1 - 0.004 17.1 4.9 0.034 14.2 0.1 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat SNAP PF14938.6 VBB28212.1 - 0.014 14.8 8.8 1.2 8.5 0.1 4.3 3 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 VBB28212.1 - 0.044 14.0 0.3 16 5.8 0.0 3.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Bacteroid_pep PF14406.6 VBB28212.1 - 0.082 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes TPR_10 PF13374.6 VBB28212.1 - 0.11 12.4 6.2 5.9 6.9 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 VBB28212.1 - 0.13 12.6 1.9 17 5.9 0.0 4.3 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 VBB28212.1 - 0.43 11.3 11.1 39 5.2 0.0 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat RasGAP PF00616.19 VBB28212.1 - 0.59 9.8 3.0 0.7 9.6 1.4 1.9 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase TPR_4 PF07721.14 VBB28212.1 - 3.3 8.6 8.3 0.36 11.6 0.4 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB28212.1 - 4 7.4 11.8 2.4 8.1 0.3 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Metallophos PF00149.28 VBB28213.1 - 5.5e-35 121.7 0.0 6.8e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB28213.1 - 0.0022 18.2 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CENP-B_dimeris PF09026.10 VBB28214.1 - 0.0095 16.3 8.5 0.0099 16.2 8.5 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 VBB28214.1 - 0.3 11.0 4.2 0.32 10.8 4.2 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 VBB28214.1 - 0.41 10.3 3.6 0.51 10.0 3.6 1.1 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 VBB28214.1 - 2.7 6.0 11.6 2.6 6.0 11.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 VBB28214.1 - 3.5 6.6 15.9 4.3 6.4 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ion_trans_2 PF07885.16 VBB28215.1 - 5.3e-25 87.2 16.7 2.1e-14 53.3 0.4 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB28215.1 - 0.047 12.9 11.2 0.11 11.7 0.2 2.2 2 0 0 2 2 2 0 Ion transport protein IRK PF01007.20 VBB28215.1 - 0.16 11.8 1.2 0.74 9.6 0.2 2.4 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain DUF1700 PF08006.11 VBB28215.1 - 8.3 5.9 7.8 4.3 6.8 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1700) NTF2 PF02136.20 VBB28216.1 - 1.2e-17 64.6 0.1 1.4e-17 64.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 VBB28216.1 - 0.0017 18.3 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Phage_Coat_Gp8 PF05371.12 VBB28216.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Phage major coat protein, Gp8 AdoHcyase PF05221.17 VBB28217.1 - 9.3e-126 419.0 0.0 2e-64 217.6 0.4 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 VBB28217.1 - 1.9e-81 271.9 2.2 2.9e-81 271.3 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 VBB28217.1 - 7e-07 28.8 0.1 1.2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 VBB28217.1 - 0.00011 21.8 0.6 0.0002 20.9 0.6 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 VBB28217.1 - 0.0029 17.9 0.1 0.006 16.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 VBB28217.1 - 0.034 13.9 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 VBB28217.1 - 0.087 13.3 0.2 0.37 11.2 0.5 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding CutA1 PF03091.15 VBB28217.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Cpn60_TCP1 PF00118.24 VBB28218.1 - 1e-150 502.6 9.6 1.2e-150 502.4 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Alanine_zipper PF11839.8 VBB28219.1 - 0.17 12.3 11.0 0.27 11.6 11.0 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DDA1 PF10172.9 VBB28220.1 - 1.5e-07 31.6 2.4 1.6e-07 31.5 0.3 2.1 2 1 0 2 2 2 1 Det1 complexing ubiquitin ligase CIAPIN1 PF05093.13 VBB28221.1 - 1e-21 77.3 11.7 1.1e-16 61.1 3.8 2.4 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis V-SNARE PF05008.15 VBB28222.1 - 0.017 15.5 4.5 0.017 15.5 4.5 3.1 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4525 PF15027.6 VBB28222.1 - 0.042 13.6 0.8 0.079 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) MUG113 PF13455.6 VBB28222.1 - 0.084 13.6 0.3 0.18 12.5 0.3 1.5 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 DUF1664 PF07889.12 VBB28222.1 - 0.27 11.3 3.6 3.7 7.6 0.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 VBB28222.1 - 0.35 11.2 12.9 1.4 9.2 0.6 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 Fez1 PF06818.15 VBB28222.1 - 1.7 9.0 20.8 0.32 11.4 6.3 2.3 1 1 1 2 2 2 0 Fez1 DUF3385 PF11865.8 VBB28223.1 - 2.6e-47 160.7 8.1 9.4e-46 155.7 0.1 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 VBB28223.1 - 3.2e-11 43.5 1.7 0.15 12.5 0.0 7.1 4 2 2 7 7 7 3 HEAT repeats HEAT PF02985.22 VBB28223.1 - 6.7e-07 29.0 7.5 1.3 9.5 0.0 7.5 6 0 0 6 6 6 2 HEAT repeat API5 PF05918.11 VBB28223.1 - 0.031 13.1 0.8 0.075 11.8 0.3 1.9 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.6 VBB28223.1 - 0.046 14.3 13.0 49 4.6 0.0 8.5 10 0 0 10 10 10 0 HEAT-like repeat TIP120 PF08623.10 VBB28223.1 - 0.22 11.3 1.7 8.1 6.2 0.0 3.9 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) V-ATPase_H_N PF03224.14 VBB28223.1 - 0.55 9.5 12.9 0.12 11.7 0.2 3.7 3 1 1 4 4 4 0 V-ATPase subunit H Cupin_4 PF08007.12 VBB28224.1 - 3.3e-54 184.5 0.0 5.8e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 VBB28224.1 - 0.00053 19.8 8.0 0.0065 16.2 7.0 3.1 1 1 0 1 1 1 1 Cupin-like domain Endonuc_subdom PF09062.10 VBB28224.1 - 0.034 15.0 0.1 0.2 12.5 0.1 2.4 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain Cupin_1 PF00190.22 VBB28224.1 - 0.039 13.6 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin Hamartin PF04388.12 VBB28224.1 - 8.3 4.9 8.4 12 4.4 8.4 1.2 1 0 0 1 1 1 0 Hamartin protein Methyltransf_3 PF01596.17 VBB28225.1 - 3.2e-36 124.5 0.0 4.9e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PLDc_3 PF13918.6 VBB28225.1 - 7.2e-35 120.2 0.1 1.3e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 VBB28225.1 - 1.6e-24 86.3 0.9 1.7e-12 47.4 0.0 2.9 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 VBB28225.1 - 6.8e-16 57.7 2.7 4.6e-09 36.1 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Methyltransf_24 PF13578.6 VBB28225.1 - 2.9e-07 31.5 0.0 1.3e-06 29.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain F-box PF00646.33 VBB28226.1 - 6.8e-12 45.0 2.5 9e-12 44.6 0.7 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 VBB28226.1 - 1.1e-09 38.0 0.3 1.1e-09 38.0 0.3 2.8 3 0 0 3 3 3 1 F-box-like Spt20 PF12090.8 VBB28226.1 - 0.02 14.5 4.5 0.037 13.6 4.5 1.5 1 0 0 1 1 1 0 Spt20 family PRANC PF09372.10 VBB28226.1 - 0.026 14.8 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 PRANC domain DUF4834 PF16118.5 VBB28226.1 - 0.033 15.1 0.5 0.073 14.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5336 PF17270.2 VBB28226.1 - 0.12 12.0 0.4 0.2 11.3 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Pkinase PF00069.25 VBB28227.1 - 1.4e-62 211.4 0.3 1.6e-62 211.3 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28227.1 - 6.3e-34 117.4 0.1 7e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB28227.1 - 2.5e-06 27.0 0.8 0.03 13.7 0.0 2.8 1 1 2 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 VBB28227.1 - 2.9e-06 26.5 1.1 2.1e-05 23.6 1.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB28227.1 - 0.023 14.6 1.0 0.077 12.9 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 VBB28227.1 - 0.031 13.3 0.5 0.043 12.8 0.5 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DEAD PF00270.29 VBB28228.1 - 3.9e-34 117.9 0.0 6.1e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB28228.1 - 3.1e-29 101.6 0.4 9.9e-29 99.9 0.4 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB28228.1 - 0.00028 20.9 0.0 0.0011 19.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Proteasome PF00227.26 VBB28229.1 - 7.6e-36 123.4 0.0 9.1e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Sad1_UNC PF07738.13 VBB28230.1 - 4.3e-28 97.9 0.0 9.1e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal M_domain PF12938.7 VBB28231.1 - 0.021 14.6 0.1 0.021 14.6 0.1 2.7 3 0 0 3 3 3 0 M domain of GW182 DUF1005 PF06219.12 VBB28232.1 - 0.019 14.0 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) WD40 PF00400.32 VBB28233.1 - 5e-36 122.1 23.1 9.8e-07 29.4 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 VBB28233.1 - 5.1e-18 64.7 0.3 1.3e-17 63.4 0.3 1.7 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 VBB28233.1 - 9.9e-09 35.4 0.8 0.0019 18.5 0.1 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 VBB28233.1 - 1.6e-06 27.9 1.2 3.2e-06 26.9 1.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 VBB28233.1 - 4.7e-05 22.3 7.7 0.027 13.1 0.2 4.2 2 2 2 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB28233.1 - 7.6e-05 22.2 0.1 0.0083 15.5 0.1 2.7 1 1 2 3 3 3 3 WD40-like domain F-box PF00646.33 VBB28233.1 - 0.0091 15.9 1.1 0.03 14.2 1.1 1.9 1 0 0 1 1 1 1 F-box domain 120_Rick_ant PF12574.8 VBB28233.1 - 0.16 11.2 0.0 0.64 9.2 0.0 1.8 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen RHH_1 PF01402.21 VBB28234.1 - 0.099 12.6 0.9 0.25 11.3 0.7 1.8 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family tRNA_int_endo PF01974.17 VBB28235.1 - 2.4e-22 78.8 0.0 6.8e-21 74.1 0.0 2.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain LSM PF01423.22 VBB28235.1 - 1.6e-15 56.5 0.1 2.8e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 VBB28235.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain DnaB_C PF03796.15 VBB28236.1 - 5.2e-15 55.5 0.1 3.2e-14 52.9 0.0 2.4 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 VBB28236.1 - 5.5e-14 52.2 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 VBB28236.1 - 1e-06 28.3 0.4 2.6e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 KaiC AAA_22 PF13401.6 VBB28236.1 - 0.0037 17.5 1.1 0.015 15.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 VBB28236.1 - 0.017 14.2 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 VBB28236.1 - 0.035 13.8 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 VBB28236.1 - 0.045 14.3 0.0 0.045 14.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 VBB28236.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 VBB28236.1 - 0.059 13.4 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zn_Tnp_IS91 PF14319.6 VBB28236.1 - 0.12 12.4 0.5 0.32 11.1 0.5 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain GSHPx PF00255.19 VBB28237.1 - 1.8e-40 136.8 1.8 2.6e-40 136.3 0.2 2.1 3 0 0 3 3 3 1 Glutathione peroxidase AhpC-TSA PF00578.21 VBB28237.1 - 0.0002 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB28237.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Redoxin Sulfate_transp PF00916.20 VBB28238.1 - 2.2e-91 306.5 27.9 2.8e-91 306.1 27.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 VBB28238.1 - 3.7e-20 71.7 0.1 6.9e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 STAS domain Taxilin PF09728.9 VBB28239.1 - 2.2e-66 224.1 61.2 2.8e-66 223.8 61.2 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Cortex-I_coil PF09304.10 VBB28239.1 - 0.013 15.7 6.2 0.013 15.7 6.2 4.5 1 1 1 3 3 3 0 Cortexillin I, coiled coil LOH1CR12 PF10158.9 VBB28239.1 - 0.042 13.9 23.1 0.044 13.8 0.6 4.4 1 1 3 4 4 4 0 Tumour suppressor protein Ubiquitin_3 PF14836.6 VBB28239.1 - 0.11 12.5 0.3 0.11 12.5 0.3 3.0 2 1 0 3 3 3 0 Ubiquitin-like domain DUF3037 PF11236.8 VBB28239.1 - 0.46 10.9 16.0 0.78 10.2 2.3 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF3037) DUF3584 PF12128.8 VBB28239.1 - 0.51 7.8 43.2 4.6 4.6 42.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 VBB28239.1 - 0.85 9.7 49.8 0.23 11.5 15.5 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 VBB28239.1 - 1.6 7.6 54.1 0.019 13.8 17.4 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein HOOK PF05622.12 VBB28239.1 - 1.7 6.7 51.8 0.95 7.5 17.5 2.8 1 1 1 2 2 2 0 HOOK protein COMM_domain PF07258.14 VBB28239.1 - 3.1 8.0 12.4 7 6.9 0.7 4.1 4 0 0 4 4 4 0 COMM domain IFT57 PF10498.9 VBB28239.1 - 4.3 6.2 40.3 4.9 6.0 19.9 3.0 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 OPA3 PF07047.12 VBB28242.1 - 3.5e-20 72.0 0.4 5.1e-20 71.5 0.4 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF5305 PF17231.2 VBB28242.1 - 0.0064 15.9 1.3 0.0087 15.5 1.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Tim29 PF10171.9 VBB28242.1 - 0.071 12.6 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Herpes_UL92 PF03048.14 VBB28242.1 - 0.11 12.3 0.3 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 UL92 family DUF2408 PF10303.9 VBB28242.1 - 0.11 13.1 2.1 0.17 12.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Ribonuc_red_lgC PF02867.15 VBB28243.1 - 2.3e-191 636.9 0.0 3.1e-191 636.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 VBB28243.1 - 8e-24 83.5 0.0 2.3e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 VBB28243.1 - 1.9e-17 63.6 2.0 1.9e-17 63.6 0.2 2.0 2 0 0 2 2 2 1 ATP cone domain NCBP3 PF10309.9 VBB28244.1 - 2.1e-08 33.9 0.1 3.8e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Pap_E4 PF02711.14 VBB28244.1 - 0.86 10.6 9.8 1.8 9.6 2.7 2.8 2 0 0 2 2 2 0 E4 protein SP_C-Propep PF08999.10 VBB28245.1 - 0.042 13.6 1.1 0.057 13.2 1.1 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Pga1 PF10333.9 VBB28245.1 - 0.061 13.2 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Josephin PF02099.17 VBB28246.1 - 6.7e-45 153.1 0.0 6.7e-45 153.1 0.0 2.4 2 1 0 2 2 2 1 Josephin UIM PF02809.20 VBB28246.1 - 0.071 13.1 0.7 0.071 13.1 0.7 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif PI-PLC-X PF00388.19 VBB28247.1 - 1.8e-38 131.3 0.0 3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 VBB28247.1 - 4.7e-29 101.1 0.0 1.1e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 VBB28247.1 - 0.048 14.1 0.0 0.19 12.3 0.0 2.0 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Annexin PF00191.20 VBB28248.1 - 1.1e-90 297.6 12.7 6.8e-24 83.7 0.3 4.0 4 0 0 4 4 4 4 Annexin DUF3924 PF13062.6 VBB28248.1 - 0.015 15.2 2.9 4.7 7.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3924) OST-HTH PF12872.7 VBB28248.1 - 0.074 12.9 2.3 4.2 7.3 0.1 4.1 5 0 0 5 5 5 0 OST-HTH/LOTUS domain TERT_thumb PF17984.1 VBB28248.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain FeoB_Cyto PF17910.1 VBB28248.1 - 0.22 12.1 5.2 12 6.6 0.2 3.9 2 1 2 4 4 4 0 FeoB cytosolic helical domain Rubis-subs-bind PF09273.11 VBB28250.1 - 4e-06 27.5 0.0 7.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 VBB28250.1 - 0.00021 21.8 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 SET domain Lectin_C PF00059.21 VBB28251.1 - 6.8e-13 49.3 0.6 1.5e-12 48.1 0.6 1.6 1 0 0 1 1 1 1 Lectin C-type domain Kinesin PF00225.23 VBB28252.1 - 1.6e-83 280.4 1.1 2.2e-83 279.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 VBB28252.1 - 2.8e-35 120.6 0.0 6.9e-35 119.3 0.0 1.7 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 VBB28252.1 - 9.9e-16 58.0 0.0 4.6e-14 52.6 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding TAT_signal PF10518.9 VBB28252.1 - 0.04 13.8 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence APG6_N PF17675.1 VBB28252.1 - 0.1 13.2 20.5 0.25 11.9 20.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Ndc1_Nup PF09531.10 VBB28252.1 - 1 8.0 4.2 1.5 7.4 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM75 PF14650.6 VBB28253.1 - 0.39 10.2 6.0 0.49 9.9 6.0 1.1 1 0 0 1 1 1 0 FAM75 family ABC_membrane PF00664.23 VBB28254.1 - 6.8e-08 32.5 5.1 2.3e-05 24.2 0.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region LktC PF06261.11 VBB28254.1 - 0.055 13.4 1.6 0.31 10.9 0.2 2.2 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Med23 PF11573.8 VBB28255.1 - 4.6e-193 644.1 34.2 3.1e-130 436.0 27.0 2.8 2 1 0 2 2 2 2 Mediator complex subunit 23 TrmE_N PF10396.9 VBB28255.1 - 3.5e-31 107.9 0.0 9.1e-31 106.6 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 VBB28255.1 - 4.8e-27 95.5 0.0 2.4e-26 93.2 0.0 2.2 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 VBB28255.1 - 5.4e-22 78.0 0.2 2.2e-21 76.1 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB28255.1 - 6.1e-11 42.1 2.2 7.5e-11 41.8 0.1 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B SH2 PF00017.24 VBB28255.1 - 1.6e-10 40.9 0.0 4.3e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 VBB28255.1 - 1.2e-07 32.0 2.5 1.2e-07 32.0 2.5 2.4 2 0 0 2 2 2 1 SOCS box RsgA_GTPase PF03193.16 VBB28255.1 - 6.5e-06 26.2 0.4 0.00042 20.3 0.1 3.4 3 1 0 3 3 3 1 RsgA GTPase Ras PF00071.22 VBB28255.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB28255.1 - 0.0014 18.8 0.1 0.0077 16.4 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 VBB28255.1 - 0.0026 17.8 0.2 0.26 11.3 0.0 2.9 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 VBB28255.1 - 0.02 14.4 1.1 1.3 8.5 0.7 3.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 VBB28255.1 - 0.047 13.1 0.5 0.46 9.9 0.1 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 VBB28255.1 - 0.057 12.9 0.2 0.22 11.0 0.1 2.0 2 1 0 2 2 2 0 ADP-ribosylation factor family AIG1 PF04548.16 VBB28255.1 - 0.074 12.4 0.2 0.15 11.3 0.2 1.5 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 VBB28255.1 - 0.12 12.1 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ERM PF00769.19 VBB28256.1 - 0.0058 16.5 18.1 0.0058 16.5 18.1 6.4 4 2 0 6 6 6 2 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 VBB28256.1 - 0.0091 16.2 19.6 0.0091 16.2 19.6 10.2 6 2 6 12 12 12 3 TATA element modulatory factor 1 TATA binding PAS_11 PF14598.6 VBB28257.1 - 5.7e-29 100.5 1.6 7.5e-25 87.3 0.2 2.7 3 0 0 3 3 3 2 PAS domain HLH PF00010.26 VBB28257.1 - 3.3e-14 52.6 1.5 5.9e-14 51.8 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 VBB28257.1 - 2.3e-10 40.5 0.1 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 VBB28257.1 - 2.5e-08 34.1 0.2 0.014 15.7 0.1 2.9 2 1 1 3 3 3 2 PAS fold PAS_9 PF13426.7 VBB28257.1 - 3.3e-05 24.1 0.0 0.019 15.2 0.0 2.5 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.10 VBB28257.1 - 0.011 16.0 0.1 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 PAS fold L51_S25_CI-B8 PF05047.16 VBB28258.1 - 2.8e-09 36.7 0.0 6.1e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Rtf2 PF04641.12 VBB28259.1 - 3.2e-77 259.4 13.7 3.7e-77 259.2 13.7 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Proton_antipo_M PF00361.20 VBB28260.1 - 1.5e-10 40.7 1.0 3.1e-10 39.7 1.0 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter LIAS_N PF16881.5 VBB28262.1 - 8.2e-23 80.9 0.1 1.5e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 VBB28262.1 - 2.6e-12 47.4 0.0 6.2e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Spore_GerAC PF05504.11 VBB28262.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Rgp1 PF08737.10 VBB28263.1 - 1.4e-23 83.8 15.0 2.2e-13 50.2 0.1 3.7 2 2 1 3 3 3 2 Rgp1 WD40 PF00400.32 VBB28264.1 - 0.00077 20.2 6.7 0.11 13.4 0.3 4.7 4 2 1 5 5 5 2 WD domain, G-beta repeat CDK2AP PF09806.9 VBB28265.1 - 8.1e-18 65.3 0.1 1e-17 65.0 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein UTP25 PF06862.12 VBB28266.1 - 1e-122 410.3 4.8 1.5e-122 409.8 4.8 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ubiquitin PF00240.23 VBB28267.1 - 7.6e-05 22.4 0.6 0.0028 17.4 0.2 2.1 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_4 PF18036.1 VBB28267.1 - 0.061 13.4 0.2 0.1 12.7 0.3 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain SUI1 PF01253.22 VBB28268.1 - 2.2e-18 66.5 0.1 3.8e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Glyco_transf_7C PF02709.14 VBB28269.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Peptidase_S28 PF05577.12 VBB28270.1 - 3.6e-62 210.6 0.0 4.2e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 MH1 PF03165.16 VBB28270.1 - 0.096 12.9 0.1 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 MH1 domain Ras PF00071.22 VBB28271.1 - 1.4e-20 73.5 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 VBB28271.1 - 4.6e-07 29.5 0.1 9.2e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB28271.1 - 1.9e-06 28.1 0.0 5.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 VBB28271.1 - 0.00014 21.9 2.3 0.00053 20.0 0.0 2.6 2 1 1 3 3 3 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 VBB28271.1 - 0.08 12.9 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 NTPase GPP34 PF05719.11 VBB28273.1 - 1.7e-52 178.5 0.0 2e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) S10_plectin PF03501.15 VBB28274.1 - 1.3e-45 153.4 0.4 2.4e-45 152.5 0.4 1.4 1 0 0 1 1 1 1 Plectin/S10 domain DUF4078 PF13300.6 VBB28274.1 - 7.7e-15 55.0 10.0 7.7e-15 55.0 10.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) TMPIT PF07851.13 VBB28274.1 - 3.9 6.6 7.8 0.26 10.5 0.7 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 VBB28274.1 - 8.4 5.7 9.5 13 5.0 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTF2 PF02136.20 VBB28275.1 - 8.3e-28 97.4 0.0 9.7e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 VBB28275.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 1 1 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 DUF4440 PF14534.6 VBB28275.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4518 PF15008.6 VBB28275.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) TMEM208_SND2 PF05620.11 VBB28276.1 - 2.2e-33 115.4 0.4 4.2e-31 108.0 0.1 2.0 1 1 1 2 2 2 2 SRP-independent targeting protein 2/TMEM208 DUF2207 PF09972.9 VBB28276.1 - 0.082 11.7 0.7 0.11 11.3 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) COX8 PF02285.15 VBB28276.1 - 1.9 8.4 7.7 0.15 12.0 2.4 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII XTBD PF11952.8 VBB28277.1 - 1.1e-23 82.7 0.3 4.2e-23 80.9 0.1 2.1 2 0 0 2 2 2 1 XRN-Two Binding Domain, XTBD mit_SMPDase PF14724.6 VBB28277.1 - 9.7e-13 47.0 7.7 9.8e-08 30.5 0.0 3.6 2 1 2 4 4 4 3 Mitochondrial-associated sphingomyelin phosphodiesterase DAO PF01266.24 VBB28278.1 - 2.6e-55 188.4 0.3 3.9e-55 187.9 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.21 VBB28278.1 - 3.6e-50 170.7 0.0 5.1e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 VBB28278.1 - 1.4e-08 34.6 0.0 2.3e-07 30.6 0.0 2.7 3 0 0 3 3 3 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 VBB28278.1 - 1.3e-06 28.6 0.4 3.5e-06 27.2 0.4 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain NAD_binding_8 PF13450.6 VBB28278.1 - 5.9e-05 23.2 0.2 0.00014 22.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 VBB28278.1 - 0.00051 19.4 0.3 0.15 11.3 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 VBB28278.1 - 0.0049 16.1 0.2 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 VBB28278.1 - 0.028 14.1 0.0 0.27 10.9 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 VBB28278.1 - 0.041 13.1 1.0 0.088 12.0 1.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 VBB28278.1 - 0.096 11.7 0.2 0.18 10.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 VBB28278.1 - 0.19 10.7 0.1 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Nic96 PF04097.14 VBB28279.1 - 6.3e-108 361.9 0.0 8e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_14 PF13428.6 VBB28279.1 - 0.00016 22.2 6.9 7.6 7.6 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat GlcNAc_2-epim PF07221.11 VBB28279.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) ANAPC3 PF12895.7 VBB28279.1 - 0.49 10.7 3.1 1.1 9.6 0.0 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Nup84_Nup100 PF04121.13 VBB28279.1 - 0.91 7.5 5.7 0.22 9.6 1.8 1.8 2 1 0 2 2 2 0 Nuclear pore protein 84 / 107 Collagen PF01391.18 VBB28280.1 - 1.8e-25 88.4 85.9 3.4e-10 39.5 34.4 3.8 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28280.1 - 7e-17 61.2 0.6 9.9e-17 60.7 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Methyltr_RsmB-F PF01189.17 VBB28281.1 - 2.9e-70 236.0 0.0 6.2e-70 234.9 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sec61_beta PF03911.16 VBB28281.1 - 5.7e-19 67.9 0.1 9.5e-19 67.2 0.1 1.4 1 0 0 1 1 1 1 Sec61beta family Methyltr_RsmF_N PF17125.5 VBB28281.1 - 4.4e-06 27.1 0.2 1.9e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 VBB28281.1 - 0.00045 20.4 0.8 0.0019 18.4 0.2 2.3 2 1 0 2 2 2 1 FtsJ-like methyltransferase Hist_deacetyl PF00850.19 VBB28282.1 - 1.3e-72 244.9 0.0 1.9e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 VBB28283.1 - 9.6e-19 67.5 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TIM PF00121.18 VBB28283.1 - 0.0062 15.9 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Y_phosphatase PF00102.27 VBB28283.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB28283.1 - 0.055 13.4 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 VBB28283.1 - 0.091 12.3 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Claudin_3 PF06653.11 VBB28284.1 - 2.2e-05 24.5 8.3 3.4e-05 23.9 8.3 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 VBB28284.1 - 5.2e-05 23.2 5.9 6.5e-05 22.9 5.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 VBB28284.1 - 0.00054 19.5 5.5 0.00076 19.0 5.5 1.1 1 0 0 1 1 1 1 Clc-like DUF4064 PF13273.6 VBB28284.1 - 0.0089 16.3 1.9 0.0089 16.3 1.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) WD40 PF00400.32 VBB28285.1 - 5.8e-19 68.1 6.9 1.2e-05 25.9 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 VBB28285.1 - 0.033 12.8 0.2 3.2 6.3 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB28285.1 - 0.038 13.3 0.4 2.2 7.5 0.1 2.7 3 0 0 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 VBB28285.1 - 0.12 11.0 0.0 12 4.6 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like Tocopherol_cycl PF14249.6 VBB28285.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Tocopherol cyclase Neur_chan_LBD PF02931.23 VBB28286.1 - 1.1e-45 155.8 7.3 1.6e-45 155.2 7.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB28286.1 - 1.9e-19 70.7 2.7 3e-19 70.0 2.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region FLYWCH PF04500.16 VBB28288.1 - 5.5e-10 39.2 0.2 1.1e-09 38.3 0.2 1.5 1 0 0 1 1 1 1 FLYWCH zinc finger domain GRP PF07172.11 VBB28291.1 - 0.12 13.1 21.9 0.14 12.9 21.9 1.2 1 0 0 1 1 1 0 Glycine rich protein family Ank_2 PF12796.7 VBB28292.1 - 9.5e-14 51.8 0.1 2.2e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB28292.1 - 2.8e-12 46.6 0.5 0.0064 16.8 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 VBB28292.1 - 8.5e-09 35.8 0.6 0.011 16.2 0.1 3.7 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB28292.1 - 3.3e-08 33.2 0.3 0.096 13.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 VBB28292.1 - 1.8e-05 25.0 1.9 0.063 13.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat LTP_2 PF14368.6 VBB28292.1 - 0.062 13.4 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 Probable lipid transfer RRM_1 PF00076.22 VBB28293.1 - 3.3e-19 68.5 0.0 1.7e-06 27.8 0.0 4.2 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB28293.1 - 0.0055 16.7 0.0 1.4 9.0 0.0 3.6 4 0 0 4 4 4 1 RNA binding motif Toprim_2 PF13155.6 VBB28293.1 - 0.032 14.6 0.1 0.63 10.5 0.0 2.4 1 1 0 2 2 2 0 Toprim-like PHM7_cyt PF14703.6 VBB28293.1 - 0.034 14.4 0.0 14 5.9 0.0 3.9 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter RRM_8 PF11835.8 VBB28293.1 - 0.078 13.2 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 RRM-like domain PAN_1 PF00024.26 VBB28294.1 - 9.7e-45 150.4 43.9 3.6e-10 39.6 0.5 7.3 7 0 0 7 7 7 6 PAN domain PAN_4 PF14295.6 VBB28294.1 - 0.00036 20.4 22.3 0.051 13.5 0.1 6.2 6 0 0 6 6 6 3 PAN domain tRNA-synt_1d PF00750.19 VBB28294.1 - 0.099 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF743 PF05332.11 VBB28294.1 - 0.15 12.1 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF743) BOP1NT PF08145.12 VBB28295.1 - 1.3e-97 326.8 5.9 2.1e-97 326.1 5.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 VBB28295.1 - 1.1e-14 54.5 0.0 4.7e-06 27.2 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28295.1 - 1.4e-06 28.5 0.0 0.03 14.6 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ThiF PF00899.21 VBB28296.1 - 5.6e-47 160.2 1.1 9.8e-47 159.4 0.8 1.4 1 1 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 VBB28296.1 - 0.00035 20.0 0.1 0.00087 18.7 0.1 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 VBB28296.1 - 0.0032 17.9 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding PglD_N PF17836.1 VBB28296.1 - 0.0073 16.9 0.1 0.019 15.6 0.1 1.8 1 0 0 1 1 1 1 PglD N-terminal domain Shikimate_DH PF01488.20 VBB28296.1 - 0.032 14.3 0.2 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 VBB28296.1 - 0.044 13.4 0.1 0.085 12.4 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 VBB28296.1 - 0.061 13.0 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 VBB28296.1 - 0.073 13.3 0.3 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 VBB28296.1 - 0.1 11.8 0.4 0.17 11.1 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 VBB28296.1 - 0.46 10.7 8.6 0.09 13.0 1.8 2.9 3 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain zf-RING_2 PF13639.6 VBB28297.1 - 3.7e-13 49.6 6.0 3.7e-13 49.6 6.0 4.0 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB28297.1 - 1.1e-08 34.8 4.6 1.1e-08 34.8 4.6 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 VBB28297.1 - 1.6e-08 34.2 3.0 1.6e-08 34.2 3.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 VBB28297.1 - 2.2e-08 34.3 5.4 2.2e-08 34.3 5.4 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB28297.1 - 1.3e-05 24.9 4.5 1.3e-05 24.9 4.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB28297.1 - 1.5e-05 24.8 3.5 1.5e-05 24.8 3.5 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 VBB28297.1 - 0.011 15.8 2.8 0.011 15.8 2.8 3.0 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger I-set PF07679.16 VBB28298.1 - 3.2e-73 241.9 0.0 2.3e-22 78.9 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB28298.1 - 1.6e-63 211.3 0.0 4.6e-15 56.0 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 VBB28298.1 - 2e-42 143.2 0.0 2.5e-12 46.8 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 VBB28298.1 - 2.6e-41 139.8 0.0 3e-11 43.5 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 VBB28298.1 - 2e-31 108.4 0.1 1.1e-05 25.5 0.0 7.4 4 4 2 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB28298.1 - 1.4e-13 50.7 0.0 0.055 13.5 0.0 4.3 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB28298.1 - 2.9e-12 45.9 0.0 0.018 14.6 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Izumo-Ig PF16706.5 VBB28298.1 - 3.4e-06 27.0 0.0 2.5 8.2 0.0 4.6 4 1 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB28298.1 - 9.9e-06 25.5 0.0 6.9 6.8 0.0 4.6 4 1 0 4 4 4 2 C17orf99 Ig domain zf-RRN7 PF11781.8 VBB28298.1 - 0.00068 19.3 2.0 26 4.6 0.0 4.5 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 C1-set PF07654.15 VBB28298.1 - 0.0073 16.7 0.0 0.23 11.9 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 VBB28298.1 - 0.011 15.7 0.0 18 5.3 0.0 3.7 4 1 0 4 4 4 0 CD47 immunoglobulin-like domain BiPBP_C PF06832.12 VBB28298.1 - 0.11 12.5 0.0 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family XRN1_DBM PF18245.1 VBB28298.1 - 0.2 11.7 1.9 0.58 10.2 0.6 2.3 2 0 0 2 2 2 0 5-3 exonuclease XRN1 DCP1-binding motif fn3 PF00041.21 VBB28299.1 - 3.3e-34 117.1 5.4 2.1e-12 47.2 0.1 4.1 4 0 0 4 4 4 3 Fibronectin type III domain I-set PF07679.16 VBB28299.1 - 7.9e-17 61.1 0.0 2.2e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB28299.1 - 6.4e-16 58.7 0.0 5.3e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 VBB28299.1 - 8.8e-15 54.7 0.3 2.7e-14 53.1 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 VBB28299.1 - 3.6e-08 33.6 0.0 9.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB28299.1 - 8.7e-08 32.3 0.1 3.4e-06 27.2 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 VBB28299.1 - 0.001 17.9 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.12 VBB28299.1 - 0.011 15.8 0.1 0.029 14.4 0.1 1.8 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB28299.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_4 PF16680.5 VBB28299.1 - 0.18 12.1 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain DUF4719 PF15843.5 VBB28300.1 - 0.33 11.0 2.9 0.6 10.2 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) 7tm_1 PF00001.21 VBB28302.1 - 3.2e-56 190.6 7.1 4.1e-56 190.2 7.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB28302.1 - 6.1e-05 22.8 6.1 6.1e-05 22.8 6.1 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1461 PF07314.11 VBB28302.1 - 0.071 13.0 0.2 0.071 13.0 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) 7tm_4 PF13853.6 VBB28302.1 - 0.12 12.1 8.6 0.14 11.9 2.2 2.2 2 0 0 2 2 2 0 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 VBB28302.1 - 0.14 11.5 16.2 0.63 9.4 2.1 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx GRIP PF01465.20 VBB28303.1 - 1.3e-09 37.8 0.2 2.5e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 GRIP domain KASH_CCD PF14662.6 VBB28303.1 - 0.007 16.2 11.0 0.12 12.1 3.9 3.0 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 VBB28303.1 - 0.0093 16.2 3.3 0.0093 16.2 3.3 2.6 1 1 0 2 2 2 1 Autophagy protein 16 (ATG16) KLRAQ PF10205.9 VBB28303.1 - 0.47 10.7 6.5 3.2 8.1 0.2 3.5 2 1 2 4 4 4 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 VBB28303.1 - 0.49 10.4 5.9 16 5.6 1.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PAN_1 PF00024.26 VBB28304.1 - 0.0012 18.7 0.7 0.0027 17.6 0.7 1.6 1 0 0 1 1 1 1 PAN domain Tho2 PF11262.8 VBB28305.1 - 6.2e-81 271.9 2.2 6.2e-81 271.9 2.2 2.1 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 VBB28305.1 - 1e-65 222.6 10.4 4.6e-42 144.5 1.9 3.6 2 1 1 3 3 3 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 VBB28305.1 - 5.2e-29 100.1 0.1 3e-28 97.7 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit PI-PLC-X PF00388.19 VBB28306.1 - 2.6e-08 33.6 0.0 4.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Mito_carr PF00153.27 VBB28307.1 - 2.6e-41 139.5 4.8 3.1e-18 65.5 0.4 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 VBB28307.1 - 0.00015 21.0 0.5 0.35 10.0 0.0 2.6 1 1 1 3 3 3 2 Gammaproteobacterial serine protease Glycos_transf_2 PF00535.26 VBB28308.1 - 1.4e-33 116.1 0.0 2.4e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB28308.1 - 1.4e-24 86.8 3.1 2.6e-20 73.0 2.0 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 VBB28308.1 - 0.00055 19.5 0.2 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase CDtoxinA PF03498.14 VBB28308.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Glyco_tranf_2_2 PF10111.9 VBB28308.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 VBB28308.1 - 0.13 13.0 0.5 3.5 8.4 0.1 2.5 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Dynamitin PF04912.14 VBB28309.1 - 1.1e-58 199.4 17.0 3.7e-31 108.8 9.3 2.0 1 1 1 2 2 2 2 Dynamitin DUF1572 PF07609.11 VBB28309.1 - 0.01 15.7 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) DASH_Dam1 PF08653.10 VBB28309.1 - 0.16 11.8 4.0 10 6.0 0.1 4.3 5 1 0 5 5 5 0 DASH complex subunit Dam1 DUF2935 PF11155.8 VBB28309.1 - 0.38 11.1 5.0 11 6.4 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) MerR-DNA-bind PF09278.11 VBB28309.1 - 0.51 10.9 9.5 9.5 6.8 0.0 4.8 5 0 0 5 5 5 0 MerR, DNA binding Hemerythrin PF01814.23 VBB28309.1 - 0.91 10.1 7.5 18 5.9 0.1 3.6 3 2 0 3 3 3 0 Hemerythrin HHE cation binding domain CR6_interact PF10147.9 VBB28309.1 - 1.4 8.6 10.1 5 6.8 2.0 2.7 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Phage_GPO PF05929.11 VBB28309.1 - 1.5 8.3 7.2 1.1 8.8 2.7 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YvrJ PF12841.7 VBB28309.1 - 2 8.0 7.1 33 4.1 0.0 4.2 5 0 0 5 5 5 0 YvrJ protein family V-SNARE PF05008.15 VBB28309.1 - 4.3 7.8 9.2 0.27 11.6 1.3 3.1 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-BED PF02892.15 VBB28310.1 - 1.5e-05 24.9 14.2 0.00016 21.6 5.5 2.5 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_12 PF18658.1 VBB28310.1 - 0.0018 17.8 8.6 0.018 14.6 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger C2H2-type OrsD PF12013.8 VBB28310.1 - 0.013 15.9 6.2 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D FYVE PF01363.21 VBB28310.1 - 0.021 14.9 8.4 0.026 14.7 4.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf-BED PF02892.15 VBB28311.1 - 3.1e-05 23.9 21.9 0.0096 15.9 7.4 2.5 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_12 PF18658.1 VBB28311.1 - 0.086 12.4 9.5 0.23 11.1 3.1 2.5 2 0 0 2 2 2 0 Zinc-finger C2H2-type DUF3222 PF11519.8 VBB28311.1 - 0.11 12.7 4.9 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) FYVE PF01363.21 VBB28311.1 - 3.4 7.9 10.9 0.27 11.4 1.9 2.4 2 0 0 2 2 2 0 FYVE zinc finger Y_phosphatase PF00102.27 VBB28312.1 - 5.2e-74 248.8 0.5 7.4e-74 248.3 0.5 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Homeodomain PF00046.29 VBB28312.1 - 1.3e-19 69.8 0.6 3.4e-19 68.4 0.6 1.8 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 VBB28312.1 - 1.5e-05 25.1 6.2 3.5e-05 24.0 6.2 1.6 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 VBB28312.1 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Y_phosphatase3 PF13350.6 VBB28312.1 - 0.016 15.2 0.1 0.035 14.1 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 VBB28312.1 - 0.021 14.6 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain UNC45-central PF11701.8 VBB28312.1 - 0.026 14.5 0.0 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central PTPlike_phytase PF14566.6 VBB28312.1 - 0.038 14.1 0.3 0.097 12.8 0.3 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate TAF PF02969.17 VBB28313.1 - 0.0076 16.4 0.4 0.018 15.2 0.4 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CVNH PF08881.10 VBB28313.1 - 0.028 15.1 0.2 1.8 9.3 0.0 2.2 2 0 0 2 2 2 0 CVNH domain Ribosomal_L7Ae PF01248.26 VBB28314.1 - 6.4e-23 80.3 0.6 1.2e-22 79.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.6 VBB28314.1 - 0.029 14.5 0.4 0.029 14.5 0.4 1.8 2 0 0 2 2 2 0 Heavy-metal resistance MFS_1 PF07690.16 VBB28315.1 - 2.2e-12 46.6 47.5 7.6e-10 38.2 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Importin_rep_3 PF18806.1 VBB28316.1 - 4.5e-05 23.4 0.6 0.0002 21.3 0.1 2.4 3 0 0 3 3 3 1 Importin 13 repeat NTF2 PF02136.20 VBB28316.1 - 0.017 15.7 0.2 0.47 11.0 0.0 3.0 2 1 1 3 3 3 0 Nuclear transport factor 2 (NTF2) domain NitrOD2 PF18550.1 VBB28316.1 - 0.094 12.9 0.7 1.1 9.4 0.0 3.0 3 1 0 3 3 3 0 Nitrososphaera output domain 2 ubiquitin PF00240.23 VBB28317.1 - 3.3e-170 552.2 24.0 2.5e-33 113.6 0.4 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 VBB28317.1 - 7.3e-80 262.8 26.2 2.5e-15 56.1 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 VBB28317.1 - 3e-29 101.3 11.7 0.00048 20.5 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Ubiquitin_5 PF18037.1 VBB28317.1 - 7.2e-19 68.0 10.2 0.038 14.4 0.1 5.1 1 1 3 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 VBB28317.1 - 8.3e-19 67.3 7.2 0.052 13.5 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 VBB28317.1 - 2e-17 63.3 5.4 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 VBB28317.1 - 3.3e-16 59.7 1.7 0.5 11.0 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Big_7 PF17957.1 VBB28317.1 - 1.4e-12 48.1 0.2 4.2 8.2 0.0 5.2 5 0 0 5 5 5 5 Bacterial Ig domain Sde2_N_Ubi PF13019.6 VBB28317.1 - 3.7e-11 43.1 0.5 2.9 7.7 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 VBB28317.1 - 2.4e-09 36.9 3.0 1 8.6 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase DUF2870 PF11069.8 VBB28317.1 - 1.8e-07 31.5 0.0 40 4.7 0.0 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 VBB28317.1 - 3e-07 30.4 33.8 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain UDP-g_GGTase PF06427.11 VBB28317.1 - 1.3e-06 28.4 7.2 6 7.0 0.0 5.0 5 0 0 5 5 5 4 UDP-glucose:Glycoprotein Glucosyltransferase DUF3861 PF12977.7 VBB28317.1 - 1.7e-06 28.1 5.7 22 5.3 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Big_3_3 PF13750.6 VBB28317.1 - 2.4e-06 27.3 0.0 34 4.1 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 VBB28317.1 - 2.2e-05 24.0 0.2 29 4.0 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) PDGLE PF13190.6 VBB28317.1 - 0.00016 21.5 10.8 23 4.9 0.1 5.8 1 1 2 5 5 5 0 PDGLE domain ORF11CD3 PF10549.9 VBB28317.1 - 0.00038 20.5 0.0 1.2e+02 2.9 0.0 5.6 5 0 0 5 5 5 0 ORF11CD3 domain ACT_5 PF13710.6 VBB28317.1 - 0.00082 19.2 6.1 59 3.6 0.0 5.2 5 0 0 5 5 5 0 ACT domain ACT_4 PF13291.6 VBB28317.1 - 0.0011 19.5 1.7 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain ProRS-C_2 PF09181.10 VBB28317.1 - 0.03 14.4 9.1 1e+02 3.1 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 VBB28317.1 - 0.089 11.7 0.0 1.2e+02 1.4 0.0 3.7 4 0 0 4 4 4 0 Baculovirus P48 protein FlgD_ig PF13860.6 VBB28317.1 - 0.96 9.4 12.8 1.1e+02 2.7 0.1 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain YcgR_2 PF12945.7 VBB28317.1 - 1.5 9.0 6.2 3.6e+02 1.4 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR Phage_sheath_1N PF17481.2 VBB28317.1 - 6.7 7.3 11.0 1.1e+02 3.3 0.7 4.6 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain PAP2_C PF14360.6 VBB28318.1 - 3.1e-25 88.5 11.2 3.1e-25 88.5 11.2 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 VBB28318.1 - 5.9e-14 52.3 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 VBB28318.1 - 2.4e-05 24.2 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 VBB28318.1 - 0.00058 19.9 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 VBB28318.1 - 0.00062 19.6 10.9 0.00062 19.6 10.9 1.9 1 1 0 1 1 1 1 PAP2 superfamily SAM_3 PF18016.1 VBB28318.1 - 0.075 12.8 0.5 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PAP2_3 PF14378.6 VBB28318.1 - 0.54 9.9 16.2 0.16 11.7 12.9 1.7 1 1 1 2 2 2 0 PAP2 superfamily Kinesin PF00225.23 VBB28319.1 - 5.2e-106 354.3 0.6 5.2e-106 354.3 0.6 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 VBB28319.1 - 1.3e-22 80.4 0.0 1.3e-22 80.4 0.0 2.8 3 1 1 4 4 4 1 Microtubule binding Glu-tRNAGln PF02686.15 VBB28319.1 - 7.6e-07 29.3 1.2 2.3e-06 27.8 0.2 2.4 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit ApoO PF09769.9 VBB28319.1 - 0.0034 17.3 3.0 0.86 9.6 0.9 3.0 2 1 0 2 2 2 2 Apolipoprotein O GARP PF16731.5 VBB28319.1 - 2 8.0 11.2 1.5 8.5 1.4 3.9 3 1 1 4 4 4 0 Glutamic acid/alanine-rich protein of Trypanosoma Cwf_Cwc_15 PF04889.12 VBB28320.1 - 0.013 15.2 26.4 0.019 14.7 26.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 VBB28320.1 - 0.046 14.4 18.3 0.068 13.9 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CNDH2_C PF16858.5 VBB28320.1 - 0.14 12.0 11.0 0.16 11.8 11.0 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 VBB28320.1 - 0.45 8.8 18.1 0.51 8.6 18.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 VBB28320.1 - 0.91 8.8 29.2 1.3 8.3 29.2 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 VBB28320.1 - 1.1 7.3 27.8 1.3 7.0 27.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF1168 PF06658.12 VBB28320.1 - 1.5 8.6 10.7 2 8.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pox_Ag35 PF03286.14 VBB28320.1 - 1.6 8.5 13.1 2.3 8.0 13.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 VBB28320.1 - 2.4 6.2 21.0 2.5 6.2 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family Rhabdo_ncap PF00945.18 VBB28320.1 - 4.8 6.0 12.8 5.4 5.8 12.8 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein NPR3 PF03666.13 VBB28320.1 - 5 5.8 9.8 5.5 5.7 9.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 VBB28320.1 - 5.3 6.4 19.9 6.3 6.1 19.9 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 VBB28320.1 - 9.3 4.7 15.0 8.5 4.8 15.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hexokinase_2 PF03727.16 VBB28321.1 - 1.1e-74 250.8 0.0 1.7e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 VBB28321.1 - 9.3e-72 241.1 0.0 1.4e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Collagen PF01391.18 VBB28321.1 - 1.4e-08 34.3 24.4 2.7e-08 33.4 24.4 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) MitMem_reg PF13012.6 VBB28322.1 - 2.4e-32 111.7 0.1 4.5e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 VBB28322.1 - 4.8e-32 110.4 0.8 2.7e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 VBB28322.1 - 0.18 11.5 3.1 0.3 10.8 3.1 1.4 1 1 0 1 1 1 0 Connexin Ureide_permease PF07168.11 VBB28322.1 - 4.4 6.0 4.6 6 5.5 4.0 1.4 1 1 0 1 1 1 0 Ureide permease WD40 PF00400.32 VBB28323.1 - 2.6e-17 62.8 3.3 0.00011 22.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28323.1 - 9.7e-09 35.4 0.0 0.0028 17.9 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain rRNA_processing PF08524.11 VBB28324.1 - 3.3e-12 46.7 15.1 3.3e-12 46.7 15.1 2.2 2 0 0 2 2 2 1 rRNA processing Rpr2 PF04032.16 VBB28324.1 - 2.8e-11 43.6 3.8 2.8e-11 43.6 3.8 2.8 3 1 0 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_15 PF17032.5 VBB28324.1 - 0.038 14.7 0.5 0.12 13.1 0.5 1.9 1 0 0 1 1 1 0 zinc-ribbon family ADD_DNMT3 PF17980.1 VBB28324.1 - 0.05 13.6 0.8 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Vma12 PF11712.8 VBB28324.1 - 0.97 9.5 10.5 0.51 10.4 6.1 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HALZ PF02183.18 VBB28325.1 - 3 8.1 9.2 3.4 7.9 0.8 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper PIP5K PF01504.18 VBB28326.1 - 8.5e-72 241.7 1.8 3.1e-55 187.4 0.2 2.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase C2 PF00168.30 VBB28326.1 - 1.9e-14 53.8 0.0 4.5e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain HEAT PF02985.22 VBB28328.1 - 0.15 12.4 1.6 2.2 8.8 0.3 3.4 2 0 0 2 2 2 0 HEAT repeat RINGv PF12906.7 VBB28329.1 - 5.6e-13 48.8 5.4 1.1e-12 47.8 5.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 VBB28329.1 - 0.038 14.3 5.2 0.11 12.8 5.2 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 VBB28329.1 - 1.4 8.8 4.5 4.2 7.3 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Exo70 PF03081.15 VBB28330.1 - 1.3e-49 169.2 0.4 1.3e-49 169.2 0.4 2.1 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 VBB28330.1 - 5.2e-06 26.4 4.0 5.2e-06 26.4 4.0 2.8 3 1 0 3 3 3 1 Sec34-like family COG5 PF10392.9 VBB28330.1 - 0.027 14.7 1.1 1.6 8.9 0.9 2.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HMW1C_N PF18071.1 VBB28330.1 - 0.044 13.6 0.8 0.15 11.8 0.3 2.2 1 1 1 2 2 2 0 HMW1C N-terminal Nup54 PF13874.6 VBB28330.1 - 0.14 12.2 5.5 0.35 11.0 5.5 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RasGEF PF00617.19 VBB28332.1 - 2.1e-42 145.3 0.1 5.6e-42 143.9 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 VBB28332.1 - 1.5e-12 47.6 0.0 1.3e-10 41.5 0.0 2.9 1 1 1 2 2 2 2 RasGEF N-terminal motif RhoGEF PF00621.20 VBB28332.1 - 2e-10 41.2 0.8 8.8e-10 39.1 0.3 2.5 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 VBB28332.1 - 0.0001 22.8 0.1 0.00024 21.5 0.1 1.7 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 VBB28332.1 - 0.0056 16.7 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 PH domain Ground-like PF04155.18 VBB28334.1 - 7.5e-23 81.0 3.4 1e-22 80.6 3.4 1.2 1 0 0 1 1 1 1 Ground-like domain CUB PF00431.20 VBB28335.1 - 1.1e-54 183.4 1.0 5e-14 52.6 0.1 5.0 4 1 1 5 5 5 4 CUB domain Ldl_recept_a PF00057.18 VBB28335.1 - 0.00084 19.5 4.4 0.0018 18.4 4.4 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A YcxB PF14317.6 VBB28335.1 - 2.1 8.1 4.8 5.7 6.7 0.1 3.1 3 0 0 3 3 3 0 YcxB-like protein SPRY PF00622.28 VBB28336.1 - 8.9e-26 90.4 0.3 2.1e-25 89.2 0.3 1.7 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 VBB28336.1 - 2.7e-12 46.8 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 VBB28336.1 - 0.059 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 LisH Dus PF01207.17 VBB28337.1 - 5.6e-52 176.8 0.1 7.7e-52 176.3 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 VBB28337.1 - 2.5e-06 28.1 0.0 5.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Zf_RING PF16744.5 VBB28337.1 - 0.00011 22.2 1.7 0.011 15.8 0.5 2.6 2 0 0 2 2 2 2 KIAA1045 RING finger DHO_dh PF01180.21 VBB28337.1 - 0.11 11.7 0.4 0.31 10.2 0.4 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase PEP_mutase PF13714.6 VBB28337.1 - 0.14 11.6 0.0 2.5 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase Peptidase_M1 PF01433.20 VBB28338.1 - 1.7e-49 168.4 0.9 2.6e-49 167.7 0.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 VBB28338.1 - 1.9e-27 95.6 0.0 4e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Methyltransf_16 PF10294.9 VBB28338.1 - 1.2e-19 70.8 0.1 2.3e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Peptidase_M1_N PF17900.1 VBB28338.1 - 4.1e-19 69.5 0.0 6.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Methyltransf_12 PF08242.12 VBB28338.1 - 3.8e-05 24.4 0.0 0.00023 21.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB28338.1 - 0.00024 21.7 0.0 0.0015 19.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB28338.1 - 0.0017 18.9 0.0 0.0077 16.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB28338.1 - 0.0035 17.2 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NatB_MDM20 PF09797.9 VBB28338.1 - 0.028 13.4 0.2 0.047 12.6 0.2 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit RNA_lig_T4_1 PF09511.10 VBB28338.1 - 0.042 13.7 0.5 0.13 12.1 0.5 1.9 1 1 0 1 1 1 0 RNA ligase TehB PF03848.14 VBB28338.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 VBB28338.1 - 0.066 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) bZIP_2 PF07716.15 VBB28339.1 - 4.1e-12 46.0 12.6 6e-12 45.5 12.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 VBB28339.1 - 0.00024 21.1 9.4 0.00038 20.5 9.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 VBB28339.1 - 0.0074 16.6 3.4 0.021 15.1 0.9 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family Nup54 PF13874.6 VBB28339.1 - 0.029 14.5 3.4 0.036 14.2 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Cnn_1N PF07989.11 VBB28339.1 - 0.032 14.4 4.9 0.055 13.6 4.9 1.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Tho2 PF11262.8 VBB28339.1 - 0.33 10.1 3.5 0.37 9.9 3.5 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 VBB28339.1 - 0.97 9.2 6.8 1.5 8.7 2.4 2.2 1 1 1 2 2 2 0 Septum formation initiator SIR2 PF02146.17 VBB28341.1 - 2.7e-50 170.8 0.0 4.5e-50 170.0 0.0 1.4 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 VBB28341.1 - 0.16 11.7 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Myosin_head PF00063.21 VBB28342.1 - 2.2e-294 978.0 2.8 2.2e-294 978.0 2.8 2.9 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 VBB28342.1 - 1.4e-152 509.9 268.8 1.8e-152 509.5 268.8 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 VBB28342.1 - 1.5e-15 56.7 0.5 3.6e-15 55.5 0.5 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 VBB28342.1 - 3.6e-05 23.5 43.6 3.6e-05 23.5 43.6 8.0 1 1 5 6 6 6 2 Intermediate filament protein THP2 PF09432.10 VBB28342.1 - 3.7e-05 23.8 9.1 3.7e-05 23.8 9.1 10.3 4 3 7 12 12 12 1 Tho complex subunit THP2 Tugs PF17840.1 VBB28342.1 - 0.064 13.5 1.3 0.76 10.0 1.3 3.0 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain AAA_19 PF13245.6 VBB28342.1 - 0.5 10.7 4.0 1.6 9.0 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 VBB28342.1 - 0.71 10.1 0.0 0.71 10.1 0.0 6.2 4 2 3 7 7 7 0 AAA domain MscS_porin PF12795.7 VBB28342.1 - 0.92 9.0 243.4 0.036 13.6 7.7 11.2 1 1 7 10 10 10 0 Mechanosensitive ion channel porin domain TUDOR PF00567.24 VBB28343.1 - 3.2e-12 46.5 0.1 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Tudor domain DUF4291 PF14124.6 VBB28343.1 - 0.15 11.9 0.1 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4291) Collagen PF01391.18 VBB28343.1 - 0.4 10.5 1.2 8.4 6.2 0.1 2.3 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) Nuc_sug_transp PF04142.15 VBB28344.1 - 2.1e-123 411.5 23.5 2.5e-123 411.3 23.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 VBB28344.1 - 3.4e-05 24.0 36.8 0.00022 21.4 13.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 VBB28344.1 - 0.0012 18.1 21.1 0.0029 16.9 21.1 1.6 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 VBB28344.1 - 0.0024 17.2 9.9 0.0024 17.2 9.9 2.0 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport Chordopox_A13L PF05961.11 VBB28344.1 - 0.038 14.2 0.1 0.38 11.0 0.0 2.7 2 0 0 2 2 2 0 Chordopoxvirus A13L protein EmrE PF13536.6 VBB28344.1 - 1.9 8.0 18.9 22 4.5 18.9 2.3 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter PNK3P PF08645.11 VBB28345.1 - 5.1e-48 162.8 0.0 3e-47 160.3 0.0 2.0 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 VBB28345.1 - 5.3e-17 62.3 0.4 2.8e-14 53.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 VBB28345.1 - 1.8e-07 30.7 0.2 0.0027 17.0 0.1 2.2 1 1 1 2 2 2 2 Zeta toxin AAA_18 PF13238.6 VBB28345.1 - 0.002 18.7 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB28345.1 - 0.0032 17.9 0.0 0.0056 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 VBB28345.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 VBB28345.1 - 0.021 15.2 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 VBB28345.1 - 0.021 15.3 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 VBB28345.1 - 0.039 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_22 PF13401.6 VBB28345.1 - 0.04 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 VBB28345.1 - 0.067 13.1 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 VBB28345.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 VBB28345.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 VBB28345.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 VBB28345.1 - 0.11 12.6 0.0 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.10 VBB28345.1 - 0.12 11.8 0.6 2.2 7.6 0.0 2.1 1 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 VBB28345.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 VBB28345.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Hydrolase_6 PF13344.6 VBB28345.1 - 0.16 12.1 0.0 0.91 9.7 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mg_chelatase PF01078.21 VBB28345.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MANEC PF07502.14 VBB28345.1 - 0.21 11.9 4.9 0.084 13.2 1.1 2.3 2 1 0 2 2 2 0 MANEC domain Zona_pellucida PF00100.23 VBB28346.1 - 2.3e-09 37.4 9.4 3.6e-09 36.8 9.4 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain DUF262 PF03235.14 VBB28347.1 - 0.039 14.1 0.3 0.044 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Integrin_alpha2 PF08441.12 VBB28348.1 - 1.8e-49 168.9 0.0 2.2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 VBB28348.1 - 2.2e-28 98.0 35.6 7.6e-09 35.5 5.5 4.9 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.6 VBB28348.1 - 3e-17 63.0 32.9 6e-07 30.0 6.1 3.6 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 VBB28348.1 - 1.4e-05 25.2 19.2 0.0003 21.0 1.1 5.6 6 0 0 6 6 6 3 FG-GAP repeat HisK_sensor PF18698.1 VBB28348.1 - 0.022 15.1 0.2 0.87 10.0 0.0 2.9 2 0 0 2 2 2 0 Histidine kinase sensor domain TcdB_toxin_midN PF12256.8 VBB28348.1 - 0.7 9.2 4.7 2.7 7.3 0.1 3.5 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region WH1 PF00568.23 VBB28349.1 - 1.5e-05 24.9 0.1 2.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 WH1 domain Retinal PF15449.6 VBB28349.1 - 5.3 4.7 11.6 6.6 4.4 11.6 1.0 1 0 0 1 1 1 0 Retinal protein TPR_19 PF14559.6 VBB28350.1 - 1.3e-35 121.7 56.7 4.2e-05 24.0 1.5 18.3 13 5 8 21 21 21 10 Tetratricopeptide repeat TPR_14 PF13428.6 VBB28350.1 - 6.7e-30 101.2 37.9 0.051 14.4 0.2 18.7 11 5 9 20 20 20 7 Tetratricopeptide repeat TPR_2 PF07719.17 VBB28350.1 - 4.1e-24 82.7 65.5 0.0015 18.5 0.0 19.7 22 0 0 22 22 21 9 Tetratricopeptide repeat TPR_16 PF13432.6 VBB28350.1 - 3.9e-19 69.0 25.9 0.028 15.0 0.1 11.2 8 2 4 12 12 12 7 Tetratricopeptide repeat TPR_21 PF09976.9 VBB28350.1 - 6.1e-17 62.0 27.6 4.4e-05 23.3 0.3 7.9 5 2 3 9 9 9 5 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 VBB28350.1 - 2e-15 56.7 43.5 0.0037 17.4 0.2 10.4 7 1 4 11 11 11 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 VBB28350.1 - 3.2e-14 51.9 45.1 0.016 15.4 0.0 16.1 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_7 PF13176.6 VBB28350.1 - 1.3e-10 40.5 29.2 0.033 14.2 0.0 12.2 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB28350.1 - 3.2e-10 39.4 51.7 0.0023 17.7 0.0 15.6 16 0 0 16 16 16 1 Tetratricopeptide repeat TPR_6 PF13174.6 VBB28350.1 - 2e-09 37.4 37.6 4.9 8.0 0.0 16.1 17 1 1 18 18 16 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB28350.1 - 1.7e-05 25.0 48.2 0.027 14.7 1.2 14.4 11 3 3 14 14 13 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB28350.1 - 0.0056 16.3 0.1 0.0056 16.3 0.1 9.9 9 1 1 10 10 10 2 TPR repeat HemY_N PF07219.13 VBB28350.1 - 0.016 15.4 3.2 3.7 7.8 0.1 5.2 4 1 1 5 5 5 0 HemY protein N-terminus PknG_TPR PF16918.5 VBB28350.1 - 0.071 11.8 4.2 1 8.0 0.0 3.7 5 0 0 5 5 5 0 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 VBB28350.1 - 0.085 13.2 21.7 16 5.9 0.2 8.5 8 1 0 8 8 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 VBB28350.1 - 0.33 11.0 12.3 0.48 10.4 0.0 5.1 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 VBB28350.1 - 0.65 10.2 17.0 2.1 8.6 0.1 6.9 6 1 2 8 8 7 0 Tetratricopeptide repeat SIL1 PF16782.5 VBB28350.1 - 1.1 8.4 8.6 0.026 13.7 0.5 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 SMBP PF16785.5 VBB28350.1 - 2.8 8.2 5.3 45 4.3 0.9 4.0 3 0 0 3 3 3 0 Small metal-binding protein Mating_N PF12731.7 VBB28351.1 - 0.16 12.1 1.0 0.61 10.2 0.2 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 Pkinase PF00069.25 VBB28353.1 - 4.6e-75 252.4 0.0 5.9e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28353.1 - 3.5e-41 141.2 0.0 4.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB28353.1 - 2.8e-05 24.2 0.2 0.0019 18.2 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB28353.1 - 0.0009 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB28353.1 - 0.0044 16.0 0.2 0.0072 15.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 VBB28353.1 - 0.0078 15.8 0.3 0.02 14.5 0.3 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 VBB28353.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_Me_trans PF04252.13 VBB28353.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Choline_kinase PF01633.20 VBB28354.1 - 3.4e-52 177.1 7.2 5.1e-52 176.5 3.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 VBB28354.1 - 5.7e-07 29.7 0.0 8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 VBB28354.1 - 9.7e-05 21.8 1.8 0.00015 21.2 1.8 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase VHS PF00790.19 VBB28357.1 - 1.6e-28 99.4 0.1 2.6e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 VBB28357.1 - 2.4e-18 65.5 0.1 6.2e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB28357.1 - 4.2e-12 45.7 0.0 9.2e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB28357.1 - 1.7e-11 43.6 0.0 5.4e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain CutA1 PF03091.15 VBB28358.1 - 7.2e-38 128.4 0.9 9.9e-38 128.0 0.9 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein COPIIcoated_ERV PF07970.12 VBB28360.1 - 6.4e-77 258.3 0.3 8.3e-77 258.0 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 VBB28360.1 - 6.5e-24 84.1 1.7 2.5e-23 82.3 0.1 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HTH_37 PF13744.6 VBB28362.1 - 0.017 15.1 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Spem1 PF15670.5 VBB28362.1 - 6.7 6.2 12.2 0.95 9.0 8.1 1.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 EF-hand_1 PF00036.32 VBB28363.1 - 6.7e-19 66.0 2.9 1.6e-07 30.3 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 VBB28363.1 - 1.8e-18 66.8 0.4 1.8e-17 63.5 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB28363.1 - 1.8e-14 52.3 1.4 1.9e-05 24.2 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 VBB28363.1 - 4.8e-12 44.8 1.1 4.1e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 VBB28363.1 - 3.7e-10 39.5 0.5 9.3e-05 22.2 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB28363.1 - 7.1e-05 23.1 0.2 0.0034 17.7 0.2 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 VBB28363.1 - 0.00013 21.8 1.0 0.6 10.1 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 VBB28363.1 - 0.069 13.1 0.7 2.9 7.8 0.1 2.1 1 1 0 2 2 2 0 Caleosin related protein S10_plectin PF03501.15 VBB28363.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain tRNA-synt_1g PF09334.11 VBB28364.1 - 6e-72 242.5 2.1 2.3e-43 148.5 1.9 3.4 1 1 1 2 2 2 2 tRNA synthetases class I (M) Ku PF02735.16 VBB28364.1 - 2.6e-13 50.2 0.5 5.3e-13 49.1 0.5 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 VBB28364.1 - 1.5e-11 44.5 0.4 1e-10 41.8 0.1 2.4 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Methyltransf_25 PF13649.6 VBB28364.1 - 3.8e-10 40.3 0.0 2.1e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB28364.1 - 5.1e-10 39.9 0.0 1.3e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain tRNA-synt_1 PF00133.22 VBB28364.1 - 3.2e-09 35.6 0.0 4.8e-05 21.8 0.0 2.6 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 VBB28364.1 - 1.2e-05 25.3 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Ubie_methyltran PF01209.18 VBB28364.1 - 3.3e-05 23.3 0.0 0.00078 18.8 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family tRNA-synt_1e PF01406.19 VBB28364.1 - 0.0008 18.8 0.0 0.023 14.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain VWA_2 PF13519.6 VBB28364.1 - 0.0025 18.4 0.0 0.012 16.3 0.0 2.2 2 0 0 2 2 1 1 von Willebrand factor type A domain PCMT PF01135.19 VBB28364.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 VBB28364.1 - 0.049 12.7 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase tRNA-synt_1f PF01921.18 VBB28364.1 - 0.054 12.4 0.0 0.3 10.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) Methyltransf_31 PF13847.6 VBB28364.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PHD PF00628.29 VBB28365.1 - 7.8e-07 28.9 9.0 1.7e-06 27.8 9.0 1.6 1 0 0 1 1 1 1 PHD-finger zf-CHY PF05495.12 VBB28365.1 - 0.36 11.3 6.2 0.38 11.3 3.7 2.3 2 0 0 2 2 2 0 CHY zinc finger DZR PF12773.7 VBB28365.1 - 7.1 6.7 5.8 83 3.3 1.4 2.7 1 1 1 2 2 2 0 Double zinc ribbon 3Beta_HSD PF01073.19 VBB28366.1 - 2.4e-17 62.9 0.0 3.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 VBB28366.1 - 1.3e-16 60.8 0.0 2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 VBB28366.1 - 1.1e-09 38.3 0.0 0.00045 19.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 VBB28366.1 - 4.4e-07 30.0 0.0 7.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 VBB28366.1 - 4.9e-07 29.5 0.0 1.8e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 VBB28366.1 - 4.1e-06 26.2 0.1 0.00051 19.3 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein Lipoprotein_16 PF03923.13 VBB28366.1 - 0.014 15.1 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized lipoprotein ROQ_II PF18386.1 VBB28368.1 - 0.0076 16.1 0.0 0.05 13.4 0.0 2.3 2 0 0 2 2 2 1 Roquin II domain Pkinase_Tyr PF07714.17 VBB28369.1 - 1.2e-89 300.1 0.1 1.5e-89 299.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB28369.1 - 2.1e-50 171.5 0.5 1.3e-49 168.9 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 VBB28369.1 - 4.3e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 VBB28369.1 - 0.00048 19.5 0.1 0.027 13.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 VBB28369.1 - 0.012 14.9 0.7 0.029 13.7 0.7 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB28369.1 - 0.03 13.1 0.7 0.064 12.0 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 VBB28369.1 - 0.1 12.5 0.2 1.8 8.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP5K PF01504.18 VBB28370.1 - 2.5e-70 236.8 0.0 4.5e-70 236.0 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kinesin PF00225.23 VBB28371.1 - 1e-115 386.2 0.1 1e-115 386.2 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 VBB28371.1 - 4.6e-26 91.6 0.1 4.6e-26 91.6 0.1 1.8 2 0 0 2 2 2 1 Microtubule binding UAA PF08449.11 VBB28373.1 - 3.4e-66 223.5 27.6 4.8e-49 167.2 12.4 2.1 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.20 VBB28373.1 - 0.0054 16.9 30.6 0.0067 16.6 9.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family Calcipressin PF04847.12 VBB28374.1 - 5.2e-33 114.4 0.1 7.2e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Calcipressin Collagen PF01391.18 VBB28375.1 - 3.3e-06 26.8 16.3 4.5e-06 26.3 16.3 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Trimer_CC PF08954.11 VBB28375.1 - 0.14 11.7 0.9 0.29 10.7 0.9 1.5 1 0 0 1 1 1 0 Trimerisation motif DUF4807 PF16065.5 VBB28376.1 - 7.7e-35 119.3 0.8 1.1e-33 115.6 0.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4807) tRNA_m1G_MT PF01746.21 VBB28376.1 - 2.2e-12 47.1 0.0 1e-11 44.9 0.0 2.0 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PseudoU_synth_2 PF00849.22 VBB28376.1 - 5.8e-12 46.0 0.1 5.8e-12 46.0 0.1 2.4 3 0 0 3 3 3 1 RNA pseudouridylate synthase Fringe PF02434.16 VBB28377.1 - 1.9e-15 57.0 0.1 1.1e-14 54.5 0.1 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 VBB28377.1 - 1.4e-05 25.0 0.0 0.0048 16.8 0.1 2.6 2 1 1 3 3 3 2 Galactosyltransferase FGGY_N PF00370.21 VBB28378.1 - 4.7e-13 49.3 0.3 1.3e-11 44.5 0.1 2.3 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 VBB28378.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 VBB28378.1 - 0.0064 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Transposase ROK PF00480.20 VBB28378.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 ROK family EGF_CA PF07645.15 VBB28379.1 - 4.3e-36 122.8 160.3 1.3e-09 38.1 7.9 11.1 10 2 0 10 10 8 6 Calcium-binding EGF domain NIDO PF06119.14 VBB28379.1 - 4.2e-22 78.9 0.2 8.5e-12 45.8 0.0 2.6 2 0 0 2 2 2 2 Nidogen-like EGF_3 PF12947.7 VBB28379.1 - 3.1e-20 72.0 145.4 1.8e-08 34.4 7.6 10.7 10 1 0 10 10 8 7 EGF domain cEGF PF12662.7 VBB28379.1 - 5.3e-17 61.4 80.1 7.9e-06 25.7 1.7 10.1 11 0 0 11 11 11 6 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 VBB28379.1 - 3.1e-05 24.2 16.9 0.00055 20.2 4.4 9.5 7 2 2 9 9 8 5 Pvs28 EGF domain hEGF PF12661.7 VBB28379.1 - 0.00034 21.1 16.3 0.0015 19.1 5.5 13.2 12 1 0 12 12 11 7 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 VBB28379.1 - 0.00094 19.2 109.5 0.0012 18.8 0.2 10.2 10 1 0 10 10 9 6 MSP1 EGF domain 1 EGF PF00008.27 VBB28379.1 - 0.0011 19.2 14.5 0.0021 18.3 3.3 12.3 11 2 1 12 12 11 7 EGF-like domain FXa_inhibition PF14670.6 VBB28379.1 - 0.002 18.4 17.9 0.0026 18.0 5.8 10.6 11 0 0 11 11 8 5 Coagulation Factor Xa inhibitory site TMEM154 PF15102.6 VBB28379.1 - 0.0022 17.9 0.1 0.0022 17.9 0.1 1.7 2 0 0 2 2 2 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 VBB28379.1 - 0.022 14.5 3.2 0.052 13.3 3.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MENTAL PF10457.9 VBB28380.1 - 4.3e-41 140.7 5.3 7.1e-41 140.0 5.3 1.3 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 VBB28380.1 - 3.3e-18 65.9 0.0 5.1e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 START domain CDC27 PF09507.10 VBB28381.1 - 2.9 7.2 46.4 3.5 6.9 46.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Menin PF05053.13 VBB28381.1 - 4.2 5.6 24.4 4.7 5.4 24.4 1.1 1 0 0 1 1 1 0 Menin Usp PF00582.26 VBB28381.1 - 7.5 7.1 18.1 0.85 10.1 1.9 2.1 2 0 0 2 2 2 0 Universal stress protein family BTB PF00651.31 VBB28382.1 - 0.0015 18.7 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Chordopox_A15 PF05846.12 VBB28382.1 - 0.33 11.2 1.6 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Chordopoxvirus A15 protein Pkinase PF00069.25 VBB28383.1 - 2.3e-23 82.9 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28383.1 - 8e-12 45.0 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB28383.1 - 0.013 15.4 0.0 0.8 9.6 0.0 2.5 1 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 VBB28383.1 - 0.026 13.3 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase V_ATPase_I PF01496.19 VBB28384.1 - 0 1068.9 0.5 0 1068.7 0.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Macoilin PF09726.9 VBB28384.1 - 0.12 11.0 0.9 0.19 10.3 0.9 1.2 1 0 0 1 1 1 0 Macoilin family FapA PF03961.13 VBB28384.1 - 0.25 9.9 0.6 0.37 9.4 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 VBB28384.1 - 0.62 10.8 4.1 18 6.2 1.3 2.8 2 0 0 2 2 2 0 Occludin homology domain FlaC_arch PF05377.11 VBB28384.1 - 2.5 8.6 5.6 1.2 9.6 1.8 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SIR2 PF02146.17 VBB28385.1 - 1.1e-60 204.6 0.0 1.8e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 VBB28385.1 - 0.0095 15.7 0.0 0.034 13.9 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 VBB28385.1 - 0.027 14.2 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PDZ_6 PF17820.1 VBB28386.1 - 4.4e-08 32.9 0.0 3.8e-07 29.8 0.0 2.5 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 VBB28386.1 - 2.1e-07 31.2 0.0 4.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB28386.1 - 1.1e-05 25.6 0.0 3.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 VBB28386.1 - 0.0073 16.2 0.1 0.043 13.8 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain MMM1 PF10296.9 VBB28386.1 - 0.012 14.7 0.0 0.012 14.7 0.0 2.0 2 1 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 HA2 PF04408.23 VBB28387.1 - 1e-17 64.4 0.0 1e-17 64.4 0.0 3.8 4 1 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 VBB28387.1 - 1.6e-11 44.5 0.0 3.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB28387.1 - 3.8e-07 30.0 0.1 9.1e-07 28.8 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 VBB28387.1 - 7.3e-06 26.3 0.0 2.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 VBB28387.1 - 0.00046 20.0 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 VBB28387.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 VBB28387.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 VBB28387.1 - 0.034 13.2 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 VBB28387.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 VBB28387.1 - 0.081 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 VBB28387.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.6 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 VBB28387.1 - 0.46 11.0 0.0 0.46 11.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter TB2_DP1_HVA22 PF03134.19 VBB28388.1 - 4.5e-26 90.6 11.0 7.3e-26 89.9 11.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2226 PF09987.9 VBB28388.1 - 0.007 15.7 0.1 0.0086 15.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2226) Smim3 PF17307.2 VBB28388.1 - 0.086 12.3 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Small integral membrane protein 3 Mg_trans_NIPA PF05653.14 VBB28389.1 - 9.6e-123 409.0 20.5 1.1e-122 408.8 20.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 VBB28389.1 - 3.3e-06 27.3 4.3 3.3e-06 27.3 4.3 3.5 3 1 0 3 3 3 1 EamA-like transporter family DUF5383 PF17355.2 VBB28389.1 - 1.1 9.6 5.8 4 7.8 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5383) DUF5345 PF17280.2 VBB28389.1 - 1.6 8.8 5.7 24 5.0 1.3 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) YlaC PF10777.9 VBB28389.1 - 2.7 7.8 7.4 2.7 7.8 1.2 2.5 2 0 0 2 2 2 0 Inner membrane protein YlaC ATP_bind_1 PF03029.17 VBB28390.1 - 2.3e-76 256.8 0.2 3.4e-76 256.2 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 VBB28390.1 - 3.6e-05 23.4 0.0 0.00048 19.7 0.0 2.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 VBB28390.1 - 0.00048 20.6 0.0 0.0012 19.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 VBB28390.1 - 0.00053 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 VBB28390.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 VBB28390.1 - 0.0025 17.7 1.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase MeaB PF03308.16 VBB28390.1 - 0.0035 16.4 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 VBB28390.1 - 0.0049 16.4 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 VBB28390.1 - 0.0068 16.7 0.0 0.053 13.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 VBB28390.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 VBB28390.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 VBB28390.1 - 0.023 14.3 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FeoB_N PF02421.18 VBB28390.1 - 0.025 14.1 0.0 0.095 12.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 VBB28390.1 - 0.03 14.9 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 VBB28390.1 - 0.032 14.1 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 VBB28390.1 - 0.043 13.4 0.4 1.1 8.9 0.1 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 VBB28390.1 - 0.044 13.5 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Chlorovi_GP_rpt PF06598.11 VBB28390.1 - 0.054 13.6 0.4 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat DUF87 PF01935.17 VBB28390.1 - 0.08 13.0 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 VBB28390.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 VBB28390.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DASH_Dad3 PF08656.10 VBB28390.1 - 0.13 12.4 1.5 0.4 10.8 1.5 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 PRK PF00485.18 VBB28390.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Rep_fac-A_C PF08646.10 VBB28391.1 - 1.9e-27 95.8 2.1 3.6e-27 94.9 1.4 1.8 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 VBB28391.1 - 8.6e-20 70.5 0.0 1.4e-18 66.6 0.1 2.6 3 0 0 3 3 3 1 Replication protein A OB domain BRCA2 PF00634.18 VBB28391.1 - 2.8e-07 30.1 0.1 8.8e-07 28.5 0.1 1.9 1 0 0 1 1 1 1 BRCA2 repeat tRNA_anti-codon PF01336.25 VBB28391.1 - 1.6e-05 24.8 0.6 0.0054 16.7 0.0 3.7 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain FAM35_C PF15793.5 VBB28391.1 - 0.028 13.8 0.2 0.054 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein family FAM35, C-terminal DUF3127 PF11325.8 VBB28391.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) A2L_zn_ribbon PF08792.10 VBB28391.1 - 0.087 12.6 2.8 0.25 11.1 2.8 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF3942 PF13078.6 VBB28391.1 - 0.099 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) Prok-RING_1 PF14446.6 VBB28391.1 - 0.13 12.2 0.3 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 VBB28391.1 - 0.14 12.5 0.8 0.34 11.2 0.8 1.7 1 0 0 1 1 1 0 C1 domain Glycos_transf_2 PF00535.26 VBB28392.1 - 5.2e-23 81.7 0.6 1.5e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB28392.1 - 1.9e-11 44.3 1.0 4.1e-11 43.2 1.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 VBB28392.1 - 5.8e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 VBB28392.1 - 0.0068 15.9 0.0 0.019 14.5 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 VBB28392.1 - 0.015 15.2 0.1 0.25 11.2 0.1 2.4 1 1 0 1 1 1 0 Glycosyltransferase like family 2 PBD PF00786.28 VBB28393.1 - 6.4e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Sec7 PF01369.20 VBB28394.1 - 5.5e-62 208.7 0.0 1.2e-61 207.6 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 VBB28394.1 - 8.3e-26 90.8 3.9 8.3e-26 90.8 3.9 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 VBB28394.1 - 9.3e-05 22.2 0.4 0.3 11.0 0.0 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Peptidase_S24 PF00717.23 VBB28395.1 - 9.4e-09 35.1 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 VBB28395.1 - 0.0054 16.5 0.0 0.045 13.6 0.0 2.4 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 TUDOR PF00567.24 VBB28395.1 - 0.035 14.1 0.2 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Tudor domain DUF1908 PF08926.11 VBB28395.1 - 0.063 12.4 0.7 0.73 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) BUD22 PF09073.10 VBB28397.1 - 0.021 14.2 48.7 0.029 13.7 48.7 1.2 1 0 0 1 1 1 0 BUD22 CRT10 PF08728.10 VBB28397.1 - 4.3 5.4 12.1 5.5 5.0 12.1 1.1 1 0 0 1 1 1 0 CRT10 LAP1C PF05609.12 VBB28397.1 - 9.7 5.2 27.6 14 4.6 27.6 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) UCH PF00443.29 VBB28398.1 - 1e-47 162.8 4.4 3.9e-47 160.9 0.4 3.0 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB28398.1 - 1.1e-24 87.6 0.0 7.4e-24 84.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Myelin_PLP PF01275.19 VBB28399.1 - 1.9e-08 34.5 6.4 2.2e-08 34.3 6.4 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF1948 PF09185.10 VBB28399.1 - 0.086 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) SMN PF06003.12 VBB28400.1 - 2.5 7.3 7.8 3.9 6.6 7.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TRM PF02005.16 VBB28401.1 - 8.8e-134 446.4 1.0 1.2e-133 445.9 1.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 VBB28401.1 - 2.8e-05 23.9 0.1 7.6e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 VBB28401.1 - 2.8e-05 23.9 0.1 6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 VBB28401.1 - 4.7e-05 23.0 0.0 9.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 VBB28401.1 - 0.00014 21.0 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 VBB28401.1 - 0.00053 20.7 0.0 0.0017 19.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 VBB28401.1 - 0.0038 16.9 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 VBB28401.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 VBB28401.1 - 0.023 14.2 0.8 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 VBB28401.1 - 0.027 13.9 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 VBB28401.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 VBB28401.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 VBB28401.1 - 0.079 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 VBB28401.1 - 0.099 12.0 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-ribbon_3 PF13248.6 VBB28402.1 - 0.045 13.2 1.1 2.5 7.6 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 VBB28402.1 - 1.6 9.3 11.1 2.1 8.9 5.6 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-IS66 PF13005.7 VBB28402.1 - 2.6 8.5 6.2 26 5.3 0.1 2.9 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Integrase_H2C2 PF17921.1 VBB28403.1 - 1.1e-14 54.2 0.2 2.7e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB28403.1 - 7.9e-05 22.8 1.5 0.00019 21.5 0.0 2.3 3 0 0 3 3 3 1 H2C2 zinc finger Myb_DNA-bind_3 PF12776.7 VBB28403.1 - 0.047 14.7 0.5 1.8 9.6 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DZR PF12773.7 VBB28403.1 - 0.067 13.2 1.9 0.2 11.7 0.5 2.2 2 0 0 2 2 2 0 Double zinc ribbon RNHCP PF12647.7 VBB28403.1 - 0.3 11.1 1.6 20 5.3 0.5 2.8 2 1 1 3 3 3 0 RNHCP domain C1_4 PF07975.12 VBB28403.1 - 0.37 11.1 3.3 0.25 11.6 0.9 2.0 2 0 0 2 2 2 0 TFIIH C1-like domain Mut7-C PF01927.16 VBB28403.1 - 1.5 8.9 4.4 2.6 8.1 2.1 2.6 2 1 0 2 2 2 0 Mut7-C RNAse domain TFIIS_C PF01096.18 VBB28403.1 - 1.7 8.5 5.7 11 6.0 0.1 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-TFIIB PF13453.6 VBB28403.1 - 2 7.8 4.0 16 4.9 0.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger Motile_Sperm PF00635.26 VBB28404.1 - 6.7e-19 67.8 0.0 7.9e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain IL17R_fnIII_D1 PF16556.5 VBB28404.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 G-patch PF01585.23 VBB28405.1 - 5.5e-17 61.4 1.5 1e-16 60.5 1.5 1.5 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 VBB28405.1 - 1.1e-11 44.5 18.0 2.3e-11 43.5 18.0 1.5 1 0 0 1 1 1 1 OCRE domain G-patch_2 PF12656.7 VBB28405.1 - 5.6e-07 29.6 0.6 1.4e-06 28.3 0.6 1.7 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 VBB28405.1 - 0.0018 18.6 0.0 0.0044 17.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain HSP20 PF00011.21 VBB28406.1 - 2.5e-13 50.0 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family MRG PF05712.13 VBB28407.1 - 3e-43 147.4 0.2 5.1e-43 146.7 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 VBB28407.1 - 4.4e-08 32.9 0.9 1.6e-07 31.1 0.9 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 VBB28407.1 - 0.0075 15.9 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain CBM_19 PF03427.13 VBB28408.1 - 0.11 12.5 2.2 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Hydrolase PF00702.26 VBB28409.1 - 8.2e-49 166.7 0.7 1.5e-48 165.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 VBB28409.1 - 1.5e-47 161.4 2.5 1.5e-47 161.4 2.5 3.1 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 VBB28409.1 - 1.4e-23 83.1 5.2 1.4e-13 51.1 0.5 4.1 4 0 0 4 4 4 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 VBB28409.1 - 0.002 17.9 1.0 0.002 17.9 1.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase RhoGAP PF00620.27 VBB28410.1 - 5e-46 156.3 0.0 9.4e-45 152.1 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain PH_9 PF15410.6 VBB28410.1 - 7.3e-12 45.7 0.1 1.6e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 VBB28410.1 - 2.8e-11 43.9 0.2 6.7e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 PH domain WW PF00397.26 VBB28410.1 - 7.7e-08 32.3 1.0 7.7e-08 32.3 1.0 2.5 3 0 0 3 3 3 1 WW domain PH_11 PF15413.6 VBB28410.1 - 0.0026 18.1 0.9 0.013 15.9 0.3 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1708 PF08101.11 VBB28410.1 - 0.012 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) MTS PF05175.14 VBB28411.1 - 1.4e-14 54.0 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 VBB28411.1 - 4.7e-12 45.9 0.4 6.5e-12 45.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 VBB28411.1 - 1.2e-10 41.4 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 VBB28411.1 - 2.6e-07 31.2 0.0 4.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 VBB28411.1 - 4.5e-07 29.8 0.0 6.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 VBB28411.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 VBB28411.1 - 0.00057 19.2 0.0 0.00093 18.5 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 VBB28411.1 - 0.0007 20.2 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 VBB28411.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 VBB28411.1 - 0.0014 18.6 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 VBB28411.1 - 0.002 17.8 0.1 0.0032 17.1 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF43 PF01861.16 VBB28411.1 - 0.0022 17.2 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Met_10 PF02475.16 VBB28411.1 - 0.0047 16.7 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Spermine_synth PF01564.17 VBB28411.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_12 PF08242.12 VBB28411.1 - 0.02 15.6 0.0 0.039 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 VBB28411.1 - 0.078 12.3 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_9 PF08003.11 VBB28411.1 - 0.099 11.5 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 VBB28411.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain FF PF01846.19 VBB28412.1 - 0.11 12.7 0.1 1.3 9.3 0.2 2.3 2 0 0 2 2 2 0 FF domain ShK PF01549.24 VBB28413.1 - 2e-19 69.8 70.0 7e-05 23.3 5.2 5.2 5 0 0 5 5 5 5 ShK domain-like RRM_1 PF00076.22 VBB28414.1 - 7.3e-36 121.8 0.0 3.1e-17 62.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 VBB28414.1 - 1.2e-23 83.9 1.0 2.2e-23 83.2 0.1 1.9 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RSRP PF17069.5 VBB28414.1 - 0.015 14.9 74.6 0.038 13.6 74.6 1.7 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RRM_occluded PF16842.5 VBB28414.1 - 0.031 14.1 0.0 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_5 PF13893.6 VBB28414.1 - 0.22 11.1 0.0 1.7 8.2 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF936 PF06075.12 VBB28414.1 - 0.73 8.7 24.5 1 8.2 24.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF5565 PF17720.1 VBB28416.1 - 0.013 14.4 0.2 0.015 14.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) DUF2011 PF09428.10 VBB28416.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) tRNA_Me_trans PF03054.16 VBB28417.1 - 3.9e-102 341.7 0.0 4.7e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 VBB28417.1 - 3.1e-10 40.0 0.0 9.6e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 VBB28417.1 - 5.8e-06 25.6 0.0 0.00033 19.8 0.0 2.2 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 VBB28417.1 - 0.01 15.3 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC SRCR PF00530.18 VBB28417.1 - 0.042 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Asn_synthase PF00733.21 VBB28417.1 - 0.075 12.7 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.20 VBB28417.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.7 1 1 0 1 1 1 0 PP-loop family SapB_2 PF03489.17 VBB28417.1 - 0.86 9.8 3.5 9.4 6.4 0.1 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 KN_motif PF12075.8 VBB28418.1 - 0.2 11.5 1.5 0.56 10.1 0.1 2.5 3 0 0 3 3 3 0 KN motif SWIM PF04434.17 VBB28419.1 - 0.014 15.0 0.2 0.033 13.9 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger CG-1 PF03859.16 VBB28419.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 CG-1 domain RFX_DNA_binding PF02257.15 VBB28420.1 - 3.8e-33 113.9 0.1 9e-33 112.7 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain DUF3510 PF12022.8 VBB28420.1 - 0.1 13.0 0.9 0.35 11.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Pkinase PF00069.25 VBB28422.1 - 9.2e-22 77.7 0.0 3.2e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28422.1 - 2.9e-09 36.6 0.0 7.6e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB28422.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PKD_channel PF08016.12 VBB28423.1 - 4.8e-11 42.0 12.9 4.8e-11 42.0 12.9 1.7 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 VBB28423.1 - 0.00039 19.7 28.8 0.001 18.3 28.8 1.7 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 VBB28424.1 - 7e-12 45.8 0.1 3.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB28424.1 - 1.3e-10 40.5 0.1 0.00021 21.5 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat GPCR_chapero_1 PF11904.8 VBB28424.1 - 1.2e-09 38.1 0.2 1.5e-09 37.7 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank PF00023.30 VBB28424.1 - 8.6e-09 35.5 0.1 2.8e-06 27.5 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 VBB28424.1 - 3.1e-07 30.8 0.1 0.00066 20.2 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB28424.1 - 6.2e-07 29.6 0.2 4e-05 23.8 0.1 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) HMG_box PF00505.19 VBB28425.1 - 8.8e-37 125.4 12.8 1.5e-22 79.7 3.0 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB28425.1 - 5.3e-33 113.4 13.3 4.5e-17 62.4 2.7 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 VBB28425.1 - 0.0053 16.7 0.3 0.0053 16.7 0.3 2.8 3 1 0 3 3 3 2 HMG (high mobility group) box 5 Ccdc124 PF06244.12 VBB28425.1 - 0.056 14.0 5.9 0.027 15.0 3.6 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF1289 PF06945.13 VBB28425.1 - 0.31 10.9 1.1 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) NACHT_N PF17100.5 VBB28426.1 - 2.6 7.8 5.8 0.93 9.3 0.1 3.1 3 1 1 4 4 4 0 N-terminal domain of NWD NACHT-NTPase SOAR PF16533.5 VBB28427.1 - 5.3e-26 90.5 0.1 5.3e-26 90.5 0.1 3.2 2 1 0 2 2 2 1 STIM1 Orai1-activating region SAM_2 PF07647.17 VBB28427.1 - 8.4e-08 32.2 0.0 1.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 VBB28427.1 - 2.7e-06 27.7 0.0 6.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_1 PF00076.22 VBB28427.1 - 1.2e-05 25.0 0.0 3.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ly49 PF08391.10 VBB28427.1 - 3.8 7.9 6.9 1.1 9.7 1.4 2.7 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region OSTbeta PF15048.6 VBB28427.1 - 9.4 6.4 8.8 0.94 9.6 2.0 2.6 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein Rad60-SLD PF11976.8 VBB28428.1 - 3.7e-14 52.3 1.3 2.5e-13 49.6 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 VBB28428.1 - 0.00012 21.7 0.3 0.00036 20.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family DnaJ PF00226.31 VBB28429.1 - 3.5e-19 68.7 3.3 3.5e-19 68.7 3.3 2.0 3 0 0 3 3 3 1 DnaJ domain Ras PF00071.22 VBB28430.1 - 2.7e-40 137.6 0.0 1.8e-37 128.4 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 VBB28430.1 - 9.3e-30 103.3 0.0 1.2e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28430.1 - 6.3e-09 35.5 0.0 8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB28430.1 - 0.00017 21.7 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 VBB28430.1 - 0.0015 18.9 0.1 0.0073 16.7 0.1 1.9 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 VBB28430.1 - 0.0048 16.6 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 VBB28430.1 - 0.006 16.0 0.0 0.0074 15.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 VBB28430.1 - 0.026 14.0 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 VBB28430.1 - 0.035 13.6 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 VBB28430.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin ArgoMid PF16487.5 VBB28430.1 - 0.04 14.2 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Mid domain of argonaute AAA_33 PF13671.6 VBB28430.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB28430.1 - 0.088 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 VBB28430.1 - 0.091 12.8 0.1 0.22 11.6 0.1 1.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 VBB28430.1 - 0.2 10.8 0.4 2.1 7.4 0.1 2.0 1 1 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 VBB28430.1 - 0.25 10.8 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DKCLD PF08068.12 VBB28431.1 - 2.2e-32 110.9 0.1 1e-31 108.8 0.2 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 VBB28431.1 - 1.5e-23 83.8 0.5 9.2e-21 74.8 0.5 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 VBB28431.1 - 4.4e-21 74.8 0.2 8.8e-21 73.8 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 VBB28431.1 - 1.8e-18 66.3 1.2 3.1e-18 65.5 1.2 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 VBB28431.1 - 0.0017 18.6 0.1 0.0048 17.1 0.1 1.8 1 0 0 1 1 1 1 UPF0113 PUA domain DUF1899 PF08953.11 VBB28432.1 - 9.3e-28 95.9 0.1 1.9e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 VBB28432.1 - 1.8e-16 59.7 0.1 3.5e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 VBB28432.1 - 8.1e-15 55.0 1.7 0.0029 18.4 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28432.1 - 1.8e-06 28.2 0.7 0.11 12.8 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 VBB28432.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain HLH PF00010.26 VBB28434.1 - 9.9e-17 60.6 0.8 1.8e-16 59.8 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ras PF00071.22 VBB28435.1 - 6.9e-58 194.8 0.5 7.9e-58 194.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB28435.1 - 9.3e-22 77.5 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28435.1 - 1.1e-09 38.0 0.1 1.2e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB28435.1 - 5.1e-06 26.2 0.5 1.6e-05 24.6 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB28435.1 - 8.7e-05 22.6 0.1 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB28435.1 - 0.0014 18.5 2.8 0.39 10.6 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 VBB28435.1 - 0.0032 16.7 0.1 0.78 8.8 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit F-actin_cap_A PF01267.17 VBB28436.1 - 3.5e-76 256.2 7.1 9.7e-60 202.2 2.1 3.2 2 1 1 3 3 3 3 F-actin capping protein alpha subunit S1FA PF04689.13 VBB28436.1 - 0.14 12.3 0.2 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 DNA binding protein S1FA DENN PF02141.21 VBB28437.1 - 1.3e-45 155.7 1.9 9e-44 149.7 0.3 2.6 3 0 0 3 3 3 2 DENN (AEX-3) domain uDENN PF03456.18 VBB28437.1 - 8.8e-14 52.0 0.8 2.1e-13 50.8 0.4 2.0 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 VBB28437.1 - 1.3e-12 47.5 9.8 3.2e-12 46.2 9.8 1.7 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 VBB28437.1 - 0.00084 19.5 0.0 0.0058 16.8 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 VBB28437.1 - 0.074 13.3 0.0 0.48 10.8 0.0 2.4 2 0 0 2 2 2 0 PPR repeat MH1 PF03165.16 VBB28438.1 - 1.4e-10 41.3 2.2 1e-09 38.5 0.1 2.4 1 1 1 2 2 2 1 MH1 domain HTH_29 PF13551.6 VBB28438.1 - 0.043 13.8 0.1 0.12 12.4 0.2 1.7 2 0 0 2 2 2 0 Winged helix-turn helix dsrm PF00035.26 VBB28439.1 - 9.7e-11 42.2 3.6 0.018 15.8 0.0 3.6 3 0 0 3 3 3 3 Double-stranded RNA binding motif WW PF00397.26 VBB28439.1 - 0.0041 17.2 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 WW domain PRIMA1 PF16101.5 VBB28439.1 - 5.1 7.2 8.7 13 5.9 8.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TSC22 PF01166.18 VBB28440.1 - 0.0059 16.9 4.9 0.028 14.7 0.2 2.3 1 1 1 2 2 2 1 TSC-22/dip/bun family GIT_CC PF16559.5 VBB28440.1 - 0.066 13.1 1.1 0.32 10.9 0.9 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 VBB28440.1 - 0.15 12.8 0.5 0.25 12.0 0.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Cnn_1N PF07989.11 VBB28440.1 - 0.16 12.2 3.4 0.32 11.2 3.4 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 VBB28440.1 - 0.28 11.0 4.0 0.56 10.0 4.0 1.4 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 VBB28440.1 - 0.92 10.0 6.0 2.2 8.8 6.0 1.6 1 1 0 1 1 1 0 Cell division protein ZapB HD_4 PF13328.6 VBB28441.1 - 1.9e-21 76.4 0.1 3.5e-21 75.6 0.1 1.4 1 1 0 1 1 1 1 HD domain HD PF01966.22 VBB28441.1 - 1.3e-05 25.4 0.1 2.8e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 HD domain DEK_C PF08766.11 VBB28442.1 - 2.3e-10 40.3 0.0 4.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain UBX PF00789.20 VBB28443.1 - 1.5e-18 66.7 0.0 4.6e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 VBB28443.1 - 4.9e-07 29.5 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CCDC71L PF15374.6 VBB28443.1 - 0.096 11.9 10.9 0.11 11.7 10.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L zf-C2H2_3rep PF18868.1 VBB28443.1 - 0.19 12.4 3.3 0.16 12.6 0.9 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats LAP1C PF05609.12 VBB28443.1 - 5.6 5.9 15.4 7 5.6 15.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PV-1 PF06637.11 VBB28443.1 - 7 5.4 18.9 9.9 4.9 18.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Neugrin PF06413.11 VBB28444.1 - 0.076 13.0 1.3 0.12 12.4 1.3 1.2 1 0 0 1 1 1 0 Neugrin DUF1378 PF07125.11 VBB28444.1 - 0.15 12.2 1.4 2.7 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Ribosomal_L4 PF00573.22 VBB28445.1 - 6.6e-38 130.3 1.4 6.7e-38 130.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 VBB28445.1 - 6.5e-23 80.6 1.8 2.1e-22 78.9 1.8 1.9 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain LysM PF01476.20 VBB28446.1 - 7.2e-06 26.0 0.1 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 2 LysM domain RRM_1 PF00076.22 VBB28447.1 - 2.1e-12 46.7 0.0 4.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 VBB28447.1 - 3.2e-09 36.6 0.4 6.8e-09 35.5 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-DNA_Pol PF08996.10 VBB28447.1 - 0.017 14.9 1.7 0.017 14.9 1.7 2.4 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger RNA_bind PF08675.11 VBB28447.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain GRP PF07172.11 VBB28447.1 - 0.098 13.4 18.1 0.23 12.1 18.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_S17e PF00833.18 VBB28448.1 - 3.8e-58 194.7 4.1 4.6e-58 194.5 4.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 FAM76 PF16046.5 VBB28449.1 - 2.4e-39 135.5 44.9 3e-23 82.6 27.9 2.0 1 1 1 2 2 2 2 FAM76 protein CCDC92 PF14916.6 VBB28449.1 - 0.00043 20.0 13.7 0.00072 19.3 5.7 2.9 1 1 2 3 3 3 2 Coiled-coil domain of unknown function DUF2968 PF11180.8 VBB28449.1 - 0.0044 16.7 9.8 0.0069 16.0 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) TPR_12 PF13424.6 VBB28450.1 - 5.1e-16 58.7 3.2 0.0078 16.5 1.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 VBB28450.1 - 5.4e-16 58.9 11.0 5.8e-05 23.5 0.7 6.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 VBB28450.1 - 2.3e-14 52.2 23.8 0.0008 19.3 2.2 9.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 VBB28450.1 - 1e-09 37.8 26.1 0.0002 21.0 2.3 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB28450.1 - 1.8e-08 34.9 3.6 0.0084 16.7 0.0 5.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 VBB28450.1 - 5.6e-06 26.7 16.8 0.053 14.2 1.6 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB28450.1 - 1.2e-05 25.0 20.9 0.14 12.2 1.0 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB28450.1 - 1.3e-05 25.3 26.6 0.00026 21.1 3.0 4.5 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 VBB28450.1 - 2.3e-05 24.3 24.3 0.3 11.4 1.6 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB28450.1 - 0.00013 22.5 1.9 0.28 12.1 0.5 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB28450.1 - 0.0037 17.1 3.8 8.5 6.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 VBB28450.1 - 0.015 15.6 1.0 0.35 11.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat 7TM_GPCR_Srv PF10323.9 VBB28450.1 - 0.022 14.1 1.4 0.05 12.9 1.4 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Fis1_TPR_C PF14853.6 VBB28450.1 - 0.045 13.8 0.1 0.045 13.8 0.1 5.3 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat BRICHOS PF04089.14 VBB28450.1 - 0.077 13.2 0.6 0.24 11.6 0.2 2.0 2 0 0 2 2 2 0 BRICHOS domain TPR_11 PF13414.6 VBB28450.1 - 0.097 12.4 18.8 0.12 12.0 2.2 5.4 5 1 1 6 6 5 0 TPR repeat TAP_C PF03943.13 VBB28450.1 - 0.22 11.2 3.4 4.1 7.1 0.0 4.1 4 0 0 4 4 4 0 TAP C-terminal domain Serpin PF00079.20 VBB28451.1 - 1.5e-58 198.9 0.3 2.1e-58 198.4 0.3 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LIM PF00412.22 VBB28452.1 - 4.8e-60 199.7 51.4 2.5e-16 59.6 5.1 4.3 4 0 0 4 4 4 4 LIM domain DUF3725 PF12523.8 VBB28452.1 - 1.2 9.5 19.5 2.1 8.7 0.6 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3725) Methyltransf_10 PF05971.12 VBB28453.1 - 9.7e-76 254.9 0.0 1.2e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 VBB28453.1 - 6.6e-08 32.3 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 VBB28453.1 - 1.4e-06 28.0 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 VBB28453.1 - 0.00059 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 VBB28453.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 VBB28453.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain EGF PF00008.27 VBB28454.1 - 5.4e-16 58.6 108.5 0.00016 21.9 6.8 13.2 12 3 0 12 12 12 10 EGF-like domain EGF_2 PF07974.13 VBB28454.1 - 0.00041 20.7 7.2 0.00041 20.7 7.2 11.6 11 2 0 11 11 11 5 EGF-like domain hEGF PF12661.7 VBB28454.1 - 0.0029 18.2 4.9 0.0029 18.2 4.9 14.3 13 2 0 13 13 13 4 Human growth factor-like EGF Auto_anti-p27 PF06677.12 VBB28455.1 - 7.6e-12 45.2 3.1 1.2e-11 44.6 3.1 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) T3SS_needle_E PF08988.10 VBB28455.1 - 0.015 15.4 0.4 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle FlaC_arch PF05377.11 VBB28455.1 - 0.058 13.8 0.7 0.15 12.5 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_ME53 PF06061.11 VBB28455.1 - 0.059 12.6 0.1 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Baculoviridae ME53 FANCI_HD2 PF14680.6 VBB28456.1 - 6.9e-33 113.9 4.9 2.3e-32 112.2 4.9 2.0 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_HD1 PF14679.6 VBB28456.1 - 0.00054 19.9 0.5 0.00054 19.9 0.5 3.3 3 0 0 3 3 3 1 FANCI helical domain 1 SprT-like PF10263.9 VBB28456.1 - 0.082 12.8 0.6 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 SprT-like family Polysacc_deac_1 PF01522.21 VBB28457.1 - 1.1e-07 31.8 0.0 6.5e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide deacetylase SCHIP-1 PF10148.9 VBB28458.1 - 2.5e-25 89.5 13.8 2.5e-25 89.5 13.8 3.4 2 2 0 2 2 2 1 Schwannomin-interacting protein 1 EURL PF06937.11 VBB28458.1 - 0.00097 18.6 5.4 0.0021 17.5 5.4 1.5 1 0 0 1 1 1 1 EURL protein Asparaginase_2 PF01112.18 VBB28458.1 - 0.1 11.6 0.7 0.19 10.7 0.7 1.4 1 0 0 1 1 1 0 Asparaginase TMEM237 PF15383.6 VBB28461.1 - 3.2e-31 108.3 0.3 3.9e-31 108.1 0.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 237 7TM_GPCR_Srw PF10324.9 VBB28462.1 - 0.49 9.6 26.4 0.31 10.3 0.9 2.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF1077 PF06417.12 VBB28462.1 - 8.9 6.4 6.7 24 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) SH2 PF00017.24 VBB28463.1 - 1.2e-18 66.9 0.0 1.4e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 SH2 domain PI3K_P85_iSH2 PF16454.5 VBB28463.1 - 6.6e-11 42.1 13.7 1.1e-10 41.4 13.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3829 PF12889.7 VBB28463.1 - 0.051 13.1 5.7 0.076 12.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) GvpL_GvpF PF06386.11 VBB28463.1 - 0.67 9.8 3.9 1.3 8.9 3.9 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF932 PF06067.11 VBB28463.1 - 1.1 9.0 5.9 9.5 5.9 6.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF932) DUF1664 PF07889.12 VBB28463.1 - 1.5 8.9 4.6 1.2 9.1 1.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2951 PF11166.8 VBB28463.1 - 1.5 9.1 6.3 2.3 8.5 0.8 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2951) DUF4624 PF15417.6 VBB28464.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) 5_nucleotid PF05761.14 VBB28465.1 - 6.3e-83 279.2 2.7 7.7e-83 278.9 2.7 1.0 1 0 0 1 1 1 1 5' nucleotidase family USP8_dimer PF08969.11 VBB28465.1 - 0.011 16.0 1.1 0.021 15.0 1.1 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Spectrin PF00435.21 VBB28466.1 - 8.1e-266 861.9 176.0 8.7e-20 71.2 2.4 17.3 17 0 0 17 17 17 17 Spectrin repeat CH PF00307.31 VBB28466.1 - 2.2e-47 159.8 3.0 1.1e-24 86.7 0.0 5.0 5 0 0 5 5 5 2 Calponin homology (CH) domain PH PF00169.29 VBB28466.1 - 5e-13 49.5 1.7 2e-11 44.4 0.0 3.1 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 VBB28466.1 - 1.5e-12 47.9 0.2 2.2e-11 44.1 0.0 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain CAMSAP_CH PF11971.8 VBB28466.1 - 1.1e-06 28.4 0.1 8.7e-05 22.3 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain DUF5616 PF18481.1 VBB28466.1 - 0.37 11.1 6.0 8.9 6.6 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF5616) RhoGAP PF00620.27 VBB28467.1 - 9.2e-27 93.7 0.0 2e-26 92.7 0.0 1.5 2 0 0 2 2 2 1 RhoGAP domain AAA_22 PF13401.6 VBB28467.1 - 0.055 13.7 0.1 0.5 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Histone PF00125.24 VBB28468.1 - 7.9e-24 84.5 1.3 1.1e-23 84.0 1.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB28468.1 - 1e-06 28.9 0.1 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 VBB28468.1 - 0.001 19.5 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 VBB28468.1 - 0.0081 16.2 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein DUF3391 PF11871.8 VBB28468.1 - 0.098 13.2 0.3 0.14 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) 2-ph_phosp PF04029.14 VBB28468.1 - 8.8 5.4 6.4 2.5 7.2 0.2 2.2 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase Histone_H2A_C PF16211.5 VBB28469.1 - 2e-19 69.0 1.8 4.3e-19 68.0 1.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 VBB28469.1 - 4.8e-16 59.3 0.0 5.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB28469.1 - 3.2e-07 30.5 0.0 7.5e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 VBB28470.1 - 5.9e-08 32.8 0.0 7.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 VBB28470.1 - 2.7e-05 24.5 0.1 4.1e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 VBB28470.1 - 0.0001 22.4 0.1 0.00015 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 VBB28470.1 - 0.00011 22.4 0.1 0.00019 21.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB28470.1 - 0.00034 21.0 0.2 0.00048 20.5 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 VBB28470.1 - 0.0048 16.9 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 VBB28470.1 - 0.013 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Dzip-like_N PF13815.6 VBB28471.1 - 0.074 13.0 0.3 0.11 12.5 0.3 1.4 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Baculo_LEF-10 PF07206.11 VBB28471.1 - 0.08 13.1 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) HEAT PF02985.22 VBB28471.1 - 0.14 12.4 0.5 0.58 10.6 0.1 2.1 2 0 0 2 2 2 0 HEAT repeat HEAT PF02985.22 VBB28473.1 - 1.1e-07 31.5 4.6 2.7 8.5 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 VBB28473.1 - 7.2e-07 29.5 0.9 0.011 16.1 0.1 4.2 4 1 0 4 4 4 2 HEAT repeats CMV_1a PF12467.8 VBB28473.1 - 0.061 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Pkinase PF00069.25 VBB28474.1 - 4.9e-39 134.3 0.0 7.3e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28474.1 - 8.7e-13 48.1 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NAP PF00956.18 VBB28475.1 - 0.0049 16.1 0.4 0.0052 16.0 0.4 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) ERM PF00769.19 VBB28475.1 - 0.0068 16.3 3.0 0.0077 16.1 3.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DNA_pol_A PF00476.20 VBB28475.1 - 0.084 11.9 1.4 0.13 11.3 1.5 1.3 1 1 0 1 1 1 0 DNA polymerase family A DUF3915 PF13054.6 VBB28475.1 - 5.7 6.9 11.5 23 5.0 11.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) MORN PF02493.20 VBB28477.1 - 1.3e-15 56.3 35.9 0.001 18.8 1.2 8.2 8 0 0 8 8 8 6 MORN repeat DUF1134 PF06577.12 VBB28477.1 - 0.014 15.1 0.9 0.03 14.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) DUF3303 PF11746.8 VBB28477.1 - 0.02 15.2 0.0 0.084 13.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) RCC1 PF00415.18 VBB28479.1 - 4.2e-23 81.7 0.7 6.3e-13 49.1 0.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB28479.1 - 1.3e-14 53.6 11.1 1.1e-11 44.2 0.6 4.9 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat zf-RRPl_C4 PF17026.5 VBB28479.1 - 0.83 9.8 5.5 0.64 10.1 0.1 2.9 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Pkinase_Tyr PF07714.17 VBB28480.1 - 7.2e-55 186.1 0.8 3.4e-26 92.1 0.1 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 VBB28480.1 - 1.1e-31 110.2 0.5 3.2e-10 39.8 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain SH2 PF00017.24 VBB28480.1 - 2.5e-13 49.9 0.2 4.7e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 SH2 domain MADF_DNA_bdg PF10545.9 VBB28481.1 - 2.7e-16 59.7 0.6 2.7e-16 59.7 0.6 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 VBB28481.1 - 0.00041 20.4 0.4 0.0018 18.3 0.4 2.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 VBB28481.1 - 0.0012 19.2 0.2 0.0012 19.2 0.2 2.7 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain BESS PF02944.20 VBB28481.1 - 0.003 17.3 1.0 0.0066 16.2 1.0 1.5 1 0 0 1 1 1 1 BESS motif ArfGap PF01412.18 VBB28483.1 - 7.9e-35 119.5 0.0 2.4e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 VBB28483.1 - 9.6e-35 120.4 2.2 9.9e-35 120.4 1.0 1.6 2 0 0 2 2 2 1 BAR domain of APPL family Ank_2 PF12796.7 VBB28483.1 - 1.6e-19 70.3 9.2 3.3e-11 43.6 0.9 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 VBB28483.1 - 2.8e-16 59.9 0.1 6.4e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 VBB28483.1 - 2e-13 50.3 0.5 1e-06 28.9 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB28483.1 - 1.1e-09 37.6 0.4 0.0056 17.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 VBB28483.1 - 1.6e-09 38.1 0.4 0.0012 19.4 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 VBB28483.1 - 1.7e-09 37.7 3.2 0.0022 18.4 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeat BAR PF03114.18 VBB28483.1 - 0.042 13.5 0.5 0.098 12.3 0.1 1.7 2 0 0 2 2 2 0 BAR domain PH_11 PF15413.6 VBB28483.1 - 0.069 13.6 3.6 1.7 9.1 1.9 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain Copine PF07002.16 VBB28484.1 - 2.7e-61 206.8 0.0 4.8e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 VBB28484.1 - 5.3e-07 30.0 0.0 9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 VBB28484.1 - 0.0026 18.0 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Zona_pellucida PF00100.23 VBB28485.1 - 6.1e-07 29.5 1.7 9e-07 28.9 1.7 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DnaJ PF00226.31 VBB28486.1 - 3.6e-18 65.4 1.8 3.6e-18 65.4 1.8 2.4 2 0 0 2 2 2 1 DnaJ domain Collagen PF01391.18 VBB28488.1 - 1.1e-23 82.7 101.0 2.8e-10 39.8 32.5 4.7 3 1 1 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28488.1 - 3.2e-19 68.7 0.2 4.4e-19 68.3 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB28489.1 - 6.5e-22 77.1 90.7 1.5e-09 37.4 32.8 4.3 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28489.1 - 7.6e-17 61.1 0.1 1.1e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Pox_G5 PF04599.12 VBB28489.1 - 0.028 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Fam20C PF06702.12 VBB28489.1 - 0.036 13.9 0.1 0.053 13.3 0.1 1.1 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 UPF0564 PF10595.9 VBB28489.1 - 0.12 11.5 6.0 0.16 11.0 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 RRN3 PF05327.11 VBB28489.1 - 0.96 7.9 5.0 1.3 7.5 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ArfGap PF01412.18 VBB28489.1 - 9.3 6.4 8.6 0.23 11.6 0.7 2.3 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf IRS PF02174.17 VBB28491.1 - 2.9e-21 75.2 0.1 4.9e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DnaJ_C PF01556.18 VBB28492.1 - 1.7e-42 145.0 0.1 2.2e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 VBB28492.1 - 4e-28 97.3 2.4 9.5e-28 96.1 2.4 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_C1 PF00112.23 VBB28493.1 - 2.6e-25 89.8 5.0 1.3e-16 61.4 0.6 2.8 1 1 1 2 2 2 2 Papain family cysteine protease PFL-like PF02901.15 VBB28493.1 - 0.0037 16.0 0.0 0.0041 15.8 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Glutaminase PF04960.15 VBB28494.1 - 2.9e-96 322.0 0.0 1.4e-94 316.5 0.0 2.2 1 1 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 VBB28494.1 - 5e-25 87.7 1.1 7.2e-25 87.2 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain Ank_5 PF13857.6 VBB28494.1 - 2e-07 31.2 0.1 7.7e-07 29.3 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB28494.1 - 7.9e-07 29.6 0.0 2.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB28494.1 - 0.00023 21.7 0.0 0.00072 20.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB28494.1 - 0.00068 19.9 0.0 0.006 17.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 VBB28494.1 - 0.0015 18.9 0.0 0.0048 17.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Clat_adaptor_s PF01217.20 VBB28495.1 - 3.9e-26 91.7 0.8 4.9e-26 91.4 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ORC2 PF04084.14 VBB28496.1 - 2.2e-55 187.9 2.1 5.2e-55 186.7 2.1 1.6 1 1 0 1 1 1 1 Origin recognition complex subunit 2 EspA PF03433.13 VBB28496.1 - 0.011 15.6 0.1 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 EspA-like secreted protein DUF745 PF05335.13 VBB28498.1 - 0.004 16.9 9.9 0.004 16.9 9.9 6.9 5 3 3 8 8 8 1 Protein of unknown function (DUF745) Bac_surface_Ag PF01103.23 VBB28498.1 - 0.25 10.8 2.0 0.71 9.3 2.0 1.7 1 0 0 1 1 1 0 Surface antigen LHH PF14411.6 VBB28498.1 - 1.3 9.2 5.6 4.1 7.6 0.3 3.6 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Ribosomal_L29e PF01779.17 VBB28499.1 - 1.7e-22 79.4 15.3 1.7e-22 79.4 15.3 2.0 2 0 0 2 2 2 1 Ribosomal L29e protein family THOC7 PF05615.13 VBB28500.1 - 2.2e-23 83.0 0.1 2.2e-23 83.0 0.1 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 PG_binding_3 PF09374.10 VBB28500.1 - 0.061 13.6 0.8 0.16 12.2 0.5 1.9 1 1 0 1 1 1 0 Predicted Peptidoglycan domain PEPcase PF00311.17 VBB28500.1 - 0.1 10.7 4.9 0.34 8.9 5.4 1.3 1 1 0 1 1 1 0 Phosphoenolpyruvate carboxylase Hemagglutinin PF00509.18 VBB28500.1 - 6.3 5.1 7.4 0.73 8.2 1.2 1.9 1 1 1 2 2 2 0 Haemagglutinin Y_phosphatase PF00102.27 VBB28501.1 - 3.9e-07 29.9 0.0 4.7e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB28501.1 - 2.6e-06 27.3 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB28501.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GNT-I PF03071.15 VBB28502.1 - 1.4e-135 452.5 0.4 1.1e-111 373.7 0.1 2.0 1 1 1 2 2 2 2 GNT-I family Homeodomain PF00046.29 VBB28503.1 - 7.6e-22 76.9 1.3 1.2e-21 76.3 1.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB28503.1 - 0.0073 16.2 0.0 0.032 14.1 0.0 2.1 1 0 0 1 1 1 1 Homeobox KN domain G-patch PF01585.23 VBB28505.1 - 1.8e-16 59.7 1.3 3.8e-16 58.7 1.3 1.6 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 VBB28505.1 - 1.7e-15 56.8 11.1 3.8e-15 55.6 11.1 1.6 1 0 0 1 1 1 1 OCRE domain G-patch_2 PF12656.7 VBB28505.1 - 1.8e-10 40.8 0.2 4.3e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 VBB28505.1 - 4.5e-08 32.8 0.0 0.0012 18.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 VBB28505.1 - 0.014 14.7 5.4 0.035 13.4 5.4 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-C2H2_jaz PF12171.8 VBB28505.1 - 0.078 13.3 0.2 0.24 11.7 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Transformer PF06495.11 VBB28505.1 - 0.093 12.8 32.5 0.25 11.4 32.5 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein Pkinase PF00069.25 VBB28506.1 - 3.7e-46 157.6 0.4 3.7e-46 157.6 0.4 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28506.1 - 1.4e-21 76.9 0.1 4.6e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CHCC PF10276.9 VBB28507.1 - 7.5e-18 64.3 3.3 1.2e-17 63.7 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain Collagen PF01391.18 VBB28508.1 - 2.1e-11 43.4 24.9 3.6e-11 42.6 24.9 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Arm PF00514.23 VBB28509.1 - 4.8e-26 89.9 8.0 6.9e-06 25.9 0.1 8.8 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 VBB28509.1 - 4.8e-05 22.1 0.7 0.061 11.9 0.1 3.4 2 1 2 4 4 4 4 Adaptin N terminal region HEAT_2 PF13646.6 VBB28509.1 - 0.0049 17.2 6.6 3.7 8.0 0.1 5.1 3 2 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 VBB28509.1 - 0.64 10.6 7.5 1.8 9.1 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat Pkinase PF00069.25 VBB28510.1 - 6.2e-66 222.5 0.0 1e-65 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28510.1 - 1.5e-35 122.8 0.0 2.3e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB28510.1 - 1.4e-08 34.4 0.0 8.7e-08 31.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like tRNA-synt_1 PF00133.22 VBB28511.1 - 2.7e-37 128.3 2.8 1.5e-18 66.4 0.4 4.6 2 2 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 VBB28511.1 - 2.6e-24 85.7 0.0 2.5e-19 69.3 0.0 3.7 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 VBB28511.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 VBB28511.1 - 0.02 14.3 0.0 0.46 9.8 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 VBB28511.1 - 0.052 12.5 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) Hexokinase_1 PF00349.21 VBB28512.1 - 1.8e-55 187.9 0.0 2.1e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Hexokinase ArsR PF09824.9 VBB28512.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Ground-like PF04155.18 VBB28513.1 - 4.4e-17 62.5 1.0 6.8e-17 61.9 0.2 1.8 2 0 0 2 2 2 1 Ground-like domain ACOX PF01756.19 VBB28514.1 - 7e-49 165.8 0.1 1.2e-48 165.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 VBB28514.1 - 9e-28 97.3 0.0 2.6e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal zf-rbx1 PF12678.7 VBB28514.1 - 1e-19 70.5 16.7 2.1e-19 69.5 16.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 VBB28514.1 - 2.2e-16 59.7 16.7 7.8e-16 57.9 16.7 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Acyl-CoA_dh_M PF02770.19 VBB28514.1 - 4.5e-13 49.2 0.0 7.9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain zf-RING_2 PF13639.6 VBB28514.1 - 0.0014 19.0 21.9 0.0014 19.0 21.9 2.6 2 1 0 2 2 2 1 Ring finger domain Acyl-CoA_dh_1 PF00441.24 VBB28514.1 - 0.088 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-C3HC4_2 PF13923.6 VBB28514.1 - 0.1 12.5 18.1 0.58 10.0 18.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB28514.1 - 0.2 11.6 16.1 0.55 10.1 16.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB28514.1 - 2.4 8.2 15.1 7 6.7 15.1 1.9 1 1 0 1 1 1 0 zinc-RING finger domain mTERF PF02536.14 VBB28515.1 - 2.4e-16 59.6 2.0 3.6e-11 42.6 0.2 1.9 1 1 1 2 2 2 2 mTERF Tom22 PF04281.13 VBB28516.1 - 7.3e-12 45.3 0.1 8.9e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 UPF0542 PF15086.6 VBB28516.1 - 0.026 14.4 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TIP49 PF06068.13 VBB28517.1 - 2e-163 543.6 0.2 3e-163 543.0 0.2 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain SBF PF01758.16 VBB28517.1 - 2.7e-26 92.5 20.2 5.4e-26 91.5 20.2 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family TIP49_C PF17856.1 VBB28517.1 - 7.1e-22 77.3 1.9 9.6e-22 76.9 0.3 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 VBB28517.1 - 3.6e-12 46.8 1.0 5.8e-07 30.0 0.0 3.9 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 VBB28517.1 - 3.2e-11 43.2 0.1 2.1e-06 27.5 0.0 3.5 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB28517.1 - 1.7e-06 28.4 0.1 0.036 14.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 VBB28517.1 - 0.00014 22.3 0.0 0.0023 18.3 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 VBB28517.1 - 0.00039 20.4 0.1 0.035 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 VBB28517.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB28517.1 - 0.0011 19.5 0.0 0.037 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_lid_2 PF17863.1 VBB28517.1 - 0.0021 17.8 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain Sigma54_activat PF00158.26 VBB28517.1 - 0.0025 17.5 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 VBB28517.1 - 0.0025 18.1 0.4 0.86 9.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 VBB28517.1 - 0.0041 16.5 0.1 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 VBB28517.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 VBB28517.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 VBB28517.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.16 VBB28517.1 - 0.032 13.7 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 VBB28517.1 - 0.035 13.6 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 VBB28517.1 - 0.036 14.1 0.0 8.2 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 VBB28517.1 - 0.059 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 VBB28517.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 VBB28517.1 - 0.094 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TFIID-31kDa PF02291.15 VBB28517.1 - 0.1 12.6 0.3 0.95 9.5 0.1 2.5 3 0 0 3 3 2 0 Transcription initiation factor IID, 31kD subunit DUF1646 PF07854.12 VBB28517.1 - 0.12 11.7 13.9 0.008 15.6 7.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1646) ResIII PF04851.15 VBB28517.1 - 0.12 12.4 0.3 2.6 8.0 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 VBB28517.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 VBB28517.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 VBB28517.1 - 0.15 11.4 0.1 10 5.4 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein Sedlin_N PF04628.13 VBB28518.1 - 2.1e-29 102.3 0.1 2.7e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pmp3 PF01679.17 VBB28518.1 - 1.4e-14 54.0 6.3 2.1e-14 53.4 6.3 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Miff PF05644.11 VBB28519.1 - 1.5e-19 70.8 3.1 1.2e-13 51.3 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff TMEM247 PF15444.6 VBB28519.1 - 0.061 13.4 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 ATP_bind_1 PF03029.17 VBB28522.1 - 1.5e-68 231.2 0.0 1.8e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 VBB28522.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 VBB28522.1 - 0.043 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 VBB28522.1 - 0.052 13.5 0.1 0.26 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 VBB28522.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 VBB28522.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 VBB28522.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_33 PF13671.6 VBB28522.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IBR PF01485.21 VBB28523.1 - 8.1e-20 70.8 51.6 7.2e-15 55.0 4.8 5.0 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 VBB28523.1 - 0.0012 18.7 9.3 0.0012 18.7 9.3 5.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB28523.1 - 0.0092 15.8 7.9 0.0092 15.8 7.9 5.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 VBB28523.1 - 7.3 6.8 12.7 5.5 7.2 0.1 4.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Thioredoxin_6 PF13848.6 VBB28524.1 - 1.3e-48 165.4 0.0 8.3e-40 136.7 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 VBB28524.1 - 3.8e-21 75.0 0.0 9.5e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 VBB28524.1 - 0.00023 20.3 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 VBB28524.1 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 VBB28524.1 - 0.0016 18.7 0.1 0.0083 16.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 VBB28524.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 VBB28524.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Nmad4 PF18756.1 VBB28524.1 - 0.076 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 4 Thioredoxin_2 PF13098.6 VBB28524.1 - 0.14 12.6 0.0 0.45 11.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Phos_pyr_kin PF08543.12 VBB28525.1 - 4.8e-12 45.8 0.0 6.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 VBB28525.1 - 5.1e-11 42.4 0.0 9.7e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SHS2_Rpb7-N PF03876.17 VBB28526.1 - 0.00068 20.0 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GEMIN8 PF15348.6 VBB28527.1 - 3.6e-27 96.2 9.3 4.4e-26 92.6 0.7 2.0 1 1 1 2 2 2 2 Gemini of Cajal bodies-associated protein 8 GKAP PF03359.13 VBB28528.1 - 7.6e-23 81.6 9.4 7.6e-23 81.6 9.4 2.3 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein MscS_TM PF12794.7 VBB28528.1 - 0.96 8.2 3.4 1.8 7.3 3.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SH2_2 PF14633.6 VBB28529.1 - 1.8e-77 259.6 1.8 1.8e-77 259.6 1.8 1.8 2 0 0 2 2 1 1 SH2 domain YqgF PF14639.6 VBB28529.1 - 3e-37 127.7 0.0 6.7e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 VBB28529.1 - 1.2e-33 115.5 0.0 2.8e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 VBB28529.1 - 9.2e-18 64.8 4.6 2.6e-17 63.3 4.6 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 Erf4 PF10256.9 VBB28529.1 - 5.8e-10 39.3 0.2 2.9e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Golgin subfamily A member 7/ERF4 family Tex_N PF09371.10 VBB28529.1 - 2.3e-09 37.2 2.6 0.0031 17.2 0.0 3.5 2 1 1 3 3 3 2 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 VBB28529.1 - 2.6e-07 31.1 0.0 5.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain SH2 PF00017.24 VBB28529.1 - 3.1e-07 30.4 0.1 2.4e-05 24.4 0.1 2.9 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 VBB28529.1 - 5.1e-07 30.5 0.1 2.1e-06 28.5 0.1 2.2 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 VBB28529.1 - 2.1e-05 24.8 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 VBB28529.1 - 0.00048 20.3 0.0 0.0022 18.2 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif GTP_EFTU PF00009.27 VBB28530.1 - 1.1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 VBB28530.1 - 1.4e-05 25.4 0.1 4.7e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 VBB28530.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 VBB28530.1 - 0.055 13.4 0.0 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 ABC_tran PF00005.27 VBB28530.1 - 0.15 12.6 0.1 0.29 11.6 0.1 1.5 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 VBB28530.1 - 0.16 11.7 0.9 18 5.1 0.1 3.4 2 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 VBB28530.1 - 0.26 11.3 0.9 0.59 10.2 0.0 1.9 3 0 0 3 3 3 0 Helicase HerA, central domain Striatin PF08232.12 VBB28531.1 - 1.6e-40 139.3 7.4 1.6e-40 139.3 7.4 3.3 2 2 0 2 2 2 1 Striatin family WD40 PF00400.32 VBB28531.1 - 1e-31 108.5 6.4 7.3e-07 29.8 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28531.1 - 1.7e-07 31.4 0.1 0.019 15.2 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 VBB28531.1 - 2.1e-05 23.5 0.0 0.11 11.2 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 VBB28531.1 - 0.00093 18.0 0.4 0.67 8.5 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 MAM PF00629.23 VBB28533.1 - 4.9e-07 29.8 0.1 6.5e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF5332 PF17266.2 VBB28535.1 - 1.5e-42 144.8 21.5 1.5e-42 144.8 21.5 1.9 1 1 1 2 2 2 2 Family of unknown function (DUF5332) QVR PF17064.5 VBB28536.1 - 0.27 11.5 3.2 0.7 10.2 0.6 2.1 2 0 0 2 2 2 0 Sleepless protein NADH_B2 PF14813.6 VBB28537.1 - 1.7e-17 62.9 0.4 1.7e-17 62.9 0.4 1.7 2 0 0 2 2 2 1 NADH dehydrogenase 1 beta subcomplex subunit 2 ABC_tran PF00005.27 VBB28538.1 - 1.2e-17 64.7 0.1 1.8e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 VBB28538.1 - 0.0049 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 VBB28538.1 - 0.006 16.3 0.1 0.0095 15.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 VBB28538.1 - 0.025 14.5 0.9 0.089 12.7 0.9 2.2 1 1 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 VBB28538.1 - 0.05 13.4 1.5 0.055 13.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 VBB28538.1 - 0.068 13.5 0.1 0.18 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 VBB28538.1 - 0.087 13.2 0.2 0.28 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 VBB28538.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 VBB28538.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 VBB28538.1 - 0.098 12.8 0.1 0.25 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 VBB28538.1 - 0.14 12.6 0.1 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 VBB28538.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 VBB28538.1 - 0.16 11.7 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 VBB28538.1 - 0.6 10.6 4.5 0.22 12.0 0.7 2.0 2 1 0 2 2 2 0 AAA domain ARD PF03079.14 VBB28539.1 - 3.8e-27 95.4 0.1 4e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 VBB28539.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Cupin domain ABC_tran PF00005.27 VBB28540.1 - 8.1e-07 29.6 0.1 1.8e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 ABC transporter USP7_C2 PF14533.6 VBB28541.1 - 2e-52 177.9 0.7 5.5e-52 176.5 0.5 1.8 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 VBB28541.1 - 6.5e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Lipocalin_2 PF08212.12 VBB28542.1 - 0.11 12.4 0.0 9 6.2 0.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain Lipocalin_2 PF08212.12 VBB28543.1 - 0.0022 17.9 2.0 0.0084 16.0 2.0 1.9 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 VBB28543.1 - 0.014 15.6 0.6 0.043 14.0 0.6 1.8 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 VBB28544.1 - 0.00095 19.1 0.0 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin_2 PF08212.12 VBB28545.1 - 0.0054 16.7 0.1 0.047 13.6 0.1 2.1 1 1 0 1 1 1 1 Lipocalin-like domain DUF4003 PF13170.6 VBB28545.1 - 0.075 12.4 1.0 0.094 12.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) RabGAP-TBC PF00566.18 VBB28546.1 - 5.9e-33 114.3 4.1 6.6e-32 110.9 4.5 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 VBB28546.1 - 1e-17 64.4 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28546.1 - 1.1e-11 44.5 0.0 2.4e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 VBB28546.1 - 2.4e-10 40.9 0.0 5.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain HBS1_N PF08938.10 VBB28546.1 - 0.1 12.9 0.3 4 7.8 0.1 2.5 2 0 0 2 2 2 0 HBS1 N-terminus DUF4629 PF15442.6 VBB28547.1 - 0.02 15.1 0.2 0.03 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) GDP_Man_Dehyd PF16363.5 VBB28550.1 - 9.5e-48 163.3 0.2 2.1e-42 145.7 0.0 3.2 2 1 1 3 3 3 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 VBB28550.1 - 4.6e-47 160.5 0.6 1.6e-40 139.1 0.4 3.4 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 VBB28550.1 - 3.6e-13 49.2 1.1 1.3e-06 27.6 0.0 3.2 2 1 1 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 VBB28550.1 - 7.1e-13 48.3 0.5 1.7e-08 34.0 0.0 3.9 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 VBB28550.1 - 9.4e-13 47.9 0.0 2.4e-09 36.7 0.0 2.6 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 VBB28550.1 - 2.6e-11 43.2 0.0 1.8e-08 33.9 0.0 3.5 3 1 1 4 4 4 1 Male sterility protein adh_short PF00106.25 VBB28550.1 - 0.043 13.3 0.0 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 short chain dehydrogenase Fe_hyd_SSU PF02256.17 VBB28550.1 - 0.1 12.7 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 Iron hydrogenase small subunit Sec2p PF06428.11 VBB28551.1 - 2.4e-06 27.4 1.7 4.6e-06 26.5 1.7 1.5 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p IFT57 PF10498.9 VBB28551.1 - 0.016 14.2 0.5 0.029 13.3 0.5 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Matrilin_ccoil PF10393.9 VBB28551.1 - 0.024 14.5 3.2 0.44 10.5 0.2 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Lipoprotein_20 PF13942.6 VBB28551.1 - 0.039 13.9 0.8 0.064 13.2 0.8 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Tropomyosin_1 PF12718.7 VBB28551.1 - 0.049 13.8 4.0 0.086 13.0 4.0 1.3 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.20 VBB28551.1 - 0.063 12.6 7.1 0.13 11.6 7.1 1.4 1 0 0 1 1 1 0 Tropomyosin B56 PF01603.20 VBB28551.1 - 0.063 12.2 0.4 0.11 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DSPc PF00782.20 VBB28552.1 - 1.6e-25 89.4 0.0 2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB28552.1 - 0.00044 19.9 0.1 0.00054 19.6 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 VBB28552.1 - 0.0017 18.5 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 VBB28552.1 - 0.1 12.1 0.1 0.32 10.6 0.0 1.9 2 1 0 2 2 2 0 Tyrosine phosphatase family Sep15_SelM PF08806.11 VBB28552.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 1 1 0 1 1 1 0 Sep15/SelM redox domain DUF442 PF04273.13 VBB28552.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 Putative phosphatase (DUF442) LMBR1 PF04791.16 VBB28553.1 - 5.9e-141 470.9 24.3 6.8e-141 470.7 24.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Tim17 PF02466.19 VBB28554.1 - 1.1e-24 87.0 4.7 1.4e-24 86.6 4.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 VBB28554.1 - 1.7 8.5 11.0 0.15 11.8 5.0 2.0 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 VBB28554.1 - 2.8 8.0 11.0 0.16 12.0 4.5 2.0 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.9 VBB28554.1 - 8.8 6.5 10.0 13 6.0 0.3 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide V-set PF07686.17 VBB28555.1 - 0.03 14.5 0.1 0.038 14.2 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain RTC PF01137.21 VBB28556.1 - 5.9e-45 153.2 0.0 8.8e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 VBB28556.1 - 6e-29 100.6 0.0 1.8e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RNase_H2_suC PF08615.11 VBB28556.1 - 4.3e-12 46.4 0.1 1.4e-09 38.3 0.0 2.3 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WD-3 PF09765.9 VBB28556.1 - 0.0035 16.7 0.3 0.068 12.5 0.3 2.4 3 0 0 3 3 3 1 WD-repeat region Lsm_interact PF05391.11 VBB28556.1 - 0.16 11.5 0.6 0.34 10.5 0.6 1.6 1 0 0 1 1 1 0 Lsm interaction motif Torsin PF06309.11 VBB28557.1 - 3.8e-46 156.3 0.4 6.3e-46 155.6 0.4 1.4 1 0 0 1 1 1 1 Torsin AAA_14 PF13173.6 VBB28557.1 - 0.0076 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 VBB28557.1 - 0.011 16.0 0.1 0.68 10.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 VBB28557.1 - 0.017 15.5 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 VBB28557.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) VirE PF05272.11 VBB28557.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E Type_III_YscX PF09474.10 VBB28557.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) DUF3384 PF11864.8 VBB28558.1 - 5.4e-50 170.7 15.2 6.9e-50 170.3 9.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 VBB28558.1 - 1.6e-37 129.5 1.1 4.7e-29 101.6 0.3 2.7 2 0 0 2 2 2 2 Tuberin Rap_GAP PF02145.15 VBB28558.1 - 3.9e-26 91.7 0.0 1.3e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP DUF3361 PF11841.8 VBB28558.1 - 0.0078 16.2 0.9 7 6.6 0.1 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) HEAT PF02985.22 VBB28559.1 - 3.6e-13 48.5 8.6 0.00027 20.9 0.1 7.1 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 VBB28559.1 - 5e-06 26.8 0.1 0.0053 17.1 0.0 4.2 4 2 0 4 4 4 1 HEAT repeats PrkA PF06798.12 VBB28559.1 - 0.024 14.3 8.5 0.26 10.9 5.2 2.5 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain Arm PF00514.23 VBB28559.1 - 0.03 14.4 0.7 1 9.5 0.1 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 VBB28559.1 - 0.21 12.2 2.4 43 4.7 0.1 4.6 3 1 1 4 4 4 0 HEAT-like repeat DUF3385 PF11865.8 VBB28559.1 - 0.39 10.6 3.7 32 4.4 0.1 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF3385) CD52 PF15116.6 VBB28560.1 - 0.089 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen fn3 PF00041.21 VBB28561.1 - 0 1482.4 58.4 3.1e-17 62.7 0.0 31.8 31 0 0 31 31 31 31 Fibronectin type III domain I-set PF07679.16 VBB28561.1 - 0 1282.4 37.2 1.5e-22 79.4 0.0 35.1 39 0 0 39 39 36 26 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB28561.1 - 1.3e-242 785.1 31.5 1.9e-14 54.0 0.0 29.2 30 0 0 30 30 27 26 Immunoglobulin domain Ig_2 PF13895.6 VBB28561.1 - 1.2e-136 445.3 26.7 7.4e-10 39.0 0.2 27.0 26 0 0 26 26 26 24 Immunoglobulin domain ig PF00047.25 VBB28561.1 - 3.8e-122 398.8 38.7 4.8e-11 42.7 0.1 25.2 26 0 0 26 26 24 20 Immunoglobulin domain Pkinase PF00069.25 VBB28561.1 - 7.7e-70 235.3 0.0 1.2e-69 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pur_ac_phosph_N PF16656.5 VBB28561.1 - 9.3e-51 170.4 22.9 0.23 12.0 0.1 30.0 30 1 0 30 30 30 7 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 VBB28561.1 - 5.7e-41 139.1 41.5 0.02 15.1 0.0 27.7 25 8 0 25 25 25 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 VBB28561.1 - 3.2e-35 121.7 0.0 5.2e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Tissue_fac PF01108.17 VBB28561.1 - 7.5e-30 102.9 0.0 0.64 9.9 0.0 20.3 23 0 0 23 23 22 2 Tissue factor C2-set_2 PF08205.12 VBB28561.1 - 2.1e-26 91.8 17.8 0.37 10.9 0.0 17.1 18 0 0 18 18 16 4 CD80-like C2-set immunoglobulin domain Y_Y_Y PF07495.13 VBB28561.1 - 4.1e-21 74.7 23.6 0.26 11.3 0.0 21.3 28 0 0 28 28 25 3 Y_Y_Y domain Receptor_2B4 PF11465.8 VBB28561.1 - 1.1e-16 61.0 14.5 2.7 8.2 0.0 18.4 22 0 0 22 22 20 1 Natural killer cell receptor 2B4 fn3_2 PF16893.5 VBB28561.1 - 3.2e-15 56.1 0.0 1.1 9.4 0.0 13.0 13 0 0 13 13 12 2 Fibronectin type III domain Izumo-Ig PF16706.5 VBB28561.1 - 1.1e-11 44.7 8.3 0.12 12.4 0.0 11.7 13 0 0 13 13 12 1 Izumo-like Immunoglobulin domain DUF2369 PF10179.9 VBB28561.1 - 5.5e-10 39.5 0.4 5.7 7.4 0.0 13.3 20 0 0 20 20 15 1 Uncharacterised conserved protein (DUF2369) BiPBP_C PF06832.12 VBB28561.1 - 9e-09 35.3 0.0 1 9.5 0.0 9.8 11 1 0 11 11 8 1 Penicillin-Binding Protein C-terminus Family Ig_5 PF16681.5 VBB28561.1 - 1.5e-08 34.9 22.6 0.75 10.2 0.1 13.0 15 0 0 15 15 12 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ChitinaseA_N PF08329.10 VBB28561.1 - 4.6e-08 32.8 0.6 8.7 6.0 0.0 10.5 12 0 0 12 12 12 0 Chitinase A, N-terminal domain Ig_C17orf99 PF17736.1 VBB28561.1 - 8.9e-06 25.7 0.6 0.44 10.6 0.0 5.9 5 0 0 5 5 5 1 C17orf99 Ig domain bMG6 PF17962.1 VBB28561.1 - 0.0039 17.3 14.5 75 3.5 0.0 13.4 18 0 0 18 18 12 0 Bacterial macroglobulin domain 6 Kdo PF06293.14 VBB28561.1 - 0.019 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB28561.1 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-UBP_var PF17807.1 VBB28561.1 - 0.063 13.1 0.1 9.2 6.1 0.0 3.7 4 0 0 4 4 4 0 Variant UBP zinc finger DUF11 PF01345.18 VBB28561.1 - 0.21 11.9 21.3 21 5.5 0.1 11.5 13 0 0 13 13 11 0 Domain of unknown function DUF11 DUF4268 PF14088.6 VBB28561.1 - 2.9 7.8 5.8 79 3.1 0.0 6.0 8 0 0 8 8 6 0 Domain of unknown function (DUF4268) Cast PF10174.9 VBB28562.1 - 5.3e-20 71.3 17.7 2.3e-12 46.0 0.2 3.0 2 1 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.11 VBB28562.1 - 0.00049 19.1 7.6 0.00049 19.1 7.6 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein Atg14 PF10186.9 VBB28562.1 - 0.00097 18.3 11.4 0.03 13.4 3.1 2.2 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 INCA1 PF15142.6 VBB28562.1 - 0.029 14.4 0.4 0.079 13.0 0.4 1.7 1 0 0 1 1 1 0 INCA1 COG2 PF06148.11 VBB28562.1 - 0.32 11.1 2.9 5.8 7.0 0.1 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2730 PF10805.8 VBB28562.1 - 0.34 11.0 5.0 4.2 7.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) TMF_DNA_bd PF12329.8 VBB28562.1 - 0.91 9.6 10.6 3.3 7.8 0.0 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.13 VBB28562.1 - 1.7 8.8 8.0 24 5.1 0.3 4.0 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_3 PF13758.6 VBB28562.1 - 1.8 8.7 5.9 0.84 9.7 2.4 2.4 2 1 0 2 2 2 0 Prefoldin subunit FERM_M PF00373.18 VBB28562.1 - 1.8 9.0 6.8 1.5 9.2 3.3 2.3 1 1 1 2 2 2 0 FERM central domain DUF4407 PF14362.6 VBB28562.1 - 2.2 7.5 12.8 20 4.4 12.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 VBB28562.1 - 3.3 7.0 8.0 46 3.2 8.0 2.2 1 1 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 VBB28562.1 - 3.4 8.1 10.7 36 4.8 0.9 4.8 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 VBB28562.1 - 5.1 7.4 20.4 8.6 6.7 1.3 4.6 3 2 2 5 5 4 0 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 VBB28562.1 - 5.3 7.0 13.8 3.9 7.4 0.5 5.1 5 1 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CBP4 PF07960.11 VBB28562.1 - 5.4 6.9 7.3 0.45 10.4 0.6 2.6 1 1 2 3 3 3 0 CBP4 Stork_head PF10264.9 VBB28563.1 - 5.8e-15 55.2 0.1 1.9e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain DUF4817 PF16087.5 VBB28563.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Sec23_trunk PF04811.15 VBB28564.1 - 1.8e-75 253.7 0.0 2.7e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Pkinase PF00069.25 VBB28564.1 - 1.1e-65 221.7 0.0 1.7e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain IPK PF03770.16 VBB28564.1 - 9.2e-43 146.4 0.0 1.6e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pkinase_Tyr PF07714.17 VBB28564.1 - 2.5e-28 99.1 0.0 3.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sec23_helical PF04815.15 VBB28564.1 - 3e-22 78.4 0.1 5.8e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 VBB28564.1 - 1.3e-14 54.0 2.4 2.8e-14 52.9 2.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 VBB28564.1 - 1.5e-14 54.5 0.0 3.7e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 VBB28564.1 - 1.3e-05 25.0 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Kinase-like PF14531.6 VBB28564.1 - 2.2e-05 24.0 0.0 7.9e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 VBB28564.1 - 0.0033 16.8 0.1 0.0087 15.4 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FCH PF00611.23 VBB28565.1 - 6e-11 42.5 2.6 6.4e-11 42.4 1.2 1.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain AvrE_T3Es PF11725.8 VBB28565.1 - 0.00042 17.7 0.1 0.00047 17.5 0.1 1.0 1 0 0 1 1 1 1 AvrE-family Type-III effector proteins (T3Es) DUF499 PF04465.12 VBB28565.1 - 0.0047 14.7 0.9 0.0057 14.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF499) TadF PF16964.5 VBB28565.1 - 0.014 15.2 0.5 0.018 14.8 0.1 1.5 2 0 0 2 2 2 0 Putative tight adherence pilin protein F bZIP_1 PF00170.21 VBB28566.1 - 4e-08 33.2 12.8 4e-08 33.2 12.8 1.9 2 1 0 2 2 2 1 bZIP transcription factor DAG1 PF05454.11 VBB28566.1 - 0.007 15.8 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_PV PF03910.13 VBB28566.1 - 0.014 14.2 1.7 0.014 14.2 1.7 1.5 2 0 0 2 2 2 0 Adenovirus minor core protein PV bZIP_2 PF07716.15 VBB28566.1 - 0.029 14.4 6.8 0.079 13.0 6.8 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF5320 PF17253.2 VBB28566.1 - 3.6 8.7 6.1 7.5 7.7 3.1 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Adaptin_N PF01602.20 VBB28567.1 - 6.8e-156 519.9 15.6 1.1e-155 519.2 15.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 VBB28567.1 - 9.4e-67 224.1 11.3 1.4e-62 210.5 3.1 3.6 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 VBB28567.1 - 2.8e-30 104.7 0.8 6.9e-30 103.4 0.8 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 VBB28567.1 - 3.3e-21 75.5 2.0 1.5e-05 25.3 0.0 5.9 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 VBB28567.1 - 6.8e-10 38.3 8.1 0.019 15.2 0.0 6.8 8 0 0 8 8 6 3 HEAT repeat Alpha_adaptinC2 PF02883.20 VBB28567.1 - 7.7e-10 39.1 0.1 2e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 VBB28567.1 - 3.1e-07 29.9 6.9 5.8e-06 25.7 0.4 3.3 1 1 2 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 VBB28567.1 - 3.3e-05 23.6 1.6 0.022 14.3 0.2 3.3 2 2 0 2 2 2 2 CLASP N terminal Arm PF00514.23 VBB28567.1 - 4.1e-05 23.5 1.8 0.91 9.7 0.2 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 VBB28567.1 - 0.00047 20.6 0.5 7.8 7.1 0.1 4.9 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 VBB28567.1 - 0.0044 17.2 7.6 5 7.4 0.1 5.1 1 1 3 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 VBB28567.1 - 0.0046 16.9 2.7 0.0056 16.6 0.4 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Alpha_adaptin_C PF02296.16 VBB28567.1 - 0.16 12.1 1.6 0.32 11.2 0.3 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain RasGEF_N_2 PF14663.6 VBB28567.1 - 2.1 8.8 6.2 6.9 7.1 0.1 4.2 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PID_2 PF14719.6 VBB28568.1 - 0.0021 18.0 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) DUF2040 PF09745.9 VBB28568.1 - 4.1 7.5 8.2 16 5.6 0.2 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 55 (DUF2040) Galactosyl_T PF01762.21 VBB28569.1 - 1.1e-38 133.0 3.2 1.5e-38 132.6 3.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase Pentaxin PF00354.17 VBB28570.1 - 0.39 10.4 2.0 3 7.5 0.0 2.2 1 1 0 2 2 2 0 Pentaxin family Fer2 PF00111.27 VBB28571.1 - 2.4e-12 46.7 0.4 3.2e-12 46.2 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ATP-synt_S1 PF05827.12 VBB28572.1 - 8.9e-23 80.7 0.2 1.9e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) TSP_1 PF00090.19 VBB28573.1 - 2.8e-71 235.6 248.2 2.1e-08 34.2 7.9 20.3 19 0 0 19 19 19 18 Thrombospondin type 1 domain GON PF08685.11 VBB28573.1 - 7.2e-69 231.7 0.6 7.2e-69 231.7 0.6 2.4 2 0 0 2 2 2 1 GON domain ADAM_spacer1 PF05986.14 VBB28573.1 - 8.3e-32 109.6 0.1 1.2e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 VBB28573.1 - 2.7e-20 72.6 9.6 2.7e-20 72.6 9.6 11.9 7 4 5 12 12 12 2 ADAM cysteine-rich domain Homeodomain PF00046.29 VBB28575.1 - 3.8e-22 77.9 11.0 4.8e-22 77.6 11.0 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB28575.1 - 0.0084 16.0 0.5 0.015 15.2 0.5 1.4 1 0 0 1 1 1 1 Homeobox KN domain Fibin PF15819.5 VBB28575.1 - 0.037 13.8 1.2 0.043 13.6 1.2 1.2 1 0 0 1 1 1 0 Fin bud initiation factor homologue HTH_23 PF13384.6 VBB28575.1 - 0.041 13.7 0.2 0.041 13.7 0.2 1.5 2 0 0 2 2 2 0 Homeodomain-like domain Homez PF11569.8 VBB28575.1 - 0.1 12.1 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Rtf2 PF04641.12 VBB28576.1 - 0.6 9.4 12.2 1 8.7 12.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_Rpc4 PF05132.14 VBB28576.1 - 7.9 6.9 9.8 3.7 8.0 7.2 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 FRG2 PF15315.6 VBB28576.1 - 8.1 6.6 12.4 11 6.2 12.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 COX6B PF02297.17 VBB28578.1 - 7.3e-11 42.1 2.7 7.3e-11 42.1 2.7 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Utp11 PF03998.13 VBB28579.1 - 6.5e-63 212.9 24.1 7.4e-63 212.8 24.1 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 VBB28579.1 - 0.16 11.3 3.7 0.21 10.9 0.2 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 ECR1_N PF14382.6 VBB28580.1 - 6.7e-11 41.8 0.1 3.3e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region DUF1667 PF07892.11 VBB28580.1 - 0.0038 17.2 0.3 0.007 16.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1667) zf-CCCH PF00642.24 VBB28581.1 - 1.2 9.2 23.1 1.7 8.7 1.9 4.0 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 VBB28581.1 - 2.6 8.8 15.2 5.5 7.7 0.4 3.6 1 1 2 3 3 3 0 Torus domain zf-C3H1 PF10650.9 VBB28581.1 - 3.1 7.6 9.9 1.3 8.8 0.5 3.7 4 0 0 4 4 4 0 Putative zinc-finger domain TSP_1 PF00090.19 VBB28582.1 - 5.4e-61 202.6 163.6 8.5e-11 41.9 9.0 10.7 10 1 0 10 10 10 9 Thrombospondin type 1 domain EELM2 PF15863.5 VBB28582.1 - 2.9 8.0 6.7 4.8 7.3 0.1 3.3 3 0 0 3 3 3 0 Extended EGL-27 and MTA1 homology domain Translin PF01997.16 VBB28584.1 - 9.8e-44 149.8 0.1 1.2e-43 149.5 0.1 1.1 1 0 0 1 1 1 1 Translin family FA_hydroxylase PF04116.13 VBB28586.1 - 1.7e-15 57.5 5.3 1.7e-15 57.5 5.3 2.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MCM PF00493.23 VBB28587.1 - 3.9e-99 330.3 0.1 5.7e-99 329.8 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 VBB28587.1 - 7.3e-40 135.7 1.6 1.5e-39 134.7 1.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 VBB28587.1 - 4.5e-27 94.3 1.6 1.3e-26 92.8 1.6 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 VBB28587.1 - 4.6e-14 52.9 0.0 1.1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 VBB28587.1 - 1.4e-06 27.8 0.0 0.00061 19.2 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB28587.1 - 5.6e-06 26.4 0.0 1.7e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 VBB28587.1 - 0.0095 15.8 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 VBB28587.1 - 0.015 15.0 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain HypA PF01155.19 VBB28587.1 - 0.029 14.4 0.4 0.086 12.9 0.4 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3071 PF11268.8 VBB28587.1 - 0.26 11.3 2.5 2.8 8.0 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3071) zf-U11-48K PF05253.12 VBB28587.1 - 0.35 10.8 2.6 3.2 7.8 0.4 3.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger RNA_pol PF00940.19 VBB28588.1 - 6e-143 476.6 0.0 9.9e-143 475.9 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 VBB28588.1 - 1.2e-13 51.2 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal MOZ_SAS PF01853.18 VBB28589.1 - 3.6e-81 271.1 0.2 3.6e-81 271.1 0.2 1.9 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 VBB28589.1 - 3.1e-22 77.9 3.7 3.1e-22 77.9 3.7 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 VBB28589.1 - 1.6e-17 63.1 0.0 4.7e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 VBB28589.1 - 0.00016 22.0 0.0 0.00065 20.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB28589.1 - 0.00055 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GLYCAM-1 PF05242.11 VBB28589.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) HLH PF00010.26 VBB28591.1 - 1.4e-11 44.1 0.4 2.3e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aminotran_1_2 PF00155.21 VBB28592.1 - 6.1e-66 223.0 0.0 7.1e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 VBB28592.1 - 9.7e-06 25.1 0.0 2.1e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 VBB28592.1 - 8.4e-05 21.3 0.0 0.00014 20.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 VBB28592.1 - 0.00011 21.4 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V COE1_DBD PF16422.5 VBB28593.1 - 1e-126 421.1 0.4 1.4e-126 420.6 0.4 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 VBB28593.1 - 3e-27 94.1 0.5 6.1e-27 93.1 0.5 1.6 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 VBB28593.1 - 1.2e-10 41.3 0.5 2.6e-10 40.2 0.5 1.6 1 0 0 1 1 1 1 IPT/TIG domain RHD_dimer PF16179.5 VBB28593.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Rel homology dimerisation domain Pkinase PF00069.25 VBB28595.1 - 4.1e-45 154.2 0.0 6.3e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28595.1 - 2.5e-22 79.4 0.0 3.6e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB28595.1 - 2.1e-07 30.5 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB28595.1 - 5.7e-05 22.1 0.0 9.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB28595.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BRCT PF00533.26 VBB28596.1 - 2.7e-28 98.2 0.2 2.5e-07 31.0 0.0 4.7 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 VBB28596.1 - 3.9e-24 84.4 1.5 8.9e-13 48.0 0.2 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT_2 PF16589.5 VBB28596.1 - 6.5e-16 58.5 0.0 3.7e-05 24.0 0.0 4.6 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 VBB28596.1 - 2.7e-09 36.8 0.0 6e-07 29.3 0.0 3.4 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 VBB28596.1 - 0.00049 20.3 0.0 0.52 10.6 0.0 3.5 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain rve PF00665.26 VBB28599.1 - 0.047 13.9 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain BDM PF10684.9 VBB28600.1 - 0.085 13.2 0.2 0.36 11.2 0.2 2.1 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Bestrophin PF01062.21 VBB28601.1 - 5.8e-23 81.7 0.1 6.4e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Peptidase_A2B PF12384.8 VBB28601.1 - 0.0062 16.1 0.0 0.0068 16.0 0.0 1.1 1 0 0 1 1 1 1 Ty3 transposon peptidase Bestrophin PF01062.21 VBB28602.1 - 1.2e-34 120.0 0.8 1.7e-34 119.6 0.8 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel NUDIX PF00293.28 VBB28603.1 - 2.5e-15 56.7 0.0 8.8e-15 54.9 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain PAS_7 PF12860.7 VBB28603.1 - 0.032 14.4 0.0 0.12 12.5 0.0 2.0 2 1 1 3 3 3 0 PAS fold TUDOR PF00567.24 VBB28604.1 - 2.7e-15 56.5 0.6 5.2e-05 23.3 0.0 3.9 3 0 0 3 3 3 3 Tudor domain Mre11_DNA_bind PF04152.14 VBB28604.1 - 0.021 15.2 1.6 0.36 11.1 0.8 2.5 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain VWA_2 PF13519.6 VBB28605.1 - 0.00027 21.6 0.1 0.0029 18.2 0.0 2.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 VBB28605.1 - 0.027 13.9 1.3 0.19 11.1 0.2 2.6 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein Kin17_mid PF10357.9 VBB28607.1 - 8.7e-46 154.9 4.7 8.7e-46 154.9 4.7 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 VBB28607.1 - 4.6e-17 61.9 0.7 4.6e-15 55.5 0.1 2.5 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 VBB28607.1 - 0.0089 16.4 6.5 0.0089 16.4 6.5 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Imm6 PF14434.6 VBB28607.1 - 0.03 14.3 1.2 0.083 12.8 0.4 2.1 2 0 0 2 2 2 0 Immunity protein Imm6 BTD PF09270.10 VBB28607.1 - 0.1 12.8 1.9 4.6 7.5 0.1 2.5 2 1 0 2 2 2 0 Beta-trefoil DNA-binding domain zf-C2H2_2 PF12756.7 VBB28607.1 - 5 7.5 11.7 1.7 9.0 5.0 2.7 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Rotamase_3 PF13616.6 VBB28608.1 - 1.3e-19 70.8 0.4 6.3e-19 68.6 0.4 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 VBB28608.1 - 2.1e-16 60.6 0.0 4.7e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 VBB28608.1 - 0.00013 22.8 0.0 0.00021 22.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain IQ PF00612.27 VBB28609.1 - 1.8e-15 55.2 17.7 5.5e-07 28.8 1.3 3.7 2 1 1 3 3 3 3 IQ calmodulin-binding motif UPF0146 PF03686.13 VBB28609.1 - 0.066 13.1 0.1 0.076 12.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Herpes_U59 PF04529.12 VBB28609.1 - 0.07 12.2 0.4 0.068 12.2 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus U59 protein Lung_7-TM_R PF06814.13 VBB28610.1 - 1.1e-43 149.5 6.0 7.1e-32 110.8 1.9 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor LIM PF00412.22 VBB28611.1 - 4.8e-55 183.6 69.9 2.9e-15 56.2 5.6 5.2 5 0 0 5 5 5 5 LIM domain Flavodoxin_4 PF12682.7 VBB28611.1 - 0.0075 16.0 0.2 0.057 13.1 0.1 2.1 2 0 0 2 2 2 1 Flavodoxin CENP-T_C PF15511.6 VBB28612.1 - 7e-08 32.5 0.0 8.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 VBB28612.1 - 2e-05 24.7 0.1 0.00027 21.2 0.1 2.3 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 VBB28612.1 - 3.3e-05 24.2 0.0 5.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 VBB28612.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 VBB28612.1 - 0.00048 20.5 0.2 0.00072 19.9 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 VBB28612.1 - 0.0027 17.7 0.1 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 VBB28612.1 - 0.0054 16.8 0.0 0.0066 16.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAFII28 PF04719.14 VBB28612.1 - 0.061 13.4 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 hTAFII28-like protein conserved region STELLO PF03385.17 VBB28612.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 STELLO glycosyltransferases Histone PF00125.24 VBB28613.1 - 5.2e-24 85.1 0.7 7.4e-24 84.6 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB28613.1 - 3.9e-07 30.2 0.1 7.8e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 VBB28613.1 - 0.00027 21.4 0.0 0.0008 19.9 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 VBB28613.1 - 0.00087 19.4 0.1 0.0011 19.1 0.1 1.2 1 0 0 1 1 1 1 YscO-like protein DUF1931 PF09123.11 VBB28613.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) Histone_H2A_C PF16211.5 VBB28614.1 - 3.2e-20 71.6 0.9 5.8e-20 70.7 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 VBB28614.1 - 4.1e-16 59.5 0.0 5.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB28614.1 - 1.7e-05 25.0 0.0 3.9e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.19 VBB28616.1 - 6.4e-28 96.9 0.3 1.6e-27 95.7 0.3 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family ETF_alpha PF00766.19 VBB28616.1 - 0.069 13.2 0.9 0.087 12.9 0.1 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain YihI PF04220.12 VBB28616.1 - 1.7 8.4 11.3 0.18 11.5 5.2 1.9 2 0 0 2 2 2 0 Der GTPase activator (YihI) SNF2_N PF00176.23 VBB28617.1 - 8.5e-73 245.1 0.6 1.6e-72 244.2 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 VBB28617.1 - 1.6e-42 144.1 3.5 1.6e-42 144.1 3.5 3.9 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 VBB28617.1 - 2e-30 105.8 4.6 2e-30 105.8 4.6 4.0 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 VBB28617.1 - 3.5e-21 75.6 0.1 5.4e-20 71.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB28617.1 - 2.8e-11 43.7 0.0 2.8e-11 43.7 0.0 2.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB28617.1 - 5.5e-07 29.5 0.1 2.1e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 VBB28617.1 - 2.7e-05 23.5 0.5 7.7e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 VBB28617.1 - 0.00036 20.4 0.6 0.0018 18.1 0.3 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.31 VBB28617.1 - 0.0012 19.0 6.0 0.034 14.3 0.1 3.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Dus PF01207.17 VBB28618.1 - 1.8e-64 217.8 0.0 2.3e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NanE PF04131.14 VBB28618.1 - 1.1e-05 24.7 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 VBB28618.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.17 VBB28618.1 - 0.04 13.2 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase SOR_SNZ PF01680.17 VBB28618.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 SOR/SNZ family Zip PF02535.22 VBB28619.1 - 0.053 12.7 1.5 0.057 12.6 1.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 VBB28619.1 - 0.074 11.0 1.7 0.077 10.9 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family S-antigen PF05756.11 VBB28619.1 - 0.12 12.8 4.1 0.14 12.6 4.1 1.2 1 0 0 1 1 1 0 S-antigen protein DUF4746 PF15928.5 VBB28619.1 - 0.17 11.3 8.9 0.16 11.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 VBB28619.1 - 0.19 11.9 20.1 0.22 11.7 20.1 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 VBB28619.1 - 0.62 9.8 9.5 0.65 9.8 9.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Connexin PF00029.19 VBB28619.1 - 1.5 8.5 5.1 1.5 8.5 5.1 1.1 1 0 0 1 1 1 0 Connexin MAS20 PF02064.15 VBB28619.1 - 1.7 8.7 7.4 2.2 8.4 7.4 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Eapp_C PF10238.9 VBB28619.1 - 1.7 8.7 6.3 2.1 8.4 6.3 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Paf1 PF03985.13 VBB28619.1 - 2 7.4 17.6 2.1 7.2 17.6 1.0 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 VBB28619.1 - 2.2 8.2 11.5 2.4 8.1 11.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 VBB28619.1 - 2.6 7.7 11.8 3.4 7.3 11.8 1.2 1 0 0 1 1 1 0 FAM176 family DUF4820 PF16091.5 VBB28619.1 - 3 7.1 6.8 2.9 7.2 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PBP_sp32 PF07222.12 VBB28619.1 - 3.1 7.2 15.6 3.6 7.0 15.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CobT PF06213.12 VBB28619.1 - 3.6 6.9 16.4 3.9 6.8 16.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 VBB28619.1 - 3.8 6.8 13.6 4 6.7 13.6 1.1 1 0 0 1 1 1 0 NOA36 protein NARP1 PF12569.8 VBB28619.1 - 3.9 6.3 9.1 3.9 6.3 9.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TRAP_alpha PF03896.16 VBB28619.1 - 3.9 6.6 8.8 4.1 6.5 8.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 VBB28619.1 - 4.2 5.6 12.1 4.3 5.5 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3464 PF11947.8 VBB28619.1 - 5.6 6.7 5.2 5.6 6.7 5.2 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RAB3GAP2_C PF14656.6 VBB28619.1 - 6 5.0 5.3 6.1 5.0 5.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Presenilin PF01080.17 VBB28619.1 - 6.3 5.4 6.8 6.8 5.3 6.8 1.0 1 0 0 1 1 1 0 Presenilin TFB6 PF17110.5 VBB28619.1 - 6.5 6.5 8.2 6.3 6.5 8.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NPR3 PF03666.13 VBB28619.1 - 7.7 5.2 6.9 8.5 5.0 6.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-BED PF02892.15 VBB28620.1 - 2e-10 40.5 2.1 2e-10 40.5 2.1 2.8 3 0 0 3 3 3 1 BED zinc finger ZirS_C PF16583.5 VBB28620.1 - 0.14 11.7 1.7 2.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Carn_acyltransf PF00755.20 VBB28622.1 - 6.6e-160 533.6 0.0 7.5e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase HNOB PF07700.15 VBB28622.1 - 0.076 13.0 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Haem-NO-binding MFS_1 PF07690.16 VBB28623.1 - 1.3e-32 113.1 35.5 9.7e-31 107.0 33.2 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily RA PF00788.23 VBB28624.1 - 2.3e-18 66.6 0.2 6.1e-18 65.2 0.2 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 VBB28624.1 - 9.4e-15 54.2 1.0 9.4e-15 54.2 1.0 1.9 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.22 VBB28624.1 - 5.8e-12 45.3 8.3 1e-11 44.5 8.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras_bdg_2 PF14847.6 VBB28624.1 - 0.044 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PHD PF00628.29 VBB28624.1 - 3.8 7.5 10.4 8.9 6.3 10.4 1.7 1 0 0 1 1 1 0 PHD-finger Methyltransf_32 PF13679.6 VBB28626.1 - 3.5e-17 62.8 3.6 9.2e-17 61.5 3.6 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB28626.1 - 0.00017 22.2 0.1 0.00031 21.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB28626.1 - 0.00044 20.1 0.3 0.0009 19.1 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB28626.1 - 0.0036 17.9 0.0 0.0067 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 VBB28626.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PCMT PF01135.19 VBB28626.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 VBB28626.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TMEM135_C_rich PF15982.5 VBB28627.1 - 5.4e-25 88.5 1.9 1.3e-24 87.3 1.9 1.7 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 SUV3_C PF12513.8 VBB28627.1 - 0.059 13.3 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal POTRA_2 PF08479.11 VBB28627.1 - 0.13 12.1 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 POTRA domain, ShlB-type Streptin-Immun PF11083.8 VBB28630.1 - 0.3 11.5 4.8 5.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein DUF948 PF06103.11 VBB28630.1 - 0.55 10.5 0.1 0.55 10.5 0.1 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Glutaredoxin PF00462.24 VBB28631.1 - 4.3e-35 119.7 0.0 1.5e-16 60.3 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 VBB28631.1 - 3.2e-12 46.4 0.2 1.2e-11 44.5 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin F-box-like PF12937.7 VBB28631.1 - 6.7e-06 25.9 0.1 6.7e-06 25.9 0.1 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 VBB28631.1 - 7.9e-06 25.6 1.4 3.1e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 F-box domain DIM1 PF02966.16 VBB28631.1 - 0.0027 17.5 0.1 0.0068 16.2 0.1 1.7 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 VBB28631.1 - 0.0043 17.5 0.1 1.1 9.7 0.0 3.4 2 1 0 2 2 2 1 Thioredoxin-like domain GST_N_3 PF13417.6 VBB28631.1 - 0.051 14.0 0.0 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Val_tRNA-synt_C PF10458.9 VBB28631.1 - 0.055 13.8 0.0 3.3 8.1 0.1 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Svf1_C PF17187.4 VBB28632.1 - 0.23 11.3 2.5 0.47 10.3 0.5 2.3 1 1 1 2 2 2 0 Svf1-like C-terminal lipocalin-like domain Motile_Sperm PF00635.26 VBB28633.1 - 1.9e-18 66.3 1.9 1.9e-18 66.3 1.9 2.5 2 1 0 2 2 2 1 MSP (Major sperm protein) domain Lipocalin_2 PF08212.12 VBB28634.1 - 0.0024 17.8 0.3 0.0033 17.3 0.3 1.2 1 0 0 1 1 1 1 Lipocalin-like domain VIT PF08487.10 VBB28634.1 - 0.016 15.5 0.3 0.027 14.7 0.3 1.3 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Ets PF00178.22 VBB28635.1 - 4e-31 107.3 3.0 9.1e-31 106.2 3.0 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 VBB28635.1 - 1.1e-14 54.2 0.1 2.3e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain TGT_C2 PF14810.6 VBB28635.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase DUF1098 PF06497.11 VBB28636.1 - 0.00073 20.0 0.4 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1098) Mog1 PF04603.12 VBB28636.1 - 0.3 11.4 2.1 0.54 10.6 0.2 2.0 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Innexin PF00876.18 VBB28637.1 - 9e-106 354.1 14.6 1.1e-105 353.8 14.6 1.0 1 0 0 1 1 1 1 Innexin Catalase-rel PF06628.12 VBB28637.1 - 0.086 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive VanZ PF04892.12 VBB28637.1 - 0.93 10.2 8.0 0.31 11.7 4.6 2.0 3 0 0 3 3 3 0 VanZ like family CAP_N PF01213.19 VBB28639.1 - 2.7e-85 286.7 1.2 2.7e-85 286.7 1.2 3.1 3 0 0 3 3 3 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 VBB28639.1 - 1.7e-52 177.2 3.2 6.6e-52 175.3 3.2 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal WH2 PF02205.20 VBB28639.1 - 0.0089 15.8 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 1 WH2 motif TBCC PF07986.12 VBB28639.1 - 0.037 13.8 1.8 0.11 12.2 0.8 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Thioredoxin_4 PF13462.6 VBB28639.1 - 0.065 13.4 0.4 0.19 11.9 0.4 1.8 1 0 0 1 1 1 0 Thioredoxin Sulfatase PF00884.23 VBB28640.1 - 3.8e-57 194.0 1.1 5.6e-57 193.5 1.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.8 VBB28640.1 - 1.3e-08 35.4 0.7 1.3e-08 35.4 0.7 2.3 2 0 0 2 2 2 1 Sulfatase protein Phosphodiest PF01663.22 VBB28640.1 - 1.6e-06 28.0 0.1 4.2e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 VBB28640.1 - 0.027 14.7 0.2 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) zf-C2HC_2 PF13913.6 VBB28641.1 - 2.9e-07 30.2 0.6 4.9e-07 29.5 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF4061 PF13270.6 VBB28641.1 - 0.027 14.8 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) zf-CHCC PF10276.9 VBB28641.1 - 0.027 14.5 0.4 0.049 13.7 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger domain zf-C2H2 PF00096.26 VBB28641.1 - 0.088 13.3 0.8 0.48 11.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type ATP-gua_PtransN PF02807.15 VBB28641.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain VATC PF18716.1 VBB28641.1 - 0.12 12.2 1.0 0.21 11.5 1.0 1.4 1 0 0 1 1 1 0 Vms1-associating treble clef domain DUF4101 PF13355.6 VBB28641.1 - 0.81 10.1 3.5 6.8 7.2 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) PGK PF00162.19 VBB28642.1 - 6.2e-51 173.5 0.9 6.9e-51 173.4 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Cupin_3 PF05899.12 VBB28642.1 - 0.086 12.5 2.3 0.12 12.1 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Homeodomain PF00046.29 VBB28643.1 - 4.7e-21 74.4 5.7 6.9e-21 73.8 4.4 2.0 2 0 0 2 2 2 1 Homeodomain Spore_coat_CotO PF14153.6 VBB28643.1 - 0.01 15.7 11.6 0.01 15.7 11.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Homeobox_KN PF05920.11 VBB28643.1 - 0.011 15.7 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain TERB2 PF15101.6 VBB28643.1 - 0.012 15.7 5.9 0.012 15.7 5.9 2.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CDC45 PF02724.14 VBB28643.1 - 0.013 13.8 6.0 0.026 12.8 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.13 VBB28643.1 - 0.021 15.5 19.2 0.021 15.5 19.2 4.1 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 VBB28643.1 - 0.022 14.7 20.5 0.053 13.5 11.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PTPRCAP PF15713.5 VBB28643.1 - 0.079 13.2 15.4 0.04 14.2 11.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Neur_chan_memb PF02932.16 VBB28643.1 - 0.29 11.1 12.5 0.41 10.7 6.4 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 VBB28643.1 - 0.68 10.2 20.0 2.2 8.5 3.4 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AUX_IAA PF02309.16 VBB28643.1 - 1.6 8.5 14.2 0.55 10.0 9.5 2.1 2 0 0 2 2 2 0 AUX/IAA family DUF4770 PF15994.5 VBB28643.1 - 1.9 8.7 11.8 0.078 13.2 3.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF572 PF04502.13 VBB28643.1 - 2.8 7.5 19.0 0.87 9.1 9.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 VBB28643.1 - 4.7 7.0 20.8 2.8 7.7 16.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM83 PF07894.12 VBB28643.1 - 5.2 6.5 11.4 0.99 8.9 4.5 2.3 2 0 0 2 2 2 0 FAM83 A-H RIFIN PF02009.16 VBB28643.1 - 5.7 6.7 15.7 2.1 8.2 1.4 2.4 2 0 0 2 2 2 0 Rifin DUF4638 PF15472.6 VBB28643.1 - 8.9 6.0 12.6 25 4.5 12.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) 7tm_1 PF00001.21 VBB28644.1 - 1.4e-10 41.0 25.5 2.5e-10 40.1 25.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB28644.1 - 0.0023 17.6 31.1 0.0036 17.0 31.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LCD1 PF09798.9 VBB28644.1 - 0.036 12.6 5.3 0.073 11.6 0.5 2.3 2 1 0 2 2 2 0 DNA damage checkpoint protein DUF5316 PF17247.2 VBB28644.1 - 0.29 11.2 6.2 13 5.9 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Acyltransferase PF01553.21 VBB28645.1 - 6.2e-10 38.8 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 VBB28645.1 - 8.9e-10 38.5 0.2 2.4e-09 37.2 0.2 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus PTN_MK_C PF01091.18 VBB28646.1 - 0.11 12.9 2.2 0.72 10.3 0.3 2.9 3 0 0 3 3 3 0 PTN/MK heparin-binding protein family, C-terminal domain Glyco_transf_92 PF01697.27 VBB28647.1 - 2.3e-31 109.4 0.1 3.8e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 VBB28647.1 - 0.007 16.8 0.0 0.016 15.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Anti-TRAP PF15777.5 VBB28647.1 - 0.13 12.3 0.7 0.58 10.2 0.0 2.2 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_S8 PF00410.19 VBB28648.1 - 0.047 13.6 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S8 DER1 PF04511.15 VBB28649.1 - 3.6e-68 229.3 12.3 4.2e-68 229.0 12.3 1.0 1 0 0 1 1 1 1 Der1-like family ubiquitin PF00240.23 VBB28650.1 - 7.3e-08 32.0 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 VBB28650.1 - 0.00021 21.8 0.2 0.00057 20.4 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 VBB28650.1 - 0.00023 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4381 PF14316.6 VBB28650.1 - 0.074 13.3 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Thioredoxin PF00085.20 VBB28651.1 - 2.2e-26 91.8 0.0 1.9e-24 85.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 VBB28651.1 - 1.2e-14 54.6 0.0 2e-09 37.6 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 VBB28651.1 - 2e-05 25.0 0.4 0.0015 19.0 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 VBB28651.1 - 0.0018 18.4 0.1 0.0039 17.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 VBB28651.1 - 0.015 15.7 0.2 1.8 8.9 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin-like HyaE PF07449.11 VBB28651.1 - 0.046 13.7 0.0 4.1 7.4 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Ribosomal_S8 PF00410.19 VBB28652.1 - 2.1e-22 79.4 0.0 2.7e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 S1 PF00575.23 VBB28653.1 - 2.4e-14 53.4 0.0 5.7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 VBB28653.1 - 5.4e-12 45.9 0.0 1.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Peptidase_S24 PF00717.23 VBB28653.1 - 4.7e-09 36.1 0.1 4.7e-09 36.1 0.1 2.1 3 0 0 3 3 3 1 Peptidase S24-like RNA_pol_Rbc25 PF08292.12 VBB28653.1 - 0.05 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 SIX1_SD PF16878.5 VBB28655.1 - 7.7e-38 129.4 1.0 7.7e-38 129.4 1.0 1.9 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 VBB28655.1 - 9.7e-15 54.2 1.4 9.7e-15 54.2 1.4 2.4 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 VBB28655.1 - 5.9e-13 48.5 1.0 1.7e-12 47.0 1.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 VBB28655.1 - 0.039 13.4 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 VBB28655.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Ank_4 PF13637.6 VBB28656.1 - 4.5e-21 74.9 1.0 1.3e-12 48.0 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB28656.1 - 6.3e-17 61.9 0.9 2.7e-16 59.9 0.4 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 VBB28656.1 - 2.9e-15 55.9 1.2 7.1e-07 29.4 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 VBB28656.1 - 7.2e-14 50.6 0.5 1.2e-05 25.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 VBB28656.1 - 1.9e-13 50.4 1.0 6.6e-07 29.5 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_9 PF14604.6 VBB28656.1 - 3.6e-09 36.4 0.0 9.7e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB28656.1 - 2.4e-08 33.4 0.1 7.7e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB28656.1 - 0.0018 17.9 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CLZ PF16526.5 VBB28656.1 - 2.7 8.4 7.2 20 5.7 0.2 3.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HLH PF00010.26 VBB28657.1 - 7e-14 51.5 0.8 1e-13 51.0 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Innexin PF00876.18 VBB28658.1 - 2.5e-95 319.8 8.6 5.5e-80 269.3 5.2 2.1 1 1 1 2 2 2 2 Innexin Ribosomal_L37 PF08561.10 VBB28658.1 - 0.19 12.2 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 TPR_19 PF14559.6 VBB28659.1 - 0.00067 20.1 0.1 0.0041 17.6 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat API5 PF05918.11 VBB28660.1 - 5.2e-69 233.4 12.4 8.3e-69 232.8 12.4 1.3 1 1 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 VBB28660.1 - 0.012 16.0 0.2 0.089 13.2 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats FYVE PF01363.21 VBB28661.1 - 7.9e-15 54.8 9.2 2.1e-14 53.4 9.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 VBB28661.1 - 0.0029 17.6 0.5 1.2 9.1 0.0 3.0 3 0 0 3 3 3 2 RUN domain IBR PF01485.21 VBB28661.1 - 0.023 14.9 4.7 0.063 13.5 4.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SAP PF02037.27 VBB28661.1 - 0.025 14.3 4.2 1.5 8.7 0.1 2.9 2 0 0 2 2 2 0 SAP domain zf_C2HC_14 PF18574.1 VBB28661.1 - 0.85 9.5 6.2 2 8.2 6.2 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain HypA PF01155.19 VBB28661.1 - 1.1 9.4 3.8 0.67 10.0 1.3 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NPV_P10 PF05531.12 VBB28661.1 - 2 8.9 10.6 0.034 14.6 1.1 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Bcr-Abl_Oligo PF09036.10 VBB28661.1 - 2.5 8.2 4.5 23 5.1 0.2 3.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain RabGAP-TBC PF00566.18 VBB28662.1 - 7.5e-50 169.6 2.0 9.1e-50 169.3 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1118 PF06549.12 VBB28662.1 - 0.02 15.2 0.4 0.048 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) ECSIT_C PF14784.6 VBB28662.1 - 0.072 13.4 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DNA_ligase_aden PF01653.18 VBB28662.1 - 0.089 11.9 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain WD40 PF00400.32 VBB28662.1 - 0.22 12.4 2.3 0.53 11.2 0.1 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_M24 PF00557.24 VBB28664.1 - 2.4e-40 138.5 0.0 3.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 VBB28664.1 - 8.8e-39 133.2 0.0 1.7e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 VBB28664.1 - 2.1e-22 78.9 0.1 6.4e-22 77.4 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 VBB28664.1 - 2.2e-13 51.0 0.0 2.2e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Type2_restr_D3 PF16902.5 VBB28664.1 - 0.019 14.9 0.2 0.053 13.4 0.2 1.7 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Ets PF00178.22 VBB28665.1 - 7.5e-33 112.9 1.0 1.2e-32 112.2 1.0 1.3 1 0 0 1 1 1 1 Ets-domain KTSC PF13619.6 VBB28665.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 KTSC domain DUF4652 PF15525.6 VBB28665.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) PQQ_2 PF13360.6 VBB28666.1 - 3.5e-17 62.8 0.0 1.2e-13 51.2 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 VBB28666.1 - 3.4e-15 56.0 0.0 0.0077 16.7 0.0 6.1 6 0 0 6 6 6 3 PQQ-like domain PQQ PF01011.21 VBB28666.1 - 3.9e-15 54.9 0.0 2.9e-08 33.2 0.0 5.9 6 0 0 6 6 6 2 PQQ enzyme repeat AMP-binding PF00501.28 VBB28666.1 - 4.5e-15 55.2 0.1 1.8e-14 53.2 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme dCMP_cyt_deam_1 PF00383.23 VBB28666.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 VBB28666.1 - 7e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase DUF5050 PF16472.5 VBB28666.1 - 0.0015 17.8 0.0 0.0051 16.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5050) PP-binding PF00550.25 VBB28666.1 - 0.18 12.2 1.3 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphopantetheine attachment site CEBP_ZZ PF16366.5 VBB28666.1 - 6.2 7.1 5.6 0.71 10.2 0.3 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain ORC4_C PF14629.6 VBB28667.1 - 2.2e-07 30.5 1.7 3.3e-07 29.9 1.7 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 VBB28667.1 - 0.00044 20.7 0.1 0.0028 18.0 0.0 2.3 2 2 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 VBB28667.1 - 0.005 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NHL PF01436.21 VBB28668.1 - 2.2e-21 74.7 9.0 5.3e-08 32.5 0.1 4.5 4 1 1 5 5 5 3 NHL repeat DUF5128 PF17170.4 VBB28668.1 - 0.00018 20.8 0.2 0.035 13.3 0.0 3.1 3 0 0 3 3 3 2 6-bladed beta-propeller Astacin PF01400.24 VBB28669.1 - 1.5e-70 236.7 0.0 2e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 VBB28669.1 - 5.1e-05 23.7 7.9 9.3e-05 22.9 7.9 1.5 1 0 0 1 1 1 1 ShK domain-like HECT PF00632.25 VBB28670.1 - 3.3e-79 266.6 0.1 5e-79 266.0 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 VBB28670.1 - 4.4e-12 46.0 2.8 4.4e-12 46.0 2.8 2.3 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2 PF00096.26 VBB28671.1 - 0.13 12.8 6.8 0.9 10.1 2.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type ASC PF00858.24 VBB28672.1 - 3.7e-20 72.3 16.2 4.3e-20 72.1 14.9 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Vps54 PF07928.12 VBB28673.1 - 2.3e-41 141.4 0.2 2.3e-41 141.4 0.2 3.1 4 0 0 4 4 4 1 Vps54-like protein Vps54_N PF10475.9 VBB28673.1 - 3.8e-12 46.1 7.2 3.8e-12 46.1 7.2 2.6 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Tweety PF04906.13 VBB28673.1 - 0.058 12.0 6.0 0.035 12.8 0.4 2.7 3 0 0 3 3 3 0 Tweety Sec8_exocyst PF04048.14 VBB28673.1 - 0.14 12.1 4.3 0.055 13.4 0.7 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain CENP-W PF15510.6 VBB28674.1 - 0.047 13.9 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 CENP-W protein RtcB PF01139.17 VBB28676.1 - 1.5e-82 278.0 0.1 1.7e-82 277.9 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB NHL PF01436.21 VBB28677.1 - 2.5e-55 181.8 28.1 4.9e-10 38.9 0.1 7.5 7 0 0 7 7 7 6 NHL repeat DUF5128 PF17170.4 VBB28677.1 - 2.1e-16 60.0 0.2 2.2e-06 27.1 0.0 3.3 1 1 2 3 3 3 3 6-bladed beta-propeller SGL PF08450.12 VBB28677.1 - 3e-10 40.1 0.1 0.018 14.7 0.0 4.9 2 1 3 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region Filamin PF00630.19 VBB28677.1 - 1.8e-07 31.9 0.0 4.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.24 VBB28677.1 - 1.7e-05 24.9 16.8 0.00063 19.9 8.8 4.1 4 1 0 4 4 3 2 B-box zinc finger zf-RING_2 PF13639.6 VBB28677.1 - 0.0019 18.5 11.3 0.0019 18.5 11.3 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 VBB28677.1 - 0.0029 17.5 11.3 0.0029 17.5 11.3 3.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB28677.1 - 0.0043 16.9 12.2 0.0043 16.9 12.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4934 PF16288.5 VBB28677.1 - 0.026 14.5 0.0 0.13 12.2 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4934) TAF1_subA PF14929.6 VBB28677.1 - 0.042 13.3 0.3 0.064 12.7 0.3 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A DUF1664 PF07889.12 VBB28677.1 - 0.072 13.1 4.0 0.39 10.8 3.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SdiA-regulated PF06977.11 VBB28677.1 - 0.1 11.8 0.0 2.3 7.4 0.0 2.9 2 1 1 3 3 3 0 SdiA-regulated Phytase-like PF13449.6 VBB28677.1 - 0.11 12.4 0.0 19 5.1 0.0 3.2 2 1 0 3 3 3 0 Esterase-like activity of phytase Imm7 PF15585.6 VBB28677.1 - 0.26 11.6 0.5 0.61 10.4 0.5 1.6 1 0 0 1 1 1 0 Immunity protein 7 KxDL PF10241.9 VBB28677.1 - 1.2 9.5 3.8 2.5 8.4 3.8 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein zf-RING_UBOX PF13445.6 VBB28677.1 - 1.3 9.1 12.3 0.16 12.0 4.7 3.1 2 1 1 3 3 3 0 RING-type zinc-finger Syntaxin-6_N PF09177.11 VBB28677.1 - 3.6 8.2 6.0 37 4.9 4.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal K-box PF01486.17 VBB28677.1 - 6 7.1 7.2 11 6.2 7.2 1.4 1 0 0 1 1 1 0 K-box region JIP_LZII PF16471.5 VBB28677.1 - 7.3 6.9 5.9 1.4 9.1 1.4 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II UPF0561 PF10573.9 VBB28679.1 - 2.2e-10 40.7 0.6 4.2e-10 39.8 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0561 Cyclin_N PF00134.23 VBB28679.1 - 0.0072 16.1 0.4 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Enamelin PF15362.6 VBB28679.1 - 0.0098 14.3 1.7 0.011 14.1 1.7 1.1 1 0 0 1 1 1 1 Enamelin PGBA_C PF15437.6 VBB28679.1 - 0.26 11.6 11.0 0.18 12.2 5.1 2.6 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal FtsL PF04999.13 VBB28679.1 - 1.1 9.3 4.1 1.1 9.3 2.4 1.8 2 0 0 2 2 2 0 Cell division protein FtsL GvpL_GvpF PF06386.11 VBB28679.1 - 4.9 7.0 8.1 2.6 7.9 2.6 2.1 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF GTP1_OBG PF01018.22 VBB28680.1 - 1.7e-46 157.6 7.1 2.3e-46 157.2 7.1 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 VBB28680.1 - 4.1e-22 78.4 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB28680.1 - 1.3e-08 34.5 0.0 4.7e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 VBB28680.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 VBB28680.1 - 0.0062 16.5 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 VBB28680.1 - 0.028 14.0 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 VBB28680.1 - 0.032 14.3 0.0 8.8 6.4 0.0 2.2 1 1 0 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 VBB28680.1 - 0.04 13.9 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 VBB28680.1 - 0.14 12.4 0.0 1.2 9.3 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sec7_N PF12783.7 VBB28683.1 - 3.1e-38 131.2 5.2 6e-38 130.2 4.2 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 VBB28683.1 - 8.4e-37 126.6 0.3 1.9e-36 125.4 0.1 1.8 2 0 0 2 2 2 1 Sec7 domain DCB PF16213.5 VBB28683.1 - 2.9e-26 92.2 0.0 7.9e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 TDA11 PF17084.5 VBB28683.1 - 0.0014 17.6 2.3 0.011 14.7 1.1 2.1 2 0 0 2 2 2 1 Topoisomerase I damage affected protein 11 DUF1955 PF09205.10 VBB28683.1 - 0.046 13.5 3.2 1 9.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) DUF1981 PF09324.10 VBB28684.1 - 3e-30 103.9 13.0 1.1e-29 102.0 0.3 5.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Sec7 PF01369.20 VBB28684.1 - 2.5e-10 40.3 0.1 1.7e-09 37.6 0.1 2.4 2 0 0 2 2 2 1 Sec7 domain FhuF PF06276.12 VBB28684.1 - 0.12 12.8 0.6 0.37 11.2 0.2 2.0 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter Spore_III_AE PF09546.10 VBB28684.1 - 0.24 10.6 4.2 5.8 6.0 0.7 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) HMG_box PF00505.19 VBB28685.1 - 1.5e-14 54.2 0.7 3.2e-14 53.1 0.2 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB28685.1 - 1.6e-09 38.2 0.2 3e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 VBB28685.1 - 0.15 12.7 1.9 0.15 12.6 0.5 1.7 1 1 1 2 2 2 0 YABBY protein GSHPx PF00255.19 VBB28686.1 - 4.2e-62 206.5 4.5 4.4e-37 126.0 0.1 2.9 2 1 0 2 2 2 2 Glutathione peroxidase AhpC-TSA PF00578.21 VBB28686.1 - 1.5e-16 60.5 0.3 9.1e-08 32.1 0.0 2.9 2 2 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 VBB28686.1 - 1.8e-13 50.4 0.4 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Redoxin SCO1-SenC PF02630.14 VBB28686.1 - 0.019 14.9 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 0 SCO1/SenC DUF1573 PF07610.11 VBB28686.1 - 0.12 12.4 0.0 9.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) HSP20 PF00011.21 VBB28687.1 - 3.3e-21 75.3 0.7 4.2e-21 75.0 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pkinase_Tyr PF07714.17 VBB28688.1 - 5.6e-83 278.2 0.0 8e-83 277.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB28688.1 - 3.6e-35 121.6 0.0 5.7e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 VBB28688.1 - 8.5e-15 54.9 5.9 0.0011 19.3 0.0 5.9 6 0 0 6 6 6 3 Fibronectin type III domain fn3_2 PF16893.5 VBB28688.1 - 0.018 15.2 0.0 0.31 11.2 0.0 2.7 2 0 0 2 2 2 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB28688.1 - 0.14 12.8 3.0 15 6.3 1.3 3.2 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain EF1G PF00647.19 VBB28689.1 - 1.1e-49 167.0 0.6 3e-49 165.5 0.6 1.8 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 VBB28689.1 - 1e-08 35.3 1.4 1.3e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain BUD22 PF09073.10 VBB28689.1 - 0.00014 21.4 2.2 0.00017 21.1 2.2 1.1 1 0 0 1 1 1 1 BUD22 GST_C_2 PF13410.6 VBB28689.1 - 0.00066 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 VBB28689.1 - 0.0012 19.1 0.0 0.0056 17.0 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 VBB28689.1 - 0.062 13.5 0.0 0.062 13.5 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF4820 PF16091.5 VBB28689.1 - 0.12 11.7 0.8 0.2 11.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_Rbc25 PF08292.12 VBB28689.1 - 0.4 10.9 3.2 0.84 9.9 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Mcl1_mid PF12341.8 VBB28690.1 - 8.5e-64 215.7 3.2 6.2e-63 212.9 0.5 2.9 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 VBB28690.1 - 2e-08 34.7 14.5 0.16 12.9 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB28690.1 - 1.8e-05 24.9 0.2 1.1 9.6 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB28690.1 - 0.005 16.2 1.1 0.013 14.9 0.3 2.0 2 0 0 2 2 2 1 WD40-like domain TFIIB PF00382.19 VBB28691.1 - 5.3e-43 144.9 7.2 6.4e-22 77.4 0.7 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 VBB28691.1 - 2.5e-13 49.3 0.1 4.1e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 VBB28691.1 - 7.3e-06 25.7 0.1 0.00039 20.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 VBB28691.1 - 0.014 15.5 1.1 2.3 8.3 0.0 2.4 1 1 1 2 2 2 0 Cyclin, C-terminal domain MarR_2 PF12802.7 VBB28691.1 - 0.035 14.0 0.1 14 5.7 0.1 2.5 2 0 0 2 2 2 0 MarR family Guanylin PF02058.15 VBB28691.1 - 0.11 13.0 0.1 1.1 9.8 0.1 2.3 1 1 1 2 2 2 0 Guanylin precursor TFIIB_C_1 PF18542.1 VBB28691.1 - 0.4 10.7 1.5 0.54 10.3 0.2 1.9 2 1 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Nup35_RRM PF05172.13 VBB28692.1 - 3.4e-19 68.7 0.0 7.8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 VBB28692.1 - 2.5e-11 43.4 0.0 3.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Cytochrom_C PF00034.21 VBB28693.1 - 1.1e-12 48.9 0.0 3.2e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 VBB28693.1 - 8.5e-05 22.8 0.0 0.00065 20.0 0.0 2.4 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 VBB28693.1 - 0.00037 20.2 0.4 0.015 15.0 0.0 2.5 2 0 0 2 2 2 1 Cytochrome c-550 domain zf-C2H2_2 PF12756.7 VBB28693.1 - 0.0078 16.5 3.1 0.014 15.7 0.7 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Cytochrome-c551 PF10643.9 VBB28693.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 zf-Di19 PF05605.12 VBB28693.1 - 0.1 12.9 1.4 0.22 11.9 0.6 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 VBB28693.1 - 0.22 12.1 0.4 0.22 12.1 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA PF00004.29 VBB28694.1 - 1.4e-45 155.0 0.0 1.2e-40 139.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 VBB28694.1 - 1.1e-14 54.2 0.1 2.4e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 VBB28694.1 - 6.9e-09 35.4 0.0 2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 VBB28694.1 - 7e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 VBB28694.1 - 2.2e-05 24.2 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 VBB28694.1 - 0.00024 21.6 0.0 0.0013 19.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 VBB28694.1 - 0.00084 19.4 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 VBB28694.1 - 0.0038 17.5 0.5 0.078 13.3 0.2 2.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 VBB28694.1 - 0.0084 16.7 0.2 0.075 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 VBB28694.1 - 0.011 15.0 0.2 0.031 13.5 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 VBB28694.1 - 0.021 15.2 0.0 0.075 13.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 VBB28694.1 - 0.026 14.5 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 VBB28694.1 - 0.026 14.6 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 VBB28694.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 VBB28694.1 - 0.049 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 VBB28694.1 - 0.064 13.8 0.0 0.35 11.4 0.0 2.3 2 0 0 2 2 1 0 ABC transporter RuvB_N PF05496.12 VBB28694.1 - 0.066 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 VBB28694.1 - 0.067 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 VBB28694.1 - 0.1 12.8 0.0 0.46 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 VBB28694.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 VBB28694.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 VBB28694.1 - 0.13 11.7 0.2 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PAS_2 PF08446.11 VBB28694.1 - 0.14 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold AAA_11 PF13086.6 VBB28694.1 - 0.64 9.8 0.0 0.64 9.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF5052 PF16475.5 VBB28695.1 - 0.33 10.6 6.5 0.068 12.8 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5052) Amidase PF01425.21 VBB28696.1 - 1.4e-65 222.1 0.0 4.7e-65 220.3 0.0 1.8 1 1 0 1 1 1 1 Amidase NB-ARC PF00931.22 VBB28696.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SLC12 PF03522.15 VBB28697.1 - 0.059 12.4 3.3 0.063 12.3 3.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 VBB28697.1 - 0.27 9.9 5.2 0.3 9.8 5.2 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 VBB28697.1 - 0.28 9.7 7.3 0.32 9.5 7.3 1.0 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 VBB28697.1 - 0.29 10.5 5.2 0.35 10.3 5.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SID-1_RNA_chan PF13965.6 VBB28697.1 - 0.34 9.2 0.4 0.37 9.1 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GREB1 PF15782.5 VBB28697.1 - 0.57 7.2 7.8 0.67 7.0 7.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 VBB28697.1 - 5.9 5.6 9.8 6.5 5.4 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hydin_ADK PF17213.3 VBB28697.1 - 7.1 6.9 9.7 21 5.3 9.7 1.7 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain ALMT PF11744.8 VBB28697.1 - 9.7 4.9 5.6 11 4.7 5.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cadherin PF00028.17 VBB28698.1 - 7.8e-14 51.9 0.0 1.3e-10 41.5 0.0 3.2 3 0 0 3 3 3 2 Cadherin domain HemY_N PF07219.13 VBB28698.1 - 0.025 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Adaptin_N PF01602.20 VBB28699.1 - 7.6e-110 367.9 10.6 7.6e-110 367.9 10.6 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 VBB28699.1 - 7.3e-55 184.4 0.0 3.1e-54 182.4 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 VBB28699.1 - 2e-52 176.8 0.2 4.9e-52 175.6 0.2 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 VBB28699.1 - 2.9e-08 33.9 9.4 7.1e-08 32.7 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 VBB28699.1 - 1.9e-07 31.3 2.9 0.0029 17.9 0.0 4.9 3 2 2 5 5 5 1 HEAT repeats HEAT PF02985.22 VBB28699.1 - 8.8e-06 25.6 1.0 0.21 11.9 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 VBB28699.1 - 0.0012 19.3 2.3 3.6 8.2 0.0 4.1 4 0 0 4 4 4 2 HEAT-like repeat Arm PF00514.23 VBB28699.1 - 0.002 18.1 0.2 12 6.1 0.0 3.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 VBB28699.1 - 0.071 12.7 1.6 1.1 8.7 0.0 3.1 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF5578 PF17741.1 VBB28699.1 - 0.16 11.4 4.1 1.8 7.9 0.2 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5578) Vac14_Fab1_bd PF12755.7 VBB28699.1 - 0.25 11.9 3.5 11 6.7 0.0 4.4 3 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region eIF3_N PF09440.10 VBB28699.1 - 1 9.8 3.6 0.61 10.5 0.5 2.2 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain Peptidase_C48 PF02902.19 VBB28700.1 - 5.3e-36 124.5 0.2 8.5e-36 123.8 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Proteasome PF00227.26 VBB28701.1 - 1.4e-41 142.1 0.1 1.6e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_S21 PF01165.20 VBB28702.1 - 1.5e-08 34.2 0.1 2.8e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S21 tRNA-synt_1 PF00133.22 VBB28703.1 - 3.1e-38 131.4 0.0 1.2e-17 63.4 0.0 3.3 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 VBB28703.1 - 2e-13 49.9 0.0 8.2e-07 28.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 VBB28703.1 - 2.3e-10 40.6 0.0 6.8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 VBB28703.1 - 4.8e-06 26.2 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.27 VBB28704.1 - 2.9e-59 197.0 2.0 1.2e-19 70.0 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ECF_trnsprt PF12822.7 VBB28704.1 - 0.058 13.5 0.1 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Serine_protease PF18405.1 VBB28704.1 - 0.066 12.4 0.6 0.27 10.4 0.3 2.2 1 1 1 2 2 2 0 Gammaproteobacterial serine protease LapA_dom PF06305.11 VBB28704.1 - 0.073 12.9 0.2 20 5.1 0.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PEPCK_GTP PF00821.18 VBB28705.1 - 2.5e-164 546.3 0.2 3.1e-164 546.0 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 VBB28705.1 - 3.5e-93 311.2 0.0 4.7e-93 310.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain SIT PF15330.6 VBB28706.1 - 0.08 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT BSMAP PF12280.8 VBB28706.1 - 0.35 11.1 3.0 0.13 12.5 0.5 1.5 1 1 1 2 2 2 0 Brain specific membrane anchored protein Pep1_7 PF17232.2 VBB28707.1 - 0.017 15.6 8.6 0.086 13.3 8.2 2.1 1 1 0 2 2 2 0 Elicitor peptide 1-7 NAM-associated PF14303.6 VBB28707.1 - 0.043 14.5 0.8 0.049 14.4 0.8 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SSP160 PF06933.11 VBB28707.1 - 0.15 10.2 28.2 0.17 10.1 28.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF5534 PF17686.1 VBB28707.1 - 0.26 11.5 1.4 0.32 11.2 1.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5534) AJAP1_PANP_C PF15298.6 VBB28707.1 - 0.33 11.2 15.6 0.41 10.8 15.6 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF5521 PF17659.1 VBB28707.1 - 0.37 8.6 3.6 0.42 8.4 3.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) TMEM154 PF15102.6 VBB28707.1 - 0.54 10.2 8.0 0.7 9.8 8.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family TrbC PF04956.13 VBB28707.1 - 0.62 10.3 5.2 5.2 7.3 0.1 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Dicty_REP PF05086.12 VBB28707.1 - 1.4 6.8 8.8 1.5 6.7 8.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.22 VBB28708.1 - 7.3e-63 211.0 0.2 9.2e-63 210.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB28708.1 - 5.5e-35 120.2 0.1 8.7e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28708.1 - 1.1e-12 47.7 0.1 2.6e-12 46.5 0.1 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB28708.1 - 3.7e-07 30.2 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 VBB28708.1 - 8.9e-05 22.1 0.1 0.00039 20.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB28708.1 - 0.00017 21.6 0.4 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 VBB28708.1 - 0.0003 21.1 0.0 0.0053 17.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 VBB28708.1 - 0.0039 16.6 0.1 0.0069 15.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 VBB28708.1 - 0.018 15.4 0.1 0.032 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 VBB28708.1 - 0.032 13.7 0.0 0.057 12.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 VBB28708.1 - 0.046 14.2 0.1 0.083 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 VBB28708.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain FAD-SLDH PF12318.8 VBB28708.1 - 0.058 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase TniB PF05621.11 VBB28708.1 - 0.081 12.3 0.1 0.26 10.7 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 VBB28708.1 - 0.089 12.5 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 VBB28708.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Ribosomal_L30_N PF08079.12 VBB28709.1 - 1.1e-21 76.8 18.2 2.1e-21 76.0 18.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 VBB28709.1 - 1e-20 73.3 1.6 3e-20 71.8 1.6 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e ABC1 PF03109.16 VBB28709.1 - 0.0025 18.0 0.6 0.0043 17.2 0.6 1.3 1 0 0 1 1 1 1 ABC1 family CHCH PF06747.13 VBB28711.1 - 6.3e-08 32.6 5.2 9.6e-08 32.0 5.2 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 VBB28711.1 - 0.025 14.8 2.6 0.041 14.2 2.6 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Defensin_1 PF00323.19 VBB28711.1 - 0.068 13.7 2.1 0.38 11.4 0.1 2.2 2 1 0 2 2 2 0 Mammalian defensin CR6_interact PF10147.9 VBB28713.1 - 2.6e-22 79.5 8.0 2.6e-22 79.5 8.0 2.0 1 1 1 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF724 PF05266.14 VBB28713.1 - 0.00055 19.8 7.5 0.044 13.6 0.1 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF724) NAP PF00956.18 VBB28713.1 - 0.015 14.5 6.2 0.021 14.0 6.2 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF501 PF04417.12 VBB28713.1 - 5.1 6.9 5.5 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF501) ATE_C PF04377.15 VBB28714.1 - 2.2e-43 148.1 7.9 2.2e-43 148.1 5.2 2.3 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 VBB28714.1 - 3.3e-22 78.7 2.0 1e-21 77.1 2.0 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF4481 PF14800.6 VBB28714.1 - 0.28 10.6 1.8 0.53 9.7 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4481) Mob1_phocein PF03637.17 VBB28716.1 - 2.7e-71 239.0 0.0 3.2e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Zip PF02535.22 VBB28717.1 - 3.5e-39 135.0 12.4 4.4e-16 59.0 0.2 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter TMEM107 PF14995.6 VBB28717.1 - 0.012 16.0 0.9 0.043 14.2 0.0 2.5 3 0 0 3 3 3 0 Transmembrane protein CopD PF05425.13 VBB28717.1 - 0.45 10.9 6.7 6.3 7.3 1.2 2.7 2 0 0 2 2 2 0 Copper resistance protein D CRCB PF02537.15 VBB28717.1 - 2.6 8.4 10.2 0.6 10.5 1.3 3.2 3 1 0 3 3 3 0 CrcB-like protein, Camphor Resistance (CrcB) PHO4 PF01384.20 VBB28719.1 - 1.1e-123 412.6 12.2 1.6e-123 412.1 12.2 1.2 1 0 0 1 1 1 1 Phosphate transporter family COX6C PF02937.15 VBB28719.1 - 0.19 11.9 0.0 0.66 10.2 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DSPc PF00782.20 VBB28720.1 - 1.1e-11 44.6 0.0 2.6e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB28720.1 - 4.9e-09 36.1 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 VBB28720.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 VBB28720.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family RRN3 PF05327.11 VBB28723.1 - 1.3 7.5 16.8 1.9 6.9 16.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_L5 PF00281.19 VBB28724.1 - 2.2e-22 79.1 0.0 1.3e-21 76.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 VBB28724.1 - 6.5e-20 71.1 0.0 1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus V-ATPase_H_N PF03224.14 VBB28725.1 - 2.7e-96 322.6 7.4 3.6e-96 322.2 7.4 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 VBB28725.1 - 6.8e-22 77.8 3.2 1e-21 77.2 0.2 2.6 2 1 1 3 3 3 1 V-ATPase subunit H Arm PF00514.23 VBB28725.1 - 0.0019 18.2 0.0 0.063 13.3 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 VBB28725.1 - 0.033 14.6 0.1 0.32 11.4 0.0 2.6 2 1 0 2 2 2 0 HEAT repeats DUF4704 PF15787.5 VBB28725.1 - 0.035 13.4 1.8 0.28 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) RIH_assoc PF08454.11 VBB28725.1 - 0.16 11.8 2.0 0.32 10.9 0.3 2.4 2 0 0 2 2 2 0 RyR and IP3R Homology associated Cyt-b5 PF00173.28 VBB28725.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 VBB28725.1 - 0.55 10.3 2.3 9.4 6.3 0.0 3.0 2 1 0 3 3 3 0 Ferric reductase NAD binding domain Reprolysin_5 PF13688.6 VBB28726.1 - 8.4e-33 114.2 0.7 2.1e-32 112.9 0.7 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 VBB28726.1 - 4.5e-32 111.5 0.6 7.6e-32 110.8 0.1 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 VBB28726.1 - 1.6e-16 60.9 0.3 2.8e-16 60.1 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 VBB28726.1 - 1.2e-15 58.0 16.6 1.2e-15 58.0 16.6 3.3 2 1 0 2 2 2 1 Disintegrin ADAM17_MPD PF16698.5 VBB28726.1 - 2.7e-12 46.9 13.5 2.7e-12 46.9 13.5 3.7 2 1 1 3 3 3 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin_4 PF13583.6 VBB28726.1 - 8.8e-10 38.6 1.1 9.9e-08 31.9 1.1 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 VBB28726.1 - 7e-06 26.3 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 VBB28726.1 - 7.5e-06 26.0 0.0 0.0038 17.1 0.0 3.2 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Glutaminase PF04960.15 VBB28727.1 - 2.4e-44 151.6 0.1 3.2e-44 151.2 0.1 1.2 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 VBB28727.1 - 9.5e-11 42.2 0.0 1.6e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB28727.1 - 3e-06 27.6 0.0 9.9e-06 26.0 0.0 1.9 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB28727.1 - 2.5e-05 24.5 0.0 0.0091 16.4 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 VBB28727.1 - 0.0003 21.0 0.0 0.0037 17.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 VBB28727.1 - 0.001 19.3 0.1 0.0052 17.1 0.0 2.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Glutaminase PF04960.15 VBB28728.1 - 8.3e-57 192.5 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 VBB28728.1 - 5.3e-27 94.0 0.0 8.8e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain wnt PF00110.19 VBB28729.1 - 4.4e-92 309.0 26.0 4.4e-92 309.0 26.0 1.9 2 0 0 2 2 2 1 wnt family Pkinase PF00069.25 VBB28729.1 - 6.2e-32 111.0 0.2 1.1e-31 110.2 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28729.1 - 1e-30 106.9 2.2 3e-29 102.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Activin_recp PF01064.23 VBB28729.1 - 6e-09 36.9 6.3 6e-09 36.9 6.3 3.5 4 0 0 4 4 4 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 VBB28729.1 - 2.9e-05 23.1 0.0 2.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase TGF_beta_GS PF08515.12 VBB28729.1 - 0.0033 16.9 0.3 0.0033 16.9 0.3 2.8 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif APH PF01636.23 VBB28729.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 VBB28729.1 - 0.019 14.6 0.0 0.085 12.5 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glycogen_syn PF05693.13 VBB28731.1 - 2.5e-18 66.0 0.0 3.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase SNF PF00209.18 VBB28732.1 - 1.5e-11 43.7 3.8 1.7e-11 43.5 3.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF2_N PF00176.23 VBB28733.1 - 5.4e-49 166.8 0.1 1.1e-48 165.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB28733.1 - 1.5e-14 54.3 1.1 9.8e-14 51.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB28733.1 - 3.3e-09 37.0 0.0 3.3e-09 37.0 0.0 3.5 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit RGS PF00615.19 VBB28734.1 - 2.4e-09 37.5 0.3 4.7e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DIX PF00778.17 VBB28734.1 - 3.8e-09 36.2 0.0 5.9e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 DIX domain Peptidase_C2 PF00648.21 VBB28736.1 - 2.2e-122 407.7 0.0 2.8e-122 407.4 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 VBB28736.1 - 2.8e-40 137.8 0.0 4.9e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III ATG13 PF10033.9 VBB28737.1 - 0.00047 19.9 0.0 0.009 15.7 0.0 2.6 1 1 1 2 2 2 1 Autophagy-related protein 13 Frag1 PF10277.9 VBB28738.1 - 1.8e-47 161.7 15.5 2e-47 161.5 15.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family COX15-CtaA PF02628.15 VBB28738.1 - 7.9e-06 25.2 1.3 1.2e-05 24.6 1.3 1.3 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Claudin_3 PF06653.11 VBB28738.1 - 0.00012 22.0 10.8 0.051 13.5 1.1 2.4 1 1 1 2 2 2 2 Tight junction protein, Claudin-like Peptidase_U4 PF03419.13 VBB28738.1 - 1.5 8.0 11.2 0.52 9.6 8.1 1.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Ets PF00178.22 VBB28739.1 - 6.8e-30 103.4 0.0 1.3e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 VBB28739.1 - 1.4e-08 34.6 0.1 5.2e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Tetraspanin PF00335.20 VBB28740.1 - 2.4e-32 112.5 7.1 3.2e-32 112.1 7.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Ras PF00071.22 VBB28741.1 - 6.9e-54 181.8 0.0 2.7e-52 176.7 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB28741.1 - 1.2e-20 73.9 0.0 7.8e-20 71.3 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28741.1 - 6.9e-07 28.9 0.0 1.4e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 VBB28741.1 - 0.071 13.3 0.0 3 8.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 VBB28742.1 - 3.7e-52 176.2 0.0 4.6e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB28742.1 - 1.8e-18 66.9 0.0 2.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28742.1 - 5.5e-08 32.5 0.0 1.1e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB28742.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PLDc PF00614.22 VBB28743.1 - 6.2e-17 61.0 2.5 3.5e-08 33.3 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 VBB28743.1 - 2.3e-12 46.9 0.2 6.3e-07 29.3 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 VBB28743.1 - 6.1e-09 35.9 0.2 0.0028 17.6 0.0 3.4 3 0 0 3 3 3 2 PX domain PH PF00169.29 VBB28743.1 - 4.6e-05 23.9 0.1 0.00014 22.3 0.1 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 VBB28743.1 - 1.4 9.4 5.9 1.4 9.3 0.9 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain FERM_F2 PF18377.1 VBB28744.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain PAS_11 PF14598.6 VBB28745.1 - 1.2e-17 64.1 0.2 3.7e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 VBB28745.1 - 1.6e-14 54.0 0.0 5.3e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 VBB28745.1 - 1.8e-13 50.4 0.0 2.7e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 VBB28745.1 - 0.00033 20.9 0.0 0.013 15.7 0.0 2.5 2 1 0 2 2 2 1 PAS domain HLH PF00010.26 VBB28745.1 - 0.0011 18.8 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 VBB28745.1 - 0.0014 18.8 0.0 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_2 PF08446.11 VBB28745.1 - 0.022 15.4 0.2 5.8 7.6 0.0 2.3 2 0 0 2 2 2 0 PAS fold DUF4144 PF13642.6 VBB28745.1 - 0.028 15.0 0.2 4 8.1 0.0 2.5 2 0 0 2 2 2 0 protein structure with unknown function SprT-like PF10263.9 VBB28746.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 SprT-like family DUF281 PF03436.13 VBB28746.1 - 0.071 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF281) Arf PF00025.21 VBB28747.1 - 2.2e-64 216.1 1.6 4.6e-47 159.7 0.4 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family eIF3g PF12353.8 VBB28747.1 - 2e-30 105.7 1.5 3.7e-30 104.9 1.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 VBB28747.1 - 1.6e-19 69.5 0.1 5.2e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-alpha PF00503.20 VBB28747.1 - 3.6e-11 42.8 3.3 3.4e-07 29.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 VBB28747.1 - 2.8e-10 40.5 0.1 6.5e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB28747.1 - 3e-08 33.4 0.0 3.2e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 VBB28747.1 - 1.6e-07 30.9 0.0 2.3e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 VBB28747.1 - 2.1e-06 27.2 0.0 3.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB28747.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_5 PF13893.6 VBB28747.1 - 0.047 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FeoB_N PF02421.18 VBB28747.1 - 0.11 12.1 0.1 0.31 10.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PHM7_cyt PF14703.6 VBB28747.1 - 0.13 12.5 0.1 1.4 9.1 0.1 2.3 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4585 PF15232.6 VBB28748.1 - 0.11 12.6 1.5 0.39 10.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4585) TBCC_N PF16752.5 VBB28748.1 - 0.78 10.2 4.0 1.7 9.1 0.0 2.9 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain IpaB_EvcA PF03278.13 VBB28749.1 - 0.16 11.7 0.4 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 IpaB/EvcA family DUF4123 PF13503.6 VBB28749.1 - 0.17 12.3 1.2 0.35 11.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) Hydrolase_2 PF07486.12 VBB28749.1 - 0.2 12.5 0.5 0.71 10.8 0.1 2.1 2 0 0 2 2 2 0 Cell Wall Hydrolase DEAD PF00270.29 VBB28750.1 - 1e-44 152.4 0.0 1.6e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB28750.1 - 5.8e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GATase_2 PF00310.21 VBB28752.1 - 3.5e-19 68.8 1.6 5.4e-12 45.1 0.3 2.0 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Kelch_5 PF13854.6 VBB28753.1 - 4.1e-19 68.1 9.1 4e-05 23.5 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 VBB28753.1 - 3.5e-15 55.3 9.2 0.022 14.4 0.2 6.0 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 VBB28753.1 - 1e-14 54.2 6.2 9.8e-05 22.3 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 VBB28753.1 - 2.7e-14 52.5 10.9 0.13 12.3 0.0 6.6 6 0 0 6 6 6 5 Kelch motif CUB PF00431.20 VBB28753.1 - 2.2e-12 47.3 0.4 1.1e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 CUB domain Kelch_6 PF13964.6 VBB28753.1 - 5.3e-09 36.1 11.5 0.023 15.0 0.1 6.6 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 VBB28753.1 - 2.5e-07 30.8 10.2 0.0039 17.4 0.0 6.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Laminin_EGF PF00053.24 VBB28753.1 - 3.2e-07 30.4 40.0 6.3e-05 23.0 16.8 8.5 9 1 1 10 10 7 3 Laminin EGF domain PSI_integrin PF17205.3 VBB28753.1 - 4.2e-06 26.4 3.5 4.2e-06 26.4 3.5 7.5 8 0 0 8 8 7 1 Integrin plexin domain PSI PF01437.25 VBB28753.1 - 7.8e-05 23.1 32.5 0.00064 20.2 12.9 8.7 9 2 1 10 10 7 3 Plexin repeat EGF_2 PF07974.13 VBB28753.1 - 0.0037 17.6 27.6 0.0047 17.3 13.0 9.9 9 1 1 10 10 8 4 EGF-like domain Saf_2TM PF18303.1 VBB28753.1 - 0.029 13.9 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Homeodomain PF00046.29 VBB28754.1 - 2.8e-21 75.1 6.1 4.2e-21 74.5 6.1 1.3 1 0 0 1 1 1 1 Homeodomain PCSK9_C1 PF18459.1 VBB28754.1 - 0.19 11.9 1.0 0.49 10.6 1.0 1.7 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Auxin_canalis PF05703.11 VBB28754.1 - 1.7 8.5 9.9 2.6 7.9 9.9 1.5 1 1 0 1 1 1 0 Auxin canalisation Cadherin PF00028.17 VBB28755.1 - 1.2e-188 612.3 30.2 2.1e-19 69.7 0.0 18.3 17 1 1 18 18 18 17 Cadherin domain Cadherin_2 PF08266.12 VBB28755.1 - 1.8e-12 46.9 0.3 1.1 9.2 0.0 10.5 10 0 0 10 10 10 3 Cadherin-like Cadherin_pro PF08758.11 VBB28755.1 - 2.6e-12 46.7 0.2 0.16 12.1 0.0 9.2 8 0 0 8 8 8 2 Cadherin prodomain like Cadherin_3 PF16184.5 VBB28755.1 - 3.6e-10 39.8 9.5 0.42 10.6 0.1 10.2 11 0 0 11 11 11 2 Cadherin-like RET_CLD1 PF17756.1 VBB28755.1 - 1.7e-07 31.5 2.4 18 5.6 0.0 10.0 12 0 0 12 12 12 1 RET Cadherin like domain 1 TMEM154 PF15102.6 VBB28755.1 - 0.027 14.4 1.8 0.043 13.7 0.5 2.0 2 0 0 2 2 2 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 VBB28755.1 - 0.15 12.3 0.8 0.3 11.3 0.8 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Oscp1 PF10188.9 VBB28756.1 - 5.9e-59 199.1 10.7 9e-59 198.5 10.7 1.3 1 0 0 1 1 1 1 Organic solute transport protein 1 DUF1002 PF06207.11 VBB28756.1 - 1.2 8.6 4.2 1.9 8.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Cadherin PF00028.17 VBB28757.1 - 3.5e-59 197.3 0.2 1.1e-13 51.4 0.0 5.9 6 0 0 6 6 6 5 Cadherin domain Cadherin_3 PF16184.5 VBB28757.1 - 0.0079 16.2 0.2 18 5.4 0.0 3.5 3 0 0 3 3 3 2 Cadherin-like RRM_2 PF04059.12 VBB28757.1 - 0.13 12.5 0.0 25 5.2 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif 2 BK_channel_a PF03493.18 VBB28759.1 - 3.5e-50 168.2 0.0 2.7e-34 117.3 0.0 2.5 1 1 1 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 VBB28759.1 - 3.3e-17 62.6 14.6 6.7e-17 61.5 14.6 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 VBB28759.1 - 3.7e-14 52.4 6.7 3.7e-14 52.4 6.7 2.1 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 VBB28759.1 - 0.0041 17.0 0.2 0.0082 16.0 0.2 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel TrkA_N PF02254.18 VBB28759.1 - 0.03 14.6 0.1 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain polyprenyl_synt PF00348.17 VBB28760.1 - 1.7e-60 204.3 0.2 2.2e-60 203.9 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4898 PF16239.5 VBB28760.1 - 0.07 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) Prp18 PF02840.15 VBB28761.1 - 4.2e-53 179.2 0.3 4.2e-53 179.2 0.3 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 VBB28761.1 - 1.7e-12 46.6 1.0 3.1e-12 45.8 1.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like MCU PF04678.13 VBB28762.1 - 6.1e-45 153.5 2.7 7.6e-45 153.1 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter APG6_N PF17675.1 VBB28763.1 - 2.9 8.4 10.5 16 6.0 0.3 3.2 1 1 0 2 2 2 0 Apg6 coiled-coil region CCDC92 PF14916.6 VBB28764.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF2508 PF10704.9 VBB28764.1 - 0.059 13.6 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Herpes_BLRF2 PF05812.12 VBB28764.1 - 0.085 13.0 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Mto2_bdg PF12808.7 VBB28764.1 - 7.8 6.9 8.7 5.1 7.5 0.1 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region UPF0183 PF03676.14 VBB28765.1 - 6.5e-130 433.9 0.0 8.8e-130 433.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Metallophos PF00149.28 VBB28765.1 - 1.2e-15 58.6 0.1 2e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DOMON PF03351.17 VBB28766.1 - 5e-09 36.4 0.0 7.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 VBB28766.1 - 1.1e-07 32.1 5.5 1.1e-07 32.1 5.5 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 SUR7 PF06687.12 VBB28766.1 - 0.00032 20.4 10.1 0.17 11.4 0.0 3.6 2 1 1 3 3 3 2 SUR7/PalI family DUF373 PF04123.13 VBB28766.1 - 0.45 9.9 12.3 0.81 9.1 12.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_3_6 PF07332.11 VBB28766.1 - 0.61 10.1 15.4 5.6 7.0 5.7 3.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ldl_recept_a PF00057.18 VBB28766.1 - 1.9 8.8 4.7 3.8 7.8 4.7 1.4 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A AA_permease_2 PF13520.6 VBB28767.1 - 3.3e-65 220.6 46.1 4.2e-65 220.3 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 VBB28767.1 - 1e-30 106.8 40.2 1.5e-30 106.3 40.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 VBB28767.1 - 0.17 12.0 8.9 0.11 12.6 2.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF962) AAA PF00004.29 VBB28768.1 - 1.7e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 VBB28768.1 - 1.2e-25 89.2 0.5 5.4e-25 87.2 0.1 2.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 VBB28768.1 - 1e-08 34.8 0.0 2.8e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 VBB28768.1 - 5.4e-06 26.7 0.1 0.0028 17.9 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 VBB28768.1 - 9.2e-06 25.7 0.0 2.7e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB28768.1 - 1.4e-05 25.6 0.0 0.0012 19.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 VBB28768.1 - 3.3e-05 23.7 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 VBB28768.1 - 5.1e-05 22.6 0.0 8.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 VBB28768.1 - 7.1e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 VBB28768.1 - 8.5e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 VBB28768.1 - 0.00013 22.2 0.0 0.00033 20.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 VBB28768.1 - 0.0007 20.1 0.0 0.0015 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 VBB28768.1 - 0.00078 19.8 0.1 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 VBB28768.1 - 0.002 17.3 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 VBB28768.1 - 0.0028 17.1 0.0 1.4 8.3 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein AAA_33 PF13671.6 VBB28768.1 - 0.0042 17.3 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 VBB28768.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 VBB28768.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 VBB28768.1 - 0.012 16.0 0.0 0.049 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 VBB28768.1 - 0.013 14.9 0.3 1.2 8.5 0.1 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 VBB28768.1 - 0.018 14.8 0.0 0.075 12.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 VBB28768.1 - 0.018 14.6 0.1 1.7 8.2 0.1 2.4 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 VBB28768.1 - 0.019 14.2 0.0 0.74 9.1 0.0 2.5 1 1 1 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 VBB28768.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 VBB28768.1 - 0.023 14.1 0.0 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 VBB28768.1 - 0.029 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 VBB28768.1 - 0.076 12.9 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 VBB28768.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 VBB28768.1 - 0.1 12.3 0.1 0.58 9.8 0.0 2.2 2 1 0 3 3 3 0 Guanylate kinase MCM PF00493.23 VBB28768.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ResIII PF04851.15 VBB28768.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 VBB28768.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 7tm_1 PF00001.21 VBB28769.1 - 5.3e-05 22.7 24.7 0.00027 20.3 24.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIT PF04212.18 VBB28770.1 - 4.6e-25 87.5 5.5 4.6e-25 87.5 5.5 2.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Tae4 PF14113.6 VBB28770.1 - 0.062 13.5 0.2 0.084 13.1 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 DUF2749 PF10907.8 VBB28771.1 - 0.11 12.6 7.7 0.071 13.3 5.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) DUF3824 PF12868.7 VBB28771.1 - 1.5 9.5 11.2 1.7 9.3 11.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) C6 PF01681.17 VBB28772.1 - 0.3 11.6 8.0 0.66 10.5 8.0 1.6 1 1 0 1 1 1 0 C6 domain NDUFA12 PF05071.16 VBB28773.1 - 2.4e-22 79.6 3.5 4.8e-22 78.6 3.5 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SEP PF08059.13 VBB28773.1 - 1.9e-19 70.0 0.0 3.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 VBB28773.1 - 3.8e-12 46.2 0.0 1.1e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 UBX domain HrpB7 PF09486.10 VBB28774.1 - 0.0083 16.5 0.6 0.15 12.4 0.1 2.1 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) Laminin_I PF06008.14 VBB28774.1 - 0.058 13.1 5.9 0.99 9.1 0.1 2.1 1 1 1 2 2 2 0 Laminin Domain I Sec34 PF04136.15 VBB28774.1 - 0.074 12.9 5.2 0.59 10.0 0.3 2.2 1 1 1 2 2 2 0 Sec34-like family bZIP_1 PF00170.21 VBB28774.1 - 0.079 13.1 8.3 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor CALCOCO1 PF07888.11 VBB28774.1 - 0.088 11.7 9.8 0.12 11.2 9.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1S3 PF15753.5 VBB28774.1 - 0.099 12.8 2.5 0.1 12.7 1.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF948 PF06103.11 VBB28774.1 - 0.11 12.8 2.8 1.5 9.1 1.7 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TLE_N PF03920.15 VBB28774.1 - 0.14 12.3 7.5 0.35 11.0 7.5 1.7 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain ApoO PF09769.9 VBB28774.1 - 0.26 11.2 1.9 0.55 10.2 0.2 2.0 1 1 1 2 2 2 0 Apolipoprotein O Tweety PF04906.13 VBB28774.1 - 0.3 9.7 4.1 0.48 9.0 3.6 1.5 1 1 0 1 1 1 0 Tweety DUF745 PF05335.13 VBB28774.1 - 0.82 9.4 4.2 1.3 8.7 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) SKA2 PF16740.5 VBB28774.1 - 0.87 9.4 8.8 0.84 9.5 2.0 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 VBB28774.1 - 2.2 8.4 10.0 4.3 7.5 9.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0449 PF15136.6 VBB28774.1 - 8.4 6.9 9.1 20 5.7 4.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 I_LWEQ PF01608.17 VBB28774.1 - 8.8 6.6 11.8 3.9 7.7 6.9 2.2 1 1 1 2 2 2 0 I/LWEQ domain Laminin_G_2 PF02210.24 VBB28775.1 - 4.5e-33 114.5 7.8 3e-18 66.6 0.0 5.0 4 2 0 4 4 4 3 Laminin G domain Laminin_G_1 PF00054.23 VBB28775.1 - 5.4e-27 94.6 0.1 3.3e-13 50.0 0.0 4.6 4 1 0 4 4 4 3 Laminin G domain Laminin_G_3 PF13385.6 VBB28775.1 - 1.4e-10 41.6 1.4 6.6e-05 23.1 0.0 3.5 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 VBB28775.1 - 1.8e-05 25.0 4.8 1.8e-05 25.0 4.8 3.7 3 0 0 3 3 3 2 EGF-like domain DEAD PF00270.29 VBB28777.1 - 8.2e-45 152.7 0.2 1.4e-44 151.9 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB28777.1 - 1.1e-28 99.7 0.1 6e-28 97.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB28777.1 - 7.4e-05 22.8 0.5 0.00044 20.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4246 PF14033.6 VBB28777.1 - 0.087 11.9 0.9 0.15 11.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Peptidase_S8 PF00082.22 VBB28778.1 - 3.4e-78 262.9 0.0 4.9e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 VBB28778.1 - 1e-58 198.0 0.0 1.9e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II TPPII_N PF12583.8 VBB28778.1 - 0.027 15.0 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Pkip-1 PF06878.11 VBB28778.1 - 0.1 12.7 0.2 0.24 11.5 0.2 1.6 1 0 0 1 1 1 0 Pkip-1 protein Pro_isomerase PF00160.21 VBB28779.1 - 9.4e-47 159.2 0.3 2.8e-46 157.7 0.3 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCR_14kD PF02271.16 VBB28780.1 - 3.7e-21 74.9 0.1 5.3e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit RrnaAD PF00398.20 VBB28780.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pkinase PF00069.25 VBB28781.1 - 0.0024 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2368 PF10166.9 VBB28782.1 - 2.4e-23 82.2 3.0 4.4e-11 42.5 0.3 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2368) Ufd2P_core PF10408.9 VBB28783.1 - 2.2e-160 535.3 12.5 2.7e-160 535.0 12.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 VBB28783.1 - 1.9e-28 98.4 0.8 2.1e-27 95.1 0.5 2.5 2 0 0 2 2 2 1 U-box domain E1_dh PF00676.20 VBB28784.1 - 8.2e-112 373.0 0.0 1e-111 372.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 VBB28784.1 - 0.026 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 VBB28784.1 - 0.073 12.8 0.8 0.13 12.0 0.8 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4549 PF15082.6 VBB28785.1 - 0.035 13.9 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) DUF3439 PF11921.8 VBB28785.1 - 0.97 9.4 11.7 0.1 12.6 7.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HGTP_anticodon PF03129.20 VBB28786.1 - 2.4e-14 53.2 0.0 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 VBB28786.1 - 3.6e-10 40.1 0.2 1.1e-09 38.5 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 VBB28786.1 - 6e-10 39.1 3.4 1.7e-09 37.7 3.4 1.8 1 0 0 1 1 1 1 WHEP-TRS domain YppF PF14178.6 VBB28786.1 - 0.46 10.4 2.1 5.5 6.9 0.0 3.3 3 0 0 3 3 3 0 YppF-like protein Rpn3_C PF08375.11 VBB28787.1 - 9.9e-25 86.8 1.5 9.9e-25 86.8 1.5 2.5 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 VBB28787.1 - 4.8e-18 65.6 0.1 4.8e-18 65.6 0.1 2.3 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 VBB28787.1 - 0.0093 16.0 5.7 0.13 12.5 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 VBB28787.1 - 0.038 14.0 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_19 PF14559.6 VBB28787.1 - 0.15 12.6 1.3 1.8 9.1 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 VBB28787.1 - 0.18 12.4 3.7 6.3 7.5 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CKAP2_C PF15297.6 VBB28787.1 - 1.5 7.8 8.5 0.046 12.8 0.6 2.0 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus TPR_1 PF00515.28 VBB28787.1 - 3.2 7.7 6.7 12 5.9 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L32p PF01783.23 VBB28788.1 - 0.0045 17.2 1.8 0.0045 17.2 1.8 1.7 2 0 0 2 2 2 1 Ribosomal L32p protein family RecR PF02132.15 VBB28788.1 - 0.017 14.7 0.9 0.047 13.3 0.9 1.7 1 0 0 1 1 1 0 RecR protein OHCU_decarbox PF09349.10 VBB28788.1 - 0.025 15.1 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 OHCU decarboxylase zinc-ribbons_6 PF07191.12 VBB28788.1 - 0.054 13.5 2.1 0.095 12.7 2.1 1.4 1 0 0 1 1 1 0 zinc-ribbons Pkinase_Tyr PF07714.17 VBB28789.1 - 5e-53 180.0 0.0 7.5e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB28789.1 - 2.3e-40 138.6 0.0 3.5e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAM_KSR1 PF13543.6 VBB28789.1 - 1.1e-06 28.8 0.2 2.2e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 VBB28789.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C1_1 PF00130.22 VBB28789.1 - 0.02 14.7 13.4 0.037 13.9 13.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 VBB28789.1 - 0.048 13.0 0.5 0.11 11.8 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 VBB28789.1 - 0.4 11.0 5.8 1 9.7 5.8 1.7 1 0 0 1 1 1 0 C1 domain HSP70 PF00012.20 VBB28790.1 - 1.6e-174 581.5 1.5 1.6e-174 581.5 1.5 1.6 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 VBB28790.1 - 2.5e-05 23.3 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 VBB28790.1 - 0.003 17.3 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SNF PF00209.18 VBB28791.1 - 1.2e-37 129.8 3.5 6e-31 107.7 0.3 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family PHD PF00628.29 VBB28792.1 - 5.9e-08 32.5 4.7 5.9e-08 32.5 4.7 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 VBB28792.1 - 2.9e-05 23.5 8.6 2.9e-05 23.5 8.6 3.0 3 1 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 VBB28792.1 - 0.0004 20.3 1.2 0.0004 20.3 1.2 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF1451 PF07295.11 VBB28792.1 - 0.0087 16.1 0.4 0.015 15.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon containing domain Nop14 PF04147.12 VBB28792.1 - 0.025 12.8 4.1 0.028 12.6 4.1 1.0 1 0 0 1 1 1 0 Nop14-like family C1_1 PF00130.22 VBB28792.1 - 0.027 14.4 0.9 0.027 14.4 0.9 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 VBB28792.1 - 0.031 14.5 1.4 0.031 14.5 1.4 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain Gemin7 PF11095.8 VBB28792.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF2318 PF10080.9 VBB28792.1 - 0.058 13.5 0.9 0.058 13.5 0.9 1.7 2 0 0 2 2 1 0 Predicted membrane protein (DUF2318) zf-HC5HC2H_2 PF13832.6 VBB28792.1 - 0.089 13.0 1.8 1.7 8.9 0.6 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain YL1 PF05764.13 VBB28792.1 - 0.14 12.3 6.4 0.18 11.9 6.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DNA_RNApol_7kD PF03604.13 VBB28792.1 - 0.15 11.8 1.9 0.36 10.6 1.9 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit SDA1 PF05285.12 VBB28792.1 - 0.15 11.4 4.8 0.17 11.3 4.8 1.1 1 0 0 1 1 1 0 SDA1 zf-RING_9 PF13901.6 VBB28792.1 - 0.19 11.7 8.0 0.059 13.3 5.3 1.5 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon DZR PF12773.7 VBB28792.1 - 0.53 10.3 7.5 1.1 9.4 1.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.6 VBB28792.1 - 0.86 10.0 8.7 0.23 11.8 1.5 2.2 2 0 0 2 2 2 0 Ring finger domain zinc-ribbons_6 PF07191.12 VBB28792.1 - 1.6 8.8 7.7 52 3.9 7.7 2.2 1 1 0 1 1 1 0 zinc-ribbons adh_short PF00106.25 VBB28793.1 - 6e-19 68.3 0.1 1.9e-08 34.0 0.0 3.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 VBB28793.1 - 1.4e-07 31.3 0.1 0.018 14.6 0.0 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 VBB28793.1 - 0.00071 19.1 0.1 0.019 14.4 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 VBB28793.1 - 0.0029 17.6 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 VBB28793.1 - 0.049 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 VBB28793.1 - 0.098 12.0 0.0 3.3 7.0 0.0 2.1 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase ANAPC4_WD40 PF12894.7 VBB28795.1 - 0.00028 21.1 0.0 0.3 11.4 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB28795.1 - 0.0009 20.0 0.1 2.2 9.3 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF727 PF05303.12 VBB28796.1 - 4.3e-33 113.5 0.0 7.4e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF727) AAA_6 PF12774.7 VBB28797.1 - 2.2e-127 424.5 0.5 6e-126 419.8 0.0 3.6 4 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 VBB28797.1 - 4.6e-111 372.2 13.7 4.6e-111 372.2 13.7 3.3 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 VBB28797.1 - 4.1e-110 368.6 16.1 4.1e-110 368.6 16.1 5.4 5 2 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 VBB28797.1 - 3.8e-46 156.9 0.1 6.5e-39 133.3 0.0 5.1 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_5 PF07728.14 VBB28797.1 - 4.8e-29 101.1 0.0 1.5e-13 50.9 0.0 5.4 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 VBB28797.1 - 3.2e-17 63.1 0.7 0.00012 22.3 0.0 6.4 6 0 0 6 6 5 3 AAA domain AAA_8 PF12780.7 VBB28797.1 - 6.6e-14 51.8 1.6 4.2e-13 49.2 0.1 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA PF00004.29 VBB28797.1 - 4.2e-13 49.9 0.0 0.0017 18.8 0.0 5.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB28797.1 - 1.3e-12 48.4 0.0 0.052 13.9 0.0 6.0 5 0 0 5 5 4 3 AAA ATPase domain AAA_33 PF13671.6 VBB28797.1 - 2.5e-11 43.9 0.9 0.0034 17.5 0.0 5.8 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 VBB28797.1 - 9.2e-10 39.2 1.5 1.1 9.8 0.0 5.9 5 0 0 5 5 4 3 AAA domain T2SSE PF00437.20 VBB28797.1 - 1.2e-08 34.4 0.2 0.015 14.3 0.0 3.9 4 0 0 4 4 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 VBB28797.1 - 1.6e-08 34.2 0.0 0.027 13.8 0.0 3.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_19 PF13245.6 VBB28797.1 - 1.3e-07 32.0 0.9 0.022 15.1 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 VBB28797.1 - 9.1e-07 28.8 0.6 0.59 9.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 VBB28797.1 - 1.9e-06 27.5 0.4 0.14 11.9 0.0 3.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_28 PF13521.6 VBB28797.1 - 4.5e-06 27.0 0.3 3.7 7.8 0.0 4.9 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 VBB28797.1 - 1.3e-05 24.7 0.1 1.1 8.6 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 VBB28797.1 - 1.6e-05 24.7 0.2 19 4.9 0.0 5.5 5 0 0 5 5 5 0 AAA domain Dynein_AAA_lid PF17852.1 VBB28797.1 - 2e-05 24.7 0.7 0.00011 22.3 0.1 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Rad17 PF03215.15 VBB28797.1 - 9.3e-05 22.4 0.1 4.7 7.1 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_25 PF13481.6 VBB28797.1 - 0.0001 21.9 0.3 0.081 12.5 0.0 4.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 VBB28797.1 - 0.00025 21.0 0.4 3.3 7.6 0.0 4.7 4 0 0 4 4 4 1 RsgA GTPase ABC_tran PF00005.27 VBB28797.1 - 0.00032 21.2 11.0 0.73 10.3 0.0 5.5 6 0 0 6 6 4 1 ABC transporter IstB_IS21 PF01695.17 VBB28797.1 - 0.0005 19.9 0.6 0.19 11.4 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein Pox_A32 PF04665.12 VBB28797.1 - 0.00063 19.3 0.2 5.5 6.4 0.1 3.8 3 0 0 3 3 3 0 Poxvirus A32 protein TsaE PF02367.17 VBB28797.1 - 0.00066 19.7 1.0 4.5 7.3 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 VBB28797.1 - 0.00085 18.7 0.0 5.9 6.1 0.0 4.3 4 0 0 4 4 3 0 Zeta toxin RNA_helicase PF00910.22 VBB28797.1 - 0.0011 19.3 0.1 15 6.1 0.0 4.9 4 0 0 4 4 4 0 RNA helicase AAA_lid_1 PF17857.1 VBB28797.1 - 0.0014 18.8 0.0 0.0062 16.7 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain NACHT PF05729.12 VBB28797.1 - 0.0027 17.7 2.3 22 4.9 0.0 4.7 4 0 0 4 4 3 0 NACHT domain PduV-EutP PF10662.9 VBB28797.1 - 0.009 15.8 0.1 4.7 7.0 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 VBB28797.1 - 0.013 15.4 0.1 38 3.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 VBB28797.1 - 0.014 14.5 2.4 4.8 6.2 0.0 4.5 4 0 0 4 4 4 0 G-protein alpha subunit cobW PF02492.19 VBB28797.1 - 0.019 14.5 1.5 4.3 6.9 0.0 3.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 VBB28797.1 - 0.025 14.3 0.1 1.8 8.3 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 VBB28797.1 - 0.066 13.1 0.2 25 4.7 0.0 3.9 3 0 0 3 3 3 0 NTPase MobB PF03205.14 VBB28797.1 - 0.16 11.9 0.6 20 5.1 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 VBB28797.1 - 0.22 11.6 0.3 99 3.0 0.0 4.5 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 VBB28797.1 - 0.38 10.5 1.3 21 4.7 0.0 3.5 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 VBB28797.1 - 0.41 10.4 0.0 0.41 10.4 0.0 4.2 5 0 0 5 5 4 0 AAA domain Roc PF08477.13 VBB28797.1 - 0.61 10.3 3.3 1e+02 3.1 0.1 5.0 5 0 0 5 5 3 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 VBB28797.1 - 0.76 9.4 7.7 7.8 6.1 0.1 4.9 6 0 0 6 6 5 0 SRP54-type protein, GTPase domain Ku PF02735.16 VBB28798.1 - 1.3e-48 165.5 0.0 2.2e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 VBB28798.1 - 1.8e-25 90.0 3.2 1.8e-25 90.0 3.2 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 VBB28798.1 - 1.5e-15 57.6 2.4 1.9e-15 57.3 0.4 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm HeH PF12949.7 VBB28798.1 - 0.0026 17.4 0.2 0.0065 16.2 0.2 1.6 1 0 0 1 1 1 1 HeH/LEM domain Rho_N PF07498.12 VBB28798.1 - 0.047 13.6 1.6 0.11 12.5 1.6 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Gp-FAR-1 PF05823.12 VBB28799.1 - 1.1e-42 145.9 11.5 1.3e-42 145.6 11.5 1.0 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Syntaxin PF00804.25 VBB28799.1 - 0.00088 19.0 1.4 0.0012 18.5 1.4 1.2 1 0 0 1 1 1 1 Syntaxin Spc7 PF08317.11 VBB28799.1 - 0.0075 15.2 5.1 0.0095 14.8 5.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TEX12 PF15219.6 VBB28799.1 - 0.0085 16.4 0.9 0.023 15.0 0.9 1.7 1 0 0 1 1 1 1 Testis-expressed 12 DUF3106 PF11304.8 VBB28799.1 - 0.012 16.1 1.0 0.13 12.7 0.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) SieB PF14163.6 VBB28799.1 - 0.018 14.5 0.1 0.19 11.2 0.0 2.2 1 1 1 2 2 2 0 Super-infection exclusion protein B DctP PF03480.13 VBB28799.1 - 0.023 14.0 2.0 0.028 13.8 0.7 1.7 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 TAFII28 PF04719.14 VBB28799.1 - 0.064 13.4 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Fzo_mitofusin PF04799.13 VBB28799.1 - 0.095 12.2 0.6 0.35 10.4 0.1 1.9 2 0 0 2 2 2 0 fzo-like conserved region Syntaxin_2 PF14523.6 VBB28799.1 - 0.14 12.5 2.0 0.21 12.0 2.0 1.3 1 0 0 1 1 1 0 Syntaxin-like protein HGD-D PF06050.13 VBB28799.1 - 0.23 11.2 2.2 0.33 10.7 2.2 1.4 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component MRP-L28 PF09812.9 VBB28799.1 - 0.32 11.1 4.3 0.17 12.0 0.7 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 Pet100 PF09803.9 VBB28799.1 - 0.43 11.1 1.9 5.7 7.5 1.9 2.4 1 1 0 1 1 1 0 Pet100 HsbA PF12296.8 VBB28799.1 - 1.3 9.5 4.6 2.5 8.5 2.1 2.5 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Aa_trans PF01490.18 VBB28800.1 - 6.9e-31 107.4 17.5 1.8e-24 86.2 5.5 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein PHO4 PF01384.20 VBB28800.1 - 0.61 9.1 7.2 15 4.5 7.2 2.6 1 1 0 1 1 1 0 Phosphate transporter family Aa_trans PF01490.18 VBB28801.1 - 7.1e-07 28.3 0.2 7.9e-07 28.1 0.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAM_2 PF07647.17 VBB28802.1 - 3e-09 36.9 0.3 5.1e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 VBB28802.1 - 2.7e-05 24.5 0.4 5.1e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RINGv PF12906.7 VBB28803.1 - 3.3e-20 72.0 23.6 3.3e-11 43.1 8.8 3.0 4 0 0 4 4 4 2 RING-variant domain DUF587 PF04532.12 VBB28803.1 - 0.95 8.7 4.6 0.42 9.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF587) MIF4G PF02854.19 VBB28804.1 - 6.4e-35 120.7 10.9 1.3e-34 119.8 10.9 1.5 1 0 0 1 1 1 1 MIF4G domain UPF0524 PF15823.5 VBB28804.1 - 5.8 6.2 9.3 15 4.9 9.3 1.7 1 0 0 1 1 1 0 UPF0524 of C3orf70 Lipase_2 PF01674.18 VBB28805.1 - 2.9e-67 226.4 0.0 3.6e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 2) PI3_PI4_kinase PF00454.27 VBB28807.1 - 3.1e-47 161.5 4.1 3.2e-46 158.2 1.2 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 VBB28807.1 - 5.2e-33 114.0 0.2 1.1e-32 113.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 VBB28807.1 - 4.4e-25 87.2 0.1 1.1e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.24 VBB28807.1 - 5.3e-21 75.0 0.0 1.4e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 VBB28807.1 - 1.2e-12 47.9 0.1 1.7e-11 44.2 0.0 2.6 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain NDUF_B12 PF08122.12 VBB28807.1 - 3.6e-10 39.7 1.9 3.1e-09 36.8 1.5 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF4135 PF13575.6 VBB28807.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) F_actin_cap_B PF01115.17 VBB28808.1 - 4.8e-104 347.2 0.0 7.3e-104 346.6 0.0 1.3 1 0 0 1 1 1 1 F-actin capping protein, beta subunit PAN_1 PF00024.26 VBB28808.1 - 9.7e-08 31.9 7.5 4.2e-05 23.4 0.6 3.5 3 0 0 3 3 3 3 PAN domain Sugar_tr PF00083.24 VBB28809.1 - 6.1e-28 97.9 20.4 1.3e-27 96.8 20.4 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB28809.1 - 1.3e-18 67.1 22.4 7.6e-12 44.8 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiF PF00899.21 VBB28810.1 - 1.4e-102 342.2 0.0 2.4e-70 236.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 VBB28810.1 - 6.5e-87 291.6 6.6 6.5e-87 291.6 6.6 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 VBB28810.1 - 3.4e-29 101.4 2.1 3.4e-29 101.4 2.1 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 VBB28810.1 - 7.2e-26 90.2 0.2 1.5e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 VBB28810.1 - 1.3e-18 66.9 0.3 3.8e-18 65.4 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 VBB28810.1 - 0.0002 21.4 0.4 0.041 13.9 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 VBB28810.1 - 0.00033 20.0 0.0 0.19 11.1 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 VBB28810.1 - 0.077 12.2 0.1 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 VBB28810.1 - 1.5 8.5 5.9 1.4 8.6 0.1 3.1 4 0 0 4 4 4 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.27 VBB28810.1 - 2.6 8.7 7.1 3.9 8.1 0.6 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CPP1-like PF11833.8 VBB28811.1 - 0.005 16.5 8.8 0.005 16.5 8.8 1.4 2 0 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF456 PF04306.13 VBB28811.1 - 0.16 12.3 10.7 0.32 11.3 10.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF456) 7TM_GPCR_Srsx PF10320.9 VBB28811.1 - 0.17 11.2 16.9 0.19 11.1 4.9 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx EMP70 PF02990.16 VBB28811.1 - 0.28 9.8 14.7 0.35 9.5 14.7 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 FUN14 PF04930.15 VBB28811.1 - 1.4 9.4 5.0 18 5.9 0.1 2.5 2 0 0 2 2 2 0 FUN14 family DUF1772 PF08592.11 VBB28811.1 - 1.5 9.1 6.6 0.54 10.6 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) TssN PF17555.2 VBB28811.1 - 3.2 7.1 13.0 4.1 6.7 13.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4131 PF13567.6 VBB28811.1 - 4 7.1 13.1 1.3 8.7 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3290 PF11694.8 VBB28811.1 - 7 6.6 12.8 1.6 8.7 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) Pkinase PF00069.25 VBB28812.1 - 6.9e-66 222.3 0.0 1.1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 VBB28812.1 - 9.7e-52 176.3 0.1 1.7e-51 175.4 0.1 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 VBB28812.1 - 7.4e-44 150.0 0.0 1.1e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB28812.1 - 5.4e-05 22.2 0.0 8.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 VBB28812.1 - 0.00012 21.5 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like UAA PF08449.11 VBB28813.1 - 8.3e-15 54.8 5.5 8.7e-15 54.7 5.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 VBB28813.1 - 0.0003 21.0 10.6 0.00034 20.8 10.6 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 VBB28813.1 - 0.00079 18.9 1.2 0.00079 18.9 1.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PEN-2 PF10251.9 VBB28813.1 - 0.11 12.9 0.6 0.18 12.3 0.2 1.6 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase 7tm_1 PF00001.21 VBB28814.1 - 1.1e-35 123.3 17.3 1.1e-35 123.3 17.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB28814.1 - 4.9e-11 42.5 18.1 4.9e-11 42.5 18.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 VBB28814.1 - 1.3e-07 31.6 20.8 1.3e-07 31.6 20.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2116 PF09889.9 VBB28814.1 - 0.09 12.8 3.7 38 4.4 0.0 4.2 4 0 0 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Herpes_US9 PF06072.11 VBB28814.1 - 5.5 6.9 8.3 1.1 9.2 1.0 3.4 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 LBP_BPI_CETP_C PF02886.17 VBB28815.1 - 4.2e-15 55.9 0.0 6.4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 VBB28815.1 - 0.00014 21.5 0.0 0.00038 20.1 0.0 1.8 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain TSP_1 PF00090.19 VBB28816.1 - 1.8e-77 255.4 181.0 2.1e-10 40.6 8.3 12.5 12 1 0 12 12 12 10 Thrombospondin type 1 domain FAD_binding_4 PF01565.23 VBB28817.1 - 1.1e-08 34.9 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cna_B PF05738.13 VBB28817.1 - 0.06 13.9 0.1 0.098 13.2 0.1 1.3 1 0 0 1 1 1 0 Cna protein B-type domain Ribosomal_L11_N PF03946.14 VBB28818.1 - 4.6e-19 68.0 0.5 3.4e-18 65.2 0.5 2.1 1 1 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 VBB28818.1 - 7e-17 61.7 0.1 1.3e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF2368 PF10166.9 VBB28818.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) CAF1 PF04857.20 VBB28819.1 - 1e-16 61.1 0.0 5.6e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 CAF1 family ribonuclease Peptidase_M50 PF02163.22 VBB28819.1 - 1e-15 57.7 0.7 3.5e-15 55.9 0.7 1.8 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 VBB28819.1 - 0.0041 17.4 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB28819.1 - 0.018 15.4 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 VBB28819.1 - 0.092 12.6 0.0 0.31 10.9 0.0 1.9 3 0 0 3 3 3 0 PDZ domain HECT_2 PF09814.9 VBB28820.1 - 1.1e-21 77.1 0.8 1.1e-21 77.1 0.8 1.4 2 0 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Peptidase_S28 PF05577.12 VBB28821.1 - 1.7e-85 287.4 0.9 1.7e-85 287.4 0.9 1.3 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 VBB28821.1 - 0.0066 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 VBB28821.1 - 0.028 14.1 0.7 0.073 12.7 0.7 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 VBB28821.1 - 0.036 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 VBB28821.1 - 0.062 12.5 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 VBB28821.1 - 0.17 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 VBB28822.1 - 1.1e-108 363.8 0.1 1.5e-108 363.4 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Pkinase_Tyr PF07714.17 VBB28822.1 - 1.9e-20 73.2 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB28822.1 - 3.8e-10 39.6 0.0 6.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peptidase_S9 PF00326.21 VBB28822.1 - 3.1e-05 23.5 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 VBB28822.1 - 0.0014 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 VBB28822.1 - 0.0018 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 VBB28822.1 - 0.045 12.9 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ras PF00071.22 VBB28824.1 - 4.4e-50 169.4 0.0 4.9e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB28824.1 - 2e-19 70.0 0.0 2.7e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB28824.1 - 1.8e-06 27.5 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 VBB28824.1 - 0.014 15.7 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial I-set PF07679.16 VBB28825.1 - 4.4e-13 49.1 0.0 6.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB28825.1 - 9e-13 48.6 0.0 1.5e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 VBB28825.1 - 2e-09 37.5 0.0 3.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 VBB28825.1 - 1.2e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB28825.1 - 0.00071 19.7 0.0 0.011 15.8 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C1-set PF07654.15 VBB28825.1 - 0.0048 17.2 0.0 0.0079 16.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 VBB28825.1 - 0.0077 16.3 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB28825.1 - 0.14 11.7 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain Ribosomal_L17 PF01196.19 VBB28827.1 - 2.9e-07 31.3 0.0 4.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Peptidase_C14 PF00656.22 VBB28828.1 - 7.8e-46 157.0 0.0 1.1e-45 156.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 VBB28828.1 - 2.3e-08 34.0 0.1 6.9e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 Caspase recruitment domain EMG1 PF03587.14 VBB28829.1 - 3e-76 255.4 0.2 3.5e-76 255.2 0.2 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase NTR PF01759.21 VBB28829.1 - 0.027 14.3 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 UNC-6/NTR/C345C module DUF1758 PF05585.12 VBB28830.1 - 8e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF5005 PF16396.5 VBB28830.1 - 0.058 12.1 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) DUF1759 PF03564.15 VBB28831.1 - 2.4e-06 27.5 0.5 0.00059 19.8 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1759) RepA1_leader PF08048.12 VBB28833.1 - 0.081 13.2 0.1 0.081 13.2 0.1 2.0 2 0 0 2 2 2 0 Tap RepA1 leader peptide Sm_multidrug_ex PF06695.11 VBB28833.1 - 0.084 13.5 3.1 3.1 8.5 0.8 2.5 1 1 1 2 2 2 0 Putative small multi-drug export protein RNase_T PF00929.24 VBB28834.1 - 1.6e-17 64.5 0.0 2.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Dimer_Tnp_hAT PF05699.14 VBB28835.1 - 0.0007 19.3 0.1 0.0024 17.6 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region YdfA_immunity PF12127.8 VBB28835.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial UPF0302 PF08864.10 VBB28836.1 - 0.02 14.9 0.5 0.45 10.6 0.2 2.9 2 0 0 2 2 2 0 UPF0302 domain Innexin PF00876.18 VBB28837.1 - 9.3e-97 324.4 10.5 1.2e-96 324.1 10.5 1.1 1 0 0 1 1 1 1 Innexin Ion_trans PF00520.31 VBB28838.1 - 1e-101 339.3 23.3 3.7e-55 186.8 4.4 3.0 2 1 1 3 3 3 3 Ion transport protein PKD_channel PF08016.12 VBB28838.1 - 5.2e-17 61.6 13.8 2.5e-08 33.0 0.0 4.5 4 1 0 4 4 4 4 Polycystin cation channel DUF4834 PF16118.5 VBB28838.1 - 6.4e-05 23.9 2.2 0.33 11.9 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) Connexin PF00029.19 VBB28838.1 - 0.0043 16.8 0.4 2 8.1 0.4 2.5 2 0 0 2 2 2 2 Connexin Phage_Gp23 PF10669.9 VBB28838.1 - 0.023 15.0 0.9 0.29 11.5 1.2 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3139 PF11337.8 VBB28838.1 - 0.12 13.0 0.6 7.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Peptidase_S49_N PF08496.10 VBB28838.1 - 0.55 10.3 3.6 1.4 9.0 2.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ctr PF04145.15 VBB28838.1 - 3.3 8.3 9.6 2 9.0 0.3 3.8 3 2 1 4 4 4 0 Ctr copper transporter family DNA_topoisoIV PF00521.20 VBB28839.1 - 5.9e-125 417.5 0.5 5.9e-125 417.5 0.5 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 VBB28839.1 - 2.3e-48 163.7 6.7 2.3e-48 163.7 6.7 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM Peptidase_S8 PF00082.22 VBB28839.1 - 3.7e-40 138.0 0.1 6.3e-40 137.3 0.1 1.4 1 0 0 1 1 1 1 Subtilase family DNA_gyraseB PF00204.25 VBB28839.1 - 9e-25 87.1 1.6 2e-24 86.0 1.6 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 VBB28839.1 - 3.3e-13 50.1 0.0 1.5e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 VBB28839.1 - 1.6e-07 31.5 0.0 5.6e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.21 VBB28839.1 - 0.021 15.0 0.4 0.068 13.4 0.4 2.0 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus DUF5104 PF17117.5 VBB28839.1 - 0.19 12.2 4.7 11 6.5 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5104) ENT PF03735.14 VBB28839.1 - 0.6 10.2 2.8 1.5 9.0 0.7 2.7 3 0 0 3 3 3 0 ENT domain T6PP_N PF18572.1 VBB28840.1 - 9.9e-26 89.5 2.6 2e-25 88.5 2.6 1.6 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain TssO PF17561.2 VBB28840.1 - 0.098 12.8 3.2 0.26 11.4 3.2 1.7 1 0 0 1 1 1 0 Type VI secretion system, TssO Adaptin_binding PF10199.9 VBB28840.1 - 0.3 11.7 5.0 0.8 10.3 5.0 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spore_III_AB PF09548.10 VBB28840.1 - 1.8 8.6 4.8 9.3 6.3 4.5 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Collagen PF01391.18 VBB28841.1 - 6.5e-25 86.7 92.7 3.7e-10 39.4 29.3 4.1 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28841.1 - 2.9e-07 30.4 0.2 4.3e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB28842.1 - 3e-23 81.4 89.2 2e-10 40.3 27.8 3.6 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28842.1 - 9.7e-08 32.0 0.4 9.7e-08 32.0 0.4 1.5 2 0 0 2 2 2 1 Nematode cuticle collagen N-terminal domain Rapsyn_N PF10579.9 VBB28843.1 - 7.4e-18 64.4 3.9 3.4e-17 62.3 1.8 2.5 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.6 VBB28843.1 - 1.3e-12 47.8 27.7 1.7e-05 25.0 0.1 6.3 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 VBB28843.1 - 2.6e-08 33.3 17.9 0.06 13.4 0.7 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB28843.1 - 0.00015 21.6 15.3 1.9 8.8 0.6 7.1 8 0 0 8 8 6 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 VBB28843.1 - 0.00018 21.7 7.0 0.00018 21.7 7.0 2.4 2 1 0 2 2 1 1 Ring finger domain TPR_1 PF00515.28 VBB28843.1 - 0.00035 20.3 13.8 1.3 8.9 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat zf-RING_11 PF17123.5 VBB28843.1 - 0.0029 17.3 1.2 0.0029 17.3 1.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 VBB28843.1 - 0.0047 17.2 4.6 0.0047 17.2 4.6 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 VBB28843.1 - 0.017 15.4 3.1 0.057 13.7 3.1 1.9 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 VBB28843.1 - 0.035 14.0 9.2 0.086 12.8 9.2 1.7 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 VBB28843.1 - 0.038 13.6 5.7 0.11 12.2 5.7 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 VBB28843.1 - 0.039 13.8 1.1 0.039 13.8 1.1 2.3 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ANAPC5 PF12862.7 VBB28843.1 - 0.085 12.9 2.9 9 6.4 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 VBB28843.1 - 0.1 13.1 1.0 37 5.0 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3H2C3 PF17122.5 VBB28843.1 - 0.34 11.0 6.1 2.7 8.1 6.1 2.5 1 1 0 1 1 1 0 Zinc-finger zf-RING_5 PF14634.6 VBB28843.1 - 3.7 7.6 19.4 0.037 14.0 11.3 2.0 2 0 0 2 2 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 VBB28843.1 - 3.9 7.6 8.7 0.62 10.1 2.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_19 PF14559.6 VBB28843.1 - 4 8.0 11.6 3.1 8.4 0.9 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB28843.1 - 5.9 7.4 13.9 14 6.2 0.2 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat Pkinase PF00069.25 VBB28844.1 - 1.6e-61 208.0 0.1 6.9e-61 205.9 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28844.1 - 3e-34 118.5 0.0 1.4e-33 116.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 VBB28844.1 - 2.8e-18 65.5 0.0 4.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 VBB28844.1 - 9.1e-08 31.7 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB28844.1 - 0.00084 18.8 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 VBB28844.1 - 0.007 16.0 0.8 0.017 14.8 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 VBB28844.1 - 0.027 13.4 0.0 0.06 12.3 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain AMP-binding PF00501.28 VBB28845.1 - 2.6e-92 309.6 0.0 3.7e-62 210.3 0.3 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 VBB28845.1 - 1.1e-15 58.3 0.0 4.7e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain fn3 PF00041.21 VBB28846.1 - 6.9e-28 96.8 10.5 2e-07 31.3 0.1 5.3 5 0 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB28846.1 - 3.6e-10 40.3 2.1 0.42 11.2 0.0 5.1 5 0 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 VBB28846.1 - 8.9e-05 22.8 0.1 3.9 7.9 0.0 3.7 4 0 0 4 4 4 2 Uncharacterised conserved protein (DUF2369) DUF4249 PF14054.6 VBB28846.1 - 0.12 12.0 2.3 2.3 7.8 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4249) Lectin_leg-like PF03388.13 VBB28847.1 - 3.8e-86 288.2 0.1 4.7e-86 287.9 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 VBB28847.1 - 1.2e-10 41.8 2.1 2e-10 41.1 2.1 1.2 1 0 0 1 1 1 1 Bacterial lectin Ldl_recept_a PF00057.18 VBB28848.1 - 1.5e-05 25.1 8.3 0.0024 18.1 0.9 3.1 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A EGF_3 PF12947.7 VBB28848.1 - 2.5 8.4 5.9 1.1 9.6 2.0 2.4 2 0 0 2 2 2 0 EGF domain EGF_MSP1_1 PF12946.7 VBB28848.1 - 5.2 7.2 11.5 1 9.4 3.3 3.1 2 0 0 2 2 2 0 MSP1 EGF domain 1 Peptidase_M20 PF01546.28 VBB28849.1 - 2.5e-34 118.8 0.0 3.3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 VBB28849.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain DLIC PF05783.11 VBB28850.1 - 2.2e-79 267.5 3.9 1.8e-76 257.9 0.6 2.8 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 VBB28850.1 - 0.0086 16.0 0.2 0.75 9.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 VBB28850.1 - 0.009 16.4 0.4 0.059 13.7 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain G-alpha PF00503.20 VBB28850.1 - 0.043 13.0 0.2 1.7 7.7 0.0 2.4 3 0 0 3 3 3 0 G-protein alpha subunit Roc PF08477.13 VBB28850.1 - 0.12 12.6 0.0 0.55 10.5 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 VBB28850.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TUDOR PF00567.24 VBB28851.1 - 9e-15 54.8 0.1 3.6e-09 36.7 0.0 2.9 3 0 0 3 3 3 2 Tudor domain SecA_SW PF07516.13 VBB28851.1 - 0.051 13.6 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 SecA Wing and Scaffold domain EF-G-binding_N PF07299.11 VBB28852.1 - 7.9 7.1 9.0 11 6.6 0.0 4.2 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal Peptidase_C54 PF03416.19 VBB28853.1 - 8.9e-83 277.9 0.0 3.4e-80 269.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase family C54 Tmemb_161AB PF10268.9 VBB28854.1 - 5.3e-59 200.1 20.1 1.4e-57 195.5 16.1 2.1 1 1 1 2 2 2 2 Predicted transmembrane protein 161AB WD40 PF00400.32 VBB28855.1 - 7.8e-12 45.5 4.8 0.019 15.8 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat AAA_assoc_2 PF16193.5 VBB28855.1 - 0.05 13.9 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA C-terminal domain Collagen PF01391.18 VBB28856.1 - 1.2e-23 82.6 118.1 4.1e-09 36.0 44.8 4.1 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28856.1 - 4.5e-21 74.7 1.4 5.5e-21 74.4 1.4 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain FAM176 PF14851.6 VBB28857.1 - 0.00018 21.2 1.2 0.0002 21.1 1.2 1.1 1 0 0 1 1 1 1 FAM176 family DNA_pol_phi PF04931.13 VBB28857.1 - 0.01 14.0 14.0 0.012 13.8 14.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 VBB28857.1 - 0.014 14.6 3.2 0.014 14.7 3.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3169 PF11368.8 VBB28857.1 - 0.051 13.1 0.4 0.061 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MAP17 PF15807.5 VBB28857.1 - 0.11 12.8 0.2 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CPSF100_C PF13299.6 VBB28857.1 - 0.16 12.2 2.1 0.17 12.0 2.1 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RRN3 PF05327.11 VBB28857.1 - 0.42 9.1 6.7 0.39 9.2 6.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PI3K_1B_p101 PF10486.9 VBB28857.1 - 1.4 6.6 4.4 1.4 6.6 4.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 VBB28857.1 - 1.4 7.1 15.3 1.6 6.9 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 VBB28857.1 - 1.7 8.6 9.8 2.1 8.3 9.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 VBB28857.1 - 1.9 7.8 9.9 2.1 7.6 9.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PTPRCAP PF15713.5 VBB28857.1 - 2.2 8.5 11.3 2.8 8.2 11.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 VBB28857.1 - 2.7 7.3 13.7 2.9 7.2 13.7 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 VBB28857.1 - 3 6.0 10.7 3.2 5.9 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 VBB28857.1 - 3.5 7.3 9.6 3.9 7.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 VBB28857.1 - 6.2 6.1 15.9 7.4 5.8 15.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 VBB28857.1 - 7.3 5.6 17.9 8.4 5.4 17.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EBV-NA3 PF05009.12 VBB28857.1 - 9.6 5.7 6.7 12 5.4 6.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF148 PF02520.17 VBB28858.1 - 2.7e-07 30.7 3.3 2.7e-07 30.7 3.3 1.3 2 0 0 2 2 2 1 Domain of unknown function DUF148 rhaM PF05336.13 VBB28858.1 - 0.0031 17.5 0.4 0.0061 16.6 0.4 1.5 1 0 0 1 1 1 1 L-rhamnose mutarotase LPD39 PF18858.1 VBB28858.1 - 0.014 15.5 0.3 0.02 15.0 0.3 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 4HB_MCP_1 PF12729.7 VBB28858.1 - 0.015 14.9 1.4 0.02 14.5 1.4 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction YkyA PF10368.9 VBB28858.1 - 0.09 12.4 5.7 0.15 11.7 5.5 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF148 PF02520.17 VBB28859.1 - 2.1e-10 40.7 11.8 2.1e-10 40.7 11.8 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF148 Lipase_chap PF03280.14 VBB28859.1 - 0.0085 16.1 0.6 0.0085 16.1 0.6 2.9 2 1 1 3 3 3 1 Proteobacterial lipase chaperone protein PCEMA1 PF07418.11 VBB28859.1 - 0.051 13.1 0.9 0.06 12.9 0.9 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 AAA_32 PF13654.6 VBB28859.1 - 0.061 12.1 6.2 0.076 11.8 6.2 1.1 1 0 0 1 1 1 0 AAA domain SAS-6_N PF16531.5 VBB28859.1 - 0.083 13.5 0.7 0.083 13.5 0.7 1.8 2 1 0 2 2 2 0 Centriolar protein SAS N-terminal DUF5061 PF16587.5 VBB28859.1 - 0.088 12.9 1.4 0.14 12.3 0.2 1.9 1 1 1 2 2 2 0 17 kDa common-antigen outer membrane protein DUF1542 PF07564.11 VBB28859.1 - 0.46 10.6 0.1 0.46 10.6 0.1 3.1 2 2 0 2 2 2 0 Domain of Unknown Function (DUF1542) Exonuc_VII_L PF02601.15 VBB28859.1 - 0.95 9.0 9.5 1.2 8.7 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 VBB28859.1 - 2.7 6.8 4.8 5.3 5.8 4.6 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein AA_permease PF00324.21 VBB28860.1 - 1.8e-15 56.5 16.4 1.8e-15 56.5 16.4 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 VBB28860.1 - 8e-07 29.0 4.2 8e-07 29.0 4.2 3.2 2 0 0 2 2 2 1 C-terminus of AA_permease Nepo_coat_N PF03689.15 VBB28860.1 - 0.011 15.7 0.1 0.035 14.1 0.1 2.0 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain DnaB PF00772.21 VBB28860.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Pkinase_Tyr PF07714.17 VBB28861.1 - 1.3e-88 296.7 0.0 1.8e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB28861.1 - 2.5e-38 132.0 0.0 3.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 VBB28861.1 - 3.1e-17 62.6 7.5 9.4e-17 61.1 7.5 1.9 1 0 0 1 1 1 1 Kringle domain Fz PF01392.22 VBB28861.1 - 7.1e-06 26.6 1.5 2.2e-05 25.1 1.5 1.9 1 0 0 1 1 1 1 Fz domain Kinase-like PF14531.6 VBB28861.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Arrestin_N PF00339.29 VBB28862.1 - 3e-17 63.1 0.0 1.1e-16 61.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 VBB28862.1 - 3.6e-14 53.4 0.2 3.4e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Nro1 PF12753.7 VBB28862.1 - 0.039 12.9 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Laminin_EGF PF00053.24 VBB28863.1 - 1.3e-150 489.5 437.2 5.8e-10 39.2 11.9 22.6 21 1 1 22 22 22 22 Laminin EGF domain Laminin_G_2 PF02210.24 VBB28863.1 - 4.5e-107 353.6 3.7 2.8e-24 86.1 0.1 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 VBB28863.1 - 2.3e-96 319.0 0.1 1.9e-22 79.9 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_B PF00052.18 VBB28863.1 - 3.6e-21 75.5 0.0 6.9e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_N PF00055.17 VBB28863.1 - 2.1e-20 73.3 0.5 2.2e-13 50.4 0.1 5.5 5 1 1 6 6 6 2 Laminin N-terminal (Domain VI) Laminin_G_3 PF13385.6 VBB28863.1 - 1.3e-18 67.6 1.3 0.0018 18.5 0.0 4.9 5 1 0 5 5 5 4 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 VBB28863.1 - 3.8e-11 43.1 1.1 3.8e-11 43.1 1.1 5.4 3 1 3 6 6 6 1 Laminin Domain II Aida_N PF08910.10 VBB28863.1 - 0.42 11.0 7.4 1.6 9.1 1.6 3.3 3 0 0 3 3 3 0 Aida N-terminus SesA PF17107.5 VBB28863.1 - 1.8 8.8 10.0 0.023 14.9 0.4 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Laminin_N PF00055.17 VBB28864.1 - 9.2e-20 71.2 0.1 1.2e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) ThiF PF00899.21 VBB28865.1 - 4.4e-31 108.1 0.0 5.7e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2177 PF09945.9 VBB28865.1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) Methyltransf_12 PF08242.12 VBB28865.1 - 0.043 14.6 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 VBB28865.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EGL-1 PF11430.8 VBB28867.1 - 0.022 14.6 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 ELYS-bb PF16687.5 VBB28869.1 - 6.3e-13 48.1 0.3 2.2e-12 46.3 0.3 1.8 1 1 0 1 1 1 1 beta-propeller of ELYS nucleoporin ELYS PF13934.6 VBB28869.1 - 0.00022 21.3 0.0 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore complex assembly DUF2746 PF10874.8 VBB28869.1 - 0.013 15.9 0.0 0.21 12.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) ZYG-11_interact PF05884.12 VBB28870.1 - 7.4e-21 74.8 14.3 9.2e-21 74.5 14.3 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 AAA_lid_1 PF17857.1 VBB28870.1 - 3.3 8.0 7.5 15 5.9 0.1 3.7 3 1 1 4 4 4 0 AAA+ lid domain Metallophos PF00149.28 VBB28871.1 - 3.9e-38 132.0 0.0 5.2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Motile_Sperm PF00635.26 VBB28872.1 - 3.2e-08 33.4 0.0 1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Lentivirus_VIF PF05851.11 VBB28872.1 - 0.053 12.4 0.3 0.12 11.3 0.2 1.6 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Methyltrn_RNA_3 PF02598.17 VBB28873.1 - 3.5e-93 312.2 0.0 5.1e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase PS_Dcarbxylase PF02666.15 VBB28873.1 - 3.8e-53 180.0 0.0 6.2e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase SpoU_methylase PF00588.19 VBB28873.1 - 0.029 14.6 0.0 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 SpoU rRNA Methylase family tRNA-synt_2b PF00587.25 VBB28874.1 - 1.4e-38 132.6 0.0 3.3e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 VBB28874.1 - 1.4e-06 28.5 0.8 1.4e-06 28.5 0.8 2.9 4 0 0 4 4 4 2 Seryl-tRNA synthetase N-terminal domain DUF2457 PF10446.9 VBB28874.1 - 0.018 14.2 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UDPGP PF01704.18 VBB28877.1 - 5.2e-189 628.1 2.5 6.1e-189 627.9 2.5 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase zf-C2H2_2 PF12756.7 VBB28878.1 - 5.2e-26 90.9 5.2 1e-25 90.0 5.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) His_Phos_2 PF00328.22 VBB28880.1 - 1.2e-21 77.5 2.2 2.2e-19 70.1 0.3 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pex14_N PF04695.13 VBB28881.1 - 1.6e-10 41.9 0.0 1.6e-10 41.9 0.0 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4840 PF16128.5 VBB28883.1 - 0.064 13.3 0.6 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4840) Y_phosphatase PF00102.27 VBB28884.1 - 3.9e-25 88.8 0.0 4.4e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB28884.1 - 0.00026 20.8 0.6 0.00038 20.3 0.6 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB28884.1 - 0.0021 18.1 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Methyltransf_PK PF05891.12 VBB28884.1 - 0.0028 17.2 0.2 0.049 13.1 0.1 2.0 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase DUF563 PF04577.14 VBB28884.1 - 0.037 14.2 0.1 0.23 11.6 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF563) PTPlike_phytase PF14566.6 VBB28884.1 - 0.044 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 VBB28884.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain zf-C2H2_4 PF13894.6 VBB28887.1 - 2.2e-07 31.1 28.4 0.1 13.5 2.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-CRD PF17979.1 VBB28887.1 - 2.3e-05 24.5 7.1 0.1 12.7 0.0 3.5 3 0 0 3 3 3 2 Cysteine rich domain with multizinc binding regions zf-C2H2 PF00096.26 VBB28887.1 - 0.00025 21.3 28.9 0.21 12.1 2.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 VBB28887.1 - 0.0021 18.3 16.5 0.0029 17.9 4.4 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) Yippee-Mis18 PF03226.14 VBB28887.1 - 0.14 12.4 8.3 0.063 13.5 2.7 3.0 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_jaz PF12171.8 VBB28888.1 - 1.9e-05 24.8 0.4 0.1 12.9 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 VBB28888.1 - 0.00057 20.1 6.8 0.16 12.3 0.0 3.9 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 VBB28888.1 - 0.0071 16.7 4.6 0.0071 16.7 4.6 2.9 2 2 1 3 3 3 2 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 VBB28888.1 - 0.021 14.0 1.6 0.044 13.0 0.6 2.0 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_4 PF13894.6 VBB28888.1 - 0.57 11.2 22.0 2.1 9.4 1.8 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 VBB28888.1 - 0.66 9.8 3.4 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type FOXP-CC PF16159.5 VBB28888.1 - 0.82 10.4 6.4 24 5.6 0.1 4.3 1 1 3 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 VBB28888.1 - 1 9.8 6.1 32 5.1 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 VBB28888.1 - 3.4 8.3 21.3 0.083 13.4 2.2 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 VBB28888.1 - 6.4 7.5 10.1 1.6 9.4 1.1 3.1 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Metallophos PF00149.28 VBB28889.1 - 2.2e-29 103.4 0.1 3.3e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB28889.1 - 4.7e-05 23.8 0.3 4.7e-05 23.8 0.3 2.5 3 0 0 3 3 3 1 Serine-threonine protein phosphatase N-terminal domain YlqD PF11068.8 VBB28890.1 - 0.046 14.1 0.9 0.066 13.6 0.9 1.2 1 0 0 1 1 1 0 YlqD protein DUF3395 PF11875.8 VBB28891.1 - 7.1e-37 126.7 0.0 1.2e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 VBB28891.1 - 3.4e-19 68.7 1.3 3.4e-19 68.7 1.3 1.8 2 0 0 2 2 2 1 DnaJ domain XTBD PF11952.8 VBB28891.1 - 0.02 14.6 0.4 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD DUF2367 PF10164.9 VBB28892.1 - 0.0048 17.4 11.9 0.0048 17.4 11.9 2.3 1 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) Thi4 PF01946.17 VBB28894.1 - 2.6e-07 30.1 0.0 7.4e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 VBB28894.1 - 4e-07 29.5 0.0 0.00035 19.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 VBB28894.1 - 2.8e-06 27.2 0.3 0.0013 18.4 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 VBB28894.1 - 1.4e-05 25.2 0.0 0.00038 20.6 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 VBB28894.1 - 4.4e-05 22.7 0.1 0.00042 19.5 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 VBB28894.1 - 0.00056 19.2 0.1 0.00084 18.7 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 VBB28894.1 - 0.0012 18.2 0.2 0.0021 17.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 VBB28894.1 - 0.0049 15.6 0.1 0.0085 14.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 VBB28894.1 - 0.0049 17.4 0.3 1.8 9.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 VBB28894.1 - 0.018 14.2 0.1 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 VBB28894.1 - 0.023 14.7 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 VBB28894.1 - 0.028 13.7 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 VBB28894.1 - 0.058 12.2 0.3 0.46 9.3 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase EAP30 PF04157.16 VBB28895.1 - 3.9e-69 232.5 0.7 4.6e-69 232.3 0.7 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Spc42p PF11544.8 VBB28895.1 - 0.13 12.2 0.3 0.33 11.0 0.3 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p T-box PF00907.22 VBB28896.1 - 1.6e-49 168.7 0.5 2.2e-49 168.2 0.1 1.4 2 0 0 2 2 2 1 T-box Glyco_hydro_36C PF16874.5 VBB28896.1 - 0.035 14.6 0.0 0.12 12.9 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain RED_N PF07808.13 VBB28897.1 - 7e-60 202.5 11.7 2.6e-32 112.3 4.0 4.0 2 2 2 4 4 4 2 RED-like protein N-terminal region RED_C PF07807.11 VBB28897.1 - 3.6e-43 146.6 7.3 3.6e-43 146.6 7.3 3.0 4 0 0 4 4 4 1 RED-like protein C-terminal region Ndufs5 PF10200.9 VBB28898.1 - 0.16 12.3 0.3 0.49 10.7 0.3 1.8 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Collagen PF01391.18 VBB28899.1 - 7.9e-26 89.6 93.4 9.1e-05 22.1 7.4 4.4 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB28899.1 - 4.1e-15 55.6 2.0 5.9e-15 55.1 2.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain ATP-sulfurylase PF01747.17 VBB28900.1 - 1.6e-65 220.6 0.0 2.6e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 VBB28900.1 - 2.5e-65 219.2 0.0 4.1e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 VBB28900.1 - 1.4e-37 128.8 0.0 2.8e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain TTR-52 PF01060.23 VBB28900.1 - 2e-11 44.4 0.0 4.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Transthyretin-like family AAA_33 PF13671.6 VBB28900.1 - 6.4e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB28900.1 - 0.0082 16.7 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB28900.1 - 0.0095 16.3 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain PRK PF00485.18 VBB28900.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 VBB28900.1 - 0.24 11.1 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ion_trans PF00520.31 VBB28904.1 - 7.8e-23 81.0 16.6 1.1e-22 80.5 16.6 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 VBB28904.1 - 2.1e-19 69.7 4.1 5.5e-19 68.3 4.1 1.8 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 VBB28904.1 - 5.4e-19 68.1 0.0 8.7e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1664 PF07889.12 VBB28904.1 - 0.077 13.0 3.3 0.79 9.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CRR7 PF12095.8 VBB28904.1 - 0.16 12.5 3.5 0.2 12.1 0.7 2.5 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Ion_trans_2 PF07885.16 VBB28904.1 - 0.37 10.8 5.4 1.4 9.0 5.1 2.3 1 1 0 1 1 1 0 Ion channel KH_10 PF17905.1 VBB28906.1 - 5.9e-36 122.8 0.5 3.1e-35 120.5 0.2 2.5 2 0 0 2 2 2 1 GLD-3 KH domain 5 KH_1 PF00013.29 VBB28906.1 - 4.9e-06 26.3 0.0 0.0027 17.5 0.0 3.2 3 0 0 3 3 3 2 KH domain SWI2_SNF2 PF18766.1 VBB28906.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Mlo PF03094.15 VBB28907.1 - 0.029 12.8 1.0 0.035 12.5 1.0 1.1 1 0 0 1 1 1 0 Mlo family SRP54 PF00448.22 VBB28907.1 - 0.068 12.8 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain 7tm_1 PF00001.21 VBB28909.1 - 4.2e-08 32.8 17.5 1.3e-07 31.3 17.5 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) SNURF PF07192.11 VBB28909.1 - 0.15 11.9 0.6 0.33 10.8 0.1 1.7 2 0 0 2 2 2 0 SNURF/RPN4 protein PfkB PF00294.24 VBB28910.1 - 1.6e-63 214.9 0.3 1.8e-63 214.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 VBB28910.1 - 1.3e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase_C PF02875.21 VBB28910.1 - 0.048 13.9 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain RP-C PF03428.13 VBB28910.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 2 0 0 2 2 2 0 Replication protein C N-terminal domain Unpaired PF15972.5 VBB28910.1 - 0.15 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Unpaired protein ZYG-11_interact PF05884.12 VBB28913.1 - 2.5e-27 96.1 7.8 3e-27 95.8 7.8 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 Ofd1_CTDD PF10637.9 VBB28915.1 - 2e-27 96.2 1.3 1.8e-22 79.9 0.6 3.0 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 VBB28915.1 - 3.1e-26 91.8 0.2 2e-22 79.6 0.0 2.7 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 VBB28915.1 - 3.3e-18 66.4 0.0 3.3e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily OATP PF03137.20 VBB28919.1 - 7.6e-131 437.1 19.4 1.2e-130 436.4 19.4 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 VBB28919.1 - 4.9e-09 35.6 39.9 7.4e-08 31.7 13.4 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 VBB28919.1 - 0.00043 20.3 11.3 0.00043 20.3 11.3 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Yos1 PF08571.10 VBB28919.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Yos1-like Ank_2 PF12796.7 VBB28922.1 - 1e-44 151.0 12.1 5.5e-12 46.1 0.8 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB28922.1 - 2.2e-44 149.3 15.2 2.1e-10 40.9 0.5 7.9 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB28922.1 - 7.4e-27 90.4 18.9 0.0033 17.8 0.0 10.8 10 1 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 VBB28922.1 - 1.6e-24 85.2 22.8 9.7e-06 25.8 0.1 10.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 VBB28922.1 - 1.1e-21 76.6 14.6 0.0003 21.0 0.0 7.3 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Motile_Sperm PF00635.26 VBB28923.1 - 3.4e-13 49.4 0.1 7.2e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF840 PF05801.11 VBB28923.1 - 0.085 12.9 0.1 0.31 11.1 0.1 2.0 1 1 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) UNC-79 PF14776.6 VBB28926.1 - 1.6e-178 594.8 6.7 2.3e-178 594.2 6.7 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 Ribosomal_L16 PF00252.18 VBB28927.1 - 1.3e-18 67.3 0.2 4.2e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e Frag1 PF10277.9 VBB28927.1 - 4.4e-11 42.7 0.2 7.8e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family zf-LYAR PF08790.11 VBB28927.1 - 9.7e-11 41.4 3.6 9.7e-11 41.4 3.6 2.9 4 0 0 4 4 4 1 LYAR-type C2HC zinc finger NPM1-C PF16276.5 VBB28927.1 - 0.015 15.3 0.3 0.056 13.4 0.3 2.0 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain zf-ACC PF17848.1 VBB28927.1 - 0.049 13.7 0.4 0.049 13.7 0.4 3.1 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF4780 PF16012.5 VBB28927.1 - 0.063 12.8 2.5 0.09 12.2 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4780) zf_UBZ PF18439.1 VBB28927.1 - 0.16 11.6 7.0 8.2 6.1 0.1 3.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger GrpE PF01025.19 VBB28928.1 - 1.1e-45 155.2 1.4 1.5e-45 154.8 1.4 1.2 1 0 0 1 1 1 1 GrpE Pox_MCEL PF03291.16 VBB28928.1 - 0.025 13.7 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Metallophos PF00149.28 VBB28929.1 - 3.3e-30 106.1 0.0 4.4e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Dehydratase_MU PF02288.15 VBB28930.1 - 0.015 15.2 0.4 0.036 13.9 0.4 1.6 1 0 0 1 1 1 0 Dehydratase medium subunit ATP-synt_C PF00137.21 VBB28930.1 - 3.4 8.1 6.6 5.8 7.3 6.6 1.3 1 0 0 1 1 1 0 ATP synthase subunit C Neur_chan_LBD PF02931.23 VBB28931.1 - 2.2e-44 151.5 3.0 3.1e-44 151.0 3.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB28931.1 - 5.3e-21 75.8 0.3 9e-21 75.0 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Chorein_N PF12624.7 VBB28934.1 - 3.1e-17 62.8 2.6 1.7e-14 54.0 0.5 3.0 3 0 0 3 3 3 2 N-terminal region of Chorein or VPS13 CdiA_C PF18451.1 VBB28935.1 - 0.0085 16.3 0.2 0.0085 16.3 0.2 2.0 2 0 0 2 2 2 1 Contact-dependent growth inhibition CdiA C-terminal domain Bap31_Bap29_C PF18035.1 VBB28935.1 - 0.071 13.1 1.9 1.2 9.2 0.1 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ribosomal_S5 PF00333.20 VBB28937.1 - 4.2e-24 84.3 0.8 8e-24 83.4 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 VBB28937.1 - 2.4e-16 58.9 0.0 5.1e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Exo_endo_phos PF03372.23 VBB28937.1 - 2.6e-07 30.4 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 VBB28938.1 - 1e-25 90.1 1.0 1.6e-06 28.6 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB28938.1 - 3.5e-24 84.9 2.4 4.8e-06 27.0 0.1 6.1 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 VBB28938.1 - 2e-23 81.7 4.5 8.5e-05 22.8 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Patatin PF01734.22 VBB28938.1 - 3.8e-23 82.8 0.8 1.7e-22 80.6 0.8 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_5 PF13857.6 VBB28938.1 - 3.2e-20 71.9 6.9 6.5e-07 29.5 0.1 5.4 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB28938.1 - 1.1e-16 59.2 4.6 0.0031 17.9 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat EGF PF00008.27 VBB28941.1 - 3.5e-46 155.1 157.5 1.5e-08 34.8 6.6 10.8 10 1 1 11 11 11 9 EGF-like domain hEGF PF12661.7 VBB28941.1 - 2.7e-26 91.2 132.1 1.2e-05 25.7 6.2 12.0 11 1 0 11 11 11 8 Human growth factor-like EGF DSL PF01414.19 VBB28941.1 - 6.3e-17 61.6 2.1 6.3e-17 61.6 2.1 9.0 7 2 3 10 10 10 3 Delta serrate ligand EGF_2 PF07974.13 VBB28941.1 - 4.1e-10 39.9 179.7 0.028 14.8 12.3 11.2 11 0 0 11 11 11 9 EGF-like domain EGF_CA PF07645.15 VBB28941.1 - 9.1e-07 29.0 141.3 0.012 15.8 13.5 10.8 3 3 6 10 10 10 5 Calcium-binding EGF domain EGF_3 PF12947.7 VBB28941.1 - 0.0086 16.2 14.8 0.0086 16.2 14.8 9.8 8 1 1 9 9 9 6 EGF domain Innexin PF00876.18 VBB28942.1 - 2.7e-109 365.7 9.7 2.7e-109 365.7 9.7 2.0 2 0 0 2 2 2 1 Innexin SUFU_C PF12470.8 VBB28942.1 - 3.2 7.7 15.8 0.28 11.2 7.9 2.4 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain TB2_DP1_HVA22 PF03134.19 VBB28944.1 - 0.063 13.2 0.3 0.091 12.7 0.3 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family STAG PF08514.11 VBB28945.1 - 2.8e-29 101.3 0.0 2.7e-28 98.2 0.0 2.8 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.7 VBB28945.1 - 0.004 17.2 2.7 0.0073 16.4 0.1 2.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 VBB28945.1 - 0.1 12.5 4.5 0.96 9.4 0.0 3.6 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Arylesterase PF01731.20 VBB28947.1 - 0.037 14.2 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Acetyltransf_18 PF18014.1 VBB28948.1 - 2e-08 34.1 0.2 2.7e-07 30.5 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Prenylcys_lyase PF07156.14 VBB28949.1 - 1.2e-63 215.4 6.4 5.1e-63 213.4 6.4 1.9 1 1 0 1 1 1 1 Prenylcysteine lyase TPR_1 PF00515.28 VBB28949.1 - 3.1e-23 80.6 15.7 6.1e-06 25.8 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 VBB28949.1 - 1.6e-21 74.6 14.5 0.0021 18.0 0.1 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 VBB28949.1 - 2.4e-19 67.9 8.0 0.0035 17.4 0.0 7.5 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 VBB28949.1 - 6e-14 51.3 15.0 0.0052 17.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB28949.1 - 2.8e-12 46.7 6.4 0.0054 17.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB28949.1 - 1.3e-11 44.3 8.1 0.023 15.5 0.0 6.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB28949.1 - 1.7e-11 44.5 10.6 0.0018 18.7 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat NAD_binding_8 PF13450.6 VBB28949.1 - 3.4e-08 33.6 0.1 8.4e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPR_11 PF13414.6 VBB28949.1 - 5.6e-07 29.1 12.1 0.69 9.6 0.0 6.4 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 VBB28949.1 - 7.2e-07 29.8 10.4 0.29 11.8 0.3 6.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB28949.1 - 1.6e-06 27.7 5.4 0.59 10.3 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB28949.1 - 1.1e-05 25.7 12.7 0.53 11.0 0.2 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB28949.1 - 4.4e-05 22.8 1.5 0.094 11.9 0.7 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB28949.1 - 0.00025 21.2 7.4 0.39 11.0 0.1 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NAD_binding_9 PF13454.6 VBB28949.1 - 0.00026 21.0 0.1 0.16 11.9 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 VBB28949.1 - 0.0014 17.9 0.2 0.071 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPR_9 PF13371.6 VBB28949.1 - 0.0016 18.6 8.1 0.52 10.5 0.3 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB28949.1 - 0.0072 16.2 11.0 0.23 11.4 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DAO PF01266.24 VBB28949.1 - 0.011 15.3 0.3 0.023 14.3 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPR_20 PF14561.6 VBB28949.1 - 0.025 14.9 3.8 5.2 7.5 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 VBB28949.1 - 0.042 13.9 0.0 0.41 10.7 0.0 2.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 VBB28949.1 - 0.044 13.8 2.7 2.3 8.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 VBB28949.1 - 0.14 12.8 6.8 18 6.3 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 VBB28949.1 - 0.23 11.1 1.6 0.83 9.3 0.1 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) MIT PF04212.18 VBB28949.1 - 0.25 11.5 1.4 2.7 8.1 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Asp4 PF16996.5 VBB28951.1 - 0.013 15.2 1.7 0.032 14.0 1.7 1.7 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 DUF3176 PF11374.8 VBB28951.1 - 1 9.6 5.4 0.85 9.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) NS3_envE PF02723.14 VBB28951.1 - 6.2 7.0 9.5 0.78 9.9 2.7 2.2 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E TMEM154 PF15102.6 VBB28951.1 - 8.7 6.3 10.1 12 5.7 5.9 2.1 1 1 1 2 2 2 0 TMEM154 protein family FXa_inhibition PF14670.6 VBB28952.1 - 6.9e-55 183.0 144.2 1.1e-11 44.8 7.5 39.9 13 3 19 32 32 32 9 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 VBB28952.1 - 1.4e-37 127.6 613.0 0.0012 19.0 14.4 34.0 7 6 25 32 32 32 22 Laminin EGF domain EGF_CA PF07645.15 VBB28952.1 - 4.6e-28 97.2 85.0 5.9e-09 36.0 5.5 35.4 23 6 11 34 34 34 8 Calcium-binding EGF domain cEGF PF12662.7 VBB28952.1 - 8.4e-28 95.9 64.1 4.7e-09 36.0 3.5 38.5 38 4 1 39 39 39 11 Complement Clr-like EGF-like hEGF PF12661.7 VBB28952.1 - 5.9e-06 26.7 61.2 0.0013 19.3 5.8 40.7 38 4 3 41 41 41 20 Human growth factor-like EGF EGF_2 PF07974.13 VBB28952.1 - 7e-05 23.1 36.8 0.00089 19.6 13.3 47.5 35 16 7 42 42 42 15 EGF-like domain EGF_3 PF12947.7 VBB28952.1 - 9.8e-05 22.5 6.9 9.8e-05 22.5 6.9 35.4 33 4 1 34 34 34 7 EGF domain EGF PF00008.27 VBB28952.1 - 0.00013 22.1 53.2 0.0011 19.3 7.1 42.1 42 5 0 42 42 42 20 EGF-like domain DSL PF01414.19 VBB28952.1 - 0.0021 18.3 13.8 0.0021 18.3 13.8 30.6 28 5 4 32 32 32 10 Delta serrate ligand Glycos_transf_2 PF00535.26 VBB28953.1 - 1e-33 116.6 0.0 1.7e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB28953.1 - 4.5e-17 62.5 2.2 1.1e-16 61.3 2.2 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 VBB28953.1 - 2e-10 40.6 0.0 5.8e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 VBB28953.1 - 6.4e-10 39.3 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 VBB28953.1 - 2.6e-07 30.2 0.0 6.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase S_locus_glycop PF00954.20 VBB28954.1 - 0.092 13.3 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 S-locus glycoprotein domain EF-hand_1 PF00036.32 VBB28955.1 - 4.4e-14 50.9 11.6 2e-07 30.0 1.8 4.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 VBB28955.1 - 1e-13 51.5 9.3 1.2e-06 28.9 1.5 2.5 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB28955.1 - 7.5e-13 47.3 11.2 1.5e-07 30.7 1.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 VBB28955.1 - 2.3e-09 36.3 6.4 4.9e-05 22.6 2.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 VBB28955.1 - 3.8e-05 23.5 7.9 0.2 11.5 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair UPF0154 PF03672.13 VBB28955.1 - 0.016 15.3 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 VBB28955.1 - 0.024 15.5 0.3 0.096 13.6 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain Syntaxin PF00804.25 VBB28955.1 - 0.052 13.2 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Syntaxin EF-hand_9 PF14658.6 VBB28955.1 - 0.078 13.3 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 VBB28955.1 - 0.1 12.9 0.2 0.92 9.9 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CUE PF02845.16 VBB28955.1 - 0.25 11.1 1.3 0.92 9.3 0.1 2.2 2 0 0 2 2 2 0 CUE domain Gp-FAR-1 PF05823.12 VBB28956.1 - 2e-09 38.0 0.0 2.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BMFP PF04380.13 VBB28956.1 - 0.13 12.8 0.0 6.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity Gp-FAR-1 PF05823.12 VBB28957.1 - 8e-33 113.9 2.3 1.1e-32 113.5 2.3 1.1 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SHMT PF00464.19 VBB28958.1 - 7.2e-193 640.6 0.0 8.5e-193 640.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 VBB28958.1 - 0.0066 15.7 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II CBM_14 PF01607.24 VBB28959.1 - 6.5e-14 51.8 18.5 7e-07 29.3 4.0 2.6 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain WAP PF00095.21 VBB28959.1 - 0.83 10.1 0.1 0.83 10.1 0.1 3.6 4 1 0 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Brr6_like_C_C PF10104.9 VBB28959.1 - 4.2 7.1 5.7 5.3 6.8 0.1 2.9 2 2 1 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Noelin-1 PF12308.8 VBB28960.1 - 0.0053 16.7 4.6 1.2 9.1 1.6 2.3 2 0 0 2 2 2 2 Neurogenesis glycoprotein Pil1 PF13805.6 VBB28960.1 - 0.02 14.4 3.1 0.028 13.9 3.1 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 LXG PF04740.12 VBB28960.1 - 0.047 13.4 0.7 0.077 12.7 0.7 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily CLP1_P PF16575.5 VBB28961.1 - 6.9e-71 237.9 0.0 4e-70 235.4 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 VBB28961.1 - 1.1e-28 99.3 0.1 1.8e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 VBB28961.1 - 8.9e-28 97.1 0.1 1.4e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 TniB PF05621.11 VBB28961.1 - 0.00068 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 VBB28961.1 - 0.0026 17.5 0.0 0.0082 15.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 VBB28961.1 - 0.0046 17.0 0.0 0.013 15.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 VBB28961.1 - 0.011 15.6 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 VBB28961.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 VBB28961.1 - 0.019 14.6 0.2 0.31 10.6 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA PF00004.29 VBB28961.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB28961.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB28961.1 - 0.092 13.1 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Acyl-CoA_dh_1 PF00441.24 VBB28962.1 - 7.8e-39 133.3 0.5 1.3e-38 132.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 VBB28962.1 - 7.6e-23 81.3 0.0 1.2e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 VBB28962.1 - 7e-21 74.2 0.0 1.2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 VBB28962.1 - 2.1e-13 50.7 0.0 4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Neur_chan_LBD PF02931.23 VBB28963.1 - 4.8e-34 117.7 0.9 1.4e-32 113.0 0.9 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB28963.1 - 4.4e-29 102.2 0.6 5.7e-29 101.9 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RPA_interact_N PF14766.6 VBB28964.1 - 5.1e-13 48.4 2.2 9.2e-13 47.6 2.2 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_C PF14768.6 VBB28964.1 - 9e-10 39.0 6.2 2.5e-09 37.5 6.2 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal DUF3135 PF11333.8 VBB28964.1 - 0.031 14.5 0.2 0.077 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) zinc_ribbon_4 PF13717.6 VBB28964.1 - 0.031 14.2 2.4 32 4.6 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 VBB28964.1 - 0.059 13.3 0.1 0.059 13.3 0.1 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS OrfB_Zn_ribbon PF07282.11 VBB28964.1 - 0.091 12.7 1.2 0.34 10.8 0.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RTX_C PF08339.10 VBB28964.1 - 0.13 12.4 0.3 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 RTX C-terminal domain Zn_Tnp_IS1595 PF12760.7 VBB28964.1 - 0.4 10.7 3.7 0.57 10.2 0.3 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Complex1_LYR PF05347.15 VBB28964.1 - 1.8 8.7 7.7 0.28 11.3 0.6 2.6 2 1 0 2 2 2 0 Complex 1 protein (LYR family) Zn-ribbon_8 PF09723.10 VBB28964.1 - 1.9 8.7 6.3 68 3.7 0.5 3.7 3 0 0 3 3 3 0 Zinc ribbon domain Peptidase_M1 PF01433.20 VBB28965.1 - 8.1e-26 90.9 0.2 1.5e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 VBB28965.1 - 1.5e-23 84.0 0.3 4.1e-23 82.5 0.3 1.8 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 VBB28965.1 - 0.0016 18.4 0.0 0.0072 16.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) UPF0697 PF15117.6 VBB28965.1 - 0.0068 16.5 0.1 0.023 14.8 0.1 1.9 1 0 0 1 1 1 1 Uncharacterised protein family UPF0697 ABC2_membrane_3 PF12698.7 VBB28966.1 - 0.6 9.2 6.4 0.67 9.0 6.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RIO1 PF01163.22 VBB28968.1 - 2.7e-42 144.5 0.1 4e-42 144.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 VBB28968.1 - 0.012 15.0 0.2 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 VBB28968.1 - 0.016 14.0 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 VBB28968.1 - 0.026 14.4 0.4 0.06 13.3 0.3 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 VBB28968.1 - 0.064 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH_6_hur PF04655.14 VBB28968.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase RIO1 PF01163.22 VBB28969.1 - 2.5e-11 43.5 0.2 2.5e-11 43.5 0.2 1.8 2 0 0 2 2 2 1 RIO1 family FAD_binding_1 PF00667.20 VBB28970.1 - 6.5e-60 202.5 0.0 9.7e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 VBB28970.1 - 6.5e-32 110.7 0.1 1.4e-31 109.7 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 VBB28970.1 - 1.1e-15 58.3 0.0 4.2e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ribosomal_S21e PF01249.18 VBB28971.1 - 1.5e-34 117.9 0.0 1.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e SH2 PF00017.24 VBB28972.1 - 7.1e-14 51.7 0.0 3.6e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 SH2 domain SH2_2 PF14633.6 VBB28972.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain PTEN_C2 PF10409.9 VBB28973.1 - 2.2e-17 63.1 0.0 3.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 VBB28973.1 - 3.6e-06 26.8 1.2 4.7e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB28973.1 - 1.9e-05 24.4 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB28973.1 - 0.00019 21.5 0.1 0.0004 20.4 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB28973.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate LRAT PF04970.13 VBB28974.1 - 4.8e-26 91.6 0.0 9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Arb2 PF09757.9 VBB28974.1 - 0.0011 18.1 0.2 0.0018 17.4 0.2 1.3 1 0 0 1 1 1 1 Arb2 domain DUF676 PF05057.14 VBB28974.1 - 0.03 13.8 0.1 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Peptidase_C97 PF05903.14 VBB28974.1 - 0.086 12.7 0.4 0.2 11.5 0.4 1.6 1 0 0 1 1 1 0 PPPDE putative peptidase domain SH3_9 PF14604.6 VBB28975.1 - 7.4e-18 64.1 0.2 1.6e-17 63.1 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 VBB28975.1 - 3.4e-13 49.0 0.0 6.3e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB28975.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB28976.1 - 2.9e-24 84.4 0.0 1.6e-11 43.6 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 VBB28976.1 - 7.3e-24 83.4 0.0 1.1e-11 44.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 VBB28976.1 - 1.7e-20 72.4 0.0 2.2e-11 43.3 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain NAD_binding_4 PF07993.12 VBB28978.1 - 2.1e-49 168.0 0.0 2.4e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 VBB28978.1 - 6.8e-08 31.8 1.9 7.3e-07 28.5 1.9 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 VBB28978.1 - 3.1e-07 30.1 0.0 5.9e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 VBB28978.1 - 5.7e-05 22.4 0.2 0.0002 20.6 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 VBB28978.1 - 0.0012 18.0 0.5 0.027 13.6 0.1 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 VBB28978.1 - 0.0042 16.5 0.6 0.019 14.4 0.6 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_transf_54 PF04666.13 VBB28979.1 - 5.8e-93 310.9 1.0 2.7e-82 275.9 0.0 2.2 1 1 1 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Ly49 PF08391.10 VBB28979.1 - 0.011 16.1 0.1 0.027 14.8 0.1 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region UbiA PF01040.18 VBB28980.1 - 5.5e-47 160.2 18.7 7.5e-47 159.7 18.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FKBP_C PF00254.28 VBB28982.1 - 3.3e-32 110.7 0.0 6.2e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HMG_box PF00505.19 VBB28982.1 - 1.5e-11 44.6 13.4 3.1e-07 30.7 0.3 3.3 2 1 1 3 3 3 3 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB28982.1 - 6.9e-09 36.2 11.3 0.00039 21.0 0.1 3.4 2 1 1 3 3 3 3 HMG-box domain DUF3106 PF11304.8 VBB28982.1 - 0.0096 16.4 9.8 1.6 9.3 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3106) Fz PF01392.22 VBB28983.1 - 3e-26 92.2 4.0 3e-26 92.2 4.0 2.3 2 0 0 2 2 2 1 Fz domain ubiquitin PF00240.23 VBB28983.1 - 2.4e-05 24.0 0.0 4.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 VBB28983.1 - 0.00065 19.8 6.5 0.00065 19.8 6.5 2.5 2 0 0 2 2 2 1 AN1-like Zinc finger Ank_2 PF12796.7 VBB28984.1 - 3.7e-08 33.9 0.1 6.1e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB28984.1 - 4.1e-08 32.9 0.0 0.0052 17.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 VBB28984.1 - 6.4e-08 33.0 0.1 1.1e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB28984.1 - 1e-06 28.9 0.4 0.00035 20.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 VBB28984.1 - 1.3e-05 25.4 4.7 0.0008 19.7 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Tcp10_C PF07202.13 VBB28984.1 - 0.0044 17.0 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus GNT-I PF03071.15 VBB28985.1 - 4.2e-113 378.4 0.2 5.6e-113 377.9 0.2 1.1 1 0 0 1 1 1 1 GNT-I family TraS PF10624.9 VBB28985.1 - 0.078 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Pkinase PF00069.25 VBB28986.1 - 1.2e-18 67.5 0.1 1.5e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28986.1 - 7e-09 35.3 0.0 8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB28986.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB28986.1 - 0.002 18.1 0.0 0.2 11.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 VBB28986.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Defensin_beta_2 PF13841.6 VBB28986.1 - 1.1 9.8 9.8 0.11 13.0 2.3 2.8 3 0 0 3 3 3 0 Beta defensin UCH PF00443.29 VBB28987.1 - 2.8e-59 200.7 0.2 4.5e-59 200.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 VBB28987.1 - 6.6e-20 71.5 0.0 1.9e-09 38.0 0.0 3.1 3 0 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 VBB28987.1 - 8e-16 58.5 0.9 6.1e-15 55.6 0.9 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese_C PF12368.8 VBB28987.1 - 2.9 8.3 5.0 27 5.3 0.3 3.0 2 0 0 2 2 2 0 Rhodanase C-terminal Cnd1 PF12717.7 VBB28988.1 - 7.8e-23 81.3 18.0 2.3e-17 63.5 1.2 5.2 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 VBB28988.1 - 1.4e-10 40.5 17.7 0.0084 16.3 0.1 8.3 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 VBB28988.1 - 5.2e-08 33.2 3.1 0.033 14.6 0.1 4.9 4 0 0 4 4 4 2 HEAT repeats Cnd3 PF12719.7 VBB28988.1 - 3.6e-06 26.4 0.6 3.6e-06 26.4 0.6 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 VBB28988.1 - 2.2e-05 24.9 4.1 1.1 9.8 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.20 VBB28988.1 - 0.0096 14.5 18.7 0.02 13.5 0.1 4.4 2 2 2 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.8 VBB28988.1 - 0.026 14.1 1.0 34 3.9 0.1 3.9 2 1 1 3 3 3 0 CLASP N terminal Cohesin_HEAT PF12765.7 VBB28988.1 - 0.048 14.0 0.7 4 7.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion U3snoRNP10 PF12397.8 VBB28988.1 - 3.4 8.0 14.5 0.98 9.8 0.6 4.6 4 2 1 5 5 5 0 U3 small nucleolar RNA-associated protein 10 SNF2_N PF00176.23 VBB28990.1 - 5.4e-62 209.5 2.3 2e-60 204.4 0.8 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB28990.1 - 5.7e-11 42.7 0.1 3.8e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB28990.1 - 5.9e-05 23.1 0.0 0.00023 21.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB28990.1 - 0.0011 18.8 0.0 0.021 14.6 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Hamartin PF04388.12 VBB28991.1 - 1.2e-41 143.2 6.7 1.1e-36 126.8 0.6 3.4 4 0 0 4 4 4 2 Hamartin protein Peptidase_M10 PF00413.24 VBB28991.1 - 3.4e-32 111.5 0.8 6.5e-32 110.6 0.8 1.5 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 VBB28991.1 - 0.0025 17.1 1.4 0.0025 17.1 1.4 2.4 2 0 0 2 2 2 1 Met-zincin Reprolysin_3 PF13582.6 VBB28991.1 - 0.023 15.2 0.6 0.072 13.6 0.6 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MOR2-PAG1_C PF14225.6 VBB28991.1 - 0.032 14.1 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Reprolysin_5 PF13688.6 VBB28991.1 - 0.038 14.1 0.6 0.11 12.7 0.6 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 VBB28991.1 - 0.041 13.5 0.6 0.087 12.5 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4169 PF13770.6 VBB28991.1 - 0.056 13.7 2.1 0.057 13.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Reprolysin_2 PF13574.6 VBB28991.1 - 0.08 12.8 0.7 0.21 11.5 0.7 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 VBB28991.1 - 0.19 11.3 0.8 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Gtr1_RagA PF04670.12 VBB28992.1 - 4.2e-64 216.1 2.2 6.1e-64 215.6 2.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 VBB28992.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 VBB28992.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 VBB28992.1 - 0.00087 18.8 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 VBB28992.1 - 0.02 15.3 0.1 0.21 12.0 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_C11 PF03415.14 VBB28992.1 - 0.036 13.5 0.5 0.051 13.0 0.5 1.2 1 0 0 1 1 1 0 Clostripain family TPR_1 PF00515.28 VBB28992.1 - 0.2 11.5 1.5 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB28992.1 - 0.23 11.7 0.5 0.68 10.3 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 VBB28993.1 - 4.9e-53 180.2 0.1 2e-47 161.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB28993.1 - 1.8e-21 76.6 0.1 8.3e-20 71.2 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 VBB28993.1 - 0.00013 21.0 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB28993.1 - 0.0033 17.4 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 VBB28993.1 - 0.004 16.3 0.1 0.0056 15.8 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 MCM_N PF14551.6 VBB28994.1 - 1.7e-17 63.9 1.6 2.8e-17 63.2 1.6 1.3 1 0 0 1 1 1 1 MCM N-terminal domain MCM_OB PF17207.3 VBB28994.1 - 2.9e-10 40.1 0.2 4.9e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain TetR_C_24 PF17932.1 VBB28994.1 - 0.16 12.2 0.1 0.31 11.3 0.1 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Importin_rep_4 PF18808.1 VBB28995.1 - 9.9e-27 93.1 1.6 1.5e-25 89.3 0.1 3.4 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 VBB28995.1 - 3.2e-18 65.8 0.1 4.6e-12 46.2 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 VBB28995.1 - 6.1e-15 54.1 1.8 0.00018 21.5 0.0 8.2 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 VBB28995.1 - 2.2e-12 47.2 0.0 4.5e-07 30.2 0.0 5.5 5 1 1 6 6 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 VBB28995.1 - 2.6e-09 37.5 0.0 1.5e-06 28.7 0.0 4.8 5 1 0 5 5 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 VBB28995.1 - 8.9e-08 32.3 0.0 0.00016 21.8 0.0 3.5 3 0 0 3 3 2 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 VBB28995.1 - 2.4e-05 23.7 0.3 0.45 9.6 0.1 3.6 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Importin_rep_6 PF18829.1 VBB28995.1 - 0.00067 19.8 0.1 0.00067 19.8 0.1 3.0 3 1 0 3 3 3 1 Importin repeat 6 Adaptin_N PF01602.20 VBB28995.1 - 0.0089 14.6 0.0 0.14 10.7 0.0 2.6 1 1 2 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 VBB28995.1 - 0.031 13.9 0.4 9.1 5.8 0.0 4.3 7 0 0 7 7 7 0 CLASP N terminal IBN_N PF03810.19 VBB28995.1 - 0.057 13.3 0.3 0.26 11.2 0.3 2.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain PMEI PF04043.15 VBB28995.1 - 0.084 13.2 0.1 7.3 6.9 0.0 2.9 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor HEAT_PBS PF03130.16 VBB28995.1 - 0.089 13.5 0.0 62 4.7 0.0 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat ImpA_N PF06812.12 VBB28995.1 - 0.14 12.3 0.1 0.6 10.2 0.1 2.2 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Cys_rich_FGFR PF00839.17 VBB28995.1 - 0.2 11.8 1.6 5.6 7.2 0.0 3.4 3 0 0 3 3 3 0 Cysteine rich repeat GST_C_3 PF14497.6 VBB28996.1 - 1.4e-22 79.7 0.7 2.8e-22 78.8 0.7 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 VBB28996.1 - 3.2e-13 49.7 0.0 5.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 VBB28996.1 - 6.1e-06 26.5 0.6 2.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 VBB28996.1 - 6.4e-05 22.9 0.0 0.00028 20.8 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 VBB28996.1 - 0.0034 17.8 0.0 0.0089 16.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AhpC-TSA PF00578.21 VBB28997.1 - 4e-28 97.8 0.0 5.5e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB28997.1 - 6.2e-12 45.5 0.0 9.3e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 VBB28997.1 - 6.9e-10 38.6 0.1 1.2e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 VBB28997.1 - 0.0021 18.1 0.0 0.031 14.4 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme ISPD_C PF18706.1 VBB28997.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Herpes_V23 PF01802.17 VBB28997.1 - 0.2 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF410 PF04190.13 VBB28998.1 - 1.3e-60 205.3 0.1 1.7e-60 205.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 VBB28998.1 - 0.24 11.6 2.4 1.3 9.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 VBB28999.1 - 2.1e-59 197.3 0.4 4.4e-15 55.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB28999.1 - 4.4e-09 36.3 4.4 1.4 9.1 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif DUF4715 PF15835.5 VBB28999.1 - 0.037 14.1 0.7 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Hep_59 PF07052.11 VBB28999.1 - 0.08 13.7 0.7 0.38 11.5 0.7 2.1 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 FH2 PF02181.23 VBB29000.1 - 7.4e-31 107.6 0.1 8.7e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain MutS_III PF05192.18 VBB29000.1 - 0.078 13.2 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 MutS domain III PH_RBD PF12068.8 VBB29002.1 - 3e-48 163.5 0.0 5e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 VBB29002.1 - 5.9e-35 120.9 8.4 3.3e-34 118.4 3.1 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RUN PF02759.19 VBB29002.1 - 1e-21 77.3 0.3 1.8e-20 73.3 0.0 2.7 3 0 0 3 3 3 1 RUN domain RRN3 PF05327.11 VBB29003.1 - 1.3e-81 274.9 1.1 8.8e-81 272.1 1.1 2.0 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 NFACT-R_1 PF05670.13 VBB29003.1 - 0.099 13.3 0.1 0.19 12.4 0.1 1.4 1 0 0 1 1 1 0 NFACT protein RNA binding domain Hydrolase_like PF13242.6 VBB29004.1 - 1.6e-17 63.3 0.1 4.2e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 VBB29004.1 - 1.8e-14 53.7 0.0 2.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 VBB29004.1 - 1.2e-06 28.8 0.1 7.5e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB29004.1 - 9.6e-06 26.0 0.2 0.0002 21.7 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BLUF PF04940.12 VBB29004.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Sensors of blue-light using FAD RNR_Alpha PF17975.1 VBB29004.1 - 0.085 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain Med20 PF08612.11 VBB29005.1 - 5.8e-19 68.4 0.0 9.4e-19 67.7 0.0 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Sugar_tr PF00083.24 VBB29006.1 - 7.2e-65 219.6 29.2 5.8e-42 144.1 4.6 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 VBB29006.1 - 1.8e-19 69.9 26.3 6.3e-17 61.5 4.6 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily PSI PF01437.25 VBB29006.1 - 1.2 9.8 10.7 0.83 10.2 7.5 2.2 2 0 0 2 2 2 0 Plexin repeat PSI_integrin PF17205.3 VBB29006.1 - 2.7 7.8 11.6 0.66 9.8 6.3 2.4 2 0 0 2 2 2 0 Integrin plexin domain AAA PF00004.29 VBB29007.1 - 4e-38 130.8 0.0 1.4e-37 129.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB29007.1 - 1.3e-11 44.1 0.3 9.3e-11 41.4 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain G-patch PF01585.23 VBB29007.1 - 1.4e-11 44.0 0.0 2.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 G-patch domain RuvB_N PF05496.12 VBB29007.1 - 8.3e-06 25.6 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain zf-CCCH_4 PF18044.1 VBB29007.1 - 2.6e-05 23.9 4.9 5.5e-05 22.9 4.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_5 PF07728.14 VBB29007.1 - 7.4e-05 22.8 0.1 0.00037 20.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) zf_CCCH_4 PF18345.1 VBB29007.1 - 0.0001 22.2 4.2 0.00021 21.2 4.2 1.5 1 0 0 1 1 1 1 Zinc finger domain Vps4_C PF09336.10 VBB29007.1 - 0.00097 19.1 0.3 0.0058 16.6 0.0 2.5 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain zf-CCCH PF00642.24 VBB29007.1 - 0.0016 18.3 2.4 0.003 17.4 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 VBB29007.1 - 0.0026 18.2 3.6 0.0057 17.1 3.6 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger AAA_2 PF07724.14 VBB29007.1 - 0.0038 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 VBB29007.1 - 0.0079 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 VBB29007.1 - 0.014 15.7 0.1 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 VBB29007.1 - 0.026 14.9 2.9 0.038 14.4 0.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 VBB29007.1 - 0.042 14.4 2.1 0.69 10.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 VBB29007.1 - 0.046 13.8 0.1 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 VBB29007.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 VBB29007.1 - 0.079 12.5 0.8 1.7 8.2 0.0 3.0 2 1 0 3 3 3 0 AAA domain DUF4349 PF14257.6 VBB29007.1 - 0.28 10.6 6.8 0.59 9.5 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AAA_22 PF13401.6 VBB29007.1 - 0.3 11.4 11.6 0.24 11.7 1.7 3.9 2 1 0 2 2 2 0 AAA domain CYTL1 PF15153.6 VBB29009.1 - 0.086 12.8 1.6 0.63 10.0 0.2 2.8 2 1 1 3 3 3 0 Cytokine-like protein 1 F-box PF00646.33 VBB29010.1 - 0.013 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain MCM PF00493.23 VBB29011.1 - 2.7e-80 268.7 0.2 5.2e-80 267.7 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 VBB29011.1 - 1.1e-31 109.3 0.1 3e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 VBB29011.1 - 2.8e-23 82.1 3.1 6.6e-23 81.0 3.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 VBB29011.1 - 1.5e-08 35.1 0.0 5.9e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 VBB29011.1 - 2e-07 30.6 0.0 2e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB29011.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 VBB29011.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LST1 PF05083.13 VBB29011.1 - 0.028 14.7 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 LST-1 protein Sigma54_activat PF00158.26 VBB29011.1 - 0.047 13.4 0.0 0.28 10.9 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Integrase_Zn PF02022.19 VBB29011.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain Ribosomal_S8e PF01201.22 VBB29012.1 - 2.9e-52 176.5 0.3 3.5e-52 176.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Collagen PF01391.18 VBB29013.1 - 8.5e-28 95.9 100.4 1.5e-09 37.5 37.2 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB29013.1 - 2.7e-13 49.8 0.0 3.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Steroid_dh PF02544.16 VBB29015.1 - 3.9e-43 147.0 2.7 3.9e-43 147.0 2.7 1.7 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 VBB29015.1 - 4.7e-07 29.6 0.1 6.9e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) BC10 PF06726.12 VBB29015.1 - 3.4 8.0 7.9 2.9 8.2 1.4 3.2 3 0 0 3 3 3 0 Bladder cancer-related protein BC10 Img2 PF05046.14 VBB29017.1 - 4.2e-16 59.0 0.0 7.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) zf-C3HC4_4 PF15227.6 VBB29018.1 - 3.1e-08 33.6 14.2 3.1e-08 33.6 14.2 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 VBB29018.1 - 4.4e-08 33.0 7.5 1.3e-07 31.5 5.9 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB29018.1 - 1.3e-07 31.4 13.6 1.3e-07 31.4 13.6 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB29018.1 - 5.4e-07 29.8 11.7 5.4e-07 29.8 11.7 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB29018.1 - 1.4e-06 28.0 12.3 1.4e-06 28.0 12.3 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB29018.1 - 4.1e-06 26.6 11.7 4.1e-06 26.6 11.7 3.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB29018.1 - 1.3e-05 25.0 10.3 1.3e-05 25.0 10.3 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3613 PF12266.8 VBB29018.1 - 0.031 14.1 0.7 0.056 13.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) zf-rbx1 PF12678.7 VBB29018.1 - 0.038 14.3 7.1 0.038 14.3 7.1 2.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RRPl_C4 PF17026.5 VBB29018.1 - 6.5 6.9 22.0 2.1 8.5 14.1 2.9 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type GTP_EFTU_D3 PF03143.17 VBB29019.1 - 0.077 13.3 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain PCI PF01399.27 VBB29019.1 - 0.1 13.1 1.0 0.31 11.6 0.3 2.1 1 1 1 2 2 2 0 PCI domain HrpB4 PF09502.10 VBB29019.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB4) UCH PF00443.29 VBB29020.1 - 2.7e-40 138.5 0.2 2.7e-40 138.5 0.2 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 VBB29020.1 - 4.3e-14 52.6 0.2 3e-13 49.9 0.5 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 VBB29020.1 - 0.022 14.5 1.0 0.27 11.0 0.7 2.4 2 0 0 2 2 2 0 Variant UBP zinc finger Acyltransferase PF01553.21 VBB29021.1 - 3.9e-20 71.8 0.1 6.2e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 VBB29021.1 - 3.3e-11 43.1 0.1 6.5e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus SK_channel PF03530.14 VBB29022.1 - 4.4e-37 126.6 4.5 8.8e-37 125.6 4.5 1.5 1 0 0 1 1 1 1 Calcium-activated SK potassium channel CaMBD PF02888.16 VBB29022.1 - 8e-29 99.7 3.8 1.9e-28 98.4 3.8 1.7 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 VBB29022.1 - 2.1e-13 50.0 0.1 2.1e-13 50.0 0.1 2.4 2 1 0 2 2 2 1 Ion channel Na_Ca_ex PF01699.24 VBB29022.1 - 0.069 13.1 6.6 0.24 11.3 0.2 2.4 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Ion_trans PF00520.31 VBB29022.1 - 0.078 12.2 9.1 0.24 10.6 6.1 2.2 1 1 1 2 2 2 0 Ion transport protein SUR7 PF06687.12 VBB29022.1 - 5.6 6.5 8.3 3.2 7.3 1.5 2.5 3 0 0 3 3 3 0 SUR7/PalI family Collagen PF01391.18 VBB29024.1 - 2.7e-25 87.9 115.3 0.00037 20.2 19.5 4.1 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB29024.1 - 1.5e-22 79.4 1.7 2.3e-22 78.8 1.7 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain TPR_19 PF14559.6 VBB29025.1 - 2.1e-17 63.4 5.3 0.0011 19.5 0.1 6.0 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29025.1 - 7.5e-16 56.9 15.7 1.5e-06 27.9 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB29025.1 - 1.4e-15 56.4 18.1 1.4e-06 27.8 0.1 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29025.1 - 1.6e-14 53.4 7.6 0.01 16.6 0.0 8.3 4 2 6 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29025.1 - 5e-14 51.6 12.9 0.0069 16.7 0.3 8.4 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB29025.1 - 1e-13 50.3 15.7 3.7e-06 26.7 0.1 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB29025.1 - 8.9e-13 47.7 14.8 2.7e-05 23.7 1.1 8.2 7 2 2 9 9 9 4 TPR repeat TPR_16 PF13432.6 VBB29025.1 - 1.4e-11 44.8 0.3 0.00024 21.7 0.0 4.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29025.1 - 2.3e-09 37.4 3.8 0.0023 18.2 0.2 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB29025.1 - 1.3e-06 28.4 0.8 0.013 15.6 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29025.1 - 1.4e-06 28.4 14.2 0.011 15.9 0.1 6.0 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB29025.1 - 5.9e-06 26.6 9.6 1 10.2 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB29025.1 - 4.2e-05 23.3 2.6 0.011 15.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 VBB29025.1 - 7.9e-05 22.9 3.5 0.75 10.2 0.2 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 VBB29025.1 - 8.5e-05 22.3 0.2 0.00022 21.0 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 VBB29025.1 - 0.0058 17.1 0.1 0.023 15.1 0.0 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 VBB29025.1 - 0.0084 15.3 13.4 0.049 12.8 0.1 4.4 2 1 1 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 VBB29025.1 - 0.047 14.0 0.0 0.59 10.5 0.0 2.7 2 0 0 2 2 2 0 PPR repeat TPR_MalT PF17874.1 VBB29025.1 - 0.072 12.5 0.2 0.072 12.5 0.2 2.0 3 0 0 3 3 2 0 MalT-like TPR region Sel1 PF08238.12 VBB29025.1 - 0.17 12.6 0.1 2.3 9.1 0.0 2.9 2 0 0 2 2 2 0 Sel1 repeat TPR_10 PF13374.6 VBB29025.1 - 0.35 10.8 0.0 0.35 10.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Sterol-sensing PF12349.8 VBB29027.1 - 1.2e-10 41.4 16.3 1.2e-10 41.4 16.3 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 VBB29027.1 - 4.3e-05 21.8 34.0 0.00054 18.2 17.2 2.2 2 0 0 2 2 2 2 Patched family Peptidase_C1 PF00112.23 VBB29028.1 - 4.2e-60 203.6 2.7 4.9e-60 203.3 2.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 VBB29028.1 - 0.028 13.2 0.2 2.9 6.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Beta-lactamase PF00144.24 VBB29029.1 - 2.8e-42 145.1 0.0 9.2e-42 143.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase ANAPC4_WD40 PF12894.7 VBB29031.1 - 1.8e-05 24.9 5.9 0.38 11.1 0.0 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 VBB29031.1 - 0.0018 18.2 25.3 0.076 12.9 0.3 7.4 5 1 1 7 7 7 2 Region in Clathrin and VPS ArAE_1_C PF11728.8 VBB29031.1 - 0.015 15.3 1.7 0.033 14.2 0.3 2.5 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Coatomer_WDAD PF04053.14 VBB29031.1 - 0.031 13.3 21.5 0.06 12.4 0.3 5.3 5 1 1 6 6 6 0 Coatomer WD associated region TPR_7 PF13176.6 VBB29031.1 - 0.17 12.0 8.7 6.8 7.0 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29031.1 - 3.6 8.0 35.1 0.52 10.6 0.3 8.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29031.1 - 4.2 7.7 22.9 2.8 8.3 0.2 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2524 PF10732.9 VBB29031.1 - 4.9 7.5 6.7 21 5.5 0.7 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) PDCD9 PF07147.12 VBB29032.1 - 1.2e-07 31.3 0.5 2.2e-07 30.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Prenyltrans PF00432.21 VBB29033.1 - 6.5e-29 99.4 3.3 2e-07 30.6 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat 4HBT_3 PF13622.6 VBB29034.1 - 5.8e-06 26.7 0.0 8.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 VBB29034.1 - 0.0028 17.5 0.1 0.0045 16.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA thioesterase KH_2 PF07650.17 VBB29035.1 - 2.4e-10 40.1 0.1 2.8e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 KH domain Integrin_alpha2 PF08441.12 VBB29036.1 - 1.6e-76 258.1 0.0 6.1e-75 252.9 0.0 2.2 1 1 1 2 2 2 2 Integrin alpha FG-GAP PF01839.23 VBB29036.1 - 5e-15 55.3 31.1 3.8e-10 39.7 1.7 3.8 4 0 0 4 4 4 3 FG-GAP repeat Integrin_alpha PF00357.20 VBB29036.1 - 8.6e-05 22.2 0.4 0.00024 20.9 0.4 1.8 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region VCBS PF13517.6 VBB29036.1 - 0.00015 22.3 8.9 0.051 14.2 1.5 3.5 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Peptidase_S8 PF00082.22 VBB29037.1 - 1.5e-37 129.5 1.1 2.2e-37 129.0 1.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 VBB29037.1 - 2e-23 82.2 0.1 4.3e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 VBB29037.1 - 1.8e-18 67.0 0.4 3.6e-18 66.1 0.4 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain DNA_pol_B PF00136.21 VBB29038.1 - 2.3e-110 369.4 9.5 2.3e-110 369.4 9.5 1.9 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 VBB29038.1 - 8.4e-26 90.9 0.2 2.2e-25 89.5 0.2 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 VBB29038.1 - 4e-25 88.6 6.7 4e-25 88.6 6.7 3.1 3 0 0 3 3 3 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 VBB29038.1 - 6.1e-20 71.1 5.0 2.4e-19 69.1 5.0 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal eIF-6 PF01912.18 VBB29039.1 - 2.7e-74 248.9 1.9 4.1e-74 248.3 1.9 1.3 1 0 0 1 1 1 1 eIF-6 family Diphthami_syn_2 PF01902.17 VBB29040.1 - 4.2e-45 153.9 0.0 6.3e-45 153.3 0.0 1.2 1 1 0 1 1 1 1 Diphthamide synthase CLTH PF10607.9 VBB29040.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain ThiI PF02568.14 VBB29040.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) BRCT PF00533.26 VBB29041.1 - 2.2e-42 143.3 17.2 2.3e-09 37.5 0.0 6.9 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 VBB29041.1 - 3.2e-40 135.9 15.6 1.4e-15 57.0 0.1 5.8 5 2 0 5 5 5 4 twin BRCT domain BRCT_2 PF16589.5 VBB29041.1 - 4.4e-35 120.0 11.2 4.3e-06 27.0 0.1 6.8 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 VBB29041.1 - 4.9e-15 55.2 3.7 5.2e-07 29.5 0.0 5.4 5 0 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 VBB29041.1 - 1.4e-09 38.1 11.7 0.046 14.0 0.0 6.4 6 0 0 6 6 6 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 VBB29041.1 - 2e-09 37.4 9.0 0.0021 18.1 0.1 6.4 5 1 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain DUF1358 PF07096.11 VBB29042.1 - 0.00031 20.7 0.1 0.00046 20.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) DUF5496 PF17600.2 VBB29042.1 - 0.08 13.0 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5496) DUF3533 PF12051.8 VBB29042.1 - 0.093 11.6 3.3 2.2 7.1 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3533) DUF4199 PF13858.6 VBB29042.1 - 0.18 12.2 1.5 0.23 11.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PIG-L PF02585.17 VBB29043.1 - 7.5e-21 75.1 0.0 1.1e-20 74.7 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Inhibitor_I29 PF08246.12 VBB29044.1 - 2.3e-07 31.1 0.2 2.8e-07 30.9 0.2 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) SIX1_SD PF16878.5 VBB29045.1 - 1.5e-35 122.1 3.0 1.8e-35 121.8 3.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Glyco_hydro_35 PF01301.19 VBB29046.1 - 2.9e-111 372.1 0.7 3.8e-111 371.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 VBB29046.1 - 2.6e-08 33.6 0.3 1.8e-06 27.6 0.0 2.6 2 1 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 VBB29046.1 - 2.3e-07 31.4 0.2 6.2e-07 30.0 0.2 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain ALMT PF11744.8 VBB29047.1 - 3.5 6.4 6.7 4.9 5.9 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DOMON PF03351.17 VBB29048.1 - 1.3e-98 325.8 14.7 4.4e-29 101.2 0.2 5.7 5 0 0 5 5 5 5 DOMON domain TIL PF01826.17 VBB29048.1 - 8.2e-17 61.2 62.5 3.6e-08 33.5 14.6 6.3 5 1 0 5 5 5 3 Trypsin Inhibitor like cysteine rich domain SEA PF01390.20 VBB29048.1 - 4.1e-07 30.0 0.1 1.9e-06 27.9 0.1 2.2 1 0 0 1 1 1 1 SEA domain CDH-cyt PF16010.5 VBB29048.1 - 2.3e-05 24.2 0.0 0.085 12.5 0.0 3.8 3 0 0 3 3 3 2 Cytochrome domain of cellobiose dehydrogenase EGF_2 PF07974.13 VBB29048.1 - 0.0015 18.9 8.3 0.0015 18.9 8.3 5.8 5 0 0 5 5 5 2 EGF-like domain GPI-anchored PF10342.9 VBB29048.1 - 0.009 16.7 2.6 0.063 14.0 0.1 2.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ZYG-11_interact PF05884.12 VBB29049.1 - 7.3e-12 45.3 7.5 1e-11 44.8 7.5 1.1 1 0 0 1 1 1 1 Interactor of ZYG-11 Ni_hydr_CYTB PF01292.20 VBB29049.1 - 0.063 12.9 1.4 0.11 12.1 1.4 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Peptidase_C12 PF01088.21 VBB29050.1 - 1.1e-67 227.9 0.0 3.5e-67 226.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 VBB29050.1 - 1.9e-18 66.1 1.7 1.9e-18 66.1 1.7 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Acetyltransf_6 PF13480.7 VBB29050.1 - 0.16 12.1 0.1 1.5 8.9 0.1 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PRP38 PF03371.15 VBB29051.1 - 3.3e-53 180.1 0.0 4.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Gal-bind_lectin PF00337.22 VBB29052.1 - 1.4e-63 212.4 0.1 3e-32 111.0 0.1 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin Alginate_lyase2 PF08787.11 VBB29052.1 - 8e-05 22.6 1.3 0.0052 16.7 0.6 2.1 1 1 1 2 2 2 2 Alginate lyase Ras PF00071.22 VBB29054.1 - 9.5e-55 184.6 0.1 6.9e-30 103.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 VBB29054.1 - 2.7e-27 95.3 0.1 2.6e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB29054.1 - 2.4e-07 30.4 0.0 0.00035 20.1 0.0 2.3 1 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB29054.1 - 0.00021 21.4 0.0 0.00042 20.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB29054.1 - 0.0018 18.2 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 VBB29054.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Septin Gtr1_RagA PF04670.12 VBB29054.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 VBB29054.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain NOA36 PF06524.12 VBB29055.1 - 2.2 7.5 18.7 3.7 6.8 18.7 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 VBB29056.1 - 2.7e-64 217.1 1.5 5.5e-64 216.1 0.0 2.4 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29056.1 - 3.5e-51 174.0 0.0 1.1e-50 172.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PKK PF12474.8 VBB29056.1 - 5e-51 172.5 74.3 4.9e-29 101.2 28.7 5.3 4 1 1 5 5 5 2 Polo kinase kinase LRRFIP PF09738.9 VBB29057.1 - 4.8e-51 174.0 50.9 1.5e-50 172.3 38.0 3.0 2 1 0 2 2 2 1 LRRFIP family ATG16 PF08614.11 VBB29057.1 - 1.3e-05 25.5 16.7 1.3e-05 25.5 16.7 3.5 2 1 0 3 3 3 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 VBB29057.1 - 0.017 15.6 7.8 0.017 15.6 7.8 3.7 1 1 1 2 2 2 0 Fez1 Cnn_1N PF07989.11 VBB29057.1 - 0.017 15.2 6.0 0.017 15.2 6.0 6.0 3 2 3 6 6 6 0 Centrosomin N-terminal motif 1 Sec8_exocyst PF04048.14 VBB29057.1 - 0.063 13.2 0.5 0.063 13.2 0.5 3.7 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Phage_tail_T PF06223.12 VBB29057.1 - 0.068 13.7 1.5 0.14 12.7 0.9 1.8 1 1 1 2 2 2 0 Minor tail protein T DUF1664 PF07889.12 VBB29057.1 - 0.14 12.2 21.9 0.28 11.2 1.7 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 VBB29057.1 - 0.55 9.1 37.6 0.37 9.6 17.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF745 PF05335.13 VBB29057.1 - 2.6 7.7 39.8 0.65 9.7 13.8 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF745) KASH_CCD PF14662.6 VBB29057.1 - 3.8 7.3 40.3 0.045 13.6 9.2 4.3 2 2 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Piezo_RRas_bdg PF12166.8 VBB29059.1 - 1.9e-19 70.3 1.0 2.1e-19 70.1 1.0 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain SAS-6_N PF16531.5 VBB29060.1 - 0.033 14.7 2.2 0.082 13.5 0.9 2.5 1 1 1 2 2 2 0 Centriolar protein SAS N-terminal DUF4913 PF16259.5 VBB29060.1 - 0.11 12.6 0.2 0.49 10.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4913) Vac_Fusion PF02346.16 VBB29060.1 - 0.15 11.7 7.8 14 5.4 0.0 4.6 4 1 1 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 PMC2NT PF08066.12 VBB29060.1 - 7.1 7.4 7.4 1.4 9.6 0.5 3.0 3 1 1 4 4 4 0 PMC2NT (NUC016) domain adh_short PF00106.25 VBB29062.1 - 6.7e-40 136.6 0.4 9.4e-40 136.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB29062.1 - 1.2e-16 61.0 0.1 1.7e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB29062.1 - 3.3e-05 23.9 0.1 0.00019 21.4 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 VBB29062.1 - 0.0068 15.9 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phage_T4_gp19 PF06841.12 VBB29062.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 SRF-TF PF00319.18 VBB29062.1 - 0.24 10.9 1.6 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) PglL_A PF15864.5 VBB29062.1 - 2.1 8.1 4.9 4.8 7.0 4.9 1.6 1 0 0 1 1 1 0 Protein glycosylation ligase Proteasom_Rpn13 PF04683.13 VBB29063.1 - 1.3e-28 99.4 0.1 2.2e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 VBB29063.1 - 9.3e-22 77.3 0.0 2.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 UCH-binding domain DUF4507 PF14964.6 VBB29064.1 - 1.1e-24 87.1 0.1 1.5e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) RdDM_RDM1 PF09187.10 VBB29064.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 OB_NTP_bind PF07717.16 VBB29066.1 - 6.5e-17 61.7 0.1 9.9e-16 57.9 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold LRR_4 PF12799.7 VBB29066.1 - 0.0019 18.6 3.5 0.068 13.6 0.1 3.5 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box_5 PF18511.1 VBB29066.1 - 0.017 14.7 0.0 0.049 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 VBB29066.1 - 0.1 12.5 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 VBB29066.1 - 0.13 12.3 0.7 4.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat zf-C2H2_4 PF13894.6 VBB29067.1 - 1.1e-19 69.4 49.9 0.004 17.9 1.1 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB29067.1 - 2.7e-18 65.3 60.6 0.0016 18.8 0.1 7.7 8 0 0 8 8 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 VBB29067.1 - 9.3e-08 31.9 39.6 0.066 13.2 2.0 7.1 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB29067.1 - 9.9e-08 32.1 26.0 0.022 15.1 0.0 6.0 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 VBB29067.1 - 3.3e-06 27.3 40.5 0.0091 16.4 0.0 8.6 9 0 0 9 9 8 3 Zinc-finger double domain zf-met PF12874.7 VBB29067.1 - 3.1e-05 24.2 22.0 0.0039 17.5 0.1 5.3 6 0 0 6 6 4 3 Zinc-finger of C2H2 type zf-C2H2_12 PF18658.1 VBB29067.1 - 0.0077 15.8 9.6 1.6 8.3 0.4 4.2 3 1 0 3 3 3 2 Zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 VBB29067.1 - 0.012 16.2 1.7 0.012 16.2 1.7 5.8 3 2 4 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 VBB29067.1 - 0.026 14.3 25.4 0.14 11.9 1.5 5.6 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2HE PF16278.5 VBB29067.1 - 0.07 13.6 0.4 0.07 13.6 0.4 6.6 4 2 0 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 VBB29067.1 - 0.12 12.1 20.7 0.13 11.9 2.6 5.4 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 VBB29067.1 - 0.2 12.0 24.4 0.94 9.8 2.3 5.0 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 VBB29067.1 - 0.39 10.9 23.3 0.61 10.2 0.9 6.0 5 1 0 5 5 5 0 Zinc ribbon domain Ta0938 PF11494.8 VBB29067.1 - 0.44 10.9 10.5 4.1 7.7 0.2 4.8 2 2 3 5 5 5 0 Ta0938 FOXP-CC PF16159.5 VBB29067.1 - 0.7 10.6 9.9 42 4.9 0.1 5.1 4 1 0 4 4 4 0 FOXP coiled-coil domain zf-AD PF07776.15 VBB29067.1 - 2.2 8.6 21.4 0.56 10.5 0.5 4.9 3 1 2 5 5 5 0 Zinc-finger associated domain (zf-AD) HNH_5 PF14279.6 VBB29067.1 - 3.4 7.6 20.5 2.2 8.2 0.4 6.1 5 1 1 6 6 6 0 HNH endonuclease Nipped-B_C PF12830.7 VBB29068.1 - 3.1e-57 193.6 0.0 3.1e-57 193.6 0.0 5.5 6 0 0 6 6 6 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 VBB29068.1 - 1.6e-12 47.5 0.8 1.4e-11 44.5 0.1 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 VBB29068.1 - 1.8e-07 31.3 1.4 0.003 17.6 0.8 4.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 VBB29068.1 - 0.00099 19.2 2.1 2.2 8.8 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 VBB29068.1 - 0.001 19.4 0.4 0.031 14.6 0.0 4.9 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 VBB29068.1 - 0.0025 18.3 0.2 4.6 7.9 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat Dynactin PF12455.8 VBB29069.1 - 3e-32 112.0 0.2 3e-32 112.0 0.2 3.6 2 2 1 4 4 4 1 Dynein associated protein TrbI_Ftype PF09677.10 VBB29069.1 - 0.3 11.4 1.9 4 7.8 0.2 2.9 3 0 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF4201 PF13870.6 VBB29069.1 - 2.2 8.0 65.2 0.12 12.1 17.3 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 VBB29069.1 - 7 6.7 75.9 5.6 7.0 13.0 4.8 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GST_N_4 PF17172.4 VBB29069.1 - 8.2 7.3 10.1 0.37 11.6 0.6 3.4 4 0 0 4 4 4 0 Glutathione S-transferase N-terminal domain GSHPx PF00255.19 VBB29070.1 - 1.8e-40 136.8 1.8 2.6e-40 136.3 0.2 2.1 3 0 0 3 3 3 1 Glutathione peroxidase AhpC-TSA PF00578.21 VBB29070.1 - 0.0002 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB29070.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Redoxin DnaB_C PF03796.15 VBB29071.1 - 5.2e-15 55.5 0.1 3.2e-14 52.9 0.0 2.4 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 VBB29071.1 - 5.5e-14 52.2 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 VBB29071.1 - 1e-06 28.3 0.4 2.6e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 KaiC AAA_22 PF13401.6 VBB29071.1 - 0.0037 17.5 1.1 0.015 15.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 VBB29071.1 - 0.017 14.2 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 VBB29071.1 - 0.035 13.8 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 VBB29071.1 - 0.045 14.3 0.0 0.045 14.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 VBB29071.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 VBB29071.1 - 0.059 13.4 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zn_Tnp_IS91 PF14319.6 VBB29071.1 - 0.12 12.4 0.5 0.32 11.1 0.5 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain tRNA_int_endo PF01974.17 VBB29072.1 - 2.9e-22 78.5 0.0 7.4e-21 74.0 0.0 2.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain LSM PF01423.22 VBB29072.1 - 1.6e-15 56.5 0.1 3.1e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 VBB29072.1 - 0.02 15.0 0.0 0.056 13.6 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain RNB PF00773.19 VBB29073.1 - 1.1e-102 343.7 0.0 1.6e-102 343.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 VBB29073.1 - 2e-23 82.2 0.0 6.7e-23 80.5 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 VBB29073.1 - 2e-21 76.1 0.0 3.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 VBB29073.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 VBB29073.1 - 0.0017 18.5 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 VBB29073.1 - 0.016 14.9 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain AbbA_antirepres PF14156.6 VBB29073.1 - 0.2 11.6 0.6 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Antirepressor AbbA CSD PF00313.22 VBB29074.1 - 8.5e-15 54.4 0.0 1.9e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Spond_N PF06468.13 VBB29075.1 - 2.3e-67 226.9 0.1 3.5e-67 226.3 0.1 1.3 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 VBB29075.1 - 5e-50 167.5 52.0 3.9e-11 43.0 5.0 6.1 5 0 0 5 5 5 5 Thrombospondin type 1 domain Kunitz_BPTI PF00014.23 VBB29075.1 - 6.2e-18 64.8 8.8 6.2e-18 64.8 8.8 2.7 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Reeler PF02014.16 VBB29075.1 - 3.1e-17 63.5 0.0 7.1e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Reeler domain PAP2 PF01569.21 VBB29076.1 - 5.9e-25 87.6 2.3 7.9e-25 87.2 2.3 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 VBB29076.1 - 0.00014 22.3 3.4 0.00014 22.3 3.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily C-terminal UPF0154 PF03672.13 VBB29076.1 - 0.076 13.1 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PAP2_3 PF14378.6 VBB29076.1 - 0.15 11.7 9.4 0.97 9.1 9.3 2.1 1 1 0 1 1 1 0 PAP2 superfamily PAP2 PF01569.21 VBB29078.1 - 2.6e-22 79.1 6.3 1.9e-21 76.2 6.3 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 VBB29078.1 - 0.0039 17.7 2.1 0.0039 17.7 2.1 2.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal LrgB PF04172.16 VBB29078.1 - 0.03 13.8 3.1 0.32 10.5 0.1 2.5 1 1 1 2 2 2 0 LrgB-like family Tmpp129 PF10272.9 VBB29078.1 - 0.16 11.2 0.3 0.29 10.4 0.3 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor PAP2_3 PF14378.6 VBB29078.1 - 3.8 7.2 10.7 1 9.0 5.6 2.4 2 1 0 2 2 2 0 PAP2 superfamily DUF2976 PF11190.8 VBB29078.1 - 9.5 6.1 6.1 0.94 9.3 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Ion_trans_2 PF07885.16 VBB29079.1 - 2e-36 123.8 27.9 6.8e-20 70.8 4.0 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB29079.1 - 1.6e-08 34.1 7.4 0.00023 20.5 2.1 2.4 2 0 0 2 2 2 2 Ion transport protein YlaC PF10777.9 VBB29079.1 - 0.03 14.2 0.4 0.03 14.2 0.4 2.9 3 0 0 3 3 3 0 Inner membrane protein YlaC Rootletin PF15035.6 VBB29079.1 - 0.037 14.1 18.6 0.23 11.5 10.3 2.6 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Adap_comp_sub PF00928.21 VBB29080.1 - 9.3e-25 87.5 0.3 1.7e-24 86.6 0.3 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 VBB29080.1 - 9.4e-05 22.4 0.1 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hat1_N PF10394.9 VBB29081.1 - 1.3e-13 51.5 0.1 3.8e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 VBB29081.1 - 0.0023 18.2 0.0 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB29081.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SPDY PF03771.16 VBB29081.1 - 0.2 11.6 0.2 0.52 10.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) EF-hand_7 PF13499.6 VBB29083.1 - 1.1e-25 89.9 8.1 7.7e-14 51.9 1.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB29083.1 - 3.5e-25 85.6 11.9 7.9e-08 31.3 0.7 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 VBB29083.1 - 4.2e-22 76.1 13.7 2.9e-07 29.9 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 VBB29083.1 - 5e-16 58.3 9.5 1.1e-07 31.6 1.3 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 VBB29083.1 - 4.6e-14 52.5 0.1 1.6e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 VBB29083.1 - 1e-08 34.3 17.0 4.5e-05 22.7 0.3 5.4 3 1 2 5 5 5 2 EF hand EF-hand_4 PF12763.7 VBB29083.1 - 4.1e-05 23.5 2.2 0.0012 18.8 0.1 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Ribosomal_S16 PF00886.19 VBB29083.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S16 Sigma54_CBD PF04963.13 VBB29083.1 - 0.019 14.8 0.4 0.58 10.0 0.1 2.3 1 1 0 2 2 2 0 Sigma-54 factor, core binding domain PHB_acc_N PF07879.11 VBB29083.1 - 0.033 14.3 0.0 0.71 10.0 0.0 2.8 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain Caleosin PF05042.13 VBB29083.1 - 0.37 10.7 3.7 72 3.3 0.1 3.6 1 1 3 4 4 4 0 Caleosin related protein Kazal_2 PF07648.15 VBB29084.1 - 1.9e-63 210.4 139.4 6.3e-10 39.0 4.2 11.4 11 1 0 11 11 11 9 Kazal-type serine protease inhibitor domain Laminin_G_1 PF00054.23 VBB29084.1 - 1.2e-42 145.3 0.0 5.4e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 VBB29084.1 - 9.1e-42 142.6 0.0 9e-17 61.8 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Kazal_1 PF00050.21 VBB29084.1 - 6.7e-39 131.7 125.5 9.7e-08 31.9 9.0 10.1 9 0 0 9 9 9 9 Kazal-type serine protease inhibitor domain Laminin_EGF PF00053.24 VBB29084.1 - 6.4e-11 42.2 33.9 2.2e-09 37.3 10.1 10.7 8 2 0 8 8 8 2 Laminin EGF domain Laminin_G_3 PF13385.6 VBB29084.1 - 0.0067 16.6 0.1 0.052 13.7 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 VBB29084.1 - 0.0094 16.2 2.4 0.0094 16.2 2.4 13.4 14 1 0 14 14 14 1 EGF-like domain bZIP_1 PF00170.21 VBB29085.1 - 7.8e-07 29.1 20.5 1.2e-06 28.6 20.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 VBB29085.1 - 5.2e-06 26.9 11.8 9e-06 26.1 11.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 VBB29085.1 - 9.6e-06 25.6 18.9 8.4e-05 22.6 17.9 2.2 1 1 1 2 2 2 1 Basic region leucine zipper DUF4065 PF13274.6 VBB29085.1 - 0.017 16.0 0.4 0.033 15.1 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) GTSE1_N PF15259.6 VBB29085.1 - 0.031 14.5 3.1 0.038 14.2 3.1 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 FapA PF03961.13 VBB29085.1 - 0.16 10.6 4.1 0.17 10.5 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAM199X PF15814.5 VBB29085.1 - 0.17 10.9 5.0 0.22 10.5 5.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X Phlebovirus_NSM PF07246.11 VBB29085.1 - 0.24 10.7 4.2 0.34 10.2 4.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF724 PF05266.14 VBB29085.1 - 0.35 10.7 8.6 0.2 11.4 5.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 VBB29085.1 - 0.96 9.9 7.7 1.4 9.4 0.5 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2564 PF10819.8 VBB29085.1 - 1.1 9.6 5.6 0.31 11.4 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) 5_nucleotid PF05761.14 VBB29085.1 - 1.6 7.5 5.1 2.5 6.9 5.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family PB1 PF00564.24 VBB29087.1 - 4.6e-12 45.7 0.0 8.1e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 VBB29087.1 - 1.4e-10 41.4 0.2 2.6e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB29087.1 - 6.1e-08 32.4 0.2 1.4e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB29087.1 - 0.082 13.2 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Glycos_transf_2 PF00535.26 VBB29089.1 - 9.4e-37 126.4 0.0 1.3e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 VBB29089.1 - 1.2e-15 58.1 0.0 1.6e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Mitoc_L55 PF09776.9 VBB29089.1 - 2.8e-11 43.2 0.0 4.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 Glyco_transf_21 PF13506.6 VBB29089.1 - 2e-06 27.4 0.0 7.7e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 VBB29089.1 - 2.1e-06 27.4 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 VBB29089.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 VBB29089.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_7N PF13733.6 VBB29089.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DBC1 PF14443.6 VBB29090.1 - 1e-34 119.2 0.1 6.2e-34 116.7 0.0 2.4 2 0 0 2 2 2 1 DBC1 S1-like PF14444.6 VBB29090.1 - 2.1e-30 104.4 0.2 4.8e-30 103.3 0.2 1.7 1 0 0 1 1 1 1 S1-like SAP PF02037.27 VBB29090.1 - 2.2e-10 40.1 0.8 5.1e-10 38.9 0.8 1.7 1 0 0 1 1 1 1 SAP domain EF-hand_7 PF13499.6 VBB29090.1 - 0.034 14.6 0.1 0.13 12.7 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair ApoO PF09769.9 VBB29090.1 - 0.089 12.8 0.0 8.9 6.3 0.1 2.8 2 1 0 2 2 2 0 Apolipoprotein O EGF_CA PF07645.15 VBB29093.1 - 5.8e-74 244.1 155.7 1.8e-10 40.9 7.8 12.7 12 2 2 14 14 14 10 Calcium-binding EGF domain cEGF PF12662.7 VBB29093.1 - 4.4e-46 154.4 86.0 1.4e-08 34.5 2.5 11.2 11 0 0 11 11 11 9 Complement Clr-like EGF-like FXa_inhibition PF14670.6 VBB29093.1 - 5.2e-26 90.6 136.1 6.8e-08 32.7 5.3 11.7 11 1 1 12 12 12 9 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 VBB29093.1 - 1.3e-18 66.9 105.6 2e-05 24.7 5.1 12.0 10 2 0 11 11 11 10 EGF domain hEGF PF12661.7 VBB29093.1 - 2.4e-10 40.6 104.9 0.0011 19.6 2.4 14.1 14 1 0 14 14 14 6 Human growth factor-like EGF EGF PF00008.27 VBB29093.1 - 1.6e-08 34.7 115.7 0.00019 21.6 4.4 13.5 13 2 1 14 14 14 7 EGF-like domain Plasmod_Pvs28 PF06247.11 VBB29093.1 - 0.22 11.8 97.5 0.13 12.6 2.1 11.4 9 2 1 10 10 10 0 Pvs28 EGF domain Ydr279_N PF17745.1 VBB29094.1 - 8.7e-05 22.7 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain MutS_V PF00488.21 VBB29095.1 - 1.3e-59 201.4 0.1 5.3e-59 199.4 0.0 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 VBB29095.1 - 5.3e-30 105.1 1.6 1.3e-29 103.8 1.6 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 VBB29095.1 - 4e-08 33.5 0.8 9.4e-08 32.3 0.8 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 VBB29095.1 - 8.5e-06 26.0 0.1 2.7e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 MutS domain I MutS_II PF05188.17 VBB29095.1 - 0.0023 18.2 0.2 0.0065 16.7 0.2 1.8 1 0 0 1 1 1 1 MutS domain II Peptidase_M3 PF01432.20 VBB29096.1 - 1.1e-78 265.5 0.1 1.6e-78 265.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 ACBP PF00887.19 VBB29097.1 - 0.0028 17.8 0.0 0.0034 17.6 0.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein TFIID_30kDa PF03540.13 VBB29098.1 - 7.9e-23 80.2 1.6 1.9e-22 79.0 0.3 2.3 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit FERM_C PF09380.10 VBB29099.1 - 6e-11 42.6 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 VBB29099.1 - 1.7e-09 38.1 0.0 5.4e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 VBB29099.1 - 4.4e-05 23.3 0.0 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 FERM N-terminal domain PROCN PF08083.11 VBB29100.1 - 6.6e-233 772.7 7.9 6.6e-233 772.7 7.9 2.2 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 VBB29100.1 - 3e-127 422.9 1.1 5.3e-127 422.1 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 VBB29100.1 - 2.2e-88 293.9 6.9 5e-88 292.8 6.2 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 VBB29100.1 - 2.2e-86 287.7 2.1 5.2e-86 286.5 2.1 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 VBB29100.1 - 1.4e-72 242.1 0.1 2.7e-72 241.1 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 VBB29100.1 - 1.2e-51 173.8 0.1 2.9e-51 172.6 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 VBB29100.1 - 4.3e-47 158.4 1.4 6.7e-47 157.8 0.3 2.0 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 VBB29100.1 - 2.4e-07 30.7 0.0 5.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3337 PF11816.8 VBB29101.1 - 1.9e-40 138.5 0.2 4.8e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 VBB29101.1 - 1.7e-28 98.2 13.7 5.7e-05 23.8 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29101.1 - 1.2e-05 25.5 2.3 0.29 11.4 0.1 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB29101.1 - 0.013 14.5 0.2 0.37 9.7 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 VBB29101.1 - 0.015 14.0 4.4 0.38 9.3 0.5 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB29101.1 - 0.13 11.6 0.0 0.3 10.3 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain RAWUL PF16207.5 VBB29101.1 - 0.18 12.5 0.1 0.41 11.3 0.1 1.7 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like HCNGP PF07818.13 VBB29104.1 - 4e-28 97.9 0.1 9.9e-28 96.6 0.1 1.7 1 0 0 1 1 1 1 HCNGP-like protein SEEEED PF14797.6 VBB29104.1 - 10 6.3 28.7 4.3 7.5 15.3 2.7 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex LSM PF01423.22 VBB29105.1 - 1e-12 47.6 0.0 1.2e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain Cyclin_N PF00134.23 VBB29106.1 - 4.3e-26 91.1 0.4 2.5e-23 82.2 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 VBB29106.1 - 7.1e-09 35.8 0.4 7.1e-09 35.8 0.4 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Plexin_cytopl PF08337.12 VBB29107.1 - 9.1e-206 684.8 6.4 1.3e-205 684.4 6.4 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 VBB29107.1 - 5.5e-51 173.7 0.1 8.3e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 VBB29107.1 - 1.2e-29 102.2 0.5 1.5e-08 34.6 0.1 5.0 4 0 0 4 4 4 4 IPT/TIG domain TIG_2 PF18020.1 VBB29107.1 - 5.5e-21 75.0 0.0 2.9e-20 72.7 0.0 2.3 2 0 0 2 2 2 1 TIG domain found in plexin TIG_plexin PF17960.1 VBB29107.1 - 3.2e-20 71.9 0.0 5e-17 61.7 0.0 3.4 2 0 0 2 2 2 2 TIG domain PSI PF01437.25 VBB29107.1 - 3e-17 62.9 50.1 3.9e-08 33.7 11.7 4.3 3 0 0 3 3 3 3 Plexin repeat Zip PF02535.22 VBB29108.1 - 6.7e-41 140.6 19.0 4.8e-27 95.0 3.3 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2721 PF11026.8 VBB29108.1 - 0.0052 16.7 0.7 0.0052 16.7 0.7 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF2721) DUF2207 PF09972.9 VBB29108.1 - 4.2 6.0 8.0 0.53 9.0 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) E1_dh PF00676.20 VBB29109.1 - 3.7e-107 357.7 0.0 4.6e-107 357.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 VBB29109.1 - 0.019 14.7 0.2 0.053 13.3 0.2 1.8 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 VBB29109.1 - 0.099 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase ShK PF01549.24 VBB29110.1 - 0.058 13.9 1.5 0.12 12.9 1.5 1.5 1 0 0 1 1 1 0 ShK domain-like DUF2154 PF09922.9 VBB29110.1 - 0.22 11.4 4.8 3.3 7.6 0.1 4.3 4 0 0 4 4 4 0 Cell wall-active antibiotics response 4TMS YvqF Metallophos PF00149.28 VBB29111.1 - 1.2e-10 42.3 0.2 1.7e-10 41.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 VBB29111.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily CxC6 PF18721.1 VBB29112.1 - 0.07 13.4 1.8 0.25 11.6 1.8 2.0 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Pkinase PF00069.25 VBB29113.1 - 5.8e-40 137.3 5.8 1e-21 77.5 0.3 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29113.1 - 9.5e-11 41.5 4.3 2.7e-10 40.0 0.3 2.9 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB29113.1 - 0.005 15.7 0.2 0.025 13.4 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase PAP2_C PF14360.6 VBB29114.1 - 2.5e-22 79.2 7.4 2.5e-22 79.2 7.4 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 VBB29114.1 - 2.9e-05 23.8 5.8 2.9e-05 23.8 5.8 2.3 2 1 1 3 3 3 1 PAP2 superfamily E7 PF00527.18 VBB29114.1 - 1.9 8.8 6.0 0.15 12.3 0.9 1.8 2 0 0 2 2 2 0 E7 protein, Early protein FSAP_sig_propep PF03032.15 VBB29114.1 - 5.2 7.2 10.8 18 5.4 10.8 2.0 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF2721 PF11026.8 VBB29114.1 - 6.7 6.6 11.5 2.2 8.2 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) CarboxypepD_reg PF13620.6 VBB29116.1 - 1.8e-38 130.7 0.1 2.3e-08 34.2 0.0 9.4 9 0 0 9 9 9 7 Carboxypeptidase regulatory-like domain Cation_efflux PF01545.21 VBB29116.1 - 4.1e-36 124.6 25.8 7e-36 123.8 25.8 1.4 1 0 0 1 1 1 1 Cation efflux family SdrD_B PF17210.3 VBB29116.1 - 6.3e-20 71.5 1.3 0.0053 17.0 0.0 8.4 8 1 1 9 9 9 4 SdrD B-like domain SpaA PF17802.1 VBB29116.1 - 2.8e-13 50.0 0.5 0.031 14.6 0.0 6.7 4 1 2 6 6 6 3 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 VBB29116.1 - 8e-12 45.0 3.5 0.0017 18.3 0.1 8.0 8 0 0 8 8 8 2 CarboxypepD_reg-like domain bMG3 PF11974.8 VBB29116.1 - 1.5e-09 37.8 0.0 1.9 8.6 0.0 7.4 8 0 0 8 8 8 2 Bacterial alpha-2-macroglobulin MG3 domain DUF2012 PF09430.10 VBB29116.1 - 8e-09 35.7 0.1 0.08 13.1 0.0 4.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2012) DUF4198 PF10670.9 VBB29116.1 - 0.00017 22.0 0.0 0.53 10.6 0.0 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4198) DUF1416 PF07210.12 VBB29116.1 - 0.011 15.6 0.0 0.13 12.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1416) TTR-52 PF01060.23 VBB29116.1 - 0.012 16.3 0.0 15 6.3 0.0 4.1 3 0 0 3 3 3 0 Transthyretin-like family Big_1 PF02369.16 VBB29116.1 - 0.043 13.8 0.6 2.7 8.1 0.0 4.3 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 1) 14-3-3 PF00244.20 VBB29117.1 - 3.3e-126 419.2 9.1 1.8e-68 230.4 0.2 3.0 3 0 0 3 3 3 3 14-3-3 protein Peptidase_C98 PF15499.6 VBB29117.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase EpoR_lig-bind PF09067.10 VBB29117.1 - 0.02 15.1 0.1 0.66 10.2 0.0 2.4 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding TPR_12 PF13424.6 VBB29117.1 - 0.051 13.9 2.2 9.1 6.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RAD51_interact PF15696.5 VBB29117.1 - 0.14 12.3 0.0 7.8 6.7 0.0 2.4 2 0 0 2 2 2 0 RAD51 interacting motif Virulence_fact PF13769.6 VBB29117.1 - 2.2 8.5 6.2 1.8 8.8 0.4 3.3 4 0 0 4 4 4 0 Virulence factor CTU2 PF10288.9 VBB29119.1 - 0.00031 20.9 3.3 0.00031 20.9 3.3 2.4 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 TF_Zn_Ribbon PF08271.12 VBB29119.1 - 1.2 8.7 5.1 0.3 10.6 0.9 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2797 PF10977.8 VBB29119.1 - 1.3 8.8 4.8 4.5 7.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) TMC PF07810.13 VBB29120.1 - 1.7e-35 121.9 6.0 3.6e-35 120.9 4.5 2.2 2 0 0 2 2 2 1 TMC domain Peptidase_M2 PF01401.18 VBB29121.1 - 2.6e-168 561.2 7.3 3.2e-168 560.9 7.3 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme EB PF01683.18 VBB29121.1 - 5.5e-06 26.6 0.5 1.2e-05 25.5 0.5 1.5 1 0 0 1 1 1 1 EB module 7tm_1 PF00001.21 VBB29122.1 - 5.4e-59 199.7 15.6 8.3e-59 199.1 15.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 VBB29123.1 - 1e-63 215.2 0.0 2.9e-63 213.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29123.1 - 8.9e-36 123.5 0.0 1.4e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 VBB29123.1 - 2.7e-21 75.8 0.1 6.3e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 VBB29123.1 - 0.0098 16.6 0.1 0.025 15.3 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 VBB29123.1 - 0.016 14.2 0.1 0.05 12.6 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 VBB29123.1 - 0.069 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 VBB29123.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lipase_3 PF01764.25 VBB29124.1 - 1.9e-19 69.9 0.0 3.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) eIF2A PF08662.11 VBB29125.1 - 5.1e-71 238.6 0.0 1.5e-70 237.0 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3287 PF11690.8 VBB29125.1 - 0.37 10.5 13.0 0.074 12.8 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Tubulin PF00091.25 VBB29126.1 - 1.7e-58 198.1 0.8 3.7e-57 193.7 0.0 2.7 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB29126.1 - 1.9e-43 147.6 0.1 3.2e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 VBB29126.1 - 1.4e-05 25.3 0.0 4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 VBB29126.1 - 0.05 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin PF00091.25 VBB29127.1 - 6.3e-70 235.4 0.0 1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB29127.1 - 3.3e-43 146.8 0.1 5.2e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 VBB29127.1 - 2.4e-05 24.6 0.0 6.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 VBB29127.1 - 0.0082 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 VBB29127.1 - 0.018 14.2 0.0 0.042 13.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Thiolase_N PF00108.23 VBB29128.1 - 5.9e-77 258.5 0.8 7.9e-77 258.1 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 VBB29128.1 - 9.1e-37 125.4 0.0 2.6e-36 124.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 VBB29128.1 - 0.00011 21.9 0.1 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain TPR_2 PF07719.17 VBB29129.1 - 2.4e-15 55.3 17.3 0.0036 17.3 0.2 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB29129.1 - 8.4e-15 53.9 14.3 0.00028 20.5 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB29129.1 - 2.4e-11 42.8 0.1 0.011 15.7 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB29129.1 - 2.4e-09 36.7 13.8 0.24 11.7 0.0 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29129.1 - 1e-06 28.9 24.9 3.9e-06 27.1 0.0 6.9 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29129.1 - 6.5e-06 26.5 8.3 5.1 8.2 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB29129.1 - 3.3e-05 23.6 1.7 0.11 12.4 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29129.1 - 0.00068 19.8 2.1 4.8 7.8 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29129.1 - 0.00092 19.7 8.5 0.34 11.4 0.0 6.5 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_3 PF07720.12 VBB29129.1 - 0.0015 18.4 7.8 4.9 7.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29129.1 - 0.0048 17.1 23.2 0.21 11.8 0.8 6.8 4 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 VBB29129.1 - 0.0088 15.7 8.3 1.1 9.0 0.0 4.7 6 0 0 6 6 6 2 TPR repeat Nup96 PF12110.8 VBB29130.1 - 6.2e-46 156.8 0.3 1.1e-45 156.1 0.3 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 VBB29130.1 - 1.6e-44 151.6 0.0 4.2e-44 150.3 0.0 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 VBB29130.1 - 2e-14 54.2 156.4 0.00087 20.1 31.1 7.0 3 2 3 6 6 6 4 Nucleoporin FG repeat region TAL_FSA PF00923.19 VBB29132.1 - 9e-84 281.2 0.0 2.8e-83 279.6 0.0 1.6 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CLAG PF03805.13 VBB29132.1 - 0.028 12.0 0.1 0.03 11.9 0.1 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein DUF3886 PF13025.6 VBB29133.1 - 0.047 13.9 1.6 0.06 13.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) TFIID-18kDa PF02269.16 VBB29134.1 - 1.4e-12 47.4 0.3 6.9e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Ion_trans_2 PF07885.16 VBB29134.1 - 0.0014 18.5 0.4 0.0025 17.7 0.4 1.4 1 0 0 1 1 1 1 Ion channel Pkinase PF00069.25 VBB29135.1 - 9.5e-72 241.5 0.0 1.1e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29135.1 - 2.7e-44 151.4 0.0 3.4e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29135.1 - 0.00051 19.5 0.0 0.024 14.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 VBB29135.1 - 0.002 17.2 0.0 0.0036 16.3 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 VBB29135.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB29135.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 VBB29135.1 - 0.045 13.4 0.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Ribosomal_L10 PF00466.20 VBB29136.1 - 2.1e-22 79.1 1.6 4.8e-22 78.0 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 VBB29136.1 - 1.7e-20 72.8 0.0 4.4e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P DUF1768 PF08719.11 VBB29137.1 - 3e-28 99.1 0.0 7.2e-28 97.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 VBB29137.1 - 0.17 11.7 0.0 2.1 8.1 0.0 2.5 2 1 0 2 2 2 0 Bacteriophage protein GP30.3 zf-CCCH PF00642.24 VBB29138.1 - 7.1e-20 70.4 11.7 7.4e-10 38.5 2.3 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB29138.1 - 1.8e-07 31.0 13.0 8.4e-05 22.5 3.2 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB29138.1 - 3.1e-05 23.6 15.2 0.0013 18.5 1.7 2.9 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 VBB29138.1 - 0.00019 22.1 6.9 0.043 14.5 0.8 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 VBB29138.1 - 0.002 18.6 8.3 0.41 11.2 0.6 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger OAD_gamma PF04277.13 VBB29140.1 - 0.036 14.6 0.2 0.036 14.6 0.2 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CitMHS PF03600.16 VBB29140.1 - 0.05 12.8 0.1 0.053 12.7 0.1 1.0 1 0 0 1 1 1 0 Citrate transporter UL41A PF17591.2 VBB29140.1 - 0.13 12.4 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL41A Epiglycanin_C PF14654.6 VBB29140.1 - 0.17 12.0 0.5 0.27 11.3 0.5 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Vpu PF00558.19 VBB29140.1 - 1.4 8.7 4.4 0.24 11.2 0.8 1.5 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.20 VBB29140.1 - 1.6 8.7 4.9 2.6 8.0 4.9 1.4 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 VBB29142.1 - 1e-20 74.2 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29142.1 - 1.5e-11 44.1 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB29142.1 - 0.0014 17.5 0.1 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 VBB29143.1 - 4.5e-06 26.4 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 VBB29143.1 - 0.41 9.4 16.6 0.44 9.3 16.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain ALMT PF11744.8 VBB29143.1 - 1.3 7.7 3.4 1.5 7.6 3.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC45 PF02724.14 VBB29143.1 - 1.5 7.0 11.1 1.8 6.7 11.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4614 PF15391.6 VBB29143.1 - 1.9 8.5 16.0 2.7 7.9 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) MAJIN PF15077.6 VBB29143.1 - 2 8.1 12.2 2.5 7.8 12.2 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein SWIRM-assoc_2 PF16496.5 VBB29143.1 - 2.2 7.1 13.2 2.7 6.8 13.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal FAM76 PF16046.5 VBB29143.1 - 3.2 7.0 12.6 4.8 6.4 12.6 1.4 1 1 0 1 1 1 0 FAM76 protein Hid1 PF12722.7 VBB29143.1 - 4.6 5.2 9.7 5.2 5.1 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.22 VBB29144.1 - 1.5e-17 63.2 0.0 6.5e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB29144.1 - 0.027 14.3 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 VBB29144.1 - 0.065 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 VBB29144.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FEZ PF07763.13 VBB29146.1 - 1.7e-80 270.3 4.9 2.2e-80 269.9 4.9 1.1 1 0 0 1 1 1 1 FEZ-like protein ER PF01133.17 VBB29146.1 - 0.022 14.8 0.4 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 Enhancer of rudimentary FTO_CTD PF12934.7 VBB29146.1 - 0.11 12.2 3.1 0.079 12.7 0.6 2.0 2 0 0 2 2 2 0 FTO C-terminal domain WD40 PF00400.32 VBB29147.1 - 1.4e-09 38.4 9.0 0.075 13.9 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 VBB29147.1 - 0.00013 21.8 0.2 0.00031 20.6 0.2 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 VBB29147.1 - 0.00037 20.8 0.2 0.037 14.3 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Snf7 PF03357.21 VBB29148.1 - 9.9e-21 74.1 10.6 1.2e-20 73.9 10.6 1.1 1 0 0 1 1 1 1 Snf7 Suf PF05843.14 VBB29148.1 - 0.046 13.7 0.1 0.046 13.7 0.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Plant_NMP1 PF06694.11 VBB29148.1 - 0.17 10.9 1.2 0.19 10.8 1.2 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) TraF_2 PF13729.6 VBB29148.1 - 0.79 9.0 4.0 0.99 8.7 4.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein cNMP_binding PF00027.29 VBB29149.1 - 1.4e-19 70.0 0.0 2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Neur_chan_LBD PF02931.23 VBB29151.1 - 6.7e-45 153.2 0.1 1e-44 152.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB29151.1 - 7.9e-27 94.8 4.9 2.4e-24 86.7 0.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Virul_fac_BrkB PF03631.15 VBB29151.1 - 0.026 14.2 0.9 0.026 14.2 0.9 1.4 2 0 0 2 2 2 0 Virulence factor BrkB AA_permease PF00324.21 VBB29152.1 - 1.7e-61 208.3 27.1 2.6e-45 154.9 3.3 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 VBB29152.1 - 4.7e-27 95.1 0.3 1.6e-08 34.1 0.0 3.2 2 1 1 3 3 3 3 Solute carrier family 12 Bac_GH3_C PF18034.1 VBB29152.1 - 0.0037 17.0 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial Glycosyl hydrolase family 3 C-terminal domain GPR15L PF15854.5 VBB29152.1 - 0.027 14.7 0.6 0.14 12.4 0.2 2.4 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 MciZ PF13072.6 VBB29152.1 - 0.16 11.8 0.3 0.37 10.7 0.3 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Motile_Sperm PF00635.26 VBB29153.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.5 1 1 0 1 1 1 0 MSP (Major sperm protein) domain SAND PF01342.21 VBB29154.1 - 2.3e-22 78.5 0.1 4.4e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 SAND domain Pkinase_Tyr PF07714.17 VBB29156.1 - 2.1e-38 132.1 3.1 3.8e-37 128.0 3.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB29156.1 - 3.6e-22 79.0 3.6 2.5e-21 76.2 3.6 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 VBB29156.1 - 0.042 13.1 0.4 0.41 9.9 0.4 2.0 1 1 0 1 1 1 0 Kinase-like HLH PF00010.26 VBB29157.1 - 2.9e-05 24.0 0.7 4.4e-05 23.3 0.7 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TTRAP PF14203.6 VBB29157.1 - 0.0052 16.7 0.3 0.0088 16.0 0.3 1.4 1 0 0 1 1 1 1 Putative tranposon-transfer assisting protein ERK-JNK_inhib PF15002.6 VBB29157.1 - 0.058 13.1 0.6 0.067 12.9 0.6 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Dzip-like_N PF13815.6 VBB29157.1 - 0.13 12.3 1.3 0.15 12.0 0.7 1.5 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HLH PF00010.26 VBB29158.1 - 0.0032 17.4 1.7 0.011 15.6 1.3 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Trypsin PF00089.26 VBB29160.1 - 2.8e-06 27.3 0.2 5.9e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Trypsin DUF4845 PF16137.5 VBB29160.1 - 0.013 16.4 0.0 0.025 15.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) DUF316 PF03761.15 VBB29160.1 - 0.042 13.4 0.2 0.062 12.9 0.2 1.3 1 1 0 1 1 1 0 Chymotrypsin family Peptidase-S1 DEAD PF00270.29 VBB29161.1 - 1.9e-45 154.8 0.7 1.9e-45 154.8 0.7 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB29161.1 - 3.3e-33 114.4 0.5 4.3e-32 110.8 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB29161.1 - 4e-08 33.4 0.0 6.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 VBB29161.1 - 9.1e-05 22.8 0.2 0.00035 20.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 VBB29161.1 - 0.00016 21.5 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 VBB29161.1 - 0.0033 16.8 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 VBB29161.1 - 0.0071 16.6 0.1 0.026 14.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 VBB29161.1 - 0.0089 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Helicase Flavi_DEAD PF07652.14 VBB29161.1 - 0.017 15.1 0.2 0.075 13.0 0.2 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 VBB29161.1 - 0.068 12.7 0.2 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain fragilysinNterm PF16376.5 VBB29161.1 - 0.075 12.8 0.6 0.6 9.9 0.1 2.6 3 0 0 3 3 3 0 N-terminal domain of fragilysin SH3_9 PF14604.6 VBB29162.1 - 4.7e-16 58.4 0.0 8.3e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.20 VBB29162.1 - 7.8e-15 55.6 0.2 1.4e-14 54.7 0.0 1.5 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 VBB29162.1 - 1.6e-13 50.0 0.1 2.9e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB29162.1 - 2.6e-12 46.2 0.0 4.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3369 PF11849.8 VBB29162.1 - 0.018 15.3 0.6 0.089 13.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) betaPIX_CC PF16523.5 VBB29163.1 - 3.2e-33 113.4 8.5 5.3e-33 112.7 8.5 1.4 1 0 0 1 1 1 1 betaPIX coiled coil CCDC144C PF14915.6 VBB29163.1 - 0.001 18.2 5.1 0.0016 17.6 5.1 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CREPT PF16566.5 VBB29163.1 - 0.0045 17.2 4.6 0.0045 17.2 4.6 1.7 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour GlutR_dimer PF00745.20 VBB29163.1 - 0.0087 16.5 2.5 0.018 15.5 2.5 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain RhoGEF67_u2 PF16614.5 VBB29163.1 - 0.046 13.8 0.9 1.2 9.2 0.1 2.7 2 1 1 3 3 3 0 Unstructured region two on RhoGEF 6 and 7 OmpH PF03938.14 VBB29163.1 - 0.092 13.1 5.6 0.15 12.4 5.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 VBB29163.1 - 0.1 12.6 4.5 0.17 11.9 4.5 1.3 1 0 0 1 1 1 0 Laminin Domain II ABC_tran_Xtn PF12848.7 VBB29163.1 - 0.2 11.7 4.0 0.52 10.4 4.0 1.6 1 0 0 1 1 1 0 ABC transporter FlxA PF14282.6 VBB29163.1 - 0.41 10.6 10.0 0.85 9.6 10.0 1.5 1 0 0 1 1 1 0 FlxA-like protein YabA PF06156.13 VBB29163.1 - 0.59 10.8 4.7 1.4 9.6 4.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Fasciclin PF02469.22 VBB29164.1 - 5e-30 104.3 0.3 6.1e-13 49.1 0.1 5.2 4 2 0 4 4 4 4 Fasciclin domain DASH_Dad3 PF08656.10 VBB29165.1 - 0.042 13.9 0.3 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad3 NPL4 PF05021.15 VBB29166.1 - 1.3e-115 386.0 0.0 1.7e-115 385.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 VBB29166.1 - 5e-58 195.4 1.7 1.1e-57 194.3 1.7 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 VBB29166.1 - 0.0034 16.7 3.8 0.0034 16.7 3.8 3.0 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others MTES_1575 PF18741.1 VBB29167.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 REase_MTES_1575 TDP43_N PF18694.1 VBB29168.1 - 2e-24 85.2 0.0 4.2e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 VBB29168.1 - 1.5e-15 56.7 0.8 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 VBB29169.1 - 8.8e-68 228.5 0.0 1.5e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29169.1 - 1.6e-31 109.5 0.0 2.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29169.1 - 9.1e-06 25.2 0.4 0.00077 18.9 0.1 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 VBB29169.1 - 0.02 14.3 0.2 0.093 12.1 0.3 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM144 PF07857.12 VBB29170.1 - 5e-104 347.9 21.5 5.6e-104 347.7 21.5 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 VBB29170.1 - 2.8e-06 26.9 3.6 2.8e-06 26.9 3.6 2.7 1 1 1 3 3 3 1 Sugar transport protein TK PF00265.18 VBB29170.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Thymidine kinase Gram_pos_anchor PF00746.21 VBB29170.1 - 0.6 10.1 3.1 2.9 7.9 0.0 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF2149 PF09919.9 VBB29170.1 - 1.4 9.2 3.8 4.9 7.5 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DOCK_N PF16172.5 VBB29171.1 - 2.2e-40 138.7 0.1 4.5e-40 137.7 0.1 1.5 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 VBB29171.1 - 3.1e-37 128.3 0.0 5.4e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 VBB29171.1 - 0.022 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain TipAS PF07739.13 VBB29171.1 - 0.037 14.6 0.1 0.083 13.4 0.1 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain SH3_2 PF07653.17 VBB29171.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Claudin_3 PF06653.11 VBB29172.1 - 0.0039 17.1 7.4 0.22 11.5 4.8 2.1 2 0 0 2 2 2 2 Tight junction protein, Claudin-like DUF1980 PF09323.10 VBB29172.1 - 0.092 12.7 0.9 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PMP22_Claudin PF00822.20 VBB29172.1 - 0.18 11.7 4.9 0.91 9.4 0.0 2.7 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family GSG-1 PF07803.11 VBB29172.1 - 0.54 10.2 0.1 0.54 10.2 0.1 1.6 2 0 0 2 2 2 0 GSG1-like protein DHHC PF01529.20 VBB29172.1 - 0.67 10.1 12.6 1.4 9.1 4.0 2.9 2 1 0 3 3 3 0 DHHC palmitoyltransferase FtsX PF02687.21 VBB29172.1 - 1.5 9.4 17.1 41 4.7 6.5 2.6 1 1 1 2 2 2 0 FtsX-like permease family Saf_2TM PF18303.1 VBB29172.1 - 2.7 7.6 7.3 6 6.4 0.3 3.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Bac_export_2 PF01312.19 VBB29172.1 - 6.5 5.9 7.0 27 3.8 7.0 1.9 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Corona_S2 PF01601.16 VBB29173.1 - 0.00053 18.6 5.6 0.00079 18.0 5.6 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein TMEM52 PF14979.6 VBB29173.1 - 0.025 14.5 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane 52 LAT PF15234.6 VBB29173.1 - 0.38 10.5 5.9 0.58 9.9 5.9 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells CAP_N PF01213.19 VBB29173.1 - 0.69 9.3 5.9 1.1 8.7 5.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2046 PF09755.9 VBB29174.1 - 2.2e-64 217.6 39.8 4.7e-64 216.5 39.8 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) CENP-Q PF13094.6 VBB29174.1 - 0.0012 19.0 11.2 0.0012 19.0 11.2 4.0 1 1 2 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4094 PF13334.6 VBB29174.1 - 0.27 11.7 20.3 0.04 14.3 3.4 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TMF_TATA_bd PF12325.8 VBB29174.1 - 1 9.6 38.2 0.78 10.0 6.8 4.4 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding FAM110_C PF14160.6 VBB29174.1 - 1.1 10.3 10.1 0.14 13.2 3.7 2.7 2 1 0 2 2 2 0 Centrosome-associated C terminus UPF0231 PF06062.11 VBB29174.1 - 2.2 8.6 9.5 1.1 9.5 0.2 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Baculo_PEP_C PF04513.12 VBB29174.1 - 2.5 8.2 11.4 26 4.9 0.0 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 VBB29174.1 - 6.6 7.1 41.9 0.16 12.2 1.0 5.9 3 1 3 6 6 6 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 VBB29174.1 - 6.8 7.2 17.8 7.4 7.0 0.7 5.7 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) ZZ PF00569.17 VBB29175.1 - 2.7e-12 46.3 5.2 8.6e-12 44.7 5.2 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-Di19 PF05605.12 VBB29175.1 - 4.5e-09 36.5 1.0 1.1e-08 35.2 0.5 2.0 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Med10 PF09748.9 VBB29175.1 - 0.39 10.7 2.8 2.9 7.9 0.0 3.1 4 0 0 4 4 4 0 Transcription factor subunit Med10 of Mediator complex GCD14 PF08704.10 VBB29177.1 - 3.9e-56 190.5 0.0 6.7e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit ESCRT-II PF05871.12 VBB29177.1 - 1.4e-47 161.4 0.3 2.5e-47 160.6 0.3 1.4 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.17 VBB29177.1 - 4e-05 23.2 0.0 6.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 VBB29177.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 VBB29177.1 - 0.008 17.2 0.0 0.017 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB29177.1 - 0.015 16.0 0.0 0.045 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 VBB29177.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Carm_PH PF17888.1 VBB29178.1 - 2.9e-27 94.9 0.1 7.2e-27 93.6 0.1 1.7 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_4 PF12799.7 VBB29178.1 - 0.00035 20.9 32.0 0.064 13.7 2.5 7.1 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB29178.1 - 0.01 15.8 33.7 1.3 9.2 0.0 10.3 11 0 0 11 11 11 0 Leucine Rich repeat Orn_Arg_deC_N PF02784.16 VBB29180.1 - 2.4e-33 115.6 0.0 3.4e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 VBB29180.1 - 6.2e-08 32.8 0.0 9.2e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GDP_Man_Dehyd PF16363.5 VBB29181.1 - 1.5e-13 50.9 0.4 1.1e-12 48.0 0.4 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 VBB29181.1 - 6.3e-09 35.7 1.1 3e-07 30.2 0.1 2.4 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.10 VBB29181.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 KR domain TAFII28 PF04719.14 VBB29182.1 - 3.6e-22 78.2 0.1 8.1e-22 77.1 0.0 1.6 2 0 0 2 2 2 1 hTAFII28-like protein conserved region ECH_2 PF16113.5 VBB29183.1 - 1.8e-117 392.6 0.0 7.6e-112 374.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 VBB29183.1 - 1.5e-24 86.7 0.1 6.8e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase RST PF12174.8 VBB29183.1 - 0.27 11.2 1.7 32 4.5 0.2 3.6 4 0 0 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain PP2C PF00481.21 VBB29184.1 - 4.7e-84 282.0 0.0 6.9e-84 281.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 VBB29184.1 - 6.9e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C RPN7 PF10602.9 VBB29186.1 - 1.5e-56 190.8 0.4 4e-56 189.5 0.4 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 VBB29186.1 - 5.8e-16 58.9 1.3 3.2e-15 56.5 0.0 2.8 2 0 0 2 2 2 1 PCI domain Myb_DNA-bind_2 PF08914.11 VBB29186.1 - 0.033 14.4 0.5 0.075 13.2 0.5 1.6 1 0 0 1 1 1 0 Rap1 Myb domain SPK PF04435.18 VBB29186.1 - 0.11 12.9 3.8 0.096 13.1 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF545) UPF0016 PF01169.19 VBB29187.1 - 2.2e-41 140.0 22.8 2.1e-22 79.2 6.1 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3112 PF11309.8 VBB29187.1 - 0.0039 16.7 1.1 0.81 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) MAD PF05557.13 VBB29187.1 - 0.093 11.1 0.2 0.13 10.6 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Pkinase PF00069.25 VBB29188.1 - 1e-39 136.5 0.0 1.5e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29188.1 - 4.7e-19 68.7 0.0 5.2e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Neur_chan_LBD PF02931.23 VBB29190.1 - 3e-50 170.7 0.3 4.6e-50 170.0 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain hemP PF10636.9 VBB29190.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP Neur_chan_LBD PF02931.23 VBB29192.1 - 2.8e-40 138.1 1.0 4.8e-40 137.3 1.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB29192.1 - 8e-33 114.5 5.6 4.6e-29 102.1 2.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region WBS_methylT PF12589.8 VBB29193.1 - 4.9e-16 59.3 7.3 7.9e-16 58.6 7.3 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 VBB29193.1 - 6.6e-11 42.7 0.0 1.8e-10 41.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB29193.1 - 2.5e-10 40.9 0.0 8.2e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB29193.1 - 2e-05 24.4 0.0 4.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB29193.1 - 5.1e-05 23.9 0.0 0.0001 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB29193.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 VBB29193.1 - 0.00021 21.1 0.1 0.00049 19.9 0.0 1.6 2 0 0 2 2 2 1 DNA methylase PCMT PF01135.19 VBB29193.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 VBB29193.1 - 0.055 13.8 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 VBB29193.1 - 0.066 12.5 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 VBB29193.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DEAD PF00270.29 VBB29194.1 - 5.3e-13 49.1 0.0 1.5e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB29194.1 - 1.6e-11 44.5 0.0 2.1e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 VBB29194.1 - 7.7e-08 32.7 0.0 3.7e-07 30.5 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 VBB29195.1 - 6.4e-37 127.1 0.0 1e-18 68.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 VBB29195.1 - 1.1e-10 41.4 6.4 0.0027 17.2 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 VBB29195.1 - 1.4e-09 38.2 4.0 0.12 12.2 1.1 4.4 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 VBB29195.1 - 1.1e-08 34.8 3.7 2.8e-08 33.4 3.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_22 PF13401.6 VBB29195.1 - 3.6e-06 27.3 0.6 0.0014 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 VBB29195.1 - 9.6e-06 26.0 0.0 0.056 13.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 VBB29195.1 - 1.3e-05 25.2 0.1 0.07 13.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 VBB29195.1 - 1.4e-05 25.1 0.3 0.0059 16.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 VBB29195.1 - 1.9e-05 25.1 0.0 0.35 11.3 0.0 3.0 2 2 0 2 2 2 2 AAA ATPase domain TsaE PF02367.17 VBB29195.1 - 0.00014 21.9 0.9 0.13 12.2 0.0 3.4 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 VBB29195.1 - 0.0006 19.5 1.4 0.74 9.6 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 VBB29195.1 - 0.00067 19.5 2.9 0.43 10.2 0.6 3.1 3 1 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 VBB29195.1 - 0.00081 19.4 0.6 0.62 10.0 0.3 3.0 2 1 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 VBB29195.1 - 0.00095 18.8 1.8 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 VBB29195.1 - 0.0016 18.8 0.0 2 8.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 VBB29195.1 - 0.003 18.1 0.0 4.7 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 VBB29195.1 - 0.0043 17.2 0.0 2.1 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 VBB29195.1 - 0.0046 17.2 0.4 1.9 8.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 VBB29195.1 - 0.0084 15.9 0.1 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 VBB29195.1 - 0.015 15.0 0.5 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 VBB29195.1 - 0.018 14.8 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E NB-ARC PF00931.22 VBB29195.1 - 0.019 14.2 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 VBB29195.1 - 0.02 14.6 0.6 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 VBB29195.1 - 0.048 13.6 1.0 1.8 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 VBB29195.1 - 0.052 13.1 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 VBB29195.1 - 0.077 12.7 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Toast_rack_N PF17115.5 VBB29195.1 - 0.092 13.0 0.0 1.5 9.2 0.0 2.7 3 0 0 3 3 3 0 N-terminal domain of toast_rack, DUF2154 AAA_14 PF13173.6 VBB29195.1 - 0.1 12.6 1.0 19 5.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 VBB29195.1 - 0.18 11.7 3.0 16 5.4 0.0 3.5 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 VBB29195.1 - 0.44 10.6 1.6 38 4.4 0.0 2.7 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 VBB29195.1 - 1.5 9.3 12.6 0.14 12.7 0.6 2.9 2 1 0 3 3 3 0 AAA domain RRM_1 PF00076.22 VBB29196.1 - 1.2e-29 101.9 0.0 3.4e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 VBB29196.1 - 1.3e-21 76.5 0.1 2.4e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 VBB29196.1 - 0.0084 16.2 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 VBB29196.1 - 0.048 13.7 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RNA_bind PF08675.11 VBB29196.1 - 0.23 11.5 0.0 1.4 9.0 0.0 2.1 2 1 0 2 2 2 0 RNA binding domain AAA_22 PF13401.6 VBB29197.1 - 0.0022 18.3 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 VBB29197.1 - 0.018 15.6 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 VBB29197.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 VBB29197.1 - 0.052 13.3 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 VBB29197.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 VBB29197.1 - 0.075 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 VBB29197.1 - 0.087 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 VBB29197.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 VBB29197.1 - 0.11 12.4 0.2 1.3 9.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Radical_SAM PF04055.21 VBB29198.1 - 1e-28 100.8 0.5 6.9e-28 98.1 0.0 2.7 4 0 0 4 4 4 1 Radical SAM superfamily UPF0004 PF00919.20 VBB29198.1 - 1.7e-27 95.3 0.6 4.5e-27 94.0 0.6 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 HA2 PF04408.23 VBB29198.1 - 1.7e-18 66.8 0.0 4.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 VBB29198.1 - 1e-16 61.2 0.0 3e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TRAM PF01938.20 VBB29198.1 - 2.8e-08 33.6 0.0 5.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 TRAM domain OB_NTP_bind PF07717.16 VBB29198.1 - 2.8e-05 24.4 0.0 9.2e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Foie-gras_1 PF11817.8 VBB29199.1 - 3.2e-30 105.6 0.1 5.2e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Ribosomal_S14 PF00253.21 VBB29199.1 - 1.2e-13 50.5 2.5 3.2e-13 49.2 2.5 1.8 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Gryzun PF07919.12 VBB29199.1 - 0.0036 16.1 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Exo_endo_phos_2 PF14529.6 VBB29199.1 - 0.024 14.5 0.1 0.073 12.9 0.1 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Cu_bind_CorA PF18252.1 VBB29199.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Copper(I)-binding protein CorA LcrR PF09621.10 VBB29199.1 - 0.096 12.1 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) DUF35_N PF12172.8 VBB29199.1 - 0.47 10.4 2.4 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TRAPPC10 PF12584.8 VBB29200.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TGFb_propeptide PF00688.18 VBB29200.1 - 0.019 14.7 0.4 0.068 12.9 0.4 1.9 1 1 0 1 1 1 0 TGF-beta propeptide PRIMA1 PF16101.5 VBB29200.1 - 0.29 11.2 3.0 0.54 10.3 3.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Nop14 PF04147.12 VBB29201.1 - 1.5e-124 417.2 54.9 4.1e-100 336.3 34.8 3.2 1 1 1 2 2 2 2 Nop14-like family Ssl1 PF04056.14 VBB29201.1 - 9.8e-62 208.2 0.4 2e-60 203.9 0.4 2.4 1 1 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 VBB29201.1 - 8e-10 39.3 0.0 2.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 VBB29201.1 - 0.0046 17.2 0.0 0.02 15.2 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.16 VBB29201.1 - 0.0055 16.6 1.0 0.018 14.9 1.0 1.9 1 0 0 1 1 1 1 HIT zinc finger Kinesin PF00225.23 VBB29202.1 - 2.4e-91 306.2 1.4 5.9e-91 304.8 1.4 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 VBB29202.1 - 3.2e-22 79.1 0.1 3.2e-22 79.1 0.1 2.7 2 0 0 2 2 2 1 Microtubule binding Chorismate_bind PF00425.18 VBB29202.1 - 0.066 12.8 1.6 0.15 11.6 1.6 1.5 1 0 0 1 1 1 0 chorismate binding enzyme Mucin2_WxxW PF13330.6 VBB29202.1 - 0.71 10.7 4.3 2.9 8.8 4.3 2.1 1 0 0 1 1 1 0 Mucin-2 protein WxxW repeating region Cnn_1N PF07989.11 VBB29202.1 - 1.9 8.7 22.6 5.8 7.1 1.4 4.1 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 MIT_C PF16565.5 VBB29203.1 - 1.1e-44 151.8 0.3 3.1e-44 150.4 0.1 1.8 2 0 0 2 2 2 1 Phospholipase D-like domain at C-terminus of MIT LAMTOR5 PF16672.5 VBB29204.1 - 8.9e-21 73.6 0.0 9.6e-21 73.5 0.0 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 RRM_1 PF00076.22 VBB29205.1 - 7.7e-31 105.7 0.0 9e-15 54.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) K_channel_TID PF07941.11 VBB29205.1 - 0.06 13.8 7.0 0.14 12.6 7.0 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4497 PF14924.6 VBB29205.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) AAA_23 PF13476.6 VBB29206.1 - 2.2e-29 103.4 2.2 2.2e-29 103.4 2.2 8.3 2 2 2 4 4 1 1 AAA domain MyTH4 PF00784.17 VBB29206.1 - 7.1e-17 61.9 0.0 7.1e-17 61.9 0.0 4.5 5 0 0 5 5 5 1 MyTH4 domain AAA_15 PF13175.6 VBB29206.1 - 5.1e-11 42.9 0.2 5.1e-11 42.9 0.2 5.0 2 1 1 5 5 3 1 AAA ATPase domain PH PF00169.29 VBB29206.1 - 7e-10 39.3 6.8 0.00042 20.8 0.0 4.2 4 0 0 4 4 3 2 PH domain SMC_N PF02463.19 VBB29206.1 - 2.4e-06 27.2 0.0 2.4e-06 27.2 0.0 3.2 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 VBB29206.1 - 2.2e-05 24.4 0.7 0.0002 21.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FERM_M PF00373.18 VBB29206.1 - 0.00071 20.0 0.4 0.0053 17.2 0.0 2.8 2 0 0 2 2 2 1 FERM central domain AAA_29 PF13555.6 VBB29206.1 - 0.0021 17.7 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 VBB29206.1 - 0.0032 17.1 0.0 0.0032 17.1 0.0 3.7 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.27 VBB29206.1 - 0.047 14.2 0.0 0.047 14.2 0.0 5.8 4 3 0 4 4 2 0 ABC transporter AAA_33 PF13671.6 VBB29206.1 - 0.096 12.8 0.0 0.69 10.1 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 VBB29206.1 - 0.17 12.2 5.3 0.21 11.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF3416 PF11896.8 VBB29206.1 - 0.41 10.9 2.9 0.83 9.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) Pkinase PF00069.25 VBB29207.1 - 1.2e-56 192.0 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29207.1 - 5.8e-35 120.8 0.1 7.9e-35 120.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29207.1 - 0.00011 21.6 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB29207.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB29207.1 - 0.011 14.7 1.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 VBB29207.1 - 0.2 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIBIOP_C PF04950.12 VBB29208.1 - 2.7e-113 378.2 0.0 5.1e-113 377.3 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 VBB29208.1 - 8.4e-08 32.2 0.2 0.0012 18.8 0.0 2.7 1 1 1 2 2 2 2 AARP2CN (NUC121) domain Pes-10 PF07149.11 VBB29208.1 - 2.4 7.2 13.1 4.5 6.2 13.1 1.4 1 0 0 1 1 1 0 Pes-10 SNase PF00565.17 VBB29209.1 - 1.7e-65 218.3 2.2 7e-21 74.7 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 VBB29209.1 - 3.1e-24 85.3 0.0 6.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF3297 PF11730.8 VBB29209.1 - 2.2e-05 24.2 0.4 0.00059 19.7 0.1 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF3297) PMSR PF01625.21 VBB29210.1 - 1.3e-40 139.1 4.1 1.8e-40 138.6 4.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase MKT1_N PF12247.8 VBB29210.1 - 0.038 14.4 0.7 0.074 13.4 0.7 1.6 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DUF445 PF04286.12 VBB29210.1 - 0.12 12.2 1.3 0.14 11.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) 60KD_IMP PF02096.20 VBB29210.1 - 0.91 9.4 3.6 1.5 8.7 3.6 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein MutS_V PF00488.21 VBB29212.1 - 2.9e-05 24.2 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V FSA_C PF10479.9 VBB29213.1 - 2.2e-43 148.4 8.6 2e-27 95.7 0.5 4.4 2 2 1 3 3 3 3 Fragile site-associated protein C-terminus Ornatin PF02088.15 VBB29213.1 - 0.099 12.4 1.2 0.28 11.0 0.8 2.0 2 0 0 2 2 2 0 Ornatin LisH PF08513.11 VBB29214.1 - 0.023 14.7 0.4 0.076 13.0 0.2 2.0 2 0 0 2 2 2 0 LisH CUE PF02845.16 VBB29214.1 - 0.088 12.5 2.3 0.12 12.1 0.4 2.2 2 0 0 2 2 2 0 CUE domain ALMT PF11744.8 VBB29214.1 - 0.53 9.1 10.0 0.67 8.7 10.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 VBB29214.1 - 3 6.3 18.9 4.2 5.8 18.9 1.2 1 0 0 1 1 1 0 Macoilin family LysE PF01810.18 VBB29215.1 - 0.0089 15.5 1.6 0.0089 15.5 1.6 1.7 1 1 1 2 2 2 1 LysE type translocator DUF2418 PF10332.9 VBB29215.1 - 0.17 12.4 4.3 0.57 10.7 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2418) DUF4191 PF13829.6 VBB29215.1 - 0.28 10.5 2.5 0.34 10.2 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2070 PF09843.9 VBB29215.1 - 1.3 7.3 6.9 1.4 7.1 6.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Coilin_N PF15862.5 VBB29216.1 - 0.013 15.3 0.1 0.013 15.3 0.1 3.3 2 1 1 3 3 3 0 Coilin N-terminus DUF3856 PF12968.7 VBB29216.1 - 0.074 13.1 0.2 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) GREB1 PF15782.5 VBB29216.1 - 3.1 4.8 19.8 4.5 4.3 19.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 VBB29216.1 - 4.3 5.5 17.5 5.9 5.0 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.29 VBB29217.1 - 1.3e-38 132.4 0.0 3.1e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB29217.1 - 6.5e-10 38.7 0.0 1.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 VBB29217.1 - 5.6e-06 26.2 0.0 1.6e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 VBB29217.1 - 1.4e-05 25.1 0.1 0.00023 21.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 VBB29217.1 - 1.6e-05 24.2 0.0 3.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 VBB29217.1 - 2e-05 24.8 0.0 5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 VBB29217.1 - 4.5e-05 22.8 0.0 9.2e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 VBB29217.1 - 9.1e-05 22.7 0.2 0.0019 18.4 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB29217.1 - 0.00021 21.7 0.7 0.13 12.6 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Vps4_C PF09336.10 VBB29217.1 - 0.00043 20.2 0.3 0.0022 17.9 0.0 2.4 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 VBB29217.1 - 0.0014 18.4 0.1 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 VBB29217.1 - 0.0026 17.8 0.1 0.0078 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 VBB29217.1 - 0.0027 18.3 0.0 0.009 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 VBB29217.1 - 0.0083 15.5 0.2 0.048 13.0 0.2 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 VBB29217.1 - 0.014 14.8 0.0 6.8 6.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 VBB29217.1 - 0.015 15.7 0.0 0.16 12.4 0.0 2.6 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.6 VBB29217.1 - 0.039 14.1 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PELOTA_1 PF15608.6 VBB29217.1 - 0.054 13.4 0.3 0.19 11.6 0.2 2.0 1 1 0 1 1 1 0 PELOTA RNA binding domain TPR_8 PF13181.6 VBB29217.1 - 0.078 13.2 0.2 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_7 PF12775.7 VBB29217.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region MIT PF04212.18 VBB29217.1 - 0.15 12.2 1.5 0.55 10.3 0.2 2.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain PolyA_pol PF01743.20 VBB29218.1 - 2.1e-22 79.9 0.2 4.4e-21 75.6 0.2 2.5 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 VBB29218.1 - 0.00011 21.9 0.0 0.00036 20.2 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HTH_6 PF01418.17 VBB29218.1 - 0.067 13.2 0.4 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Pkinase PF00069.25 VBB29219.1 - 2.5e-26 92.6 0.7 2.5e-26 92.6 0.7 2.4 2 1 0 2 2 2 1 Protein kinase domain PDZ PF00595.24 VBB29219.1 - 6.1e-16 58.5 0.6 1.4e-15 57.3 0.6 1.7 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 VBB29219.1 - 1.2e-14 54.3 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 VBB29219.1 - 2.5e-06 27.2 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.6 VBB29219.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PDZ_2 PF13180.6 VBB29219.1 - 0.015 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain CHGN PF05679.16 VBB29220.1 - 5.4e-147 490.7 0.0 1.4e-146 489.4 0.0 1.6 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 VBB29220.1 - 1.6e-15 57.2 0.1 2.4e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 VBB29220.1 - 4.6e-10 39.0 0.1 1.4e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 VBB29220.1 - 0.00061 19.3 0.3 0.0054 16.3 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 VBB29220.1 - 0.012 15.2 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Galactosyl_T PF01762.21 VBB29220.1 - 0.028 14.2 0.1 0.47 10.2 0.0 2.5 2 1 0 2 2 2 0 Galactosyltransferase Glycos_transf_2 PF00535.26 VBB29220.1 - 0.036 13.9 2.9 7 6.4 0.4 3.0 2 1 0 2 2 2 0 Glycosyl transferase family 2 GCV_H PF01597.19 VBB29221.1 - 8.4e-33 112.9 0.5 1.1e-32 112.5 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 VBB29221.1 - 0.0068 16.3 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 VBB29221.1 - 0.011 15.6 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme Homeodomain PF00046.29 VBB29222.1 - 8.2e-23 80.0 5.4 1.3e-22 79.4 5.4 1.3 1 0 0 1 1 1 1 Homeodomain Nup_retrotrp_bd PF10599.9 VBB29222.1 - 0.13 12.9 1.8 0.19 12.4 0.4 1.9 2 0 0 2 2 2 0 Retro-transposon transporting motif Peptidase_M14 PF00246.24 VBB29223.1 - 1.4e-15 57.9 0.0 2.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 VBB29223.1 - 2e-10 41.0 0.2 8.3e-10 39.0 0.0 2.1 2 1 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain 4_1_CTD PF05902.13 VBB29224.1 - 7.6e-28 96.7 7.7 7.6e-28 96.7 7.7 4.6 3 2 1 4 4 4 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 VBB29224.1 - 3.5e-19 69.0 0.1 2.3e-18 66.4 0.1 2.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 VBB29224.1 - 3.9e-15 55.5 1.2 3.2e-14 52.6 0.1 3.0 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 VBB29224.1 - 1.7e-11 44.5 0.9 7.8e-11 42.4 0.1 2.7 2 0 0 2 2 2 1 FERM central domain FA PF08736.11 VBB29224.1 - 6.1e-05 23.0 4.2 0.00021 21.3 4.2 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) DUF3439 PF11921.8 VBB29224.1 - 2.9 7.9 12.9 9.8 6.2 12.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PEPCK_GTP PF00821.18 VBB29225.1 - 7.4e-163 541.5 0.8 9.5e-163 541.1 0.8 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 VBB29225.1 - 1.1e-94 316.1 0.0 1.5e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain MutS_V PF00488.21 VBB29228.1 - 4.2e-41 141.1 0.1 7.9e-41 140.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 VBB29228.1 - 4.2e-19 69.5 0.2 1e-18 68.3 0.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 VBB29228.1 - 0.00089 19.6 0.0 0.0024 18.2 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV Sec63 PF02889.16 VBB29228.1 - 0.14 11.3 0.8 0.41 9.8 0.3 1.9 2 0 0 2 2 2 0 Sec63 Brl domain EF-hand_7 PF13499.6 VBB29229.1 - 1.5e-09 38.2 2.5 2.1e-09 37.7 1.8 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB29229.1 - 6.8e-09 35.0 4.6 0.00057 19.6 1.0 3.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 VBB29229.1 - 1.8e-07 30.2 1.1 0.0004 19.7 0.0 2.8 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 VBB29229.1 - 1.6e-05 24.2 0.2 0.002 17.6 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 VBB29229.1 - 0.00026 20.8 3.2 0.002 17.9 0.4 2.6 1 1 1 2 2 2 1 EF-hand domain pair Exo_endo_phos PF03372.23 VBB29230.1 - 4e-14 52.7 0.1 1.6e-13 50.7 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 VBB29230.1 - 0.0067 16.3 1.8 0.012 15.4 0.4 2.3 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase P53 PF00870.18 VBB29231.1 - 1.2e-44 152.5 0.5 1.7e-44 152.0 0.5 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.11 VBB29231.1 - 0.018 14.4 0.0 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 P53 tetramerisation motif SAM_1 PF00536.30 VBB29231.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mnd1 PF03962.15 VBB29232.1 - 1.3e-20 73.5 0.1 2.9e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 VBB29232.1 - 3.7e-20 71.8 1.4 3.7e-20 71.8 1.4 2.2 2 0 0 2 2 2 1 Leucine zipper with capping helix domain FapA PF03961.13 VBB29232.1 - 0.00095 17.9 5.3 0.001 17.8 5.3 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Fmp27_WPPW PF10359.9 VBB29232.1 - 0.0059 15.5 6.7 0.0069 15.3 6.7 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.11 VBB29232.1 - 0.034 13.7 0.7 0.043 13.3 0.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF724 PF05266.14 VBB29232.1 - 0.047 13.5 7.8 0.071 12.9 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LPP PF04728.13 VBB29232.1 - 0.051 14.0 7.4 2.6 8.5 0.4 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper ACT_5 PF13710.6 VBB29232.1 - 0.06 13.2 0.6 0.13 12.1 0.6 1.6 1 0 0 1 1 1 0 ACT domain Tropomyosin_1 PF12718.7 VBB29232.1 - 0.08 13.1 14.0 0.13 12.4 14.0 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF1515 PF07439.11 VBB29232.1 - 0.16 12.0 2.8 0.21 11.6 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Atg14 PF10186.9 VBB29232.1 - 0.16 11.0 5.5 0.21 10.6 5.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 VBB29232.1 - 0.17 11.9 10.3 0.39 10.7 10.3 1.7 1 1 0 1 1 1 0 FlxA-like protein UvrB PF12344.8 VBB29232.1 - 0.18 11.7 1.8 3.5 7.5 0.2 2.6 2 0 0 2 2 2 0 Ultra-violet resistance protein B Seryl_tRNA_N PF02403.22 VBB29232.1 - 0.21 11.8 14.0 0.84 9.9 10.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAM76 PF16046.5 VBB29232.1 - 0.24 10.7 10.6 0.11 11.9 8.5 1.4 2 0 0 2 2 2 0 FAM76 protein DUF812 PF05667.11 VBB29232.1 - 0.24 10.2 11.5 0.32 9.8 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SlyX PF04102.12 VBB29232.1 - 0.25 12.0 7.4 0.72 10.5 0.8 2.5 1 1 1 2 2 2 0 SlyX ABC_tran_CTD PF16326.5 VBB29232.1 - 1.6 9.0 19.7 4.3 7.6 15.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF2205 PF10224.9 VBB29232.1 - 1.7 8.7 13.7 0.67 10.0 5.5 2.4 1 1 1 2 2 2 0 Short coiled-coil protein Spc24 PF08286.11 VBB29232.1 - 1.7 8.9 11.5 7.5 6.8 4.1 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FemAB PF02388.16 VBB29232.1 - 2.1 7.2 7.5 2.8 6.7 7.5 1.2 1 0 0 1 1 1 0 FemAB family GrpE PF01025.19 VBB29232.1 - 2.4 7.8 14.7 1.4e+02 2.0 14.7 2.2 1 1 0 1 1 1 0 GrpE DivIC PF04977.15 VBB29232.1 - 7.6 6.4 14.6 23 4.9 7.3 2.5 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 VBB29232.1 - 8.4 6.6 11.2 7.9 6.6 4.8 2.7 1 1 1 2 2 2 0 Swi5 YabA PF06156.13 VBB29232.1 - 8.9 7.0 7.9 21 5.8 7.9 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Ax_dynein_light PF10211.9 VBB29232.1 - 9 6.2 15.2 6.2 6.7 10.5 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain PhnA_Zn_Ribbon PF08274.12 VBB29233.1 - 0.001 19.0 0.9 0.001 19.0 0.9 1.9 2 0 0 2 2 2 1 PhnA Zinc-Ribbon FdhD-NarQ PF02634.15 VBB29233.1 - 3.1 7.4 5.8 1.9 8.1 0.1 3.0 3 0 0 3 3 3 0 FdhD/NarQ family Pro_isomerase PF00160.21 VBB29235.1 - 7.9e-51 172.5 0.2 8.8e-51 172.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2_4 PF13894.6 VBB29236.1 - 2.9e-09 37.0 59.8 0.0034 18.1 1.5 8.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB29236.1 - 3.8e-06 27.0 63.2 0.025 15.0 2.0 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-Di19 PF05605.12 VBB29236.1 - 2.7e-05 24.4 42.1 0.00074 19.8 3.2 5.4 3 1 2 5 5 4 2 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.12 VBB29236.1 - 0.0044 17.2 4.6 0.0044 17.2 4.6 5.1 4 1 0 5 5 4 1 TFIIH C1-like domain zf-met PF12874.7 VBB29236.1 - 0.021 15.2 0.2 0.021 15.2 0.2 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB29236.1 - 0.023 15.0 0.9 0.023 15.0 0.9 6.7 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding Hint_2 PF13403.6 VBB29236.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Hint domain zf-C2H2_12 PF18658.1 VBB29236.1 - 0.11 12.1 9.9 1.6 8.3 0.9 4.1 4 0 0 4 4 4 0 Zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 VBB29236.1 - 0.15 12.7 24.3 0.52 11.0 0.2 4.8 3 2 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 VBB29236.1 - 0.5 8.8 0.0 0.5 8.8 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 VBB29236.1 - 0.96 9.3 12.8 3.1 7.7 0.1 4.4 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 VBB29236.1 - 1.1 9.1 21.0 0.74 9.6 0.2 5.4 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 VBB29236.1 - 2.7 8.4 25.6 0.026 14.8 7.0 3.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 VBB29236.1 - 3.5 8.2 53.4 0.23 12.0 1.0 7.8 8 0 0 8 8 7 0 Zinc-finger double domain Zn-C2H2_12 PF18112.1 VBB29236.1 - 3.6 8.1 13.4 0.76 10.3 0.2 4.3 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain DUF4428 PF14471.6 VBB29236.1 - 5.1 7.1 11.8 0.09 12.7 2.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2_2 PF12756.7 VBB29236.1 - 5.9 7.3 39.1 1.2 9.5 0.2 6.0 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) MBOAT PF03062.19 VBB29237.1 - 3.5e-06 26.6 6.8 3.5e-06 26.6 6.8 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family zf-C2H2 PF00096.26 VBB29239.1 - 2e-14 53.1 22.8 5.1e-06 26.6 1.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB29239.1 - 8e-12 44.9 20.1 0.0008 20.1 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB29239.1 - 2.7e-10 40.2 20.7 1e-06 28.9 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 VBB29239.1 - 2.3e-07 30.9 14.1 0.012 15.9 2.9 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB29239.1 - 1.1e-06 28.4 17.1 0.00011 22.1 0.4 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 VBB29239.1 - 0.0002 21.7 16.1 0.26 11.7 0.0 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-CRD PF17979.1 VBB29239.1 - 0.003 17.7 10.1 0.041 14.0 6.0 2.4 1 1 1 2 2 2 1 Cysteine rich domain with multizinc binding regions GAGA PF09237.11 VBB29239.1 - 0.003 17.3 2.4 0.77 9.6 0.2 2.8 1 1 1 2 2 2 2 GAGA factor zf-AN1 PF01428.16 VBB29239.1 - 0.01 15.9 15.2 0.67 10.2 4.0 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger XPA_N PF01286.18 VBB29239.1 - 0.034 14.2 7.5 2.8 8.1 0.4 3.4 3 0 0 3 3 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 VBB29239.1 - 0.038 14.1 1.8 0.038 14.1 1.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain BolA PF01722.18 VBB29239.1 - 0.069 13.4 0.3 3 8.2 0.3 2.4 1 1 0 1 1 1 0 BolA-like protein C1_4 PF07975.12 VBB29239.1 - 0.35 11.1 13.5 2.6 8.4 0.6 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 VBB29239.1 - 0.54 10.2 13.0 0.79 9.7 0.5 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 VBB29239.1 - 1.8 8.2 9.0 11 5.7 1.1 3.1 1 1 2 3 3 3 0 MYST family zinc finger domain LIM PF00412.22 VBB29239.1 - 6.2 7.1 11.3 8.7 6.7 0.4 3.0 1 1 0 2 2 2 0 LIM domain DEAD PF00270.29 VBB29240.1 - 2.8e-21 76.1 0.1 4.4e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB29240.1 - 1.9e-19 70.1 0.0 2.9e-18 66.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 VBB29240.1 - 1e-08 35.8 2.2 1e-08 35.8 2.2 2.3 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 VBB29240.1 - 1.1e-06 28.8 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 VBB29240.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain ArsA_ATPase PF02374.15 VBB29240.1 - 0.03 13.5 0.2 0.059 12.5 0.1 1.4 1 1 0 1 1 1 0 Anion-transporting ATPase Syntaxin-18_N PF10496.9 VBB29240.1 - 0.073 13.3 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus GPS2_interact PF15784.5 VBB29240.1 - 0.59 10.6 6.4 0.24 11.9 2.8 2.0 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sec1 PF00995.23 VBB29241.1 - 1.7e-31 110.1 0.0 3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.25 VBB29242.1 - 9.5e-62 208.7 0.0 2.1e-61 207.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29242.1 - 5.7e-34 117.6 0.0 1.6e-33 116.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_3 PF13920.6 VBB29245.1 - 1.9e-09 37.2 12.6 3.8e-09 36.3 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Neur_chan_memb PF02932.16 VBB29247.1 - 6.9e-15 55.8 1.0 1.8e-14 54.4 0.1 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region ABC2_membrane_3 PF12698.7 VBB29247.1 - 0.012 14.7 0.3 0.014 14.5 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 7tm_1 PF00001.21 VBB29247.1 - 0.033 13.5 0.5 0.045 13.1 0.5 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sarcoglycan_2 PF05510.13 VBB29247.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DIX PF00778.17 VBB29248.1 - 5.9e-20 70.9 0.4 1.5e-19 69.6 0.4 1.7 1 0 0 1 1 1 1 DIX domain DEP PF00610.21 VBB29248.1 - 3.7e-16 59.0 0.0 9.1e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.24 VBB29248.1 - 2.3e-12 47.1 0.1 5.4e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 VBB29248.1 - 5.1e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Ras family PDZ_6 PF17820.1 VBB29248.1 - 5.5e-05 22.9 0.1 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Roc PF08477.13 VBB29248.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PDZ_2 PF13180.6 VBB29248.1 - 0.038 14.3 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 PDZ domain Dishevelled PF02377.15 VBB29248.1 - 0.28 11.6 2.2 0.38 11.2 0.6 2.1 2 0 0 2 2 2 0 Dishevelled specific domain Cas_Csy1 PF09611.10 VBB29249.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) V-ATPase_H_C PF11698.8 VBB29249.1 - 0.034 14.3 3.5 30 4.7 0.0 3.8 3 0 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 VBB29249.1 - 0.061 13.4 0.0 3.7 7.7 0.0 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 VBB29249.1 - 0.14 12.1 15.1 0.35 10.8 1.2 4.8 2 2 0 4 4 4 0 Domain of unknown function (DUF3361) Vac14_Fab1_bd PF12755.7 VBB29249.1 - 4.4 8.0 7.2 1.1 9.9 0.3 3.4 3 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region AA_permease_2 PF13520.6 VBB29250.1 - 2.1e-45 155.4 46.7 2.1e-45 155.4 46.7 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 VBB29250.1 - 5.4e-34 117.6 44.5 5.4e-34 117.6 44.5 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 VBB29250.1 - 1.7e-19 69.6 10.0 1.7e-19 69.6 10.0 4.2 4 1 0 4 4 4 1 C-terminus of AA_permease RRM_1 PF00076.22 VBB29251.1 - 4.1e-46 154.7 0.2 1.1e-19 69.9 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB29251.1 - 0.00032 20.8 0.0 1.5 9.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 VBB29251.1 - 0.0014 18.6 0.1 4.2 7.5 0.0 3.6 3 0 0 3 3 3 2 RNA binding domain PHM7_cyt PF14703.6 VBB29251.1 - 0.27 11.4 1.4 41 4.3 0.2 3.3 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter KCNQ_channel PF03520.14 VBB29252.1 - 6.8e-33 114.1 8.0 2e-30 106.1 8.0 2.5 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel SNF2_N PF00176.23 VBB29253.1 - 8.2e-62 208.9 0.0 1.5e-61 208.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB29253.1 - 4.5e-21 75.3 0.1 1.8e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIF_alpha PF05793.12 VBB29253.1 - 0.023 13.3 32.9 0.11 11.0 13.4 3.1 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PCI PF01399.27 VBB29254.1 - 2.2e-09 37.8 0.5 8e-09 36.0 0.1 2.1 2 0 0 2 2 2 1 PCI domain tRNA-synt_2 PF00152.20 VBB29255.1 - 2e-77 260.4 0.0 3.2e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 VBB29255.1 - 2e-13 50.1 0.0 1.4e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 VBB29255.1 - 1.7e-09 37.5 0.1 7.2e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Alpha_kinase PF02816.18 VBB29255.1 - 0.043 13.9 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Alpha-kinase family Lipocalin_2 PF08212.12 VBB29255.1 - 0.11 12.4 0.7 0.22 11.4 0.7 1.4 1 0 0 1 1 1 0 Lipocalin-like domain ATP-synt_E PF05680.12 VBB29255.1 - 1.9 8.9 11.9 0.19 12.1 7.4 1.6 2 0 0 2 2 2 0 ATP synthase E chain NUDIX PF00293.28 VBB29256.1 - 3.3e-14 53.0 0.0 5.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain GpcrRhopsn4 PF10192.9 VBB29258.1 - 1.8e-38 132.4 25.8 1.6e-32 113.0 15.3 2.8 2 1 1 3 3 3 2 Rhodopsin-like GPCR transmembrane domain CAP PF00188.26 VBB29258.1 - 1.6e-18 67.7 0.1 3.3e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Bromo_TP PF07524.13 VBB29259.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 VBB29259.1 - 1.6e-08 34.3 8.0 8e-07 28.9 8.2 2.7 1 1 1 2 2 2 2 PHD-finger TFIID-31kDa PF02291.15 VBB29259.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 VBB29259.1 - 0.0046 17.3 0.0 0.018 15.4 0.0 2.0 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 VBB29259.1 - 0.018 15.1 0.0 0.097 12.8 0.0 2.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP_like PF17027.5 VBB29259.1 - 0.03 14.5 0.2 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Histone-fold protein PHD_2 PF13831.6 VBB29259.1 - 0.12 11.9 7.5 0.03 13.9 2.7 2.2 2 0 0 2 2 2 0 PHD-finger zf-CDGSH PF09360.10 VBB29260.1 - 0.27 11.5 3.6 0.76 10.0 3.4 1.9 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type Ion_trans_2 PF07885.16 VBB29262.1 - 1.3e-35 121.1 19.1 1.1e-17 63.8 10.0 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 VBB29262.1 - 0.0037 16.5 13.1 0.31 10.2 8.8 2.4 1 1 1 2 2 2 2 Ion transport protein IRK PF01007.20 VBB29262.1 - 0.011 15.5 2.6 1.2 9.0 0.8 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Lig_chan PF00060.26 VBB29262.1 - 0.063 13.1 6.0 0.2 11.5 0.1 3.1 2 1 0 2 2 2 0 Ligand-gated ion channel Laps PF10169.9 VBB29262.1 - 0.83 10.2 3.6 1.5 9.4 3.6 1.3 1 0 0 1 1 1 0 Learning-associated protein PIRT PF15099.6 VBB29262.1 - 8.8 5.9 10.1 7 6.2 0.5 3.2 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family Methyltransf_16 PF10294.9 VBB29264.1 - 7.6e-16 58.3 0.1 1.2e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase BcrAD_BadFG PF01869.20 VBB29264.1 - 1.9e-13 50.5 0.0 2.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Arv1 PF04161.13 VBB29265.1 - 3.6e-25 89.4 1.4 4.8e-25 89.0 1.4 1.2 1 0 0 1 1 1 1 Arv1-like family Elf1 PF05129.13 VBB29265.1 - 0.009 16.0 0.6 0.017 15.2 0.6 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Androgen_recep PF02166.16 VBB29265.1 - 0.089 11.6 2.5 0.045 12.6 0.8 1.4 2 0 0 2 2 2 0 Androgen receptor BHD_3 PF10405.9 VBB29266.1 - 7.2e-25 87.2 0.0 1.8e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 VBB29266.1 - 8.1e-15 54.4 0.2 2.4e-14 52.9 0.2 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 VBB29266.1 - 1.5e-14 53.9 0.1 1.5e-14 53.9 0.1 2.6 3 1 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 VBB29266.1 - 2.2e-11 44.6 0.4 2.2e-11 44.6 0.4 3.4 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 I-set PF07679.16 VBB29266.1 - 1e-08 35.1 2.2 0.0026 17.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB29266.1 - 0.00055 20.5 0.0 0.29 11.7 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Big_3 PF07523.12 VBB29266.1 - 0.015 15.6 1.4 2.7 8.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3979 PF13141.6 VBB29266.1 - 0.026 14.8 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) 2OG-FeII_Oxy_2 PF13532.6 VBB29267.1 - 7.2e-38 130.7 0.0 1e-37 130.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCNA_C PF02747.15 VBB29268.1 - 8.8e-45 152.0 0.0 1.5e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 VBB29268.1 - 2.9e-44 149.8 4.2 2.9e-44 149.8 4.2 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 VBB29268.1 - 1.1e-11 44.3 1.1 2e-10 40.2 1.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 VBB29268.1 - 0.00011 21.5 0.1 0.00036 19.7 0.1 1.8 1 1 1 2 2 2 1 Hus1-like protein Rad9 PF04139.13 VBB29268.1 - 0.0022 17.5 0.3 0.0027 17.2 0.3 1.3 1 1 0 1 1 1 1 Rad9 p25-alpha PF05517.12 VBB29268.1 - 0.06 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 p25-alpha Baculo_11_kDa PF06143.11 VBB29269.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family CDP-OH_P_transf PF01066.21 VBB29270.1 - 0.099 13.4 0.1 0.099 13.4 0.1 3.4 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase V-set_CD47 PF08204.11 VBB29270.1 - 0.17 11.8 2.6 0.62 10.1 1.0 2.2 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Collagen PF01391.18 VBB29272.1 - 9.6e-10 38.1 27.2 1.7e-09 37.3 27.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pro_isomerase PF00160.21 VBB29275.1 - 2.9e-38 131.6 0.0 4.7e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 VBB29275.1 - 2e-10 40.3 0.1 4.6e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta-Casp PF10996.8 VBB29276.1 - 1.2e-23 83.5 0.0 2.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 VBB29276.1 - 6.9e-15 55.0 0.0 1.2e-08 34.7 0.0 2.6 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 VBB29276.1 - 1.6e-14 53.5 0.0 3.9e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 VBB29276.1 - 2.2e-11 44.2 2.3 1.5e-10 41.4 2.3 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB29276.1 - 9.9e-09 35.0 0.4 5.1e-07 29.4 0.1 2.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 VBB29276.1 - 0.00067 19.6 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Chromadorea_ALT PF05535.12 VBB29277.1 - 6.6e-06 26.2 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Chromadorea ALT protein PHD_2 PF13831.6 VBB29277.1 - 0.054 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 PHD-finger CD36 PF01130.21 VBB29278.1 - 4e-55 187.2 3.3 5.3e-55 186.8 3.3 1.0 1 0 0 1 1 1 1 CD36 family Sushi PF00084.20 VBB29279.1 - 8.7e-21 74.3 14.8 3.4e-08 34.0 1.1 3.2 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) cEGF PF12662.7 VBB29279.1 - 4.2 7.4 13.8 1.2 9.2 0.4 4.1 4 2 0 4 4 4 0 Complement Clr-like EGF-like KIAA1328 PF15369.6 VBB29280.1 - 0.6 9.9 3.4 1 9.1 3.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 UEV PF05743.13 VBB29281.1 - 2.4e-36 124.3 0.0 4.4e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 VBB29281.1 - 1.7e-22 79.1 0.1 3.9e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Vps23 core domain Vps54_N PF10475.9 VBB29281.1 - 0.004 16.5 1.9 0.0062 15.9 1.9 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF1394 PF07159.12 VBB29281.1 - 0.013 14.8 0.2 0.019 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) GAS PF13851.6 VBB29281.1 - 0.057 12.8 3.1 0.089 12.1 1.6 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 VBB29281.1 - 0.16 10.6 0.5 0.23 10.0 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C2H2_4 PF13894.6 VBB29282.1 - 0.066 14.1 8.6 1.4 10.0 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.14 VBB29282.1 - 0.068 13.1 5.7 3.6 7.6 0.2 2.5 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.26 VBB29282.1 - 0.35 11.4 6.5 5.1 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DnaJ PF00226.31 VBB29283.1 - 9.7e-18 64.1 1.2 3.5e-17 62.3 1.2 2.0 1 0 0 1 1 1 1 DnaJ domain COX14 PF14880.6 VBB29283.1 - 0.19 11.6 6.0 6.8 6.6 0.0 3.7 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Methyltransf_23 PF13489.6 VBB29284.1 - 1e-13 51.5 0.0 2e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB29284.1 - 1.2e-13 51.5 0.2 2.4e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB29284.1 - 1.1e-10 41.5 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB29284.1 - 3e-10 40.7 0.3 1e-09 39.0 0.2 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB29284.1 - 2.1e-07 31.6 0.0 4.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 VBB29284.1 - 2.1e-05 24.0 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 VBB29284.1 - 6e-05 22.6 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 VBB29284.1 - 0.00012 21.7 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 VBB29284.1 - 0.0018 17.9 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 VBB29284.1 - 0.024 14.6 0.0 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 VBB29284.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Complex1_LYR PF05347.15 VBB29284.1 - 0.1 12.6 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) PCMT PF01135.19 VBB29284.1 - 0.12 12.1 0.1 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDI PF00996.18 VBB29285.1 - 1.1e-202 673.4 2.4 8.6e-202 670.4 2.4 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor Acetyltransf_7 PF13508.7 VBB29287.1 - 0.00024 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 VBB29287.1 - 0.0024 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB29287.1 - 0.05 13.8 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB29287.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3657 PF12394.8 VBB29287.1 - 0.43 11.2 0.0 0.43 11.2 0.0 2.8 3 2 0 3 3 3 0 Protein FAM135 Glyco_hydro_38N PF01074.22 VBB29288.1 - 5.6e-90 301.6 5.5 5.6e-90 301.6 5.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 VBB29288.1 - 1e-26 94.3 0.0 6.2e-26 91.8 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 VBB29288.1 - 2.3e-21 75.8 1.6 4.4e-21 74.8 0.1 2.4 3 0 0 3 3 3 1 Alpha mannosidase middle domain Ly49 PF08391.10 VBB29288.1 - 0.088 13.2 1.3 0.25 11.7 1.3 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region SKA1 PF07160.12 VBB29288.1 - 8 6.2 8.7 17 5.2 8.7 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Pkinase PF00069.25 VBB29289.1 - 2.2e-59 201.0 0.0 6.2e-59 199.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29289.1 - 1.4e-31 109.7 0.4 3e-22 79.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 VBB29289.1 - 0.00019 22.1 0.2 0.00052 20.7 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 VBB29289.1 - 0.0002 20.4 0.3 0.0003 19.9 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 VBB29289.1 - 0.00032 20.1 1.1 0.0078 15.6 0.2 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 VBB29289.1 - 0.0015 17.9 0.4 0.0061 15.9 0.0 2.1 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB29289.1 - 0.0075 16.2 1.0 0.16 11.9 0.2 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 VBB29289.1 - 0.039 12.9 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 VBB29289.1 - 0.054 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EGF PF00008.27 VBB29292.1 - 2.6e-26 91.6 117.0 9.6e-06 25.8 6.4 9.5 10 0 0 10 10 10 7 EGF-like domain LRR_8 PF13855.6 VBB29292.1 - 2.9e-24 84.6 14.9 1e-15 57.2 4.4 4.3 3 1 1 4 4 4 3 Leucine rich repeat Laminin_G_1 PF00054.23 VBB29292.1 - 3e-19 69.5 0.0 5.8e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 VBB29292.1 - 4.9e-18 65.9 0.0 7.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 VBB29292.1 - 1.9e-14 53.7 92.5 7e-06 26.5 2.9 10.2 11 0 0 11 11 11 7 Human growth factor-like EGF LRRNT PF01462.18 VBB29292.1 - 8.2e-10 38.1 1.9 8.2e-10 38.1 1.9 7.0 10 0 0 10 10 10 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 VBB29292.1 - 8.7e-07 29.2 16.9 0.00023 21.5 0.7 4.4 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB29292.1 - 5.3e-06 26.1 1.5 1e-05 25.1 1.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeat EGF_3 PF12947.7 VBB29292.1 - 0.0062 16.7 2.1 0.0062 16.7 2.1 10.0 9 1 1 10 10 10 6 EGF domain QVR PF17064.5 VBB29293.1 - 6.8e-08 32.6 6.8 8.3e-08 32.4 3.6 2.0 2 0 0 2 2 2 1 Sleepless protein Ig_3 PF13927.6 VBB29295.1 - 1.5e-61 205.0 0.9 1.3e-07 32.1 0.1 9.6 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.6 VBB29295.1 - 7.1e-44 148.0 2.8 4.4e-05 23.7 0.0 9.5 9 0 0 9 9 9 9 Immunoglobulin domain I-set PF07679.16 VBB29295.1 - 1.7e-41 140.2 0.0 4.1e-05 23.6 0.0 8.8 9 0 0 9 9 9 8 Immunoglobulin I-set domain ig PF00047.25 VBB29295.1 - 4e-41 139.1 4.6 1.7e-05 24.9 0.1 8.6 8 0 0 8 8 8 8 Immunoglobulin domain C2-set_2 PF08205.12 VBB29295.1 - 5.9e-38 128.8 0.5 6.5e-10 39.0 0.0 7.0 6 0 0 6 6 6 5 CD80-like C2-set immunoglobulin domain V-set PF07686.17 VBB29295.1 - 9.9e-12 45.0 7.1 8e-05 22.8 0.0 8.8 8 2 0 8 8 8 1 Immunoglobulin V-set domain fn3 PF00041.21 VBB29295.1 - 1.1e-08 35.3 0.1 2.7e-07 30.8 0.0 3.0 2 0 0 2 2 2 1 Fibronectin type III domain C1-set PF07654.15 VBB29295.1 - 2.7e-08 34.1 2.6 0.046 14.1 0.0 5.8 6 0 0 6 6 6 3 Immunoglobulin C1-set domain Ig_4 PF16680.5 VBB29295.1 - 0.0096 16.2 0.5 60 4.0 0.0 5.1 6 0 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain DUF851 PF05867.11 VBB29296.1 - 4.9e-10 39.3 0.9 4.9e-10 39.3 0.9 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF851) WD40 PF00400.32 VBB29297.1 - 7.6e-40 134.2 17.5 1.3e-06 29.1 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29297.1 - 1.2e-13 51.2 0.0 0.0085 16.4 0.1 5.4 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB29297.1 - 0.0011 18.8 0.0 2.7 7.8 0.0 2.8 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 VBB29297.1 - 0.0014 18.0 0.0 0.04 13.3 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 VBB29297.1 - 0.16 10.9 0.3 53 2.6 0.0 3.5 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FXa_inhibition PF14670.6 VBB29297.1 - 0.32 11.3 3.9 6.1 7.2 0.4 3.2 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site HLH PF00010.26 VBB29298.1 - 2e-16 59.7 4.3 2e-16 59.7 4.3 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TH1 PF04858.13 VBB29300.1 - 2.4e-25 89.2 0.7 2.6e-25 89.1 0.7 1.1 1 0 0 1 1 1 1 TH1 protein Med12-LCEWAV PF12145.8 VBB29301.1 - 8.4e-54 183.2 12.3 1.1e-52 179.5 3.1 3.9 2 1 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 VBB29301.1 - 4.4e-12 46.1 0.1 1.7e-11 44.2 0.1 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Hydrolase_4 PF12146.8 VBB29302.1 - 2.6e-11 43.3 0.0 2.8e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 VBB29302.1 - 2.9e-10 40.2 0.0 0.00084 19.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 VBB29302.1 - 2.1e-06 26.9 0.0 3.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 VBB29302.1 - 1.5e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 VBB29302.1 - 2e-05 25.3 0.0 9.5e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 VBB29302.1 - 0.0026 17.6 0.1 0.57 10.0 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase LIP PF03583.14 VBB29302.1 - 0.008 15.5 0.2 0.42 9.9 0.1 2.2 2 0 0 2 2 2 1 Secretory lipase FSH1 PF03959.13 VBB29302.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COesterase PF00135.28 VBB29305.1 - 3.9e-112 375.7 0.1 1.3e-111 374.0 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB29305.1 - 6.9e-10 39.1 0.7 1e-08 35.3 0.7 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 VBB29305.1 - 0.042 13.3 0.2 0.66 9.4 0.1 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family QVR PF17064.5 VBB29306.1 - 0.44 10.8 9.2 0.5 10.6 7.4 2.0 1 1 1 2 2 2 0 Sleepless protein E2F_TDP PF02319.20 VBB29307.1 - 2.8e-21 75.4 0.1 5.6e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 VBB29307.1 - 9.1e-18 64.4 0.4 9.1e-18 64.4 0.4 2.2 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain Cytochrom_B562 PF07361.11 VBB29307.1 - 0.15 12.7 0.1 0.39 11.4 0.1 1.7 1 0 0 1 1 1 0 Cytochrome b562 MADF_DNA_bdg PF10545.9 VBB29309.1 - 3.2e-16 59.4 1.5 6.3e-16 58.5 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Lin-8 PF03353.15 VBB29309.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Zw10 PF06248.13 VBB29310.1 - 9.9e-58 196.0 10.2 1.2e-57 195.7 10.2 1.0 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 EAP30 PF04157.16 VBB29310.1 - 0.015 14.6 0.0 0.31 10.3 0.0 2.7 3 1 1 4 4 4 0 EAP30/Vps36 family DNA_repr_REX1B PF14966.6 VBB29310.1 - 0.035 14.8 1.0 6.3 7.5 0.1 2.9 2 0 0 2 2 2 0 DNA repair REX1-B PepX_N PF09168.10 VBB29310.1 - 0.14 12.5 7.9 7.4 7.0 0.3 3.4 3 0 0 3 3 3 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Phage_sheath_1C PF17482.2 VBB29310.1 - 0.3 11.1 3.9 12 6.0 0.5 3.6 3 1 0 3 3 3 0 Phage tail sheath C-terminal domain Baculo_PEP_C PF04513.12 VBB29310.1 - 0.33 11.0 12.7 0.098 12.7 2.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 VBB29310.1 - 3.4 7.8 6.8 0.9 9.6 0.2 3.1 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4011 PF13195.6 VBB29310.1 - 9.3 6.1 8.2 14 5.6 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4011) Reticulon PF02453.17 VBB29311.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Reticulon ISK_Channel PF02060.15 VBB29313.1 - 0.062 13.0 0.4 0.071 12.8 0.4 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel HALZ PF02183.18 VBB29313.1 - 0.095 12.9 0.1 2.4 8.5 0.0 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper PTR2 PF00854.21 VBB29314.1 - 2.7e-113 378.8 12.6 2.4e-101 339.4 6.6 2.2 2 0 0 2 2 2 2 POT family H_PPase PF03030.16 VBB29314.1 - 0.0033 16.1 1.0 0.0072 15.0 1.0 1.5 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Rotavirus_VP1 PF12289.8 VBB29314.1 - 0.036 13.1 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Rotavirus VP1 C-terminal domain SNARE_assoc PF09335.11 VBB29315.1 - 5.7e-17 62.3 4.3 5.7e-17 62.3 4.3 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein HCO3_cotransp PF00955.21 VBB29316.1 - 1.2e-28 100.2 3.5 1.2e-28 100.2 3.5 1.6 2 0 0 2 2 2 1 HCO3- transporter family DUF2798 PF11391.8 VBB29316.1 - 0.15 12.1 2.4 0.3 11.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) DUF4181 PF13789.6 VBB29316.1 - 0.29 11.4 3.5 0.25 11.6 1.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) IRS PF02174.17 VBB29318.1 - 0.00037 20.3 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 PTB domain (IRS-1 type) PH PF00169.29 VBB29318.1 - 0.0026 18.3 0.0 0.0092 16.5 0.0 1.9 1 0 0 1 1 1 1 PH domain RRN3 PF05327.11 VBB29319.1 - 0.013 14.0 3.9 0.017 13.7 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3498 PF12004.8 VBB29319.1 - 0.017 14.3 1.1 0.017 14.3 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) Exonuc_VII_L PF02601.15 VBB29319.1 - 0.039 13.5 3.8 0.05 13.2 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TolA_bind_tri PF16331.5 VBB29319.1 - 0.074 13.1 4.1 0.079 13.0 0.7 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation NPV_P10 PF05531.12 VBB29319.1 - 0.18 12.3 4.0 15 6.2 2.4 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec8_exocyst PF04048.14 VBB29319.1 - 0.31 10.9 10.5 0.21 11.5 0.9 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain FapA PF03961.13 VBB29319.1 - 0.62 8.6 11.2 0.31 9.6 6.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A HSBP1 PF06825.12 VBB29319.1 - 2 8.4 9.8 4.6 7.2 1.0 3.4 2 2 1 3 3 3 0 Heat shock factor binding protein 1 Rx_N PF18052.1 VBB29319.1 - 2.4 8.5 8.5 4.8 7.5 3.2 2.4 1 1 0 2 2 2 0 Rx N-terminal domain V-SNARE_C PF12352.8 VBB29320.1 - 1.3e-05 25.4 11.3 0.00013 22.2 4.5 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 VBB29320.1 - 0.0022 17.9 9.8 0.19 11.6 1.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) SSB PF00436.25 VBB29320.1 - 0.0035 17.4 0.0 0.016 15.2 0.0 2.1 1 1 0 1 1 1 1 Single-strand binding protein family DUF745 PF05335.13 VBB29320.1 - 0.045 13.5 9.6 0.057 13.1 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF745) tRNA_anti-codon PF01336.25 VBB29320.1 - 0.062 13.3 0.2 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain LPP PF04728.13 VBB29320.1 - 0.095 13.1 2.2 0.26 11.7 2.2 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper 5_3_exonuc PF01367.20 VBB29320.1 - 0.14 12.7 3.4 1.3 9.7 0.1 3.3 3 1 1 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold DUF1664 PF07889.12 VBB29320.1 - 0.26 11.3 8.1 1.9 8.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 VBB29320.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3053 PF11254.8 VBB29320.1 - 2.5 7.6 7.9 0.31 10.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) SSB PF00436.25 VBB29321.1 - 1.9e-08 34.3 0.1 3.1e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 VBB29321.1 - 0.1 12.6 0.7 0.33 11.0 0.2 1.9 1 1 0 2 2 2 0 OB-fold nucleic acid binding domain Epimerase PF01370.21 VBB29323.1 - 1.6e-52 178.4 0.0 2.2e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 VBB29323.1 - 1.5e-14 54.1 0.4 8.8e-14 51.6 0.0 1.9 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 VBB29323.1 - 2e-07 30.4 0.0 3.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 VBB29323.1 - 0.00039 19.6 1.5 0.021 14.0 0.0 2.5 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 VBB29323.1 - 0.001 18.1 0.3 0.01 14.9 0.3 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UQ_con PF00179.26 VBB29324.1 - 2.4e-42 143.9 0.1 2.7e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 VBB29324.1 - 0.0012 19.1 0.1 0.0018 18.5 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 VBB29324.1 - 0.0032 17.3 0.2 0.0063 16.4 0.2 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 VBB29324.1 - 0.022 14.4 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B HV_small_capsid PF17086.5 VBB29324.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Small capsid protein of Herpesviridae MCM PF00493.23 VBB29325.1 - 2.8e-84 281.7 0.8 4.4e-83 277.8 0.8 2.1 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 VBB29325.1 - 3e-36 124.1 0.4 4.2e-35 120.3 0.3 2.3 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 VBB29325.1 - 3.3e-24 85.1 0.2 7.3e-24 84.0 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 VBB29325.1 - 7e-14 52.3 1.2 7e-14 52.3 1.2 2.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 VBB29325.1 - 0.0034 16.8 0.0 0.092 12.1 0.0 2.7 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB29325.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 VBB29325.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 VBB29325.1 - 0.07 12.8 0.0 0.41 10.3 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain adh_short PF00106.25 VBB29326.1 - 7.4e-37 126.7 0.1 1.2e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB29326.1 - 5.8e-33 114.4 0.1 1.7e-32 112.9 0.1 1.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 VBB29326.1 - 3.7e-15 56.2 0.0 7.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 VBB29326.1 - 1.3e-06 28.5 0.1 2.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 KR domain L_protein_N PF15518.6 VBB29326.1 - 0.047 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 L protein N-terminus Alkyl_sulf_C PF14864.6 VBB29326.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal CBFD_NFYB_HMF PF00808.23 VBB29327.1 - 7.1e-12 45.4 0.0 1.7e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB29327.1 - 1.4e-07 31.9 0.3 2.7e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pup PF05639.11 VBB29327.1 - 0.089 13.7 0.7 0.089 13.7 0.7 2.2 1 1 1 2 2 2 0 Pup-like protein DOMON PF03351.17 VBB29329.1 - 8.2e-10 39.0 0.0 1.3e-08 35.1 0.0 3.0 3 0 0 3 3 3 1 DOMON domain EGF_2 PF07974.13 VBB29329.1 - 1.6e-05 25.2 20.7 0.0013 19.1 7.1 2.6 2 0 0 2 2 2 2 EGF-like domain I-EGF_1 PF18372.1 VBB29329.1 - 0.0093 16.0 1.2 0.0093 16.0 1.2 2.0 2 0 0 2 2 2 1 Integrin beta epidermal growth factor like domain 1 Laminin_EGF PF00053.24 VBB29329.1 - 1.2 9.3 16.9 2.3 8.4 6.6 2.6 1 1 1 2 2 2 0 Laminin EGF domain EGF PF00008.27 VBB29329.1 - 3.1 8.2 17.2 0.032 14.5 4.8 2.8 3 0 0 3 3 3 0 EGF-like domain zf-MYND PF01753.18 VBB29331.1 - 0.41 10.8 4.4 1.2 9.2 4.4 1.7 1 1 0 1 1 1 0 MYND finger Pkinase PF00069.25 VBB29332.1 - 2.1e-42 145.4 0.1 6.5e-42 143.7 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29332.1 - 9.5e-28 97.2 0.0 1.6e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Polo_box_3 PF18544.1 VBB29332.1 - 1.2e-27 96.4 0.1 3.3e-27 95.0 0.1 1.8 1 0 0 1 1 1 1 Polo box domain Pkinase_fungal PF17667.1 VBB29332.1 - 3.7e-05 22.7 0.0 7.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB29332.1 - 0.00044 19.7 0.1 0.0017 17.8 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Polo_box_2 PF18531.1 VBB29332.1 - 0.042 14.0 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 Polo box domain Plk4_PB2 PF18409.1 VBB29332.1 - 0.1 13.3 0.0 0.42 11.3 0.0 2.1 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Cript PF10235.9 VBB29332.1 - 0.49 11.0 4.7 0.19 12.3 0.6 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Homeodomain PF00046.29 VBB29333.1 - 5.1e-22 77.5 4.2 7.8e-22 76.9 4.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB29333.1 - 0.021 14.7 0.1 0.055 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 VBB29333.1 - 0.17 11.4 1.5 0.37 10.3 1.5 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Piwi PF02171.17 VBB29334.1 - 8.3e-63 212.4 0.0 1.3e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 VBB29334.1 - 2.5e-10 40.3 0.2 1.2e-09 38.1 0.0 2.2 2 1 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 VBB29334.1 - 8.6e-05 22.7 0.1 0.00026 21.2 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute T_hemolysin PF12261.8 VBB29334.1 - 0.23 11.2 0.7 3.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Thermostable hemolysin Kri1_C PF12936.7 VBB29335.1 - 6.3e-26 90.4 3.1 6.3e-26 90.4 3.1 4.3 3 1 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 VBB29335.1 - 2.7e-20 72.8 9.6 2.7e-20 72.8 9.6 6.0 5 2 1 6 6 6 1 KRI1-like family DUF2981 PF11200.8 VBB29335.1 - 1.5 8.5 3.4 3.8 7.2 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) BSMAP PF12280.8 VBB29336.1 - 1.5e-09 38.3 5.3 1.5e-09 38.3 5.3 3.1 1 1 1 2 2 2 2 Brain specific membrane anchored protein DUF5481 PF17578.2 VBB29336.1 - 0.059 13.8 0.7 0.11 12.9 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5481) zf-RING_2 PF13639.6 VBB29337.1 - 6.4e-10 39.2 9.7 6.4e-10 39.2 9.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB29337.1 - 6.5e-09 35.5 8.2 1.8e-08 34.1 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB29337.1 - 1.4e-08 34.8 6.9 1.4e-08 34.8 6.9 2.8 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB29337.1 - 1.7e-06 27.8 7.4 1.7e-06 27.8 7.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB29337.1 - 6.3e-06 26.1 1.7 6.3e-06 26.1 1.7 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 VBB29337.1 - 1.4e-05 24.7 7.2 2e-05 24.2 4.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 VBB29337.1 - 6.1e-05 23.0 8.5 0.0002 21.3 3.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 VBB29337.1 - 7.3e-05 22.5 7.9 7.3e-05 22.5 7.9 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB29337.1 - 0.00014 21.7 8.4 0.00014 21.7 8.4 2.3 2 1 1 3 3 3 1 zinc-RING finger domain Fib_alpha PF08702.10 VBB29337.1 - 0.00069 19.8 13.5 0.056 13.6 1.2 2.2 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Zn_ribbon_17 PF17120.5 VBB29337.1 - 0.0064 16.1 7.1 0.0064 16.1 7.1 2.5 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 VBB29337.1 - 0.011 15.8 6.2 0.011 15.8 6.2 2.2 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 VBB29337.1 - 0.013 15.4 5.2 0.013 15.4 5.2 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 VBB29337.1 - 0.06 13.2 1.6 0.06 13.2 1.6 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit SlyX PF04102.12 VBB29337.1 - 0.06 14.0 2.0 0.06 14.0 2.0 2.9 3 1 1 4 4 4 0 SlyX FANCL_C PF11793.8 VBB29337.1 - 0.27 11.4 11.3 0.37 11.0 7.3 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain DUF4795 PF16043.5 VBB29337.1 - 0.96 9.0 13.9 0.12 11.9 7.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) zf-RING_4 PF14570.6 VBB29337.1 - 2.4 8.0 8.9 2.7 7.8 5.9 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 VBB29337.1 - 2.5 8.3 15.9 3.1 8.0 5.1 3.0 2 2 0 2 2 2 0 Zinc-ribbon like family zf-RING-like PF08746.11 VBB29337.1 - 4.6 7.6 16.0 0.083 13.2 8.8 1.9 2 0 0 2 2 1 0 RING-like domain Peptidase_S8 PF00082.22 VBB29339.1 - 2.7e-39 135.2 2.1 3.9e-39 134.7 2.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 VBB29339.1 - 1.1e-21 76.6 0.1 3.3e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 VBB29339.1 - 5.6e-17 62.3 1.1 1.1e-16 61.4 1.1 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 VBB29339.1 - 0.006 17.1 0.4 0.012 16.1 0.4 1.5 1 0 0 1 1 1 1 N-terminal of Subtilase family Epimerase_2 PF02350.19 VBB29339.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase CSD PF00313.22 VBB29340.1 - 6e-17 61.3 0.2 1.8e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 VBB29340.1 - 7.6 6.8 13.6 1.1 9.5 1.2 2.9 2 1 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 VBB29341.1 - 1.6e-20 73.0 2.5 5.5e-06 27.0 0.0 6.9 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29341.1 - 1.5e-17 63.7 0.0 0.015 15.6 0.0 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB29341.1 - 0.0019 17.6 0.0 0.63 9.3 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 VBB29341.1 - 0.0033 17.3 0.0 23 5.1 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 VBB29341.1 - 0.012 13.9 0.0 0.71 8.1 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz SR-25 PF10500.9 VBB29341.1 - 1.3 8.6 9.4 2 8.0 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRAM_LAG1_CLN8 PF03798.16 VBB29342.1 - 3.9e-25 88.8 22.3 3.9e-25 88.8 22.3 2.0 2 0 0 2 2 2 1 TLC domain COX5B PF01215.19 VBB29343.1 - 8.6e-07 28.7 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb ADK PF00406.22 VBB29344.1 - 7.7e-44 149.4 0.0 9.8e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 VBB29344.1 - 5.2e-32 111.1 0.0 8.5e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB29344.1 - 2.9e-12 47.3 0.0 4.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 VBB29344.1 - 3.4e-06 27.3 0.0 7.8e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 VBB29344.1 - 0.00033 20.6 1.1 0.11 12.4 0.3 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin PF02224.18 VBB29344.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 VBB29344.1 - 0.0031 16.8 0.0 0.0098 15.2 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 VBB29344.1 - 0.0063 16.4 0.0 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 VBB29344.1 - 0.0093 15.9 0.0 0.87 9.5 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 VBB29344.1 - 0.035 14.5 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 VBB29344.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 VBB29344.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 VBB29344.1 - 0.12 12.7 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 VBB29344.1 - 0.15 11.8 0.2 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 VBB29344.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PseudoU_synth_2 PF00849.22 VBB29345.1 - 2.1e-24 86.4 0.0 3.9e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase 7tm_1 PF00001.21 VBB29346.1 - 1.5e-11 44.1 28.1 1.6e-11 44.1 26.2 1.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 VBB29346.1 - 3.5e-08 33.1 24.9 6.2e-08 32.3 24.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw zf-RING_2 PF13639.6 VBB29347.1 - 7.6e-09 35.8 10.1 1.2e-08 35.2 10.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 VBB29347.1 - 4.1e-06 26.8 5.6 1.1e-05 25.4 5.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 VBB29347.1 - 5.7e-06 26.4 9.2 2.2e-05 24.5 9.2 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 VBB29347.1 - 3.4e-05 24.1 9.9 0.00011 22.4 9.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 VBB29347.1 - 3.5e-05 23.8 8.5 6.1e-05 23.1 8.5 1.4 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 VBB29347.1 - 4.4e-05 23.0 6.5 7.4e-05 22.3 6.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_9 PF13901.6 VBB29347.1 - 0.0014 18.7 2.7 0.0019 18.2 2.7 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 VBB29347.1 - 0.0018 18.5 10.6 0.0057 16.9 10.7 1.8 1 1 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 VBB29347.1 - 0.0022 17.8 9.3 0.0035 17.2 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB29347.1 - 0.0078 16.0 11.7 0.027 14.3 11.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 VBB29347.1 - 0.0095 15.8 7.3 0.017 15.0 7.3 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 VBB29347.1 - 0.032 14.1 6.5 0.032 14.1 6.5 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 VBB29347.1 - 0.038 14.1 5.3 0.068 13.3 5.3 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_11 PF17123.5 VBB29347.1 - 0.05 13.4 4.8 0.11 12.3 4.8 1.6 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 VBB29347.1 - 0.12 12.3 9.5 0.67 9.9 9.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 VBB29347.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-RING_4 PF14570.6 VBB29347.1 - 0.33 10.8 7.9 1.9 8.4 7.9 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 VBB29347.1 - 0.89 9.7 5.8 0.16 12.1 2.3 1.6 2 0 0 2 2 1 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 VBB29347.1 - 1.2 9.5 6.0 4.5 7.6 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon PHD_2 PF13831.6 VBB29347.1 - 1.5 8.5 9.1 4.8 6.8 4.3 2.3 1 1 1 2 2 2 0 PHD-finger zf-C2H2_4 PF13894.6 VBB29347.1 - 9.6 7.4 12.5 21 6.3 2.9 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Asp PF00026.23 VBB29348.1 - 1.4e-66 225.1 5.7 1.9e-66 224.7 5.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease PTPS PF01242.19 VBB29348.1 - 3e-20 72.4 0.0 5.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase TAXi_N PF14543.6 VBB29348.1 - 1.9e-09 38.0 0.1 1.3e-07 32.1 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal fn3_3 PF14686.6 VBB29348.1 - 0.0077 16.0 0.5 0.026 14.3 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II Pex24p PF06398.11 VBB29348.1 - 0.01 14.9 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin A1_Propeptide PF07966.12 VBB29348.1 - 0.028 14.3 0.7 0.06 13.2 0.7 1.5 1 0 0 1 1 1 0 A1 Propeptide zf-U1 PF06220.12 VBB29349.1 - 2.3e-23 81.6 4.0 3.1e-23 81.2 4.0 1.2 1 0 0 1 1 1 1 U1 zinc finger Arfaptin PF06456.13 VBB29350.1 - 1.8e-65 220.8 9.9 3e-65 220.0 9.9 1.4 1 0 0 1 1 1 1 Arfaptin-like domain DNA_pol_E_B PF04042.16 VBB29350.1 - 2.6e-41 141.3 0.8 3.9e-41 140.7 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 VBB29350.1 - 1.9e-14 53.7 1.0 5.8e-14 52.1 1.0 1.9 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal PDZ PF00595.24 VBB29350.1 - 3.4e-09 36.9 0.3 1.1e-08 35.2 0.3 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB29350.1 - 3.8e-08 33.1 0.0 9.4e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB29350.1 - 0.00014 22.2 0.0 0.00028 21.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Vps5 PF09325.10 VBB29350.1 - 0.042 13.4 3.2 0.26 10.8 0.1 2.9 2 1 0 2 2 2 0 Vps5 C terminal like Tricorn_PDZ PF14685.6 VBB29350.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain FLYWCH PF04500.16 VBB29351.1 - 5.7e-06 26.4 0.8 1.2e-05 25.3 0.8 1.5 1 0 0 1 1 1 1 FLYWCH zinc finger domain Ashwin PF15323.6 VBB29351.1 - 0.071 13.1 2.1 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Developmental protein zf-RING_5 PF14634.6 VBB29352.1 - 0.00017 21.4 8.1 0.00017 21.4 8.1 5.0 3 2 1 4 4 4 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB29352.1 - 0.00023 20.9 53.4 0.0018 18.1 7.4 4.5 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB29352.1 - 0.00036 20.3 18.1 0.00082 19.2 6.5 5.1 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB29352.1 - 0.00058 19.7 64.6 0.0057 16.5 10.5 5.3 3 1 2 5 5 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB29352.1 - 0.00076 19.8 8.7 0.00076 19.8 8.7 4.7 3 1 1 4 4 4 3 Ring finger domain zf-RING_UBOX PF13445.6 VBB29352.1 - 0.63 10.1 49.5 0.038 14.0 7.5 5.5 4 2 1 5 5 5 0 RING-type zinc-finger RNase_H PF00075.24 VBB29353.1 - 1.7e-13 50.9 0.0 4.4e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 RNase H Rab5ip PF07019.12 VBB29354.1 - 3.3e-14 53.2 9.0 4.8e-14 52.7 9.0 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Choline_transpo PF04515.12 VBB29354.1 - 0.0089 15.3 2.2 0.01 15.1 2.2 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter TGS PF02824.21 VBB29354.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 TGS domain Fringe PF02434.16 VBB29355.1 - 5.2e-53 180.1 0.0 6.7e-48 163.3 0.0 2.3 2 1 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 VBB29355.1 - 0.0001 22.2 0.2 0.11 12.3 0.0 3.4 1 1 2 3 3 3 2 Galactosyltransferase Glycos_transf_2 PF00535.26 VBB29355.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 BTB PF00651.31 VBB29357.1 - 2.1e-23 82.7 0.2 2.8e-22 79.1 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 VBB29357.1 - 5.2e-19 68.2 1.4 4.2e-18 65.4 0.8 2.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Pkinase PF00069.25 VBB29357.1 - 2.2e-13 50.2 0.5 4.4e-13 49.2 0.4 1.6 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 VBB29357.1 - 9.5e-13 48.4 0.0 5.2e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 F5/8 type C domain Pkinase_Tyr PF07714.17 VBB29357.1 - 4e-09 36.1 1.2 1.1e-08 34.7 0.5 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase MerR PF00376.23 VBB29358.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein Forkhead PF00250.18 VBB29359.1 - 1.6e-12 47.5 0.0 3.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Forkhead PF00250.18 VBB29360.1 - 7.4e-23 80.6 0.4 4.3e-22 78.2 0.3 2.3 2 0 0 2 2 2 1 Forkhead domain Pkinase PF00069.25 VBB29361.1 - 1.4e-75 254.1 0.0 1.9e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29361.1 - 3.4e-45 154.4 0.0 4.8e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 VBB29361.1 - 9e-14 51.9 0.0 4.8e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 VBB29361.1 - 3e-08 33.3 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 VBB29361.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 VBB29361.1 - 0.012 15.6 0.3 0.027 14.4 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 VBB29361.1 - 0.012 14.5 1.1 0.11 11.5 0.1 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 VBB29361.1 - 0.068 12.5 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HNF-1_N PF04814.13 VBB29362.1 - 3e-10 41.0 0.9 1.3e-09 39.0 0.0 2.3 2 1 1 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 VBB29362.1 - 2.5e-07 30.4 0.1 1.2e-06 28.3 0.1 2.2 1 1 0 1 1 1 1 Homeodomain HTH_37 PF13744.6 VBB29362.1 - 5e-05 23.2 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 VBB29362.1 - 0.00012 22.0 0.0 0.00076 19.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Homeobox_KN PF05920.11 VBB29362.1 - 0.0049 16.7 0.2 0.076 12.9 0.0 2.7 2 0 0 2 2 2 1 Homeobox KN domain HTH_31 PF13560.6 VBB29362.1 - 0.0083 16.5 0.0 0.025 14.9 0.0 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain DUF473 PF04322.12 VBB29362.1 - 0.033 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF473) HTH_19 PF12844.7 VBB29362.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Arnt_C PF18583.1 VBB29362.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain LIN52 PF10044.9 VBB29363.1 - 2.3e-26 92.3 0.0 2.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Retinal tissue protein DUF2164 PF09932.9 VBB29363.1 - 0.039 14.0 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) BTB PF00651.31 VBB29364.1 - 3e-06 27.4 0.8 8.7e-06 25.9 0.8 1.8 1 1 0 1 1 1 1 BTB/POZ domain SUIM_assoc PF16619.5 VBB29364.1 - 0.92 9.6 9.8 3.4 7.8 9.8 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TIL PF01826.17 VBB29365.1 - 4.1e-26 91.0 126.5 6.2e-08 32.8 15.5 10.5 10 1 1 11 11 11 6 Trypsin Inhibitor like cysteine rich domain WAP PF00095.21 VBB29365.1 - 2.2e-05 24.7 24.8 7.2e-05 23.1 9.7 12.0 9 5 0 10 10 10 4 WAP-type (Whey Acidic Protein) 'four-disulfide core' Collagen PF01391.18 VBB29366.1 - 1.8e-23 82.1 82.6 8.8e-10 38.2 23.3 4.1 3 1 1 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB29366.1 - 2.4e-13 49.9 0.1 3.5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain MARVEL PF01284.23 VBB29367.1 - 3.3e-12 46.6 9.3 4.1e-12 46.3 9.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4181 PF13789.6 VBB29367.1 - 0.061 13.6 0.8 0.11 12.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Fig1 PF12351.8 VBB29367.1 - 0.1 12.5 1.4 0.18 11.7 1.5 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3262 PF11660.8 VBB29367.1 - 0.27 11.6 4.5 0.26 11.7 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3262) Mob1_phocein PF03637.17 VBB29369.1 - 2.1e-44 151.5 0.5 3e-44 151.0 0.5 1.2 1 0 0 1 1 1 1 Mob1/phocein family EF-hand_1 PF00036.32 VBB29370.1 - 4.3e-17 60.3 16.8 0.0061 16.0 0.7 6.7 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 VBB29370.1 - 1.6e-15 57.3 22.9 1.6e-05 25.3 4.6 3.9 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 VBB29370.1 - 1.9e-14 52.3 17.2 0.00027 20.6 0.2 6.4 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 VBB29370.1 - 3.7e-09 35.7 25.2 0.052 13.1 0.2 6.0 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 VBB29370.1 - 2.3e-05 24.1 13.5 0.048 13.5 1.0 5.5 4 1 1 5 5 5 3 EF-hand domain pair CENP-B_dimeris PF09026.10 VBB29370.1 - 0.0016 18.8 0.8 0.0016 18.8 0.8 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain SPARC_Ca_bdg PF10591.9 VBB29370.1 - 0.058 13.7 9.0 1.3 9.3 0.1 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Cyanate_lyase PF02560.14 VBB29371.1 - 3.1e-32 110.2 0.0 5.4e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain 7tm_1 PF00001.21 VBB29372.1 - 1.4e-05 24.6 7.0 2.3e-05 23.9 7.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB29372.1 - 0.0021 17.5 18.3 0.0083 15.5 18.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SH3_9 PF14604.6 VBB29373.1 - 4.4e-13 48.9 0.2 8.3e-13 48.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB29373.1 - 7.3e-12 44.7 0.4 1.7e-11 43.5 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB29373.1 - 1.3e-08 34.4 0.0 2.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Cofilin_ADF PF00241.20 VBB29373.1 - 2e-07 30.8 0.5 1.1e-06 28.4 0.0 2.5 3 1 0 3 3 3 1 Cofilin/tropomyosin-type actin-binding protein HSP90 PF00183.18 VBB29374.1 - 3.7e-88 296.7 10.0 1.4e-86 291.4 4.5 2.1 1 1 1 2 2 2 2 Hsp90 protein DER1 PF04511.15 VBB29374.1 - 8.6e-55 185.6 24.6 5.7e-54 183.0 15.1 2.3 1 1 1 2 2 2 2 Der1-like family HATPase_c_3 PF13589.6 VBB29374.1 - 7.4e-14 51.7 0.1 1.5e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 VBB29374.1 - 2.6e-09 37.6 0.1 5e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myb_DNA-bind_7 PF15963.5 VBB29375.1 - 2.2e-05 24.3 0.3 6.7e-05 22.7 0.3 1.8 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 VBB29375.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain GlutR_dimer PF00745.20 VBB29375.1 - 0.088 13.3 0.0 27 5.3 0.0 2.8 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DEAD PF00270.29 VBB29376.1 - 6.9e-50 169.2 0.0 1.3e-48 165.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB29376.1 - 1.2e-25 90.0 0.0 7.2e-25 87.5 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB29376.1 - 1.1e-06 28.8 0.0 4.1e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 VBB29376.1 - 0.0063 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ABC_membrane PF00664.23 VBB29377.1 - 8.6e-05 22.3 4.5 8.6e-05 22.3 4.5 2.9 2 1 1 3 3 3 1 ABC transporter transmembrane region DUF2852 PF11014.8 VBB29377.1 - 0.26 11.5 2.5 0.4 10.8 0.4 2.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2852) CH PF00307.31 VBB29378.1 - 6.8e-05 23.0 2.1 0.0061 16.7 0.0 3.9 4 0 0 4 4 4 1 Calponin homology (CH) domain GTP-bdg_N PF13167.6 VBB29378.1 - 0.066 13.9 1.0 6.8 7.4 0.0 3.2 3 0 0 3 3 3 0 GTP-binding GTPase N-terminal CEL_III_C PF18054.1 VBB29378.1 - 0.39 10.8 5.5 1.5 8.8 2.7 2.3 2 0 0 2 2 2 0 CEL-III C-terminal SSP160 PF06933.11 VBB29378.1 - 2.8 6.1 9.4 3.8 5.6 9.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DAO PF01266.24 VBB29379.1 - 7.2e-49 167.2 0.1 2.3e-47 162.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 VBB29379.1 - 2.8e-41 140.3 0.1 5.4e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 VBB29379.1 - 2.5e-11 43.9 1.7 5.7e-11 42.7 1.7 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 VBB29379.1 - 8e-09 34.4 0.1 0.001 18.4 0.1 2.8 2 0 0 2 2 2 2 EF hand FAD_binding_2 PF00890.24 VBB29379.1 - 3e-08 33.2 2.5 0.00015 21.0 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain EF-hand_6 PF13405.6 VBB29379.1 - 6.6e-08 31.9 1.9 0.0045 16.8 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 VBB29379.1 - 1.4e-05 24.9 0.5 4.5e-05 23.2 0.4 2.0 1 1 1 2 2 2 1 EF-hand domain pair Pyr_redox_2 PF07992.14 VBB29379.1 - 0.00047 19.5 0.5 0.0078 15.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 VBB29379.1 - 0.00062 19.0 0.4 0.031 13.4 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 VBB29379.1 - 0.00099 18.6 0.5 0.00099 18.6 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF5580 PF17743.1 VBB29379.1 - 0.0026 16.4 0.2 0.0038 15.8 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 VBB29379.1 - 0.0031 16.9 0.6 0.11 12.1 0.1 3.0 3 0 0 3 3 3 1 EF hand HI0933_like PF03486.14 VBB29379.1 - 0.06 12.0 0.2 0.15 10.7 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 VBB29379.1 - 0.15 12.5 0.2 37 4.8 0.1 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 VBB29379.1 - 0.5 10.6 2.5 0.72 10.1 0.3 2.5 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain fn3 PF00041.21 VBB29380.1 - 1.9e-14 53.7 9.7 2.3e-06 27.8 0.1 5.1 5 1 0 5 5 5 3 Fibronectin type III domain I-set PF07679.16 VBB29380.1 - 0.00059 19.8 0.1 0.008 16.2 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB29380.1 - 0.0015 19.1 0.0 0.014 15.9 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 VBB29380.1 - 0.043 14.1 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 VBB29380.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Big_4 PF07532.11 VBB29380.1 - 0.058 13.1 0.9 15 5.4 0.0 3.4 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) Pro_isomerase PF00160.21 VBB29381.1 - 2e-36 125.7 0.4 2e-36 125.7 0.4 2.5 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc4 PF05132.14 VBB29381.1 - 0.24 11.8 3.9 0.27 11.6 3.9 1.3 1 1 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 VBB29381.1 - 0.96 7.7 4.3 1.1 7.4 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 VBB29381.1 - 1.3 8.5 6.8 1.5 8.3 6.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 VBB29381.1 - 1.8 8.2 4.7 2.6 7.7 4.7 1.2 1 0 0 1 1 1 0 Connexin Ion_trans_2 PF07885.16 VBB29382.1 - 4.8e-21 74.5 25.8 1.2e-10 41.2 2.5 3.1 2 1 1 3 3 3 2 Ion channel CoatB PF10389.9 VBB29382.1 - 0.064 13.1 0.6 0.064 13.1 0.6 2.5 3 0 0 3 3 3 0 Bacteriophage coat protein B Fcf2 PF08698.11 VBB29383.1 - 5.2e-31 106.9 5.2 5.7e-31 106.8 2.8 2.2 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing F-box-like PF12937.7 VBB29384.1 - 2.2e-08 33.9 0.7 4.3e-08 32.9 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB29384.1 - 2.1e-06 27.4 2.8 3.1e-06 26.9 0.8 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 VBB29384.1 - 4.1e-05 23.9 10.5 0.57 10.7 0.4 6.0 2 1 3 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB29384.1 - 0.00037 20.3 4.5 0.62 10.3 0.0 6.0 7 1 0 7 7 7 1 Leucine Rich repeat Preseq_ALAS PF09029.10 VBB29384.1 - 0.38 11.2 2.9 3.7 8.1 0.0 3.4 3 0 0 3 3 3 0 5-aminolevulinate synthase presequence zf-Di19 PF05605.12 VBB29387.1 - 7.5e-05 22.9 5.7 0.05 13.9 0.1 2.8 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 VBB29387.1 - 0.00046 20.9 3.7 1.6 9.5 0.1 3.6 3 1 0 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 VBB29387.1 - 0.0013 19.4 14.3 0.23 12.4 2.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB29387.1 - 0.005 17.2 2.6 0.005 17.2 2.6 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 VBB29387.1 - 0.027 15.1 1.6 5.7 7.6 0.0 2.9 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 VBB29387.1 - 0.32 10.8 5.7 0.12 12.1 2.2 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 VBB29387.1 - 2 9.0 12.5 5.4 7.6 0.0 4.3 5 0 0 5 5 5 0 Zinc-finger double domain GH97_C PF14509.6 VBB29389.1 - 0.023 14.9 0.3 0.069 13.4 0.3 1.9 1 1 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation ADK PF00406.22 VBB29390.1 - 6.1e-51 172.5 0.0 1.6e-50 171.1 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase Bud13 PF09736.9 VBB29390.1 - 1.6e-40 138.9 16.3 1.6e-40 138.9 16.3 3.4 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex AAA_17 PF13207.6 VBB29390.1 - 3.3e-35 121.5 0.1 3.3e-35 121.5 0.1 2.6 3 0 0 3 3 3 1 AAA domain TB2_DP1_HVA22 PF03134.19 VBB29390.1 - 2.7e-12 46.4 9.2 5.2e-12 45.5 9.2 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family AAA_33 PF13671.6 VBB29390.1 - 0.00012 22.3 0.0 0.0011 19.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 VBB29390.1 - 0.002 18.7 5.8 0.0056 17.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain Zip PF02535.22 VBB29391.1 - 8.5e-76 255.3 32.5 3e-75 253.5 10.3 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter DUF5134 PF17197.4 VBB29391.1 - 0.069 13.0 3.4 1 9.3 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF5134) V_ATPase_I PF01496.19 VBB29391.1 - 0.2 9.6 7.5 0.02 12.8 2.4 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUN14 PF04930.15 VBB29391.1 - 0.22 12.0 4.0 1.8 9.0 0.0 3.1 3 1 0 3 3 3 0 FUN14 family DUF3267 PF11667.8 VBB29391.1 - 0.34 11.2 0.1 0.34 11.2 0.1 2.6 3 0 0 3 3 3 0 Putative zincin peptidase DUF4834 PF16118.5 VBB29391.1 - 0.58 11.1 5.7 2.4 9.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4079 PF13301.6 VBB29391.1 - 0.81 9.8 8.2 16 5.6 0.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Neur_chan_memb PF02932.16 VBB29391.1 - 1.1 9.3 5.3 5 7.1 1.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2157 PF09925.9 VBB29391.1 - 1.7 8.4 9.4 9.1 6.1 1.8 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) AAA PF00004.29 VBB29392.1 - 1.6e-12 48.0 0.0 3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 VBB29392.1 - 2.7e-06 27.4 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 VBB29392.1 - 2.9e-06 27.8 0.1 0.00041 20.8 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain Rep_fac_C PF08542.11 VBB29392.1 - 9.5e-06 25.9 0.1 6.5e-05 23.3 0.0 2.5 2 1 0 2 2 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 VBB29392.1 - 2.8e-05 24.4 0.0 0.00035 20.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 VBB29392.1 - 6.4e-05 22.8 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 VBB29392.1 - 8.2e-05 22.4 0.0 0.0021 17.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 VBB29392.1 - 0.00017 21.9 0.0 0.00054 20.3 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain RuvB_N PF05496.12 VBB29392.1 - 0.00023 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 VBB29392.1 - 0.00082 19.2 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 VBB29392.1 - 0.001 19.4 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 VBB29392.1 - 0.0016 17.7 0.0 0.023 13.9 0.0 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 VBB29392.1 - 0.0024 17.6 0.0 0.006 16.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 VBB29392.1 - 0.0034 16.8 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB29392.1 - 0.0036 17.3 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 VBB29392.1 - 0.0077 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 VBB29392.1 - 0.0079 16.8 0.0 0.02 15.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain DEAD PF00270.29 VBB29392.1 - 0.012 15.3 0.0 1.5 8.5 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 VBB29392.1 - 0.013 15.0 0.0 0.72 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 VBB29392.1 - 0.017 15.4 0.0 0.072 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 VBB29392.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 VBB29392.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 VBB29392.1 - 0.021 14.3 0.1 2.5 7.5 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein DUF2075 PF09848.9 VBB29392.1 - 0.048 12.9 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Vel1p PF10339.9 VBB29392.1 - 0.051 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive AAA_25 PF13481.6 VBB29392.1 - 0.055 13.0 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 VBB29392.1 - 0.055 13.1 0.0 0.089 12.4 0.0 1.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 VBB29392.1 - 0.075 12.8 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 VBB29392.1 - 0.08 12.9 0.0 0.26 11.2 0.0 1.9 2 1 0 2 2 1 0 NACHT domain DUF615 PF04751.14 VBB29392.1 - 0.083 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) AAA_7 PF12775.7 VBB29392.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 VBB29392.1 - 0.11 12.2 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 VBB29392.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Homeodomain PF00046.29 VBB29393.1 - 1.8e-18 66.1 0.3 3.1e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 VBB29393.1 - 4.5e-15 55.6 8.3 8e-15 54.8 8.3 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 VBB29393.1 - 0.0023 17.8 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Sgf11 PF08209.11 VBB29393.1 - 0.031 13.8 2.6 2 8.0 0.3 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) HrpB7 PF09486.10 VBB29393.1 - 0.071 13.5 0.2 0.14 12.5 0.1 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SLR1-BP PF07333.12 VBB29393.1 - 0.12 12.8 4.7 0.31 11.5 4.7 1.6 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) HypA PF01155.19 VBB29393.1 - 0.67 10.0 4.4 0.44 10.6 2.0 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-SNAP50_C PF12251.8 VBB29393.1 - 1 9.0 8.2 0.17 11.6 3.7 1.8 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal C1_1 PF00130.22 VBB29393.1 - 7 6.6 11.4 2e+02 1.9 11.4 2.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Abhydrolase_1 PF00561.20 VBB29394.1 - 0.039 13.6 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1168 PF06658.12 VBB29395.1 - 8.6e-37 126.0 18.4 8.6e-37 126.0 18.4 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1168) UPF0560 PF10577.9 VBB29395.1 - 8.2 4.8 14.6 12 4.3 14.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Chromo_shadow PF01393.19 VBB29396.1 - 6e-28 96.7 0.1 1.2e-25 89.3 0.0 2.5 2 1 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 VBB29396.1 - 2e-20 72.5 0.0 1.8e-16 59.8 0.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 VBB29396.1 - 0.094 12.9 0.4 20 5.4 0.1 2.9 2 1 0 2 2 2 0 Polycomb-like MTF2 factor 2 NARP1 PF12569.8 VBB29397.1 - 6.2e-205 682.0 13.2 6.2e-205 682.0 13.2 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 VBB29397.1 - 1.3e-14 53.1 27.6 0.0025 17.9 0.0 9.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 VBB29397.1 - 1.5e-11 43.6 34.5 3.7e-05 23.3 0.2 8.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29397.1 - 4.9e-11 41.9 31.9 0.0016 18.4 0.0 10.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29397.1 - 5.9e-10 39.1 13.6 0.098 13.5 0.0 9.3 6 2 5 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB29397.1 - 9.6e-08 31.6 0.4 6.2e-06 25.8 0.0 6.5 8 1 1 9 9 9 2 TPR repeat TPR_19 PF14559.6 VBB29397.1 - 2.5e-07 31.1 22.0 0.044 14.3 0.9 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 VBB29397.1 - 4.6e-07 29.3 12.9 7.9e-05 22.0 0.8 4.2 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29397.1 - 7.3e-05 23.0 18.3 0.0041 17.4 0.2 6.5 5 3 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29397.1 - 8.4e-05 22.7 20.9 0.0021 18.3 0.4 6.3 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 VBB29397.1 - 0.00081 19.6 15.7 17 6.1 0.2 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 VBB29397.1 - 0.0015 18.5 2.0 0.29 11.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB29397.1 - 0.0085 16.2 7.0 0.34 11.1 0.3 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB29397.1 - 0.015 15.3 5.5 2.8 8.2 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat EMP24_GP25L PF01105.24 VBB29397.1 - 0.076 12.9 0.3 0.076 12.9 0.3 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TPR_16 PF13432.6 VBB29397.1 - 0.13 13.0 14.0 2.3 8.9 0.0 6.4 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 VBB29397.1 - 0.28 11.1 2.1 14 5.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB29397.1 - 0.68 10.0 21.0 2.7 8.1 0.2 6.5 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 VBB29398.1 - 9.8e-61 205.4 0.1 1.9e-60 204.4 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29398.1 - 2.8e-23 82.5 0.0 6.2e-23 81.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB29398.1 - 6.4e-06 25.2 0.0 1.5e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 VBB29398.1 - 0.0006 19.2 0.0 0.0048 16.2 0.0 2.2 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 VBB29398.1 - 0.0016 17.9 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB29398.1 - 0.017 15.1 0.4 0.21 11.5 0.2 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 VBB29398.1 - 0.025 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 VBB29398.1 - 0.049 13.2 0.3 0.3 10.7 0.0 2.3 3 0 0 3 3 3 0 RIO1 family zf-C2H2 PF00096.26 VBB29399.1 - 1.2e-20 72.7 21.2 4.2e-05 23.8 0.7 6.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB29399.1 - 9.3e-14 51.1 14.9 5.9e-07 29.6 0.9 5.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB29399.1 - 1.1e-07 32.0 21.4 0.012 16.3 0.4 6.2 5 0 0 5 5 5 2 C2H2-type zinc finger FOXP-CC PF16159.5 VBB29399.1 - 3e-07 31.0 11.8 0.25 12.0 0.1 5.7 1 1 4 5 5 5 3 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 VBB29399.1 - 0.00045 19.9 0.5 0.56 10.0 0.1 3.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 VBB29399.1 - 0.0087 16.2 8.5 0.77 9.9 1.4 3.5 2 1 0 3 3 3 1 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 VBB29399.1 - 0.0097 16.2 6.9 26 5.2 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB29399.1 - 0.54 10.7 5.1 40 4.8 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_Hakai PF18408.1 VBB29399.1 - 0.85 9.4 8.2 3.3 7.5 0.1 4.2 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain zf-TRAF PF02176.18 VBB29399.1 - 3.3 8.5 7.5 7.6 7.3 1.4 3.1 2 0 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.12 VBB29399.1 - 6.1 7.2 9.3 6.3 7.2 0.1 3.7 2 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 VBB29399.1 - 7.6 6.4 10.0 5.4 6.9 0.2 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain NHL PF01436.21 VBB29400.1 - 2.3e-42 140.9 17.0 7.4e-09 35.2 0.2 7.2 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 VBB29400.1 - 7.3e-16 58.2 5.4 1.4e-09 37.6 0.2 4.3 2 1 2 4 4 4 3 6-bladed beta-propeller zf-C3HC4 PF00097.25 VBB29400.1 - 4.8e-09 35.9 12.9 4.8e-09 35.9 12.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB29400.1 - 1.4e-07 31.4 12.5 1.4e-07 31.4 12.5 2.4 2 0 0 2 2 1 1 RING-type zinc-finger SGL PF08450.12 VBB29400.1 - 3.5e-06 26.8 0.3 0.0015 18.1 0.0 2.5 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region TolB_like PF15869.5 VBB29400.1 - 3.7e-06 26.4 0.1 0.00023 20.5 0.1 3.2 1 1 2 3 3 3 2 TolB-like 6-blade propeller-like zf-C3HC4_3 PF13920.6 VBB29400.1 - 2.2e-05 24.2 11.9 2.2e-05 24.2 11.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB29400.1 - 2.9e-05 23.9 11.0 2.9e-05 23.9 11.0 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB29400.1 - 8.7e-05 22.3 14.2 8.7e-05 22.3 14.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB29400.1 - 0.00015 21.8 13.4 0.00015 21.8 13.4 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 VBB29400.1 - 0.0004 20.7 13.4 0.0004 20.7 13.4 2.7 2 0 0 2 2 2 1 Ring finger domain DUF4934 PF16288.5 VBB29400.1 - 0.028 14.4 1.4 3 7.8 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4934) SBBP PF06739.11 VBB29400.1 - 0.1 12.6 2.5 0.5 10.4 0.1 3.1 3 0 0 3 3 3 0 Beta-propeller repeat zf-RING_11 PF17123.5 VBB29400.1 - 0.36 10.6 5.7 1.2 8.9 5.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger Myb_DNA-binding PF00249.31 VBB29401.1 - 6.4e-09 35.9 1.6 1.9e-07 31.1 0.9 2.8 2 1 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 VBB29401.1 - 0.1 12.6 0.0 0.1 12.6 0.0 3.1 3 1 0 3 3 3 0 SLIDE Spectrin PF00435.21 VBB29402.1 - 8.8e-63 209.4 96.4 9.1e-11 42.2 0.9 12.4 11 1 1 12 12 12 11 Spectrin repeat GAS2 PF02187.17 VBB29402.1 - 1.9e-30 104.7 1.1 6e-30 103.1 1.1 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_7 PF13499.6 VBB29402.1 - 0.0057 17.1 0.1 0.06 13.8 0.1 3.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB29402.1 - 0.0091 15.9 0.2 8.6 6.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain V-SNARE PF05008.15 VBB29402.1 - 0.051 14.0 0.1 0.051 14.0 0.1 5.1 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus EF-hand_1 PF00036.32 VBB29402.1 - 0.12 11.9 1.4 16 5.4 0.9 2.9 2 0 0 2 2 2 0 EF hand DUF948 PF06103.11 VBB29402.1 - 1.1 9.6 17.9 0.52 10.6 2.6 6.4 7 1 0 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF2524 PF10732.9 VBB29402.1 - 2.6 8.4 14.2 2 8.8 0.4 5.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2524) DUF2680 PF10925.8 VBB29402.1 - 5.4 7.1 7.0 13 5.9 1.3 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) TPR_14 PF13428.6 VBB29402.1 - 7.6 7.7 9.2 0.8 10.7 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DRMBL PF07522.14 VBB29403.1 - 2.2e-05 24.6 0.0 4.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase CECR6_TMEM121 PF14997.6 VBB29405.1 - 0.12 12.2 0.3 0.16 11.8 0.3 1.1 1 0 0 1 1 1 0 CECR6/TMEM121 family LRR_8 PF13855.6 VBB29406.1 - 1.1e-17 63.6 26.3 3.3e-06 26.8 4.5 4.2 2 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 VBB29406.1 - 2.7e-15 56.2 26.4 1.8e-05 25.0 1.1 4.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) B3_4 PF03483.17 VBB29406.1 - 3.6e-08 33.3 0.0 7.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain LRR_9 PF14580.6 VBB29406.1 - 1.4e-05 24.7 10.3 0.0028 17.2 3.1 3.5 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 VBB29406.1 - 0.029 14.9 18.4 0.95 10.3 0.0 6.8 6 1 1 7 7 7 0 Leucine Rich Repeat T6PP_N PF18572.1 VBB29406.1 - 0.038 13.8 1.9 0.34 10.8 0.2 2.6 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain LRR_5 PF13306.6 VBB29406.1 - 0.053 13.5 3.8 1.3 9.0 1.6 2.6 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) SpoVG PF04026.12 VBB29406.1 - 0.078 13.2 0.0 0.91 9.8 0.0 2.3 2 0 0 2 2 2 0 SpoVG Rcd1 PF04078.13 VBB29407.1 - 1.6e-117 391.4 2.0 2.9e-117 390.6 2.0 1.4 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF4062 PF13271.6 VBB29407.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) PCI PF01399.27 VBB29408.1 - 1.9e-10 41.2 2.2 4.6e-10 40.0 0.9 2.3 2 1 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 VBB29408.1 - 0.00056 19.5 0.9 0.0013 18.3 0.9 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix FliG_N PF14842.6 VBB29408.1 - 0.036 14.6 0.1 0.1 13.2 0.1 1.8 1 0 0 1 1 1 0 FliG N-terminal domain DUF2526 PF10735.9 VBB29408.1 - 0.049 13.8 0.1 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Sel1 PF08238.12 VBB29409.1 - 4.2e-52 173.4 45.1 1e-07 32.4 0.0 11.9 12 0 0 12 12 12 10 Sel1 repeat Ribosomal_S5_C PF03719.15 VBB29409.1 - 5e-17 61.1 0.0 1.2e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 VBB29409.1 - 5.2e-17 61.6 0.4 1.1e-16 60.5 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain TipAS PF07739.13 VBB29409.1 - 0.0079 16.7 11.9 0.12 12.9 2.5 4.7 3 1 1 4 4 4 2 TipAS antibiotic-recognition domain TAP_C PF03943.13 VBB29409.1 - 0.049 13.3 1.3 9.7 5.9 0.0 3.4 4 0 0 4 4 4 0 TAP C-terminal domain NLRC4_HD2 PF17776.1 VBB29409.1 - 0.063 13.8 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 NLRC4 helical domain HD2 GDYXXLXY PF14345.6 VBB29410.1 - 0.15 11.9 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 GDYXXLXY protein SMC_N PF02463.19 VBB29411.1 - 6.8e-71 238.2 12.8 2.4e-70 236.4 12.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 VBB29411.1 - 3e-22 79.1 0.3 1.6e-21 76.8 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 VBB29411.1 - 5.1e-17 62.6 0.1 5.1e-17 62.6 0.1 5.3 3 2 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 VBB29411.1 - 1.9e-11 44.4 11.6 8.2e-06 25.8 0.1 3.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 VBB29411.1 - 3.4e-05 23.5 0.0 8.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 VBB29411.1 - 0.00047 19.1 11.6 0.00047 19.1 11.6 7.0 4 2 3 7 7 7 1 Spc7 kinetochore protein ABC_tran PF00005.27 VBB29411.1 - 0.083 13.4 0.0 0.083 13.4 0.0 6.3 5 2 0 5 5 5 0 ABC transporter Nas2_N PF18265.1 VBB29411.1 - 1.3 9.0 14.5 0.094 12.6 2.2 5.4 3 1 1 4 4 4 0 Nas2 N_terminal domain Ribosomal_L7Ae PF01248.26 VBB29412.1 - 0.084 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.32 VBB29413.1 - 1.8e-32 110.9 14.4 3.5e-07 30.8 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29413.1 - 6.4e-09 36.0 0.3 0.024 14.9 0.1 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GRASP55_65 PF04495.14 VBB29414.1 - 1.4e-72 242.4 0.1 1.9e-51 174.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 VBB29414.1 - 6.1e-08 32.9 0.0 0.0026 18.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB29414.1 - 1.8e-07 30.9 0.0 0.0081 16.0 0.0 2.7 2 0 0 2 2 2 2 PDZ domain WD40 PF00400.32 VBB29415.1 - 1.2e-30 105.1 10.9 1.5e-07 32.0 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29415.1 - 4.5e-14 52.5 4.0 0.0017 18.6 0.0 5.2 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 VBB29415.1 - 6.9e-11 41.6 0.1 1.4e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 VBB29415.1 - 8.3e-10 37.9 0.5 0.0018 17.0 0.2 3.9 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 VBB29415.1 - 6.1e-07 28.7 4.7 0.092 11.7 0.0 4.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 VBB29415.1 - 1.2e-05 25.3 1.1 0.9 9.4 0.0 3.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 VBB29415.1 - 0.0014 17.3 0.1 0.019 13.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.11 VBB29415.1 - 0.0083 15.2 0.2 1.9 7.5 0.0 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF1513) PALB2_WD40 PF16756.5 VBB29415.1 - 0.079 11.9 3.1 2.8 6.7 1.7 3.1 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain FOP_dimer PF09398.10 VBB29415.1 - 0.14 12.4 0.1 0.44 10.8 0.1 1.8 1 0 0 1 1 1 0 FOP N terminal dimerisation domain CXCXC PF03128.14 VBB29415.1 - 0.17 12.4 0.7 0.45 11.1 0.7 1.8 1 0 0 1 1 1 0 CXCXC repeat PQQ_3 PF13570.6 VBB29415.1 - 0.24 12.0 0.7 3.5 8.2 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Pkinase PF00069.25 VBB29416.1 - 5.7e-48 163.6 0.6 8.4e-48 163.0 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29416.1 - 1.7e-28 99.6 0.2 2.8e-28 98.9 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 VBB29416.1 - 3.9e-10 39.7 0.7 3.1e-09 36.8 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB29416.1 - 3e-07 30.9 0.1 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain fn3 PF00041.21 VBB29416.1 - 0.00014 22.2 0.1 0.002 18.4 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain SH3_2 PF07653.17 VBB29416.1 - 0.0005 19.7 0.1 0.0015 18.1 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB29416.1 - 0.0069 16.0 0.1 0.042 13.5 0.0 2.4 3 0 0 3 3 3 1 SH3 domain ig PF00047.25 VBB29416.1 - 0.018 15.2 0.4 0.062 13.5 0.1 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Kinase-like PF14531.6 VBB29416.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RasGEF PF00617.19 VBB29417.1 - 1.6e-50 171.8 0.9 3.2e-50 170.8 0.9 1.5 1 0 0 1 1 1 1 RasGEF domain Ish1 PF10281.9 VBB29417.1 - 0.039 14.3 0.5 0.3 11.4 0.0 2.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein PH_8 PF15409.6 VBB29417.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain NFACT-R_1 PF05670.13 VBB29418.1 - 1.4e-41 141.5 0.0 2.4e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain FTO_NTD PF12933.7 VBB29418.1 - 0.035 13.4 0.6 0.053 12.8 0.6 1.3 1 0 0 1 1 1 0 FTO catalytic domain Not1 PF04054.15 VBB29418.1 - 0.12 11.3 0.2 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF1764 PF08576.10 VBB29418.1 - 2.8 8.9 12.5 4.7 8.2 12.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pkinase_Tyr PF07714.17 VBB29419.1 - 2.9e-56 190.6 0.0 1.6e-53 181.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 VBB29419.1 - 1.2e-30 106.8 0.1 1.3e-28 100.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.14 VBB29419.1 - 0.0033 16.8 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH2 PF00017.24 VBB29419.1 - 0.15 12.2 0.2 0.58 10.3 0.2 2.1 1 0 0 1 1 1 0 SH2 domain RasGEF PF00617.19 VBB29420.1 - 1.7e-52 178.2 0.0 3.1e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 VBB29420.1 - 4.6e-17 62.2 0.1 1.2e-16 60.9 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 VBB29420.1 - 3e-11 43.8 0.0 8.6e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ribosomal_S17_N PF16205.5 VBB29421.1 - 2.2e-29 101.6 3.2 4.9e-14 52.4 0.1 2.5 3 0 0 3 3 3 2 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 VBB29421.1 - 6.3e-26 90.3 2.7 9.3e-26 89.7 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.11 VBB29421.1 - 0.024 14.1 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Myosin_head PF00063.21 VBB29422.1 - 6.1e-293 973.2 3.6 6.1e-293 973.2 3.6 3.1 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 VBB29422.1 - 3e-149 498.9 264.4 3.7e-149 498.6 264.4 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 VBB29422.1 - 9.3e-15 54.2 2.2 2.2e-14 53.0 2.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain SHE3 PF17078.5 VBB29422.1 - 0.0016 18.2 12.9 0.0016 18.2 12.9 9.4 2 2 5 9 9 9 2 SWI5-dependent HO expression protein 3 RRM_1 PF00076.22 VBB29423.1 - 2.7e-85 280.2 1.8 4.1e-17 61.8 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB29423.1 - 4.4e-08 33.1 0.5 0.2 11.7 0.0 6.4 6 1 0 7 7 7 2 RNA binding motif RRM_occluded PF16842.5 VBB29423.1 - 1.4e-07 31.3 0.0 0.012 15.4 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 VBB29423.1 - 1.6e-07 31.2 0.2 0.0038 17.2 0.0 4.7 6 0 0 6 6 6 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 VBB29423.1 - 5.5e-05 23.2 0.0 0.95 9.6 0.0 4.7 5 0 0 5 5 5 2 RNA recognition motif Sulfatase PF00884.23 VBB29424.1 - 1e-69 235.3 0.0 1.4e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 VBB29424.1 - 6.5e-29 101.2 0.2 1.3e-28 100.2 0.2 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 VBB29424.1 - 3.2e-05 23.7 0.1 0.00014 21.6 0.1 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 VBB29424.1 - 0.004 15.8 0.1 0.0057 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) SPT16 PF08644.11 VBB29425.1 - 5e-55 185.8 0.1 5e-55 185.8 0.1 2.6 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 VBB29425.1 - 3.4e-44 150.5 0.9 8e-44 149.3 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 VBB29425.1 - 7.8e-25 87.8 0.0 1.3e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 VBB29425.1 - 5.3e-17 62.0 0.6 2e-16 60.1 0.2 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Acetyltransf_1 PF00583.25 VBB29426.1 - 1.2e-16 61.0 0.0 2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 VBB29426.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 VBB29426.1 - 3e-10 40.1 0.1 6.5e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 VBB29426.1 - 3e-09 36.7 0.7 1.1e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 VBB29426.1 - 0.00058 19.6 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 VBB29426.1 - 0.0017 19.0 0.0 0.0042 17.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 VBB29426.1 - 0.014 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pan3_PK PF18101.1 VBB29426.1 - 0.028 14.4 0.8 0.065 13.2 0.1 1.9 2 0 0 2 2 2 0 Pan3 Pseudokinase domain Acetyltransf_4 PF13420.7 VBB29426.1 - 0.041 14.0 0.0 0.077 13.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 VBB29426.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HTH_41 PF14502.6 VBB29426.1 - 0.097 12.4 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PanZ PF12568.8 VBB29426.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ PrmA PF06325.13 VBB29427.1 - 6.4e-10 38.9 1.2 8.6e-10 38.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 VBB29427.1 - 7e-08 33.1 0.0 2.8e-07 31.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB29427.1 - 3.5e-06 27.6 0.0 9.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB29427.1 - 7.6e-06 25.8 0.1 1.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB29427.1 - 7.3e-05 22.4 0.7 0.00015 21.4 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 VBB29427.1 - 0.00049 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB29427.1 - 0.00069 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB29427.1 - 0.0027 18.4 0.0 0.0072 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 VBB29427.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 VBB29427.1 - 0.0074 15.6 1.5 0.0079 15.5 0.1 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 VBB29427.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 VBB29427.1 - 0.011 15.4 1.1 0.04 13.7 0.1 2.2 2 0 0 2 2 2 0 Lysine methyltransferase DOT1 PF08123.13 VBB29427.1 - 0.012 15.2 0.1 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_9 PF08003.11 VBB29427.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 VBB29427.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Porphobil_deam PF01379.20 VBB29427.1 - 0.057 12.9 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain Mito_carr PF00153.27 VBB29428.1 - 1.1e-62 207.9 2.3 6.2e-21 74.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Topoisom_bac PF01131.20 VBB29429.1 - 7.1e-115 384.3 0.0 9e-115 384.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 VBB29429.1 - 8e-19 67.8 0.0 1.8e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.12 VBB29429.1 - 1.7e-15 56.8 3.7 4.7e-15 55.4 3.7 1.8 1 0 0 1 1 1 1 GRF zinc finger HET PF06985.11 VBB29429.1 - 0.2 12.0 0.7 0.46 10.8 0.7 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Bul1_C PF04426.12 VBB29429.1 - 0.2 11.0 2.2 0.41 10.0 2.2 1.4 1 0 0 1 1 1 0 Bul1 C terminus FliJ PF02050.16 VBB29429.1 - 0.27 11.4 3.7 0.61 10.3 3.7 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Med7 PF05983.11 VBB29430.1 - 4.2e-38 131.4 10.1 6.4e-38 130.8 7.6 2.4 2 1 0 2 2 2 1 MED7 protein zf-H2C2_2 PF13465.6 VBB29430.1 - 4.8e-08 33.1 26.9 1.6e-05 25.1 3.2 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB29430.1 - 4.9e-08 33.0 27.4 1.4e-05 25.2 1.2 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB29430.1 - 0.00015 22.3 24.5 0.00031 21.3 1.0 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB29430.1 - 0.019 15.3 0.1 0.019 15.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 VBB29430.1 - 0.025 15.0 0.1 0.025 15.0 0.1 3.1 3 0 0 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 VBB29430.1 - 0.03 14.3 0.9 0.03 14.3 0.9 3.9 4 0 0 4 4 3 0 C2H2-type zinc finger DUF3268 PF11672.8 VBB29430.1 - 0.049 13.9 2.0 0.16 12.3 2.0 1.9 1 0 0 1 1 1 0 zinc-finger-containing domain zf-H2C2_5 PF13909.6 VBB29430.1 - 1.2 9.0 16.2 0.052 13.3 4.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 VBB29430.1 - 1.8 8.9 8.5 3.5 8.0 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 VBB29430.1 - 4.3 7.5 15.6 38 4.5 5.4 3.7 3 0 0 3 3 3 0 Zinc ribbon domain HAT_KAT11 PF08214.11 VBB29432.1 - 5.9e-56 190.2 2.7 1.8e-55 188.6 2.7 1.9 1 1 0 1 1 1 1 Histone acetylation protein KIX PF02172.16 VBB29432.1 - 4.4e-34 116.6 0.8 1e-33 115.4 0.8 1.7 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.16 VBB29432.1 - 4.7e-25 87.8 50.9 3.7e-18 65.7 12.7 4.2 4 0 0 4 4 4 2 TAZ zinc finger DUF902 PF06001.13 VBB29432.1 - 1.6e-18 66.8 5.4 1.6e-18 66.8 5.4 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.25 VBB29432.1 - 1.7e-18 66.5 0.2 1.7e-18 66.5 0.2 2.6 3 0 0 3 3 3 1 Bromodomain ZZ PF00569.17 VBB29432.1 - 1.2e-08 34.6 7.9 1.2e-08 34.6 7.9 3.7 4 0 0 4 4 4 1 Zinc finger, ZZ type KIX_2 PF16987.5 VBB29432.1 - 1.6e-05 24.8 0.2 7.8e-05 22.6 0.2 2.3 1 0 0 1 1 1 1 KIX domain CAP PF00188.26 VBB29433.1 - 2.1e-21 77.1 7.3 3.4e-21 76.4 7.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LysM PF01476.20 VBB29434.1 - 2e-06 27.7 0.0 5.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 LysM domain Endonuc-BglII PF09195.11 VBB29434.1 - 0.12 12.2 1.0 0.36 10.7 0.4 2.2 2 1 0 2 2 2 0 Restriction endonuclease BglII TLD PF07534.16 VBB29435.1 - 6.7e-29 100.9 0.4 1.3e-28 99.9 0.4 1.5 1 0 0 1 1 1 1 TLD Intimin_C PF07979.11 VBB29437.1 - 0.084 13.3 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Intimin C-type lectin domain Ribosomal_L22e PF01776.17 VBB29438.1 - 2.1e-45 153.6 1.1 2.7e-45 153.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Inositol_P PF00459.25 VBB29439.1 - 3.8e-33 115.2 0.0 6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L27A PF00828.19 VBB29441.1 - 7.4e-10 39.6 0.0 1.1e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Rho_N PF07498.12 VBB29441.1 - 0.015 15.2 0.1 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain SprT-like PF10263.9 VBB29442.1 - 2.5e-24 85.3 0.3 6.2e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 VBB29442.1 - 6.7e-06 25.9 2.4 6.7e-06 25.9 2.4 2.3 2 0 0 2 2 2 1 SprT-like zinc ribbon domain HMG_box PF00505.19 VBB29442.1 - 0.017 15.5 1.7 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box Mg296 PF09644.10 VBB29442.1 - 0.018 15.2 2.1 0.053 13.6 2.1 1.8 1 0 0 1 1 1 0 Mg296 protein zf-RRN7 PF11781.8 VBB29442.1 - 0.08 12.6 1.2 2.9 7.6 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HD_3 PF13023.6 VBB29445.1 - 1.1e-43 149.0 0.2 1.6e-43 148.4 0.2 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 VBB29445.1 - 3.2e-13 49.9 0.1 5.4e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 VBB29445.1 - 5.8e-05 23.3 0.2 0.00018 21.7 0.2 1.8 1 1 0 1 1 1 1 HD domain HhH-GPD PF00730.25 VBB29446.1 - 4.7e-21 75.3 0.0 6.9e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 VBB29446.1 - 7.3e-08 31.9 0.0 1.6e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 VBB29446.1 - 0.0098 16.5 0.0 9.3 6.9 0.0 2.5 1 1 2 3 3 3 3 Helix-hairpin-helix domain RNA_pol_Rpb1_5 PF04998.17 VBB29447.1 - 3.6e-86 288.9 2.1 3.6e-86 288.9 1.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 VBB29447.1 - 4.5e-70 235.2 0.1 1e-69 234.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 VBB29447.1 - 1.9e-52 178.6 3.4 3.6e-49 167.8 0.3 3.1 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 VBB29447.1 - 1.2e-32 113.0 0.0 1.2e-30 106.6 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 VBB29447.1 - 6.5e-30 103.2 0.1 2.6e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 WD40 PF00400.32 VBB29448.1 - 3.2e-54 179.7 26.4 3.5e-09 37.1 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29448.1 - 1.5e-23 82.9 2.1 0.00033 20.9 0.0 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 VBB29448.1 - 6.1e-14 51.6 9.1 0.035 12.8 0.0 5.9 1 1 5 6 6 6 5 Nucleoporin Nup120/160 eIF2A PF08662.11 VBB29448.1 - 7.7e-11 42.2 0.3 2.4e-07 30.8 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 VBB29448.1 - 7.4e-09 35.0 9.5 0.13 11.2 0.6 4.4 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 VBB29448.1 - 1.3e-06 28.0 0.2 0.0048 16.3 0.0 3.3 1 1 2 4 4 4 2 WD40-like domain PALB2_WD40 PF16756.5 VBB29448.1 - 0.00016 20.7 4.3 0.33 9.8 1.9 4.4 1 1 2 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 VBB29448.1 - 0.00045 18.7 0.1 0.0075 14.6 0.0 2.0 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 VBB29448.1 - 0.0011 17.6 0.0 0.014 13.9 0.0 2.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain Big_7 PF17957.1 VBB29448.1 - 0.0069 17.1 1.9 0.74 10.6 0.4 2.9 2 1 0 2 2 2 1 Bacterial Ig domain VID27 PF08553.10 VBB29448.1 - 0.013 14.5 0.0 0.048 12.7 0.0 1.9 1 1 0 2 2 2 0 VID27 C-terminal WD40-like domain Spt20 PF12090.8 VBB29448.1 - 0.11 12.1 10.7 0.16 11.5 10.7 1.2 1 0 0 1 1 1 0 Spt20 family Kelch_6 PF13964.6 VBB29448.1 - 0.14 12.5 6.2 2.9 8.3 0.1 4.3 3 2 1 4 4 4 0 Kelch motif ANAPC_CDC26 PF10471.9 VBB29448.1 - 3.9 8.4 11.7 6.9 7.6 11.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Hira PF07569.11 VBB29448.1 - 6.4 6.4 0.0 6.4 6.4 0.0 4.8 6 1 1 7 7 7 0 TUP1-like enhancer of split Bax1-I PF01027.20 VBB29449.1 - 2.3e-32 112.5 22.0 3.2e-32 112.0 22.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PetG PF02529.15 VBB29449.1 - 0.1 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 CcmD PF04995.14 VBB29449.1 - 0.83 9.8 0.0 0.83 9.8 0.0 3.0 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DB PF01682.19 VBB29450.1 - 1.6e-09 37.9 8.2 1.6e-09 37.9 8.2 2.2 2 0 0 2 2 2 1 DB module TMF_TATA_bd PF12325.8 VBB29451.1 - 0.016 15.4 5.8 0.51 10.6 1.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding EzrA PF06160.12 VBB29451.1 - 0.04 12.1 0.3 0.055 11.6 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 VBB29451.1 - 0.041 14.4 0.1 0.1 13.1 0.1 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DP PF08781.10 VBB29452.1 - 6.4e-56 188.1 0.4 1.5e-55 186.9 0.4 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 VBB29452.1 - 1.6e-17 63.3 0.2 4e-17 62.0 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Noc2 PF03715.13 VBB29452.1 - 1.2 8.4 4.9 3.2 6.9 0.0 2.9 2 1 1 3 3 3 0 Noc2p family Cwf_Cwc_15 PF04889.12 VBB29453.1 - 0.0061 16.3 8.0 0.0063 16.3 8.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 VBB29453.1 - 0.08 13.3 14.9 0.11 12.9 14.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 VBB29453.1 - 0.093 12.6 1.5 0.084 12.7 1.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 VBB29453.1 - 0.17 11.2 9.1 0.16 11.3 9.1 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 VBB29453.1 - 0.22 11.5 3.3 0.2 11.7 3.3 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 VBB29453.1 - 0.39 10.4 1.4 0.47 10.1 1.4 1.2 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 VBB29453.1 - 1.4 8.5 5.8 1.2 8.7 5.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 VBB29453.1 - 8.8 5.3 16.3 11 5.1 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rad1 PF02144.16 VBB29456.1 - 2.4e-40 138.4 0.2 4.7e-40 137.4 0.2 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 VBB29456.1 - 0.0035 16.8 1.2 0.06 12.8 0.4 2.3 1 1 1 2 2 2 1 Rad9 Astacin PF01400.24 VBB29457.1 - 4.7e-73 244.9 0.0 7.6e-73 244.2 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 VBB29457.1 - 1.9e-08 34.7 10.2 5.5e-08 33.2 6.8 2.6 2 0 0 2 2 2 1 ShK domain-like Peptidase_M11 PF05548.11 VBB29457.1 - 0.046 12.9 0.2 0.07 12.3 0.2 1.2 1 0 0 1 1 1 0 Gametolysin peptidase M11 TRAP_beta PF05753.14 VBB29458.1 - 2.7e-51 173.5 0.0 3.8e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) ATP-synt_G PF04718.15 VBB29459.1 - 4.8e-16 59.4 0.0 6.3e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit LSM PF01423.22 VBB29460.1 - 9.4e-20 70.1 0.1 1.5e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 LSM domain Mss4 PF04421.13 VBB29460.1 - 2.1e-16 59.8 0.1 4.6e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Mss4 protein DUF2730 PF10805.8 VBB29460.1 - 0.059 13.5 0.5 4.7 7.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Flagellin_N PF00669.20 VBB29460.1 - 0.17 12.0 0.2 0.35 11.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Rab5ip PF07019.12 VBB29461.1 - 1.5e-13 51.2 8.4 2.7e-13 50.3 8.4 1.4 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GRIP PF01465.20 VBB29461.1 - 3.1e-12 46.2 0.0 7.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 GRIP domain BLOC1_2 PF10046.9 VBB29461.1 - 0.0015 18.7 4.8 0.0015 18.7 4.8 5.7 5 2 1 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 VBB29461.1 - 0.0083 16.4 24.3 0.0083 16.4 24.3 5.3 2 2 3 5 5 5 1 Autophagy protein 16 (ATG16) POTRA_2 PF08479.11 VBB29461.1 - 0.11 12.3 0.1 0.53 10.1 0.1 2.2 1 0 0 1 1 1 0 POTRA domain, ShlB-type Surfac_D-trimer PF09006.11 VBB29461.1 - 0.14 12.0 0.2 22 5.0 0.1 3.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF1843 PF08898.10 VBB29461.1 - 0.41 11.2 0.1 0.41 11.2 0.1 5.0 6 2 0 6 6 6 0 Domain of unknown function (DUF1843) SAB PF04382.13 VBB29461.1 - 1.1 9.3 5.5 2.9 8.0 2.7 3.1 2 0 0 2 2 2 0 SAB domain DUF1664 PF07889.12 VBB29461.1 - 1.8 8.7 33.6 0.17 12.0 1.7 5.9 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 VBB29461.1 - 3.1 8.2 64.5 0.31 11.5 21.6 5.1 2 1 2 4 4 4 0 Fez1 14-3-3 PF00244.20 VBB29462.1 - 1.7e-38 132.3 4.3 2.9e-38 131.6 4.3 1.4 1 0 0 1 1 1 1 14-3-3 protein DUF2856 PF11043.8 VBB29462.1 - 0.03 14.5 0.4 0.18 11.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) Pox_Ag35 PF03286.14 VBB29462.1 - 0.33 10.7 3.5 0.73 9.6 3.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Motile_Sperm PF00635.26 VBB29463.1 - 0.024 14.5 0.4 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DUF2750 PF11042.8 VBB29463.1 - 0.055 13.5 0.1 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2750) EGF PF00008.27 VBB29464.1 - 6.6e-11 42.3 37.8 3e-06 27.4 9.1 4.5 3 2 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 VBB29464.1 - 1.2e-08 35.1 44.6 0.00059 20.2 5.3 3.4 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 VBB29464.1 - 4e-07 30.4 40.7 0.0001 22.8 8.5 5.0 4 1 0 4 4 4 2 Human growth factor-like EGF EGF_CA PF07645.15 VBB29464.1 - 3.8e-05 23.8 9.6 3.8e-05 23.8 9.6 3.7 3 1 0 3 3 3 2 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 VBB29464.1 - 8.6e-05 22.8 23.7 0.12 12.7 6.4 3.5 3 0 0 3 3 3 3 Pvs28 EGF domain FXa_inhibition PF14670.6 VBB29464.1 - 0.012 15.9 31.1 1.1 9.6 8.3 3.7 1 1 2 3 3 3 0 Coagulation Factor Xa inhibitory site Syndecan PF01034.20 VBB29464.1 - 0.069 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain EGF_3 PF12947.7 VBB29464.1 - 0.099 12.9 34.6 0.34 11.1 7.5 3.8 2 1 1 3 3 3 0 EGF domain LapA_dom PF06305.11 VBB29464.1 - 0.84 9.5 3.2 1.2 9.0 3.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TED_complement PF07678.14 VBB29465.1 - 2.4e-102 342.2 1.3 4.5e-102 341.3 1.3 1.5 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 VBB29465.1 - 3.6e-29 100.4 3.0 2.7e-28 97.7 0.4 3.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 VBB29465.1 - 3.2e-26 92.3 7.1 1.1e-25 90.6 1.1 3.4 2 1 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 VBB29465.1 - 5.1e-22 77.9 0.2 1.8e-21 76.2 0.2 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG3 A2M_recep PF07677.14 VBB29465.1 - 4.4e-17 62.6 0.4 4.1e-16 59.5 0.0 3.0 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG2 PF01835.19 VBB29465.1 - 3.7e-16 59.4 0.0 2.4e-15 56.7 0.0 2.6 1 0 0 1 1 1 1 MG2 domain MG4 PF17789.1 VBB29465.1 - 2e-06 27.8 7.2 8.3e-05 22.7 0.1 4.7 4 0 0 4 4 4 1 Macroglobulin domain MG4 DUF559 PF04480.12 VBB29465.1 - 0.065 13.1 0.2 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF559) EIIC-GAT PF03611.14 VBB29466.1 - 0.036 13.2 0.3 0.049 12.7 0.3 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component DUF5300 PF17224.3 VBB29466.1 - 0.33 11.2 4.9 0.94 9.8 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) Innexin PF00876.18 VBB29467.1 - 3.7e-109 365.3 15.7 4.1e-109 365.1 15.7 1.0 1 0 0 1 1 1 1 Innexin Catalase-rel PF06628.12 VBB29467.1 - 0.091 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive DUF1098 PF06497.11 VBB29468.1 - 0.00073 20.0 0.4 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1098) Mog1 PF04603.12 VBB29468.1 - 0.3 11.4 2.1 0.54 10.6 0.2 2.0 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Ets PF00178.22 VBB29469.1 - 6.4e-31 106.7 3.0 1.4e-30 105.6 3.0 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 VBB29469.1 - 1.8e-14 53.5 0.1 3.5e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AA_permease_2 PF13520.6 VBB29470.1 - 6e-18 64.9 7.5 6.3e-18 64.8 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 VBB29470.1 - 2.7e-09 36.1 7.7 2.8e-09 36.1 7.7 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 VBB29470.1 - 0.00046 19.3 5.3 0.00052 19.2 5.3 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family PMP22_Claudin PF00822.20 VBB29470.1 - 0.006 16.5 0.8 0.0078 16.1 0.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1616 PF07760.11 VBB29470.1 - 0.16 11.3 0.3 0.25 10.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) SSF PF00474.17 VBB29471.1 - 1.3e-23 83.5 29.9 3.6e-21 75.5 21.9 2.3 2 0 0 2 2 2 2 Sodium:solute symporter family G-alpha PF00503.20 VBB29472.1 - 2.2e-125 418.5 1.3 2.6e-125 418.3 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB29472.1 - 8e-18 64.5 0.3 6.4e-13 48.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB29472.1 - 0.00011 21.7 2.0 0.018 14.4 0.3 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 VBB29472.1 - 0.00034 20.8 0.2 1 9.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 VBB29472.1 - 0.0026 17.2 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 VBB29472.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 VBB29472.1 - 0.17 12.0 0.1 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PAN_1 PF00024.26 VBB29473.1 - 2.7e-38 129.8 38.8 1.7e-13 50.4 6.3 4.4 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 VBB29473.1 - 0.00023 20.9 0.6 0.00023 20.9 0.6 4.9 6 1 0 6 6 6 2 PAN-like domain PAN_4 PF14295.6 VBB29473.1 - 0.13 12.2 0.2 0.13 12.2 0.2 4.5 4 1 0 4 4 4 0 PAN domain Trehalase PF01204.18 VBB29474.1 - 6.5e-114 381.6 0.6 8.1e-114 381.2 0.6 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 VBB29474.1 - 2.6e-05 23.2 0.2 4.9e-05 22.3 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain GDE_C PF06202.14 VBB29474.1 - 0.0027 16.7 0.2 0.015 14.3 0.2 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 VBB29474.1 - 0.0064 15.8 0.1 0.049 12.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain LapA_dom PF06305.11 VBB29474.1 - 0.87 9.4 3.4 2.9 7.8 1.3 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Citrate_synt PF00285.21 VBB29475.1 - 7.3e-104 347.7 0.0 9.3e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF4131 PF13567.6 VBB29476.1 - 0.025 14.2 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) zf-LITAF-like PF10601.9 VBB29476.1 - 0.6 10.4 5.2 5.2 7.4 5.6 1.9 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain MMS1_N PF10433.9 VBB29477.1 - 5.7e-149 496.9 0.0 1.9e-147 491.8 0.0 2.8 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 VBB29477.1 - 1.8e-23 83.4 0.1 7.4e-23 81.4 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region START PF01852.19 VBB29480.1 - 4.2e-13 49.2 0.0 4.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 START domain CBM_14 PF01607.24 VBB29481.1 - 4.9e-175 567.7 289.4 9.5e-12 44.9 4.8 27.5 27 0 0 27 27 27 26 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 VBB29481.1 - 0.038 12.1 1.0 2.6 6.0 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Pkinase PF00069.25 VBB29482.1 - 2.5e-19 69.7 0.4 3.4e-11 43.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29482.1 - 3.3e-11 43.0 0.7 4.5e-06 26.2 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase TTR-52 PF01060.23 VBB29483.1 - 1.7e-19 70.3 0.1 2.3e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Transthyretin-like family ubiquitin PF00240.23 VBB29484.1 - 2.2e-14 52.9 0.0 6e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 VBB29484.1 - 1.3e-05 24.9 0.1 3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BAG6 PF12057.8 VBB29484.1 - 0.0002 21.0 0.3 0.0002 21.0 0.3 2.8 3 0 0 3 3 3 1 BCL2-associated athanogene 6 Ubiquitin_4 PF18036.1 VBB29484.1 - 0.14 12.2 0.0 5.4 7.1 0.0 2.6 1 1 0 1 1 1 0 Ubiquitin-like domain CCDC53 PF10152.9 VBB29484.1 - 0.87 10.0 8.4 0.071 13.5 0.5 2.9 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex TIP41 PF04176.13 VBB29485.1 - 7.1e-57 191.6 0.0 9.7e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family LBP_BPI_CETP_C PF02886.17 VBB29486.1 - 1e-33 116.8 0.0 1.8e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain ASXH PF13919.6 VBB29487.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Asx homology domain COBRA1 PF06209.13 VBB29488.1 - 1.2e-85 288.1 4.6 1.6e-85 287.8 4.6 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) VHS PF00790.19 VBB29489.1 - 6.7e-39 133.0 0.2 2.2e-38 131.3 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 VBB29489.1 - 3e-18 65.9 2.7 1.2e-17 64.0 2.7 2.1 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 VBB29489.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 ENTH domain SAC3_GANP PF03399.16 VBB29489.1 - 0.015 14.7 0.6 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 SAC3/GANP family CorA PF01544.18 VBB29489.1 - 0.17 11.2 3.3 0.2 10.9 0.1 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein RUN PF02759.19 VBB29490.1 - 6.1e-24 84.5 0.1 2.4e-23 82.6 0.1 2.1 1 0 0 1 1 1 1 RUN domain CNH PF00780.22 VBB29490.1 - 6.3e-06 26.0 1.0 3e-05 23.8 0.2 2.5 2 1 0 2 2 2 1 CNH domain Vps39_2 PF10367.9 VBB29490.1 - 0.00041 20.8 1.2 0.00041 20.8 1.2 4.0 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_2 PF07719.17 VBB29490.1 - 0.039 14.1 0.3 0.48 10.7 0.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4883 PF16224.5 VBB29490.1 - 0.06 13.6 0.1 0.24 11.6 0.1 2.1 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) YdjO PF14169.6 VBB29490.1 - 0.1 12.4 1.5 0.34 10.7 0.3 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO B9-C2 PF07162.11 VBB29490.1 - 0.12 12.6 0.2 0.79 9.9 0.0 2.4 3 0 0 3 3 3 0 Ciliary basal body-associated, B9 protein Thioredoxin PF00085.20 VBB29491.1 - 1.5e-63 211.3 0.3 2.1e-31 108.0 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 VBB29491.1 - 4.1e-46 157.2 5.7 3.2e-39 134.7 2.4 3.6 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 VBB29491.1 - 7.7e-13 48.9 0.9 3.3e-05 24.3 0.2 4.2 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 VBB29491.1 - 1e-09 38.6 0.9 0.00047 20.4 0.1 4.6 3 2 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 VBB29491.1 - 5.1e-09 35.9 0.1 0.023 14.1 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 VBB29491.1 - 7.3e-09 35.6 0.5 0.0013 18.7 0.0 4.1 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 VBB29491.1 - 1.8e-07 30.9 0.5 0.0043 16.8 0.1 3.6 4 0 0 4 4 4 2 Redoxin Thioredoxin_7 PF13899.6 VBB29491.1 - 2.1e-07 31.0 2.4 0.0061 16.7 0.0 3.8 5 0 0 5 5 5 2 Thioredoxin-like Glutaredoxin PF00462.24 VBB29491.1 - 0.0002 21.5 0.3 0.011 16.0 0.1 2.9 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 VBB29491.1 - 0.00074 19.4 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 VBB29491.1 - 0.014 15.1 0.4 0.78 9.5 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 VBB29491.1 - 0.12 12.5 0.5 5.6 7.1 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin C_tripleX PF02363.19 VBB29492.1 - 0.042 14.1 15.3 0.042 14.1 15.3 8.8 7 0 0 7 7 7 0 Cysteine rich repeat DUF3439 PF11921.8 VBB29492.1 - 6.9 6.7 11.9 17 5.4 11.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ST7 PF04184.12 VBB29493.1 - 1.5e-249 828.9 7.3 4.7e-249 827.3 7.3 1.6 1 1 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 VBB29493.1 - 0.00014 22.3 0.1 0.00075 20.0 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29493.1 - 0.0016 19.1 6.8 0.61 11.1 0.1 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29493.1 - 0.014 15.5 0.0 0.37 11.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 VBB29493.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_19 PF14559.6 VBB29493.1 - 0.025 15.1 1.7 2.3 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB29493.1 - 0.028 14.2 0.1 25 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 VBB29493.1 - 0.062 14.0 0.6 0.3 11.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Mon2_C PF16206.5 VBB29494.1 - 3.3e-162 541.5 6.6 3.3e-162 541.5 6.6 2.6 2 1 0 2 2 2 1 C-terminal region of Mon2 protein DCB PF16213.5 VBB29494.1 - 7.8e-63 211.3 9.5 7.8e-63 211.3 9.5 2.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 VBB29494.1 - 3.8e-42 143.9 1.9 3.8e-42 143.9 1.9 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 VBB29494.1 - 5.9e-06 26.0 0.1 5.9e-06 26.0 0.1 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) HEAT PF02985.22 VBB29494.1 - 0.0029 17.7 3.2 4.5 7.8 0.1 5.7 5 0 0 5 5 5 1 HEAT repeat AstB PF04996.12 VBB29494.1 - 0.055 12.1 0.2 0.1 11.3 0.2 1.3 1 0 0 1 1 1 0 Succinylarginine dihydrolase Pkinase_Tyr PF07714.17 VBB29496.1 - 1.1e-56 192.0 0.0 1.7e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB29496.1 - 7.1e-22 78.0 0.0 1.4e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Nucleoporin_C PF03177.14 VBB29497.1 - 1.8e-09 36.9 0.9 4e-09 35.8 0.9 1.5 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 VBB29497.1 - 0.0009 18.1 0.1 0.0039 16.0 0.0 1.9 2 0 0 2 2 2 1 Nup133 N terminal like Suv3_N PF18114.1 VBB29498.1 - 2.2e-34 118.1 0.1 8.6e-34 116.2 0.0 2.1 2 0 0 2 2 2 1 Suv3 helical N-terminal domain SUV3_C PF12513.8 VBB29498.1 - 1.5e-15 56.8 1.0 4.2e-15 55.4 1.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 VBB29498.1 - 4.3e-11 42.5 0.1 1.3e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 VBB29498.1 - 2.5e-08 34.2 0.0 6.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB29498.1 - 0.036 13.8 0.1 0.14 11.9 0.0 2.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase Mu-like_Com PF10122.9 VBB29499.1 - 0.014 14.8 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com PriA_CRR PF18319.1 VBB29499.1 - 0.045 13.7 1.7 0.056 13.4 0.3 2.0 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain ACOX PF01756.19 VBB29500.1 - 1.4e-31 109.5 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA oxidase JUPITER PF17054.5 VBB29500.1 - 0.17 11.4 0.0 0.2 11.1 0.0 1.0 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Pullulanase_N2 PF17967.1 VBB29503.1 - 0.54 11.1 4.0 0.35 11.7 0.9 2.5 2 0 0 2 2 2 0 Pullulanase N2 domain Laps PF10169.9 VBB29504.1 - 1.6e-16 61.0 16.6 4.2e-13 50.0 16.6 2.0 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 VBB29504.1 - 1.3e-05 25.3 5.1 1.3e-05 25.3 5.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Ribosomal_S3_C PF00189.20 VBB29505.1 - 0.0066 16.9 0.0 0.008 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain BACK PF07707.15 VBB29507.1 - 3.6e-06 27.0 4.1 5.7e-06 26.4 0.1 3.1 4 1 0 4 4 4 1 BTB And C-terminal Kelch EGF_2 PF07974.13 VBB29508.1 - 1.1e-18 67.2 122.5 2.6e-05 24.5 7.6 7.5 7 0 0 7 7 7 6 EGF-like domain Cadherin PF00028.17 VBB29508.1 - 1.6e-07 31.7 0.2 1.1e-06 29.0 0.0 2.6 2 0 0 2 2 2 1 Cadherin domain EGF PF00008.27 VBB29508.1 - 0.0007 19.9 94.7 0.0013 19.0 7.3 7.8 7 0 0 7 7 7 5 EGF-like domain Cpn10 PF00166.21 VBB29509.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit Vps8 PF12816.7 VBB29510.1 - 3.7e-43 147.4 0.1 7.9e-43 146.3 0.1 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 ANAPC4_WD40 PF12894.7 VBB29510.1 - 9.6e-06 25.8 0.0 0.0012 19.1 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4158 PF13700.6 VBB29510.1 - 0.0095 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) Pkinase_Tyr PF07714.17 VBB29511.1 - 5e-38 130.9 0.0 7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB29511.1 - 5.2e-38 130.9 0.0 8.7e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 VBB29511.1 - 2.9e-12 45.9 0.1 6e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Haspin_kinase PF12330.8 VBB29511.1 - 0.032 13.2 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Defensin_3 PF08131.11 VBB29511.1 - 0.1 12.8 1.5 2.9 8.2 0.1 2.8 2 0 0 2 2 2 0 Defensin-like peptide family APH PF01636.23 VBB29511.1 - 0.12 12.2 0.0 0.64 9.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 VBB29511.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Activin_recp PF01064.23 VBB29511.1 - 0.51 11.5 7.5 1.3 10.2 7.5 1.7 1 0 0 1 1 1 0 Activin types I and II receptor domain CH PF00307.31 VBB29512.1 - 4.2e-11 43.0 0.9 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB29512.1 - 0.0061 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Borrelia_P83 PF05262.11 VBB29512.1 - 0.87 8.0 23.3 1.1 7.6 22.3 1.6 1 1 0 1 1 1 0 Borrelia P83/100 protein Spc7 PF08317.11 VBB29512.1 - 5.8 5.7 32.1 0.53 9.1 14.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-MYND PF01753.18 VBB29513.1 - 0.00012 22.1 20.6 0.00031 20.8 20.6 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 VBB29513.1 - 0.93 9.4 6.7 2.5 8.1 6.7 1.8 1 1 0 1 1 1 0 HIT zinc finger 7tm_1 PF00001.21 VBB29515.1 - 1.1e-23 83.9 10.6 1.5e-23 83.5 10.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB29515.1 - 0.00012 21.8 0.5 0.00012 21.8 0.5 3.1 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx Iso_dh PF00180.20 VBB29516.1 - 6.7e-73 245.8 0.0 8.7e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RPAP2_Rtr1 PF04181.13 VBB29517.1 - 1.2e-19 70.4 1.4 1.2e-19 70.4 1.4 2.0 2 0 0 2 2 2 1 Rtr1/RPAP2 family Spt5_N PF11942.8 VBB29517.1 - 0.013 16.4 3.4 0.033 15.1 3.4 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4798 PF16055.5 VBB29517.1 - 0.017 15.3 0.5 0.049 13.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Nop16 PF09420.10 VBB29518.1 - 2e-21 77.0 12.0 3.5e-14 53.4 1.6 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Acyl-CoA_dh_1 PF00441.24 VBB29520.1 - 2.3e-71 238.9 4.7 4e-43 147.2 0.8 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 VBB29520.1 - 5.8e-37 126.8 0.3 1.5e-24 86.8 0.0 3.4 2 1 1 3 3 3 3 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 VBB29520.1 - 3e-35 120.3 1.2 1.2e-23 83.1 0.0 3.1 2 1 1 3 3 3 2 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 VBB29520.1 - 3.6e-28 98.5 1.7 5.8e-16 59.0 0.5 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 VBB29520.1 - 0.00093 18.9 0.0 0.004 16.9 0.0 2.0 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal OsmC PF02566.19 VBB29520.1 - 0.044 14.3 0.1 9.1 6.8 0.0 2.7 2 0 0 2 2 2 0 OsmC-like protein Phage_TTP_11 PF16460.5 VBB29520.1 - 0.11 12.4 0.0 18 5.2 0.0 2.9 2 0 0 2 2 2 0 Phage tail tube, TTP, lambda-like DREPP PF05558.12 VBB29520.1 - 0.15 11.9 0.4 3.6 7.4 0.2 2.2 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide C2 PF00168.30 VBB29522.1 - 6.1e-06 26.5 0.0 1.5e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 VBB29522.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain RGS PF00615.19 VBB29523.1 - 3e-36 124.3 2.3 4.9e-36 123.6 2.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain APC_u15 PF16636.5 VBB29523.1 - 0.13 12.7 1.2 0.38 11.2 0.4 2.3 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 zf-C3HC4_3 PF13920.6 VBB29524.1 - 6.3e-06 26.0 0.8 1e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB29524.1 - 1.6e-05 24.7 0.4 2.9e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB29524.1 - 8.7e-05 22.8 0.5 0.00016 21.9 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain Pex2_Pex12 PF04757.14 VBB29524.1 - 0.00086 19.0 3.7 0.0012 18.5 3.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_UBOX PF13445.6 VBB29524.1 - 0.016 15.2 1.3 0.03 14.3 1.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 VBB29524.1 - 0.026 14.8 0.6 0.079 13.3 0.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 VBB29524.1 - 0.049 13.8 1.3 0.12 12.5 1.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 VBB29524.1 - 0.078 12.9 5.0 0.51 10.3 5.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB29524.1 - 0.13 12.2 1.3 0.3 11.1 1.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 VBB29524.1 - 0.21 11.5 1.3 1.7 8.6 1.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHR PF08005.12 VBB29525.1 - 7.4e-17 62.4 0.0 8.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 PHR domain Globin PF00042.22 VBB29526.1 - 0.01 16.4 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 0 Globin DUF3658 PF12395.8 VBB29526.1 - 0.1 12.5 0.6 0.39 10.6 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function ESPR PF13018.6 VBB29526.1 - 0.14 12.0 1.0 0.25 11.2 1.0 1.4 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system DUF1414 PF07208.11 VBB29526.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Pro_isomerase PF00160.21 VBB29527.1 - 1.7e-50 171.4 0.2 2e-50 171.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDEase_I PF00233.19 VBB29529.1 - 1.2e-66 224.9 0.1 3.3e-66 223.4 0.1 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Dynamin_M PF01031.20 VBB29530.1 - 6.7e-106 353.7 1.8 6.7e-106 353.7 1.8 2.2 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 VBB29530.1 - 4.5e-56 189.5 0.0 1.3e-55 188.1 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 VBB29530.1 - 4e-25 87.8 1.2 1.3e-24 86.2 1.2 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 VBB29530.1 - 3e-10 40.5 0.3 6.4e-10 39.5 0.3 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 VBB29530.1 - 0.00022 21.3 0.0 0.00082 19.4 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase OSTMP1 PF09777.9 VBB29530.1 - 0.0086 15.5 0.4 0.015 14.7 0.4 1.3 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor RasGAP PF00616.19 VBB29530.1 - 0.066 12.9 0.4 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase SANTA PF09133.10 VBB29531.1 - 2.7e-37 127.1 0.0 5.4e-20 71.7 0.0 2.7 2 0 0 2 2 2 2 SANTA (SANT Associated) Myb_DNA-bind_6 PF13921.6 VBB29531.1 - 0.00035 20.8 0.2 0.0025 18.0 0.2 2.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 VBB29531.1 - 0.00038 20.6 0.3 0.001 19.2 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-CCCH_4 PF18044.1 VBB29532.1 - 5e-08 32.6 5.4 9.5e-08 31.7 5.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 VBB29532.1 - 0.00047 20.0 4.5 0.00083 19.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB29532.1 - 0.004 17.2 7.4 0.0084 16.1 7.4 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 VBB29532.1 - 0.0074 17.0 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 Torus domain RWD PF05773.22 VBB29532.1 - 0.012 15.9 0.7 0.027 14.8 0.0 2.0 2 0 0 2 2 2 0 RWD domain zf-CCCH_2 PF14608.6 VBB29532.1 - 0.26 11.8 6.3 0.53 10.8 6.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RNase_PH PF01138.21 VBB29533.1 - 5e-24 85.3 0.6 8.7e-24 84.5 0.6 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TGF_beta PF00019.20 VBB29534.1 - 2.6e-16 60.5 0.5 4.7e-16 59.7 0.5 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain DC_STAMP PF07782.13 VBB29535.1 - 2e-19 70.1 8.3 7.3e-10 39.0 0.1 3.2 3 1 1 4 4 4 2 DC-STAMP-like protein CEBP_ZZ PF16366.5 VBB29535.1 - 0.94 9.8 8.1 2.3 8.5 8.1 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TGF_beta PF00019.20 VBB29536.1 - 2.7e-13 50.8 1.5 6.2e-13 49.6 1.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain PP_kinase PF02503.17 VBB29536.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase middle domain IL28A PF15177.6 VBB29537.1 - 0.0037 17.1 0.1 0.0046 16.8 0.1 1.2 1 0 0 1 1 1 1 Interleukin-28A FapA PF03961.13 VBB29537.1 - 0.016 13.8 0.6 0.018 13.7 0.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 VBB29537.1 - 0.017 15.5 3.7 0.021 15.2 3.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SPECT1 PF18680.1 VBB29537.1 - 0.048 13.3 3.6 0.059 13.0 3.6 1.1 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 Hemagglutinin PF00509.18 VBB29537.1 - 0.054 11.9 1.0 0.067 11.6 1.0 1.1 1 0 0 1 1 1 0 Haemagglutinin RmuC PF02646.16 VBB29537.1 - 0.13 11.4 5.0 0.81 8.8 1.1 2.0 1 1 1 2 2 2 0 RmuC family CLZ PF16526.5 VBB29537.1 - 0.39 11.1 3.3 2.8 8.3 1.7 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mito_carr PF00153.27 VBB29539.1 - 1.1e-58 195.2 0.5 1.3e-18 66.6 0.3 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein TraB PF01963.17 VBB29540.1 - 2.8e-25 89.7 0.1 4.6e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 TraB family ELO PF01151.18 VBB29541.1 - 5e-55 186.7 26.7 6.3e-55 186.4 26.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4229 PF14012.6 VBB29541.1 - 2.5 8.3 6.9 9.9 6.4 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) ELO PF01151.18 VBB29542.1 - 4.9e-51 173.7 27.5 5.8e-51 173.4 27.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Astacin PF01400.24 VBB29543.1 - 5.3e-59 199.1 0.0 3.3e-57 193.2 0.0 3.0 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 VBB29543.1 - 0.00017 21.5 2.2 0.2 11.5 0.0 3.5 4 0 0 4 4 4 2 Matrixin Peptidase_M66 PF10462.9 VBB29543.1 - 0.0026 16.8 1.1 0.044 12.7 0.2 2.4 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_4 PF13583.6 VBB29543.1 - 0.005 16.5 0.0 0.005 16.5 0.0 2.6 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like KH_1 PF00013.29 VBB29544.1 - 4.4e-05 23.2 0.5 8.3e-05 22.3 0.5 1.4 1 0 0 1 1 1 1 KH domain STAR_dimer PF16544.5 VBB29544.1 - 0.083 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein CUB PF00431.20 VBB29545.1 - 1.7e-13 50.9 0.0 3.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 CUB domain Fringe PF02434.16 VBB29546.1 - 5e-78 262.0 0.0 5.9e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Glyco_transf_21 PF13506.6 VBB29546.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 21 Btz PF09405.10 VBB29547.1 - 7.8e-08 32.6 6.1 7.8e-08 32.6 6.1 1.9 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding RhoGEF PF00621.20 VBB29548.1 - 4.5e-20 72.7 5.1 4.5e-20 72.7 5.1 1.9 2 0 0 2 2 2 1 RhoGEF domain Peptidase_M1 PF01433.20 VBB29550.1 - 4.7e-13 49.2 0.1 1.2e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 VBB29550.1 - 4.3e-05 23.8 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Arteri_Gl PF00951.18 VBB29550.1 - 0.052 13.4 1.2 1.6 8.6 2.8 2.2 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein ZU5 PF00791.20 VBB29551.1 - 5.5e-20 71.5 0.0 1.2e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain UPA PF17217.3 VBB29551.1 - 1.8e-15 57.1 0.0 3.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 UPA domain Death PF00531.22 VBB29551.1 - 2.8e-11 43.4 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.19 VBB29551.1 - 3.2e-06 27.3 24.4 0.00014 22.0 10.5 3.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain UPF0560 PF10577.9 VBB29551.1 - 2.2e-05 23.2 0.1 3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 Stevor PF17410.2 VBB29551.1 - 0.063 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Thioredoxin_8 PF13905.6 VBB29552.1 - 4.4e-10 39.8 0.2 6.3e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 VBB29552.1 - 0.0056 16.4 0.5 0.068 12.9 0.1 2.0 1 1 1 2 2 2 1 Redoxin PARG_cat PF05028.14 VBB29553.1 - 9.2e-122 406.5 0.0 1.4e-121 406.0 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) E1_dh PF00676.20 VBB29554.1 - 1.3e-70 237.7 0.0 2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 VBB29554.1 - 2.4e-64 216.3 0.0 3.9e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 VBB29554.1 - 2.9e-49 166.7 0.0 6.3e-49 165.6 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 VBB29554.1 - 5.3e-17 61.1 0.7 5.3e-17 61.1 0.7 3.2 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus UQ_con PF00179.26 VBB29555.1 - 2.6e-53 179.4 0.1 3.2e-53 179.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB29555.1 - 0.00096 18.9 0.0 0.0015 18.2 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 VBB29555.1 - 0.0033 17.7 0.0 0.006 16.8 0.0 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 VBB29555.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 VBB29555.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 PTB PF08416.13 VBB29558.1 - 3.8e-09 36.8 0.0 1.3e-08 35.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotyrosine-binding domain THAP PF05485.12 VBB29560.1 - 0.00012 22.9 0.2 0.00019 22.3 0.2 1.4 1 0 0 1 1 1 1 THAP domain Ras PF00071.22 VBB29562.1 - 1.7e-23 83.0 1.0 2e-23 82.8 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB29562.1 - 1e-10 41.9 0.1 1.5e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 VBB29562.1 - 1.5e-05 25.0 0.1 2.5e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 VBB29562.1 - 0.0001 22.1 0.4 0.00014 21.6 0.4 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 VBB29562.1 - 0.012 16.1 0.0 0.015 15.8 0.0 1.3 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 VBB29562.1 - 0.03 14.2 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 VBB29562.1 - 0.036 14.6 0.1 0.072 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain I-set PF07679.16 VBB29563.1 - 4.8e-39 132.3 0.0 6.6e-13 48.5 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB29563.1 - 2.7e-25 88.8 0.0 5.1e-09 36.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB29563.1 - 2.7e-19 69.1 0.0 1.6e-06 28.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB29563.1 - 1.7e-12 47.5 0.0 0.0024 18.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 VBB29563.1 - 3e-11 43.5 0.0 0.00028 21.0 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 VBB29563.1 - 2e-06 27.2 0.0 0.13 11.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 VBB29563.1 - 3.5e-05 24.1 0.9 1.3 9.5 0.0 3.9 3 2 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 VBB29563.1 - 4.8e-05 23.5 0.1 1.8 8.9 0.0 4.3 3 2 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 VBB29563.1 - 0.00028 20.9 0.1 2.2 8.4 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 VBB29563.1 - 0.0011 19.1 0.1 6.4 7.0 0.0 3.3 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 VBB29563.1 - 0.018 15.1 0.1 0.83 9.6 0.0 2.9 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain C2-set PF05790.15 VBB29563.1 - 0.051 13.8 0.2 5.2 7.3 0.1 3.4 4 1 0 4 4 4 0 Immunoglobulin C2-set domain GRDP-like PF07173.12 VBB29564.1 - 1.3e-51 175.0 8.7 2.8e-39 135.0 5.6 2.5 1 1 1 2 2 2 2 Glycine-rich domain-containing protein-like Nfu_N PF08712.11 VBB29565.1 - 4.9e-29 100.2 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 VBB29565.1 - 7.1e-25 87.0 0.2 1.3e-24 86.1 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain DUF4535 PF15054.6 VBB29565.1 - 4.7e-06 26.2 0.0 2.2e-05 24.1 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4535) FKBP_C PF00254.28 VBB29566.1 - 4.3e-34 116.7 0.0 5e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase 2H-phosphodiest PF08975.10 VBB29566.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) CDP-OH_P_transf PF01066.21 VBB29568.1 - 2e-14 54.1 0.6 2e-14 54.1 0.6 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Nucleoside_tran PF01733.18 VBB29569.1 - 2.6e-48 165.0 26.1 1.2e-34 120.1 12.8 2.6 3 0 0 3 3 3 2 Nucleoside transporter Abhydrolase_9_N PF15420.6 VBB29569.1 - 3.5 7.6 8.2 2 8.4 0.2 3.3 2 2 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus LLGL PF08366.13 VBB29570.1 - 2.2e-26 92.2 0.1 1.6e-24 86.2 0.0 3.5 2 1 0 2 2 2 1 LLGL2 ANAPC4_WD40 PF12894.7 VBB29570.1 - 0.00036 20.8 0.0 0.43 10.9 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 VBB29570.1 - 0.025 13.3 0.1 0.63 8.7 0.0 2.6 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 VBB29570.1 - 0.071 14.0 2.3 11 7.1 0.1 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat SMC_N PF02463.19 VBB29573.1 - 7.3e-69 231.6 8.6 4.9e-68 228.8 8.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 VBB29573.1 - 2.9e-11 43.7 1.3 2e-10 41.0 0.1 2.9 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 VBB29573.1 - 4.4e-09 36.6 11.0 4.4e-05 23.4 0.1 4.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 VBB29573.1 - 3.8e-05 23.3 0.0 0.00013 21.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 VBB29573.1 - 0.11 13.0 114.8 0.012 16.1 48.8 6.8 2 2 1 3 3 3 0 AAA domain ABC_tran PF00005.27 VBB29573.1 - 0.34 11.4 25.7 0.58 10.7 0.0 5.7 3 2 0 3 3 3 0 ABC transporter DUF1488 PF07369.11 VBB29573.1 - 0.58 10.2 4.5 3.6 7.6 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1488) ANAPC5 PF12862.7 VBB29573.1 - 6.3 6.9 5.5 35 4.5 0.3 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 DB PF01682.19 VBB29575.1 - 6.2e-20 71.4 14.0 1e-19 70.7 14.0 1.3 1 0 0 1 1 1 1 DB module DUF3140 PF11338.8 VBB29576.1 - 0.068 13.6 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) RDD PF06271.12 VBB29578.1 - 1.8e-09 37.9 1.2 1.1e-08 35.4 1.2 2.0 1 1 0 1 1 1 1 RDD family Snapin_Pallidin PF14712.6 VBB29579.1 - 3.2e-23 82.0 0.7 4.3e-23 81.5 0.7 1.2 1 0 0 1 1 1 1 Snapin/Pallidin Prefoldin PF02996.17 VBB29579.1 - 0.00082 19.3 0.8 0.48 10.3 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit CENP-H PF05837.12 VBB29579.1 - 0.0044 17.4 0.2 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF4460 PF14687.6 VBB29579.1 - 0.017 15.2 0.5 0.022 14.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF3540 PF12059.8 VBB29579.1 - 0.023 14.5 0.5 0.052 13.4 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) Fib_alpha PF08702.10 VBB29579.1 - 0.043 14.0 2.8 0.071 13.3 2.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-ZPR1 PF03367.13 VBB29579.1 - 0.21 11.4 0.3 7.5 6.4 0.0 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain CLZ PF16526.5 VBB29579.1 - 0.7 10.3 2.9 4.5 7.7 0.2 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RPN1_RPN2_N PF17781.1 VBB29580.1 - 2.5e-113 378.6 0.8 5e-113 377.6 0.8 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 VBB29580.1 - 3.2e-29 100.7 0.2 6.2e-29 99.8 0.2 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 VBB29580.1 - 1.4e-11 44.2 18.7 6.1e-05 23.3 0.0 7.7 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 VBB29580.1 - 0.0035 17.7 0.1 1.6 9.2 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats AAA_33 PF13671.6 VBB29581.1 - 4.1e-25 88.6 0.1 9e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 VBB29581.1 - 2.5e-13 50.2 0.1 5.4e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 SPRY domain SAP PF02037.27 VBB29581.1 - 2.8e-06 26.9 0.7 2.8e-06 26.9 0.7 2.0 2 0 0 2 2 2 1 SAP domain AAA_22 PF13401.6 VBB29581.1 - 0.0034 17.7 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 VBB29581.1 - 0.0038 17.7 0.3 0.022 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB29581.1 - 0.012 16.0 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 VBB29581.1 - 0.043 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 VBB29581.1 - 0.051 13.3 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 VBB29581.1 - 0.065 13.3 0.2 0.51 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 VBB29581.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ELO PF01151.18 VBB29582.1 - 5.3e-32 111.3 10.7 6.6e-32 111.0 10.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Phage_holin_Dp1 PF16938.5 VBB29582.1 - 0.2 11.9 3.3 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 Putative phage holin Dp-1 DUF5337 PF17272.2 VBB29582.1 - 0.46 10.3 9.8 0.64 9.9 2.4 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5337) MMS19_N PF14500.6 VBB29583.1 - 1.6e-44 152.5 2.6 1.6e-44 152.5 2.6 2.8 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 VBB29583.1 - 9.7e-10 38.1 10.0 5.3e-09 35.7 5.0 3.3 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal F-box-like PF12937.7 VBB29584.1 - 1.5e-05 24.8 2.6 1.9e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 VBB29584.1 - 0.00019 21.2 0.0 0.00019 21.2 0.0 3.3 4 0 0 4 4 4 1 F-box domain F-box-like_2 PF13013.6 VBB29584.1 - 0.052 13.5 2.8 0.15 12.0 0.0 2.6 2 1 0 2 2 2 0 F-box-like domain DUF2992 PF11208.8 VBB29584.1 - 0.061 13.6 0.1 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Gelsolin PF00626.22 VBB29585.1 - 3.6e-61 203.0 8.0 1.3e-13 50.6 0.0 6.6 6 1 0 6 6 6 5 Gelsolin repeat ANAPC5 PF12862.7 VBB29586.1 - 3.3e-12 46.3 6.5 2.9e-10 40.1 0.8 4.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 VBB29586.1 - 1.5e-07 31.1 4.6 1.5e-07 31.1 4.6 3.2 3 1 0 3 3 3 1 MalT-like TPR region T6SS_VasJ PF16989.5 VBB29586.1 - 0.0021 17.6 2.6 0.28 10.6 0.3 2.7 2 1 0 2 2 2 2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_12 PF13424.6 VBB29586.1 - 0.0091 16.3 1.7 9.8 6.5 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29586.1 - 0.026 14.6 0.0 4.4 7.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 VBB29586.1 - 0.1 12.3 4.4 5.9 6.6 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 VBB29586.1 - 0.46 11.4 3.7 32 5.7 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29586.1 - 1.8 8.9 5.2 9.3 6.6 0.2 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.22 VBB29587.1 - 1.7e-52 177.3 0.0 2e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB29587.1 - 3.8e-20 72.3 0.0 5.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB29587.1 - 9.2e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB29587.1 - 1.3e-05 25.2 1.6 0.025 14.5 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 VBB29587.1 - 6.9e-05 22.7 1.2 0.00048 20.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 VBB29587.1 - 8.5e-05 22.2 0.2 0.00031 20.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB29587.1 - 0.00036 20.6 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB29587.1 - 0.00071 19.1 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 VBB29587.1 - 0.0019 17.4 0.0 0.18 10.9 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 VBB29587.1 - 0.032 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 VBB29587.1 - 0.07 13.5 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 VBB29587.1 - 0.12 12.0 0.4 0.26 10.9 0.4 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 VBB29587.1 - 0.14 11.9 0.4 0.82 9.4 0.1 2.0 1 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 VBB29588.1 - 1.6e-07 31.8 2.1 8e-07 29.6 2.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB29588.1 - 0.0037 17.6 0.3 0.47 11.2 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 VBB29588.1 - 0.041 14.5 0.1 0.1 13.2 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF356 PF04009.12 VBB29588.1 - 0.045 14.0 0.2 0.07 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF356) BRO1 PF03097.18 VBB29589.1 - 2.8e-104 349.0 6.1 2.8e-104 349.0 6.1 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 VBB29589.1 - 6.3e-77 258.8 20.7 2.2e-76 257.0 11.9 2.6 3 0 0 3 3 3 2 ALIX V-shaped domain binding to HIV GPP34 PF05719.11 VBB29589.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) FLYWCH PF04500.16 VBB29590.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.9 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C4 PF00105.18 VBB29592.1 - 1.2e-31 109.0 15.9 1.8e-31 108.4 15.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PSK_trans_fac PF07704.11 VBB29592.1 - 0.0021 18.8 0.0 0.0033 18.1 0.0 1.3 1 0 0 1 1 1 1 Rv0623-like transcription factor PAN_3 PF08277.12 VBB29592.1 - 0.0056 16.5 0.5 0.012 15.4 0.5 1.5 1 0 0 1 1 1 1 PAN-like domain C1_2 PF03107.16 VBB29592.1 - 0.048 14.0 0.7 0.048 14.0 0.7 2.3 2 0 0 2 2 2 0 C1 domain Androgen_recep PF02166.16 VBB29593.1 - 0.002 17.0 0.2 0.0022 16.9 0.2 1.1 1 0 0 1 1 1 1 Androgen receptor SelP_N PF04592.14 VBB29593.1 - 0.044 13.2 14.1 0.06 12.7 14.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 VBB29593.1 - 0.25 9.8 1.5 0.3 9.6 1.5 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_1 PF00170.21 VBB29594.1 - 0.0066 16.5 2.5 0.029 14.5 2.2 2.4 1 1 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 VBB29594.1 - 0.0067 16.2 2.4 0.023 14.4 2.4 1.9 1 0 0 1 1 1 1 Septum formation initiator Fzo_mitofusin PF04799.13 VBB29594.1 - 0.031 13.8 3.3 0.082 12.5 3.3 1.6 1 0 0 1 1 1 0 fzo-like conserved region NRBF2 PF08961.10 VBB29594.1 - 0.05 13.2 3.2 0.14 11.7 3.2 1.7 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 VBB29594.1 - 0.1 13.1 6.0 0.33 11.4 6.0 1.9 1 0 0 1 1 1 0 Cell division protein ZapB JIP_LZII PF16471.5 VBB29594.1 - 1.2 9.4 12.5 0.11 12.6 5.1 3.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 VBB29594.1 - 1.5 9.1 5.4 0.41 10.9 1.7 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Senescence PF06911.12 VBB29595.1 - 3.1e-19 70.0 10.8 2.2e-17 64.0 1.1 2.8 2 1 1 3 3 3 2 Senescence-associated protein DUF4246 PF14033.6 VBB29595.1 - 0.0094 15.1 0.6 0.019 14.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) DUF1788 PF08747.11 VBB29595.1 - 0.29 11.2 2.3 0.9 9.6 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1788) Ras PF00071.22 VBB29596.1 - 4.7e-17 62.0 0.0 6.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB29596.1 - 0.034 14.4 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 VBB29596.1 - 0.072 12.6 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain IQCJ-SCHIP1 PF15157.6 VBB29596.1 - 1.5 8.7 7.7 4.3 7.2 7.7 1.7 1 1 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Astacin PF01400.24 VBB29597.1 - 6.6e-67 224.8 0.1 1.9e-66 223.3 0.1 1.9 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CTD_bind PF04818.13 VBB29597.1 - 1.5e-11 44.9 0.1 1.5e-11 44.9 0.1 3.3 4 0 0 4 4 4 1 RNA polymerase II-binding domain. CUB PF00431.20 VBB29597.1 - 5.3e-07 30.0 0.4 2.5e-06 27.8 0.4 2.2 1 0 0 1 1 1 1 CUB domain CTK3 PF12243.8 VBB29597.1 - 0.011 15.7 0.3 0.047 13.7 0.1 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Reprolysin_4 PF13583.6 VBB29597.1 - 0.013 15.2 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fz PF01392.22 VBB29598.1 - 2.5e-28 98.9 6.2 4.1e-28 98.2 6.2 1.3 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 VBB29598.1 - 1.1e-12 47.7 0.2 1.6e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Anillin_N PF16018.5 VBB29600.1 - 0.12 12.9 1.6 0.85 10.3 1.6 2.1 1 1 0 1 1 1 0 Anillin N-terminus Pkinase PF00069.25 VBB29601.1 - 2.5e-25 89.3 0.0 9.2e-25 87.5 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29601.1 - 1.3e-05 24.6 0.0 3.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase CPG4 PF15481.6 VBB29602.1 - 7.5e-15 55.3 4.7 7.5e-15 55.3 4.7 2.0 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 ABC_tran PF00005.27 VBB29606.1 - 2.3e-69 232.2 0.0 4e-34 118.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 VBB29606.1 - 9e-68 228.9 24.8 5.1e-38 131.3 9.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 VBB29606.1 - 3e-17 62.8 4.8 1.6e-06 27.7 0.4 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 VBB29606.1 - 3.3e-10 40.6 0.0 9.4e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 VBB29606.1 - 1.7e-08 34.0 2.2 0.0054 16.4 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 VBB29606.1 - 4.1e-08 33.6 0.2 0.028 14.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 VBB29606.1 - 8.1e-08 31.5 0.4 0.0018 17.1 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 VBB29606.1 - 2.5e-06 26.9 0.0 0.026 13.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.17 VBB29606.1 - 6.7e-06 26.4 0.3 0.016 15.3 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 VBB29606.1 - 2.9e-05 24.7 0.1 0.37 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 VBB29606.1 - 0.00013 21.8 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 VBB29606.1 - 0.00013 21.9 0.0 0.87 9.5 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_5 PF07728.14 VBB29606.1 - 0.00014 21.9 0.0 0.69 9.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 VBB29606.1 - 0.00015 21.7 1.8 0.1 12.4 0.1 3.2 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 VBB29606.1 - 0.00021 20.9 0.1 0.24 10.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 VBB29606.1 - 0.00025 20.8 3.9 0.32 10.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain Cytidylate_kin PF02224.18 VBB29606.1 - 0.00051 19.8 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase AAA_18 PF13238.6 VBB29606.1 - 0.00062 20.3 0.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 VBB29606.1 - 0.0011 18.8 0.6 2.1 8.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain PRK PF00485.18 VBB29606.1 - 0.0013 18.5 0.3 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 VBB29606.1 - 0.0018 17.5 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_25 PF13481.6 VBB29606.1 - 0.0018 17.9 0.2 4.8 6.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 VBB29606.1 - 0.0024 17.6 0.0 0.92 9.2 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein TniB PF05621.11 VBB29606.1 - 0.0033 16.8 0.1 0.56 9.6 0.0 3.3 4 0 0 4 4 3 1 Bacterial TniB protein NB-ARC PF00931.22 VBB29606.1 - 0.0038 16.5 0.8 5.9 6.0 0.0 3.4 3 0 0 3 3 3 0 NB-ARC domain DUF3987 PF13148.6 VBB29606.1 - 0.0039 16.2 0.1 0.39 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_33 PF13671.6 VBB29606.1 - 0.0047 17.1 0.0 1.9 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 VBB29606.1 - 0.0049 16.2 0.2 0.39 10.0 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 VBB29606.1 - 0.0055 16.8 0.4 6.5 6.9 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase Sigma54_activat PF00158.26 VBB29606.1 - 0.0099 15.6 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATP_bind_1 PF03029.17 VBB29606.1 - 0.01 15.7 0.2 3 7.6 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 VBB29606.1 - 0.01 16.2 0.4 12 6.4 0.0 3.7 5 0 0 5 5 2 0 RNA helicase AAA_28 PF13521.6 VBB29606.1 - 0.011 15.9 0.1 17 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 VBB29606.1 - 0.013 14.9 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 VBB29606.1 - 0.028 14.6 0.0 7.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 VBB29606.1 - 0.049 12.7 0.0 5.6 5.9 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 VBB29606.1 - 0.067 13.4 4.1 5.1 7.4 0.4 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 VBB29606.1 - 0.33 10.9 2.9 32 4.4 0.1 3.8 4 0 0 4 4 4 0 NTPase Ceramidase PF05875.12 VBB29606.1 - 4.1 6.7 13.7 0.35 10.3 0.4 3.0 2 1 1 3 3 3 0 Ceramidase Ribosomal_L10 PF00466.20 VBB29607.1 - 1.9e-23 82.5 0.3 5.7e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 VBB29607.1 - 5.1e-20 71.3 0.1 1.1e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 VBB29607.1 - 1.5e-17 63.9 8.9 1.5e-17 63.9 8.9 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein TCTP PF00838.17 VBB29608.1 - 6.4e-35 120.9 0.2 7.2e-35 120.8 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF327 PF03885.13 VBB29608.1 - 0.015 15.2 0.4 0.063 13.2 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF327) SapB_1 PF05184.15 VBB29608.1 - 0.066 13.2 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Saposin-like type B, region 1 VHL PF01847.16 VBB29609.1 - 0.018 15.0 0.3 0.049 13.5 0.3 1.8 1 1 0 1 1 1 0 VHL beta domain UCH PF00443.29 VBB29611.1 - 1.1e-49 169.3 0.1 1.8e-49 168.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 VBB29611.1 - 3.5e-10 39.8 12.9 3.5e-10 39.8 12.9 3.3 3 0 0 3 3 3 1 MYND finger Peptidase_C98 PF15499.6 VBB29611.1 - 0.00013 21.5 0.4 0.16 11.4 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCH_1 PF13423.6 VBB29611.1 - 0.00016 21.4 4.9 0.82 9.2 0.0 3.6 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 VBB29611.1 - 0.0004 20.2 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-C6H2 PF15801.5 VBB29611.1 - 0.31 11.4 15.1 3.1 8.2 0.1 3.2 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding MG4 PF17789.1 VBB29612.1 - 0.16 12.1 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Macroglobulin domain MG4 DNA_ligase_A_M PF01068.21 VBB29613.1 - 1e-58 198.4 1.1 1.5e-58 197.8 0.1 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 VBB29613.1 - 2.5e-31 109.3 1.2 8.4e-31 107.6 0.7 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 VBB29613.1 - 4.6e-19 68.8 0.0 1.6e-18 67.1 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-PARP PF00645.18 VBB29613.1 - 2.1e-14 54.1 0.1 9.8e-14 52.0 0.1 2.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 VBB29613.1 - 2.4e-10 40.2 3.2 4.9e-10 39.2 3.2 1.6 1 0 0 1 1 1 1 PBZ domain RNA_ligase PF09414.10 VBB29613.1 - 4.9e-07 30.2 0.1 1.2e-06 28.9 0.1 1.7 1 0 0 1 1 1 1 RNA ligase Flavoprotein PF02441.19 VBB29614.1 - 0.001 18.9 0.0 1.2 8.9 0.1 2.3 1 1 1 2 2 2 2 Flavoprotein KRTDAP PF15200.6 VBB29614.1 - 0.06 13.1 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Baculo_LEF-10 PF07206.11 VBB29615.1 - 0.2 11.8 0.4 13 6.0 0.2 2.4 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) Methyltransf_31 PF13847.6 VBB29616.1 - 0.015 15.1 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribonuc_red_sm PF00268.21 VBB29617.1 - 3.5e-108 361.3 4.8 5.1e-108 360.8 4.8 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribosomal_L9_N PF01281.19 VBB29618.1 - 0.2 11.3 0.2 0.2 11.3 0.2 1.9 3 0 0 3 3 3 0 Ribosomal protein L9, N-terminal domain TPR_1 PF00515.28 VBB29619.1 - 0.49 10.3 8.7 22 5.1 0.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UCH PF00443.29 VBB29622.1 - 4e-59 200.2 1.1 7.2e-59 199.4 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DnaJ_C PF01556.18 VBB29622.1 - 2.6e-34 118.5 0.3 5.5e-34 117.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 VBB29622.1 - 2e-25 88.7 2.1 4.7e-25 87.5 2.1 1.7 1 0 0 1 1 1 1 DnaJ domain UCH_1 PF13423.6 VBB29622.1 - 8.8e-19 68.2 7.9 8.8e-19 68.2 7.9 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 VBB29622.1 - 7e-08 32.7 12.8 7e-08 32.7 12.8 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 VBB29622.1 - 0.091 12.2 16.2 0.15 11.5 4.0 3.8 3 1 1 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DSPc PF00782.20 VBB29623.1 - 1.5e-41 141.3 0.0 3.2e-41 140.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB29623.1 - 0.061 13.4 0.2 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate SLC12 PF03522.15 VBB29624.1 - 0.019 14.0 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MoCF_biosynth PF00994.24 VBB29625.1 - 3.6e-27 94.8 0.0 4.6e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain HEPN-like_int PF18867.1 VBB29625.1 - 0.074 12.9 0.1 3.9 7.3 0.1 2.1 2 0 0 2 2 2 0 HEPN-like integron domain TBCA PF02970.16 VBB29627.1 - 8.9e-27 93.3 3.4 1.4e-26 92.7 3.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A Med2 PF11214.8 VBB29627.1 - 0.026 14.6 2.7 0.034 14.3 0.3 1.9 1 1 1 2 2 2 0 Mediator complex subunit 2 Herpes_U30 PF04523.13 VBB29627.1 - 0.037 11.9 0.5 0.043 11.7 0.5 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 IKBKB_SDD PF18397.1 VBB29627.1 - 0.067 12.5 3.1 0.082 12.2 3.1 1.0 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Syntaxin-18_N PF10496.9 VBB29627.1 - 0.096 12.9 0.5 0.19 12.0 0.4 1.6 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Vps39_1 PF10366.9 VBB29628.1 - 5e-29 100.7 1.5 5e-29 100.7 1.5 3.2 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 VBB29628.1 - 9.6e-20 71.3 0.0 1.3e-18 67.6 0.0 2.7 3 0 0 3 3 3 1 CNH domain Vps39_2 PF10367.9 VBB29628.1 - 9.6e-11 42.1 0.2 4.2e-10 40.0 0.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 VBB29628.1 - 5.5e-10 39.3 12.6 7e-06 26.0 0.7 4.4 4 1 0 4 4 4 2 Region in Clathrin and VPS D123 PF07065.14 VBB29628.1 - 0.13 11.4 0.4 9.8 5.2 0.3 2.4 2 0 0 2 2 2 0 D123 TFIIA_gamma_C PF02751.14 VBB29629.1 - 9.6e-18 64.1 3.0 9.6e-18 64.1 3.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 VBB29629.1 - 5.8e-16 58.2 0.0 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain WD40_like PF17005.5 VBB29629.1 - 4.4e-11 42.7 1.3 1.2e-05 24.8 0.0 3.5 2 1 2 4 4 4 3 WD40-like domain ANAPC4_WD40 PF12894.7 VBB29629.1 - 2.6e-09 37.2 0.3 0.062 13.6 0.1 4.6 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB29629.1 - 3e-06 27.8 14.5 0.085 13.8 0.1 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Utp8 PF10395.9 VBB29629.1 - 0.052 12.0 0.0 0.2 10.1 0.0 1.7 1 1 1 2 2 2 0 Utp8 family EPL1 PF10513.9 VBB29631.1 - 1.5e-09 38.5 2.2 1.7e-08 35.0 0.0 3.0 3 0 0 3 3 3 1 Enhancer of polycomb-like Med3 PF11593.8 VBB29631.1 - 9.3 5.3 8.3 17 4.5 8.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Astacin PF01400.24 VBB29632.1 - 6.4e-67 224.9 0.0 1.3e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 VBB29632.1 - 6.6e-14 52.2 0.1 1.4e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 VBB29632.1 - 0.00011 22.4 6.3 0.00041 20.5 6.3 2.0 1 0 0 1 1 1 1 Thrombospondin type 1 domain Peptidase_M10 PF00413.24 VBB29632.1 - 0.00064 19.6 0.2 0.84 9.5 0.0 2.7 2 1 0 2 2 2 2 Matrixin DUF3439 PF11921.8 VBB29632.1 - 1.2 9.2 8.6 2.4 8.2 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EGF_2 PF07974.13 VBB29632.1 - 4.7 7.7 22.8 0.038 14.4 12.1 2.8 2 0 0 2 2 2 0 EGF-like domain Reprolysin_4 PF13583.6 VBB29632.1 - 8.3 6.0 8.5 2.7 7.6 0.1 3.5 3 1 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like BCL_N PF04714.13 VBB29633.1 - 5.9e-25 87.1 9.5 1.1e-24 86.2 9.5 1.5 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Stealth_CR2 PF11380.8 VBB29633.1 - 0.087 13.0 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 Lactamase_B_6 PF16661.5 VBB29633.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Peptidase_M10 PF00413.24 VBB29634.1 - 1.2e-45 155.2 0.0 2.8e-45 154.0 0.0 1.6 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 VBB29634.1 - 5.3e-10 39.1 4.2 0.0018 18.2 1.4 3.8 3 0 0 3 3 3 2 Hemopexin PG_binding_1 PF01471.18 VBB29634.1 - 1.7e-06 28.2 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Metallopep PF12044.8 VBB29634.1 - 0.0022 16.7 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family DUF4953 PF16313.5 VBB29634.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 VBB29634.1 - 0.038 12.9 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 VBB29634.1 - 0.039 14.5 0.3 0.085 13.4 0.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 VBB29634.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 adh_short PF00106.25 VBB29635.1 - 3.2e-53 180.1 0.5 5.3e-53 179.4 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 VBB29635.1 - 1.5e-40 139.0 0.0 1e-39 136.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 VBB29635.1 - 2.2e-38 132.1 0.1 3.8e-38 131.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 VBB29635.1 - 6.3e-17 61.5 0.6 1.2e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 VBB29635.1 - 5.1e-16 58.9 0.1 1.9e-11 43.9 0.0 3.1 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 VBB29635.1 - 9.6e-14 51.2 0.8 1.3e-06 27.8 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.10 VBB29635.1 - 1.6e-11 44.4 0.0 3.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 VBB29635.1 - 9.3e-10 38.1 0.0 4.1e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 VBB29635.1 - 0.00045 19.7 0.0 0.0046 16.4 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 VBB29635.1 - 0.0075 16.2 0.0 5 7.0 0.0 2.6 2 1 0 2 2 2 2 NAD(P)H-binding PSP94 PF05825.11 VBB29635.1 - 0.027 15.0 0.9 0.065 13.8 0.2 2.0 2 0 0 2 2 2 0 Beta-microseminoprotein (PSP-94) Raptor_N PF14538.6 VBB29636.1 - 2.2e-17 63.4 0.0 2.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Tubulin PF00091.25 VBB29637.1 - 5.5e-65 219.3 0.0 7.3e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB29637.1 - 6.4e-49 165.3 0.0 1e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 VBB29637.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Cyclin_N PF00134.23 VBB29639.1 - 5.7e-05 22.9 1.6 0.0017 18.1 1.6 2.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain IHHNV_capsid PF16530.5 VBB29639.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Cyclin_C PF02984.19 VBB29640.1 - 3.7e-24 85.1 0.3 9.4e-24 83.8 0.2 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 VBB29640.1 - 1.2e-21 76.8 0.4 1.6e-20 73.2 0.0 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Collagen PF01391.18 VBB29641.1 - 2.8e-18 65.4 65.6 4.4e-10 39.2 25.8 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CT_C_D PF02682.16 VBB29642.1 - 0.15 11.8 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF1794 PF08768.11 VBB29644.1 - 3.1e-23 82.4 0.0 5.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) XPG_I PF00867.18 VBB29644.1 - 6e-18 65.0 1.4 9.5e-18 64.4 0.2 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 VBB29644.1 - 3.9e-16 59.4 0.0 8.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain ShK PF01549.24 VBB29644.1 - 0.0019 18.7 8.0 0.091 13.3 7.9 3.0 2 0 0 2 2 2 1 ShK domain-like TPR_2 PF07719.17 VBB29644.1 - 0.054 13.6 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat XPG_I_2 PF12813.7 VBB29644.1 - 0.084 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing BTD PF09270.10 VBB29646.1 - 5e-58 195.7 0.2 2.7e-57 193.3 0.0 2.2 2 1 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 VBB29646.1 - 1.4e-49 168.6 0.2 2.4e-49 167.8 0.2 1.4 1 0 0 1 1 1 1 LAG1, DNA binding Nucleolin_bd PF16725.5 VBB29646.1 - 0.56 9.9 2.9 1.2 8.8 2.9 1.5 1 0 0 1 1 1 0 Nucleolin binding domain DnaJ PF00226.31 VBB29648.1 - 9e-16 57.8 1.2 1.3e-15 57.2 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain Bin3 PF06859.12 VBB29649.1 - 0.95 10.1 4.7 3.5 8.3 1.3 3.3 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Hormone_recep PF00104.30 VBB29653.1 - 4e-37 127.8 1.3 5.5e-37 127.4 1.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 VBB29653.1 - 1.4e-30 105.5 14.7 2.6e-30 104.7 14.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) THDPS_N PF14790.6 VBB29653.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Integrase_H2C2 PF17921.1 VBB29654.1 - 3.8e-12 46.1 0.7 7.6e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB29654.1 - 0.017 15.3 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger DXP_synthase_N PF13292.6 VBB29654.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase zf-C2H2 PF00096.26 VBB29655.1 - 8e-13 48.1 40.3 0.012 16.0 1.4 7.0 6 0 0 6 6 6 6 Zinc finger, C2H2 type BTB PF00651.31 VBB29655.1 - 7.4e-09 35.8 0.0 2.2e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 VBB29655.1 - 4.1e-05 24.1 57.8 0.01 16.6 2.0 8.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB29655.1 - 9e-05 22.7 41.3 0.094 13.0 1.4 8.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 VBB29655.1 - 0.007 16.1 39.2 0.11 12.3 0.8 6.3 6 0 0 6 6 6 4 zinc-finger C2H2-type zf-met PF12874.7 VBB29655.1 - 0.33 11.4 38.8 0.97 9.9 0.5 7.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 VBB29655.1 - 2.5 7.8 30.5 0.12 12.0 0.1 6.0 6 0 0 6 6 6 0 MYST family zinc finger domain GTP_EFTU PF00009.27 VBB29656.1 - 3.1e-43 147.6 0.0 6.6e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 VBB29656.1 - 4.4e-29 101.0 1.2 1.8e-28 99.1 0.4 2.6 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 VBB29656.1 - 1.5e-07 31.6 0.6 3.5e-07 30.5 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 VBB29656.1 - 0.012 15.7 0.0 0.18 11.9 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase PAM2 PF07145.15 VBB29656.1 - 0.16 11.7 5.1 0.25 11.1 0.5 3.0 2 1 1 3 3 3 0 Ataxin-2 C-terminal region Ribosomal_L1 PF00687.21 VBB29657.1 - 4.1e-10 39.7 0.9 1.2e-09 38.2 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein L1p/L10e family Chlor_dismutase PF06778.12 VBB29657.1 - 0.044 13.3 0.5 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Chlorite dismutase Ras PF00071.22 VBB29659.1 - 3.2e-57 192.7 0.1 4.9e-57 192.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB29659.1 - 3.3e-21 75.7 0.0 5.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB29659.1 - 2.2e-09 37.0 0.0 2.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB29659.1 - 3.9e-05 23.6 0.0 0.097 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 VBB29659.1 - 0.00013 21.5 0.4 0.001 18.7 0.2 2.4 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB29659.1 - 0.00071 19.6 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 VBB29659.1 - 0.02 14.1 0.0 0.94 8.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit PRP38 PF03371.15 VBB29659.1 - 0.086 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 PRP38 family NOA36 PF06524.12 VBB29660.1 - 2.6 7.3 11.2 2.9 7.1 11.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 VBB29660.1 - 6.7 6.4 9.7 7.9 6.1 9.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Arylesterase PF01731.20 VBB29661.1 - 0.037 14.2 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Acetyltransf_18 PF18014.1 VBB29662.1 - 2e-08 34.1 0.2 2.7e-07 30.5 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Prenylcys_lyase PF07156.14 VBB29664.1 - 1.2e-63 215.4 6.4 5.1e-63 213.4 6.4 1.9 1 1 0 1 1 1 1 Prenylcysteine lyase TPR_1 PF00515.28 VBB29664.1 - 3.1e-23 80.6 15.7 6.1e-06 25.8 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29664.1 - 1.6e-21 74.6 14.5 0.0021 18.0 0.1 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 VBB29664.1 - 2.4e-19 67.9 8.0 0.0035 17.4 0.0 7.5 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29664.1 - 6e-14 51.3 15.0 0.0052 17.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29664.1 - 2.8e-12 46.7 6.4 0.0054 17.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29664.1 - 1.3e-11 44.3 8.1 0.023 15.5 0.0 6.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29664.1 - 1.7e-11 44.5 10.6 0.0018 18.7 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat NAD_binding_8 PF13450.6 VBB29664.1 - 3.4e-08 33.6 0.1 8.4e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPR_11 PF13414.6 VBB29664.1 - 5.6e-07 29.1 12.1 0.69 9.6 0.0 6.4 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 VBB29664.1 - 7.2e-07 29.8 10.4 0.29 11.8 0.3 6.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB29664.1 - 1.6e-06 27.7 5.4 0.59 10.3 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB29664.1 - 1.1e-05 25.7 12.7 0.53 11.0 0.2 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB29664.1 - 4.4e-05 22.8 1.5 0.094 11.9 0.7 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29664.1 - 0.00025 21.2 7.4 0.39 11.0 0.1 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NAD_binding_9 PF13454.6 VBB29664.1 - 0.00026 21.0 0.1 0.16 11.9 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 VBB29664.1 - 0.0014 17.9 0.2 0.071 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPR_9 PF13371.6 VBB29664.1 - 0.0016 18.6 8.1 0.52 10.5 0.3 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB29664.1 - 0.0072 16.2 11.0 0.23 11.4 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DAO PF01266.24 VBB29664.1 - 0.011 15.3 0.3 0.023 14.3 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPR_20 PF14561.6 VBB29664.1 - 0.025 14.9 3.8 5.2 7.5 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 VBB29664.1 - 0.042 13.9 0.0 0.41 10.7 0.0 2.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 VBB29664.1 - 0.044 13.8 2.7 2.3 8.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 VBB29664.1 - 0.14 12.8 6.8 18 6.3 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 VBB29664.1 - 0.23 11.1 1.6 0.83 9.3 0.1 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) MIT PF04212.18 VBB29664.1 - 0.25 11.5 1.4 2.7 8.1 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain RHH_6 PF16762.5 VBB29665.1 - 2.4 8.8 9.6 4.3 8.0 1.5 2.4 1 1 1 2 2 2 0 Ribbon-helix-helix domain Innexin PF00876.18 VBB29667.1 - 3.8e-126 421.1 17.0 4.4e-126 420.9 17.0 1.0 1 0 0 1 1 1 1 Innexin Catalase-rel PF06628.12 VBB29667.1 - 0.14 12.4 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive DUF1098 PF06497.11 VBB29668.1 - 0.00073 20.0 0.4 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1098) Mog1 PF04603.12 VBB29668.1 - 0.3 11.4 2.1 0.54 10.6 0.2 2.0 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Ets PF00178.22 VBB29669.1 - 4e-31 107.3 3.0 9.1e-31 106.2 3.0 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 VBB29669.1 - 1.1e-14 54.2 0.1 2.3e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain TGT_C2 PF14810.6 VBB29669.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Amino_oxidase PF01593.24 VBB29670.1 - 4.2e-57 194.4 0.0 4.6e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Guanylate_kin PF00625.21 VBB29671.1 - 1.2e-49 168.4 0.7 1.2e-49 168.4 0.7 2.3 3 0 0 3 3 3 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 VBB29671.1 - 1.5e-17 63.4 5.8 1.5e-17 63.4 5.8 2.3 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 VBB29671.1 - 0.0042 16.7 0.1 0.0085 15.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF4628 PF15429.6 VBB29671.1 - 0.021 14.5 9.7 2.5 7.7 7.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4628) DUF2722 PF10846.8 VBB29671.1 - 0.025 13.6 12.9 0.05 12.5 12.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SH3_2 PF07653.17 VBB29671.1 - 0.059 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain CNDH2_M PF16869.5 VBB29671.1 - 0.23 12.2 7.5 3.3 8.4 8.8 2.3 2 0 0 2 2 2 0 PF16858 Spt20 PF12090.8 VBB29671.1 - 0.59 9.7 21.6 0.29 10.7 19.2 1.7 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.13 VBB29671.1 - 0.73 10.5 13.5 1.7 9.3 13.5 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 VBB29671.1 - 2.1 7.0 6.9 3.2 6.3 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 VBB29671.1 - 4.3 8.3 7.7 0.53 11.3 2.5 2.3 3 0 0 3 3 1 0 Domain of unknown function (DUF4834) FAM184 PF15665.5 VBB29672.1 - 0.0033 17.2 2.3 0.0055 16.5 2.3 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Sec2p PF06428.11 VBB29672.1 - 0.0051 16.7 5.5 0.016 15.1 3.5 2.4 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p zf-ribbon_3 PF13248.6 VBB29672.1 - 0.0067 15.8 0.7 0.03 13.7 0.7 2.2 1 0 0 1 1 1 1 zinc-ribbon domain DUF1640 PF07798.11 VBB29672.1 - 0.012 15.6 2.6 0.026 14.6 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2046 PF09755.9 VBB29672.1 - 0.023 13.9 6.2 0.015 14.5 4.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) TLE_N PF03920.15 VBB29672.1 - 0.034 14.2 2.9 0.06 13.4 2.9 1.3 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain VEK-30 PF12107.8 VBB29672.1 - 1.1 9.2 3.7 2.6 8.1 3.7 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway CENP-F_leu_zip PF10473.9 VBB29672.1 - 2.3 8.3 9.3 0.32 11.0 4.0 2.3 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bcr-Abl_Oligo PF09036.10 VBB29672.1 - 2.5 8.1 8.7 9.9 6.3 1.4 3.3 2 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain OmpH PF03938.14 VBB29672.1 - 2.9 8.2 8.6 7.5 6.9 8.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 VBB29672.1 - 3.7 8.1 7.8 0.91 10.0 4.5 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region LETM1 PF07766.13 VBB29674.1 - 4.3e-98 327.9 6.4 4.3e-98 327.9 6.4 2.0 2 1 0 2 2 2 1 LETM1-like protein SAP PF02037.27 VBB29674.1 - 0.00027 20.6 0.1 0.0041 16.8 0.1 2.9 2 1 0 2 2 2 1 SAP domain DUF1682 PF07946.14 VBB29674.1 - 0.0066 15.7 5.6 0.0066 15.7 5.6 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1682) Syntaxin_2 PF14523.6 VBB29674.1 - 0.035 14.5 1.1 0.035 14.5 1.1 4.2 5 0 0 5 5 5 0 Syntaxin-like protein Vps39_1 PF10366.9 VBB29674.1 - 0.32 11.3 4.3 0.14 12.4 0.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Syntaxin-6_N PF09177.11 VBB29674.1 - 8.7 7.0 20.9 0.96 10.0 0.6 4.8 4 1 0 4 4 4 0 Syntaxin 6, N-terminal RINT1_TIP1 PF04437.13 VBB29675.1 - 4e-64 217.3 12.4 4e-64 217.3 12.4 2.8 2 2 0 2 2 2 1 RINT-1 / TIP-1 family UCH PF00443.29 VBB29675.1 - 0.013 15.0 4.4 0.11 12.0 4.4 2.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF1420 PF07220.11 VBB29675.1 - 0.041 12.5 0.0 0.069 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1420) PACT_coil_coil PF10495.9 VBB29675.1 - 0.34 11.5 3.4 1.4 9.6 3.4 2.1 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Peptidase_M75 PF09375.10 VBB29675.1 - 0.88 9.0 3.9 0.76 9.2 2.2 1.7 2 0 0 2 2 2 0 Imelysin CNDH2_C PF16858.5 VBB29676.1 - 4.7e-54 184.3 3.1 4.7e-54 184.3 3.1 2.3 2 1 1 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 VBB29676.1 - 3.8e-26 91.5 0.2 1e-25 90.1 0.2 1.7 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 VBB29676.1 - 3.4e-07 31.0 1.5 1e-06 29.5 1.5 1.9 1 0 0 1 1 1 1 PF16858 WD40 PF00400.32 VBB29677.1 - 3e-09 37.3 16.3 0.1 13.5 1.4 7.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29677.1 - 3.6e-06 27.2 0.0 0.12 12.7 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 VBB29677.1 - 0.00046 19.6 0.0 0.038 13.2 0.0 2.8 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller Zip PF02535.22 VBB29678.1 - 8.8e-50 169.8 22.7 3.8e-49 167.7 22.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Methyltransf_PK PF05891.12 VBB29679.1 - 1e-81 273.7 0.1 1.2e-81 273.5 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 VBB29679.1 - 3.7e-09 37.2 0.0 1.2e-08 35.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB29679.1 - 1.6e-08 35.1 0.0 2.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB29679.1 - 3.3e-08 34.2 0.0 6.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB29679.1 - 3.4e-07 30.3 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 VBB29679.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 VBB29679.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 VBB29679.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 VBB29679.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 VBB29679.1 - 0.045 13.3 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 VBB29679.1 - 0.064 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 VBB29679.1 - 0.086 12.2 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ras PF00071.22 VBB29680.1 - 3.3e-15 56.1 0.0 1.1e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 VBB29680.1 - 6e-13 49.1 0.2 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB29680.1 - 0.0008 18.9 0.0 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF1132 PF06575.12 VBB29680.1 - 0.016 15.6 0.3 0.026 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) DLIC PF05783.11 VBB29680.1 - 0.054 12.3 0.1 0.077 11.8 0.1 1.5 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) WD40 PF00400.32 VBB29681.1 - 1.1e-18 67.3 5.9 7.3e-05 23.5 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 VBB29681.1 - 8e-18 64.5 0.2 9.3e-16 57.9 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 VBB29681.1 - 2.5e-06 27.5 0.2 2.4e-05 24.3 0.1 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 VBB29681.1 - 4.2e-06 27.0 2.3 0.013 15.8 0.4 3.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Fe_hyd_lg_C PF02906.14 VBB29682.1 - 2.1e-60 204.4 0.1 4.8e-60 203.2 0.0 1.6 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Sedlin_N PF04628.13 VBB29682.1 - 6e-07 29.6 0.2 1.3e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DpaA_N PF16924.5 VBB29682.1 - 0.092 12.8 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain PHF5 PF03660.14 VBB29683.1 - 2.9e-50 168.8 13.5 3.2e-50 168.7 13.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 VBB29683.1 - 0.091 10.6 7.7 0.094 10.6 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GCP_N_terminal PF17681.1 VBB29684.1 - 1.8e-23 83.6 4.3 5.5e-22 78.8 4.3 2.4 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 VBB29684.1 - 1.2e-21 77.5 6.9 1.2e-21 77.5 6.9 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal ANTH PF07651.16 VBB29685.1 - 1.1e-52 178.8 1.9 4.1e-27 94.9 0.1 2.9 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.20 VBB29685.1 - 4.7e-11 42.8 0.0 9.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 ENTH domain Asparaginase_2 PF01112.18 VBB29686.1 - 3.7e-72 242.9 0.1 4.9e-72 242.5 0.1 1.0 1 0 0 1 1 1 1 Asparaginase AAL_decarboxy PF03306.13 VBB29686.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase GED PF02212.18 VBB29686.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF4773 PF15998.5 VBB29687.1 - 4.3e-28 98.2 3.3 7.1e-28 97.5 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) TMEM144 PF07857.12 VBB29688.1 - 1.8e-48 165.2 8.4 2.5e-48 164.8 8.4 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters ABC2_membrane_5 PF13346.6 VBB29688.1 - 1.2 8.6 9.2 2.1 7.9 9.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ACBP PF00887.19 VBB29689.1 - 7.9e-06 26.0 0.9 1.3e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein MepB PF08877.10 VBB29689.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 MepB protein RNA_pol_Rpb1_4 PF05000.17 VBB29689.1 - 0.042 13.8 0.1 0.18 11.8 0.1 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 4 FERM_M PF00373.18 VBB29689.1 - 0.049 14.0 0.8 0.53 10.7 0.0 2.7 1 1 1 2 2 2 0 FERM central domain DUF1491 PF07372.12 VBB29689.1 - 0.086 13.2 2.0 0.18 12.2 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) BNIP2 PF12496.8 VBB29689.1 - 0.32 11.4 5.6 0.63 10.5 5.4 1.6 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TAP42 PF04177.12 VBB29690.1 - 5.3e-68 229.5 6.0 9.3e-68 228.7 6.0 1.4 1 0 0 1 1 1 1 TAP42-like family RNA_GG_bind PF10258.9 VBB29690.1 - 1.1e-19 70.2 0.0 2.8e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 PHAX RNA-binding domain PEN-2 PF10251.9 VBB29692.1 - 3e-34 117.3 2.7 3.3e-34 117.2 2.7 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase B9-C2 PF07162.11 VBB29693.1 - 2.7e-31 109.1 0.0 4.6e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Piezo_RRas_bdg PF12166.8 VBB29694.1 - 5.4e-100 335.6 1.0 1.2e-99 334.5 1.0 1.7 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 VBB29694.1 - 2.4e-54 184.3 0.4 4.4e-54 183.4 0.4 1.4 1 0 0 1 1 1 1 Piezo DUF4806 PF16064.5 VBB29694.1 - 0.034 14.5 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) RNase_Zc3h12a_2 PF14626.6 VBB29694.1 - 0.037 14.3 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Trs65 PF12735.7 VBB29695.1 - 2.9e-05 23.6 0.0 3e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 2-oxoacid_dh PF00198.23 VBB29697.1 - 3.4e-75 252.5 0.6 4.9e-75 252.0 0.1 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 VBB29697.1 - 2.2e-19 69.1 0.3 5.1e-19 67.9 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 VBB29697.1 - 3.5e-13 49.7 0.2 9.2e-13 48.3 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 VBB29697.1 - 0.00036 20.3 2.4 0.25 11.2 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like PDZ_2 PF13180.6 VBB29698.1 - 9.4e-09 35.5 0.1 0.00021 21.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB29698.1 - 1e-08 34.9 0.0 0.00042 20.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB29698.1 - 2.9e-08 33.9 0.9 0.0017 18.6 0.3 2.9 1 1 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 VBB29698.1 - 5.6e-05 23.0 0.1 0.015 15.3 0.1 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain Pkinase PF00069.25 VBB29699.1 - 8.4e-45 153.2 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29699.1 - 6.3e-21 74.8 0.0 8.8e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29699.1 - 0.0068 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 VBB29699.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Troponin PF00992.20 VBB29700.1 - 3e-44 150.6 9.0 3e-44 150.6 9.0 2.3 2 1 0 2 2 2 1 Troponin TTRAP PF14203.6 VBB29700.1 - 0.067 13.2 2.6 0.072 13.1 0.5 2.2 2 1 0 2 2 2 0 Putative tranposon-transfer assisting protein RTC4 PF14474.6 VBB29700.1 - 0.11 12.7 0.7 0.2 11.8 0.7 1.5 1 0 0 1 1 1 0 RTC4-like domain SH2 PF00017.24 VBB29700.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 SH2 domain E1-E2_ATPase PF00122.20 VBB29701.1 - 3.4e-46 157.0 0.4 1e-45 155.5 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 VBB29701.1 - 2.3e-40 138.2 0.1 2.3e-40 138.2 0.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 VBB29701.1 - 6.3e-22 77.5 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 VBB29701.1 - 1.1e-21 78.1 0.2 1.4e-11 45.1 0.0 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 VBB29701.1 - 1.2e-17 63.3 0.0 2.2e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 VBB29701.1 - 2.6e-06 27.4 3.2 0.00099 18.9 0.6 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB29701.1 - 0.017 15.5 0.5 0.14 12.5 0.1 2.6 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase 7tm_7 PF08395.12 VBB29701.1 - 0.062 12.5 10.3 0.25 10.5 0.9 3.0 3 0 0 3 3 3 0 7tm Chemosensory receptor Phage_holin_3_6 PF07332.11 VBB29701.1 - 5 7.2 7.3 25 5.0 4.9 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Y_phosphatase PF00102.27 VBB29702.1 - 9.4e-50 169.4 0.9 1.6e-49 168.6 0.9 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TMEM144 PF07857.12 VBB29703.1 - 1.6e-48 165.4 12.6 1.8e-48 165.3 12.6 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 VBB29703.1 - 5.2e-11 42.4 6.7 6.8e-11 42.0 6.7 1.1 1 0 0 1 1 1 1 Sugar transport protein PP2C PF00481.21 VBB29704.1 - 1.1e-55 189.1 0.0 1.4e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 VBB29704.1 - 3.3e-06 26.9 0.1 1.5e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C DUF4528 PF15031.6 VBB29704.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) MAM33 PF02330.16 VBB29705.1 - 6.5e-21 75.3 3.3 1.9e-20 73.7 3.3 1.7 1 1 0 1 1 1 1 Mitochondrial glycoprotein Motile_Sperm PF00635.26 VBB29706.1 - 1.2e-20 73.4 0.4 1.5e-19 69.8 0.4 3.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Methyltransf_31 PF13847.6 VBB29707.1 - 1.7e-12 47.4 1.1 3.9e-12 46.2 1.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB29707.1 - 5.4e-06 27.1 0.6 1.8e-05 25.4 0.6 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB29707.1 - 3.9e-05 24.3 0.3 0.0013 19.4 0.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB29707.1 - 6.4e-05 23.5 0.1 0.00061 20.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB29707.1 - 0.0012 18.7 0.1 0.0072 16.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 VBB29707.1 - 0.051 13.6 0.0 0.098 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 VBB29707.1 - 0.12 11.9 0.2 1.1 8.7 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase small domain BCAS2 PF05700.11 VBB29708.1 - 7e-54 182.7 5.6 1.4e-53 181.7 5.6 1.5 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) C2 PF00168.30 VBB29708.1 - 4.1e-52 174.8 0.0 2.8e-27 95.0 0.0 3.5 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 VBB29708.1 - 1.4e-40 138.7 0.0 2.2e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain CLN3 PF02487.17 VBB29710.1 - 5.3e-136 453.8 11.2 6e-136 453.6 11.3 1.0 1 0 0 1 1 1 1 CLN3 protein TPR_2 PF07719.17 VBB29711.1 - 1e-08 34.6 0.9 0.0015 18.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 VBB29711.1 - 2e-08 34.4 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 VBB29711.1 - 1.3e-07 31.1 3.7 0.0023 17.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29711.1 - 2.7e-05 24.6 0.1 0.011 16.4 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 VBB29711.1 - 0.0024 17.5 8.0 0.1 12.3 0.6 3.3 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 VBB29711.1 - 0.015 15.6 1.9 20 5.6 0.0 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 VBB29711.1 - 0.022 14.9 0.1 0.064 13.4 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29711.1 - 0.041 14.4 0.9 0.11 13.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29711.1 - 0.079 13.2 4.2 0.32 11.3 2.8 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Bclx_interact PF08945.10 VBB29711.1 - 0.4 10.5 1.4 12 5.7 0.2 2.3 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain DZF PF07528.14 VBB29712.1 - 9.1e-76 254.7 0.1 9.1e-76 254.7 0.1 2.4 2 0 0 2 2 2 1 DZF domain Nuf2 PF03800.14 VBB29712.1 - 3.2e-19 69.4 0.6 1.4e-18 67.4 0.6 2.1 1 0 0 1 1 1 1 Nuf2 family NTP_transf_2 PF01909.23 VBB29712.1 - 0.17 12.2 0.4 1 9.7 0.0 2.6 2 0 0 2 2 2 0 Nucleotidyltransferase domain COG2 PF06148.11 VBB29712.1 - 2.5 8.2 21.0 3.1 7.9 0.7 4.2 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Usp PF00582.26 VBB29712.1 - 5.6 7.5 7.1 31 5.1 7.1 2.2 1 1 0 1 1 1 0 Universal stress protein family InaF-motif PF15018.6 VBB29713.1 - 1.5e-17 63.1 4.1 2.1e-17 62.7 4.1 1.2 1 0 0 1 1 1 1 TRP-interacting helix ATP-synt_8 PF00895.20 VBB29714.1 - 0.052 14.0 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 ATP synthase protein 8 RNA_binding PF01877.17 VBB29715.1 - 9.5 6.5 16.5 8.9 6.6 12.2 2.8 1 1 1 2 2 2 0 RNA binding HECT PF00632.25 VBB29717.1 - 4.4e-89 299.0 0.1 7.5e-89 298.2 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 VBB29717.1 - 0.0019 17.8 0.3 0.15 12.0 0.1 3.4 3 0 0 3 3 3 1 IQ calmodulin-binding motif ARID PF01388.21 VBB29717.1 - 0.017 15.7 0.2 0.98 10.1 0.0 3.1 3 0 0 3 3 3 0 ARID/BRIGHT DNA binding domain TMIE PF16038.5 VBB29718.1 - 6.4e-23 80.4 0.4 8.6e-23 80.0 0.4 1.2 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 VBB29718.1 - 0.0064 16.8 0.1 0.0064 16.8 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM190 PF15431.6 VBB29718.1 - 0.06 13.5 0.0 0.079 13.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 LapA_dom PF06305.11 VBB29718.1 - 0.088 12.6 1.1 0.15 11.9 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM100 PF16311.5 VBB29718.1 - 0.65 9.6 4.3 0.52 9.9 1.6 1.9 1 1 1 2 2 2 0 Transmembrane protein 100 EphA2_TM PF14575.6 VBB29718.1 - 0.84 10.6 3.1 1.6 9.7 3.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 VBB29718.1 - 2.3 8.2 4.8 5.9 6.9 3.9 1.9 1 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein Peptidase_C13 PF01650.18 VBB29719.1 - 3.2e-43 148.1 0.2 5.5e-43 147.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family LSM PF01423.22 VBB29719.1 - 2e-09 37.0 1.3 2.9e-08 33.3 0.2 2.3 2 0 0 2 2 2 1 LSM domain ArgoMid PF16487.5 VBB29719.1 - 0.0022 18.2 0.0 0.0074 16.5 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Hfq PF17209.3 VBB29719.1 - 0.05 13.3 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Hfq protein DUF382 PF04037.13 VBB29721.1 - 1.3e-57 193.4 0.6 1.3e-57 193.4 0.6 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 VBB29721.1 - 1.2e-19 69.9 2.8 2.6e-19 68.8 2.8 1.6 1 0 0 1 1 1 1 PSP YL1 PF05764.13 VBB29722.1 - 1e-22 81.5 29.1 2.4e-16 60.6 11.8 3.1 2 1 1 3 3 3 2 YL1 nuclear protein YL1_C PF08265.11 VBB29722.1 - 3.3e-12 45.9 0.1 6.3e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain ARD PF03079.14 VBB29722.1 - 0.83 9.8 11.1 0.44 10.7 5.6 2.3 2 0 0 2 2 2 0 ARD/ARD' family DUF3693 PF12472.8 VBB29724.1 - 0.054 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage related protein UQ_con PF00179.26 VBB29725.1 - 2e-15 56.6 0.0 3.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Patched PF02460.18 VBB29728.1 - 2.4e-240 800.0 10.2 3.8e-212 706.7 11.3 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 VBB29728.1 - 6.7e-36 123.4 7.6 6.7e-36 123.4 7.6 3.0 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation DUF1687 PF07955.11 VBB29728.1 - 0.017 15.6 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) DUF725 PF05267.12 VBB29728.1 - 0.24 11.4 2.7 0.46 10.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Na_sulph_symp PF00939.19 VBB29730.1 - 3.1e-53 181.5 10.1 7.3e-53 180.3 10.1 1.5 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 VBB29730.1 - 6.1e-26 91.3 18.4 2.2e-15 56.6 8.8 2.2 2 0 0 2 2 2 2 Citrate transporter EcsB PF05975.12 VBB29730.1 - 6.4 5.5 14.1 0.37 9.6 6.6 2.4 2 1 0 2 2 2 0 Bacterial ABC transporter protein EcsB Patched PF02460.18 VBB29733.1 - 5.4e-63 213.3 27.6 3.3e-35 121.4 2.9 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 VBB29733.1 - 3.1e-34 118.0 5.4 3.1e-34 118.0 5.4 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 VBB29733.1 - 3.8 6.4 22.3 0.0068 15.4 3.0 2.3 2 0 0 2 2 2 0 MMPL family Collagen PF01391.18 VBB29734.1 - 6.8e-13 48.2 140.9 8.8e-10 38.2 26.1 6.6 2 1 1 3 3 3 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB29734.1 - 5.3e-08 32.8 0.3 6.9e-08 32.4 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 VBB29736.1 - 5.8e-61 206.2 0.0 1.6e-60 204.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29736.1 - 5.2e-36 124.3 0.0 8.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 VBB29736.1 - 7.5e-24 83.6 26.5 5.1e-12 45.7 8.0 3.8 3 0 0 3 3 3 3 Hr1 repeat Pkinase_C PF00433.24 VBB29736.1 - 1.1e-08 35.6 2.5 4.9e-08 33.5 2.5 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 VBB29736.1 - 8.7e-06 25.2 0.0 5.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF4200 PF13863.6 VBB29736.1 - 3 8.3 15.5 0.23 11.9 6.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4686 PF15742.5 VBB29736.1 - 3.5 6.7 17.2 0.043 12.9 3.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4686) DUF724 PF05266.14 VBB29736.1 - 4.3 7.1 12.7 2.4 8.0 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ArfGap PF01412.18 VBB29740.1 - 1.8e-32 111.8 3.5 2.4e-32 111.4 0.1 2.6 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.13 VBB29740.1 - 0.21 11.8 2.7 0.41 10.8 1.7 2.0 2 0 0 2 2 2 0 Piccolo Zn-finger GCV_T PF01571.21 VBB29742.1 - 1.3e-16 60.7 0.0 1e-12 48.0 0.0 2.7 2 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain Tam41_Mmp37 PF09139.11 VBB29742.1 - 0.032 13.7 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial GCV_T_C PF08669.11 VBB29742.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Abhydrolase_1 PF00561.20 VBB29743.1 - 5.3e-35 121.3 6.2 3.8e-20 72.6 1.7 3.7 3 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 VBB29743.1 - 2.5e-24 84.6 0.2 6.2e-24 83.4 0.2 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 VBB29743.1 - 9.6e-10 38.1 0.0 0.0016 17.7 0.0 3.8 3 1 0 3 3 3 2 Serine aminopeptidase, S33 VirJ PF06057.11 VBB29743.1 - 0.0053 16.7 0.3 2.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial virulence protein (VirJ) Cutinase PF01083.22 VBB29743.1 - 0.034 14.1 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Cutinase SIT PF15330.6 VBB29743.1 - 0.069 13.6 1.3 8.6 6.8 0.2 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Palm_thioest PF02089.15 VBB29743.1 - 0.14 12.0 1.4 0.33 10.7 0.0 2.2 2 1 0 2 2 2 0 Palmitoyl protein thioesterase Abhydro_lipase PF04083.16 VBB29744.1 - 5.5e-22 77.1 0.1 7e-22 76.8 0.1 1.2 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Cnd3 PF12719.7 VBB29745.1 - 3.3e-49 167.7 1.6 8.1e-49 166.4 1.6 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 VBB29745.1 - 0.051 13.8 5.5 15 6.2 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 VBB29745.1 - 0.12 12.8 6.7 6.2 7.3 0.1 4.2 5 1 0 5 5 5 0 HEAT repeats BTB PF00651.31 VBB29746.1 - 2.2e-08 34.3 0.0 1.5e-06 28.4 0.0 2.5 2 1 0 2 2 2 2 BTB/POZ domain Kelch_1 PF01344.25 VBB29747.1 - 3.1e-65 215.5 17.8 1.6e-12 46.8 0.1 6.8 7 0 0 7 7 7 6 Kelch motif Galactosyl_T PF01762.21 VBB29747.1 - 2.3e-34 118.9 1.8 3.8e-34 118.2 1.8 1.3 1 0 0 1 1 1 1 Galactosyltransferase Kelch_4 PF13418.6 VBB29747.1 - 3.5e-29 100.6 4.1 1.3e-05 25.1 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 VBB29747.1 - 5.4e-29 99.5 7.2 0.00033 20.8 0.0 6.6 3 2 3 6 6 6 6 Kelch motif Kelch_3 PF13415.6 VBB29747.1 - 1.2e-22 79.7 1.7 0.00018 21.7 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 VBB29747.1 - 5e-14 51.6 13.3 0.00043 20.1 0.1 6.4 6 0 0 6 6 6 3 Kelch motif BTB PF00651.31 VBB29747.1 - 1e-09 38.6 0.9 8.8e-09 35.6 0.9 2.3 1 1 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 VBB29747.1 - 2e-06 27.7 6.8 0.075 13.0 0.0 5.2 5 0 0 5 5 5 2 Kelch motif BACK PF07707.15 VBB29747.1 - 0.00083 19.4 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Fringe PF02434.16 VBB29747.1 - 0.00098 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Fringe-like DUF5082 PF16888.5 VBB29748.1 - 0.0079 16.5 1.6 2.7 8.3 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) KOG2701 PF09762.9 VBB29748.1 - 0.02 15.2 0.8 0.035 14.3 0.3 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) Pox_EPC_I2-L1 PF12575.8 VBB29748.1 - 0.24 11.7 6.8 3.7 7.8 0.1 3.2 4 0 0 4 4 4 0 Poxvirus entry protein complex L1 and I2 FTCD_C PF04961.12 VBB29748.1 - 0.25 11.1 2.6 3.7 7.3 0.2 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Thioredoxin PF00085.20 VBB29749.1 - 1.2e-16 60.5 0.1 1.3e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 VBB29749.1 - 0.0018 18.7 0.1 0.037 14.5 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 VBB29749.1 - 0.021 14.2 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 VBB29750.1 - 2.2e-28 98.2 0.2 2.7e-27 94.8 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 VBB29750.1 - 1.9e-07 31.2 0.0 4e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 VBB29750.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 VBB29750.1 - 0.067 13.6 0.2 3.4 8.1 0.2 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain HyaE PF07449.11 VBB29750.1 - 0.072 13.1 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DDE_Tnp_IS1595 PF12762.7 VBB29751.1 - 9.5e-18 64.7 0.1 1.4e-15 57.6 0.0 2.2 1 1 1 2 2 2 2 ISXO2-like transposase domain DIM1 PF02966.16 VBB29752.1 - 4.2e-66 220.7 0.0 4.7e-66 220.6 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 VBB29752.1 - 2.1e-06 27.6 0.0 2.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 VBB29752.1 - 0.0027 18.0 0.2 0.0039 17.5 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 VBB29752.1 - 0.015 15.4 0.0 0.027 14.7 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredox_DsbH PF03190.15 VBB29752.1 - 0.053 13.5 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Med21 PF11221.8 VBB29753.1 - 6.4e-17 62.2 4.7 1.5e-08 35.0 0.0 2.0 1 1 1 2 2 2 2 Subunit 21 of Mediator complex Glycolytic PF00274.19 VBB29754.1 - 2e-177 589.2 0.0 2.2e-177 589.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Med1 PF10744.9 VBB29756.1 - 0.0017 17.4 0.1 0.0043 16.1 0.1 1.5 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 UBX PF00789.20 VBB29757.1 - 1.9e-12 47.2 0.0 4.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain PDE8 PF08629.10 VBB29757.1 - 0.43 10.6 1.6 1.3 9.1 0.6 2.2 2 0 0 2 2 2 0 PDE8 phosphodiesterase DUF4139 PF13598.6 VBB29757.1 - 0.49 10.1 4.3 0.39 10.4 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4139) Glyco_hyd_65N_2 PF14498.6 VBB29757.1 - 1.2 8.9 5.8 3.5 7.4 1.2 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain E1-E2_ATPase PF00122.20 VBB29758.1 - 2.5e-20 72.8 0.0 1e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 VBB29758.1 - 2.3e-18 67.2 0.0 7.2e-10 39.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 VBB29758.1 - 0.00016 21.7 0.0 0.00045 20.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 VBB29758.1 - 0.034 13.9 0.1 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase 2-Hacid_dh_C PF02826.19 VBB29758.1 - 0.13 11.6 0.1 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SET PF00856.28 VBB29759.1 - 1e-07 32.5 0.0 1.7e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Zwilch PF09817.9 VBB29760.1 - 0.032 12.7 1.1 0.048 12.1 1.1 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch DUF733 PF05306.11 VBB29760.1 - 0.05 13.9 0.9 0.097 13.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF733) AATF-Che1 PF13339.6 VBB29760.1 - 0.21 12.3 1.2 0.36 11.5 1.2 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor PurA PF04845.13 VBB29761.1 - 4e-84 281.4 0.1 4.6e-84 281.1 0.1 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 VBB29761.1 - 0.00016 21.8 2.1 0.22 11.7 0.0 3.5 3 1 0 4 4 4 2 Protein of unknown function (DUF3276) DUF3467 PF11950.8 VBB29761.1 - 0.023 14.9 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) zf-RING_2 PF13639.6 VBB29763.1 - 6.4e-10 39.2 9.7 6.4e-10 39.2 9.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB29763.1 - 6.5e-09 35.5 8.2 1.8e-08 34.1 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB29763.1 - 1.4e-08 34.8 6.9 1.4e-08 34.8 6.9 2.8 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB29763.1 - 1.7e-06 27.8 7.4 1.7e-06 27.8 7.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB29763.1 - 6.3e-06 26.1 1.7 6.3e-06 26.1 1.7 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 VBB29763.1 - 1.4e-05 24.7 7.2 2e-05 24.2 4.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 VBB29763.1 - 6.1e-05 23.0 8.5 0.0002 21.3 3.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 VBB29763.1 - 7.3e-05 22.5 7.9 7.3e-05 22.5 7.9 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB29763.1 - 0.00014 21.7 8.4 0.00014 21.7 8.4 2.3 2 1 1 3 3 3 1 zinc-RING finger domain Fib_alpha PF08702.10 VBB29763.1 - 0.00069 19.8 13.5 0.056 13.6 1.2 2.2 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Zn_ribbon_17 PF17120.5 VBB29763.1 - 0.0064 16.1 7.1 0.0064 16.1 7.1 2.5 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 VBB29763.1 - 0.011 15.8 6.2 0.011 15.8 6.2 2.2 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 VBB29763.1 - 0.013 15.4 5.2 0.013 15.4 5.2 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 VBB29763.1 - 0.06 13.2 1.6 0.06 13.2 1.6 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit SlyX PF04102.12 VBB29763.1 - 0.06 14.0 2.0 0.06 14.0 2.0 2.9 3 1 1 4 4 4 0 SlyX FANCL_C PF11793.8 VBB29763.1 - 0.27 11.4 11.3 0.37 11.0 7.3 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain DUF4795 PF16043.5 VBB29763.1 - 0.96 9.0 13.9 0.12 11.9 7.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) zf-RING_4 PF14570.6 VBB29763.1 - 2.4 8.0 8.9 2.7 7.8 5.9 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 VBB29763.1 - 2.5 8.3 15.9 3.1 8.0 5.1 3.0 2 2 0 2 2 2 0 Zinc-ribbon like family zf-RING-like PF08746.11 VBB29763.1 - 4.6 7.6 16.0 0.083 13.2 8.8 1.9 2 0 0 2 2 1 0 RING-like domain 7tm_1 PF00001.21 VBB29764.1 - 0.0015 17.9 14.5 0.011 15.1 14.2 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FA_hydroxylase PF04116.13 VBB29764.1 - 0.035 14.4 1.7 0.061 13.7 1.0 1.8 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily DUF373 PF04123.13 VBB29764.1 - 0.22 10.9 1.7 5.2 6.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Glyco_transf_43 PF03360.16 VBB29765.1 - 1.5e-51 175.2 0.1 1.7e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 ANAPC4_WD40 PF12894.7 VBB29766.1 - 1.7e-09 37.9 0.1 0.091 13.1 0.1 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB29766.1 - 3.6e-08 34.0 8.5 0.006 17.4 3.6 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 VBB29766.1 - 1.4e-06 28.3 0.0 0.00088 19.2 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 VBB29766.1 - 0.012 14.2 0.0 2.4 6.6 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 VBB29766.1 - 0.049 14.1 0.1 51 4.5 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain VID27 PF08553.10 VBB29766.1 - 0.1 11.7 0.1 4.3 6.3 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Mob1_phocein PF03637.17 VBB29767.1 - 1.8e-49 168.0 1.8 5.1e-38 130.7 0.0 2.6 1 1 1 2 2 2 2 Mob1/phocein family Metallophos PF00149.28 VBB29768.1 - 5.1e-35 121.8 0.7 9.2e-35 121.0 0.5 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF722 PF05263.11 VBB29768.1 - 0.0033 17.7 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF722) STPPase_N PF16891.5 VBB29768.1 - 0.0038 17.6 0.2 0.011 16.2 0.2 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Rav1p_C PF12234.8 VBB29769.1 - 4.3e-60 203.8 15.4 1.2e-50 172.6 3.7 4.6 4 1 0 4 4 4 4 RAVE protein 1 C terminal WD40 PF00400.32 VBB29769.1 - 0.00052 20.8 4.6 0.17 12.8 0.6 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40 PF00400.32 VBB29770.1 - 7.9e-11 42.3 5.2 0.0039 18.0 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Rav1p_C PF12234.8 VBB29770.1 - 4.6e-05 22.0 0.1 0.00013 20.6 0.1 1.9 2 0 0 2 2 2 1 RAVE protein 1 C terminal Orf78 PF06024.12 VBB29771.1 - 0.0016 18.7 6.1 0.47 10.8 0.3 2.4 2 0 0 2 2 2 2 Orf78 (ac78) DUF973 PF06157.11 VBB29771.1 - 4.1 6.4 14.4 9.7 5.1 14.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF973) FtsJ PF01728.19 VBB29772.1 - 3.2e-19 69.7 0.0 8.4e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 VBB29772.1 - 0.0038 15.4 0.1 0.0056 14.8 0.1 1.2 1 0 0 1 1 1 1 Virus-capping methyltransferase tRNA-synt_1 PF00133.22 VBB29773.1 - 2.1e-192 640.6 0.1 3.8e-191 636.4 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 VBB29773.1 - 8.8e-39 132.9 0.0 2.5e-38 131.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Chromo PF00385.24 VBB29773.1 - 1.4e-14 53.7 3.3 5.1e-14 51.9 3.3 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain tRNA-synt_1g PF09334.11 VBB29773.1 - 7.1e-13 48.1 0.2 1.1e-05 24.4 0.0 4.0 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 VBB29773.1 - 1.9e-08 34.1 0.0 1.9e-08 34.1 0.0 3.7 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 VBB29773.1 - 0.0024 17.3 0.0 0.11 11.8 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 VBB29773.1 - 0.005 17.1 0.7 0.005 17.1 0.7 3.1 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Ribosomal_L29 PF00831.23 VBB29774.1 - 1.4e-18 66.6 2.1 1.4e-18 66.6 2.1 2.5 2 1 0 2 2 2 1 Ribosomal L29 protein SNCAIP_SNCA_bd PF16700.5 VBB29774.1 - 0.046 13.5 0.4 0.14 11.9 0.4 1.8 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain NPV_P10 PF05531.12 VBB29774.1 - 0.19 12.2 1.8 0.7 10.4 1.1 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 VBB29774.1 - 0.4 11.1 8.0 0.068 13.6 2.6 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Calponin PF00402.18 VBB29775.1 - 1.3e-41 139.9 28.2 4e-11 42.3 0.8 6.4 6 0 0 6 6 6 6 Calponin family repeat SEA PF01390.20 VBB29776.1 - 1.2e-12 47.8 0.0 7.5e-12 45.3 0.0 2.5 1 0 0 1 1 1 1 SEA domain MLANA PF14991.6 VBB29776.1 - 0.22 11.8 1.1 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein melan-A Pkinase PF00069.25 VBB29777.1 - 1.9e-41 142.2 0.0 5e-39 134.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29777.1 - 5.7e-26 91.4 0.0 1.1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29777.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 VBB29778.1 - 1.2e-17 64.0 24.4 1.2e-17 64.0 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Annexin PF00191.20 VBB29779.1 - 8.2e-11 41.8 1.0 3.6e-05 23.8 0.0 3.2 2 1 1 3 3 3 2 Annexin LIM PF00412.22 VBB29780.1 - 1.7e-33 114.6 36.3 1.6e-12 47.5 7.3 3.6 3 0 0 3 3 3 3 LIM domain DEAD PF00270.29 VBB29781.1 - 1.7e-52 177.7 0.0 4.2e-52 176.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB29781.1 - 7.6e-26 90.6 0.1 9.5e-25 87.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 VBB29781.1 - 1.3e-23 83.3 0.1 2.2e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Pkinase PF00069.25 VBB29782.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29782.1 - 3.2e-39 134.8 0.0 6.4e-39 133.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29782.1 - 1e-05 25.0 0.0 0.0018 17.6 0.0 3.0 2 1 0 2 2 2 1 Kinase-like PB1 PF00564.24 VBB29782.1 - 1.1e-05 25.3 0.3 2e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 VBB29782.1 - 0.0018 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB29782.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 VBB29782.1 - 0.15 11.4 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_A17 PF05380.13 VBB29784.1 - 3.8e-08 33.5 0.0 1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Pao retrotransposon peptidase dsrm PF00035.26 VBB29785.1 - 1.4e-07 32.1 0.1 3.5e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 VBB29785.1 - 7.5e-06 26.0 0.2 6.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain HisG_C PF08029.11 VBB29785.1 - 0.091 12.9 0.2 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 HisG, C-terminal domain CP12 PF02672.15 VBB29785.1 - 0.11 13.3 3.5 0.47 11.2 3.5 2.2 1 0 0 1 1 1 0 CP12 domain DUF349 PF03993.12 VBB29785.1 - 0.19 12.0 5.2 0.79 10.1 5.2 2.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Pyridoxal_deC PF00282.19 VBB29786.1 - 5.1e-146 486.2 0.0 6.4e-146 485.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 VBB29786.1 - 0.066 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Glyco_hydro_6 PF01341.17 VBB29786.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 PrmA PF06325.13 VBB29787.1 - 9.2e-09 35.1 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 VBB29787.1 - 1.1e-08 34.8 0.0 1.9e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 VBB29787.1 - 1.6e-08 35.1 0.0 4.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB29787.1 - 4.7e-06 27.2 0.0 2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 VBB29787.1 - 8.8e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 VBB29787.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB29787.1 - 0.0012 19.5 0.0 0.0032 18.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 VBB29787.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 VBB29787.1 - 0.0016 18.4 0.1 0.0066 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB29787.1 - 0.0024 17.7 0.0 0.0063 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 VBB29787.1 - 0.0034 17.0 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GidB PF02527.15 VBB29787.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PRMT5_C PF17286.2 VBB29787.1 - 0.0073 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain TehB PF03848.14 VBB29787.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 VBB29787.1 - 0.023 13.8 0.0 0.08 12.0 0.0 1.7 1 1 1 2 2 2 0 DREV methyltransferase ICAT PF06384.11 VBB29788.1 - 0.0028 17.9 1.7 0.0098 16.1 0.0 2.8 3 0 0 3 3 3 1 Beta-catenin-interacting protein ICAT NfI_DNAbd_pre-N PF10524.9 VBB29789.1 - 2.8e-21 75.1 0.5 5e-21 74.3 0.5 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 VBB29789.1 - 2e-11 44.0 0.3 4.1e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 MH1 domain MCM6_C PF18263.1 VBB29790.1 - 0.04 14.2 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Collagen PF01391.18 VBB29791.1 - 6.1e-25 86.7 95.8 0.00019 21.1 15.2 4.0 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB29791.1 - 6.5e-11 42.1 1.3 9.2e-11 41.6 1.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain bZIP_1 PF00170.21 VBB29792.1 - 1.3e-09 38.0 15.6 1.3e-09 38.0 15.6 1.9 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 VBB29792.1 - 1.5e-07 31.4 14.8 1.5e-07 31.4 14.8 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 VBB29792.1 - 0.0001 22.7 11.1 0.0001 22.7 11.1 1.8 1 1 1 2 2 2 1 bZIP Maf transcription factor Spc29 PF17082.5 VBB29792.1 - 0.0021 17.9 1.9 0.0031 17.4 1.9 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 YabA PF06156.13 VBB29792.1 - 0.0066 17.1 1.6 0.0066 17.1 1.6 2.4 1 1 1 2 2 2 1 Initiation control protein YabA DMPK_coil PF08826.10 VBB29792.1 - 0.011 15.9 1.5 0.011 15.9 1.5 2.2 2 1 1 3 3 3 0 DMPK coiled coil domain like MCM_N PF14551.6 VBB29792.1 - 0.012 16.2 0.4 0.012 16.2 0.4 1.5 2 0 0 2 2 2 0 MCM N-terminal domain UPF0242 PF06785.11 VBB29792.1 - 0.026 14.6 6.7 0.057 13.5 6.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 VBB29792.1 - 0.17 12.2 2.2 0.89 9.9 1.0 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family APG6_N PF17675.1 VBB29792.1 - 0.54 10.8 11.6 0.99 9.9 11.6 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_S21 PF01165.20 VBB29792.1 - 4 7.2 10.1 2.6 7.8 6.1 2.4 1 1 0 2 2 2 0 Ribosomal protein S21 G2F PF07474.12 VBB29793.1 - 4.2e-58 196.2 0.0 1.1e-57 194.8 0.0 1.8 1 0 0 1 1 1 1 G2F domain NIDO PF06119.14 VBB29793.1 - 8.2e-13 49.1 4.9 9.3e-13 48.9 1.8 2.6 2 0 0 2 2 2 1 Nidogen-like EGF_CA PF07645.15 VBB29793.1 - 0.0013 18.9 5.2 0.0013 18.9 5.2 3.5 3 0 0 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.7 VBB29793.1 - 0.0087 16.2 9.9 0.0087 16.2 9.9 3.2 4 0 0 4 4 4 2 EGF domain cEGF PF12662.7 VBB29793.1 - 0.071 13.1 11.6 0.4 10.7 0.2 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF PF00008.27 VBB29793.1 - 0.42 11.0 26.8 0.05 13.9 7.9 3.4 3 1 0 3 3 3 0 EGF-like domain PRAS PF15798.5 VBB29793.1 - 1.8 9.2 4.5 0.39 11.3 0.6 1.9 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 ANAPC10 PF03256.16 VBB29794.1 - 5.6e-57 192.4 0.0 6.8e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 VBB29794.1 - 0.004 17.3 0.0 0.0079 16.3 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Pkinase PF00069.25 VBB29795.1 - 5.3e-52 176.8 0.0 1.4e-51 175.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29795.1 - 2.7e-24 85.8 0.0 7.3e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase TBPIP PF07106.13 VBB29795.1 - 7.8e-15 54.6 0.2 5.7e-14 51.8 0.1 2.7 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Kinase-like PF14531.6 VBB29795.1 - 1.6e-07 30.9 0.0 1.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 VBB29795.1 - 0.015 14.7 0.1 0.057 12.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB29795.1 - 0.027 14.4 0.0 0.1 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 VBB29795.1 - 0.066 12.8 3.2 0.15 11.6 0.0 2.8 2 2 1 4 4 4 0 RIO1 family DUF3704 PF12488.8 VBB29795.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Tnp_22_trimer PF17489.2 VBB29795.1 - 3.8 7.6 7.2 1.6 8.8 0.1 3.5 3 0 0 3 3 3 0 L1 transposable element trimerization domain Laminin_EGF PF00053.24 VBB29797.1 - 1.7e-20 72.9 36.4 5.1e-12 45.8 11.8 2.5 2 0 0 2 2 2 2 Laminin EGF domain GARP PF16731.5 VBB29797.1 - 0.0059 16.3 14.5 0.0059 16.3 14.5 5.4 1 1 5 6 6 6 1 Glutamic acid/alanine-rich protein of Trypanosoma DUF2935 PF11155.8 VBB29797.1 - 0.52 10.7 18.9 7.7e+03 -2.8 18.9 4.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) EGF_2 PF07974.13 VBB29797.1 - 2.8 8.4 26.3 0.4 11.1 6.8 3.4 2 2 1 3 3 3 0 EGF-like domain DASH_Dam1 PF08653.10 VBB29797.1 - 3.5 7.5 4.9 3.9 7.4 0.1 3.5 2 1 1 3 3 3 0 DASH complex subunit Dam1 Alanine_zipper PF11839.8 VBB29797.1 - 9.6 6.7 94.2 0.033 14.5 14.0 8.3 8 1 0 9 9 9 0 Alanine-zipper, major outer membrane lipoprotein Thioredoxin PF00085.20 VBB29798.1 - 1.5e-26 92.4 0.0 2.1e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 VBB29798.1 - 8.6e-06 26.2 0.0 3.1e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 VBB29798.1 - 6.4e-05 23.0 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 VBB29798.1 - 0.021 15.2 0.1 1.1 9.7 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 VBB29798.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Peptidase_C48 PF02902.19 VBB29799.1 - 4.5e-05 23.4 0.1 9.2e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Imm6 PF14434.6 VBB29799.1 - 0.033 14.1 1.5 1.3 9.0 0.0 3.0 3 1 1 4 4 4 0 Immunity protein Imm6 Cupin_8 PF13621.6 VBB29800.1 - 9.7e-46 156.5 0.0 1.4e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 VBB29800.1 - 4.6e-07 29.6 0.0 8.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 VBB29800.1 - 0.014 15.8 0.0 0.045 14.2 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase Acetyltransf_5 PF13444.6 VBB29800.1 - 0.071 13.8 0.1 0.2 12.4 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp PF00026.23 VBB29801.1 - 1.4e-70 238.2 0.0 1.7e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 VBB29801.1 - 2.8e-13 50.5 0.0 4.4e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 VBB29801.1 - 0.0029 17.4 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal dsDNA_bind PF01984.20 VBB29802.1 - 1.1e-26 93.3 8.4 1.2e-26 93.2 8.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.27 VBB29802.1 - 0.0063 17.0 0.2 0.021 15.3 0.1 1.7 1 1 1 2 2 2 1 PCI domain Lipoprotein_7 PF01540.16 VBB29802.1 - 0.028 13.7 1.5 0.034 13.4 1.5 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein FeoC PF09012.10 VBB29802.1 - 0.034 14.2 0.2 0.058 13.5 0.2 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator ALO PF04030.14 VBB29802.1 - 0.082 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Med18 PF09637.10 VBB29803.1 - 2.3e-26 93.2 0.0 1.5e-23 83.9 0.0 2.4 1 1 0 1 1 1 1 Med18 protein VRR_NUC PF08774.11 VBB29803.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 VRR-NUC domain UPF0184 PF03670.13 VBB29804.1 - 0.3 11.5 6.5 9.8 6.7 0.1 4.5 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0184) Astacin PF01400.24 VBB29805.1 - 1.5e-66 223.6 0.0 3.8e-66 222.4 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Fasciclin PF02469.22 VBB29805.1 - 1.7e-43 147.9 0.0 1.2e-19 70.8 0.0 5.4 4 1 0 4 4 4 4 Fasciclin domain CUB PF00431.20 VBB29805.1 - 1.8e-14 54.0 0.5 1.5e-13 51.0 0.1 2.3 2 0 0 2 2 2 1 CUB domain TSP_1 PF00090.19 VBB29805.1 - 1e-07 32.0 15.5 1e-07 32.0 15.5 2.7 3 0 0 3 3 3 1 Thrombospondin type 1 domain Peptidase_M66 PF10462.9 VBB29805.1 - 0.0067 15.4 0.2 0.012 14.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 VBB29805.1 - 0.025 14.5 1.0 0.69 9.7 0.3 2.5 1 1 1 2 2 2 0 Matrixin Reprolysin_3 PF13582.6 VBB29805.1 - 0.065 13.8 0.0 0.64 10.5 0.0 2.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF948 PF06103.11 VBB29806.1 - 0.29 11.4 2.7 0.7 10.2 2.7 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 VBB29806.1 - 1.3 8.6 4.3 2.1 7.8 4.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein UNC80 PF15778.5 VBB29807.1 - 1.6e-73 246.4 0.6 3.1e-73 245.4 0.6 1.5 1 0 0 1 1 1 1 Cation channel complex component UNC80 DUF3338 PF11819.8 VBB29807.1 - 0.014 15.4 2.2 0.039 13.9 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) RRM_1 PF00076.22 VBB29808.1 - 1.2e-12 47.5 0.2 3.9e-10 39.4 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 VBB29808.1 - 0.00021 21.9 19.6 0.00051 20.7 19.6 1.7 1 0 0 1 1 1 1 Glycine rich protein family RNA_bind PF08675.11 VBB29808.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA binding domain NAP PF00956.18 VBB29810.1 - 6.1e-86 287.9 4.8 7.4e-86 287.7 4.8 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Ground-like PF04155.18 VBB29811.1 - 1.8e-14 54.1 2.9 2.4e-14 53.7 2.9 1.2 1 0 0 1 1 1 1 Ground-like domain zf-C4 PF00105.18 VBB29813.1 - 1.6e-27 95.8 14.0 1.6e-27 95.8 14.0 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB29813.1 - 0.00071 19.2 4.4 0.0073 15.9 4.4 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor UDPGP PF01704.18 VBB29814.1 - 5.5e-33 114.2 0.0 6.9e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MlaC PF05494.12 VBB29814.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 MlaC protein NTP_transf_3 PF12804.7 VBB29814.1 - 0.025 14.9 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4123 PF13503.6 VBB29814.1 - 0.048 14.1 0.0 1.2 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4123) T4_baseplate PF12322.8 VBB29814.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Mito_carr PF00153.27 VBB29815.1 - 4.2e-48 161.2 6.2 8.5e-18 64.1 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Gpi1 PF05024.15 VBB29816.1 - 6.5e-34 117.7 11.2 1.5e-18 67.5 1.7 2.3 1 1 1 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Rhodanese PF00581.20 VBB29816.1 - 6.2e-07 29.9 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF1794 PF08768.11 VBB29817.1 - 5.4e-18 65.4 0.1 6.6e-18 65.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) p450 PF00067.22 VBB29818.1 - 2.4e-101 339.8 4.9 3e-101 339.5 0.0 2.2 2 1 0 2 2 2 1 Cytochrome P450 DUF148 PF02520.17 VBB29818.1 - 5.1e-08 33.0 7.9 1e-07 32.0 7.9 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF148 PIN_8 PF18476.1 VBB29818.1 - 1.1 9.1 7.6 0.16 11.8 3.3 1.8 2 0 0 2 2 2 0 PIN like domain Abhydrolase_1 PF00561.20 VBB29819.1 - 1.5e-10 41.1 0.0 7.7e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB29819.1 - 2.2e-10 40.2 0.0 5.9e-08 32.3 0.0 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 VBB29819.1 - 2.4e-07 31.6 0.0 3.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 VBB29819.1 - 4.1e-07 29.3 0.0 6.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 VBB29819.1 - 6e-07 29.5 0.2 5.5e-06 26.3 0.2 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1057 PF06342.12 VBB29819.1 - 2e-06 27.1 0.1 0.00092 18.3 0.0 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) Ser_hydrolase PF06821.13 VBB29819.1 - 6e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DLH PF01738.18 VBB29819.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 VBB29819.1 - 0.00014 21.4 0.0 0.00045 19.8 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 VBB29819.1 - 0.0021 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 VBB29819.1 - 0.0041 16.8 0.0 0.01 15.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Asp2 PF16929.5 VBB29819.1 - 0.0089 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Thioesterase PF00975.20 VBB29819.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 VBB29819.1 - 0.023 14.6 0.6 0.13 12.1 0.0 2.2 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2235 PF09994.9 VBB29819.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) PGAP1 PF07819.13 VBB29819.1 - 0.03 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein zf-CCCH PF00642.24 VBB29820.1 - 4.2e-17 61.6 13.5 1.3e-09 37.7 3.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB29820.1 - 4.4e-09 36.1 19.9 7.8e-05 22.6 4.4 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB29820.1 - 4.5e-05 23.1 14.9 0.013 15.2 4.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 VBB29820.1 - 0.0013 19.1 12.6 0.076 13.5 3.0 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 VBB29820.1 - 0.0075 17.0 9.9 0.55 10.9 1.6 2.5 1 1 1 2 2 2 2 Torus domain DUF3331 PF11811.8 VBB29820.1 - 0.039 13.8 0.1 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3331) GAD-like PF08887.11 VBB29820.1 - 0.14 11.9 0.2 2.3 8.0 0.0 2.2 1 1 1 2 2 2 0 GAD-like domain Neur_chan_LBD PF02931.23 VBB29823.1 - 0.0014 18.1 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain SNCAIP_SNCA_bd PF16700.5 VBB29824.1 - 1 9.2 5.8 0.4 10.4 2.4 2.1 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain CARD_2 PF16739.5 VBB29824.1 - 3.7 7.6 7.0 1.4 9.0 1.9 2.9 3 1 1 4 4 4 0 Caspase recruitment domain PID PF00640.23 VBB29825.1 - 1.6e-05 25.0 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) zf-C6H2 PF15801.5 VBB29826.1 - 0.0091 16.3 5.5 0.014 15.6 5.5 1.3 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Pex24p PF06398.11 VBB29827.1 - 0.067 12.2 0.1 0.079 11.9 0.1 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CRF1 PF10380.9 VBB29827.1 - 0.082 13.3 0.3 0.11 12.9 0.3 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 Pyridoxal_deC PF00282.19 VBB29828.1 - 9.1e-25 87.2 0.0 1.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 VBB29828.1 - 1.2e-08 34.3 0.0 2.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 VBB29828.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 VBB29828.1 - 0.17 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Gcd10p PF04189.13 VBB29828.1 - 0.19 10.8 0.1 0.38 9.8 0.1 1.4 1 0 0 1 1 1 0 Gcd10p family Nucleoporin_N PF08801.11 VBB29829.1 - 2.8e-68 230.7 0.3 5.8e-68 229.6 0.3 1.5 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 VBB29829.1 - 9.4e-17 61.0 3.5 1.4e-16 60.4 3.5 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal UPF0262 PF06793.12 VBB29829.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) LSM PF01423.22 VBB29830.1 - 4.5e-15 55.1 0.7 6.3e-15 54.6 0.5 1.3 1 1 0 1 1 1 1 LSM domain DUF3963 PF13124.6 VBB29830.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) ETC_C1_NDUFA5 PF04716.14 VBB29831.1 - 6.9e-21 73.8 0.4 1.4e-20 72.9 0.4 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region fn1 PF00039.18 VBB29832.1 - 0.02 15.1 0.8 0.02 15.1 0.8 1.9 2 0 0 2 2 2 0 Fibronectin type I domain Nuc_sug_transp PF04142.15 VBB29833.1 - 3.8e-120 400.8 24.0 4.3e-120 400.6 24.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 VBB29833.1 - 2.9e-07 30.8 2.6 2.9e-07 30.8 2.6 3.2 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.6 VBB29833.1 - 0.0046 16.6 8.8 0.017 14.7 8.6 2.0 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 VBB29833.1 - 0.019 14.2 29.1 0.095 11.9 29.1 2.0 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Multi_Drug_Res PF00893.19 VBB29833.1 - 0.021 15.5 1.1 0.021 15.5 1.1 4.2 2 2 1 4 4 4 0 Small Multidrug Resistance protein ATPase_gene1 PF09527.10 VBB29833.1 - 1.7 8.9 20.2 0.68 10.1 6.4 3.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Pkinase PF00069.25 VBB29834.1 - 5.7e-72 242.3 0.0 7.1e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29834.1 - 1.1e-43 149.4 0.0 1.6e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29834.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB29834.1 - 0.0032 16.9 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB29834.1 - 0.028 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 VBB29834.1 - 0.04 12.9 1.1 0.1 11.5 1.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_56 PF01630.18 VBB29835.1 - 3.8e-81 272.7 0.1 5.2e-81 272.2 0.1 1.0 1 0 0 1 1 1 1 Hyaluronidase Ploopntkinase2 PF18747.1 VBB29835.1 - 0.067 12.4 0.4 9.5 5.4 0.3 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 PUL PF08324.11 VBB29836.1 - 6.8e-17 61.6 1.2 7.7e-17 61.4 1.2 1.0 1 0 0 1 1 1 1 PUL domain Zona_pellucida PF00100.23 VBB29838.1 - 3.9e-08 33.4 0.1 1.3e-07 31.7 0.1 1.8 1 1 0 1 1 1 1 Zona pellucida-like domain ABC_membrane PF00664.23 VBB29841.1 - 4.3e-66 223.4 32.1 5.1e-42 144.4 6.2 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 VBB29841.1 - 1.1e-65 220.2 0.3 1.8e-31 109.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 VBB29841.1 - 1.4e-14 54.1 0.3 5.7e-05 22.7 0.0 3.8 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 VBB29841.1 - 9.1e-07 28.5 2.0 0.0092 15.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 VBB29841.1 - 1e-05 25.5 0.2 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 VBB29841.1 - 1e-05 24.5 0.1 0.036 12.9 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 VBB29841.1 - 1.3e-05 25.6 5.8 0.019 15.4 0.2 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 VBB29841.1 - 1.9e-05 24.9 5.3 0.018 15.3 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.6 VBB29841.1 - 7.3e-05 22.6 0.2 0.037 13.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 VBB29841.1 - 0.00015 22.3 0.1 0.041 14.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 VBB29841.1 - 0.00018 21.3 2.1 0.13 11.9 0.1 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 VBB29841.1 - 0.0002 21.8 0.2 0.73 10.3 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 VBB29841.1 - 0.00034 20.4 0.3 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 VBB29841.1 - 0.00038 20.6 5.5 0.66 10.2 0.6 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 VBB29841.1 - 0.0009 19.2 0.1 0.62 10.0 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 VBB29841.1 - 0.0024 17.6 0.8 1.4 8.6 0.0 3.4 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA_5 PF07728.14 VBB29841.1 - 0.0024 17.9 0.3 5.3 7.0 0.1 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 VBB29841.1 - 0.0027 16.9 0.0 0.084 12.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 VBB29841.1 - 0.003 17.2 0.0 2.6 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 VBB29841.1 - 0.0069 16.2 1.0 0.29 10.9 0.0 3.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 VBB29841.1 - 0.0078 16.4 0.2 6 7.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 VBB29841.1 - 0.019 15.0 0.9 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain APS_kinase PF01583.20 VBB29841.1 - 0.02 14.8 0.3 0.78 9.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_7 PF12775.7 VBB29841.1 - 0.033 13.7 0.1 6 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 VBB29841.1 - 0.036 14.0 1.9 2.2 8.1 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 VBB29841.1 - 0.038 14.5 0.2 3.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 VBB29841.1 - 0.044 13.4 0.5 6.2 6.4 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 VBB29841.1 - 0.053 13.9 0.3 18 5.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 VBB29841.1 - 0.054 13.7 1.9 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 VBB29841.1 - 0.061 13.4 0.8 10 6.3 0.2 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 VBB29841.1 - 0.098 12.6 1.0 16 5.4 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.6 VBB29841.1 - 0.11 12.2 0.2 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 VBB29841.1 - 0.22 11.3 0.9 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aa_trans PF01490.18 VBB29842.1 - 1.5e-41 142.5 21.2 7.1e-29 100.7 16.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 VBB29842.1 - 3e-10 39.7 4.2 3e-10 39.7 4.2 2.6 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family TMEM107 PF14995.6 VBB29842.1 - 0.0014 19.0 0.1 0.0014 19.0 0.1 3.1 1 1 3 4 4 4 1 Transmembrane protein DUF898 PF05987.13 VBB29842.1 - 0.61 9.1 10.5 1.1 8.2 9.8 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3040 PF11239.8 VBB29842.1 - 1 9.7 0.0 1 9.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Saf_2TM PF18303.1 VBB29842.1 - 1.3 8.6 7.3 0.83 9.2 0.3 2.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF5408 PF17402.2 VBB29842.1 - 1.6 8.7 4.3 0.99 9.3 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DeoC PF01791.9 VBB29843.1 - 2.5e-10 40.4 0.0 3.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase SPOC PF07744.13 VBB29844.1 - 2.5e-25 89.1 1.4 7.9e-25 87.5 0.1 2.6 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 VBB29844.1 - 2.1e-11 43.5 0.1 2.4e-06 27.2 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KOG2701 PF09762.9 VBB29845.1 - 5.7e-59 199.3 0.0 5.7e-59 199.3 0.0 2.7 3 1 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) RNase_HII PF01351.18 VBB29845.1 - 5.6e-46 156.9 4.3 5.7e-46 156.9 0.0 2.8 2 1 0 3 3 3 1 Ribonuclease HII Lipase_GDSL_3 PF14606.6 VBB29845.1 - 9.4 6.3 6.6 4.2 7.5 0.8 3.1 3 1 1 4 4 4 0 GDSL-like Lipase/Acylhydrolase family CLPTM1 PF05602.12 VBB29846.1 - 9.5e-102 341.2 4.9 4.5e-101 339.0 4.9 1.8 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) WD40_like PF17005.5 VBB29846.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PQ-loop PF04193.14 VBB29846.1 - 0.22 11.3 4.0 0.65 9.8 0.1 2.8 3 0 0 3 3 3 0 PQ loop repeat Laminin_G_2 PF02210.24 VBB29847.1 - 3.9e-57 192.3 0.1 2.5e-22 79.8 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 VBB29847.1 - 1.8e-42 144.6 0.0 1.1e-16 61.2 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain EGF PF00008.27 VBB29847.1 - 1.7e-05 25.0 20.0 0.0089 16.3 5.8 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 VBB29847.1 - 0.00056 20.5 20.2 0.1 13.2 6.6 2.7 2 0 0 2 2 2 2 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 VBB29847.1 - 0.021 15.1 4.8 0.46 10.8 1.3 2.7 2 1 0 2 2 2 0 Pvs28 EGF domain COMP PF11598.8 VBB29847.1 - 0.072 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein ABC1 PF03109.16 VBB29848.1 - 2e-33 115.1 0.0 4.3e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family SH3_1 PF00018.28 VBB29849.1 - 1.6e-64 213.3 9.0 2.1e-15 56.1 0.4 5.7 5 0 0 5 5 5 5 SH3 domain SH3_9 PF14604.6 VBB29849.1 - 9.2e-58 191.9 1.7 7.8e-13 48.1 0.0 6.6 6 0 0 6 6 6 5 Variant SH3 domain SH3_2 PF07653.17 VBB29849.1 - 2e-47 158.7 0.0 1.6e-09 37.3 0.0 6.0 5 1 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.20 VBB29849.1 - 1e-29 104.1 3.4 1e-29 104.1 3.4 2.7 3 0 0 3 3 3 1 RhoGEF domain EF-hand_4 PF12763.7 VBB29849.1 - 6e-28 96.8 0.0 1.6e-12 47.3 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 VBB29849.1 - 1.7e-26 92.9 0.0 1.7e-26 92.9 0.0 2.9 3 1 1 4 4 3 1 Pleckstrin homology domain Band_7 PF01145.25 VBB29849.1 - 4.3e-20 72.5 0.0 4.3e-20 72.5 0.0 3.8 2 2 2 4 4 2 1 SPFH domain / Band 7 family EF-hand_1 PF00036.32 VBB29849.1 - 1.8e-07 30.2 0.0 0.0015 17.9 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 VBB29849.1 - 2.7e-07 30.9 0.0 0.00093 19.6 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB29849.1 - 3.8e-05 23.3 0.1 0.6 10.2 0.0 3.6 4 0 0 4 4 3 2 EF-hand domain EF-hand_5 PF13202.6 VBB29849.1 - 0.0049 16.3 0.5 0.35 10.4 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 VBB29849.1 - 0.006 16.4 0.0 0.068 13.0 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair OpuAC PF04069.12 VBB29849.1 - 0.029 13.9 1.0 0.059 12.9 1.0 1.4 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system hSH3 PF14603.6 VBB29849.1 - 0.1 13.1 0.2 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_10 PF17902.1 VBB29849.1 - 0.15 12.1 0.4 4 7.6 0.0 3.1 3 0 0 3 3 3 0 SH3 domain ARID PF01388.21 VBB29850.1 - 8.2e-21 74.5 0.2 1.6e-20 73.6 0.2 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 VBB29851.1 - 2e-83 279.6 1.5 4.7e-83 278.4 0.2 2.0 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa E1-E2_ATPase PF00122.20 VBB29852.1 - 2.2e-13 50.1 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 VBB29852.1 - 4.2e-11 42.8 0.1 1.6e-09 37.7 0.0 3.1 2 1 1 3 3 3 1 Cation transport ATPase (P-type) PhoLip_ATPase_N PF16209.5 VBB29852.1 - 1.1e-07 31.5 2.9 1.1e-07 31.5 2.9 1.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 VBB29852.1 - 5.2e-07 30.2 0.2 1.9e-06 28.4 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UvrA_inter PF17760.1 VBB29852.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 UvrA interaction domain Pkinase PF00069.25 VBB29853.1 - 3.6e-68 229.8 0.0 4.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29853.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB29853.1 - 1.4e-06 27.9 0.0 6.8e-05 22.3 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 VBB29853.1 - 0.00051 19.4 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB29853.1 - 0.0029 17.6 0.1 0.029 14.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 VBB29853.1 - 0.064 12.1 0.4 0.11 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 VBB29853.1 - 0.083 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Death PF00531.22 VBB29854.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Death domain Mito_carr PF00153.27 VBB29855.1 - 2.1e-60 200.7 0.4 2e-19 69.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 VBB29855.1 - 0.00031 20.0 0.0 0.0011 18.2 0.0 1.9 2 1 0 2 2 2 1 Gammaproteobacterial serine protease FPN1 PF06963.12 VBB29856.1 - 0.039 12.5 0.4 0.047 12.3 0.4 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) GBP PF02263.19 VBB29858.1 - 8.7e-61 205.5 0.1 1.4e-60 204.8 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain DKCLD PF08068.12 VBB29858.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 DKCLD (NUC011) domain LRR_4 PF12799.7 VBB29859.1 - 7.7e-14 51.6 7.8 2.2e-07 31.1 1.2 3.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 VBB29859.1 - 1.2e-13 50.6 2.3 3.1e-09 36.4 1.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 VBB29859.1 - 0.0011 19.2 4.2 2.1 9.2 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 VBB29859.1 - 0.0067 15.9 1.1 0.012 15.1 0.6 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 VBB29859.1 - 0.05 13.7 0.1 0.05 13.7 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat RNase_Zc3h12a PF11977.8 VBB29860.1 - 7e-25 87.6 0.0 1.5e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain AAA_11 PF13086.6 VBB29860.1 - 0.13 12.0 3.8 0.23 11.2 3.8 1.4 1 0 0 1 1 1 0 AAA domain NOA36 PF06524.12 VBB29860.1 - 0.16 11.2 6.5 0.3 10.4 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1391 PF07151.12 VBB29860.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) V_ATPase_I PF01496.19 VBB29860.1 - 1.8 6.4 3.5 2.6 5.8 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPL5 PF18168.1 VBB29860.1 - 2.5 7.3 6.2 2.5 7.3 5.0 1.5 1 1 0 1 1 1 0 Prim-pol family 5 FAM176 PF14851.6 VBB29860.1 - 4.3 7.0 9.0 11 5.7 9.0 1.7 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 VBB29860.1 - 4.5 5.9 4.6 5.8 5.6 4.6 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 VBB29860.1 - 8.2 4.4 17.1 11 3.9 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4484 PF14831.6 VBB29860.1 - 9 6.3 8.6 11 6.0 7.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) ArfGap PF01412.18 VBB29861.1 - 7.2e-28 97.0 0.1 1.8e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GIT_CC PF16559.5 VBB29861.1 - 2.9e-22 78.3 0.7 8.2e-22 76.8 0.7 1.8 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor GIT_SHD PF08518.11 VBB29861.1 - 1.5e-18 66.1 6.1 4.4e-11 42.2 1.1 3.5 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 VBB29861.1 - 1.6e-06 28.2 5.0 1.6e-06 28.2 1.0 2.9 2 1 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Ank_4 PF13637.6 VBB29861.1 - 0.001 19.6 0.1 0.0042 17.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Phage_lysis PF03245.13 VBB29861.1 - 0.027 14.6 0.6 0.082 13.0 0.6 1.8 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein TolA_bind_tri PF16331.5 VBB29861.1 - 0.12 12.4 4.7 0.11 12.5 1.4 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation Ank PF00023.30 VBB29861.1 - 0.24 11.9 0.9 2.7 8.6 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat Baculo_PEP_C PF04513.12 VBB29861.1 - 0.49 10.4 3.5 1.9 8.5 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 VBB29861.1 - 4.6 7.4 8.8 0.51 10.5 2.0 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Vps16_N PF04841.13 VBB29862.1 - 4e-54 183.9 0.2 4.6e-54 183.7 0.2 1.0 1 0 0 1 1 1 1 Vps16, N-terminal region Ank_2 PF12796.7 VBB29863.1 - 1.5e-135 442.0 31.3 6.6e-16 58.7 0.1 12.3 4 3 8 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB29863.1 - 1.5e-106 347.5 20.2 2.5e-09 37.5 0.1 15.7 8 5 7 16 16 16 15 Ankyrin repeats (many copies) Ank PF00023.30 VBB29863.1 - 1.4e-99 322.5 47.4 2.1e-06 27.9 0.1 23.0 23 0 0 23 23 23 20 Ankyrin repeat Ank_3 PF13606.6 VBB29863.1 - 7.8e-89 280.9 32.2 5e-05 23.4 0.0 24.2 24 0 0 24 24 24 18 Ankyrin repeat Ank_5 PF13857.6 VBB29863.1 - 2.2e-77 254.1 42.5 2.7e-09 37.1 0.1 19.9 7 5 14 21 21 21 18 Ankyrin repeats (many copies) KH_1 PF00013.29 VBB29863.1 - 9.7e-13 47.8 0.7 2.5e-12 46.4 0.7 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 VBB29863.1 - 0.0074 16.1 0.1 0.031 14.2 0.1 2.1 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 VBB29863.1 - 0.061 13.2 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 KH domain A_deamin PF02137.18 VBB29865.1 - 6e-37 127.8 0.6 2.5e-26 92.9 0.1 2.9 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain dsrm PF00035.26 VBB29865.1 - 4.8e-26 91.2 4.7 4.6e-09 36.8 0.1 4.8 4 0 0 4 4 4 3 Double-stranded RNA binding motif Dicer_dimer PF03368.14 VBB29865.1 - 1e-06 28.8 1.6 4.6 7.5 0.1 4.6 4 0 0 4 4 4 3 Dicer dimerisation domain DND1_DSRM PF14709.7 VBB29865.1 - 0.026 14.8 0.5 8.2 6.8 0.0 3.8 4 0 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 WAC_Acf1_DNA_bd PF10537.9 VBB29865.1 - 0.45 11.1 2.8 8.7 6.9 0.1 2.8 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal TPR_2 PF07719.17 VBB29866.1 - 5.4e-13 48.0 0.3 0.0024 17.9 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB29866.1 - 1.7e-11 43.4 0.3 0.00022 20.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB29866.1 - 6.5e-08 32.1 1.0 4e-06 26.4 0.0 3.6 4 1 1 5 5 5 1 TPR repeat TPR_8 PF13181.6 VBB29866.1 - 4.1e-07 29.7 0.3 0.024 14.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29866.1 - 4.4e-07 29.8 0.1 1.8e-05 24.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29866.1 - 2.4e-06 27.9 0.1 0.00082 19.8 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB29866.1 - 6.6e-06 26.7 0.1 4.2e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29866.1 - 1.8e-05 24.9 0.1 0.00037 20.7 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29866.1 - 0.0001 22.8 0.0 0.0053 17.5 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29866.1 - 0.00052 20.2 0.0 0.0028 17.9 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB29866.1 - 0.017 15.7 0.2 42 5.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 VBB29866.1 - 0.27 11.2 0.8 9.9 6.2 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 VBB29867.1 - 1.1e-06 28.2 3.7 0.00012 21.7 0.1 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 VBB29867.1 - 5.9e-05 22.7 0.6 5.9e-05 22.7 0.6 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 VBB29867.1 - 0.001 19.6 0.3 1.9 9.3 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29867.1 - 0.0013 19.2 0.4 0.0029 18.1 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29867.1 - 0.0019 18.2 0.4 0.0019 18.2 0.4 4.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB29867.1 - 0.0045 17.6 0.4 0.062 14.0 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB29867.1 - 0.0055 16.6 0.5 0.024 14.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB29867.1 - 0.0089 16.2 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29867.1 - 0.014 15.8 0.0 0.047 14.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB29867.1 - 0.016 15.3 0.2 0.049 13.7 0.2 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 VBB29867.1 - 0.024 14.9 0.7 0.055 13.7 0.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 VBB29867.1 - 0.068 13.5 2.4 0.18 12.1 0.1 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF4752 PF15944.5 VBB29867.1 - 0.087 12.9 0.2 0.24 11.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) TPR_8 PF13181.6 VBB29867.1 - 5.8 7.4 8.6 1.4 9.3 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2281 PF10047.9 VBB29868.1 - 0.32 11.7 1.6 0.37 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) THP2 PF09432.10 VBB29869.1 - 0.27 11.3 4.9 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 Tho complex subunit THP2 Chromo_shadow PF01393.19 VBB29871.1 - 3.1e-09 36.8 0.2 6.3e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Chromo shadow domain Fibrinogen_BP PF08017.11 VBB29871.1 - 0.068 11.6 23.1 0.11 11.0 23.1 1.3 1 0 0 1 1 1 0 Fibrinogen binding protein Gp5_C PF06715.12 VBB29871.1 - 3.7 7.9 8.1 54 4.2 0.1 4.6 4 2 2 6 6 6 0 Gp5 C-terminal repeat (3 copies) JmjC PF02373.22 VBB29872.1 - 6e-40 136.2 3.2 8.4e-40 135.8 1.6 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase PLU-1 PF08429.11 VBB29872.1 - 6.4e-30 104.5 4.1 1.3e-29 103.4 4.1 1.6 1 0 0 1 1 1 1 PLU-1-like protein PHD PF00628.29 VBB29872.1 - 4.4e-15 55.3 52.6 8.5e-09 35.2 10.1 4.5 4 1 0 4 4 4 3 PHD-finger JmjN PF02375.17 VBB29872.1 - 6.6e-15 54.8 3.2 2.5e-14 52.9 3.2 2.1 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 VBB29872.1 - 2.3e-12 47.4 0.5 6.9e-12 45.9 0.5 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 VBB29872.1 - 1.4e-11 44.6 11.5 1.4e-11 44.6 11.5 2.9 2 0 0 2 2 2 1 C5HC2 zinc finger LSM PF01423.22 VBB29873.1 - 3.2e-19 68.4 0.0 3.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 VBB29873.1 - 0.014 15.5 0.2 0.021 14.9 0.1 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 VBB29873.1 - 0.016 15.4 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain RRM_9 PF18444.1 VBB29873.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif PBP PF01161.20 VBB29874.1 - 1.4e-18 67.5 0.0 1.6e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SNF2_N PF00176.23 VBB29875.1 - 2.7e-46 157.9 2.1 4.5e-46 157.2 2.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB29875.1 - 8.9e-14 51.8 0.0 6.4e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB29875.1 - 1.1e-11 45.1 0.3 6.2e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 VBB29875.1 - 1.4e-08 34.3 0.6 6e-08 32.2 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 VBB29875.1 - 0.079 12.2 0.1 0.079 12.2 0.1 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase YEATS PF03366.16 VBB29876.1 - 1.8e-22 79.1 0.1 3.1e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family AHD PF17793.1 VBB29876.1 - 8.4e-06 25.5 1.1 0.00014 21.6 1.1 2.5 1 1 0 1 1 1 1 ANC1 homology domain (AHD) YonK PF09642.10 VBB29876.1 - 0.055 13.6 1.3 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 YonK protein Ank_2 PF12796.7 VBB29877.1 - 7.2e-63 209.2 30.7 4.7e-14 52.7 0.3 7.2 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB29877.1 - 3.2e-52 174.2 18.8 1.2e-08 35.3 0.2 10.2 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB29877.1 - 6.8e-51 164.3 20.2 0.00031 20.9 0.0 14.3 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 VBB29877.1 - 1.9e-43 145.9 19.2 3.5e-09 36.7 0.1 10.6 5 4 7 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 VBB29877.1 - 2.2e-37 125.9 31.3 1.5e-05 25.2 0.2 13.8 14 0 0 14 14 14 9 Ankyrin repeat AnkUBD PF18418.1 VBB29877.1 - 0.0062 16.6 0.0 3.9 7.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin ubiquitin-binding domain DUF1699 PF08004.11 VBB29877.1 - 0.082 12.6 0.2 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) DUF3447 PF11929.8 VBB29877.1 - 1.3 9.0 3.3 1.1 9.3 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Trehalase PF01204.18 VBB29878.1 - 1.4e-160 535.5 0.0 1.7e-160 535.2 0.0 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 VBB29878.1 - 0.00012 21.1 0.0 0.00058 18.9 0.0 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.16 VBB29878.1 - 0.0085 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain PQQ_3 PF13570.6 VBB29879.1 - 0.022 15.2 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Phage_integrase PF00589.22 VBB29879.1 - 0.025 14.4 0.4 0.38 10.5 0.3 2.2 2 0 0 2 2 2 0 Phage integrase family PQQ_2 PF13360.6 VBB29879.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 VBB29879.1 - 0.086 13.2 0.1 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 VBB29880.1 - 2e-85 283.8 0.0 5.9e-47 159.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB29880.1 - 3.1e-22 78.1 1.2 5.1e-10 39.0 0.8 3.1 2 1 0 2 2 2 2 AAA+ lid domain Nucleolin_bd PF16725.5 VBB29880.1 - 6.6e-17 60.9 0.1 1.4e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Nucleolin binding domain AAA_16 PF13191.6 VBB29880.1 - 1.3e-09 38.6 1.3 0.0058 17.0 0.0 4.1 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 VBB29880.1 - 9.6e-09 35.2 0.0 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB29880.1 - 1.5e-08 35.0 3.9 0.002 18.4 0.0 5.1 3 2 1 4 4 4 2 AAA domain AAA_2 PF07724.14 VBB29880.1 - 2.7e-08 34.1 0.0 8.3e-05 22.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 VBB29880.1 - 2.9e-08 34.0 0.0 0.001 19.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 VBB29880.1 - 3e-07 30.5 0.6 0.06 13.3 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 VBB29880.1 - 3.5e-07 30.1 0.1 0.015 15.0 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 VBB29880.1 - 1.2e-06 28.8 0.0 0.077 13.4 0.0 3.7 2 2 0 2 2 2 2 RNA helicase TIP49 PF06068.13 VBB29880.1 - 1.3e-06 27.8 0.3 0.0028 16.9 0.0 2.8 3 0 0 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 VBB29880.1 - 5.6e-06 25.9 0.3 0.059 12.7 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 VBB29880.1 - 8.9e-06 25.8 0.0 0.0058 16.6 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain Vps4_C PF09336.10 VBB29880.1 - 1.2e-05 25.2 0.1 0.28 11.2 0.1 2.9 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 VBB29880.1 - 1.4e-05 25.1 0.0 0.025 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 VBB29880.1 - 1.9e-05 25.2 0.0 0.019 15.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 VBB29880.1 - 2.1e-05 23.9 0.2 0.0086 15.4 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin NACHT PF05729.12 VBB29880.1 - 5.7e-05 23.1 1.7 0.27 11.1 0.2 3.5 3 1 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 VBB29880.1 - 5.8e-05 23.4 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 VBB29880.1 - 0.0002 21.4 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 VBB29880.1 - 0.00028 21.4 0.8 0.66 10.5 0.0 4.0 4 2 0 4 4 4 1 ABC transporter ATPase PF06745.13 VBB29880.1 - 0.00035 20.0 2.9 0.67 9.3 0.0 3.6 3 1 0 4 4 4 2 KaiC AAA_17 PF13207.6 VBB29880.1 - 0.00058 20.3 0.0 1.7 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 VBB29880.1 - 0.00086 19.2 0.0 0.88 9.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 VBB29880.1 - 0.0014 18.4 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 VBB29880.1 - 0.0016 17.6 0.0 1.3 8.1 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 VBB29880.1 - 0.0025 17.4 0.1 2.4 7.7 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_25 PF13481.6 VBB29880.1 - 0.0049 16.5 0.6 5.6 6.5 0.0 3.3 2 1 1 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 VBB29880.1 - 0.006 16.7 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activat PF00158.26 VBB29880.1 - 0.0091 15.7 0.0 3.8 7.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 VBB29880.1 - 0.0097 16.0 0.0 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 VBB29880.1 - 0.011 15.6 0.3 2.2 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 VBB29880.1 - 0.027 14.2 0.1 5.9 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 VBB29880.1 - 0.049 13.1 0.1 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Acyl_transf_1 PF00698.21 VBB29882.1 - 8.8e-71 239.0 0.0 1.4e-70 238.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 VBB29882.1 - 9.3e-69 231.8 0.0 1.6e-68 231.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 VBB29882.1 - 1.8e-44 151.8 0.8 8.2e-43 146.4 0.0 3.5 4 0 0 4 4 4 1 KR domain Ketoacyl-synt_C PF02801.22 VBB29882.1 - 2.2e-40 137.3 0.0 4.3e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 VBB29882.1 - 1.1e-31 109.6 0.0 2.7e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 VBB29882.1 - 1.8e-15 57.1 0.1 4.3e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 VBB29882.1 - 1.8e-15 58.2 0.0 3.9e-13 50.6 0.0 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PS-DH PF14765.6 VBB29882.1 - 2.1e-13 50.2 0.0 4.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 VBB29882.1 - 3.5e-07 30.5 1.4 5.5e-07 29.9 0.1 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site adh_short PF00106.25 VBB29882.1 - 1.4e-06 27.9 0.3 0.0011 18.4 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_23 PF13489.6 VBB29882.1 - 0.0011 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 VBB29882.1 - 0.004 16.5 0.0 0.0093 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_PK PF05891.12 VBB29882.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 VBB29882.1 - 0.0088 15.4 0.2 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase domain ACP_syn_III PF08545.10 VBB29882.1 - 0.056 13.3 0.7 0.15 12.0 0.7 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 VBB29885.1 - 1.3e-33 114.5 17.3 2.7e-05 24.8 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat PRP4 PF08799.11 VBB29885.1 - 2.5e-11 42.9 1.3 2.5e-11 42.9 1.3 2.6 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 VBB29885.1 - 3.6e-07 30.4 0.1 0.13 12.6 0.0 5.5 3 1 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB29885.1 - 0.0045 16.9 0.0 3.4 7.5 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A NOB1_Zn_bind PF08772.11 VBB29886.1 - 3.3e-28 97.6 0.1 6.5e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 VBB29886.1 - 9.4e-24 83.7 0.0 2e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease DZR PF12773.7 VBB29886.1 - 0.039 14.0 0.4 0.073 13.1 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon BpuJI_N PF11564.8 VBB29886.1 - 0.099 11.8 0.6 0.16 11.1 0.6 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal zf-RING_2 PF13639.6 VBB29887.1 - 1e-12 48.2 8.6 1e-12 48.2 8.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 VBB29887.1 - 4.6e-10 39.6 6.7 1.1e-09 38.4 6.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 VBB29887.1 - 1.5e-09 37.5 8.4 1.5e-09 37.5 8.4 1.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB29887.1 - 6.7e-08 32.4 1.9 6.7e-08 32.4 1.9 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 VBB29887.1 - 1e-07 31.5 4.9 1e-07 31.5 4.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 VBB29887.1 - 2.3e-07 31.0 4.2 6.3e-07 29.5 0.3 2.8 3 0 0 3 3 3 1 zinc-ribbon zf-RING_5 PF14634.6 VBB29887.1 - 4.3e-07 29.8 6.8 4.3e-07 29.8 6.8 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB29887.1 - 2e-06 27.6 4.4 2e-06 27.6 4.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB29887.1 - 3e-06 27.0 8.2 3e-06 27.0 8.2 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB29887.1 - 4.2e-06 26.7 3.4 8.4e-06 25.8 3.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 VBB29887.1 - 2.6e-05 24.0 4.6 2.6e-05 24.0 4.6 1.9 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 VBB29887.1 - 0.00079 19.0 4.9 0.00079 19.0 4.9 2.3 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 VBB29887.1 - 0.019 14.9 0.9 0.019 14.9 0.9 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 VBB29887.1 - 0.032 14.5 5.6 0.032 14.5 5.6 2.1 2 0 0 2 2 2 0 RING-like domain zf-Nse PF11789.8 VBB29887.1 - 0.062 13.1 4.3 0.14 12.0 4.3 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.12 VBB29887.1 - 0.14 12.2 8.4 3.1 7.8 0.2 2.6 2 1 1 3 3 3 0 zinc-ribbons RINGv PF12906.7 VBB29887.1 - 0.16 12.1 7.6 0.37 11.0 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-FPG_IleRS PF06827.14 VBB29887.1 - 0.22 11.4 4.9 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS TF_Zn_Ribbon PF08271.12 VBB29887.1 - 0.26 10.8 6.1 0.32 10.5 1.9 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 VBB29887.1 - 0.33 10.6 7.5 7.7 6.2 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_16 PF17034.5 VBB29887.1 - 0.35 11.1 4.0 0.17 12.1 1.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon like family Zf_RING PF16744.5 VBB29887.1 - 1.9 8.6 7.3 0.19 11.9 2.5 1.9 2 0 0 2 2 1 0 KIAA1045 RING finger zf-RING_6 PF14835.6 VBB29887.1 - 2.3 8.1 5.1 0.43 10.5 0.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 VBB29887.1 - 4.7 7.5 10.7 1.8 8.8 6.3 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain C1_1 PF00130.22 VBB29887.1 - 7.4 6.5 13.4 0.81 9.6 2.5 3.0 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1744 PF08490.12 VBB29888.1 - 1.3e-95 320.3 0.0 1.9e-95 319.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 VBB29888.1 - 6.9e-52 176.6 0.3 3.1e-51 174.5 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 VBB29888.1 - 2.1e-13 49.8 3.0 1.1e-08 34.3 0.2 4.1 4 1 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 VBB29888.1 - 9e-09 35.3 0.2 4e-08 33.2 0.2 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 VBB29888.1 - 1.2e-05 25.4 0.0 8.6e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 RNase_H superfamily Archease PF01951.16 VBB29888.1 - 0.065 13.5 0.1 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) CpXC PF14353.6 VBB29888.1 - 0.4 10.7 3.7 1.3 9.1 3.7 1.8 1 0 0 1 1 1 0 CpXC protein adh_short PF00106.25 VBB29889.1 - 6.1e-31 107.4 0.0 1.6e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB29889.1 - 2.1e-18 66.8 0.0 3.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB29889.1 - 0.00062 19.7 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 VBB29889.1 - 0.025 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Spo0A_C PF08769.11 VBB29890.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Patched PF02460.18 VBB29891.1 - 2.9e-200 667.4 10.4 4.3e-200 666.8 10.4 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB29891.1 - 4.4e-33 114.3 2.2 4.4e-33 114.3 2.2 3.4 4 1 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 VBB29891.1 - 1.9e-05 22.6 0.6 1.9e-05 22.6 0.6 1.9 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 VBB29891.1 - 0.0036 16.7 2.1 0.0036 16.7 2.1 2.5 2 0 0 2 2 2 1 Protein export membrane protein Peptidase_S48 PF03574.15 VBB29891.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S48 DB PF01682.19 VBB29892.1 - 6.5e-17 61.7 14.2 1.1e-16 60.9 14.2 1.4 1 0 0 1 1 1 1 DB module Mlf1IP PF10248.9 VBB29894.1 - 6.4e-38 130.4 3.1 1e-37 129.8 3.1 1.2 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Med13_C PF06333.12 VBB29896.1 - 2.6e-93 312.9 0.1 2.6e-93 312.9 0.1 2.9 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 VBB29896.1 - 8.7e-30 104.3 0.0 1.3e-27 97.2 0.0 2.7 2 0 0 2 2 2 2 MID domain of medPIWI Med13_N PF11597.8 VBB29896.1 - 2.8e-25 89.4 1.3 6e-25 88.3 1.3 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal WD40 PF00400.32 VBB29898.1 - 2.4e-27 94.6 0.1 0.00032 21.4 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CSTF1_dimer PF16699.5 VBB29898.1 - 4.6e-23 80.7 0.1 8.2e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 VBB29898.1 - 2.5e-14 53.3 0.0 0.0074 16.6 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB29898.1 - 1e-05 25.5 0.0 0.023 14.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 VBB29898.1 - 3.6e-05 22.9 0.1 0.03 13.3 0.0 2.4 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 VBB29898.1 - 0.011 14.1 0.0 0.031 12.6 0.0 1.7 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 VBB29898.1 - 0.05 12.2 0.3 22 3.5 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 VBB29898.1 - 0.089 11.3 0.0 0.17 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain HPS3_N PF14761.6 VBB29898.1 - 0.16 11.5 0.1 0.95 9.0 0.0 2.1 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 Fes1 PF08609.10 VBB29899.1 - 0.00012 22.9 0.6 0.00028 21.7 0.6 1.6 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 SEFIR PF08357.11 VBB29900.1 - 6.7e-17 62.2 0.1 1.5e-16 61.0 0.1 1.6 1 0 0 1 1 1 1 SEFIR domain zf-C2H2_4 PF13894.6 VBB29900.1 - 1.4e-14 53.5 47.2 0.0043 17.8 1.5 8.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB29900.1 - 1.4e-11 44.2 56.0 0.0048 17.3 0.6 8.3 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-met PF12874.7 VBB29900.1 - 0.00048 20.4 11.0 0.0021 18.4 0.1 5.3 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 VBB29900.1 - 0.0055 16.7 19.8 0.042 13.9 0.0 5.2 4 1 1 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB29900.1 - 0.063 13.6 17.3 1 9.7 0.0 5.5 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding YjbT PF17089.5 VBB29900.1 - 0.12 12.4 0.3 3 7.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family zf-H2C2_5 PF13909.6 VBB29900.1 - 0.49 10.2 21.3 0.17 11.7 4.1 5.5 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 VBB29900.1 - 3.2 8.2 28.1 12 6.2 9.6 5.3 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 VBB29900.1 - 3.9 7.5 9.5 2.2 8.3 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 VBB29900.1 - 5.6 7.0 9.0 4.5 7.3 0.2 4.1 2 2 1 4 4 4 0 CpXC protein ACBP PF00887.19 VBB29901.1 - 1.2e-08 35.0 1.0 1.2e-08 35.0 1.0 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein P21-Arc PF04062.14 VBB29902.1 - 5.4e-68 228.4 1.5 1.5e-66 223.8 1.5 2.2 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit PH PF00169.29 VBB29902.1 - 2e-07 31.5 0.2 1e-06 29.2 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 VBB29902.1 - 0.031 14.1 0.0 0.089 12.6 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 VBB29902.1 - 0.039 14.3 0.1 0.35 11.2 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Glyco_transf_41 PF13844.6 VBB29903.1 - 6.6e-261 865.6 0.0 8.8e-261 865.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 VBB29903.1 - 1.4e-70 230.4 19.6 2.3e-08 33.5 0.0 10.4 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 VBB29903.1 - 9.9e-65 214.0 25.6 5e-11 42.1 0.1 9.4 2 2 7 9 9 9 9 TPR repeat TPR_2 PF07719.17 VBB29903.1 - 6.3e-52 169.6 14.4 1.1e-06 28.2 0.1 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29903.1 - 7.2e-52 170.1 21.0 1.2e-05 25.3 0.2 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 VBB29903.1 - 1e-42 140.8 10.9 4.5e-05 23.3 0.2 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 VBB29903.1 - 2.7e-34 117.3 22.6 8.2e-11 42.0 1.8 6.2 4 1 3 7 7 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 VBB29903.1 - 7.8e-32 109.7 0.7 2.2e-08 34.6 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 VBB29903.1 - 1.5e-29 100.1 3.3 0.0044 17.7 0.0 9.4 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 VBB29903.1 - 1e-25 87.8 4.2 0.00068 19.5 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29903.1 - 1.2e-25 89.8 13.3 1.1e-06 29.0 0.0 5.5 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 VBB29903.1 - 1.6e-25 88.2 25.1 9.1e-06 25.4 0.3 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_9 PF13371.6 VBB29903.1 - 2.7e-10 40.2 2.3 0.051 13.7 0.0 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 VBB29903.1 - 7.7e-09 35.6 6.2 0.68 10.7 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 VBB29903.1 - 1.4e-08 34.2 0.8 0.05 12.5 0.0 4.1 1 1 2 4 4 4 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 VBB29903.1 - 7.7e-08 32.1 4.1 0.00075 19.0 0.0 3.3 1 1 1 2 2 2 2 MalT-like TPR region EST1_DNA_bind PF10373.9 VBB29903.1 - 2.9e-06 27.0 7.5 0.02 14.4 0.1 3.9 3 1 1 4 4 4 3 Est1 DNA/RNA binding domain FAT PF02259.23 VBB29903.1 - 5.9e-06 25.7 0.1 1.7 7.8 0.3 5.2 2 2 4 6 6 6 2 FAT domain TPR_3 PF07720.12 VBB29903.1 - 3.5e-05 23.7 0.6 0.49 10.4 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 VBB29903.1 - 6.1e-05 22.4 0.3 0.12 11.6 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 VBB29903.1 - 0.00045 20.2 9.6 7.4 6.7 0.3 6.3 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 VBB29903.1 - 0.0017 18.8 1.0 4.3 7.8 0.1 3.3 1 1 3 4 4 4 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 VBB29903.1 - 0.0092 16.5 0.0 24 5.9 0.1 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB29903.1 - 0.018 15.3 11.4 0.34 11.1 3.4 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 VBB29903.1 - 0.045 13.5 1.0 5.7 6.6 0.0 3.4 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 VBB29903.1 - 0.13 11.9 7.0 5.2 6.7 4.4 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain Mad3_BUB1_I PF08311.12 VBB29903.1 - 0.52 10.3 7.2 21 5.1 0.2 5.2 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 TPR_20 PF14561.6 VBB29903.1 - 4 7.9 7.1 40 4.6 0.2 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat E2_bind PF08825.10 VBB29904.1 - 0.068 13.3 0.4 0.13 12.4 0.3 1.5 1 1 0 1 1 1 0 E2 binding domain DUF1635 PF07795.11 VBB29904.1 - 0.28 11.0 3.3 0.28 11.0 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Utp14 PF04615.13 VBB29905.1 - 2.5e-110 370.3 65.3 3.9e-110 369.7 65.3 1.2 1 0 0 1 1 1 1 Utp14 protein HGTP_anticodon PF03129.20 VBB29905.1 - 1.3e-16 60.5 3.1 2.7e-16 59.5 0.1 3.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 VBB29905.1 - 9.3e-16 58.3 0.0 2.7e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 VBB29905.1 - 3.4e-12 46.4 0.0 1.4e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HLH PF00010.26 VBB29906.1 - 4.1e-11 42.7 0.1 8.6e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain F-box-like PF12937.7 VBB29906.1 - 8.3e-07 28.8 0.7 1.8e-06 27.7 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB29906.1 - 0.0002 21.2 1.3 0.00044 20.1 1.3 1.6 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 VBB29908.1 - 2.5e-45 152.1 41.5 1e-08 34.8 11.2 7.8 5 2 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 VBB29908.1 - 1.9e-32 110.7 50.9 2.1e-06 28.0 1.1 8.5 4 1 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB29908.1 - 7.5e-10 38.0 42.6 3.5 8.5 0.7 13.3 14 0 0 14 14 14 5 Leucine Rich Repeat LRR_5 PF13306.6 VBB29908.1 - 0.0033 17.4 0.2 3.1 7.8 0.1 2.7 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 VBB29908.1 - 0.13 12.4 50.1 0.32 11.2 0.0 11.7 13 0 0 13 13 13 0 Leucine Rich repeat LEDGF PF11467.8 VBB29908.1 - 0.21 11.2 1.5 6.9 6.3 0.0 3.1 2 1 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) Med27 PF11571.8 VBB29909.1 - 2.1e-13 50.4 1.0 7.2e-13 48.7 1.0 2.0 1 0 0 1 1 1 1 Mediator complex subunit 27 p450 PF00067.22 VBB29910.1 - 5.5e-75 252.9 2.2 1.9e-74 251.1 2.2 1.8 1 1 0 1 1 1 1 Cytochrome P450 zf-RING_5 PF14634.6 VBB29910.1 - 8.7e-09 35.2 13.3 3e-08 33.5 13.3 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB29910.1 - 3.4e-08 33.4 6.3 3.4e-08 33.4 6.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB29910.1 - 5.4e-08 32.6 12.7 1.6e-07 31.1 12.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB29910.1 - 1.3e-06 28.5 14.1 3.2e-06 27.2 14.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 VBB29910.1 - 1.6e-06 28.4 12.5 6e-06 26.5 12.5 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 VBB29910.1 - 2.9e-05 23.8 9.5 8.3e-05 22.4 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB29910.1 - 7.1e-05 22.6 11.6 0.00027 20.7 11.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB29910.1 - 0.00064 19.7 2.7 0.003 17.6 2.7 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Anti-TRAP PF15777.5 VBB29910.1 - 0.028 14.4 0.7 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Prok-RING_4 PF14447.6 VBB29910.1 - 0.62 10.0 13.8 5.3 7.0 13.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 VBB29910.1 - 0.85 9.8 8.3 3.4 7.9 8.3 2.1 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.7 VBB29910.1 - 1.7 9.0 8.7 7.7 6.9 8.7 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 VBB29910.1 - 4.7 7.1 12.6 0.027 14.3 2.5 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 VBB29911.1 - 7.9e-31 105.6 12.1 1.1e-05 26.1 0.3 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ATG16 PF08614.11 VBB29911.1 - 3.6e-14 53.5 25.9 3.8e-13 50.1 25.9 2.1 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 VBB29911.1 - 1.3e-13 51.1 0.1 0.0008 19.7 0.0 4.6 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 VBB29911.1 - 0.00042 19.1 2.7 0.23 10.1 0.2 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB29911.1 - 0.0033 16.8 0.3 0.3 10.3 0.0 3.3 1 1 1 3 3 3 1 WD40-like domain Occludin_ELL PF07303.13 VBB29911.1 - 0.014 16.1 0.0 0.014 16.1 0.0 2.5 2 0 0 2 2 2 0 Occludin homology domain FAM76 PF16046.5 VBB29911.1 - 1.1 8.5 17.4 6.5 6.0 11.6 2.3 1 1 1 2 2 2 0 FAM76 protein KELK PF15796.5 VBB29911.1 - 1.6 9.2 25.4 0.12 12.8 12.2 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LAM_C PF12544.8 VBB29911.1 - 2.6 8.3 5.5 10 6.3 4.0 2.4 1 1 1 2 2 2 0 Lysine-2,3-aminomutase Pkinase PF00069.25 VBB29912.1 - 6e-59 199.6 0.0 1.4e-58 198.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29912.1 - 7.7e-30 104.0 0.2 2.8e-29 102.2 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB29912.1 - 0.00024 21.1 0.1 0.0021 18.0 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 VBB29912.1 - 0.00058 18.9 0.2 0.0009 18.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 VBB29912.1 - 0.0054 16.1 0.9 0.0095 15.3 0.9 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB29912.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 VBB29912.1 - 0.075 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 VBB29912.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Forkhead PF00250.18 VBB29914.1 - 4.4e-37 126.2 0.1 8.6e-37 125.3 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain GAGBD PF16828.5 VBB29914.1 - 0.039 14.1 0.3 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 GAG-binding domain on surface antigen Sec1 PF00995.23 VBB29915.1 - 3.1e-82 277.7 0.1 8.3e-82 276.2 0.0 1.7 2 0 0 2 2 2 1 Sec1 family PARP PF00644.20 VBB29915.1 - 1.5e-49 168.3 0.0 3.7e-49 167.0 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 VBB29915.1 - 2.1e-40 138.0 0.4 5.5e-40 136.6 0.4 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 VBB29915.1 - 1.7e-25 88.9 1.5 3.4e-25 87.9 1.5 1.6 1 0 0 1 1 1 1 WGR domain WWE PF02825.20 VBB29915.1 - 6.9e-08 33.0 0.1 0.0013 19.3 0.1 2.8 2 0 0 2 2 2 2 WWE domain BORCS6 PF10157.9 VBB29915.1 - 0.42 10.8 3.9 0.15 12.3 0.2 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 7TM_GPCR_Srw PF10324.9 VBB29917.1 - 7.2e-05 22.2 12.9 0.055 12.7 5.3 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 VBB29917.1 - 0.0017 17.7 6.1 0.0023 17.3 6.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) adh_short PF00106.25 VBB29918.1 - 1e-05 25.1 0.2 1.8e-05 24.3 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB29918.1 - 5.5e-05 22.8 0.1 6.8e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 VBB29918.1 - 0.0057 16.1 0.1 0.02 14.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hpt PF01627.23 VBB29918.1 - 0.051 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Hpt domain SHQ1 PF04925.15 VBB29919.1 - 3.4e-53 179.8 1.4 4.8e-53 179.3 1.4 1.2 1 0 0 1 1 1 1 SHQ1 protein Adaptin_N PF01602.20 VBB29920.1 - 1.6e-135 452.7 7.9 2.2e-135 452.2 7.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3D1 PF06375.11 VBB29920.1 - 1e-31 110.3 11.5 1e-31 110.3 11.5 3.5 3 1 1 4 4 4 1 AP-3 complex subunit delta-1 Cnd1 PF12717.7 VBB29920.1 - 7.5e-15 55.3 0.1 3.2e-11 43.6 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 VBB29920.1 - 3.5e-06 27.2 1.0 0.09 13.0 0.0 3.7 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 VBB29920.1 - 8.6e-06 25.6 2.0 3.3 8.2 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 VBB29920.1 - 4.8e-05 23.7 0.1 0.76 10.2 0.0 4.0 3 1 2 5 5 5 3 HEAT repeats RasGEF_N_2 PF14663.6 VBB29920.1 - 0.019 15.4 0.0 1.1 9.7 0.0 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 VBB29920.1 - 0.073 13.7 0.4 0.62 10.7 0.1 2.8 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Elongin_A PF06881.11 VBB29921.1 - 0.029 14.9 0.1 0.049 14.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TruD PF01142.18 VBB29922.1 - 3.8e-64 217.1 0.0 5.9e-61 206.5 0.0 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) PI-PLC-X PF00388.19 VBB29923.1 - 0.0035 16.9 0.0 0.0071 15.9 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TBCC PF07986.12 VBB29924.1 - 4.9e-40 136.0 3.4 7.1e-40 135.5 3.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 VBB29924.1 - 0.053 13.1 0.4 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF5041 PF16444.5 VBB29925.1 - 0.0019 18.5 0.1 0.0029 17.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5041) Ints3 PF10189.9 VBB29926.1 - 8.3e-45 152.8 0.4 2.9e-44 151.0 0.4 2.0 1 0 0 1 1 1 1 Integrator complex subunit 3 adh_short PF00106.25 VBB29927.1 - 1.4e-20 73.6 0.0 6.4e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 VBB29927.1 - 1.3e-09 38.0 0.0 3.9e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 VBB29927.1 - 3.2e-07 30.1 0.0 5.7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 VBB29927.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 VBB29927.1 - 4.3e-05 23.5 0.0 0.00012 22.0 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 VBB29927.1 - 4.8e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 VBB29927.1 - 5.6e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 VBB29927.1 - 0.0031 16.7 0.0 0.033 13.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 VBB29927.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 VBB29927.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 VBB29927.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 VBB29927.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HECT PF00632.25 VBB29928.1 - 4.2e-100 335.2 0.0 6.3e-100 334.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 VBB29928.1 - 6.7e-27 93.3 4.5 7.1e-13 48.4 0.1 3.0 3 0 0 3 3 3 2 WW domain C2 PF00168.30 VBB29928.1 - 2.3e-19 69.6 0.0 4.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 VBB29929.1 - 1.3e-23 80.7 17.1 0.00048 19.5 0.5 6.5 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 VBB29929.1 - 4.4e-23 81.5 17.1 1.4e-08 35.0 1.6 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 VBB29929.1 - 2.2e-17 62.6 12.0 8e-05 22.4 0.4 5.4 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.6 VBB29929.1 - 2e-16 58.4 16.3 0.00097 18.9 0.1 6.7 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 VBB29929.1 - 8.8e-15 53.4 15.4 0.0014 18.0 0.1 6.3 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.9 VBB29929.1 - 1.3e-06 28.7 10.1 0.0052 17.1 0.4 3.8 3 1 1 4 4 4 4 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 VBB29929.1 - 0.012 15.5 7.2 14 5.6 0.4 4.6 4 1 1 5 5 5 0 EF hand DUF1636 PF07845.11 VBB29929.1 - 0.062 13.7 0.0 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) Excalibur PF05901.11 VBB29929.1 - 2.3 8.9 6.9 2.3 8.9 0.2 3.5 3 0 0 3 3 3 0 Excalibur calcium-binding domain MCM PF00493.23 VBB29930.1 - 2.2e-101 337.6 0.2 2.6e-100 334.1 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 VBB29930.1 - 6.3e-39 132.7 0.2 1.5e-38 131.5 0.1 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 VBB29930.1 - 3.5e-23 81.8 0.1 9.5e-23 80.4 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 VBB29930.1 - 6.5e-10 38.7 0.0 2.7e-06 26.9 0.0 2.9 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB29930.1 - 4.1e-09 36.5 0.0 1.5e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 VBB29930.1 - 4.7e-09 36.8 1.3 4.7e-09 36.8 1.3 3.7 3 1 0 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.11 VBB29930.1 - 4e-05 23.5 0.0 0.00014 21.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.13 VBB29930.1 - 0.00062 19.8 0.5 0.0044 17.0 0.2 2.2 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Sigma54_activat PF00158.26 VBB29930.1 - 0.0013 18.4 0.0 0.79 9.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Med31 PF05669.12 VBB29930.1 - 0.0019 18.1 1.4 0.015 15.3 1.2 2.3 2 0 0 2 2 2 1 SOH1 AAA PF00004.29 VBB29930.1 - 0.037 14.4 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0184 PF03670.13 VBB29930.1 - 3.8 8.0 5.1 3.9 7.9 0.1 2.6 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0184) BTB PF00651.31 VBB29931.1 - 1.4e-13 51.0 0.1 1.5e-12 47.7 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain WH1 PF00568.23 VBB29932.1 - 9.4e-25 86.7 0.0 1.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 VBB29932.1 - 1.1e-08 35.3 0.0 3.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 VBB29932.1 - 7.2e-08 32.0 0.5 0.0023 17.7 0.2 2.5 2 0 0 2 2 2 2 WH2 motif VHS PF00790.19 VBB29933.1 - 4.2e-41 140.1 0.2 4.2e-41 140.1 0.2 2.3 2 0 0 2 2 2 1 VHS domain Hrs_helical PF12210.8 VBB29933.1 - 1.3e-33 115.4 9.8 1.3e-33 115.4 9.8 2.8 1 1 1 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 VBB29933.1 - 9.9e-18 64.0 8.4 3.2e-17 62.4 8.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger Jiv90 PF14901.6 VBB29933.1 - 0.54 10.4 4.1 0.2 11.9 0.6 2.2 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone PknG_rubred PF16919.5 VBB29933.1 - 4.9 7.3 7.4 0.35 11.0 0.8 2.6 2 1 0 2 2 2 0 Protein kinase G rubredoxin domain DZR PF12773.7 VBB29933.1 - 7.5 6.7 10.5 4.4e+02 1.0 10.5 2.7 1 1 0 1 1 1 0 Double zinc ribbon Glyco_hydro_15 PF00723.21 VBB29934.1 - 1.3e-12 47.2 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase_Tyr PF07714.17 VBB29935.1 - 2.3e-85 286.0 0.0 3.3e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB29935.1 - 6e-44 150.4 0.0 9.9e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.10 VBB29935.1 - 5.2e-12 45.6 0.1 1.3e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 GTPase binding Kinase-like PF14531.6 VBB29935.1 - 0.05 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Lactamase_B PF00753.27 VBB29936.1 - 5.4e-16 59.2 0.1 1.5e-14 54.4 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB29936.1 - 9.9e-05 21.9 0.1 0.00016 21.3 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 VBB29936.1 - 0.015 14.8 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 VBB29936.1 - 0.031 14.2 0.1 0.044 13.7 0.1 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MRP-S35 PF10246.9 VBB29937.1 - 2.7e-39 133.4 0.1 4.1e-39 132.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PFK PF00365.20 VBB29938.1 - 1.3e-193 641.6 2.9 3.8e-104 348.0 0.7 2.5 2 1 0 2 2 2 2 Phosphofructokinase PGK PF00162.19 VBB29939.1 - 8.8e-82 275.0 0.2 1.1e-81 274.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 VBB29939.1 - 0.0027 17.7 0.0 0.028 14.5 0.0 2.4 2 1 1 3 3 3 1 PA domain Ribonucleas_3_3 PF14622.6 VBB29940.1 - 1.1e-37 129.1 0.1 3.6e-22 78.9 0.0 4.1 3 1 0 3 3 3 3 Ribonuclease-III-like Ribonuclease_3 PF00636.26 VBB29940.1 - 2e-37 128.0 0.1 1.1e-18 67.7 0.1 3.3 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 VBB29940.1 - 1e-08 35.8 0.0 2.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif STPPase_N PF16891.5 VBB29942.1 - 0.00038 20.8 0.3 0.00066 20.1 0.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 VBB29942.1 - 0.0017 18.9 0.1 0.015 15.8 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Dehydratase_SU PF02287.15 VBB29943.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Dehydratase small subunit MNE1 PF13762.6 VBB29943.1 - 0.12 12.4 1.5 9.5 6.2 0.1 2.8 1 1 2 3 3 3 0 Mitochondrial splicing apparatus component ubiquitin PF00240.23 VBB29945.1 - 1.2e-12 47.4 0.8 2.5e-12 46.3 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 VBB29945.1 - 0.00065 19.5 0.1 0.00099 18.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PrmA PF06325.13 VBB29946.1 - 6.4e-08 32.3 1.0 8.8e-08 31.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 VBB29946.1 - 1.7e-05 25.4 0.3 0.00054 20.6 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 VBB29946.1 - 3.4e-05 23.4 0.3 0.0025 17.4 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.20 VBB29946.1 - 0.00014 21.1 0.1 0.024 13.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 VBB29946.1 - 0.00052 19.7 0.1 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 VBB29946.1 - 0.0019 18.2 0.1 0.0039 17.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB29946.1 - 0.0041 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 VBB29946.1 - 0.0043 17.0 0.1 0.0076 16.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB29946.1 - 0.037 14.7 0.1 0.14 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 VBB29946.1 - 0.093 12.5 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 VBB29946.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_20 PF12147.8 VBB29946.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ank_5 PF13857.6 VBB29947.1 - 3.1e-15 56.1 0.4 1.4e-06 28.4 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB29947.1 - 5.8e-14 52.4 0.0 2.9e-10 40.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB29947.1 - 1.6e-11 44.5 0.2 0.00088 19.8 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB29947.1 - 1.8e-06 27.8 0.1 0.12 13.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.18 VBB29947.1 - 6e-06 26.2 16.2 1.2e-05 25.3 16.2 1.5 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 VBB29947.1 - 9.5e-05 22.7 0.2 1.3 9.6 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat cwf18 PF08315.12 VBB29948.1 - 2.1e-31 109.4 11.5 2.8e-31 109.0 11.5 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.16 VBB29948.1 - 0.12 12.9 0.2 0.25 12.0 0.2 1.4 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain SIR4_SID PF16991.5 VBB29948.1 - 0.33 11.0 4.8 0.98 9.5 4.8 1.8 1 1 0 1 1 1 0 Sir4 SID domain DUF5383 PF17355.2 VBB29948.1 - 0.73 10.2 5.3 1.2 9.6 5.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Ribosomal_L22 PF00237.19 VBB29949.1 - 1.8e-15 57.0 0.8 2.7e-15 56.5 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Exo_endo_phos PF03372.23 VBB29950.1 - 3e-20 72.8 0.0 3.6e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fig1 PF12351.8 VBB29950.1 - 0.027 14.4 0.7 0.044 13.7 0.7 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 RestrictionMunI PF11407.8 VBB29950.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI zf-H2C2_2 PF13465.6 VBB29951.1 - 0.00013 22.2 4.5 0.00013 22.2 4.5 5.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2HE PF16278.5 VBB29951.1 - 0.00026 21.4 0.6 0.00026 21.4 0.6 4.9 4 1 2 6 6 6 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 VBB29951.1 - 0.00067 20.0 57.7 0.032 14.7 0.3 7.6 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB29951.1 - 0.0041 17.8 43.8 0.12 13.3 1.9 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 VBB29951.1 - 0.048 13.3 0.7 0.048 13.3 0.7 3.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 VBB29951.1 - 0.052 14.2 0.3 0.052 14.2 0.3 3.9 5 0 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 VBB29951.1 - 7.7 7.1 10.3 20 5.8 0.0 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain NMD3 PF04981.13 VBB29953.1 - 2.3e-32 112.4 1.2 3.9e-32 111.7 1.2 1.4 1 0 0 1 1 1 1 NMD3 family Ank_2 PF12796.7 VBB29954.1 - 2.3e-44 149.9 10.0 1.8e-12 47.6 0.2 6.3 4 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB29954.1 - 1.9e-35 116.8 10.4 1.4e-05 25.1 0.1 10.1 9 0 0 9 9 9 7 Ankyrin repeat Pkinase PF00069.25 VBB29954.1 - 1.8e-34 119.3 0.0 2.4e-33 115.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29954.1 - 2e-33 115.8 0.0 8.3e-30 103.9 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_4 PF13637.6 VBB29954.1 - 6.4e-31 106.3 7.9 6.9e-06 26.5 0.0 7.1 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB29954.1 - 1.5e-27 95.3 15.3 4.4e-05 23.7 0.0 9.7 8 2 3 11 11 10 6 Ankyrin repeats (many copies) Ank PF00023.30 VBB29954.1 - 1.3e-26 91.8 17.1 6.7e-06 26.3 0.2 8.7 8 0 0 8 8 8 4 Ankyrin repeat LRR_8 PF13855.6 VBB29954.1 - 7.6e-25 86.5 29.0 6e-08 32.3 4.2 5.7 5 0 0 5 5 5 4 Leucine rich repeat Roc PF08477.13 VBB29954.1 - 1.3e-20 73.8 0.3 5.5e-17 62.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 VBB29954.1 - 1.9e-19 69.5 35.7 3.6e-06 27.2 0.6 7.7 7 0 0 7 7 7 5 Leucine Rich repeats (2 copies) COR PF16095.5 VBB29954.1 - 2.3e-19 70.0 0.0 1.6e-17 64.0 0.0 2.3 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Ras PF00071.22 VBB29954.1 - 7e-07 29.0 0.1 0.00013 21.6 0.0 2.8 3 0 0 3 3 3 1 Ras family LRR_6 PF13516.6 VBB29954.1 - 6.6e-05 22.7 16.5 0.67 10.2 0.2 8.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 VBB29954.1 - 0.00015 21.8 22.6 13 6.8 0.0 9.9 8 2 0 8 8 8 0 Leucine Rich Repeat AAA_16 PF13191.6 VBB29954.1 - 0.0099 16.3 2.1 0.35 11.2 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain Myotub-related PF06602.14 VBB29955.1 - 3.6e-50 170.9 0.7 7e-50 169.9 0.0 1.7 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Bax1-I PF01027.20 VBB29955.1 - 3.6e-23 82.5 16.1 1.7e-14 54.1 9.8 2.2 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 GRAM PF02893.20 VBB29955.1 - 7.9e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain LSM PF01423.22 VBB29955.1 - 1.9e-05 24.3 0.0 4.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 LSM domain E2F_TDP PF02319.20 VBB29956.1 - 4.5e-14 52.3 0.2 1.4e-13 50.7 0.2 1.9 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 VBB29956.1 - 0.037 13.9 0.1 0.086 12.7 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rhodanese_C PF12368.8 VBB29956.1 - 1.4 9.3 3.8 0.67 10.4 0.2 2.2 3 0 0 3 3 3 0 Rhodanase C-terminal LIM PF00412.22 VBB29959.1 - 4.3e-06 26.9 5.9 9.7e-06 25.7 5.9 1.6 1 0 0 1 1 1 1 LIM domain Transglut_core PF01841.19 VBB29959.1 - 0.02 15.4 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily FbpA PF05833.11 VBB29959.1 - 0.13 11.0 8.5 0.2 10.4 8.5 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF3037 PF11236.8 VBB29959.1 - 1.7 9.1 4.9 5.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Pro_isomerase PF00160.21 VBB29960.1 - 4.5e-41 140.8 0.0 1.1e-40 139.5 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_1e PF01406.19 VBB29961.1 - 6e-123 410.0 0.9 1.2e-122 409.0 0.9 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain TIM PF00121.18 VBB29961.1 - 7.1e-85 284.3 0.1 1.4e-84 283.3 0.1 1.5 1 0 0 1 1 1 1 Triosephosphate isomerase tRNA-synt_1g PF09334.11 VBB29961.1 - 2e-05 23.5 0.3 0.012 14.4 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 VBB29961.1 - 0.0077 15.2 0.0 0.0077 15.2 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain DNTTIP1_dimer PF18192.1 VBB29961.1 - 0.21 11.9 1.0 8.4 6.8 0.0 3.1 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain Motile_Sperm PF00635.26 VBB29962.1 - 1.5e-06 28.0 0.0 1.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2362 PF10154.9 VBB29964.1 - 2.6e-108 363.2 1.3 3e-108 363.0 1.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) TetR_C_24 PF17932.1 VBB29964.1 - 0.055 13.7 0.7 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lipoprotein_9 PF03180.14 VBB29964.1 - 0.065 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 NLPA lipoprotein DUF507 PF04368.13 VBB29964.1 - 0.86 9.5 5.3 0.58 10.1 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF507) TIP120 PF08623.10 VBB29965.1 - 4.4e-61 205.5 16.2 8.7e-61 204.6 1.2 6.1 6 1 1 7 7 7 1 TATA-binding protein interacting (TIP20) Hydrolase_4 PF12146.8 VBB29965.1 - 8.4e-17 61.2 0.0 6.3e-13 48.5 0.0 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 HEAT_2 PF13646.6 VBB29965.1 - 2.4e-15 56.7 8.6 0.011 16.1 0.0 8.5 7 2 2 9 9 9 3 HEAT repeats Abhydrolase_1 PF00561.20 VBB29965.1 - 9.8e-14 51.6 0.1 2.5e-09 37.2 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold HEAT PF02985.22 VBB29965.1 - 3.2e-12 45.6 20.6 0.4 11.1 0.1 12.6 12 0 0 12 12 12 2 HEAT repeat Abhydrolase_6 PF12697.7 VBB29965.1 - 4.1e-09 37.4 0.0 9.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family HEAT_EZ PF13513.6 VBB29965.1 - 8.2e-08 32.6 9.5 5.5 7.6 0.0 9.7 11 0 0 11 11 9 2 HEAT-like repeat Abhydrolase_3 PF07859.13 VBB29965.1 - 1.4e-06 28.3 0.0 5.6e-06 26.4 0.0 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold Cnd1 PF12717.7 VBB29965.1 - 8.8e-06 25.8 20.4 0.00011 22.2 0.1 6.4 5 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 VBB29965.1 - 0.00051 20.0 9.4 0.0026 17.7 0.6 4.9 2 1 0 3 3 3 1 Domain of unknown function (DUF3385) ParcG PF10274.9 VBB29965.1 - 0.0015 18.7 18.7 0.062 13.4 0.1 6.5 7 1 1 8 8 8 1 Parkin co-regulated protein Abhydrolase_2 PF02230.16 VBB29965.1 - 0.0086 15.9 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase MMS19_N PF14500.6 VBB29965.1 - 0.01 15.5 0.4 0.01 15.5 0.4 6.2 7 2 0 9 9 9 1 Dos2-interacting transcription regulator of RNA-Pol-II DLH PF01738.18 VBB29965.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 VBB29965.1 - 0.026 14.4 0.0 0.093 12.6 0.0 2.0 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 VBB29965.1 - 0.05 13.1 0.1 1.3 8.6 0.0 3.2 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase Telomere_reg-2 PF10193.9 VBB29965.1 - 0.095 13.2 12.9 2 8.9 0.0 6.2 8 0 0 8 8 7 0 Telomere length regulation protein LIP PF03583.14 VBB29965.1 - 0.12 11.6 0.0 8.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Secretory lipase DUF4042 PF13251.6 VBB29965.1 - 0.29 10.8 10.0 0.065 12.9 2.6 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 VBB29965.1 - 0.74 10.0 5.5 98 3.2 0.1 5.1 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 VBB29965.1 - 2.8 8.1 8.8 1 9.5 0.5 4.5 5 1 1 6 6 4 0 V-ATPase subunit H Spermine_synth PF01564.17 VBB29966.1 - 7.5e-08 32.0 3.1 1e-07 31.6 1.7 1.9 1 1 0 2 2 2 1 Spermine/spermidine synthase domain PCMT PF01135.19 VBB29966.1 - 2.2e-05 24.3 0.0 5.8e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 VBB29966.1 - 7.8e-05 23.3 0.0 0.00018 22.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 VBB29966.1 - 0.00035 20.3 0.3 0.00055 19.6 0.3 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 VBB29966.1 - 0.0051 16.7 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB29966.1 - 0.011 15.6 0.4 0.016 15.0 0.4 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 VBB29966.1 - 0.013 14.7 0.2 0.023 13.9 0.2 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.12 VBB29966.1 - 0.018 15.8 0.1 0.11 13.3 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain LRR_5 PF13306.6 VBB29966.1 - 0.064 13.2 4.0 0.2 11.6 4.0 1.9 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF4945 PF16303.5 VBB29966.1 - 0.072 13.0 0.1 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Ribosomal_S18 PF01084.20 VBB29967.1 - 0.00011 22.4 0.8 0.00017 21.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S18 PRP1_N PF06424.12 VBB29968.1 - 3.6e-56 189.7 7.4 3.6e-56 189.7 7.4 2.6 3 0 0 3 3 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 VBB29968.1 - 4.4e-30 101.8 29.9 0.00057 20.5 0.1 14.0 4 2 10 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 VBB29968.1 - 2.9e-15 56.5 16.3 7e-06 26.5 0.1 9.4 7 3 4 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB29968.1 - 3.4e-11 42.7 0.1 3.9 8.1 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB29968.1 - 3.8e-09 36.0 28.0 0.0024 17.9 0.0 10.2 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB29968.1 - 4.9e-08 33.5 13.8 0.13 12.9 0.0 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB29968.1 - 1.6e-07 30.8 9.3 0.011 15.6 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB29968.1 - 8.9e-05 22.4 18.5 0.39 11.1 0.1 8.2 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB29968.1 - 0.00029 20.9 1.2 0.67 10.1 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.9 VBB29968.1 - 0.00033 19.5 1.5 0.24 10.1 0.1 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3808) TPR_11 PF13414.6 VBB29968.1 - 0.0056 16.3 3.7 30 4.4 1.7 5.6 6 0 0 6 6 6 0 TPR repeat ANAPC3 PF12895.7 VBB29968.1 - 0.011 16.0 5.6 39 4.6 0.2 6.0 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 VBB29968.1 - 0.012 15.6 0.4 5.6 7.1 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Suf PF05843.14 VBB29968.1 - 0.018 15.1 7.2 5.2 7.0 0.1 4.2 4 1 1 5 5 4 0 Suppressor of forked protein (Suf) Mt_ATP_synt PF15704.5 VBB29968.1 - 0.019 14.9 0.6 0.19 11.6 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase subunit TPR_12 PF13424.6 VBB29968.1 - 0.021 15.1 20.9 0.26 11.6 0.0 7.2 7 2 1 8 8 7 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 VBB29968.1 - 0.022 14.7 2.4 3 7.7 0.1 3.4 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF2031 PF09592.10 VBB29968.1 - 0.036 13.6 1.1 0.12 11.9 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF4300 PF14133.6 VBB29968.1 - 0.036 13.8 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) ChAPs PF09295.10 VBB29968.1 - 0.058 12.4 3.7 0.13 11.3 0.0 3.0 3 2 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF410 PF04190.13 VBB29968.1 - 0.064 13.0 0.4 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF410) Fungal_TACC PF12709.7 VBB29968.1 - 0.22 12.0 5.6 0.46 11.0 1.5 2.9 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_6 PF13174.6 VBB29968.1 - 0.54 11.0 20.4 17 6.3 0.0 8.6 11 0 0 11 11 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 VBB29968.1 - 0.84 9.7 3.6 5 7.2 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AC_N PF16214.5 VBB29969.1 - 0.0066 15.6 0.1 0.0096 15.1 0.1 1.1 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF4446 PF14584.6 VBB29969.1 - 0.045 13.7 0.8 0.098 12.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SUR7 PF06687.12 VBB29969.1 - 0.081 12.5 1.7 0.12 12.0 1.7 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF5591 PF17884.1 VBB29969.1 - 0.17 11.7 0.8 2.5 7.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5591) CactinC_cactus PF09732.9 VBB29970.1 - 1.5e-55 186.5 7.9 3.8e-55 185.2 7.9 1.7 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 VBB29970.1 - 1.4e-48 165.3 2.8 1.4e-48 165.3 2.8 2.9 4 1 0 4 4 4 1 Conserved mid region of cactin PI3_PI4_kinase PF00454.27 VBB29971.1 - 2.3e-36 125.9 0.0 3.6e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase VWA PF00092.28 VBB29972.1 - 5.8e-59 199.3 2.7 6.5e-30 104.7 0.4 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 VBB29972.1 - 1.5e-30 106.0 0.2 6.5e-15 55.7 0.0 3.2 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 VBB29972.1 - 0.00017 21.0 0.2 0.074 12.4 0.0 3.3 3 1 0 3 3 3 2 VWA domain containing CoxE-like protein JHD PF17811.1 VBB29973.1 - 1.3e-06 28.9 0.1 1.3e-06 28.9 0.1 2.5 3 0 0 3 3 3 1 Jumonji helical domain Cupin_8 PF13621.6 VBB29973.1 - 5.3e-06 26.3 0.4 7.1e-05 22.6 0.0 2.9 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 VBB29973.1 - 2.5e-05 24.7 4.0 0.00012 22.4 0.5 3.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase fn3 PF00041.21 VBB29974.1 - 5.9e-42 141.9 0.2 4.9e-12 46.0 0.0 4.8 4 0 0 4 4 4 4 Fibronectin type III domain Arm PF00514.23 VBB29974.1 - 1.1e-26 92.0 12.7 2.1e-07 30.8 0.0 6.0 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat Pur_ac_phosph_N PF16656.5 VBB29974.1 - 1.3e-05 25.6 0.5 1.9 9.1 0.0 5.4 5 0 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain HEAT_EZ PF13513.6 VBB29974.1 - 0.001 19.5 1.2 1.9 9.1 0.0 3.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 VBB29974.1 - 0.0063 16.9 0.5 3.4 8.1 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 VBB29974.1 - 0.0066 16.6 1.1 7.7 7.1 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat Atx10homo_assoc PF09759.9 VBB29974.1 - 0.098 12.7 0.7 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain TAF4 PF05236.14 VBB29974.1 - 2.9 7.6 5.8 0.2 11.4 0.6 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family ThiF PF00899.21 VBB29976.1 - 5.1e-36 124.3 0.2 4.5e-24 85.1 0.1 2.1 1 1 1 2 2 2 2 ThiF family Rhodanese PF00581.20 VBB29976.1 - 2.8e-11 43.9 0.0 7.6e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain CMV_1a_C PF12503.8 VBB29976.1 - 0.0019 18.2 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein C terminal DAO PF01266.24 VBB29976.1 - 0.068 12.7 0.1 0.19 11.2 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mucin PF01456.17 VBB29977.1 - 3.6 7.6 31.1 6.7 6.7 31.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein AMPK1_CBM PF16561.5 VBB29978.1 - 2.4e-10 40.5 0.3 1.1e-09 38.4 0.0 2.3 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase DUF745 PF05335.13 VBB29978.1 - 0.057 13.1 138.8 0.011 15.4 3.2 14.9 8 3 8 16 16 16 0 Protein of unknown function (DUF745) Calpain_inhib PF00748.19 VBB29979.1 - 1.8 9.1 5.6 0.13 12.7 0.8 1.6 2 0 0 2 2 2 0 Calpain inhibitor PI3_PI4_kinase PF00454.27 VBB29980.1 - 1.2e-48 166.2 0.5 2.6e-47 161.8 0.5 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 VBB29980.1 - 1.4e-30 106.1 2.4 2.9e-30 105.0 2.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX PF00787.24 VBB29980.1 - 1.4e-12 47.6 0.3 6.5e-12 45.4 0.4 2.1 2 0 0 2 2 2 1 PX domain C2 PF00168.30 VBB29980.1 - 2.8e-12 46.8 0.0 6.3e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain PI3K_C2 PF00792.24 VBB29980.1 - 6e-07 29.5 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 VBB29980.1 - 9.1e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 VBB29980.1 - 0.00051 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Cbl_N PF02262.16 VBB29981.1 - 8.4e-48 161.5 1.1 1.3e-47 160.9 1.1 1.3 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 VBB29981.1 - 1.3e-45 153.2 0.0 2.6e-45 152.2 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 VBB29981.1 - 1.4e-35 121.8 3.4 3.1e-35 120.8 3.4 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 VBB29981.1 - 3.3e-13 49.3 8.7 6e-13 48.4 8.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 VBB29981.1 - 2.3e-11 43.4 7.3 3.6e-11 42.7 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB29981.1 - 7.6e-09 35.3 7.0 1.4e-08 34.5 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB29981.1 - 2.8e-07 30.7 7.1 5.1e-07 29.9 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 VBB29981.1 - 1e-06 28.7 5.3 2.1e-06 27.6 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB29981.1 - 1.4e-05 24.9 7.6 2.9e-05 23.8 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB29981.1 - 0.0037 17.2 10.1 0.0083 16.1 10.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 VBB29981.1 - 0.026 14.8 6.7 0.051 13.9 6.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 VBB29981.1 - 0.039 14.1 7.8 0.077 13.2 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 VBB29981.1 - 0.23 11.6 4.9 0.6 10.3 4.9 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 VBB29981.1 - 1 9.0 6.5 1.9 8.2 6.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Claudin_2 PF13903.6 VBB29982.1 - 4.7e-05 23.2 6.7 9.8e-05 22.2 6.7 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SLATT_3 PF18184.1 VBB29982.1 - 0.0024 18.0 0.3 0.0024 18.0 0.3 1.6 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain 3 Trp_oprn_chp PF09534.10 VBB29982.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Arteri_Gl PF00951.18 VBB29982.1 - 2.1 8.1 8.3 0.78 9.5 5.9 1.5 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF2569 PF10754.9 VBB29982.1 - 9.3 6.7 11.0 7.2 7.0 7.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) AbiJ_NTD3 PF18860.1 VBB29984.1 - 0.0063 16.1 0.7 0.013 15.0 0.7 1.5 1 0 0 1 1 1 1 AbiJ N-terminal domain 3 Methyltransf_4 PF02390.17 VBB29984.1 - 0.012 15.0 0.1 0.049 13.1 0.1 2.0 1 0 0 1 1 1 0 Putative methyltransferase DUF4428 PF14471.6 VBB29984.1 - 0.7 9.9 6.4 3.4 7.6 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Linker_histone PF00538.19 VBB29985.1 - 6.7e-26 90.5 0.1 6.7e-26 90.5 0.1 2.2 3 0 0 3 3 3 1 linker histone H1 and H5 family DUF2205 PF10224.9 VBB29986.1 - 8e-26 89.8 0.5 1e-25 89.5 0.5 1.1 1 0 0 1 1 1 1 Short coiled-coil protein KASH_CCD PF14662.6 VBB29986.1 - 0.0023 17.8 1.9 0.003 17.4 1.9 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FliT PF05400.13 VBB29986.1 - 0.003 18.3 0.8 0.0046 17.7 0.8 1.3 1 0 0 1 1 1 1 Flagellar protein FliT CENP-H PF05837.12 VBB29986.1 - 0.0032 17.9 0.8 0.0043 17.5 0.8 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) TACC_C PF05010.14 VBB29986.1 - 0.01 15.7 0.5 0.013 15.3 0.5 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0242 PF06785.11 VBB29986.1 - 0.013 15.6 0.3 0.013 15.6 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sas10_Utp3 PF04000.15 VBB29986.1 - 0.022 15.4 0.3 0.035 14.7 0.3 1.3 1 0 0 1 1 1 0 Sas10/Utp3/C1D family YabA PF06156.13 VBB29986.1 - 0.025 15.2 0.4 0.03 15.0 0.4 1.2 1 0 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 VBB29986.1 - 0.047 14.1 1.7 0.072 13.5 1.7 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HalX PF08663.10 VBB29986.1 - 0.067 13.5 2.5 0.067 13.5 2.5 1.5 2 0 0 2 2 2 0 HalX domain HALZ PF02183.18 VBB29986.1 - 0.11 12.8 5.7 2.1 8.6 1.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 VBB29986.1 - 0.16 12.1 1.6 0.24 11.5 1.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor UNC-50 PF05216.13 VBB29987.1 - 7.6e-71 238.2 21.0 8.8e-71 238.0 21.0 1.1 1 0 0 1 1 1 1 UNC-50 family Neur_chan_memb PF02932.16 VBB29988.1 - 5.6e-33 115.0 1.6 1e-32 114.1 1.6 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3181 PF11378.8 VBB29988.1 - 0.036 14.4 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Neur_chan_LBD PF02931.23 VBB29989.1 - 1.1e-41 142.6 0.4 1.6e-41 142.2 0.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB29989.1 - 8.8e-19 68.5 0.0 1.4e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Itfg2 PF15907.5 VBB29990.1 - 9.2e-14 51.2 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 FBA PF04300.13 VBB29991.1 - 7.8e-51 172.3 0.0 4.1e-28 98.3 0.0 2.2 1 1 1 2 2 2 2 F-box associated region Yip1 PF04893.17 VBB29991.1 - 6.4e-10 39.0 3.5 1.1e-09 38.3 3.5 1.3 1 0 0 1 1 1 1 Yip1 domain F-box-like PF12937.7 VBB29991.1 - 9.2e-05 22.3 0.3 0.00039 20.3 0.3 2.1 1 0 0 1 1 1 1 F-box-like OxoGdeHyase_C PF16870.5 VBB29991.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal F-box_5 PF18511.1 VBB29991.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 F-box Nop PF01798.18 VBB29992.1 - 1e-67 228.0 0.0 1.6e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 VBB29992.1 - 9.4e-40 136.3 4.4 1.8e-39 135.4 4.4 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Perilipin PF03036.16 VBB29992.1 - 0.072 12.1 0.9 0.15 11.1 0.0 2.0 3 0 0 3 3 3 0 Perilipin family WD40 PF00400.32 VBB29993.1 - 2.3e-07 31.4 3.6 0.068 14.1 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB29993.1 - 0.0025 18.1 0.0 0.3 11.4 0.0 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BORA_N PF15280.6 VBB29994.1 - 7.3e-46 156.7 6.2 7.3e-46 156.7 6.2 1.5 2 0 0 2 2 2 1 Protein aurora borealis N-terminus PX PF00787.24 VBB29995.1 - 1.3e-19 70.3 0.9 1.3e-18 67.0 0.2 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 VBB29995.1 - 4.2e-16 59.2 8.7 6.9e-14 52.0 7.0 2.6 1 1 0 1 1 1 1 Vps5 C terminal like SUIM_assoc PF16619.5 VBB29995.1 - 0.15 12.1 11.2 0.069 13.2 8.3 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FlxA PF14282.6 VBB29995.1 - 1 9.4 22.3 3.7 7.6 0.4 2.7 2 0 0 2 2 2 0 FlxA-like protein SMAP PF15477.6 VBB29995.1 - 8.5 7.4 10.3 17 6.5 0.0 2.9 2 1 0 2 2 2 0 Small acidic protein family GLTT PF01744.20 VBB29996.1 - 0.06 13.1 4.5 0.06 13.1 4.5 2.6 2 1 0 2 2 2 0 GLTT repeat (6 copies) Claudin_2 PF13903.6 VBB29996.1 - 5 6.8 10.8 6.9 6.4 10.8 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.25 VBB29997.1 - 1.4e-39 136.0 0.0 1.7e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB29997.1 - 5.9e-21 74.9 0.0 7.2e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB29997.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_transf_25 PF01755.17 VBB29998.1 - 2.3e-28 99.4 0.2 1.5e-26 93.5 0.0 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Anp1 PF03452.14 VBB29998.1 - 3.4e-05 23.4 0.1 0.019 14.4 0.2 2.2 1 1 1 2 2 2 2 Anp1 Cullin PF00888.22 VBB29999.1 - 4.1e-182 607.0 15.4 6.1e-182 606.5 15.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 VBB29999.1 - 2.2e-13 50.0 0.5 8.9e-13 48.1 0.5 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 VBB29999.1 - 0.018 15.4 0.1 0.084 13.3 0.1 2.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC MarR PF01047.22 VBB29999.1 - 0.045 13.7 0.6 0.76 9.8 0.0 2.7 2 0 0 2 2 2 0 MarR family Mating_N PF12731.7 VBB29999.1 - 0.12 12.5 1.1 1.2 9.3 0.1 3.1 2 1 1 3 3 3 0 Mating-type protein beta 1 zf-Di19 PF05605.12 VBB30000.1 - 7e-05 23.0 6.5 7e-05 23.0 6.5 2.8 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-CCCH_2 PF14608.6 VBB30000.1 - 0.0019 18.6 9.5 0.0019 18.6 9.5 2.9 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-C2H2 PF00096.26 VBB30000.1 - 0.0022 18.3 11.8 0.26 11.8 0.8 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB30000.1 - 0.015 16.1 4.3 0.015 16.1 4.3 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 VBB30000.1 - 0.037 14.1 14.5 0.038 14.1 10.8 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 VBB30000.1 - 0.29 11.2 8.6 4 7.6 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 VBB30000.1 - 0.41 10.5 4.9 1.1 9.1 0.7 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Macoilin PF09726.9 VBB30000.1 - 4.8 5.6 20.2 6.4 5.2 20.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF936 PF06075.12 VBB30000.1 - 5.3 5.8 29.7 8 5.2 29.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Tetraspanin PF00335.20 VBB30001.1 - 2.1e-10 40.7 4.5 2.5e-10 40.5 4.5 1.1 1 0 0 1 1 1 1 Tetraspanin family Neurensin PF14927.6 VBB30001.1 - 0.0043 16.8 0.4 0.037 13.7 0.0 1.9 1 1 1 2 2 2 1 Neurensin DUF2207 PF09972.9 VBB30001.1 - 0.16 10.7 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 VBB30002.1 - 4.1e-56 190.3 0.0 5.2e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30002.1 - 1.8e-41 142.2 0.0 2.4e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB30002.1 - 8.8e-08 31.8 0.2 2.1e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 VBB30002.1 - 0.0056 15.8 0.1 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 VBB30002.1 - 0.029 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB30002.1 - 0.13 11.0 0.0 0.32 9.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 VBB30002.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HAGH_C PF16123.5 VBB30004.1 - 6.3e-20 71.5 0.3 1.1e-19 70.7 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 VBB30004.1 - 1.6e-10 41.3 6.1 2.6e-09 37.4 6.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Stathmin PF00836.19 VBB30004.1 - 0.017 15.1 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Stathmin family Lactamase_B_3 PF13483.6 VBB30004.1 - 0.022 14.7 0.2 0.043 13.7 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain UvrA_DNA-bind PF17755.1 VBB30004.1 - 0.031 14.6 0.0 0.07 13.5 0.0 1.6 2 0 0 2 2 2 0 UvrA DNA-binding domain BcrAD_BadFG PF01869.20 VBB30004.1 - 0.062 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B_2 PF12706.7 VBB30004.1 - 0.3 10.6 3.4 4.9 6.6 3.4 2.2 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Palm_thioest PF02089.15 VBB30005.1 - 6.2e-77 258.7 0.0 9.3e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase HSP70 PF00012.20 VBB30007.1 - 2.5e-254 845.0 21.6 1.8e-252 838.9 21.6 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 VBB30007.1 - 2.3e-15 56.2 2.8 8.2e-13 47.9 0.4 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 VBB30007.1 - 3.1e-05 24.3 4.5 0.026 14.9 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 VBB30007.1 - 9.7e-05 22.2 0.2 0.00044 20.0 0.1 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF222 PF02720.17 VBB30007.1 - 0.018 14.5 1.1 0.041 13.4 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF222) Ead_Ea22 PF13935.6 VBB30007.1 - 0.039 14.6 5.4 0.31 11.7 0.0 2.7 2 0 0 2 2 2 0 Ead/Ea22-like protein Tn7_Tnp_TnsA_C PF08721.11 VBB30007.1 - 0.054 14.1 0.6 0.13 12.9 0.6 1.6 1 0 0 1 1 1 0 TnsA endonuclease C terminal TAFH PF07531.14 VBB30007.1 - 0.24 11.5 2.6 3.4 7.8 0.7 3.1 3 0 0 3 3 3 0 NHR1 homology to TAF MoeA_N PF03453.17 VBB30008.1 - 8.4e-37 126.3 1.1 1.2e-36 125.8 1.1 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 VBB30008.1 - 2.6e-25 88.8 0.0 4.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 VBB30008.1 - 2.9e-05 24.2 0.0 7.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) 7tm_1 PF00001.21 VBB30009.1 - 2.5e-06 27.0 0.8 2.5e-06 27.0 0.8 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) zf-LITAF-like PF10601.9 VBB30009.1 - 0.071 13.4 0.7 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PP2C PF00481.21 VBB30010.1 - 2.4e-29 102.7 0.1 2.9e-29 102.5 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 VBB30011.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 VBB30011.1 - 0.0066 16.1 0.0 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Band_7 PF01145.25 VBB30012.1 - 1.2e-17 64.4 2.3 1.8e-17 63.9 2.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 VBB30012.1 - 0.00064 19.5 0.1 0.00091 19.0 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family pPIWI_RE_REase PF18154.1 VBB30012.1 - 0.024 14.6 1.7 0.096 12.7 0.5 2.1 1 1 1 2 2 2 0 REase associating with pPIWI_RE DUF5405 PF17399.2 VBB30012.1 - 0.025 14.8 0.4 0.065 13.5 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5405) PGDYG PF14083.6 VBB30012.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 PGDYG protein GP68 PF17469.2 VBB30012.1 - 0.28 11.6 1.2 0.53 10.7 0.7 1.7 1 1 1 2 2 2 0 Phage protein Gp68 PhoLip_ATPase_C PF16212.5 VBB30013.1 - 1.2e-46 159.6 38.6 4e-43 148.0 23.6 3.8 3 1 1 4 4 4 2 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 VBB30013.1 - 3.1e-12 46.4 0.0 3.6e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 VBB30013.1 - 3.3e-11 43.9 0.5 0.00012 22.5 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 VBB30013.1 - 0.017 14.9 0.1 0.017 14.9 0.1 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PspA_IM30 PF04012.12 VBB30013.1 - 0.071 12.7 0.8 0.18 11.4 0.8 1.6 1 0 0 1 1 1 0 PspA/IM30 family Syja_N PF02383.18 VBB30014.1 - 2.2e-69 234.3 0.1 5.7e-69 232.9 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 VBB30014.1 - 6.4e-14 52.0 0.0 9.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1866 PF08952.11 VBB30014.1 - 2.1e-13 50.4 0.0 4.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Peptidase_A22B PF04258.13 VBB30015.1 - 5.7e-18 65.4 11.2 1.2e-17 64.4 11.2 1.5 1 1 0 1 1 1 1 Signal peptide peptidase Mid2 PF04478.12 VBB30015.1 - 3.1 7.6 6.6 60 3.4 0.4 3.4 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor FA_desaturase PF00487.24 VBB30016.1 - 1.4e-18 67.6 7.3 1.7e-18 67.4 7.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Ion_trans_2 PF07885.16 VBB30017.1 - 1.1e-22 79.7 15.3 3.4e-17 62.2 0.1 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB30017.1 - 0.00081 18.7 0.2 0.00081 18.7 0.2 2.4 2 0 0 2 2 2 1 Ion transport protein TF_AP-2 PF03299.14 VBB30020.1 - 3.8e-10 40.0 0.1 5.5e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Transcription factor AP-2 BACK PF07707.15 VBB30021.1 - 2.4e-06 27.6 0.0 4.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF2102 PF09875.9 VBB30021.1 - 0.072 12.8 0.4 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) BTB PF00651.31 VBB30022.1 - 3.4e-12 46.6 5.8 5.1e-06 26.7 0.3 3.2 3 0 0 3 3 3 2 BTB/POZ domain DUF1265 PF06887.14 VBB30022.1 - 0.025 14.5 0.3 0.056 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) RNA_pol_Rpb5_C PF01191.19 VBB30023.1 - 2.4e-35 120.2 0.8 3.7e-35 119.6 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 VBB30023.1 - 5.4e-23 81.4 0.2 1.1e-22 80.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF4817 PF16087.5 VBB30023.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) AAA PF00004.29 VBB30024.1 - 5e-28 98.2 0.0 7.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB30024.1 - 1.7e-08 34.9 0.0 4.2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB30024.1 - 2.9e-06 27.8 0.0 8.1e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 VBB30024.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB30024.1 - 2e-05 25.1 0.0 4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 VBB30024.1 - 2.6e-05 24.3 0.0 5.7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 VBB30024.1 - 0.00017 21.9 0.0 0.00042 20.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 VBB30024.1 - 0.00025 21.2 0.0 0.0006 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 VBB30024.1 - 0.00031 20.7 0.0 0.00057 19.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytidylate_kin PF02224.18 VBB30024.1 - 0.00034 20.4 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_19 PF13245.6 VBB30024.1 - 0.00037 20.8 0.1 0.0085 16.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 VBB30024.1 - 0.0004 20.2 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 VBB30024.1 - 0.00059 19.6 0.0 0.0037 17.0 0.0 2.1 1 1 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 VBB30024.1 - 0.00069 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 VBB30024.1 - 0.00078 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 VBB30024.1 - 0.0016 17.7 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 VBB30024.1 - 0.0019 17.8 0.5 0.18 11.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 VBB30024.1 - 0.0025 18.1 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 VBB30024.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 VBB30024.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 VBB30024.1 - 0.0036 17.0 0.0 0.0063 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 VBB30024.1 - 0.0052 16.8 0.3 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 VBB30024.1 - 0.0095 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_7 PF12775.7 VBB30024.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 VBB30024.1 - 0.018 14.3 0.0 4.9 6.3 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 VBB30024.1 - 0.018 14.2 0.1 0.044 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ECH_1 PF00378.20 VBB30024.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase AAA_3 PF07726.11 VBB30024.1 - 0.019 14.8 0.1 0.052 13.4 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 VBB30024.1 - 0.021 14.2 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 VBB30024.1 - 0.027 14.4 0.1 0.28 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Zot PF05707.12 VBB30024.1 - 0.037 13.7 0.0 0.082 12.5 0.0 1.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) ATPase PF06745.13 VBB30024.1 - 0.038 13.3 0.1 1.1 8.6 0.0 2.2 1 1 1 2 2 2 0 KaiC PduV-EutP PF10662.9 VBB30024.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 VBB30024.1 - 0.045 14.2 0.1 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 VBB30024.1 - 0.049 12.9 0.0 0.084 12.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 VBB30024.1 - 0.066 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 VBB30024.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_6 PF12774.7 VBB30024.1 - 0.091 11.7 0.0 0.28 10.1 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 VBB30024.1 - 0.093 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 VBB30024.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.12 VBB30024.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 VBB30024.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PQ-loop PF04193.14 VBB30025.1 - 5.7e-37 125.3 11.5 1.9e-19 69.1 7.2 2.7 2 0 0 2 2 2 2 PQ loop repeat TMEM43 PF07787.12 VBB30025.1 - 1 8.7 3.0 2.1 7.7 0.5 2.2 2 0 0 2 2 2 0 Transmembrane protein 43 GET2 PF08690.10 VBB30026.1 - 2.7 7.6 4.2 0.55 9.9 0.1 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 I-set PF07679.16 VBB30027.1 - 1.9e-12 47.1 0.2 0.0038 17.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB30027.1 - 1.7e-11 44.5 0.0 0.017 15.7 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 VBB30027.1 - 5.1e-11 42.7 0.1 0.017 15.3 0.0 4.3 4 1 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.25 VBB30027.1 - 1.2e-10 41.4 0.0 5e-05 23.4 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 VBB30027.1 - 0.011 15.3 0.0 0.38 10.4 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin domain Ig_2 PF13895.6 VBB30027.1 - 0.026 14.9 0.0 2.9 8.3 0.0 3.7 5 0 0 5 5 5 0 Immunoglobulin domain Pkinase_Tyr PF07714.17 VBB30028.1 - 1.7e-87 292.9 0.0 2.4e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30028.1 - 2.1e-37 128.9 0.1 3e-26 92.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.6 VBB30028.1 - 2.2e-14 53.5 0.0 1.1e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 VBB30028.1 - 1.2e-12 48.2 0.0 9.4e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 VBB30028.1 - 3.1e-12 46.4 0.0 4.1e-05 23.6 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 VBB30028.1 - 3.1e-06 27.2 0.0 0.048 13.8 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 VBB30028.1 - 0.0032 17.7 0.8 1.1 9.6 0.0 2.9 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain LapA_dom PF06305.11 VBB30028.1 - 0.011 15.6 1.5 0.022 14.6 1.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ig_5 PF16681.5 VBB30028.1 - 0.014 15.7 1.0 1.9 9.0 0.0 3.1 4 0 0 4 4 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain APH PF01636.23 VBB30028.1 - 0.042 13.8 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4381 PF14316.6 VBB30028.1 - 0.066 13.5 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VirB8 PF04335.13 VBB30028.1 - 0.11 12.3 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 VirB8 protein Pkinase_fungal PF17667.1 VBB30028.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-RING_2 PF13639.6 VBB30029.1 - 8e-08 32.5 10.1 8e-08 32.5 10.1 3.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 VBB30029.1 - 1.2e-07 31.5 9.1 1.2e-07 31.5 9.1 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB30029.1 - 1.3e-06 28.2 9.0 1.3e-06 28.2 9.0 3.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB30029.1 - 8.9e-06 25.9 7.1 8.9e-06 25.9 7.1 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 VBB30029.1 - 2.5e-05 24.0 6.7 2.5e-05 24.0 6.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB30029.1 - 3.9e-05 23.6 4.4 3.9e-05 23.6 4.4 2.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 VBB30029.1 - 0.00048 20.0 7.1 0.00048 20.0 7.1 2.9 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 VBB30029.1 - 0.0083 16.0 7.5 0.0083 16.0 7.5 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 PHD PF00628.29 VBB30029.1 - 0.014 15.3 13.7 0.014 15.3 13.7 3.6 2 2 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.6 VBB30029.1 - 0.022 14.9 5.3 0.022 14.9 5.3 3.4 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING DUF3585 PF12130.8 VBB30030.1 - 0.0068 16.6 2.6 0.014 15.6 0.2 2.1 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain SAYSvFN PF10260.9 VBB30031.1 - 4.8e-27 93.7 1.4 4.8e-27 93.7 0.2 1.6 2 0 0 2 2 2 1 Uncharacterized conserved domain (SAYSvFN) Exotox-A_target PF09102.10 VBB30031.1 - 0.16 11.9 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A, targeting HEAT PF02985.22 VBB30032.1 - 1.4e-09 37.4 24.9 0.0026 17.9 0.4 10.2 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 VBB30032.1 - 2.3e-08 34.3 4.1 0.029 14.8 0.4 7.1 5 2 1 6 6 6 2 HEAT repeats DRIM PF07539.12 VBB30032.1 - 0.001 17.5 0.0 0.016 13.5 0.0 2.9 2 1 0 2 2 2 1 Down-regulated in metastasis Cnd1 PF12717.7 VBB30032.1 - 0.0021 18.1 1.9 12 6.0 0.4 4.7 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 VBB30032.1 - 0.0045 17.5 20.0 0.36 11.4 0.1 9.5 10 0 0 10 10 10 1 HEAT-like repeat Cnd3 PF12719.7 VBB30032.1 - 0.041 13.1 3.3 1.6 7.8 0.1 4.3 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 VBB30032.1 - 0.042 13.4 0.1 0.042 13.4 0.1 4.8 4 1 1 5 5 5 0 CLASP N terminal Adaptin_N PF01602.20 VBB30032.1 - 0.18 10.3 14.8 0.51 8.8 0.0 4.5 5 0 0 5 5 5 0 Adaptin N terminal region Condensin2nSMC PF12422.8 VBB30032.1 - 0.18 12.0 4.7 3.6 7.7 0.0 3.6 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit Arm PF00514.23 VBB30032.1 - 0.9 9.7 9.7 18 5.5 0.6 4.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 VBB30032.1 - 5.4 6.7 8.5 18 5.0 0.1 4.9 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 VBB30033.1 - 4e-05 24.1 6.0 0.087 13.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB30033.1 - 0.00011 22.6 4.0 1.8 9.1 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30033.1 - 0.018 15.7 5.4 3.4 8.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat FlgT_M PF16539.5 VBB30033.1 - 0.048 13.8 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain TPR_4 PF07721.14 VBB30033.1 - 0.13 13.0 5.0 24 5.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 VBB30033.1 - 0.27 10.8 8.0 0.4 10.3 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 VBB30033.1 - 1.2 9.9 8.1 1.9 9.2 8.1 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein TPR_2 PF07719.17 VBB30033.1 - 1.2 9.4 14.8 52 4.3 0.1 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB30033.1 - 3.1 8.2 12.6 23 5.5 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Ldl_recept_b PF00058.17 VBB30035.1 - 1.3e-19 70.4 3.3 1.4e-06 28.6 0.0 4.8 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 VBB30035.1 - 5.2e-07 29.8 19.3 8e-06 26.0 7.9 4.6 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A EGF_CA PF07645.15 VBB30035.1 - 8.4e-06 25.9 6.9 8.4e-06 25.9 6.9 5.1 3 1 1 4 4 4 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 VBB30035.1 - 0.00045 20.4 6.6 0.00045 20.4 6.6 4.1 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site SGL PF08450.12 VBB30035.1 - 0.027 14.0 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 VBB30035.1 - 7.7 6.6 15.2 1.4 8.9 2.2 4.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like Ras PF00071.22 VBB30036.1 - 1.5e-62 210.0 0.4 2.2e-62 209.5 0.4 1.3 1 0 0 1 1 1 1 Ras family UQ_con PF00179.26 VBB30036.1 - 1.9e-40 137.7 0.1 3.3e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Roc PF08477.13 VBB30036.1 - 3.3e-35 120.9 0.1 6.4e-35 120.0 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB30036.1 - 1.7e-12 47.2 0.0 2.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB30036.1 - 4.3e-05 23.6 0.0 9.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 VBB30036.1 - 7.7e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 VBB30036.1 - 0.0018 17.8 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB30036.1 - 0.0029 17.5 0.0 0.89 9.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase B12-binding PF02310.19 VBB30036.1 - 0.012 15.6 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain AAA_16 PF13191.6 VBB30036.1 - 0.048 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Exog_C PF18026.1 VBB30036.1 - 0.091 12.8 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Tfb2_C PF18307.1 VBB30036.1 - 0.11 12.9 0.4 26 5.4 0.1 3.1 3 0 0 3 3 3 0 Transcription factor Tfb2 (p52) C-terminal domain CTP_transf_like PF01467.26 VBB30037.1 - 2.8e-22 79.5 0.0 3.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like WD40 PF00400.32 VBB30041.1 - 3.6e-59 195.3 24.0 4.5e-08 33.6 0.2 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30041.1 - 3e-22 78.7 7.1 2.1e-06 27.9 0.9 6.3 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB30041.1 - 8.5e-09 35.6 0.1 0.0019 18.1 0.0 4.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 VBB30041.1 - 3.2e-08 34.0 0.1 6.3e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 VBB30041.1 - 1.2e-07 31.0 0.2 0.3 10.0 0.3 5.3 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 VBB30041.1 - 0.00016 20.1 0.0 0.68 8.2 0.0 3.0 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 VBB30041.1 - 0.00077 19.3 0.1 0.13 12.2 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 VBB30041.1 - 0.003 16.9 0.0 1.5 8.1 0.0 3.4 3 1 0 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 VBB30041.1 - 0.027 13.2 0.1 0.83 8.3 0.0 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Inhibitor_I36 PF03995.13 VBB30041.1 - 0.033 14.1 0.2 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Nup160 PF11715.8 VBB30041.1 - 0.26 9.9 3.8 59 2.1 0.1 4.5 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Proteasome PF00227.26 VBB30042.1 - 5.5e-40 136.9 0.0 3.1e-38 131.2 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 VBB30042.1 - 2.1e-13 49.7 1.1 2.9e-13 49.2 0.3 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NDUF_B6 PF09782.9 VBB30044.1 - 2.1e-43 148.2 2.2 3.1e-43 147.6 2.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit tRNA_synthFbeta PF17759.1 VBB30045.1 - 2.8e-45 154.4 0.0 4.3e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 VBB30045.1 - 5.5e-31 106.6 1.0 5.5e-30 103.4 0.2 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 VBB30045.1 - 5.7e-24 84.7 0.1 1e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 VBB30045.1 - 3.3e-20 72.1 0.3 4.5e-17 62.1 0.1 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain z-alpha PF02295.17 VBB30045.1 - 0.15 12.2 0.4 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain DUF2740 PF10872.8 VBB30045.1 - 0.17 11.8 0.5 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) EMC3_TMCO1 PF01956.16 VBB30046.1 - 5.7e-38 130.3 0.4 7.1e-38 130.0 0.4 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Wzy_C PF04932.15 VBB30046.1 - 0.0099 15.5 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 O-Antigen ligase TssO PF17561.2 VBB30046.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO CHD5 PF04420.14 VBB30046.1 - 0.019 14.9 0.3 0.031 14.1 0.3 1.3 1 0 0 1 1 1 0 CHD5-like protein 7TM_GPCR_Srx PF10328.9 VBB30046.1 - 0.02 14.5 0.7 4.9 6.7 0.1 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Exonuc_VII_L PF02601.15 VBB30046.1 - 0.026 14.1 0.3 0.034 13.7 0.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ArsP_1 PF03773.13 VBB30046.1 - 0.049 12.8 0.1 0.076 12.1 0.1 1.2 1 0 0 1 1 1 0 Predicted permease DUF3333 PF11812.8 VBB30046.1 - 0.078 13.2 1.7 0.11 12.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Connexin PF00029.19 VBB30046.1 - 0.11 12.3 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Connexin DivIC PF04977.15 VBB30046.1 - 0.17 11.7 3.4 0.48 10.2 3.4 1.7 1 1 0 1 1 1 0 Septum formation initiator TRAM1 PF08390.11 VBB30046.1 - 0.22 11.2 1.1 0.3 10.8 0.1 1.7 2 0 0 2 2 2 0 TRAM1-like protein CENP-Q PF13094.6 VBB30046.1 - 2.6 8.2 8.5 0.85 9.8 6.0 1.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LapA_dom PF06305.11 VBB30046.1 - 3.8 7.4 8.0 2.3 8.1 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 VBB30047.1 - 4.5e-64 216.4 0.0 6.1e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30047.1 - 4.9e-29 101.4 0.0 7.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 VBB30047.1 - 5.9e-05 22.2 0.2 5.9e-05 22.2 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 VBB30047.1 - 0.00024 20.5 0.0 0.00048 19.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB30047.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB30047.1 - 0.0073 15.1 0.1 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 VBB30047.1 - 0.057 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DprA_WH PF17782.1 VBB30047.1 - 0.19 11.8 2.4 0.92 9.7 2.2 2.1 2 0 0 2 2 2 0 DprA winged helix domain Blt1 PF12754.7 VBB30047.1 - 1.1 9.6 4.0 5.9 7.2 4.0 2.4 1 1 0 1 1 1 0 Blt1 N-terminal domain MPC PF03650.13 VBB30049.1 - 9.1e-32 109.5 0.1 1.9e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers SlyX PF04102.12 VBB30049.1 - 0.022 15.4 2.8 0.063 13.9 2.8 1.7 1 0 0 1 1 1 0 SlyX DUF3217 PF11506.8 VBB30049.1 - 0.038 14.0 0.2 0.087 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) MgtE PF01769.16 VBB30049.1 - 0.04 14.3 2.8 4.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Divalent cation transporter PDZ_2 PF13180.6 VBB30049.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain zf-LITAF-like PF10601.9 VBB30049.1 - 0.58 10.5 5.7 2.3 8.6 5.7 2.0 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Pkinase PF00069.25 VBB30050.1 - 3.8e-26 92.0 0.1 5.4e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30050.1 - 9.8e-13 48.0 0.1 1.4e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB30050.1 - 0.0013 18.7 0.0 0.0041 17.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 VBB30050.1 - 0.0016 17.9 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 VBB30050.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-RING_9 PF13901.6 VBB30051.1 - 1.8e-62 211.0 8.4 1.8e-62 211.0 8.4 1.9 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon zf-UDP PF14569.6 VBB30051.1 - 4.8 7.4 13.3 0.87 9.8 8.5 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger TRAUB PF08164.12 VBB30052.1 - 2.1e-25 89.0 2.5 2.1e-25 89.0 2.5 3.0 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 VBB30052.1 - 6.6e-13 49.5 5.1 6.6e-13 49.5 5.1 3.4 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor MOLO1 PF17175.4 VBB30053.1 - 7.9e-11 42.1 0.2 3.6e-10 40.0 0.2 2.0 1 1 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 VBB30053.1 - 0.0062 16.7 0.3 0.015 15.4 0.3 1.7 1 1 0 1 1 1 1 TPM domain Ribosomal_L3 PF00297.22 VBB30054.1 - 1.6e-173 576.9 12.0 1.9e-173 576.7 12.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 EnY2 PF10163.9 VBB30055.1 - 6.5e-27 93.7 0.4 7.4e-27 93.6 0.4 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 UPF0167 PF03691.14 VBB30055.1 - 0.037 13.8 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) SH2 PF00017.24 VBB30056.1 - 4.2e-20 71.6 0.1 1.6e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 SH2 domain SH3_2 PF07653.17 VBB30056.1 - 1.1e-15 57.0 0.1 9.6e-11 41.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 VBB30056.1 - 8e-12 44.6 0.0 3.1e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 VBB30056.1 - 1.2e-09 37.9 0.1 5.4e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain C1_1 PF00130.22 VBB30056.1 - 7.1e-08 32.2 12.6 1.5e-07 31.2 12.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB30056.1 - 0.034 14.5 11.0 0.069 13.5 11.0 1.5 1 0 0 1 1 1 0 C1 domain AvrPtoB_bdg PF16847.5 VBB30057.1 - 0.13 12.8 0.2 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain DUF3593 PF12159.8 VBB30058.1 - 5 7.2 8.8 1.6 8.8 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) Staufen_C PF16482.5 VBB30060.1 - 2.1e-11 44.0 0.0 3.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Staufen C-terminal domain SLC35F PF06027.12 VBB30061.1 - 2.2e-57 194.8 4.6 2.8e-57 194.5 4.6 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 VBB30061.1 - 1.6e-06 27.3 1.2 2.1e-06 26.9 1.2 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 VBB30061.1 - 1.5e-05 25.2 9.6 2.1e-05 24.7 9.6 1.2 1 0 0 1 1 1 1 EamA-like transporter family UAA PF08449.11 VBB30061.1 - 0.013 14.7 2.6 0.019 14.2 2.6 1.2 1 0 0 1 1 1 0 UAA transporter family Ribosomal_L9_N PF01281.19 VBB30062.1 - 2.9e-13 49.1 0.1 5.1e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain zf-CCCH PF00642.24 VBB30063.1 - 8.3e-06 25.6 16.5 5.9e-05 22.9 4.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 VBB30063.1 - 5.3e-05 23.0 0.1 9.2e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 VBB30063.1 - 0.0031 18.2 3.0 0.037 14.7 0.4 2.5 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 VBB30063.1 - 0.008 16.2 0.1 0.021 14.8 0.1 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 VBB30063.1 - 0.01 16.1 3.9 1.3 9.2 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 VBB30063.1 - 0.012 15.6 3.1 0.012 15.6 3.1 2.8 2 0 0 2 2 2 0 Zinc finger domain zf-H2C2_2 PF13465.6 VBB30064.1 - 1e-15 57.3 20.8 1.9e-08 34.4 0.8 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 VBB30064.1 - 3.8e-09 36.5 32.2 0.00029 21.1 1.8 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB30064.1 - 6.7e-08 32.7 24.7 0.0058 17.4 1.0 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.12 VBB30064.1 - 0.14 12.5 18.8 1.6 9.1 2.9 3.6 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 VBB30064.1 - 0.41 9.8 5.9 13 4.8 5.9 2.5 1 1 0 1 1 1 0 Putative actin-like family zf-BED PF02892.15 VBB30064.1 - 0.5 10.4 18.4 0.31 11.1 0.5 3.7 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 VBB30064.1 - 1.4 9.3 15.6 12 6.3 0.7 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 VBB30064.1 - 1.7 8.8 14.7 0.42 10.8 3.9 3.1 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 VBB30064.1 - 4 7.8 7.7 8.4 6.8 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 VBB30064.1 - 6.8 7.5 11.6 45 4.9 4.4 3.1 1 1 1 2 2 2 0 zinc-ribbon family Snapin_Pallidin PF14712.6 VBB30065.1 - 0.0014 19.0 0.4 0.0021 18.4 0.4 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF4577 PF15145.6 VBB30065.1 - 0.0024 17.9 0.6 0.003 17.6 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4577) DUF4972 PF16342.5 VBB30065.1 - 0.074 12.7 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF2935 PF11155.8 VBB30065.1 - 0.095 13.0 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Ephrin PF00812.17 VBB30066.1 - 4.4e-29 101.2 0.0 7.3e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Ephrin CYLD_phos_site PF16607.5 VBB30066.1 - 0.033 14.0 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured RRM_1 PF00076.22 VBB30067.1 - 0.00093 19.0 0.0 0.002 17.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KCT2 PF17818.1 VBB30068.1 - 1.5e-08 35.0 1.3 2.6e-08 34.2 1.3 1.6 1 1 0 1 1 1 1 Keratinocyte-associated gene product Alpha_L_fucos PF01120.17 VBB30069.1 - 6.2e-109 364.7 12.1 8.3e-109 364.2 12.1 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase Peptidase_M16 PF00675.20 VBB30069.1 - 1.3e-08 35.0 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 VBB30069.1 - 4.8e-08 33.2 0.0 1.8e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Fucosidase_C PF16757.5 VBB30069.1 - 0.039 14.5 0.1 0.11 13.1 0.1 1.8 1 1 0 1 1 1 0 Alpha-L-fucosidase C-terminal domain Aminotran_4 PF01063.19 VBB30070.1 - 6.7e-29 101.3 0.0 1.4e-27 97.0 0.0 2.0 2 0 0 2 2 2 2 Amino-transferase class IV Macro PF01661.21 VBB30074.1 - 5.7e-35 119.9 0.5 2.1e-34 118.1 0.5 2.0 2 0 0 2 2 2 1 Macro domain BTB_2 PF02214.22 VBB30074.1 - 3.3e-23 81.8 0.0 6.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 VBB30074.1 - 0.0047 17.7 4.0 1.2 10.1 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30074.1 - 0.011 16.0 0.0 2.3 8.6 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 VBB30074.1 - 0.053 13.6 0.4 0.76 9.8 0.3 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region BTB_3 PF16017.5 VBB30074.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain DnaJ PF00226.31 VBB30075.1 - 1.7e-20 72.9 0.4 1.7e-20 72.9 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 VBB30075.1 - 3.1e-05 23.7 0.0 0.0014 18.4 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_11 PF13086.6 VBB30075.1 - 0.49 10.1 7.7 0.71 9.6 7.7 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 VBB30075.1 - 0.72 9.0 3.1 1 8.6 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Goodbye PF17109.5 VBB30075.1 - 6.1 7.3 6.0 59 4.1 3.1 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain TMEM70 PF06979.12 VBB30076.1 - 1.5e-16 61.0 0.8 1.5e-16 61.0 0.8 1.8 2 0 0 2 2 2 1 Assembly, mitochondrial proton-transport ATP synth complex Trypsin PF00089.26 VBB30076.1 - 1.7e-06 28.0 0.0 3.8e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 VBB30076.1 - 0.0033 18.3 0.0 0.005 17.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Vma12 PF11712.8 VBB30077.1 - 6e-29 100.9 0.0 1.4e-28 99.7 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase UCH PF00443.29 VBB30078.1 - 2.2e-37 128.9 0.0 4.7e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB30078.1 - 1.8e-18 67.2 0.9 3.2e-14 53.2 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PPP4R2 PF09184.11 VBB30078.1 - 4.2 6.9 6.8 6.9 6.2 6.8 1.4 1 0 0 1 1 1 0 PPP4R2 MCD PF05292.11 VBB30080.1 - 1.6e-86 290.0 0.0 2.7e-86 289.3 0.0 1.3 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 VBB30080.1 - 4.3e-10 39.6 0.0 1.1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain GSCFA PF08885.11 VBB30080.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.5 1 1 0 1 1 1 0 GSCFA family Lactamase_B_6 PF16661.5 VBB30081.1 - 1.2e-09 37.9 0.0 8.6e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 VBB30081.1 - 3e-09 37.1 0.0 6.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 VBB30081.1 - 0.00055 19.2 0.0 0.0017 17.6 0.0 1.8 1 0 0 1 1 1 1 Putative beta-lactamase-like family S4 PF01479.25 VBB30082.1 - 0.00028 20.5 0.5 0.00079 19.1 0.5 1.8 1 1 0 1 1 1 1 S4 domain DHHC PF01529.20 VBB30084.1 - 1.5e-19 70.4 13.2 1.5e-19 70.4 13.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase HypA PF01155.19 VBB30084.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5356 PF17309.2 VBB30085.1 - 0.029 14.4 0.2 0.035 14.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5356) Cpn60_TCP1 PF00118.24 VBB30086.1 - 3.1e-155 517.6 12.7 3.6e-155 517.3 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2624 PF11116.8 VBB30086.1 - 0.45 11.4 4.3 1.2 10.1 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2624) Myosin_tail_1 PF01576.19 VBB30087.1 - 1e-75 255.4 161.2 1.4e-75 254.9 161.2 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 VBB30087.1 - 1.1e-06 28.5 54.7 1.1e-06 28.5 54.7 4.7 1 1 3 4 4 4 2 Intermediate filament protein LktC PF06261.11 VBB30087.1 - 0.084 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC ERM PF00769.19 VBB30087.1 - 7.2 6.3 164.7 0.16 11.8 31.0 6.5 1 1 5 6 6 6 0 Ezrin/radixin/moesin family 7tm_1 PF00001.21 VBB30088.1 - 1.6e-18 67.0 21.6 1.6e-18 67.0 21.6 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) AMPK1_CBM PF16561.5 VBB30091.1 - 3.8e-29 100.7 0.4 6.3e-29 100.0 0.4 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 VBB30091.1 - 1.9e-27 95.3 4.6 3.1e-27 94.6 4.6 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Herpes_UL6 PF01763.16 VBB30092.1 - 0.004 15.7 0.6 0.0045 15.6 0.6 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like Striatin PF08232.12 VBB30092.1 - 0.006 17.2 3.8 0.0085 16.7 3.8 1.2 1 0 0 1 1 1 1 Striatin family Noelin-1 PF12308.8 VBB30092.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Neurogenesis glycoprotein PI3K_1B_p101 PF10486.9 VBB30092.1 - 0.055 11.3 2.9 0.056 11.2 2.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YopE PF03545.13 VBB30092.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Mito_carr PF00153.27 VBB30093.1 - 1.4e-57 191.6 2.8 2.5e-21 75.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mo-co_dimer PF03404.16 VBB30094.1 - 4.5e-38 130.4 0.0 9.3e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Band_7 PF01145.25 VBB30094.1 - 7.5e-30 104.2 0.4 1.2e-29 103.6 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Oxidored_molyb PF00174.19 VBB30094.1 - 3.2e-29 101.7 0.0 7.4e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Cyt-b5 PF00173.28 VBB30094.1 - 3.7e-10 39.8 0.0 6.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Band_7_1 PF13421.6 VBB30094.1 - 0.011 15.5 0.2 0.018 14.7 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family BNR PF02012.20 VBB30094.1 - 0.13 12.3 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat GP68 PF17469.2 VBB30094.1 - 0.17 12.3 0.2 0.4 11.1 0.2 1.5 1 0 0 1 1 1 0 Phage protein Gp68 Big_7 PF17957.1 VBB30094.1 - 0.26 12.1 1.1 1.7 9.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial Ig domain Collagen PF01391.18 VBB30095.1 - 2.1e-24 85.0 104.3 3.6e-10 39.4 35.6 4.0 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB30095.1 - 1.6e-20 72.9 0.5 2e-20 72.5 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF148 PF02520.17 VBB30096.1 - 0.007 16.5 0.4 0.012 15.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF3043 PF11241.8 VBB30096.1 - 0.13 12.3 1.5 0.16 12.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MNR PF15718.5 VBB30097.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein moonraker ShK PF01549.24 VBB30098.1 - 2e-17 63.4 18.2 3.4e-09 37.1 5.0 2.2 2 0 0 2 2 2 2 ShK domain-like BTB PF00651.31 VBB30099.1 - 1.8e-15 57.1 0.1 1e-14 54.7 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 VBB30099.1 - 2.7e-11 43.5 0.1 1.3e-10 41.3 0.1 2.0 1 1 0 1 1 1 1 BTB And C-terminal Kelch hnRNP_Q_AcD PF18360.1 VBB30099.1 - 0.0077 16.2 0.1 0.027 14.4 0.1 2.0 1 1 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain CAAP1 PF15335.6 VBB30099.1 - 0.17 12.4 0.1 2 9.0 0.0 2.3 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 P5CR_dimer PF14748.6 VBB30101.1 - 2.4e-34 117.7 3.3 2.4e-34 117.7 3.3 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 VBB30101.1 - 3.4e-10 40.3 0.0 6.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF2063 PF09836.9 VBB30102.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain HARP PF07443.13 VBB30103.1 - 0.048 13.3 1.2 0.72 9.5 0.3 2.4 2 0 0 2 2 2 0 HepA-related protein (HARP) Aa_trans PF01490.18 VBB30104.1 - 2.3e-39 135.3 35.7 2.8e-39 135.0 35.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAT PF16073.5 VBB30104.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis HIT PF01230.23 VBB30106.1 - 8.6e-31 106.6 0.2 1e-30 106.3 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 VBB30106.1 - 2.2e-23 82.9 0.1 2.7e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_C1 PF00112.23 VBB30107.1 - 1e-37 130.4 8.7 1.6e-37 129.7 8.7 1.4 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 VBB30107.1 - 0.27 9.9 0.9 0.43 9.3 0.9 1.3 1 0 0 1 1 1 0 Peptidase C1-like family DUF2807 PF10988.8 VBB30108.1 - 0.048 13.4 0.2 0.067 13.0 0.2 1.1 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Myotub-related PF06602.14 VBB30109.1 - 3.2e-102 342.1 0.5 6.1e-69 232.6 0.5 2.3 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain FYVE PF01363.21 VBB30109.1 - 1.3e-05 25.2 11.4 4.5e-05 23.5 11.4 2.0 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 VBB30109.1 - 2.8 8.2 8.8 8.2 6.7 5.8 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Spb1_C PF07780.12 VBB30110.1 - 4.9e-61 206.1 22.4 4.9e-61 206.1 22.4 3.6 2 1 2 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 VBB30110.1 - 1.1e-58 198.3 0.4 2.5e-58 197.1 0.1 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 VBB30110.1 - 2e-29 102.5 13.2 2e-29 102.5 13.2 5.2 4 2 2 6 6 6 1 Domain of unknown function (DUF3381) Arfaptin PF06456.13 VBB30112.1 - 9.1e-63 211.9 8.2 1.5e-62 211.1 8.2 1.3 1 0 0 1 1 1 1 Arfaptin-like domain Mating_N PF12731.7 VBB30112.1 - 0.011 15.8 0.4 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Mating-type protein beta 1 FHA PF00498.26 VBB30113.1 - 3.7e-18 65.6 0.0 1.1e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 VBB30113.1 - 4.1e-05 23.8 0.0 0.0018 18.5 0.0 2.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain p25-alpha PF05517.12 VBB30114.1 - 8.6e-45 152.7 3.7 1.1e-44 152.3 3.7 1.1 1 0 0 1 1 1 1 p25-alpha Ribosomal_L13e PF01294.18 VBB30115.1 - 4.3e-78 261.3 6.0 6e-78 260.8 6.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF4710 PF15828.5 VBB30116.1 - 0.51 10.5 13.7 0.36 11.0 10.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4710) AMP-binding PF00501.28 VBB30117.1 - 2.2e-65 220.9 0.0 3.1e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 VBB30117.1 - 9.3e-19 67.6 0.1 1.8e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 VBB30117.1 - 2.7e-09 37.9 0.7 4.6e-08 33.9 0.1 2.8 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Nodulin-like PF06813.13 VBB30117.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Nodulin-like NAD_binding_4 PF07993.12 VBB30117.1 - 0.08 12.1 2.8 0.086 12.0 1.7 1.7 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 VBB30117.1 - 0.84 9.0 3.1 0.44 10.0 0.5 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 VBB30117.1 - 1.3 8.4 3.9 0.33 10.3 0.5 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DHHC PF01529.20 VBB30118.1 - 4.4e-08 33.3 21.3 3.4e-05 24.0 7.2 3.3 3 0 0 3 3 3 2 DHHC palmitoyltransferase DUF4179 PF13786.6 VBB30118.1 - 0.16 12.5 0.2 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) AA_permease PF00324.21 VBB30119.1 - 5.6e-59 200.0 30.2 1.1e-42 146.2 2.9 2.1 2 0 0 2 2 2 2 Amino acid permease ESAG1 PF03238.13 VBB30120.1 - 0.096 12.1 1.1 0.12 11.8 1.1 1.1 1 0 0 1 1 1 0 ESAG protein Myc_target_1 PF15179.6 VBB30121.1 - 0.01 15.8 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 1 Myc target protein 1 RIFIN PF02009.16 VBB30121.1 - 0.049 13.5 0.1 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 Rifin Ly49 PF08391.10 VBB30121.1 - 0.053 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DSL PF01414.19 VBB30121.1 - 0.094 13.0 1.4 0.21 11.9 1.0 1.7 1 1 0 1 1 1 0 Delta serrate ligand Insulin_TMD PF17870.1 VBB30121.1 - 2.4 8.3 5.1 5.8 7.1 5.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment T-box PF00907.22 VBB30123.1 - 1.7e-78 263.1 0.2 2.3e-78 262.7 0.2 1.2 1 0 0 1 1 1 1 T-box 7tm_1 PF00001.21 VBB30125.1 - 2.1e-18 66.6 0.1 2.2e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YwcE PF17368.2 VBB30125.1 - 0.035 14.8 0.5 0.048 14.3 0.5 1.2 1 0 0 1 1 1 0 Spore morphogenesis and germination YwcE 7TM_GPCR_Srsx PF10320.9 VBB30125.1 - 0.037 13.4 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Guanylate_kin PF00625.21 VBB30126.1 - 1.5e-40 138.8 0.0 2.7e-37 128.2 0.0 2.4 2 0 0 2 2 2 2 Guanylate kinase PDZ_6 PF17820.1 VBB30126.1 - 1.3e-11 44.1 0.2 2.8e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB30126.1 - 1.4e-11 44.6 0.3 2.7e-11 43.6 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB30126.1 - 0.00041 20.6 0.1 0.00086 19.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 VBB30126.1 - 0.0087 15.6 0.1 0.045 13.4 0.1 2.3 1 1 0 1 1 1 1 SH3 domain AAA_22 PF13401.6 VBB30126.1 - 0.08 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 VBB30126.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) JAB PF01398.21 VBB30127.1 - 1.7e-24 86.1 0.5 1.4e-23 83.1 0.1 2.5 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 VBB30127.1 - 1.2e-09 38.6 0.6 2.8e-09 37.4 0.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 VBB30127.1 - 2.7e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1154 PF06631.11 VBB30127.1 - 0.21 11.6 1.5 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Anillin PF08174.11 VBB30128.1 - 1e-27 97.3 0.0 2.7e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Cell division protein anillin CBM_14 PF01607.24 VBB30129.1 - 7.2e-17 61.3 2.5 7.8e-17 61.2 2.5 1.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 VBB30129.1 - 0.036 14.1 1.7 0.045 13.8 0.9 1.7 1 1 1 2 2 2 0 Carbohydrate binding domain (family 19) HTH_Tnp_Tc5 PF03221.16 VBB30130.1 - 2.7e-13 49.7 0.5 5.3e-13 48.8 0.5 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain ANAPC4_WD40 PF12894.7 VBB30131.1 - 4.9e-11 42.8 0.4 0.0066 16.7 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB30131.1 - 2.4e-09 37.7 7.2 0.084 13.8 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 VBB30131.1 - 0.00037 20.4 2.1 0.03 14.2 0.1 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A DFP PF04127.15 VBB30132.1 - 2.6e-19 69.8 0.0 2e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HMG_box PF00505.19 VBB30133.1 - 6.3e-17 61.7 1.8 6.3e-17 61.7 1.8 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB30133.1 - 2.3e-06 28.1 0.8 2.3e-06 28.1 0.8 2.3 2 1 1 3 3 3 1 HMG-box domain IFP_35_N PF07334.13 VBB30133.1 - 0.0034 17.4 1.7 0.01 15.9 1.7 1.8 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3802 PF12290.8 VBB30133.1 - 0.048 14.2 0.2 3.8 8.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) PocR PF10114.9 VBB30133.1 - 0.15 11.8 1.6 0.83 9.4 0.0 2.6 2 1 0 3 3 3 0 Sensory domain found in PocR CdiI_2 PF18593.1 VBB30133.1 - 3.5 8.3 5.4 0.79 10.4 0.3 2.5 3 0 0 3 3 3 0 CdiI immunity protein 7tm_3 PF00003.22 VBB30136.1 - 1.2e-05 25.2 4.0 1.5e-05 24.9 4.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4534 PF15049.6 VBB30136.1 - 0.11 12.2 3.4 0.19 11.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Ribosomal_S26e PF01283.19 VBB30137.1 - 1.1e-52 177.0 6.2 2.5e-52 175.9 6.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S26e DnaJ_C PF01556.18 VBB30137.1 - 1.8e-42 144.9 0.3 3.1e-42 144.2 0.3 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 VBB30137.1 - 1.3e-26 92.5 1.6 2.4e-26 91.6 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain TMEM107 PF14995.6 VBB30137.1 - 4.6e-22 78.7 9.1 9.1e-22 77.8 9.1 1.4 1 0 0 1 1 1 1 Transmembrane protein DnaJ_CXXCXGXG PF00684.19 VBB30137.1 - 1.6e-13 50.8 19.4 1.6e-13 50.8 19.4 2.4 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 VBB30137.1 - 5 7.2 19.2 0.76 9.8 1.1 3.0 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-LITAF-like PF10601.9 VBB30138.1 - 1.2e-21 76.7 9.2 2.2e-21 75.9 9.2 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-RING_7 PF02591.15 VBB30138.1 - 0.063 13.5 4.8 0.12 12.6 0.7 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain RNA_pol_N PF01194.17 VBB30139.1 - 5.1e-32 110.0 0.3 5.7e-32 109.8 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 VBB30139.1 - 0.047 13.9 0.6 0.082 13.2 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Prefoldin_2 PF01920.20 VBB30140.1 - 1.3e-15 57.2 9.0 1.5e-15 57.0 9.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Uds1 PF15456.6 VBB30140.1 - 0.027 14.6 6.2 0.041 14.0 6.2 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF4315 PF14193.6 VBB30140.1 - 0.041 13.9 6.3 0.041 13.9 6.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) AIF-MLS PF14962.6 VBB30140.1 - 0.044 13.8 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF724 PF05266.14 VBB30140.1 - 0.22 11.3 8.1 0.42 10.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2175 PF09943.9 VBB30140.1 - 0.53 10.6 8.8 2.2 8.6 2.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) ATG16 PF08614.11 VBB30140.1 - 0.72 10.0 12.6 0.7 10.1 1.7 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) XhlA PF10779.9 VBB30140.1 - 3.2 8.0 8.5 0.28 11.4 2.3 2.2 2 1 0 2 2 2 0 Haemolysin XhlA MbeB_N PF04837.12 VBB30140.1 - 4.5 7.7 12.0 3.8 7.9 0.5 3.7 3 1 1 4 4 4 0 MbeB-like, N-term conserved region TPR_2 PF07719.17 VBB30142.1 - 1.2e-18 65.6 19.1 0.00012 21.9 0.1 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 VBB30142.1 - 3.8e-18 64.5 18.6 1e-06 28.3 0.2 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30142.1 - 7.5e-16 57.5 18.9 3.9e-05 23.2 0.2 5.5 4 1 1 5 5 5 4 TPR repeat TPR_19 PF14559.6 VBB30142.1 - 1.5e-14 54.2 13.7 9.6e-06 26.0 0.4 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB30142.1 - 2.4e-14 52.3 11.8 0.0017 18.4 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30142.1 - 4.5e-12 45.7 8.8 0.0058 17.4 0.2 5.4 2 2 4 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB30142.1 - 5e-10 39.5 12.7 4.2e-07 30.2 2.8 4.1 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30142.1 - 1.3e-09 38.5 8.0 0.00016 22.2 0.6 4.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30142.1 - 2.9e-08 33.5 16.6 0.021 15.2 0.3 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 VBB30142.1 - 4.4e-08 32.7 7.1 0.00036 19.8 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB30142.1 - 6.5e-06 26.3 11.7 0.0023 18.1 0.7 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 VBB30142.1 - 0.00012 21.9 6.9 0.0082 16.1 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 VBB30142.1 - 0.00013 22.2 4.8 0.52 10.7 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB30142.1 - 0.0019 18.0 11.8 0.099 12.5 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB30142.1 - 0.013 15.6 3.0 0.14 12.3 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 VBB30142.1 - 0.022 15.3 6.5 0.79 10.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 VBB30142.1 - 1.9 8.6 7.0 3.7 7.7 0.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 VBB30142.1 - 6.3 6.3 7.4 3.1 7.3 0.3 2.8 3 0 0 3 3 3 0 SHNi-TPR ATP-synt_F PF01990.17 VBB30143.1 - 5.1e-31 106.9 0.2 5.8e-31 106.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit SapB_1 PF05184.15 VBB30143.1 - 0.17 11.9 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 CLP_protease PF00574.23 VBB30144.1 - 1.3e-75 253.2 0.5 1.6e-75 253.0 0.5 1.0 1 0 0 1 1 1 1 Clp protease RabGAP-TBC PF00566.18 VBB30145.1 - 5.6e-45 153.6 7.4 8e-45 153.1 7.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 VBB30145.1 - 3.8e-17 62.3 0.0 9.3e-17 61.0 0.0 1.6 1 1 0 1 1 1 1 Rab-binding domain (RBD) Ephrin_rec_like PF07699.13 VBB30147.1 - 5.5e-40 134.9 40.6 1.5e-14 53.5 4.4 5.0 4 1 0 4 4 4 4 Putative ephrin-receptor like EGF_3 PF12947.7 VBB30147.1 - 3.5e-10 39.9 21.2 1.2e-07 31.8 5.6 4.1 3 0 0 3 3 3 2 EGF domain EGF PF00008.27 VBB30147.1 - 1.5e-07 31.6 21.9 5.5e-06 26.6 7.3 5.4 6 0 0 6 6 6 2 EGF-like domain hEGF PF12661.7 VBB30147.1 - 4.4e-05 23.9 8.6 0.00026 21.5 2.7 7.5 8 1 0 8 8 8 2 Human growth factor-like EGF cEGF PF12662.7 VBB30147.1 - 0.00034 20.5 4.1 0.00034 20.5 4.1 7.4 6 2 1 7 7 7 2 Complement Clr-like EGF-like DUF2318 PF10080.9 VBB30147.1 - 0.074 13.2 24.1 0.57 10.3 1.1 4.3 1 1 2 4 4 4 0 Predicted membrane protein (DUF2318) TNFR_c6 PF00020.18 VBB30147.1 - 0.27 11.7 0.3 0.27 11.7 0.3 9.8 7 5 4 11 11 11 0 TNFR/NGFR cysteine-rich region Homeodomain PF00046.29 VBB30148.1 - 3.5e-22 78.0 4.3 6.6e-22 77.1 4.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB30148.1 - 0.0044 16.9 0.3 0.0044 16.9 0.3 2.4 3 0 0 3 3 3 1 Homeobox KN domain PHC2_SAM_assoc PF16616.5 VBB30148.1 - 5.6 7.8 7.7 3 8.7 1.4 2.3 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 SEA PF01390.20 VBB30149.1 - 0.00027 21.0 0.0 0.00065 19.8 0.0 1.7 1 0 0 1 1 1 1 SEA domain Shisa PF13908.6 VBB30149.1 - 0.054 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SNARE PF05739.19 VBB30149.1 - 0.21 11.6 1.0 0.52 10.3 1.0 1.7 1 0 0 1 1 1 0 SNARE domain Homeodomain PF00046.29 VBB30150.1 - 3.5e-14 52.4 3.5 1.1e-08 34.7 0.2 2.9 2 1 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 VBB30150.1 - 0.0019 18.1 0.5 0.081 12.8 0.1 2.9 2 0 0 2 2 2 1 Homeobox KN domain AEP1 PF17049.5 VBB30150.1 - 0.069 12.2 0.5 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 ATPase expression protein 1 Pkinase PF00069.25 VBB30151.1 - 9.8e-14 51.3 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30151.1 - 2.5e-05 23.7 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB30151.1 - 0.0063 15.3 0.1 0.012 14.5 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB30151.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RnaseA PF00074.20 VBB30151.1 - 0.026 15.0 1.0 0.026 15.0 1.0 2.0 2 0 0 2 2 2 0 Pancreatic ribonuclease KduI PF04962.12 VBB30151.1 - 0.029 13.7 0.0 0.93 8.7 0.0 2.3 2 0 0 2 2 2 0 KduI/IolB family PKD PF00801.20 VBB30151.1 - 0.048 13.5 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 PKD domain TraP PF07296.11 VBB30151.1 - 0.15 11.3 0.5 13 4.9 0.1 2.8 2 1 0 2 2 2 0 TraP protein Kinesin_assoc PF16183.5 VBB30151.1 - 0.43 10.7 1.6 1.4 9.0 1.6 1.9 1 0 0 1 1 1 0 Kinesin-associated PHR PF08005.12 VBB30152.1 - 7.7e-35 120.8 0.1 1.4e-34 119.9 0.1 1.5 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 VBB30152.1 - 9.7e-20 70.9 0.0 2.3e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TPR_2 PF07719.17 VBB30152.1 - 1.5e-08 34.1 1.7 8.2 6.8 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB30152.1 - 2.1e-06 27.4 6.6 0.32 11.1 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30152.1 - 3.8e-06 26.5 4.8 0.8 9.4 0.0 6.1 6 1 1 7 7 7 2 TPR repeat BACK PF07707.15 VBB30152.1 - 5e-06 26.5 0.8 5e-06 26.5 0.8 3.0 2 1 1 3 3 3 1 BTB And C-terminal Kelch TPR_12 PF13424.6 VBB30152.1 - 7.4e-06 26.2 8.9 0.41 11.0 0.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB30152.1 - 3.5e-05 23.4 4.7 0.15 12.0 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30152.1 - 0.0003 20.9 0.7 4.4 7.9 0.0 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB30152.1 - 0.0028 16.9 2.4 0.14 11.3 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30152.1 - 0.01 16.6 9.9 9.3 7.4 0.4 5.3 4 1 2 6 6 5 0 Tetratricopeptide repeat DUF2857 PF11198.8 VBB30152.1 - 0.037 13.8 0.2 0.094 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) TPR_8 PF13181.6 VBB30152.1 - 0.045 14.0 6.3 19 5.8 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Med29 PF11568.8 VBB30153.1 - 9.3e-06 25.9 1.3 0.0052 17.0 0.9 3.5 4 0 0 4 4 4 2 Mediator complex subunit 29 ORC6 PF05460.13 VBB30153.1 - 0.82 8.9 11.8 0.43 9.8 9.8 1.5 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3523 PF12037.8 VBB30155.1 - 8.3e-87 290.9 37.3 1.3e-86 290.3 37.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 VBB30155.1 - 1.4e-22 80.5 0.0 9.3e-22 77.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 VBB30155.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 VBB30155.1 - 0.00013 22.4 0.0 0.00013 22.4 0.0 3.8 2 2 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 VBB30155.1 - 0.0011 19.1 0.0 0.0011 19.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 VBB30155.1 - 0.003 17.0 0.2 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 VBB30155.1 - 0.0045 17.3 4.2 0.27 11.5 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 VBB30155.1 - 0.0095 15.7 0.1 0.0095 15.7 0.1 2.5 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 VBB30155.1 - 0.012 15.3 1.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 VBB30155.1 - 0.016 15.8 1.7 0.11 13.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_lid_3 PF17862.1 VBB30155.1 - 0.017 14.9 0.8 0.062 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA+ lid domain RNA_helicase PF00910.22 VBB30155.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 VBB30155.1 - 0.024 14.6 7.8 0.035 14.1 0.0 3.8 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 VBB30155.1 - 0.032 14.2 0.2 0.12 12.4 0.0 2.1 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 VBB30155.1 - 0.074 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 VBB30155.1 - 0.088 13.0 0.0 0.088 13.0 0.0 4.0 3 1 1 4 4 3 0 AAA domain AAA_25 PF13481.6 VBB30155.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.8 3 1 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 VBB30155.1 - 0.2 10.7 0.0 0.2 10.7 0.0 2.5 2 1 1 3 3 3 0 Parvovirus non-structural protein NS1 Zot PF05707.12 VBB30155.1 - 0.3 10.7 0.0 0.3 10.7 0.0 3.3 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 VBB30155.1 - 0.96 9.2 0.0 0.96 9.2 0.0 3.2 2 1 1 3 3 1 0 AAA domain DUF2624 PF11116.8 VBB30155.1 - 2.3 9.2 6.7 0.32 11.9 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Robl_LC7 PF03259.17 VBB30156.1 - 6.6e-21 73.9 0.0 7.7e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 VBB30156.1 - 0.00024 21.0 0.1 0.00031 20.6 0.1 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Gal-bind_lectin PF00337.22 VBB30157.1 - 1.1e-67 225.6 0.0 8.9e-34 115.9 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin SBDS PF01172.18 VBB30157.1 - 0.4 10.8 4.1 1.2 9.3 0.1 3.2 3 1 1 4 4 4 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein 5_nucleotid PF05761.14 VBB30158.1 - 1.3e-76 258.4 0.0 1.6e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family MAM PF00629.23 VBB30160.1 - 4.2e-13 49.5 0.1 1.2e-07 31.8 0.0 2.7 2 1 0 2 2 2 2 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 VBB30161.1 - 3.9e-45 151.8 119.2 2.1e-09 37.4 11.8 9.3 8 1 1 9 9 9 8 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 VBB30161.1 - 1.4e-05 24.9 32.8 0.00014 21.7 13.9 5.3 2 1 3 5 5 5 2 Glucosidase II beta subunit-like HPD PF05044.12 VBB30162.1 - 1.2e-23 83.6 2.0 1.2e-23 83.6 2.0 2.5 2 0 0 2 2 2 1 Homeo-prospero domain Mucin PF01456.17 VBB30162.1 - 3.7 7.5 26.3 0.15 12.1 19.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein PX PF00787.24 VBB30163.1 - 1.7e-18 66.6 0.1 3.6e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 VBB30163.1 - 2.7e-16 59.7 1.1 4.7e-16 58.9 1.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB30163.1 - 5.9e-15 54.8 1.7 1.2e-14 53.9 1.3 1.7 1 1 1 2 2 2 1 PDZ domain RA PF00788.23 VBB30163.1 - 9.8e-06 26.1 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 VBB30163.1 - 1.1e-05 25.6 0.2 2.1e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 VBB30164.1 - 3.2e-14 52.9 23.1 8e-09 35.6 3.8 2.1 2 0 0 2 2 2 2 LIM domain Copper-fist PF00649.18 VBB30164.1 - 0.88 9.1 0.0 0.88 9.1 0.0 3.1 3 0 0 3 3 3 0 Copper fist DNA binding domain NDK PF00334.19 VBB30165.1 - 1.5e-56 190.2 0.0 1.8e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 VBB30165.1 - 0.16 12.5 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ SDA1 PF05285.12 VBB30166.1 - 0.036 13.5 40.7 0.062 12.7 40.7 1.4 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 VBB30166.1 - 0.056 12.2 20.0 0.43 9.3 16.3 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Pex14_N PF04695.13 VBB30166.1 - 0.43 11.2 4.0 2.4 8.8 3.9 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MscS_TM PF12794.7 VBB30166.1 - 0.81 8.5 0.0 0.81 8.5 0.0 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 LAP1C PF05609.12 VBB30166.1 - 0.84 8.7 17.4 1.4 7.9 17.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 VBB30166.1 - 1.3 7.2 43.1 2 6.5 43.1 1.3 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 VBB30166.1 - 1.9 7.2 16.8 3.4 6.3 16.8 1.5 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.10 VBB30166.1 - 5.3 6.3 44.2 7.3 5.8 44.2 1.1 1 0 0 1 1 1 0 BUD22 IPK PF03770.16 VBB30167.1 - 7.6e-32 110.8 2.3 1.2e-31 110.1 0.4 2.3 2 1 0 2 2 2 1 Inositol polyphosphate kinase Ribosomal_S3_C PF00189.20 VBB30168.1 - 1.9e-23 82.8 1.0 2.4e-23 82.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Pkinase_Tyr PF07714.17 VBB30169.1 - 4e-76 255.7 0.0 5.3e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30169.1 - 7.4e-46 156.6 0.0 1e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 VBB30169.1 - 1.9e-08 34.3 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 VBB30169.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB30169.1 - 0.063 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF5093 PF17011.5 VBB30169.1 - 0.068 13.5 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) MFS_1 PF07690.16 VBB30170.1 - 9.6e-44 149.7 55.8 3.4e-43 147.9 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.6 VBB30171.1 - 8.4e-18 64.5 5.5 1.7e-09 37.9 0.1 5.6 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 VBB30171.1 - 5.1e-12 45.3 0.9 0.0014 18.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB30171.1 - 0.0013 18.6 0.1 8 6.7 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB30171.1 - 0.0016 18.5 6.6 0.65 10.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB30171.1 - 0.003 17.3 3.9 1.7 8.6 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB30171.1 - 0.11 12.6 12.1 13 6.2 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat adh_short PF00106.25 VBB30172.1 - 5.4e-24 84.7 0.1 8.1e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB30172.1 - 3.6e-16 59.4 0.0 4.7e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB30172.1 - 0.00071 19.5 0.8 0.0014 18.6 0.2 1.8 2 1 0 2 2 2 1 KR domain Pkinase PF00069.25 VBB30174.1 - 2.4e-68 230.4 0.0 5.2e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30174.1 - 1.1e-29 103.5 0.0 4.1e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB30174.1 - 1.6e-08 33.8 0.2 1.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 VBB30174.1 - 0.00015 21.2 0.0 0.00035 20.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB30174.1 - 0.0075 15.6 0.0 0.024 14.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like NPL4 PF05021.15 VBB30174.1 - 0.13 11.6 0.3 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 NPL4 family FHA PF00498.26 VBB30175.1 - 3.2e-13 49.8 0.2 7.3e-13 48.7 0.2 1.7 1 0 0 1 1 1 1 FHA domain PHD PF00628.29 VBB30175.1 - 0.034 14.0 10.7 0.078 12.9 10.7 1.6 1 0 0 1 1 1 0 PHD-finger Dam PF05869.11 VBB30175.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) TFIIA PF03153.13 VBB30176.1 - 0.25 11.3 37.9 0.18 11.7 5.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CAP_N PF01213.19 VBB30177.1 - 0.07 12.6 2.1 0.075 12.5 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 VBB30177.1 - 0.26 11.4 0.1 0.21 11.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 VBB30177.1 - 0.44 10.6 3.9 0.59 10.2 3.9 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RCDG1 PF15725.5 VBB30177.1 - 7.1 7.1 10.6 6.8 7.2 8.3 1.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Alg6_Alg8 PF03155.15 VBB30178.1 - 9.5e-96 321.7 22.8 8.5e-56 189.9 11.3 2.2 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family NTP_transferase PF00483.23 VBB30178.1 - 1.2e-49 169.2 0.0 2.2e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase INCENP_ARK-bind PF03941.15 VBB30178.1 - 1.6e-17 63.2 0.3 4.1e-17 61.9 0.3 1.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Hexapep PF00132.24 VBB30178.1 - 5e-11 41.9 20.8 1.8e-06 27.5 3.9 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 VBB30178.1 - 1.5e-08 35.2 0.0 2.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 VBB30178.1 - 0.00051 19.7 19.1 0.0083 15.9 4.6 3.7 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF5114 PF17141.4 VBB30178.1 - 0.029 14.9 0.6 0.13 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5114) IspD PF01128.19 VBB30178.1 - 0.072 12.8 0.6 1.5 8.5 0.0 2.9 3 1 1 4 4 4 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase His_Phos_1 PF00300.22 VBB30182.1 - 2.4e-10 40.5 0.0 8e-10 38.7 0.0 1.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1840 PF08895.11 VBB30182.1 - 0.043 14.1 0.3 0.089 13.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) A2M PF00207.22 VBB30183.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin family AMP-binding PF00501.28 VBB30184.1 - 3.7e-77 259.7 0.0 1.6e-58 198.3 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 VBB30184.1 - 1.2e-10 42.2 0.0 3e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP-synt_F PF01990.17 VBB30184.1 - 0.02 15.2 0.1 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Translin PF01997.16 VBB30185.1 - 1.1e-47 162.7 2.5 1.1e-47 162.7 2.5 2.0 2 0 0 2 2 2 1 Translin family Cgr1 PF03879.14 VBB30185.1 - 5.7e-09 36.3 25.9 5.7e-09 36.3 25.9 3.3 3 1 0 3 3 3 1 Cgr1 family DUF3512 PF12024.8 VBB30185.1 - 1.3 8.4 7.4 0.25 10.8 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) OSCP PF00213.18 VBB30186.1 - 8.7e-13 48.7 0.3 1.1e-12 48.5 0.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Hydrolase_3 PF08282.12 VBB30186.1 - 0.0036 17.1 0.1 0.0036 17.1 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Macro_2 PF14519.6 VBB30186.1 - 0.065 12.6 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 Macro-like domain HTH_Tnp_ISL3 PF13542.6 VBB30186.1 - 0.084 12.3 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 ThrE PF06738.12 VBB30187.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter OSCP PF00213.18 VBB30188.1 - 4.9e-18 65.8 0.1 5.3e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit FAA_hydrolase_N PF09298.11 VBB30188.1 - 0.044 14.0 0.2 10 6.4 0.0 2.1 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal Jiraiya PF15038.6 VBB30189.1 - 9.9e-39 132.5 14.4 1.2e-38 132.2 14.4 1.1 1 0 0 1 1 1 1 Jiraiya UPF0182 PF03699.13 VBB30189.1 - 0.073 11.2 2.7 0.093 10.9 2.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) UPF0640 PF15114.6 VBB30189.1 - 0.087 12.6 0.5 0.22 11.3 0.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 Bac_export_2 PF01312.19 VBB30189.1 - 1.7 7.8 10.6 2.1 7.5 10.6 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family RRM_1 PF00076.22 VBB30190.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0160 PF03690.13 VBB30191.1 - 4.3e-96 322.3 0.2 3.8e-53 181.2 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0160) Sprouty PF05210.13 VBB30193.1 - 8.2e-19 67.9 3.9 1.7e-18 66.9 3.9 1.5 1 0 0 1 1 1 1 Sprouty protein (Spry) zf-C2HE PF16278.5 VBB30193.1 - 0.032 14.7 1.8 0.094 13.2 0.2 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger IL1_propep PF02394.16 VBB30193.1 - 0.13 13.2 0.3 0.27 12.2 0.3 1.5 1 0 0 1 1 1 0 Interleukin-1 propeptide PUF PF00806.19 VBB30196.1 - 9.4e-68 220.3 12.7 1.8e-09 36.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 VBB30196.1 - 0.0041 17.5 7.6 1 9.7 0.1 4.8 2 1 2 5 5 5 1 CPL (NUC119) domain DUF445 PF04286.12 VBB30196.1 - 0.0052 16.6 1.3 0.49 10.2 0.2 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF445) PLN_propep PF16485.5 VBB30196.1 - 0.0089 15.7 1.0 0.64 9.8 0.2 2.8 1 1 1 2 2 2 1 Protealysin propeptide sCache_2 PF17200.4 VBB30196.1 - 0.012 15.4 2.1 0.9 9.4 0.0 4.0 4 1 1 5 5 5 0 Single Cache domain 2 TEX33 PF15400.6 VBB30196.1 - 0.12 12.8 0.6 55 4.3 0.0 3.5 3 2 0 4 4 4 0 Testis-expressed sequence 33 protein family DUF577 PF04510.12 VBB30196.1 - 0.42 10.5 2.0 0.5 10.2 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF577) LMBR1 PF04791.16 VBB30197.1 - 0.011 14.7 3.1 0.014 14.4 3.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3585 PF12130.8 VBB30198.1 - 8.6e-10 38.9 20.0 4.2e-09 36.7 20.0 2.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain FAD_binding_2 PF00890.24 VBB30198.1 - 0.00027 20.1 0.1 0.00053 19.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 VBB30198.1 - 0.0003 20.1 0.0 0.00091 18.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CH PF00307.31 VBB30198.1 - 0.00045 20.4 0.0 0.0027 17.9 0.0 2.4 2 0 0 2 2 1 1 Calponin homology (CH) domain FAD_binding_3 PF01494.19 VBB30198.1 - 0.00088 18.6 0.0 0.0033 16.7 0.0 2.0 1 0 0 1 1 1 1 FAD binding domain LIM PF00412.22 VBB30198.1 - 0.0025 18.0 5.8 0.0025 18.0 5.8 2.1 2 0 0 2 2 1 1 LIM domain Pyr_redox_3 PF13738.6 VBB30198.1 - 0.0025 17.1 0.0 0.0082 15.4 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 VBB30198.1 - 0.0051 16.2 0.1 0.015 14.6 0.1 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 VBB30198.1 - 0.014 15.9 0.1 0.12 12.9 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 VBB30198.1 - 0.018 13.7 0.0 0.018 13.7 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 VBB30198.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase CAMSAP_CH PF11971.8 VBB30198.1 - 0.089 12.6 0.0 0.37 10.7 0.0 2.1 1 0 0 1 1 1 0 CAMSAP CH domain GIDA PF01134.22 VBB30198.1 - 0.1 11.7 1.5 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A PPR_3 PF13812.6 VBB30200.1 - 0.015 15.4 0.1 1.3 9.2 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain ATP13 PF12921.7 VBB30200.1 - 0.12 12.2 0.4 7 6.5 0.0 3.6 3 1 1 4 4 4 0 Mitochondrial ATPase expression PMBR PF09373.10 VBB30200.1 - 0.19 11.9 2.0 7.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat STPPase_N PF16891.5 VBB30202.1 - 0.00038 20.8 0.3 0.00066 20.1 0.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 VBB30202.1 - 0.0017 18.9 0.1 0.015 15.8 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Dehydratase_SU PF02287.15 VBB30203.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Dehydratase small subunit MNE1 PF13762.6 VBB30203.1 - 0.12 12.4 1.5 9.5 6.2 0.1 2.8 1 1 2 3 3 3 0 Mitochondrial splicing apparatus component PAN_1 PF00024.26 VBB30204.1 - 2e-12 46.9 10.6 1.8e-08 34.2 0.5 3.2 3 0 0 3 3 3 2 PAN domain Interfer-bind PF09294.10 VBB30205.1 - 0.067 13.5 0.1 0.082 13.2 0.1 1.1 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DUF5113 PF17140.4 VBB30205.1 - 0.21 11.4 0.1 0.32 10.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5113) Lipase_2 PF01674.18 VBB30206.1 - 0.0079 15.7 0.2 0.0091 15.5 0.2 1.1 1 0 0 1 1 1 1 Lipase (class 2) zf-C4pol PF14260.6 VBB30206.1 - 0.099 13.1 0.4 0.28 11.7 0.2 1.7 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF1548 PF07579.11 VBB30207.1 - 0.029 14.7 0.5 0.2 12.0 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) Surp PF01805.20 VBB30208.1 - 9.5e-19 67.1 1.3 1.3e-11 44.3 0.1 3.0 3 0 0 3 3 3 2 Surp module DRY_EERY PF09750.9 VBB30208.1 - 1.2e-17 64.4 2.9 1.2e-17 64.4 2.9 4.0 4 0 0 4 4 4 1 Alternative splicing regulator DNA_pol_E_B PF04042.16 VBB30209.1 - 2.3e-32 112.1 0.6 3.4e-32 111.5 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Actin PF00022.19 VBB30209.1 - 0.00017 20.3 0.6 0.0003 19.5 0.6 1.3 1 0 0 1 1 1 1 Actin ATG101 PF07855.12 VBB30210.1 - 0.005 16.8 0.0 0.22 11.5 0.0 2.2 1 1 0 1 1 1 1 Autophagy-related protein 101 PI3_PI4_kinase PF00454.27 VBB30211.1 - 3.2e-40 138.5 0.0 1.6e-39 136.2 0.0 2.2 1 1 1 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 VBB30211.1 - 4.9e-23 81.9 4.2 6.2e-22 78.3 3.7 2.7 3 0 0 3 3 3 1 FAT domain FATC PF02260.20 VBB30211.1 - 5.4e-12 45.3 0.0 1.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 FATC domain UME PF08064.13 VBB30211.1 - 5.1e-05 23.1 0.1 0.00041 20.2 0.1 2.8 1 0 0 1 1 1 1 UME (NUC010) domain DUF3385 PF11865.8 VBB30211.1 - 0.018 15.0 0.1 0.4 10.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) CTD_bind PF04818.13 VBB30211.1 - 0.15 12.9 1.7 7 7.6 0.0 3.9 5 0 0 5 5 5 0 RNA polymerase II-binding domain. DUF1477 PF07346.11 VBB30211.1 - 2.1 8.6 5.2 9.3 6.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1477) TMEM189_B_dmain PF10520.9 VBB30214.1 - 4.6e-53 179.9 5.3 5.2e-53 179.7 5.3 1.0 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain SNF2_N PF00176.23 VBB30216.1 - 5e-63 212.9 1.0 1.1e-62 211.8 1.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain BRK PF07533.16 VBB30216.1 - 1.1e-27 95.3 0.1 4.5e-15 55.0 0.1 2.8 2 0 0 2 2 2 2 BRK domain Helicase_C PF00271.31 VBB30216.1 - 4.2e-19 68.9 0.1 4e-18 65.8 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 VBB30216.1 - 6.8e-17 61.1 4.8 8.9e-09 35.1 1.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 VBB30216.1 - 0.0011 19.2 0.7 2.2 8.5 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain UQ_con PF00179.26 VBB30217.1 - 1.3e-18 67.0 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 VBB30217.1 - 0.07 13.4 0.0 0.088 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 VBB30218.1 - 1.2e-19 70.3 21.3 9.8e-07 29.4 0.2 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Bromodomain PF00439.25 VBB30218.1 - 1.8e-18 66.4 0.4 1.5e-15 57.0 0.2 2.6 2 0 0 2 2 2 2 Bromodomain Auxin_resp PF06507.13 VBB30218.1 - 4.1e-07 30.2 0.0 2.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Auxin response factor ANAPC4_WD40 PF12894.7 VBB30218.1 - 1.6e-06 28.3 0.3 3.2 8.1 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 VBB30218.1 - 0.0051 16.8 0.0 0.082 12.9 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat PilZ_2 PF16823.5 VBB30218.1 - 0.054 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor UL17 PF17640.2 VBB30218.1 - 0.55 10.3 3.5 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized UL17 BBIP10 PF14777.6 VBB30219.1 - 9.8e-19 66.7 3.6 1.6e-18 66.1 3.6 1.3 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 GreA_GreB_N PF03449.15 VBB30219.1 - 0.0042 17.2 3.4 0.007 16.5 3.4 1.4 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal WRNPLPNID PF15017.6 VBB30219.1 - 0.77 10.7 4.5 0.29 12.0 1.8 1.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Ribosomal_S6 PF01250.17 VBB30220.1 - 8.9e-08 32.3 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 TMEM52 PF14979.6 VBB30221.1 - 0.021 14.7 2.7 0.028 14.3 1.2 1.7 1 1 1 2 2 2 0 Transmembrane 52 Metallophos PF00149.28 VBB30222.1 - 1.3e-29 104.2 0.0 1.8e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Engrail_1_C_sig PF10525.9 VBB30222.1 - 0.14 11.4 0.3 0.28 10.4 0.3 1.4 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Far-17a_AIG1 PF04750.14 VBB30223.1 - 9.7e-31 106.7 10.6 1.1e-30 106.5 10.6 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Sec7 PF01369.20 VBB30225.1 - 1.7e-59 200.6 0.0 2.4e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 VBB30225.1 - 6.2e-51 172.0 0.2 1e-50 171.3 0.2 1.3 1 0 0 1 1 1 1 PH domain Mog1 PF04603.12 VBB30225.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Ran-interacting Mog1 protein PH_13 PF16652.5 VBB30225.1 - 0.15 11.9 0.0 0.33 10.7 0.0 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain SAPIS-gp6 PF16722.5 VBB30226.1 - 0.017 15.5 0.8 0.024 15.0 0.8 1.3 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Uso1_p115_head PF04869.14 VBB30227.1 - 1.5e-53 182.0 0.7 3.2e-51 174.3 0.1 2.6 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 VBB30227.1 - 2.7e-17 62.4 2.1 3.1e-16 59.0 1.1 2.8 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 VBB30227.1 - 1.3e-11 44.9 9.2 1.3e-11 44.9 9.2 2.7 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Mo25 PF08569.11 VBB30227.1 - 8e-05 22.2 1.1 8e-05 22.2 1.1 3.4 1 1 1 3 3 3 1 Mo25-like Atx10homo_assoc PF09759.9 VBB30227.1 - 0.0011 19.0 0.8 0.012 15.7 0.4 2.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 VBB30227.1 - 0.01 15.9 12.3 0.014 15.4 1.1 4.2 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF3972 PF13118.6 VBB30227.1 - 0.12 12.8 7.3 0.025 15.0 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DUF2621 PF11084.8 VBB30227.1 - 0.13 12.3 2.2 0.42 10.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2621) DLH PF01738.18 VBB30227.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1351 PF07083.11 VBB30227.1 - 0.18 11.6 15.3 0.093 12.5 12.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) SepSecS PF05889.13 VBB30227.1 - 0.23 10.1 2.2 0.22 10.2 0.7 1.7 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3636 PF12331.8 VBB30227.1 - 0.31 10.9 4.3 0.32 10.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) SPK PF04435.18 VBB30227.1 - 0.96 9.9 3.9 0.79 10.2 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF545) DUF3361 PF11841.8 VBB30227.1 - 1 9.3 10.6 0.033 14.1 1.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) TFR_dimer PF04253.15 VBB30227.1 - 6.8 6.8 7.8 24 5.0 1.7 2.6 1 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain Myosin_head PF00063.21 VBB30228.1 - 2.4e-90 303.7 0.0 2.4e-90 303.7 0.0 2.7 2 1 0 2 2 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 VBB30228.1 - 4.8e-08 31.3 62.7 4.8e-08 31.3 62.7 3.1 1 1 2 3 3 3 1 Myosin tail PDZ_6 PF17820.1 VBB30228.1 - 0.00021 21.1 0.0 0.00061 19.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain LEF-8 PF04941.12 VBB30228.1 - 0.00054 18.4 0.0 0.00097 17.5 0.0 1.3 1 0 0 1 1 1 1 Late expression factor 8 (LEF-8) AAA_16 PF13191.6 VBB30228.1 - 0.01 16.2 0.0 0.01 16.2 0.0 5.6 2 2 1 5 5 4 0 AAA ATPase domain PDZ PF00595.24 VBB30228.1 - 0.04 14.3 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PDZ_2 PF13180.6 VBB30228.1 - 0.095 13.0 0.1 3.2 8.1 0.0 3.2 2 0 0 2 2 2 0 PDZ domain AAA_22 PF13401.6 VBB30228.1 - 0.1 12.9 0.0 0.1 12.9 0.0 4.3 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 VBB30228.1 - 0.58 10.5 0.0 0.58 10.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain GBR2_CC PF18455.1 VBB30228.1 - 4.1 7.6 7.0 8.9 6.5 0.1 4.0 3 0 0 3 3 3 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain PspB PF06667.12 VBB30228.1 - 9.6 6.4 12.9 17 5.6 3.3 4.0 2 0 0 2 2 2 0 Phage shock protein B Piwi PF02171.17 VBB30229.1 - 2.7e-107 358.5 0.1 3.7e-107 358.0 0.1 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 VBB30229.1 - 3.8e-13 49.4 0.0 7.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 VBB30229.1 - 1.5e-10 40.5 0.0 3.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 VBB30229.1 - 2.6e-09 37.2 0.0 5.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 VBB30229.1 - 6.9e-09 35.9 0.0 2.5e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain Cation_efflux PF01545.21 VBB30230.1 - 1.6e-49 168.3 13.1 2e-49 168.0 13.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4212 PF13937.6 VBB30230.1 - 0.39 11.1 3.0 7.8 7.0 3.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4212) FXa_inhibition PF14670.6 VBB30232.1 - 0.17 12.2 1.6 0.3 11.4 1.6 1.4 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site START PF01852.19 VBB30233.1 - 1.3e-29 103.1 0.6 2e-29 102.5 0.6 1.3 1 0 0 1 1 1 1 START domain PH PF00169.29 VBB30233.1 - 3e-10 40.5 0.3 8.2e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 VBB30233.1 - 2.3e-05 24.6 2.9 2.3e-05 24.6 0.5 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 VBB30233.1 - 0.0011 19.3 7.6 0.01 16.3 7.6 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PapD_N PF00345.20 VBB30233.1 - 0.13 12.1 0.3 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Las1 PF04031.13 VBB30234.1 - 5.7e-09 36.3 0.0 6.6e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Las1-like Imm26 PF15428.6 VBB30234.1 - 0.002 18.3 0.0 0.098 12.9 0.0 2.1 2 0 0 2 2 2 2 Immunity protein 26 QVR PF17064.5 VBB30235.1 - 7.2 6.9 11.9 34 4.8 11.9 2.1 1 1 0 1 1 1 0 Sleepless protein Acetyltransf_13 PF13880.6 VBB30236.1 - 1.1e-19 70.1 0.3 2.6e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 VBB30236.1 - 3.7e-15 55.4 6.3 8e-15 54.4 6.3 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 VBB30236.1 - 0.0065 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB30236.1 - 0.076 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RRM_1 PF00076.22 VBB30237.1 - 8.9e-16 57.5 0.0 4.7e-15 55.2 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 VBB30237.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif THRAP3_BCLAF1 PF15440.6 VBB30237.1 - 4.3 6.2 38.0 6.4 5.7 38.0 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family FAM76 PF16046.5 VBB30237.1 - 7.9 5.7 16.8 12 5.2 16.8 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4187 PF13821.6 VBB30238.1 - 8.3e-18 63.9 3.3 2.1e-17 62.6 3.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 VBB30238.1 - 3.6e-10 39.6 0.2 7e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 G-patch domain DUF5561 PF17716.1 VBB30238.1 - 0.001 18.4 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5561) CwfJ_C_1 PF04677.15 VBB30239.1 - 4.7e-37 126.6 0.1 8.2e-37 125.8 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 VBB30239.1 - 3.4e-14 53.5 0.1 2.2e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Phosducin PF02114.16 VBB30239.1 - 0.12 11.2 0.9 0.27 10.2 0.9 1.5 1 0 0 1 1 1 0 Phosducin PAX PF00292.18 VBB30241.1 - 4.4e-47 159.1 1.2 6.3e-47 158.6 1.2 1.2 1 0 0 1 1 1 1 'Paired box' domain DUF3742 PF12553.8 VBB30241.1 - 3.5e-06 27.1 5.3 0.0027 17.8 3.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3742) HTH_23 PF13384.6 VBB30241.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 VBB30241.1 - 0.00066 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix MarR_2 PF12802.7 VBB30241.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_Tnp_IS1 PF12759.7 VBB30241.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 InsA C-terminal domain EphA2_TM PF14575.6 VBB30241.1 - 0.065 14.1 17.1 0.21 12.5 2.4 3.3 2 1 1 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 VBB30241.1 - 0.13 13.0 8.6 3.8 8.3 0.0 2.8 2 1 1 3 3 3 0 Cadherin cytoplasmic C-terminal gpUL132 PF11359.8 VBB30241.1 - 0.29 10.6 5.1 0.35 10.4 0.7 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 TMEM154 PF15102.6 VBB30241.1 - 0.63 9.9 16.6 36 4.2 0.0 2.8 2 1 0 2 2 2 0 TMEM154 protein family GPI2 PF06432.11 VBB30241.1 - 1.4 8.3 8.8 0.71 9.3 5.7 1.8 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Tmemb_9 PF05434.11 VBB30242.1 - 3e-44 150.4 7.8 4.9e-43 146.5 7.8 2.0 1 1 0 1 1 1 1 TMEM9 Shisa PF13908.6 VBB30242.1 - 0.0023 18.2 0.1 0.0031 17.8 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 VBB30242.1 - 0.013 15.1 2.2 0.013 15.1 2.2 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Tenui_PVC2 PF06656.11 VBB30242.1 - 0.013 13.4 1.2 0.017 13.1 1.2 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein COX2_TM PF02790.15 VBB30242.1 - 0.04 14.1 0.3 0.085 13.0 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF5527 PF17665.1 VBB30242.1 - 0.057 12.9 0.3 0.078 12.5 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Orf78 PF06024.12 VBB30242.1 - 0.061 13.6 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Gemini_mov PF01708.16 VBB30242.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein AA_permease PF00324.21 VBB30243.1 - 1.5e-50 172.2 38.0 4e-36 124.6 6.3 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 VBB30243.1 - 1.9e-29 103.0 2.9 4.7e-23 81.9 0.7 2.2 1 1 1 2 2 2 2 Solute carrier family 12 MFS_1 PF07690.16 VBB30244.1 - 1.3e-44 152.6 32.0 4.3e-43 147.6 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WBS_methylT PF12589.8 VBB30244.1 - 0.51 11.1 2.9 0.87 10.4 2.9 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome GTP_EFTU PF00009.27 VBB30245.1 - 1.4e-40 138.9 0.0 2.7e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 VBB30245.1 - 2.6e-38 131.4 10.5 5.1e-38 130.4 10.5 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 VBB30245.1 - 9.8e-24 83.2 0.0 3.2e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 VBB30245.1 - 4.3e-22 78.2 0.0 9.6e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 VBB30245.1 - 1.5e-12 47.7 0.0 2.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 VBB30245.1 - 2.8e-06 27.3 0.1 1.1e-05 25.4 0.1 2.1 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 VBB30245.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB30245.1 - 0.024 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Ras family CHGN PF05679.16 VBB30246.1 - 7.4e-106 355.0 0.0 9.4e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase zf-RING_2 PF13639.6 VBB30247.1 - 0.098 13.0 0.1 0.32 11.4 0.1 2.0 1 0 0 1 1 1 0 Ring finger domain Glyco_hydro_47 PF01532.20 VBB30249.1 - 1.6e-38 132.8 0.0 2.2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 tRNA-synt_2 PF00152.20 VBB30250.1 - 2e-54 184.8 0.4 3.4e-54 184.0 0.4 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 VBB30250.1 - 7.1e-05 22.7 0.1 0.0002 21.2 0.1 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 VBB30250.1 - 0.025 14.1 0.2 0.12 11.8 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 VBB30251.1 - 1.7e-31 109.5 0.0 2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) C_tripleX PF02363.19 VBB30253.1 - 0.00019 21.4 212.1 0.11 12.8 0.6 17.3 14 2 1 15 15 15 12 Cysteine rich repeat TMEM154 PF15102.6 VBB30254.1 - 0.00086 19.2 0.4 0.00086 19.2 0.4 2.2 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.8 VBB30254.1 - 0.0024 17.7 2.5 0.0057 16.6 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) UL41A PF17591.2 VBB30254.1 - 0.023 14.8 1.9 0.1 12.7 0.3 2.3 2 0 0 2 2 2 0 Herpesvirus UL41A DUF2207 PF09972.9 VBB30254.1 - 0.029 13.1 0.1 0.045 12.5 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Na_Ala_symp PF01235.17 VBB30254.1 - 0.043 13.1 0.2 0.06 12.6 0.2 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family F-box-like PF12937.7 VBB30255.1 - 0.0034 17.2 0.9 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 VBB30255.1 - 0.015 15.1 1.2 0.13 12.1 0.2 3.0 3 0 0 3 3 3 0 F-box domain Pox_D5 PF03288.16 VBB30255.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like Arylesterase PF01731.20 VBB30256.1 - 1.2e-16 60.6 2.6 3.2e-16 59.3 0.4 2.6 3 0 0 3 3 3 1 Arylesterase SGL PF08450.12 VBB30256.1 - 3.3e-05 23.6 0.0 7.4e-05 22.5 0.0 1.5 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 VBB30256.1 - 0.00069 19.5 0.0 0.28 11.3 0.0 3.5 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.16 VBB30256.1 - 0.11 12.7 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase zf-H2C2_2 PF13465.6 VBB30257.1 - 4.7e-19 67.9 16.4 9.3e-09 35.3 1.3 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 VBB30257.1 - 3.6e-18 64.9 28.5 1.5e-05 25.2 4.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB30257.1 - 2.6e-13 49.6 24.0 0.0028 18.3 1.3 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 VBB30257.1 - 8.6e-06 25.4 0.5 8.6e-06 25.4 0.5 3.7 4 0 0 4 4 3 2 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 VBB30257.1 - 0.0031 17.6 9.1 0.022 14.9 1.7 3.6 3 0 0 3 3 3 1 Zinc ribbon domain zf-Di19 PF05605.12 VBB30257.1 - 0.0035 17.6 11.9 0.25 11.7 2.9 3.4 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 VBB30257.1 - 0.0057 16.3 8.9 0.61 9.8 0.1 4.6 2 1 2 4 4 4 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 VBB30257.1 - 0.0093 16.6 2.8 0.037 14.7 2.8 2.1 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 VBB30257.1 - 0.012 15.6 0.7 6.2 6.9 0.0 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 VBB30257.1 - 0.017 15.1 1.1 0.017 15.1 1.1 4.5 5 0 0 5 5 4 0 C2H2-type zinc finger DUF2225 PF09986.9 VBB30257.1 - 0.018 14.8 1.5 0.063 13.0 1.5 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 VBB30257.1 - 0.14 12.9 7.2 1.9 9.3 0.9 2.8 1 1 1 2 2 2 0 zinc-ribbon family zf_UBZ PF18439.1 VBB30257.1 - 0.2 11.3 7.8 6.7 6.4 0.0 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 VBB30257.1 - 0.43 11.0 5.2 9 6.8 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3268 PF11672.8 VBB30257.1 - 0.45 10.9 3.7 1.9 8.8 0.7 2.5 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 VBB30257.1 - 0.45 10.9 0.1 0.45 10.9 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 VBB30257.1 - 0.5 10.3 13.6 6.1 6.8 0.1 4.2 2 1 0 3 3 3 0 SprT-like zinc ribbon domain DZR PF12773.7 VBB30257.1 - 0.51 10.4 9.5 0.28 11.2 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 VBB30257.1 - 0.64 10.2 9.8 1.1 9.4 5.7 2.7 2 0 0 2 2 2 0 FYVE zinc finger Kp4 PF09044.10 VBB30257.1 - 3.7 7.6 5.2 25 5.0 1.7 2.8 3 1 0 3 3 2 0 Kp4 DEP PF00610.21 VBB30258.1 - 9.9e-09 35.1 0.0 3.2e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 VBB30258.1 - 0.036 13.9 0.5 0.22 11.3 0.2 2.3 2 0 0 2 2 2 0 RhoGAP domain TetR_C_32 PF09209.11 VBB30258.1 - 0.039 13.9 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF148 PF02520.17 VBB30258.1 - 0.063 13.4 1.1 0.17 12.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF148 Chlam_OMP3 PF03503.13 VBB30258.1 - 0.17 12.2 0.0 0.47 10.8 0.0 1.7 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 STN1_2 PF09170.10 VBB30258.1 - 0.45 10.7 3.4 0.38 10.9 0.8 2.1 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Paf67 PF10255.9 VBB30259.1 - 3.1e-139 464.5 1.9 4e-139 464.1 1.9 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.27 VBB30259.1 - 0.051 14.1 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 PCI domain Rer1 PF03248.13 VBB30260.1 - 9.2e-73 243.6 10.4 1.1e-72 243.4 10.4 1.0 1 0 0 1 1 1 1 Rer1 family WD40 PF00400.32 VBB30261.1 - 2.1e-22 79.0 2.4 2.2e-07 31.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30261.1 - 8.9e-05 22.7 0.0 14 6.1 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 VBB30261.1 - 0.001 18.4 0.0 0.0058 15.9 0.0 2.1 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller UAA PF08449.11 VBB30263.1 - 9.7e-46 156.3 8.3 1.1e-45 156.2 8.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 VBB30263.1 - 6.3e-05 22.5 1.2 7e-05 22.3 1.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 VBB30263.1 - 0.043 14.0 9.8 0.064 13.4 9.8 1.5 1 1 0 1 1 1 0 EamA-like transporter family TMEM234 PF10639.9 VBB30263.1 - 0.055 13.5 3.0 0.079 13.0 2.7 1.3 1 1 0 1 1 1 0 Putative transmembrane family 234 DUF2070 PF09843.9 VBB30263.1 - 1.6 6.9 6.1 1.6 6.9 6.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Secretogranin_V PF05281.11 VBB30264.1 - 1.6e-35 122.8 0.2 2.2e-35 122.3 0.2 1.2 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) PI3_PI4_kinase PF00454.27 VBB30266.1 - 3e-32 112.4 0.0 4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Dopey_N PF04118.14 VBB30267.1 - 2e-94 316.2 0.0 2e-94 316.2 0.0 3.2 4 0 0 4 4 4 1 Dopey, N-terminal PH PF00169.29 VBB30268.1 - 2.2e-05 24.9 0.2 5.6e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 PH domain Collagen PF01391.18 VBB30269.1 - 3.7e-28 97.1 102.3 4.1e-10 39.3 30.9 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB30269.1 - 2.6e-07 30.6 0.1 3.5e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Isochorismatase PF00857.20 VBB30271.1 - 2.8e-30 105.8 0.1 5e-30 105.0 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family Neur_chan_LBD PF02931.23 VBB30273.1 - 9.6e-24 84.0 1.4 1.1e-23 83.8 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ANAPC1 PF12859.7 VBB30275.1 - 0.067 13.7 8.4 0.12 12.9 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 VBB30275.1 - 5.1 7.7 13.2 14 6.4 0.3 5.0 5 0 0 5 5 5 0 Proteasome/cyclosome repeat BRO1 PF03097.18 VBB30277.1 - 0.065 12.0 0.1 0.077 11.8 0.1 1.1 1 0 0 1 1 1 0 BRO1-like domain LRR_4 PF12799.7 VBB30279.1 - 2.8e-06 27.5 4.3 0.39 11.2 0.0 5.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) GCS PF03074.16 VBB30280.1 - 6.3e-168 558.8 0.0 7.6e-168 558.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase ShK PF01549.24 VBB30281.1 - 1.7e-18 66.9 37.3 2.2e-07 31.3 6.0 3.3 3 0 0 3 3 3 3 ShK domain-like BUD22 PF09073.10 VBB30281.1 - 0.014 14.8 4.0 0.016 14.6 4.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 VBB30281.1 - 0.15 11.5 8.9 0.18 11.2 8.9 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 VBB30281.1 - 0.43 9.7 7.6 0.68 9.1 7.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 VBB30281.1 - 0.74 10.1 6.6 1.1 9.5 6.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 VBB30281.1 - 1.4 7.0 10.4 1.9 6.5 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi I-set PF07679.16 VBB30282.1 - 3e-18 65.7 0.0 7.8e-17 61.1 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB30282.1 - 1.7e-17 63.8 0.0 3.6e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 VBB30282.1 - 1.7e-15 57.1 0.0 7.3e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 VBB30282.1 - 2.1e-10 40.6 0.0 4e-08 33.3 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 VBB30282.1 - 1.8e-08 34.5 0.1 0.018 15.2 0.0 3.4 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB30282.1 - 3.5e-06 27.3 0.0 3.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 VBB30282.1 - 4.1e-05 23.6 0.0 8.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 VBB30282.1 - 0.00011 22.4 0.0 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 VBB30282.1 - 0.0051 17.2 0.1 0.039 14.3 0.1 2.4 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 VBB30282.1 - 0.015 15.4 0.0 5.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Comm PF15957.5 VBB30282.1 - 0.027 14.8 1.8 0.042 14.2 0.0 2.1 2 1 0 2 2 2 0 Commissureless Ig_6 PF18452.1 VBB30282.1 - 0.036 13.6 0.0 0.65 9.6 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain DUF2207 PF09972.9 VBB30282.1 - 0.06 12.1 0.1 0.075 11.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5058 PF16481.5 VBB30282.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) LRR19-TM PF15176.6 VBB30282.1 - 0.076 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SIT PF15330.6 VBB30282.1 - 0.077 13.4 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT HemY_N PF07219.13 VBB30282.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 HemY protein N-terminus TadE PF07811.12 VBB30282.1 - 0.17 12.2 0.6 0.37 11.1 0.6 1.6 1 0 0 1 1 1 0 TadE-like protein TRI12 PF06609.13 VBB30282.1 - 0.21 10.0 0.6 0.31 9.4 0.6 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF4083 PF13314.6 VBB30282.1 - 0.78 9.7 3.9 1.7 8.6 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ADP_ribosyl_GH PF03747.14 VBB30284.1 - 1.3e-43 149.9 0.0 1.5e-43 149.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 VBB30284.1 - 0.082 12.8 1.3 0.23 11.4 1.3 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain MCM2_N PF12619.8 VBB30285.1 - 0.53 10.6 5.7 0.71 10.2 4.8 1.7 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 Peptidase_C12 PF01088.21 VBB30286.1 - 1e-42 146.3 0.0 2.8e-42 144.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Thioredoxin PF00085.20 VBB30286.1 - 1.4e-16 60.4 0.0 4.9e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin FAM176 PF14851.6 VBB30286.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 VBB30286.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter OST3_OST6 PF04756.13 VBB30286.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF997 PF06196.12 VBB30286.1 - 0.15 12.1 1.4 0.42 10.6 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF997) KH_1 PF00013.29 VBB30287.1 - 6e-07 29.2 0.1 1.3e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 KH domain DUF1704 PF08014.11 VBB30288.1 - 0.016 14.2 2.0 0.021 13.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) UPF0054 PF02130.17 VBB30288.1 - 0.024 14.4 0.2 0.048 13.5 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 DUF4407 PF14362.6 VBB30288.1 - 0.048 13.0 4.1 0.055 12.8 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G_path_suppress PF15991.5 VBB30288.1 - 0.11 12.7 7.4 0.13 12.4 7.4 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor HOIP-UBA PF16678.5 VBB30288.1 - 0.16 12.0 6.3 0.29 11.2 6.3 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Jnk-SapK_ap_N PF09744.9 VBB30288.1 - 0.25 11.6 10.7 0.41 10.9 10.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 VBB30288.1 - 0.68 7.8 6.9 0.83 7.5 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Transglut_i_TM PF14400.6 VBB30288.1 - 0.84 9.7 5.4 1.4 9.0 5.4 1.3 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices DUF5383 PF17355.2 VBB30288.1 - 3 8.2 7.0 4.8 7.6 7.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Fra10Ac1 PF09725.9 VBB30289.1 - 2.5e-41 140.7 6.8 6.6e-41 139.3 6.8 1.8 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 ICMT PF04140.14 VBB30289.1 - 1.3e-19 70.4 1.0 4.8e-19 68.6 0.1 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 VBB30289.1 - 1.9e-06 28.2 0.2 7.4e-06 26.3 0.2 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF3525 PF12039.8 VBB30289.1 - 0.082 11.6 0.8 0.13 11.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Pinin_SDK_memA PF04696.13 VBB30289.1 - 7.5 6.6 13.4 1.4 9.0 8.9 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region KH_1 PF00013.29 VBB30290.1 - 3e-166 539.5 43.0 3e-16 59.0 1.3 15.3 15 0 0 15 15 15 15 KH domain SLS PF14611.6 VBB30290.1 - 5.4e-20 72.2 17.0 0.017 15.0 1.9 8.7 3 2 4 8 8 8 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 VBB30290.1 - 1.9e-15 56.5 19.3 0.0039 17.0 0.4 9.5 8 1 1 9 9 9 5 KH domain KH_5 PF13184.6 VBB30290.1 - 0.0018 18.4 17.3 3.1 7.9 0.2 7.1 7 0 0 7 7 7 3 NusA-like KH domain DUF2431 PF10354.9 VBB30290.1 - 0.046 14.0 0.8 0.17 12.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) DUF2096 PF09869.9 VBB30290.1 - 0.076 13.1 16.3 2.6 8.1 0.4 7.9 11 1 0 11 11 11 0 Uncharacterized protein conserved in archaea (DUF2096) Alba PF01918.21 VBB30290.1 - 0.11 12.3 5.9 1.6 8.6 0.5 4.0 3 0 0 3 3 3 0 Alba DnaB_bind PF10410.9 VBB30290.1 - 0.2 11.9 0.8 0.83 9.9 0.2 2.5 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF3482 PF11981.8 VBB30290.1 - 0.23 10.8 1.8 0.24 10.8 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3482) KH_4 PF13083.6 VBB30290.1 - 0.54 10.2 16.0 15 5.5 0.0 8.4 8 1 2 10 10 10 0 KH domain DUF4974 PF16344.5 VBB30290.1 - 2.9 8.0 5.4 9.8 6.3 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4974) RhoGEF PF00621.20 VBB30291.1 - 1.3e-19 71.2 5.1 1.3e-19 71.2 5.1 3.0 2 1 0 3 3 3 1 RhoGEF domain PH_16 PF17838.1 VBB30291.1 - 6.2e-10 39.0 0.0 2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PDEase_I PF00233.19 VBB30292.1 - 8.3e-22 78.1 0.1 1.1e-21 77.6 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pet191_N PF10203.9 VBB30293.1 - 8.7e-21 74.0 6.0 1.1e-20 73.7 6.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 VBB30293.1 - 0.017 15.3 3.0 0.017 15.2 0.1 2.2 1 1 0 2 2 2 0 CHCH domain Chromo PF00385.24 VBB30294.1 - 9.1e-18 63.9 1.8 2.2e-17 62.7 0.5 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 VBB30294.1 - 0.025 14.7 0.6 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 Chromo shadow domain WHAMM-JMY_N PF15920.5 VBB30294.1 - 0.058 13.3 0.6 0.77 9.7 0.2 2.8 3 0 0 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated RWD PF05773.22 VBB30295.1 - 2.3e-15 56.9 1.1 6.3e-15 55.5 1.1 1.7 1 0 0 1 1 1 1 RWD domain SAP PF02037.27 VBB30295.1 - 2.1e-14 52.9 0.3 6.8e-14 51.2 0.2 2.0 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 VBB30295.1 - 5.8e-10 38.8 17.2 9.6e-06 25.3 0.7 3.7 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain zf-RING_2 PF13639.6 VBB30295.1 - 0.00041 20.6 10.9 0.0022 18.3 11.1 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 VBB30295.1 - 0.004 17.1 10.9 0.02 14.8 11.0 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB30295.1 - 0.0051 16.8 2.5 0.0051 16.8 2.5 2.5 2 1 1 3 3 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 VBB30295.1 - 0.028 14.2 4.5 1.5 8.7 0.1 4.2 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 VBB30295.1 - 0.079 12.8 8.6 4.2 7.3 9.7 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cytidylate_kin2 PF13189.6 VBB30295.1 - 0.13 12.4 1.0 5.3 7.1 0.2 2.6 1 1 1 2 2 2 0 Cytidylate kinase-like family CRISPR_assoc PF08798.11 VBB30295.1 - 0.2 11.7 3.3 0.44 10.6 3.3 1.5 1 0 0 1 1 1 0 CRISPR associated protein zf-C3HC4_2 PF13923.6 VBB30295.1 - 0.39 10.6 11.0 0.22 11.4 6.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 VBB30295.1 - 0.93 9.4 6.0 6.3 6.7 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 VBB30295.1 - 3.1 7.7 5.4 44 4.0 0.0 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 VBB30295.1 - 6.2 6.8 12.3 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 VBB30295.1 - 9.1 6.3 9.8 3.7 7.5 6.6 2.0 2 0 0 2 2 2 0 PHD-finger WD40 PF00400.32 VBB30296.1 - 5.4e-13 49.2 5.7 0.0011 19.8 0.2 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30296.1 - 0.00086 19.6 0.4 0.0019 18.4 0.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 VBB30296.1 - 0.011 14.5 0.0 0.098 11.4 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 VBB30296.1 - 0.015 14.0 1.3 0.042 12.5 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Y_phosphatase PF00102.27 VBB30297.1 - 3.1e-70 236.4 0.0 5.5e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB30297.1 - 0.00019 21.2 0.0 0.00063 19.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Lge1 PF11488.8 VBB30297.1 - 0.34 11.1 2.7 0.35 11.1 0.4 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Cid2 PF09774.9 VBB30298.1 - 2.4e-12 47.6 8.1 5.4e-08 33.4 0.2 2.5 2 1 1 3 3 3 2 Caffeine-induced death protein 2 DUF543 PF04418.12 VBB30298.1 - 2.2e-09 37.1 0.1 4.6e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) HTH_43 PF09904.9 VBB30298.1 - 0.23 11.4 0.8 0.73 9.8 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix WW PF00397.26 VBB30299.1 - 3.8e-09 36.5 3.1 9.7e-09 35.2 3.1 1.7 1 0 0 1 1 1 1 WW domain zinc_ribbon_9 PF14369.6 VBB30301.1 - 0.0076 16.5 0.7 0.02 15.2 0.7 1.7 1 0 0 1 1 1 1 zinc-ribbon Lactamase_B PF00753.27 VBB30302.1 - 1e-19 71.3 0.3 1.1e-18 67.9 0.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB30302.1 - 2.9e-05 23.7 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rtt106_N PF18215.1 VBB30302.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain Tmemb_cc2 PF10267.9 VBB30303.1 - 2.3e-88 297.0 9.9 3.5e-88 296.4 9.9 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein BST2 PF16716.5 VBB30303.1 - 0.022 15.4 4.3 0.022 15.4 4.3 3.3 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Dna2 PF08696.11 VBB30303.1 - 0.084 12.7 1.3 0.19 11.5 1.3 1.6 1 0 0 1 1 1 0 DNA replication factor Dna2 YvrJ PF12841.7 VBB30303.1 - 0.098 12.2 4.9 0.54 9.8 0.3 2.9 2 0 0 2 2 2 0 YvrJ protein family HAUS-augmin3 PF14932.6 VBB30303.1 - 0.28 10.7 14.3 0.012 15.2 7.3 2.1 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 KMP11 PF03037.16 VBB30303.1 - 0.31 11.8 8.5 0.38 11.6 1.0 2.7 3 0 0 3 3 2 0 Kinetoplastid membrane protein 11 GTP-bdg_M PF16360.5 VBB30303.1 - 0.37 11.4 6.3 0.64 10.7 0.1 3.6 4 0 0 4 4 4 0 GTP-binding GTPase Middle Region Lipoprotein_20 PF13942.6 VBB30303.1 - 0.99 9.3 9.1 1.9 8.4 5.0 2.5 2 0 0 2 2 2 0 YfhG lipoprotein Exonuc_VII_L PF02601.15 VBB30303.1 - 2.9 7.4 10.2 10 5.6 4.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 VBB30303.1 - 6.3 6.8 12.8 15 5.6 9.4 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 VBB30303.1 - 8.2 7.0 9.2 61 4.2 5.5 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Arrestin_N PF00339.29 VBB30304.1 - 9.5e-18 64.7 0.0 2.1e-14 53.8 0.0 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 VBB30304.1 - 1.1e-12 48.6 0.0 2.9e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 VBB30304.1 - 0.00072 18.8 0.0 0.0096 15.1 0.0 2.0 2 0 0 2 2 2 1 Rgp1 Spo0M PF07070.11 VBB30304.1 - 0.013 15.1 0.1 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 SpoOM protein Vps26 PF03643.15 VBB30304.1 - 0.12 11.4 0.0 0.83 8.6 0.0 2.3 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Ank_2 PF12796.7 VBB30305.1 - 2.3e-59 197.9 20.4 1.2e-12 48.2 0.1 8.1 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB30305.1 - 2.4e-40 136.4 25.3 3.7e-08 33.7 0.4 10.2 6 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30305.1 - 7.4e-40 130.4 21.5 1.5e-05 25.0 0.1 14.6 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 VBB30305.1 - 1.4e-39 133.7 23.1 3.7e-09 36.7 0.2 11.0 8 3 2 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 VBB30305.1 - 1.3e-34 117.1 28.3 6.8e-07 29.5 0.1 14.0 13 0 0 13 13 13 10 Ankyrin repeat DUF3915 PF13054.6 VBB30305.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) rve PF00665.26 VBB30305.1 - 0.067 13.4 0.0 1.2 9.3 0.0 2.4 1 1 1 2 2 2 0 Integrase core domain NAD_binding_1 PF00175.21 VBB30305.1 - 0.11 13.1 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain PMM PF03332.13 VBB30306.1 - 5.6e-47 160.3 0.2 5.1e-36 124.5 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 VBB30306.1 - 0.012 15.4 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-CpG_bind_C PF12269.8 VBB30307.1 - 8.9e-51 172.9 3.9 8.9e-51 172.9 3.9 4.0 3 1 0 4 4 4 2 CpG binding protein zinc finger C terminal domain PHD PF00628.29 VBB30307.1 - 8.4e-10 38.4 10.8 8.4e-10 38.4 10.8 5.0 6 1 1 7 7 7 1 PHD-finger NCU-G1 PF15065.6 VBB30307.1 - 0.34 9.9 1.8 0.62 9.0 1.8 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 PH_9 PF15410.6 VBB30308.1 - 2e-44 150.7 0.0 7.9e-44 148.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 VBB30308.1 - 2.6e-38 131.6 0.0 4.8e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 VBB30308.1 - 1.3e-08 35.3 0.0 3.9e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 PH domain NRIP1_repr_4 PF15690.5 VBB30308.1 - 0.0063 15.9 0.2 1.7 7.9 0.4 2.4 2 0 0 2 2 2 2 Nuclear receptor-interacting protein 1 repression 4 PH_13 PF16652.5 VBB30308.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 VBB30308.1 - 0.14 12.5 0.0 0.47 10.8 0.0 1.9 1 0 0 1 1 1 0 Plant pleckstrin homology-like region DIX PF00778.17 VBB30309.1 - 6.5e-21 74.0 0.1 1.2e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 DIX domain PDZ PF00595.24 VBB30309.1 - 9.3e-20 70.8 0.3 2.5e-19 69.4 0.3 1.8 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 VBB30309.1 - 1e-14 54.3 0.0 2.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled PF02377.15 VBB30309.1 - 1.2e-14 55.1 11.8 1.2e-14 55.1 11.8 1.7 2 0 0 2 2 2 1 Dishevelled specific domain PDZ_6 PF17820.1 VBB30309.1 - 9.1e-05 22.2 0.1 0.00057 19.7 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB30309.1 - 0.0019 18.5 0.1 0.0045 17.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DAZAP2 PF11029.8 VBB30309.1 - 2.9 8.8 11.3 0.35 11.8 4.9 2.7 2 1 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) wnt PF00110.19 VBB30311.1 - 2e-97 326.5 11.2 2e-97 326.5 11.2 1.6 2 0 0 2 2 2 1 wnt family Guanylate_cyc PF00211.20 VBB30311.1 - 1.4e-53 181.2 0.8 5.7e-52 176.0 0.1 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 VBB30311.1 - 1.1e-40 139.4 2.3 2.2e-40 138.5 2.3 1.5 1 0 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 VBB30311.1 - 8.3e-28 97.4 0.2 1.5e-27 96.6 0.2 1.4 1 0 0 1 1 1 1 Haem-NO-binding Ig_3 PF13927.6 VBB30312.1 - 3e-122 399.4 16.9 1.3e-13 51.3 1.0 13.5 13 0 0 13 13 13 12 Immunoglobulin domain I-set PF07679.16 VBB30312.1 - 1.3e-97 320.0 0.0 5.1e-11 42.5 0.0 13.3 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB30312.1 - 8.5e-87 285.6 1.7 2.7e-09 37.2 0.0 13.3 13 0 0 13 13 13 11 Immunoglobulin domain Laminin_B PF00052.18 VBB30312.1 - 1.3e-70 235.6 0.0 4.1e-36 123.8 0.0 2.7 2 0 0 2 2 2 2 Laminin B (Domain IV) ig PF00047.25 VBB30312.1 - 3.1e-70 232.4 0.0 1.3e-06 28.5 0.0 13.5 13 0 0 13 13 13 12 Immunoglobulin domain Laminin_EGF PF00053.24 VBB30312.1 - 1.2e-30 105.4 139.6 5.3e-08 32.9 19.6 9.4 7 2 2 9 9 9 7 Laminin EGF domain Ldl_recept_a PF00057.18 VBB30312.1 - 2.6e-26 91.5 55.3 5.1e-12 45.8 14.2 5.6 6 0 0 6 6 6 3 Low-density lipoprotein receptor domain class A V-set PF07686.17 VBB30312.1 - 1.6e-25 89.4 18.1 0.34 11.1 0.0 18.0 12 7 7 19 19 19 6 Immunoglobulin V-set domain Ig_6 PF18452.1 VBB30312.1 - 2.8e-24 84.4 0.0 0.2 11.2 0.0 10.5 12 0 0 12 12 12 6 Immunoglobulin domain Izumo-Ig PF16706.5 VBB30312.1 - 1.7e-06 28.0 3.0 1.4 9.1 0.0 8.1 10 1 1 11 11 11 1 Izumo-like Immunoglobulin domain I-set PF07679.16 VBB30313.1 - 2.1e-24 85.4 0.0 1.7e-12 47.3 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB30313.1 - 5.3e-24 84.6 0.1 1.4e-11 44.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 VBB30313.1 - 2.8e-13 49.8 0.1 8.7e-07 29.0 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 VBB30313.1 - 1.9e-12 47.3 0.0 1.9e-06 28.1 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 VBB30313.1 - 1.5e-05 24.9 0.2 0.38 10.9 0.0 3.0 1 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 VBB30313.1 - 0.0019 18.4 0.1 3.1 8.0 0.0 3.2 2 1 1 3 3 3 1 Immunoglobulin V-set domain Troponin PF00992.20 VBB30314.1 - 5.5e-05 23.5 12.4 5.5e-05 23.5 12.4 4.4 3 1 1 4 4 4 2 Troponin DUF2849 PF11011.8 VBB30314.1 - 3.3 8.4 7.9 0.17 12.5 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) RRM_occluded PF16842.5 VBB30316.1 - 0.0043 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF4523 PF15023.6 VBB30316.1 - 0.013 15.3 0.1 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 VBB30316.1 - 0.016 15.1 0.1 0.047 13.5 0.0 1.9 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mt_ATP-synt_D PF05873.12 VBB30318.1 - 8e-23 81.0 7.9 8e-23 81.0 7.9 1.4 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) FH2 PF02181.23 VBB30318.1 - 0.002 17.3 1.4 0.0029 16.8 1.4 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF4852 PF16144.5 VBB30318.1 - 0.021 15.0 2.8 0.1 12.7 2.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4852) PyocinActivator PF11112.8 VBB30318.1 - 0.028 14.5 0.3 2 8.6 0.0 3.0 3 2 0 3 3 3 0 Pyocin activator protein PrtN YolD PF08863.10 VBB30318.1 - 0.037 14.1 4.0 1.8 8.7 0.4 3.1 2 1 1 3 3 3 0 YolD-like protein NPV_P10 PF05531.12 VBB30318.1 - 0.087 13.3 1.2 5.4 7.5 0.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 VBB30318.1 - 0.16 12.1 0.8 0.59 10.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) SF3A3 PF16837.5 VBB30318.1 - 0.84 10.2 5.0 2.1 8.9 5.0 1.9 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PCI PF01399.27 VBB30319.1 - 1.3e-08 35.3 0.5 7e-08 32.9 0.0 2.2 2 1 0 2 2 2 1 PCI domain Geminin PF07412.12 VBB30319.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Geminin TPR_12 PF13424.6 VBB30319.1 - 0.32 11.3 0.9 4.1 7.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB30319.1 - 0.57 10.5 1.8 4.1 7.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF PF00209.18 VBB30320.1 - 1.7e-36 126.0 20.9 1.5e-24 86.6 6.4 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family PPR_2 PF13041.6 VBB30321.1 - 4.7e-08 33.1 1.7 0.016 15.4 0.1 3.5 1 1 2 3 3 3 2 PPR repeat family PPR_3 PF13812.6 VBB30321.1 - 4.9e-05 23.3 0.5 0.001 19.1 0.3 2.5 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 VBB30321.1 - 0.00024 20.6 0.3 0.00083 18.8 0.2 1.9 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 VBB30321.1 - 0.00083 19.4 4.6 0.19 12.0 2.1 3.9 2 1 0 2 2 2 1 PPR repeat PPR_1 PF12854.7 VBB30321.1 - 0.0013 18.4 1.3 0.28 10.9 0.1 3.4 3 0 0 3 3 3 2 PPR repeat PfUIS3 PF11567.8 VBB30321.1 - 0.053 13.9 0.4 0.14 12.5 0.4 1.7 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein ubiquitin PF00240.23 VBB30322.1 - 2.9e-32 110.3 0.9 4.6e-32 109.6 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 VBB30322.1 - 2.8e-26 91.4 4.2 6.6e-26 90.2 4.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 VBB30322.1 - 1.3e-15 56.9 0.4 2.6e-15 56.0 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 VBB30322.1 - 9.1e-05 22.8 0.5 0.00076 19.9 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 VBB30322.1 - 0.0014 18.7 0.7 0.0037 17.3 0.7 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_ribbon_SprT PF17283.2 VBB30322.1 - 0.0058 16.5 0.5 0.012 15.5 0.5 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain TBK1_ULD PF18396.1 VBB30322.1 - 0.0066 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 VBB30322.1 - 0.033 14.4 0.7 0.059 13.6 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF2407 PF10302.9 VBB30322.1 - 0.097 13.2 0.6 0.15 12.6 0.6 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.12 VBB30322.1 - 0.34 9.5 3.1 7.9 5.0 0.3 2.2 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain zf-CDGSH PF09360.10 VBB30323.1 - 1.5e-17 63.5 2.3 1.1e-09 38.3 0.3 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type IQ PF00612.27 VBB30324.1 - 1.8e-23 80.1 42.7 1.7e-06 27.3 2.3 7.5 7 0 0 7 7 7 6 IQ calmodulin-binding motif PDEase_I_N PF08499.12 VBB30324.1 - 0.15 11.9 4.1 2.4 8.1 0.0 4.1 2 1 2 4 4 4 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF420 PF04238.12 VBB30324.1 - 0.17 12.2 0.1 0.44 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF420) PDZ PF00595.24 VBB30325.1 - 1.2e-07 32.0 0.0 3.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB30325.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB30325.1 - 0.006 16.9 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 PDZ domain DUF647 PF04884.14 VBB30326.1 - 1e-89 300.3 0.9 1.4e-89 299.8 0.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Radical_SAM_C PF16199.5 VBB30327.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Radical_SAM C-terminal domain TTL PF03133.15 VBB30328.1 - 2.3e-53 181.2 3.0 3.3e-53 180.7 3.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 VBB30328.1 - 2.7e-08 33.4 0.0 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 VBB30328.1 - 8.5e-06 25.2 0.2 0.056 12.7 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 VBB30328.1 - 0.003 17.6 0.1 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 VBB30328.1 - 0.0037 16.9 0.1 0.9 9.1 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain SMC_N PF02463.19 VBB30329.1 - 3.1e-20 72.6 0.0 5.9e-20 71.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 VBB30329.1 - 1.2e-07 32.5 20.6 1.2e-07 32.5 20.6 5.1 1 1 3 4 4 2 1 AAA domain AAA_21 PF13304.6 VBB30329.1 - 0.00043 20.2 6.1 0.0086 15.9 0.1 3.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 VBB30329.1 - 0.0019 17.8 1.7 0.051 13.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain Sec20 PF03908.13 VBB30329.1 - 0.046 13.6 12.7 0.23 11.4 1.8 4.5 2 1 2 4 4 4 0 Sec20 CDC73_C PF05179.14 VBB30329.1 - 0.06 13.0 1.9 1.1 8.9 1.9 2.8 1 1 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal AAA_29 PF13555.6 VBB30329.1 - 0.064 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 VBB30329.1 - 0.088 12.7 1.4 2.5 8.0 0.1 3.2 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 VBB30329.1 - 0.27 11.7 0.1 0.27 11.7 0.1 3.9 3 2 0 3 3 2 0 ABC transporter Val_tRNA-synt_C PF10458.9 VBB30329.1 - 0.44 10.9 0.0 0.44 10.9 0.0 5.9 7 0 0 7 7 6 0 Valyl tRNA synthetase tRNA binding arm DASH_Dam1 PF08653.10 VBB30329.1 - 0.84 9.5 2.8 18 5.2 0.3 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 SNX17_FERM_C PF18116.1 VBB30330.1 - 7.9e-17 61.3 0.1 3.7e-16 59.1 0.1 2.1 1 1 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 VBB30330.1 - 8.2e-10 38.7 1.5 1.8e-09 37.5 1.5 1.5 1 0 0 1 1 1 1 PX domain Spectrin PF00435.21 VBB30331.1 - 1.1e-49 167.2 14.5 9.2e-16 58.2 0.7 4.6 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 VBB30331.1 - 5.1e-48 161.8 0.2 1.1e-22 80.2 0.0 3.3 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 VBB30331.1 - 1.6e-23 82.6 1.7 2.8e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 VBB30331.1 - 2.6e-07 30.4 0.2 1.7e-06 27.7 0.0 2.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_7 PF13499.6 VBB30331.1 - 0.045 14.2 0.0 0.21 12.1 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair DUF3398 PF11878.8 VBB30331.1 - 0.072 13.5 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Claudin_2 PF13903.6 VBB30332.1 - 0.0081 15.9 4.2 0.015 15.1 4.2 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.13 VBB30332.1 - 2.1 8.7 10.1 4.2 7.8 10.1 1.5 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) MFS_1 PF07690.16 VBB30333.1 - 8.9e-19 67.6 24.2 1.6e-17 63.5 17.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily EptA_B_N PF08019.12 VBB30333.1 - 0.0061 16.4 5.5 0.011 15.6 1.3 2.7 1 1 2 3 3 3 1 Phosphoethanolamine transferase EptA/EptB CPP1-like PF11833.8 VBB30333.1 - 0.67 9.6 4.9 0.19 11.3 1.4 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FtsX PF02687.21 VBB30333.1 - 2.3 8.7 14.5 0.65 10.5 7.1 3.0 2 1 1 3 3 3 0 FtsX-like permease family NatB_MDM20 PF09797.9 VBB30334.1 - 2.7e-79 266.9 2.1 6e-79 265.7 0.9 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1296 PF06972.11 VBB30334.1 - 0.016 15.3 0.2 0.071 13.3 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Spt4 PF06093.13 VBB30335.1 - 5.6e-31 106.5 2.0 7.1e-31 106.1 2.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger ARS2 PF04959.13 VBB30336.1 - 1.4e-48 165.9 0.0 1.4e-48 165.9 0.0 2.1 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 VBB30336.1 - 5.2e-38 129.6 3.7 1.4e-37 128.3 3.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) zf-C2H2_aberr PF17017.5 VBB30336.1 - 0.068 13.3 1.6 13 5.9 0.3 2.8 2 1 1 3 3 3 0 Aberrant zinc-finger RRM_1 PF00076.22 VBB30336.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_9 PF13901.6 VBB30337.1 - 8.7e-66 221.8 15.2 8.7e-66 221.8 15.2 2.7 3 1 0 3 3 3 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 VBB30337.1 - 1e-05 25.3 4.4 1e-05 25.3 4.4 4.1 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 VBB30337.1 - 10 6.3 25.7 3.9 7.7 4.4 3.7 3 1 1 4 4 4 0 KIAA1045 RING finger Ras PF00071.22 VBB30338.1 - 5.1e-47 159.5 0.0 8.2e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB30338.1 - 1.1e-29 103.1 0.0 2.5e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB30338.1 - 5.5e-12 45.5 0.0 8.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB30338.1 - 3.2e-09 36.5 0.0 5.6e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB30338.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 VBB30338.1 - 1.7e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 VBB30338.1 - 0.00015 21.0 1.8 0.00082 18.6 0.5 2.4 2 1 0 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 VBB30338.1 - 0.0022 17.8 1.7 0.006 16.4 0.2 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 VBB30338.1 - 0.0058 16.6 0.1 4.1 7.3 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase IRK_C PF17655.1 VBB30338.1 - 0.053 13.1 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel C-terminal domain DUF3873 PF12989.7 VBB30338.1 - 0.14 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) NACHT PF05729.12 VBB30338.1 - 0.17 11.8 0.7 0.7 9.8 0.0 2.3 3 0 0 3 3 3 0 NACHT domain Vps26 PF03643.15 VBB30340.1 - 2.2e-120 400.8 4.6 3.5e-120 400.1 4.6 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Sulfotransfer_1 PF00685.27 VBB30340.1 - 4.7e-19 68.9 0.0 1.3e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 VBB30340.1 - 2.5e-05 24.8 0.1 8.2e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family Arrestin_N PF00339.29 VBB30340.1 - 0.00037 20.6 2.4 0.0019 18.3 0.1 3.2 4 1 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Sulfotransfer_2 PF03567.14 VBB30340.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family HTH_28 PF13518.6 VBB30340.1 - 0.072 13.2 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_M61_N PF17899.1 VBB30340.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain DUF1746 PF08508.10 VBB30340.1 - 0.16 12.3 1.1 0.33 11.3 0.3 1.9 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) SNF2_N PF00176.23 VBB30341.1 - 1.4e-49 168.7 0.0 2.4e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB30341.1 - 2.8e-15 56.6 0.0 7.2e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB30341.1 - 5.9e-12 45.9 0.0 1.5e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB30341.1 - 4.8e-07 29.7 0.0 8.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 VBB30341.1 - 2.5e-05 23.6 0.1 0.00012 21.3 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 VBB30341.1 - 0.0038 17.5 0.0 0.0089 16.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) ERCC3_RAD25_C PF16203.5 VBB30341.1 - 0.0057 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 VBB30341.1 - 0.043 13.1 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 VBB30341.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 VBB30342.1 - 5.9e-53 176.5 45.2 2.3e-09 36.9 0.1 9.7 3 2 6 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 VBB30342.1 - 1.7e-39 133.2 56.1 3.5e-08 33.6 1.9 10.6 7 3 5 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB30342.1 - 1.5e-11 43.2 46.8 1.7 9.5 0.0 16.5 17 1 0 17 17 17 5 Leucine Rich Repeat LRR_9 PF14580.6 VBB30342.1 - 1.4e-07 31.1 27.3 0.023 14.2 0.3 5.6 2 2 3 5 5 5 5 Leucine-rich repeat LRR_5 PF13306.6 VBB30342.1 - 0.00016 21.6 0.9 0.13 12.2 0.2 4.2 2 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 VBB30342.1 - 7.3 6.9 50.8 0.3 11.2 0.5 12.4 15 0 0 15 15 15 0 Leucine Rich repeat ABC_tran PF00005.27 VBB30343.1 - 1.7e-54 184.0 0.0 1.4e-27 96.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 VBB30343.1 - 1.4e-23 83.6 60.1 6.6e-15 55.1 17.7 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 VBB30343.1 - 6.5e-22 78.7 3.4 2.5e-07 30.8 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 VBB30343.1 - 3.6e-07 29.9 1.1 0.045 13.2 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 VBB30343.1 - 1.2e-05 26.0 0.5 0.16 12.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 VBB30343.1 - 9.2e-05 22.1 1.0 0.05 13.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 VBB30343.1 - 0.0002 21.5 0.0 0.78 10.0 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.24 VBB30343.1 - 0.0044 16.5 52.7 0.047 13.1 12.6 5.5 4 1 0 4 4 4 2 ABC-2 type transporter RsgA_GTPase PF03193.16 VBB30343.1 - 0.02 14.8 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 VBB30343.1 - 0.035 13.8 0.1 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 VBB30343.1 - 0.089 13.2 0.1 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 VBB30343.1 - 0.11 12.0 0.3 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 VBB30343.1 - 0.25 10.9 0.9 12 5.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain WD40 PF00400.32 VBB30344.1 - 4.3e-07 30.5 0.1 56 4.8 0.0 6.1 5 1 1 6 6 6 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30344.1 - 3.6e-06 27.2 0.0 2.4 8.5 0.0 4.7 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain FAM193_C PF15914.5 VBB30344.1 - 0.053 13.3 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 FAM193 family C-terminal Formyl_trans_C PF02911.18 VBB30344.1 - 0.14 12.4 0.0 0.6 10.4 0.0 2.0 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain Pkinase_Tyr PF07714.17 VBB30345.1 - 2.5e-64 217.1 0.3 3.3e-63 213.4 0.1 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30345.1 - 1.9e-34 119.2 0.0 4.7e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain MBT PF02820.18 VBB30346.1 - 3.1e-64 213.3 0.0 2.8e-18 66.0 0.0 4.2 4 0 0 4 4 4 4 mbt repeat ABC1 PF03109.16 VBB30347.1 - 4.7e-27 94.5 0.1 4.6e-25 88.1 0.1 2.4 1 1 0 1 1 1 1 ABC1 family Pkinase PF00069.25 VBB30347.1 - 7.4e-06 25.5 0.4 9e-05 22.0 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 VBB30347.1 - 0.0058 16.6 0.1 0.24 11.3 0.3 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 VBB30347.1 - 0.012 14.9 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase DUF3370 PF11850.8 VBB30347.1 - 0.055 12.4 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) Cytochrome_P460 PF16694.5 VBB30348.1 - 0.038 14.3 0.8 0.068 13.5 0.6 1.5 1 1 0 1 1 1 0 Cytochrome P460 Ribosomal_S30 PF04758.14 VBB30348.1 - 0.041 14.1 0.3 0.078 13.2 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S30 Macoilin PF09726.9 VBB30348.1 - 3.4 6.1 5.5 4 5.9 5.5 1.0 1 0 0 1 1 1 0 Macoilin family 2-Hacid_dh_C PF02826.19 VBB30349.1 - 3.6e-47 160.0 0.0 6.3e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 VBB30349.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase BAR PF03114.18 VBB30350.1 - 2.6e-12 46.9 6.2 2.6e-12 46.9 6.2 1.6 2 0 0 2 2 2 1 BAR domain DUF5339 PF17274.2 VBB30350.1 - 0.065 14.1 2.4 0.065 14.1 2.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5339) KIP1 PF07765.12 VBB30350.1 - 0.3 11.2 2.5 0.86 9.8 1.1 2.4 1 1 0 2 2 2 0 KIP1-like protein Flagellin_C PF00700.21 VBB30350.1 - 0.59 10.5 4.6 0.65 10.4 0.8 2.7 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region CENP-H PF05837.12 VBB30350.1 - 1.4 9.3 0.0 1.4 9.3 0.0 3.3 4 0 0 4 4 4 0 Centromere protein H (CENP-H) Integrase_H2C2 PF17921.1 VBB30351.1 - 9.6e-07 28.8 5.4 1.6e-06 28.1 5.4 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 VBB30351.1 - 0.038 14.2 0.0 0.077 13.2 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 VBB30351.1 - 0.045 13.5 0.1 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain RP853 PF17542.2 VBB30351.1 - 0.21 10.7 0.7 0.44 9.6 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized RP853 Proteasome PF00227.26 VBB30352.1 - 3.3e-42 144.1 1.1 4.7e-42 143.6 1.1 1.2 1 0 0 1 1 1 1 Proteasome subunit TB2_DP1_HVA22 PF03134.19 VBB30353.1 - 8.3e-16 57.7 1.0 1.2e-15 57.1 1.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Met_10 PF02475.16 VBB30354.1 - 2.5e-28 99.2 0.0 6.9e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 VBB30354.1 - 0.0012 18.5 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 VBB30354.1 - 0.0018 17.8 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 VBB30354.1 - 0.002 18.0 0.1 0.0065 16.3 0.0 1.8 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase TRM PF02005.16 VBB30354.1 - 0.0049 16.1 0.3 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 VBB30354.1 - 0.0079 16.9 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 VBB30354.1 - 0.015 14.9 0.4 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 VBB30354.1 - 0.041 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 VBB30355.1 - 0.00017 22.3 0.1 0.00066 20.4 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat EF-hand_7 PF13499.6 VBB30356.1 - 1.3e-17 64.0 6.7 8.9e-10 38.9 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 VBB30356.1 - 1.5e-17 61.9 4.6 4.7e-06 26.1 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 VBB30356.1 - 2.6e-17 61.0 12.3 3e-07 29.5 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 VBB30356.1 - 1.3e-10 40.9 8.9 1.9e-07 30.8 0.8 3.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB30356.1 - 7.5e-10 37.9 9.8 7.9e-05 22.0 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 VBB30356.1 - 8.4e-07 28.9 0.2 0.048 13.6 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 VBB30356.1 - 0.00065 20.0 0.0 0.021 15.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 VBB30356.1 - 0.028 14.7 2.5 1.1 9.6 0.0 3.2 1 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 VBB30356.1 - 0.04 14.1 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain Homez PF11569.8 VBB30356.1 - 0.045 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF4367 PF14285.6 VBB30356.1 - 0.065 13.7 1.0 0.14 12.6 0.1 2.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4367) ParA PF10609.9 VBB30358.1 - 1.2e-91 306.5 0.0 3.2e-91 305.2 0.0 1.8 2 0 0 2 2 1 1 NUBPL iron-transfer P-loop NTPase AAA PF00004.29 VBB30358.1 - 5.1e-41 140.2 0.0 4.5e-38 130.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad10 PF03834.14 VBB30358.1 - 4.4e-33 113.7 0.0 1.1e-32 112.5 0.0 1.7 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) CbiA PF01656.23 VBB30358.1 - 6.3e-11 42.4 0.1 8e-10 38.9 0.0 3.0 3 2 0 3 3 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_lid_3 PF17862.1 VBB30358.1 - 1.3e-09 37.6 1.4 3.1e-09 36.5 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 VBB30358.1 - 3.6e-08 33.3 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 VBB30358.1 - 4.3e-08 33.7 0.5 0.018 15.4 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_31 PF13614.6 VBB30358.1 - 1e-07 32.0 0.2 8e-07 29.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 VBB30358.1 - 2.8e-07 30.6 0.2 0.0054 16.7 0.1 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 VBB30358.1 - 8.2e-07 29.3 0.0 0.00074 19.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 VBB30358.1 - 1.6e-06 28.4 3.1 0.033 14.5 0.3 4.0 4 1 0 4 4 2 2 AAA domain IstB_IS21 PF01695.17 VBB30358.1 - 4.5e-06 26.5 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 VBB30358.1 - 5.9e-06 26.1 0.0 0.00065 19.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 VBB30358.1 - 9.6e-06 26.2 0.3 0.25 11.9 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_2 PF07724.14 VBB30358.1 - 1.1e-05 25.7 0.0 0.00023 21.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 VBB30358.1 - 1.4e-05 25.1 1.3 0.17 11.8 0.1 2.8 2 1 0 3 3 2 2 NACHT domain AAA_14 PF13173.6 VBB30358.1 - 1.7e-05 24.9 0.5 0.022 14.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain TIP49 PF06068.13 VBB30358.1 - 2e-05 24.0 0.4 0.025 13.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 VBB30358.1 - 2.1e-05 24.2 0.1 0.018 14.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 VBB30358.1 - 3.6e-05 24.1 0.1 0.46 10.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 VBB30358.1 - 8.8e-05 22.0 0.6 0.015 14.6 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 VBB30358.1 - 9.4e-05 22.4 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArsA_ATPase PF02374.15 VBB30358.1 - 9.7e-05 21.7 3.1 0.00012 21.4 0.1 2.7 2 1 2 4 4 3 1 Anion-transporting ATPase AAA_7 PF12775.7 VBB30358.1 - 0.00018 21.1 0.1 0.32 10.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 VBB30358.1 - 0.00031 20.0 0.1 0.33 10.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_26 PF13500.6 VBB30358.1 - 0.00038 20.3 0.0 0.008 16.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 VBB30358.1 - 0.00041 19.9 0.2 0.36 10.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein MipZ PF09140.11 VBB30358.1 - 0.00051 19.4 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 VBB30358.1 - 0.00097 18.7 0.0 0.038 13.4 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 VBB30358.1 - 0.001 18.4 0.1 1 8.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 VBB30358.1 - 0.0012 18.6 0.4 1.1 9.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 VBB30358.1 - 0.0013 18.5 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 VBB30358.1 - 0.0044 16.8 0.0 4.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 VBB30358.1 - 0.0054 16.7 0.1 0.35 10.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 VBB30358.1 - 0.0061 17.1 0.0 1.7 9.2 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 VBB30358.1 - 0.0083 16.1 0.2 0.17 11.8 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain DnaB_C PF03796.15 VBB30358.1 - 0.013 14.8 0.1 0.31 10.4 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ResIII PF04851.15 VBB30358.1 - 0.016 15.2 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit APS_kinase PF01583.20 VBB30358.1 - 0.018 15.0 0.2 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase Guanylate_kin PF00625.21 VBB30358.1 - 0.02 14.6 0.1 0.6 9.8 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.6 VBB30358.1 - 0.021 15.1 0.2 0.17 12.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain HHH_5 PF14520.6 VBB30358.1 - 0.028 15.0 0.1 0.088 13.4 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain CBP_BcsQ PF06564.12 VBB30358.1 - 0.03 13.8 0.1 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ ATPase PF06745.13 VBB30358.1 - 0.036 13.4 0.0 5.8 6.2 0.0 2.8 2 1 1 3 3 3 0 KaiC DUF2075 PF09848.9 VBB30358.1 - 0.039 13.2 0.1 8 5.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 VBB30358.1 - 0.062 12.9 0.6 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 VBB30358.1 - 0.072 12.7 0.2 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 VBB30358.1 - 0.11 12.4 0.3 13 5.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 VBB30358.1 - 0.15 12.4 0.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain UBZ_FAAP20 PF15750.5 VBB30358.1 - 4.1 7.4 7.9 0.086 12.8 0.3 2.2 2 0 0 2 2 1 0 Ubiquitin-binding zinc-finger ketoacyl-synt PF00109.26 VBB30359.1 - 2.4e-45 155.1 1.6 3.8e-45 154.4 0.3 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 VBB30359.1 - 4.6e-21 75.0 0.5 7.9e-20 71.0 0.5 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 VBB30359.1 - 0.00067 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 VBB30359.1 - 0.057 13.3 0.2 0.75 9.7 0.2 2.5 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C2 PF00168.30 VBB30360.1 - 2.2e-13 50.4 0.2 2.6e-13 50.1 0.2 1.1 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 VBB30360.1 - 0.00011 21.7 0.1 0.00017 21.2 0.1 1.4 1 1 0 1 1 1 1 CEP76 C2 domain HELP PF03451.14 VBB30361.1 - 6.7e-20 70.7 0.0 1.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 VBB30361.1 - 1.6e-16 60.4 8.7 0.36 11.8 0.0 11.1 12 0 0 12 12 12 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30361.1 - 2.3e-12 47.0 0.5 0.011 16.0 0.0 6.3 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB30361.1 - 0.0073 15.7 0.5 0.2 10.9 0.0 3.1 3 1 1 4 4 4 1 WD40-like domain UBX PF00789.20 VBB30363.1 - 0.0024 18.0 2.3 0.015 15.5 0.1 3.0 3 0 0 3 3 3 1 UBX domain DUF4101 PF13355.6 VBB30363.1 - 0.022 15.2 0.4 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) DUF4743 PF15916.5 VBB30363.1 - 0.34 10.9 2.9 0.98 9.4 2.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) MIT_C PF16565.5 VBB30364.1 - 3.3e-31 108.1 0.1 6.6e-31 107.2 0.1 1.5 1 1 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 VBB30364.1 - 3.5e-16 59.0 1.0 5.2e-16 58.5 0.6 1.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF982 PF06169.12 VBB30364.1 - 0.11 12.6 0.0 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF982) MADF_DNA_bdg PF10545.9 VBB30366.1 - 0.017 15.4 1.4 0.02 15.2 1.4 1.1 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UQ_con PF00179.26 VBB30367.1 - 1.2e-27 96.3 0.0 1.4e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Astacin PF01400.24 VBB30368.1 - 2.7e-62 209.8 0.1 4.4e-62 209.1 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TTR-52 PF01060.23 VBB30368.1 - 1.1e-12 48.5 0.0 3.2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Transthyretin-like family Metallophos_2 PF12850.7 VBB30369.1 - 3.5e-23 82.6 0.2 4e-23 82.4 0.2 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 VBB30369.1 - 7.9e-05 23.2 0.6 0.028 14.9 0.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Nsp2a_N PF17896.1 VBB30369.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Histone PF00125.24 VBB30372.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 VBB30372.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 VBB30372.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 VBB30372.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 VBB30372.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UCH PF00443.29 VBB30373.1 - 1.1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_photolyase PF00875.18 VBB30373.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.4 1 1 0 1 1 1 0 DNA photolyase EF-hand_4 PF12763.7 VBB30374.1 - 8.5e-37 125.3 0.0 2e-18 66.2 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 VBB30374.1 - 2.3e-11 42.4 0.1 0.055 13.0 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 VBB30374.1 - 1.5e-08 35.0 0.4 0.00015 22.2 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB30374.1 - 1.7e-06 27.5 0.1 0.23 11.5 0.1 4.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 VBB30374.1 - 1.5e-05 24.2 1.9 0.14 11.7 0.2 2.9 2 0 0 2 2 2 2 EF hand DUF3450 PF11932.8 VBB30374.1 - 0.003 16.9 28.1 0.19 11.0 10.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Atg14 PF10186.9 VBB30374.1 - 0.0064 15.6 14.6 0.0064 15.6 14.6 2.2 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 VBB30374.1 - 0.0079 16.3 33.6 0.0079 16.3 33.6 2.3 1 1 1 2 2 2 1 Tropomyosin like ERM PF00769.19 VBB30374.1 - 0.067 13.0 39.4 0.93 9.3 16.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 VBB30374.1 - 0.072 13.3 38.0 0.21 11.8 5.6 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 VBB30374.1 - 0.12 9.8 28.8 0.18 9.3 28.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.16 VBB30374.1 - 0.14 12.4 25.7 0.044 14.0 16.0 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein ATG16 PF08614.11 VBB30374.1 - 0.23 11.7 39.3 0.39 10.9 17.9 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 VBB30374.1 - 0.24 10.9 32.9 0.84 9.1 33.0 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain ADIP PF11559.8 VBB30374.1 - 0.27 11.3 34.3 0.079 13.0 14.0 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 VBB30374.1 - 0.28 11.0 33.4 0.021 14.7 11.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EF-hand_8 PF13833.6 VBB30374.1 - 0.32 10.9 4.0 25 4.8 0.0 4.0 4 1 1 5 5 5 0 EF-hand domain pair TMF_DNA_bd PF12329.8 VBB30374.1 - 0.32 11.0 44.4 0.45 10.5 10.7 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.20 VBB30374.1 - 0.6 9.4 39.2 1.2 8.5 14.9 2.5 1 1 1 2 2 2 0 Tropomyosin BRE1 PF08647.11 VBB30374.1 - 0.68 10.0 37.3 2.4 8.3 14.4 2.7 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase THOC7 PF05615.13 VBB30374.1 - 0.98 9.7 33.5 2.8 8.2 17.5 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 T3SSipB PF16535.5 VBB30374.1 - 3.2 8.2 14.9 1.8 9.0 8.4 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB Seryl_tRNA_N PF02403.22 VBB30374.1 - 3.5 7.9 32.3 3.3 8.0 10.8 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Vac_Fusion PF02346.16 VBB30374.1 - 3.7 7.3 8.0 8.1 6.2 1.2 3.0 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 NPV_P10 PF05531.12 VBB30374.1 - 5 7.7 13.8 4.6 7.8 3.4 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 VBB30374.1 - 6.6 6.3 42.1 10 5.7 25.6 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RasGAP_C PF03836.15 VBB30374.1 - 6.6 6.9 25.0 1.3 9.1 10.1 3.0 1 1 2 3 3 3 0 RasGAP C-terminus zf-C4H2 PF10146.9 VBB30374.1 - 7.4 6.8 28.5 0.03 14.6 9.0 2.7 2 1 1 3 3 2 0 Zinc finger-containing protein Spc7 PF08317.11 VBB30374.1 - 8.6 5.1 39.4 0.51 9.2 17.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Piwi PF02171.17 VBB30375.1 - 1.2e-85 287.4 0.0 1.8e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 VBB30375.1 - 2.7e-08 33.7 0.3 3e-07 30.3 0.1 2.3 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 VBB30375.1 - 8.6e-07 29.2 0.0 2.8e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 VBB30375.1 - 3.3e-06 27.7 0.0 9.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 VBB30375.1 - 0.001 18.7 0.1 0.0028 17.3 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain Tudor-knot PF11717.8 VBB30375.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Beta-lactamase PF00144.24 VBB30376.1 - 1.6e-48 165.7 0.0 1.9e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF4861 PF16153.5 VBB30376.1 - 0.032 13.2 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) Pes-10 PF07149.11 VBB30377.1 - 0.016 14.2 0.7 0.034 13.2 0.7 1.4 1 0 0 1 1 1 0 Pes-10 CobT PF06213.12 VBB30377.1 - 0.019 14.3 0.5 0.04 13.3 0.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MA3 PF02847.17 VBB30378.1 - 3.5e-17 62.4 4.4 1e-16 60.9 1.3 2.7 2 0 0 2 2 2 1 MA3 domain ParB PF08775.10 VBB30378.1 - 0.35 11.4 5.8 1.1 9.7 5.8 1.9 1 0 0 1 1 1 0 ParB family Pkinase PF00069.25 VBB30379.1 - 5.7e-65 219.3 0.0 8e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 VBB30379.1 - 4.7e-32 110.4 16.9 4.1e-11 43.3 0.1 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 VBB30379.1 - 2e-28 99.4 0.0 3.1e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 VBB30379.1 - 1.8e-21 76.2 4.8 0.00035 21.1 0.3 5.2 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB30379.1 - 2.2e-20 72.4 5.1 1.2e-07 31.8 0.1 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30379.1 - 1.8e-18 64.7 8.0 0.0017 18.7 0.0 7.4 7 1 0 7 7 6 3 Ankyrin repeat Ank PF00023.30 VBB30379.1 - 3.5e-17 62.0 5.6 4.4e-05 23.7 0.1 6.1 5 0 0 5 5 5 3 Ankyrin repeat Kdo PF06293.14 VBB30379.1 - 4.3e-07 29.5 0.0 7.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB30379.1 - 8.3e-05 21.5 0.0 0.00018 20.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 VBB30379.1 - 0.00022 20.6 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 VBB30379.1 - 0.0084 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 VBB30379.1 - 0.09 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.30 VBB30381.1 - 7.7e-21 74.3 0.1 2.3e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain HydF_tetramer PF18133.1 VBB30381.1 - 0.065 13.0 0.2 0.065 13.0 0.2 2.3 3 0 0 3 3 3 0 Hydrogen maturase F tetramerization domain Tetrabrachion PF11401.8 VBB30381.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetrabrachion Macoilin PF09726.9 VBB30381.1 - 0.18 10.4 11.0 0.45 9.0 9.6 1.8 1 1 1 2 2 2 0 Macoilin family Androgen_recep PF02166.16 VBB30381.1 - 0.39 9.5 4.7 0.63 8.8 4.7 1.2 1 0 0 1 1 1 0 Androgen receptor FHA PF00498.26 VBB30382.1 - 2.7e-19 69.3 0.5 5.2e-19 68.4 0.1 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 VBB30382.1 - 3.5e-08 33.6 0.0 8.3e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Vpu PF00558.19 VBB30382.1 - 0.093 12.5 3.2 0.16 11.7 3.2 1.3 1 0 0 1 1 1 0 Vpu protein DUF842 PF05811.13 VBB30383.1 - 2.9e-41 140.2 5.7 3.3e-41 140.1 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Ank_4 PF13637.6 VBB30383.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) zf-Tim10_DDP PF02953.15 VBB30383.1 - 0.41 10.3 9.4 0.068 12.8 0.9 2.9 1 1 2 3 3 3 0 Tim10/DDP family zinc finger DEAD PF00270.29 VBB30384.1 - 1.3e-42 145.5 0.1 2e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB30384.1 - 2.2e-29 102.0 1.4 2.7e-28 98.5 0.7 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain BCDHK_Adom3 PF10436.9 VBB30385.1 - 7.3e-33 113.7 0.3 9.8e-33 113.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 VBB30385.1 - 7.6e-12 45.7 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fib_alpha PF08702.10 VBB30385.1 - 0.0025 18.0 0.8 0.0037 17.5 0.8 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family HATPase_c_3 PF13589.6 VBB30385.1 - 0.0037 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF148 PF02520.17 VBB30385.1 - 0.15 12.2 0.8 0.33 11.1 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 TMPIT PF07851.13 VBB30386.1 - 7.4e-124 413.2 10.9 8.6e-124 413.0 10.9 1.0 1 0 0 1 1 1 1 TMPIT-like protein MADF_DNA_bdg PF10545.9 VBB30388.1 - 5.3e-18 65.1 0.1 1.1e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB30388.1 - 2.4e-05 24.6 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 VBB30388.1 - 0.0013 18.8 0.5 0.0024 17.9 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Reprolysin PF01421.19 VBB30389.1 - 1.1e-12 48.3 0.3 2.9e-12 46.9 0.3 1.7 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease HLH PF00010.26 VBB30389.1 - 5e-11 42.4 1.4 1.3e-10 41.0 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Reprolysin_5 PF13688.6 VBB30389.1 - 6.8e-06 26.4 0.9 6.4e-05 23.2 0.0 2.7 1 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 VBB30389.1 - 2e-05 25.1 0.1 7.6e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like MOZ_SAS PF01853.18 VBB30390.1 - 0.00021 21.0 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family DUF1421 PF07223.11 VBB30390.1 - 0.026 14.4 0.1 0.049 13.5 0.1 1.6 1 1 0 1 1 1 0 UBA-like domain (DUF1421) Inhibitor_I29 PF08246.12 VBB30391.1 - 2.3e-07 31.1 0.2 2.8e-07 30.9 0.2 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Actin_micro PF17003.5 VBB30392.1 - 0.0066 15.7 0.6 0.0066 15.7 0.6 4.2 4 1 0 4 4 4 2 Putative actin-like family CRAL_TRIO PF00650.20 VBB30396.1 - 3.8e-21 75.5 0.1 4.6e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain COX6C PF02937.15 VBB30398.1 - 0.00023 21.2 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc BEN PF10523.9 VBB30399.1 - 0.0016 18.6 0.4 0.34 11.2 0.1 2.8 2 0 0 2 2 2 2 BEN domain MADF_DNA_bdg PF10545.9 VBB30399.1 - 0.0056 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-BED PF02892.15 VBB30401.1 - 1.6e-07 31.2 0.1 3.3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger DUF19 PF01579.18 VBB30402.1 - 1.2e-05 25.1 3.4 1.6e-05 24.8 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF19) CPG4 PF15481.6 VBB30402.1 - 1.7e-05 25.3 2.4 1.7e-05 25.3 2.4 1.9 1 1 1 2 2 2 1 Chondroitin proteoglycan 4 LOH1CR12 PF10158.9 VBB30402.1 - 0.1 12.6 0.1 0.59 10.2 0.0 2.2 1 1 1 2 2 2 0 Tumour suppressor protein Acetyltransf_18 PF18014.1 VBB30404.1 - 5e-08 32.8 0.0 4.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain AurF PF11583.8 VBB30404.1 - 0.12 11.6 0.3 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 P-aminobenzoate N-oxygenase AurF Glyco_trans_1_4 PF13692.6 VBB30406.1 - 1.6e-09 38.3 0.0 2e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 VBB30406.1 - 5.4e-07 29.3 0.0 2.2e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 VBB30406.1 - 0.0003 21.3 0.0 0.0033 17.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 VBB30406.1 - 0.0015 18.6 0.5 1.8 8.5 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 VBB30406.1 - 0.006 17.0 0.1 0.019 15.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 GTP_EFTU PF00009.27 VBB30407.1 - 9.5e-31 106.9 0.1 9.5e-31 106.9 0.1 4.4 4 1 0 4 4 4 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 VBB30407.1 - 4.9e-19 68.4 0.0 1.4e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 VBB30407.1 - 4.6e-16 58.5 0.0 1.6e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 VBB30407.1 - 2.1e-12 47.3 9.4 1.2e-08 35.2 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 VBB30407.1 - 8.5e-07 29.1 0.0 7.2e-06 26.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 VBB30407.1 - 0.0078 16.4 0.0 0.031 14.5 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 VBB30407.1 - 0.05 13.4 0.0 0.05 13.4 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 VBB30407.1 - 0.078 13.0 0.2 0.078 13.0 0.2 4.5 2 1 0 2 2 2 0 Dynamin family Collagen PF01391.18 VBB30410.1 - 1.9e-23 81.9 82.1 4.6e-10 39.1 31.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB30410.1 - 1.1e-07 31.8 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Neur_chan_LBD PF02931.23 VBB30411.1 - 1.3e-53 181.7 2.2 1.6e-53 181.3 2.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB30411.1 - 4.1e-20 72.9 17.5 5.5e-20 72.5 17.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Fzo_mitofusin PF04799.13 VBB30413.1 - 3.8e-50 169.6 0.3 2.9e-49 166.7 0.1 2.5 2 0 0 2 2 2 1 fzo-like conserved region Dynamin_N PF00350.23 VBB30413.1 - 3.7e-25 88.9 0.0 1.6e-24 86.9 0.0 2.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 VBB30413.1 - 6.9e-07 29.3 0.0 2.7e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 VBB30413.1 - 0.0077 15.6 0.3 0.14 11.5 0.0 2.7 3 0 0 3 3 3 1 AIG1 family DUF948 PF06103.11 VBB30413.1 - 0.044 14.0 0.7 0.19 12.0 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RsgA_GTPase PF03193.16 VBB30413.1 - 0.1 12.5 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase NiFe_hyd_3_EhaA PF17367.2 VBB30414.1 - 1.6 8.9 13.3 0.23 11.6 3.3 2.9 2 1 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A Arrestin_C PF02752.22 VBB30415.1 - 2e-10 41.2 2.9 6.2e-10 39.6 1.7 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 VBB30415.1 - 0.029 14.4 0.1 0.1 12.6 0.0 2.0 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain UQ_con PF00179.26 VBB30417.1 - 2.9e-46 156.6 0.0 3.7e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PKI PF02827.16 VBB30417.1 - 1.1e-08 35.2 0.4 2.6e-08 33.9 0.2 1.8 2 0 0 2 2 2 1 cAMP-dependent protein kinase inhibitor UEV PF05743.13 VBB30417.1 - 0.019 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 VBB30417.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 VBB30417.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Ras PF00071.22 VBB30418.1 - 2.9e-22 79.0 0.0 3.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB30418.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 VBB30418.1 - 0.079 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B GM_CSF PF01109.17 VBB30419.1 - 0.079 13.1 1.8 0.82 9.8 0.2 2.6 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Ras PF00071.22 VBB30420.1 - 3.7e-32 111.1 0.2 4.1e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB30420.1 - 9.5e-29 100.1 0.1 1.1e-28 99.8 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB30420.1 - 5e-10 39.1 0.1 5.4e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 VBB30420.1 - 1.7e-05 24.3 0.0 2.1e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 VBB30420.1 - 0.00037 20.5 0.0 0.00047 20.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 VBB30420.1 - 0.0004 19.8 0.0 0.00045 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 VBB30420.1 - 0.029 13.9 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 VBB30420.1 - 0.038 13.5 0.0 0.3 10.6 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Cyt-b5 PF00173.28 VBB30421.1 - 7.4e-19 67.7 0.0 1.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Orf78 PF06024.12 VBB30421.1 - 0.0041 17.4 0.1 0.0059 16.9 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) Guanylate_cyc PF00211.20 VBB30422.1 - 1.5e-64 217.0 0.1 2.3e-64 216.4 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 VBB30422.1 - 6.2e-47 160.4 0.9 9.7e-47 159.8 0.9 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 VBB30422.1 - 6e-34 117.5 0.0 1.3e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30422.1 - 6.7e-25 87.9 0.2 2e-24 86.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 VBB30422.1 - 0.00023 20.7 1.4 0.00051 19.5 1.4 1.6 1 0 0 1 1 1 1 Heme NO binding associated CTK3 PF12243.8 VBB30423.1 - 0.1 12.6 0.1 3 7.9 0.0 2.3 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Ion_trans_2 PF07885.16 VBB30424.1 - 6.3e-09 35.7 4.5 6.3e-09 35.7 4.5 2.5 2 1 0 2 2 2 1 Ion channel Ninjurin PF04923.12 VBB30424.1 - 0.13 12.2 1.0 0.54 10.2 1.0 2.0 1 1 0 1 1 1 0 Ninjurin Nup192 PF11894.8 VBB30425.1 - 1e-79 268.3 38.2 2.1e-69 234.1 19.0 3.2 2 2 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 GATA PF00320.27 VBB30426.1 - 2.8e-09 36.4 3.3 6.4e-09 35.3 3.3 1.7 1 0 0 1 1 1 1 GATA zinc finger TGF_beta PF00019.20 VBB30427.1 - 7.1e-31 107.3 0.1 1.1e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 VBB30427.1 - 4.4e-14 52.8 0.0 8.7e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 TGF-beta propeptide EHN PF06441.12 VBB30427.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus TPR_1 PF00515.28 VBB30428.1 - 1.3e-47 157.7 22.9 3.1e-09 36.2 0.2 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 VBB30428.1 - 1.5e-38 127.8 19.0 1.7e-08 33.9 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 VBB30428.1 - 1.8e-24 85.8 9.6 3e-11 43.4 0.2 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30428.1 - 5.4e-23 80.4 20.9 1.8e-10 40.3 0.0 5.9 3 2 3 6 6 6 3 TPR repeat TPR_8 PF13181.6 VBB30428.1 - 5.4e-22 76.1 20.8 0.00047 20.2 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30428.1 - 6.9e-21 73.2 5.6 0.0016 19.1 0.0 7.1 2 2 6 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 VBB30428.1 - 7e-19 68.1 11.3 7.4e-05 23.2 0.0 4.6 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30428.1 - 2.3e-18 66.5 3.2 2.2e-05 25.0 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB30428.1 - 1.3e-15 56.7 9.7 0.0026 17.6 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat STI1 PF17830.1 VBB30428.1 - 3.6e-15 55.6 0.9 2.2e-14 53.1 0.3 2.6 3 0 0 3 3 2 1 STI1 domain TPR_17 PF13431.6 VBB30428.1 - 4.8e-15 54.8 15.5 0.00023 21.3 0.1 6.4 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB30428.1 - 1.3e-14 53.0 7.0 0.0048 16.8 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB30428.1 - 9.7e-11 41.8 11.3 1.7e-05 24.9 3.1 3.4 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 VBB30428.1 - 5.2e-07 29.6 10.9 0.14 12.3 0.0 5.7 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 VBB30428.1 - 6.6e-07 29.6 12.7 1.8 9.4 0.0 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB30428.1 - 1.3e-06 28.5 2.1 0.0052 16.9 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB30428.1 - 1.2e-05 24.7 2.2 0.023 13.9 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 VBB30428.1 - 3.4e-05 23.0 9.3 0.0021 17.1 0.5 3.1 1 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 VBB30428.1 - 4.7e-05 23.2 12.4 0.44 10.2 0.0 4.2 1 1 2 4 4 4 2 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 VBB30428.1 - 0.0013 18.1 1.7 0.35 10.4 0.0 4.0 5 0 0 5 5 4 1 SHNi-TPR MIT PF04212.18 VBB30428.1 - 0.014 15.5 19.0 4.1 7.6 0.2 5.9 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain RNase_T PF00929.24 VBB30428.1 - 0.017 15.7 1.0 0.16 12.5 0.1 2.3 1 1 0 2 2 2 0 Exonuclease BTAD PF03704.17 VBB30428.1 - 0.018 15.5 4.8 0.55 10.6 0.3 3.0 2 1 1 3 3 3 0 Bacterial transcriptional activator domain RE_TdeIII PF09520.10 VBB30428.1 - 0.018 14.7 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII PPR PF01535.20 VBB30428.1 - 0.02 15.1 5.1 8.3 6.9 0.0 5.2 6 0 0 6 6 5 0 PPR repeat LemA PF04011.12 VBB30428.1 - 0.057 13.3 0.2 7.7 6.4 0.1 2.7 2 0 0 2 2 2 0 LemA family SRP_TPR_like PF17004.5 VBB30428.1 - 0.11 12.5 11.9 0.49 10.4 3.1 3.6 1 1 2 3 3 3 0 Putative TPR-like repeat FAT PF02259.23 VBB30428.1 - 0.12 11.6 2.0 1.5 8.0 1.9 2.4 1 1 0 1 1 1 0 FAT domain HiaBD2 PF15403.6 VBB30428.1 - 0.14 12.5 1.2 0.29 11.5 1.2 1.5 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Coatomer_E PF04733.14 VBB30428.1 - 0.16 11.4 6.2 3.5 7.0 0.5 3.2 2 1 1 3 3 3 0 Coatomer epsilon subunit SPO22 PF08631.10 VBB30428.1 - 0.22 11.0 2.8 3.3 7.1 0.1 3.3 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like SPOUT_MTase PF02590.17 VBB30428.1 - 0.43 10.6 2.1 1 9.3 0.1 2.3 1 1 2 3 3 3 0 Predicted SPOUT methyltransferase Alkyl_sulf_dimr PF14863.6 VBB30428.1 - 0.81 10.1 4.5 27 5.2 0.0 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation RPN7 PF10602.9 VBB30428.1 - 5.7 6.6 8.7 3.5 7.3 2.5 3.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF4030 PF13222.6 VBB30429.1 - 0.16 12.2 2.4 0.54 10.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4030) Rad51 PF08423.11 VBB30430.1 - 7.5e-127 421.9 0.1 9.3e-127 421.6 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 VBB30430.1 - 4.5e-10 39.4 0.0 6.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 VBB30430.1 - 1.1e-09 38.7 0.2 2.9e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.21 VBB30430.1 - 1.2e-09 38.0 0.1 2e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 VBB30430.1 - 0.00027 20.3 1.3 0.0079 15.6 0.1 2.6 3 0 0 3 3 3 1 KaiC PAXNEB PF05625.11 VBB30430.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein AAA_24 PF13479.6 VBB30430.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 VBB30430.1 - 0.13 12.5 0.5 0.99 9.7 0.5 2.2 1 1 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.6 VBB30431.1 - 2.8e-07 31.1 0.0 3.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 VBB30431.1 - 7.8e-05 22.7 0.0 0.00022 21.3 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Tetraspanin PF00335.20 VBB30432.1 - 1.4e-34 119.8 13.3 1.7e-34 119.6 13.3 1.1 1 0 0 1 1 1 1 Tetraspanin family KASH_CCD PF14662.6 VBB30433.1 - 4.3 7.1 56.5 0.54 10.1 25.6 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Ion_trans PF00520.31 VBB30434.1 - 1.1e-26 93.6 2.1 1.3e-26 93.4 2.1 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 VBB30434.1 - 7.4e-15 54.7 4.0 1.2e-14 54.0 4.0 1.3 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.12 VBB30434.1 - 0.041 12.6 1.3 0.047 12.4 1.3 1.1 1 0 0 1 1 1 0 Polycystin cation channel Pkinase_Tyr PF07714.17 VBB30435.1 - 3e-55 187.3 0.0 4.7e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 VBB30435.1 - 3.5e-52 174.9 13.5 6.5e-14 52.3 0.1 6.5 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Pkinase PF00069.25 VBB30435.1 - 1.7e-46 158.7 0.0 3.5e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 VBB30435.1 - 5.6e-42 141.6 6.8 4e-09 36.8 0.0 7.6 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30435.1 - 2.1e-39 129.0 10.7 0.00083 19.6 0.0 10.2 10 0 0 10 10 9 8 Ankyrin repeat Ank PF00023.30 VBB30435.1 - 4.4e-39 131.2 17.2 7.1e-06 26.2 0.2 10.3 11 0 0 11 11 9 8 Ankyrin repeat Ank_5 PF13857.6 VBB30435.1 - 1e-35 121.3 8.4 0.00011 22.5 0.1 9.2 2 1 7 9 9 9 6 Ankyrin repeats (many copies) Kdo PF06293.14 VBB30435.1 - 0.00022 20.6 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB30435.1 - 0.00036 20.5 0.2 0.002 18.1 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB30435.1 - 0.016 14.8 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 VBB30435.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 VBB30435.1 - 0.63 8.9 0.0 0.63 8.9 0.0 2.3 3 0 0 3 3 3 0 Haspin like kinase domain Myb_DNA-bind_5 PF13873.6 VBB30436.1 - 1.8e-07 31.1 3.5 0.0024 17.9 0.2 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 VBB30436.1 - 5.6e-05 23.4 1.4 0.054 13.8 0.0 2.8 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4294 PF14127.6 VBB30436.1 - 0.017 15.0 5.2 0.55 10.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4294) SipA PF09052.10 VBB30436.1 - 0.035 13.7 2.1 0.061 12.9 0.0 2.4 3 0 0 3 3 3 0 SipA N-terminal domain Ribosomal_60s PF00428.19 VBB30436.1 - 1 10.0 10.2 5.6 7.6 0.2 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein eIF3_p135 PF12807.7 VBB30436.1 - 2.9 7.9 8.6 6.5 6.7 0.1 3.1 2 1 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 WD40 PF00400.32 VBB30437.1 - 6.1e-12 45.9 8.3 0.012 16.5 0.0 6.2 6 1 0 6 6 5 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 VBB30437.1 - 3.9e-11 42.6 9.0 3.9e-11 42.6 9.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB30437.1 - 9.2e-11 41.6 9.2 9.2e-11 41.6 9.2 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB30437.1 - 1.5e-08 34.3 9.0 1.5e-08 34.3 9.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB30437.1 - 2.7e-08 34.0 9.8 2.7e-08 34.0 9.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 VBB30437.1 - 1.2e-07 31.7 11.0 1.2e-07 31.7 11.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 VBB30437.1 - 1.4e-07 31.3 8.6 1.4e-07 31.3 8.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB30437.1 - 4.4e-06 26.5 5.5 4.4e-06 26.5 5.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 VBB30437.1 - 1.8e-05 24.4 7.2 1.8e-05 24.4 5.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit ANAPC4_WD40 PF12894.7 VBB30437.1 - 0.00014 22.1 0.1 1.7 9.0 0.1 4.0 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB30437.1 - 0.0017 17.7 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 VBB30437.1 - 0.0028 17.6 0.0 0.18 11.6 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 VBB30437.1 - 0.0028 16.4 1.5 0.017 13.8 0.1 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 zf-RING_10 PF16685.5 VBB30437.1 - 0.0065 16.6 6.0 0.019 15.1 5.2 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 VBB30437.1 - 0.015 15.5 12.2 0.044 14.1 7.9 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain DUF2968 PF11180.8 VBB30437.1 - 0.019 14.6 0.3 0.034 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) U-box PF04564.15 VBB30437.1 - 0.097 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.6 VBB30437.1 - 0.12 12.2 16.7 0.043 13.7 10.4 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 VBB30437.1 - 0.21 11.6 6.8 0.59 10.2 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 VBB30437.1 - 1.1 9.1 11.8 0.12 12.3 6.4 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.21 VBB30437.1 - 3.2 8.0 7.1 0.9 9.7 1.9 2.5 2 0 0 2 2 2 0 FYVE zinc finger Rad50_zn_hook PF04423.14 VBB30437.1 - 9 6.2 7.3 0.51 10.2 0.3 2.6 3 0 0 3 3 2 0 Rad50 zinc hook motif Pkinase PF00069.25 VBB30438.1 - 3e-34 118.6 0.0 5.2e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PTEN_C2 PF10409.9 VBB30438.1 - 2.5e-17 62.9 0.0 4.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Pkinase_Tyr PF07714.17 VBB30438.1 - 1.4e-14 54.0 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 VBB30438.1 - 1.9e-06 27.9 0.0 5.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Haspin_kinase PF12330.8 VBB30438.1 - 0.0005 19.1 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 VBB30438.1 - 0.00086 18.5 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 VBB30438.1 - 0.0043 17.0 0.0 0.14 12.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB30438.1 - 0.01 15.2 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like ANAPC_CDC26 PF10471.9 VBB30439.1 - 0.029 15.2 1.9 0.036 14.9 1.9 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Calreticulin PF00262.18 VBB30441.1 - 3.5e-44 151.2 25.2 1.5e-20 73.4 10.0 4.0 2 1 2 4 4 4 3 Calreticulin family Neur_chan_memb PF02932.16 VBB30441.1 - 0.35 10.9 1.2 0.39 10.7 1.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 VBB30441.1 - 3.6 6.3 16.0 4.5 6.0 16.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DDHD PF02862.17 VBB30441.1 - 5 7.2 7.0 7.6 6.6 7.0 1.3 1 0 0 1 1 1 0 DDHD domain Calreticulin PF00262.18 VBB30442.1 - 1.8e-84 283.8 22.3 1.3e-64 218.4 9.8 2.5 2 1 1 3 3 3 2 Calreticulin family MDM10 PF12519.8 VBB30442.1 - 0.15 10.9 7.7 0.21 10.4 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AIF_C PF14721.6 VBB30442.1 - 1.4 9.3 6.5 3.1 8.2 6.5 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CCDC71L PF15374.6 VBB30442.1 - 3.3 6.9 9.2 4.7 6.4 9.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L UcrQ PF02939.16 VBB30443.1 - 3.1e-20 71.9 0.5 4e-20 71.5 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 VBB30443.1 - 0.0059 17.0 0.8 0.0076 16.6 0.1 1.6 2 0 0 2 2 2 1 Cytochrome b-c1 complex subunit 8 Glycoamylase PF10091.9 VBB30443.1 - 0.044 13.4 0.1 0.05 13.2 0.1 1.0 1 0 0 1 1 1 0 Putative glucoamylase SET PF00856.28 VBB30444.1 - 7.7e-09 36.1 0.0 5.1e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 SET domain Abhydrolase_6 PF12697.7 VBB30446.1 - 2.3e-23 84.0 0.0 2.8e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 VBB30446.1 - 1.2e-11 44.8 0.2 1.9e-10 40.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB30446.1 - 1.4e-08 34.3 0.2 2e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 VBB30446.1 - 0.0048 17.0 0.0 0.0079 16.3 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 VBB30446.1 - 0.027 14.1 0.5 0.33 10.5 0.4 2.5 2 1 0 2 2 2 0 Putative esterase Ser_hydrolase PF06821.13 VBB30446.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.13 VBB30446.1 - 0.049 13.5 0.8 0.28 11.0 0.8 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 VBB30446.1 - 0.093 12.4 0.3 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 VBB30446.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 VBB30446.1 - 0.18 11.6 2.0 1.4 8.7 1.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase RNA_pol_L_2 PF13656.6 VBB30450.1 - 3.7e-29 100.3 0.2 1.4e-28 98.5 0.1 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 VBB30450.1 - 4.1e-11 42.1 0.0 1e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Iwr1 PF08574.10 VBB30450.1 - 3.9e-10 40.6 6.3 3.9e-10 40.6 6.3 1.8 2 0 0 2 2 2 1 Transcription factor Iwr1 DUF3275 PF11679.8 VBB30450.1 - 0.029 14.3 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) LIM PF00412.22 VBB30451.1 - 2.8e-13 49.9 12.1 4e-13 49.4 12.1 1.2 1 0 0 1 1 1 1 LIM domain Homeodomain PF00046.29 VBB30452.1 - 2.1e-17 62.7 7.2 3.2e-17 62.1 7.2 1.3 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 VBB30452.1 - 5.4e-11 42.6 6.5 5.6e-11 42.5 4.8 1.9 1 1 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 VBB30452.1 - 5.7e-06 26.1 0.2 1.1e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain NOA36 PF06524.12 VBB30452.1 - 0.0043 16.4 5.0 0.0043 16.4 5.0 2.0 2 0 0 2 2 2 1 NOA36 protein B9-C2 PF07162.11 VBB30453.1 - 1.8e-37 129.1 0.0 2.5e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ribosomal_L19e PF01280.20 VBB30454.1 - 1e-62 210.5 12.3 1e-62 210.5 12.3 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e ENT PF03735.14 VBB30455.1 - 4.8e-20 71.4 0.2 9.6e-20 70.4 0.2 1.5 1 0 0 1 1 1 1 ENT domain Cadherin_C_2 PF16492.5 VBB30456.1 - 0.007 17.1 0.1 0.025 15.3 0.1 1.9 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal HI0933_like PF03486.14 VBB30456.1 - 0.025 13.3 0.7 0.041 12.6 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein Acyltransferase PF01553.21 VBB30457.1 - 1.4e-12 47.4 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Nipped-B_C PF12830.7 VBB30457.1 - 0.036 14.0 0.3 0.073 13.0 0.0 1.6 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus EMC3_TMCO1 PF01956.16 VBB30457.1 - 0.23 11.2 2.4 1.3 8.8 0.4 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Pkinase PF00069.25 VBB30458.1 - 1.3e-43 149.3 0.0 8.7e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30458.1 - 4.3e-22 78.6 0.1 5.3e-18 65.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB30458.1 - 1.8e-05 23.7 0.0 2.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB30458.1 - 0.00014 21.9 0.0 0.0078 16.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 VBB30458.1 - 0.0024 17.5 0.0 0.027 14.1 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 VBB30458.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 VBB30458.1 - 0.0035 16.7 0.2 0.0067 15.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB30458.1 - 0.0081 15.5 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like LTP_2 PF14368.6 VBB30458.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 Probable lipid transfer zf-Paramyx-P PF13008.7 VBB30458.1 - 4.9 6.7 11.6 0.27 10.7 5.6 2.0 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Ribosomal_L28e PF01778.17 VBB30459.1 - 2.7e-22 79.7 7.4 1.4e-16 61.3 0.2 2.1 2 0 0 2 2 2 2 Ribosomal L28e protein family Tctex-1 PF03645.13 VBB30460.1 - 9.9e-22 77.1 0.1 2.3e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Tctex-1 family PGM_PMM_I PF02878.16 VBB30461.1 - 1.2e-34 119.0 0.0 2e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I WD40 PF00400.32 VBB30461.1 - 1.9e-09 38.0 16.7 0.00098 19.9 0.1 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30461.1 - 3.8e-05 23.9 2.0 0.25 11.6 0.0 4.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB30461.1 - 0.0017 17.4 0.5 0.19 10.7 0.0 3.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nebulin PF00880.18 VBB30462.1 - 4.4e-18 64.8 3.7 1.4e-10 40.9 0.2 2.6 2 0 0 2 2 2 2 Nebulin repeat SH3_1 PF00018.28 VBB30462.1 - 7.7e-15 54.2 0.1 1.5e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB30462.1 - 2.9e-13 49.4 0.1 5.8e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain LIM PF00412.22 VBB30462.1 - 3e-11 43.4 5.7 5.4e-11 42.6 5.7 1.5 1 0 0 1 1 1 1 LIM domain SH3_2 PF07653.17 VBB30462.1 - 0.0012 18.4 0.0 0.0032 17.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF3029 PF11230.8 VBB30462.1 - 0.088 11.2 0.1 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Cation_ATPase_C PF00689.21 VBB30464.1 - 2.7e-38 131.5 6.3 2.7e-38 131.5 6.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 VBB30464.1 - 1.7e-33 115.7 0.9 1.7e-33 115.7 0.9 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 VBB30464.1 - 1.1e-17 63.9 0.1 2.4e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 VBB30464.1 - 5.5e-15 56.2 0.0 5.1e-13 49.8 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB30464.1 - 0.022 15.2 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 VBB30464.1 - 0.076 12.7 0.3 11 5.7 0.1 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase SPC12 PF06645.13 VBB30464.1 - 7.8 6.7 9.0 0.66 10.1 3.0 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SpoIIM PF01944.17 VBB30464.1 - 8.5 6.4 17.2 0.29 11.2 0.8 3.0 3 0 0 3 3 3 0 Stage II sporulation protein M DSPc PF00782.20 VBB30465.1 - 2.6e-28 98.5 0.1 3.9e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB30465.1 - 6.3e-05 22.6 0.0 9.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 VBB30465.1 - 0.073 13.4 1.9 0.084 13.2 0.4 1.8 2 1 0 2 2 2 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 VBB30465.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M23 PF01551.22 VBB30466.1 - 7.7e-11 42.1 0.0 2.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M23 UAA PF08449.11 VBB30467.1 - 6.3e-56 189.8 21.3 9e-56 189.3 21.3 1.2 1 0 0 1 1 1 1 UAA transporter family WD40 PF00400.32 VBB30467.1 - 1.8e-28 98.2 18.2 6e-06 26.9 0.0 9.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30467.1 - 4.1e-24 84.7 0.2 0.00013 22.2 0.1 8.8 4 3 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 VBB30467.1 - 4.4e-16 59.1 1.8 1.2e-15 57.8 1.8 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family EamA PF00892.20 VBB30467.1 - 1.4e-11 44.7 17.4 4.9e-07 30.0 11.4 2.6 2 0 0 2 2 2 2 EamA-like transporter family Ge1_WD40 PF16529.5 VBB30467.1 - 5.8e-08 32.1 5.3 0.0031 16.5 0.1 6.3 4 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPT PF03151.16 VBB30467.1 - 3.8e-07 29.7 11.1 8.9e-07 28.5 11.1 1.6 1 0 0 1 1 1 1 Triose-phosphate Transporter family Gmad1 PF10647.9 VBB30467.1 - 1.2e-06 28.5 0.4 0.0039 17.0 0.0 3.2 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 VBB30467.1 - 1.2e-06 27.5 6.8 0.00096 17.9 0.1 3.6 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.11 VBB30467.1 - 3.5e-06 27.0 1.0 0.002 18.0 0.2 4.5 4 3 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 VBB30467.1 - 0.00033 20.1 0.0 0.0021 17.5 0.0 2.4 2 1 0 2 2 2 1 WD40-like domain SLC35F PF06027.12 VBB30467.1 - 0.00036 20.1 13.3 0.00036 20.1 13.3 1.9 2 0 0 2 2 2 1 Solute carrier family 35 PD40 PF07676.12 VBB30467.1 - 0.015 15.2 0.1 17 5.5 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Utp21 PF04192.12 VBB30467.1 - 0.066 12.7 1.3 0.12 11.9 1.3 1.4 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Utp13 PF08625.11 VBB30467.1 - 0.31 11.0 7.5 1.3 8.9 7.5 2.1 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Clc-like PF07062.12 VBB30469.1 - 1.4e-70 237.1 7.5 1.7e-70 236.8 7.5 1.1 1 0 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 VBB30469.1 - 8.9e-07 28.8 3.5 1.2e-06 28.4 3.0 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 VBB30469.1 - 0.019 14.6 16.0 0.2 11.3 16.9 2.1 1 1 1 2 2 2 0 SUR7/PalI family ELH PF02323.15 VBB30469.1 - 0.065 12.6 0.2 7.9 5.8 0.4 2.2 2 0 0 2 2 2 0 Egg-laying hormone precursor Phage_holin_Dp1 PF16938.5 VBB30469.1 - 0.15 12.3 0.3 0.15 12.3 0.3 2.5 1 1 1 2 2 2 0 Putative phage holin Dp-1 Orai-1 PF07856.12 VBB30469.1 - 9.8 5.8 10.9 3.6 7.3 3.2 2.9 1 1 1 2 2 2 0 Mediator of CRAC channel activity B9-C2 PF07162.11 VBB30471.1 - 3.4e-51 173.8 0.1 3.9e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Thioredoxin_6 PF13848.6 VBB30472.1 - 8e-42 143.2 5.2 3.6e-41 141.1 1.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 VBB30472.1 - 2e-16 59.8 0.3 5.6e-16 58.4 0.3 1.8 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 VBB30472.1 - 1.3e-05 24.5 0.9 2.2e-05 23.7 0.2 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 VBB30472.1 - 3.4e-05 24.2 1.3 0.00021 21.7 0.2 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 VBB30472.1 - 0.065 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin DUF2972 PF11186.8 VBB30472.1 - 0.077 12.9 1.4 0.46 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2972) TFIIA PF03153.13 VBB30473.1 - 2.1 8.2 13.4 2.6 7.9 13.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_head PF00063.21 VBB30474.1 - 2.5e-296 984.4 2.1 2.5e-296 984.4 2.1 3.0 5 0 0 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 VBB30474.1 - 6.9e-273 908.3 304.2 8.4e-273 908.0 304.2 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 VBB30474.1 - 7.8e-14 51.2 0.1 2.3e-13 49.7 0.1 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 VBB30474.1 - 0.13 12.5 0.0 0.13 12.5 0.0 5.6 5 3 0 5 5 5 0 AAA domain IQ PF00612.27 VBB30474.1 - 0.85 9.6 6.7 0.052 13.4 0.8 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif PTPLA PF04387.14 VBB30475.1 - 2.4e-50 170.5 11.5 3.5e-50 170.0 11.5 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CRAL_TRIO PF00650.20 VBB30476.1 - 1.9e-17 63.5 0.0 3.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 VBB30476.1 - 0.066 13.4 0.4 0.14 12.3 0.4 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Glyco_hydro_30 PF02055.16 VBB30477.1 - 1e-133 445.6 3.8 3.4e-100 335.4 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 VBB30477.1 - 1.5e-08 34.7 0.0 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 VBB30477.1 - 0.0038 16.5 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 UL21a PF17636.2 VBB30477.1 - 0.0088 16.1 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Viral Unique Long protein 21a Cation_ATPase_C PF00689.21 VBB30480.1 - 6.2e-43 146.6 10.5 9.1e-43 146.1 7.8 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 VBB30480.1 - 9.2e-31 106.8 19.4 4.9e-25 88.1 1.2 3.2 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 VBB30480.1 - 3.5e-19 68.2 0.0 5.6e-17 61.2 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 VBB30480.1 - 6.4e-17 62.5 0.0 3.7e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 VBB30480.1 - 1.9e-16 59.9 0.0 5.4e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ATP_Ca_trans_C PF12424.8 VBB30480.1 - 1.1e-13 51.4 0.2 1.1e-13 51.4 0.2 2.7 3 0 0 3 3 3 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 VBB30480.1 - 4.4e-06 26.6 3.3 0.00013 21.8 0.4 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 VBB30480.1 - 1 9.9 6.4 8.1 7.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ATP_Ca_trans_C PF12424.8 VBB30481.1 - 0.00024 21.5 0.1 0.00031 21.2 0.1 1.4 1 1 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal VWA_2 PF13519.6 VBB30482.1 - 2.2e-25 89.4 0.0 8.9e-25 87.4 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 VBB30482.1 - 8.8e-12 45.2 0.2 1.5e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 VBB30482.1 - 3.3e-08 34.0 0.1 6.5e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 VBB30482.1 - 9.8e-07 28.3 13.7 0.0003 20.5 1.6 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif Fer4_14 PF13394.6 VBB30482.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain RAP80_UIM PF18282.1 VBB30482.1 - 0.011 15.5 1.0 0.19 11.6 0.5 2.6 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif RPN13_C PF16550.5 VBB30482.1 - 0.021 15.0 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 UCH-binding domain YjeF_N PF03853.15 VBB30482.1 - 0.043 13.7 0.5 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus Hydant_A_N PF05378.13 VBB30482.1 - 0.082 12.6 1.0 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region PDCD9 PF07147.12 VBB30483.1 - 2.3e-67 228.2 0.0 5.4e-67 226.9 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) UCH PF00443.29 VBB30484.1 - 7.4e-32 110.8 0.0 1.1e-30 107.1 0.0 2.4 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 VBB30484.1 - 7.8e-06 25.6 1.6 2.7e-05 23.8 0.1 2.6 4 0 0 4 4 4 1 Ubiquitin family UCH_1 PF13423.6 VBB30484.1 - 1e-05 25.3 0.0 1e-05 25.3 0.0 5.2 4 2 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 VBB30484.1 - 0.072 13.6 0.6 0.4 11.2 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-like domain TBK1_ULD PF18396.1 VBB30484.1 - 0.14 12.1 2.0 13 5.8 0.6 2.6 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain zf-C3HC PF07967.13 VBB30484.1 - 0.17 11.9 10.1 0.058 13.4 1.7 3.5 3 1 0 3 3 3 0 C3HC zinc finger-like DUF585 PF04522.12 VBB30484.1 - 0.32 10.6 4.0 5.6 6.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF585) SNRNP27 PF08648.12 VBB30485.1 - 2.9e-28 97.7 0.5 6.7e-28 96.5 0.5 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Presenilin PF01080.17 VBB30485.1 - 9.3 4.9 10.5 9.9 4.8 10.5 1.0 1 0 0 1 1 1 0 Presenilin RhoGEF PF00621.20 VBB30486.1 - 5.9e-23 82.0 0.9 2.3e-22 80.1 0.9 2.1 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 VBB30486.1 - 0.0004 20.9 1.6 0.00073 20.0 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_10 PF15411.6 VBB30486.1 - 0.0023 18.2 1.1 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 VBB30486.1 - 0.028 14.4 1.2 0.078 13.0 0.2 2.3 2 1 0 2 2 2 0 PH domain Mucin PF01456.17 VBB30486.1 - 0.042 13.8 37.9 0.12 12.4 37.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 VBB30486.1 - 2.9 5.9 19.9 7 4.7 19.9 1.6 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_S9_N PF02897.15 VBB30487.1 - 1.8e-100 336.6 1.1 2.1e-100 336.5 1.1 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4931 PF16285.5 VBB30487.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) betaPIX_CC PF16523.5 VBB30488.1 - 3.2e-33 113.4 8.5 5.3e-33 112.7 8.5 1.4 1 0 0 1 1 1 1 betaPIX coiled coil CCDC144C PF14915.6 VBB30488.1 - 0.001 18.2 5.1 0.0016 17.6 5.1 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CREPT PF16566.5 VBB30488.1 - 0.0045 17.2 4.6 0.0045 17.2 4.6 1.7 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour GlutR_dimer PF00745.20 VBB30488.1 - 0.0087 16.5 2.5 0.018 15.5 2.5 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain RhoGEF67_u2 PF16614.5 VBB30488.1 - 0.046 13.8 0.9 1.2 9.2 0.1 2.7 2 1 1 3 3 3 0 Unstructured region two on RhoGEF 6 and 7 OmpH PF03938.14 VBB30488.1 - 0.092 13.1 5.6 0.15 12.4 5.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 VBB30488.1 - 0.1 12.6 4.5 0.17 11.9 4.5 1.3 1 0 0 1 1 1 0 Laminin Domain II ABC_tran_Xtn PF12848.7 VBB30488.1 - 0.2 11.7 4.0 0.52 10.4 4.0 1.6 1 0 0 1 1 1 0 ABC transporter FlxA PF14282.6 VBB30488.1 - 0.41 10.6 10.0 0.85 9.6 10.0 1.5 1 0 0 1 1 1 0 FlxA-like protein YabA PF06156.13 VBB30488.1 - 0.59 10.8 4.7 1.4 9.6 4.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA SH3_9 PF14604.6 VBB30489.1 - 4.7e-16 58.4 0.0 8.3e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.20 VBB30489.1 - 7.8e-15 55.6 0.2 1.4e-14 54.7 0.0 1.5 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 VBB30489.1 - 1.6e-13 50.0 0.1 2.9e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB30489.1 - 2.6e-12 46.2 0.0 4.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3369 PF11849.8 VBB30489.1 - 0.018 15.3 0.6 0.089 13.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) TSP_1 PF00090.19 VBB30490.1 - 1.8e-77 255.4 181.0 2.1e-10 40.6 8.3 12.5 12 1 0 12 12 12 10 Thrombospondin type 1 domain RhoGAP PF00620.27 VBB30491.1 - 3.9e-43 146.9 1.7 6.2e-43 146.2 0.3 1.9 1 1 1 2 2 2 1 RhoGAP domain C1_1 PF00130.22 VBB30491.1 - 3.3e-12 46.1 10.0 7.4e-12 45.0 10.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 VBB30491.1 - 1.5e-11 44.2 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Creb_binding PF09030.10 VBB30491.1 - 0.21 12.3 1.2 0.49 11.1 1.2 1.6 1 1 0 1 1 1 0 Creb binding EF1_GNE PF00736.19 VBB30492.1 - 4.9e-30 103.5 1.4 4.9e-30 103.5 1.4 2.5 3 0 0 3 3 3 1 EF-1 guanine nucleotide exchange domain RTP1_C1 PF10363.9 VBB30492.1 - 2.3e-19 69.7 2.1 4.2e-19 68.8 0.4 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 VBB30492.1 - 1.3e-08 34.4 1.8 4.8e-08 32.5 1.8 2.1 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 EF-1_beta_acid PF10587.9 VBB30492.1 - 8.5e-06 26.1 8.0 8.5e-06 26.1 8.0 3.1 3 1 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region HEAT_2 PF13646.6 VBB30492.1 - 0.024 15.0 4.4 2.4 8.6 0.0 3.7 3 1 1 4 4 4 0 HEAT repeats Cnd1 PF12717.7 VBB30492.1 - 0.19 11.8 6.0 0.65 10.0 0.1 4.0 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 VBB30492.1 - 1.7 9.1 4.3 61 4.3 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Sugar_tr PF00083.24 VBB30493.1 - 1e-33 116.9 24.4 1.4e-33 116.5 24.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB30493.1 - 2.7e-17 62.7 31.2 2.2e-16 59.7 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1356 PF07092.12 VBB30493.1 - 0.11 11.7 2.0 0.45 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Deltameth_res PF16020.5 VBB30493.1 - 5.7 6.9 8.2 5.7 6.9 0.1 4.1 3 1 1 4 4 4 0 Deltamethrin resistance RRM_5 PF13893.6 VBB30494.1 - 3.4e-42 143.0 0.3 3.2e-37 126.9 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FbpA PF05833.11 VBB30494.1 - 3.8e-38 131.4 9.8 3.8e-38 131.4 9.8 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 VBB30494.1 - 1.9e-31 108.9 0.0 1.9e-31 108.9 0.0 2.8 4 0 0 4 4 4 1 NFACT protein RNA binding domain NFACT-C PF11923.8 VBB30494.1 - 8.2e-22 77.1 0.0 8.2e-22 77.1 0.0 3.0 4 0 0 4 4 4 1 NFACT protein C-terminal domain RRM_1 PF00076.22 VBB30494.1 - 1.1e-21 76.4 0.0 3.1e-08 33.3 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 VBB30494.1 - 2.6e-10 40.3 0.0 6.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 VBB30494.1 - 0.0019 18.1 0.0 0.36 10.7 0.1 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4523 PF15023.6 VBB30494.1 - 0.0031 17.4 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) GAT PF03127.14 VBB30494.1 - 0.25 11.7 4.7 0.16 12.3 1.3 2.4 2 0 0 2 2 2 0 GAT domain Nas2_N PF18265.1 VBB30495.1 - 1.7e-23 82.3 0.5 3e-23 81.5 0.5 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain BAF PF02961.14 VBB30495.1 - 1.7e-15 57.2 0.4 2.9e-15 56.5 0.0 1.5 2 0 0 2 2 2 1 Barrier to autointegration factor PDZ_6 PF17820.1 VBB30495.1 - 3.5e-05 23.6 0.0 0.00016 21.4 0.0 2.2 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB30495.1 - 0.00014 22.1 0.2 0.0011 19.3 0.0 2.5 2 2 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 VBB30495.1 - 0.0021 18.4 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 VBB30495.1 - 0.019 15.3 0.1 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 PDZ domain HHH_5 PF14520.6 VBB30495.1 - 0.059 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Mito_carr PF00153.27 VBB30496.1 - 3.2e-60 200.1 0.0 2.1e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein VWA PF00092.28 VBB30498.1 - 2.3e-10 41.0 0.5 2.9e-10 40.7 0.5 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 VBB30498.1 - 0.00078 20.1 0.0 0.0013 19.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ldl_recept_a PF00057.18 VBB30499.1 - 1.5e-172 559.5 387.9 1.9e-12 47.2 16.2 23.1 22 0 0 22 22 22 21 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 VBB30499.1 - 1.1e-43 147.4 9.1 2.3e-08 34.3 0.1 11.0 11 0 0 11 11 11 9 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 VBB30499.1 - 2.5e-17 62.8 64.5 5.9e-10 39.3 8.1 13.6 14 2 1 15 15 15 7 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 VBB30499.1 - 6e-11 42.4 20.6 3.1e-07 30.5 7.0 23.4 22 6 5 27 27 27 4 Calcium-binding EGF domain cEGF PF12662.7 VBB30499.1 - 1.1e-06 28.4 19.6 6.1e-05 22.9 6.3 9.4 8 0 0 8 8 8 4 Complement Clr-like EGF-like FH2 PF02181.23 VBB30500.1 - 6.3e-34 117.7 0.1 8.9e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Syja_N PF02383.18 VBB30502.1 - 2.5e-57 194.6 0.3 1.4e-49 169.1 0.1 2.2 1 1 1 2 2 2 2 SacI homology domain MH2 PF03166.14 VBB30503.1 - 3.3e-53 180.7 0.1 3.3e-53 180.7 0.1 2.0 2 0 0 2 2 2 1 MH2 domain MH1 PF03165.16 VBB30503.1 - 2.6e-35 120.8 0.9 8e-35 119.2 0.1 2.2 2 0 0 2 2 2 1 MH1 domain DUF1955 PF09205.10 VBB30503.1 - 9.3e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1955) PAT1 PF09770.9 VBB30503.1 - 3.7 5.7 20.3 5.5 5.1 20.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 VBB30503.1 - 5.8 6.8 21.3 0.6 10.1 16.6 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L28e PF01778.17 VBB30504.1 - 6.2e-30 104.3 0.1 6.2e-30 104.3 0.1 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 VBB30504.1 - 9.9e-26 90.3 11.6 9.9e-26 90.3 11.6 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region RRN3 PF05327.11 VBB30504.1 - 5.9 5.3 14.7 11 4.5 14.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 VBB30505.1 - 5.6e-97 325.6 6.0 3.7e-86 289.9 4.5 3.0 1 1 1 2 2 2 2 CDC45-like protein LAP1C PF05609.12 VBB30505.1 - 0.1 11.7 6.0 0.17 10.9 6.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CCSAP PF15748.5 VBB30505.1 - 0.3 11.2 10.8 0.43 10.7 10.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RAP1 PF07218.11 VBB30505.1 - 0.68 8.1 5.5 1 7.6 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BTB PF00651.31 VBB30506.1 - 1.3e-10 41.5 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 VBB30506.1 - 2.9e-06 27.3 0.1 6.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch STAS PF01740.21 VBB30506.1 - 0.15 11.7 0.1 0.56 9.9 0.0 1.9 3 0 0 3 3 3 0 STAS domain IGFL PF14653.6 VBB30506.1 - 0.17 11.8 1.8 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 Insulin growth factor-like family PAF-AH_p_II PF03403.13 VBB30507.1 - 2e-104 349.1 0.0 2.6e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 VBB30507.1 - 1.5e-11 43.7 0.0 8.9e-07 28.1 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 VBB30507.1 - 1.5e-08 34.1 0.0 0.0059 15.7 0.0 2.6 3 0 0 3 3 3 2 Chlorophyllase DLH PF01738.18 VBB30507.1 - 2e-06 27.5 0.0 7.7e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 VBB30507.1 - 6.9e-06 25.5 0.2 0.00043 19.6 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 VBB30507.1 - 5.9e-05 22.6 0.1 0.00026 20.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 VBB30507.1 - 7.9e-05 22.4 0.0 0.00015 21.5 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 VBB30507.1 - 0.00064 19.4 0.1 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 VBB30507.1 - 0.0038 17.1 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 VBB30507.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 VBB30507.1 - 0.0041 16.7 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 VBB30507.1 - 0.0048 17.5 0.0 0.0086 16.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 VBB30507.1 - 0.014 15.2 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 VBB30507.1 - 0.024 13.3 0.0 0.15 10.7 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 VBB30507.1 - 0.033 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 VBB30507.1 - 0.1 12.4 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Gemin7 PF11095.8 VBB30508.1 - 7.5e-26 89.8 0.1 9.3e-26 89.5 0.1 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) DUF2052 PF09747.9 VBB30508.1 - 0.093 12.8 0.6 0.12 12.5 0.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ribosomal_L23eN PF03939.13 VBB30509.1 - 3.6e-20 71.9 9.9 7.8e-20 70.8 9.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 VBB30509.1 - 7.3e-17 61.5 6.6 1.2e-16 60.9 3.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 ABC_tran PF00005.27 VBB30509.1 - 0.086 13.4 0.1 0.096 13.2 0.1 1.2 1 0 0 1 1 1 0 ABC transporter COesterase PF00135.28 VBB30510.1 - 9e-140 466.9 0.0 1.1e-139 466.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 VBB30510.1 - 1.2e-05 26.1 1.4 4.4e-05 24.2 0.2 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 VBB30510.1 - 4.9e-05 22.9 0.4 8.7e-05 22.1 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 VBB30510.1 - 0.00011 22.2 0.3 0.00039 20.3 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold AAA_12 PF13087.6 VBB30511.1 - 5.9e-34 117.4 1.5 8e-34 117.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 VBB30511.1 - 5.2e-26 92.0 0.0 1.8e-25 90.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 VBB30511.1 - 3.2e-08 34.0 0.0 1.3e-06 28.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 VBB30511.1 - 4.8e-07 29.7 0.0 0.00083 19.1 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 VBB30511.1 - 0.0025 18.2 0.1 0.12 12.8 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB30511.1 - 0.012 15.9 0.0 0.16 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 VBB30511.1 - 0.031 14.6 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 VBB30511.1 - 0.064 13.0 0.0 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 VBB30511.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DNApol_Exo PF18136.1 VBB30512.1 - 1.2e-15 57.5 0.0 1.5e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain Alpha-2-MRAP_N PF06400.11 VBB30512.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain TRAPP PF04051.16 VBB30513.1 - 1.4e-34 118.9 0.0 1.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Maelstrom PF13017.6 VBB30514.1 - 8e-07 28.9 2.2 2.5e-06 27.3 2.2 1.8 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 VBB30514.1 - 0.026 15.1 1.7 0.12 13.0 1.2 2.4 2 0 0 2 2 2 0 HMG-box domain DUF3106 PF11304.8 VBB30514.1 - 1.2 9.6 8.3 5.4 7.5 6.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) zinc_ribbon_9 PF14369.6 VBB30515.1 - 0.16 12.3 2.4 1.2 9.5 1.0 2.9 2 0 0 2 2 2 0 zinc-ribbon CUB PF00431.20 VBB30517.1 - 2.2e-09 37.6 0.0 3.5e-07 30.5 0.0 2.9 2 1 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 VBB30517.1 - 3.7e-09 36.7 3.1 1.2e-08 35.0 3.1 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Sarcoglycan_1 PF04790.13 VBB30519.1 - 3.3e-40 138.1 0.1 3.6e-40 138.0 0.1 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF3081 PF11280.8 VBB30519.1 - 0.18 11.6 0.8 0.4 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) PINIT PF14324.6 VBB30521.1 - 5e-24 85.3 0.1 1.1e-23 84.1 0.1 1.7 1 0 0 1 1 1 1 PINIT domain Oxidored_q6 PF01058.22 VBB30521.1 - 2.5e-23 82.4 0.1 9.1e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit zf-MIZ PF02891.20 VBB30521.1 - 5.4e-20 70.9 1.3 5.4e-20 70.9 1.3 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 VBB30521.1 - 3.4e-05 23.6 0.4 0.00011 21.9 0.4 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit MRNIP PF15749.5 VBB30521.1 - 0.028 15.1 0.0 0.071 13.8 0.0 1.7 1 0 0 1 1 1 0 MRN-interacting protein Brix PF04427.18 VBB30522.1 - 3e-40 138.4 0.4 3e-40 138.4 0.4 1.9 2 0 0 2 2 2 1 Brix domain LIM PF00412.22 VBB30523.1 - 8.6e-55 182.8 72.7 5.2e-12 45.8 9.9 5.1 5 0 0 5 5 5 5 LIM domain Trypan_PARP PF05887.11 VBB30524.1 - 0.35 10.8 7.9 0.46 10.5 7.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Dynactin PF12455.8 VBB30526.1 - 8.3e-48 163.1 0.4 8.3e-48 163.1 0.4 4.8 3 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 VBB30526.1 - 2e-24 85.4 0.7 3.6e-24 84.5 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain bZIP_1 PF00170.21 VBB30526.1 - 0.0066 16.5 4.9 0.0066 16.5 4.9 10.8 8 3 4 13 13 13 2 bZIP transcription factor MbeD_MobD PF04899.12 VBB30526.1 - 0.0068 16.5 2.4 0.0068 16.5 2.4 5.2 5 1 0 5 5 5 1 MbeD/MobD like YabA PF06156.13 VBB30526.1 - 0.01 16.4 7.6 0.01 16.4 7.6 8.6 3 2 3 7 7 7 0 Initiation control protein YabA Lant_dehydr_C PF14028.6 VBB30526.1 - 1.9 7.9 9.5 0.14 11.7 0.4 2.8 2 1 1 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term Tex_YqgF PF16921.5 VBB30527.1 - 4.3e-37 127.4 0.0 1.1e-36 126.1 0.0 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain Tex_N PF09371.10 VBB30527.1 - 1.1e-25 90.4 0.2 3e-25 89.0 0.2 1.8 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 VBB30527.1 - 4.6e-24 84.4 0.1 2e-23 82.4 0.1 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 VBB30527.1 - 9.5e-10 39.2 1.1 5.4e-09 36.8 0.0 2.8 2 0 0 2 2 2 1 HHH domain HHH_7 PF14635.6 VBB30527.1 - 1e-09 38.7 1.1 2.2e-09 37.6 0.1 2.2 2 0 0 2 2 1 1 Helix-hairpin-helix motif S1 PF00575.23 VBB30527.1 - 6.4e-06 26.4 0.2 1.5e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 VBB30527.1 - 2.8e-05 23.9 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_5 PF14520.6 VBB30527.1 - 0.0034 18.0 0.1 1.9 9.1 0.0 3.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 VBB30527.1 - 0.016 15.0 0.0 0.099 12.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HTH_44 PF14641.6 VBB30527.1 - 0.024 15.1 0.0 0.078 13.4 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 LMBR1 PF04791.16 VBB30527.1 - 0.19 10.6 0.2 0.36 9.7 0.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Prefoldin PF02996.17 VBB30527.1 - 8 6.4 6.7 0.43 10.5 0.7 1.9 2 0 0 2 2 2 0 Prefoldin subunit PAP_central PF04928.17 VBB30528.1 - 6.1e-104 346.4 0.0 1.1e-103 345.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 VBB30528.1 - 3.7e-26 91.8 0.2 9.3e-17 61.2 0.0 2.8 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 VBB30528.1 - 1.2e-09 38.3 0.0 2.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3715 PF12509.8 VBB30529.1 - 2.2e-06 27.7 0.0 5.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) XPG_I_2 PF12813.7 VBB30529.1 - 0.024 14.1 0.2 0.059 12.8 0.2 1.6 1 0 0 1 1 1 0 XPG domain containing BCOR PF15808.5 VBB30529.1 - 0.12 12.6 2.3 0.29 11.3 2.3 1.6 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region AAA_6 PF12774.7 VBB30530.1 - 6.3e-126 419.8 1.3 6.7e-125 416.4 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 VBB30530.1 - 2.9e-74 250.5 7.5 3.5e-71 240.4 2.7 5.3 4 1 1 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 VBB30530.1 - 3.6e-63 212.6 6.1 3.6e-63 212.6 6.1 4.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 VBB30530.1 - 4.8e-43 147.4 0.0 5.1e-42 144.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 VBB30530.1 - 6.6e-35 120.1 0.0 3.9e-22 78.8 0.0 7.1 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 VBB30530.1 - 9.3e-34 116.6 1.1 2.9e-33 115.0 0.2 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 VBB30530.1 - 1.5e-30 106.5 1.4 1.5e-30 106.5 1.4 3.1 5 0 0 5 5 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 VBB30530.1 - 5.9e-23 81.3 0.3 7.1e-18 64.8 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 VBB30530.1 - 1.3e-20 73.7 2.5 3.3e-10 40.1 0.0 4.8 3 1 1 4 4 3 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 VBB30530.1 - 4.8e-20 71.9 14.0 2.1e-18 66.4 14.0 2.5 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 VBB30530.1 - 2.6e-12 47.4 1.8 0.12 12.7 0.0 6.5 6 1 0 6 6 5 3 AAA ATPase domain AAA PF00004.29 VBB30530.1 - 1.7e-11 44.6 0.0 0.027 14.9 0.0 5.6 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB30530.1 - 9.9e-08 32.3 8.7 2.5 8.4 0.0 7.9 9 0 0 9 9 7 1 AAA domain AAA_18 PF13238.6 VBB30530.1 - 2.1e-06 28.3 0.0 0.029 14.9 0.0 4.6 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 VBB30530.1 - 2.6e-06 27.5 0.0 0.0097 15.8 0.1 3.0 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 VBB30530.1 - 3.2e-06 27.2 3.4 0.0015 18.5 0.0 5.0 5 0 0 5 5 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 VBB30530.1 - 3.3e-05 23.9 0.3 0.17 11.8 0.0 4.1 4 0 0 4 4 3 1 Rad17 P-loop domain AAA_24 PF13479.6 VBB30530.1 - 6.3e-05 22.8 0.2 0.11 12.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 VBB30530.1 - 0.00011 22.5 0.0 0.36 11.2 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 VBB30530.1 - 0.0002 21.2 0.0 0.64 9.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 VBB30530.1 - 0.00032 21.2 7.9 0.012 16.1 0.0 5.4 7 0 0 7 7 3 1 ABC transporter AAA_28 PF13521.6 VBB30530.1 - 0.00033 20.9 0.0 2.9 8.1 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_lid_7 PF17867.1 VBB30530.1 - 0.00053 20.2 0.1 0.0018 18.5 0.1 2.0 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_29 PF13555.6 VBB30530.1 - 0.0055 16.4 0.0 0.073 12.8 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 VBB30530.1 - 0.0062 16.7 0.5 0.0062 16.7 0.5 3.0 3 0 0 3 3 2 1 AAA+ lid domain ATP_bind_1 PF03029.17 VBB30530.1 - 0.012 15.4 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 VBB30530.1 - 0.016 14.1 0.3 0.23 10.2 0.0 2.7 3 0 0 3 3 3 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 VBB30530.1 - 0.046 13.4 0.4 4 7.1 0.0 3.7 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 VBB30530.1 - 0.069 13.3 0.0 2.3 8.4 0.0 3.5 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 VBB30530.1 - 0.072 12.5 0.1 1.5 8.2 0.0 3.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI GvpK PF05121.12 VBB30530.1 - 0.36 10.9 2.3 10 6.2 1.2 3.3 2 0 0 2 2 2 0 Gas vesicle protein K KxDL PF10241.9 VBB30530.1 - 4.8 7.5 13.0 0.17 12.1 2.0 4.3 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF2968 PF11180.8 VBB30530.1 - 4.8 6.8 10.5 5.4 6.6 3.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF948 PF06103.11 VBB30530.1 - 7.7 6.9 19.1 5.1 7.4 0.3 6.4 7 0 0 7 7 5 0 Bacterial protein of unknown function (DUF948) AAA_17 PF13207.6 VBB30530.1 - 8.3 6.8 6.2 83 3.6 0.1 4.3 4 0 0 4 4 3 0 AAA domain Pkinase PF00069.25 VBB30531.1 - 4e-18 65.7 0.0 4.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30531.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 VBB30531.1 - 0.0017 18.1 0.1 1.2 8.7 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 VBB30531.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 VBB30531.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF89 PF01937.19 VBB30532.1 - 3.5e-97 325.5 0.1 4e-97 325.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 TMEM51 PF15345.6 VBB30533.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 VBB30533.1 - 0.19 12.7 0.0 0.32 11.9 0.0 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase_Tyr PF07714.17 VBB30534.1 - 6.2e-73 245.3 0.0 2.5e-71 240.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30534.1 - 2.9e-30 105.5 0.0 1.4e-28 100.0 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Haspin_kinase PF12330.8 VBB30534.1 - 0.046 12.6 0.1 0.13 11.2 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain DUF4181 PF13789.6 VBB30534.1 - 0.32 11.3 1.4 22 5.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Dynein_AAA_lid PF17852.1 VBB30535.1 - 0.087 12.9 0.8 0.087 12.9 0.8 1.7 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain 2-oxoacid_dh PF00198.23 VBB30535.1 - 0.1 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Chromo PF00385.24 VBB30535.1 - 5.2 7.0 8.7 0.33 10.9 2.8 2.2 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Sec15 PF04091.12 VBB30536.1 - 1e-79 268.2 0.0 2.7e-79 266.8 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 VBB30536.1 - 0.0012 18.9 0.8 0.25 11.4 0.4 2.9 2 0 0 2 2 2 1 Vps51/Vps67 Lustrin_cystein PF14625.6 VBB30536.1 - 0.0013 19.1 1.7 0.0056 17.0 0.8 2.4 2 0 0 2 2 2 1 Lustrin, cysteine-rich repeated domain Zw10 PF06248.13 VBB30536.1 - 0.0028 16.3 6.8 0.0028 16.3 6.8 1.8 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 COG2 PF06148.11 VBB30536.1 - 0.082 13.0 1.6 0.67 10.0 1.1 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4119 PF13494.6 VBB30536.1 - 0.16 12.1 1.5 0.72 10.0 1.5 2.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Sec8_exocyst PF04048.14 VBB30536.1 - 0.31 10.9 5.3 0.073 13.0 0.7 2.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Mito_carr PF00153.27 VBB30537.1 - 5.9e-57 189.6 0.5 2.1e-17 62.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 VBB30537.1 - 0.096 11.8 0.1 0.81 8.8 0.0 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF3621 PF12285.8 VBB30538.1 - 0.06 13.7 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Zn_peptidase_2 PF04298.12 VBB30538.1 - 0.099 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase HEAT PF02985.22 VBB30540.1 - 1.4e-07 31.1 36.5 0.1 12.9 0.0 11.0 13 0 0 13 13 13 5 HEAT repeat HEAT_EZ PF13513.6 VBB30540.1 - 4.7e-07 30.2 15.3 0.028 14.9 0.3 8.9 9 1 1 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 VBB30540.1 - 2e-05 24.7 16.2 0.12 12.4 3.0 6.2 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 VBB30540.1 - 0.00068 20.0 14.0 0.32 11.4 1.6 7.8 9 1 2 11 11 11 2 HEAT repeats DUF3535 PF12054.8 VBB30540.1 - 0.0075 15.6 1.0 2.6 7.2 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3535) DUF3385 PF11865.8 VBB30540.1 - 0.0076 16.2 0.9 0.1 12.5 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FANCI_S2 PF14676.6 VBB30540.1 - 0.023 15.0 6.4 1.2 9.4 0.1 4.6 4 0 0 4 4 4 0 FANCI solenoid 2 CLASP_N PF12348.8 VBB30540.1 - 0.14 11.7 7.2 6.2 6.3 0.6 5.1 5 0 0 5 5 5 0 CLASP N terminal ICAT PF06384.11 VBB30541.1 - 1.7e-07 31.4 0.4 3.6e-07 30.3 0.1 1.8 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT FlxA PF14282.6 VBB30541.1 - 0.053 13.5 3.0 0.11 12.5 2.0 1.8 1 1 1 2 2 2 0 FlxA-like protein SOGA PF11365.8 VBB30541.1 - 0.62 11.2 6.7 3.7 8.7 0.4 2.6 2 1 0 2 2 2 0 Protein SOGA DUF1104 PF06518.11 VBB30541.1 - 0.92 9.9 5.3 3.6 8.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) BTB PF00651.31 VBB30542.1 - 3.3e-28 98.1 2.7 1.7e-26 92.7 0.8 2.3 1 1 1 2 2 2 2 BTB/POZ domain TERB2 PF15101.6 VBB30542.1 - 0.05 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TDP43_N PF18694.1 VBB30543.1 - 1.1e-20 73.2 0.0 2.2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 VBB30543.1 - 1e-19 70.1 0.3 5e-16 58.3 0.2 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB30543.1 - 0.035 14.2 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif RRM_7 PF16367.5 VBB30543.1 - 0.12 12.5 0.1 14 5.9 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif NICE-3 PF07406.11 VBB30544.1 - 3.7e-30 105.3 0.3 1.6e-29 103.2 0.1 2.0 2 1 0 2 2 2 1 NICE-3 protein AnfG_VnfG PF03139.15 VBB30544.1 - 0.05 13.7 0.7 0.96 9.6 0.0 2.4 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Bestrophin PF01062.21 VBB30545.1 - 1.6e-69 234.5 3.1 1.9e-69 234.3 3.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GlnD_UR_UTase PF08335.11 VBB30545.1 - 0.013 15.6 0.1 0.026 14.6 0.0 1.4 1 1 0 1 1 1 0 GlnD PII-uridylyltransferase Ras PF00071.22 VBB30546.1 - 4.9e-25 88.0 0.0 6.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB30546.1 - 7.5e-10 39.1 0.1 1.5e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 VBB30546.1 - 7.2e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 VBB30546.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family IBN_N PF03810.19 VBB30547.1 - 3.1e-08 33.4 0.4 6.2e-08 32.5 0.2 1.6 1 1 1 2 2 2 1 Importin-beta N-terminal domain zf-C3HC4 PF00097.25 VBB30550.1 - 1.7e-05 24.5 29.5 0.00045 20.0 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB30550.1 - 5.4e-05 23.1 20.4 0.00046 20.2 10.0 3.0 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 VBB30550.1 - 8.2e-05 22.9 33.1 0.0011 19.2 19.1 3.5 3 1 1 4 4 4 2 Ring finger domain zf-RING_11 PF17123.5 VBB30550.1 - 0.0009 18.9 5.1 0.0009 18.9 5.1 3.5 2 1 1 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 VBB30550.1 - 0.005 16.8 32.9 0.25 11.3 20.5 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB30550.1 - 0.0062 16.4 28.5 0.13 12.2 1.0 3.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB30550.1 - 0.19 11.6 29.8 1 9.3 2.3 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 VBB30550.1 - 8.8 6.6 25.6 0.34 11.1 1.8 3.5 2 2 0 2 2 2 0 zinc finger of C3HC4-type, RING Pkinase_Tyr PF07714.17 VBB30551.1 - 5.1e-87 291.4 0.0 6.5e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30551.1 - 2.7e-47 161.3 0.0 3.7e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 VBB30551.1 - 4.4e-08 33.1 0.0 9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Sec66 PF09802.9 VBB30551.1 - 0.045 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 SMK-1 PF04802.15 VBB30551.1 - 0.053 13.4 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 Kinase-like PF14531.6 VBB30551.1 - 0.059 12.7 0.0 0.6 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like EMP24_GP25L PF01105.24 VBB30552.1 - 2.2e-45 154.9 0.0 4.2e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 7tm_1 PF00001.21 VBB30552.1 - 3.5e-22 79.0 19.0 7.1e-22 78.0 19.0 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) P4Ha_N PF08336.11 VBB30553.1 - 1.6e-24 86.4 0.4 5.8e-24 84.6 0.4 2.0 1 1 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 VBB30553.1 - 2.2e-16 60.5 0.0 4.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 VBB30553.1 - 1.7e-08 34.8 0.0 3.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 VBB30553.1 - 2.6e-05 24.0 3.1 0.00025 20.9 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB30553.1 - 0.0039 17.2 0.1 0.0086 16.1 0.1 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 VBB30553.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 VBB30553.1 - 0.02 15.5 0.6 0.1 13.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB30553.1 - 0.071 13.3 0.3 0.48 10.7 0.1 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 VBB30553.1 - 0.087 13.3 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Patched PF02460.18 VBB30554.1 - 1.7e-177 592.0 7.1 2.3e-177 591.6 7.1 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB30554.1 - 6.7e-39 133.2 9.9 2.6e-37 128.0 2.0 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 VBB30554.1 - 1.9e-10 40.2 5.1 3.6e-08 32.7 0.2 2.3 2 0 0 2 2 2 2 MMPL family DUF1118 PF06549.12 VBB30554.1 - 0.0059 16.9 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1118) ACR_tran PF00873.19 VBB30554.1 - 0.41 8.2 8.7 0.066 10.9 1.6 2.1 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 VBB30554.1 - 8 5.8 12.2 1.4 8.2 2.2 2.5 2 0 0 2 2 2 0 Protein export membrane protein Ion_trans_2 PF07885.16 VBB30555.1 - 1.2e-09 38.0 5.9 2.1e-09 37.2 5.9 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 VBB30555.1 - 0.00019 20.7 2.8 0.00031 20.1 2.8 1.3 1 0 0 1 1 1 1 Ion transport protein TraB PF01963.17 VBB30555.1 - 0.041 13.8 2.2 0.062 13.2 2.2 1.2 1 0 0 1 1 1 0 TraB family Acyl_transf_3 PF01757.22 VBB30556.1 - 0.083 11.9 32.4 0.12 11.4 32.4 1.2 1 0 0 1 1 1 0 Acyltransferase family Metallophos PF00149.28 VBB30557.1 - 7.2e-34 118.1 1.5 3.4e-33 115.9 1.2 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 VBB30557.1 - 4.2e-32 110.3 1.0 9.3e-32 109.2 1.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 VBB30557.1 - 2e-09 36.9 8.6 4.4e-05 23.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB30557.1 - 3.6e-09 36.0 11.6 0.0017 18.3 0.1 4.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30557.1 - 2.7e-05 24.3 2.1 0.13 12.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30557.1 - 3.4e-05 23.4 6.2 0.0098 15.6 0.8 3.3 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 VBB30557.1 - 0.00038 20.4 11.0 1.1 9.7 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB30557.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB30557.1 - 0.0019 18.7 3.7 0.071 13.6 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30557.1 - 0.0019 18.8 2.6 0.14 12.8 0.4 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30557.1 - 0.0053 17.5 0.4 1.1 10.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB30557.1 - 0.033 14.5 2.7 2.6 8.4 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 VBB30557.1 - 0.13 12.7 0.2 0.23 11.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 VBB30557.1 - 0.96 10.2 2.6 1.7 9.4 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SPATA24 PF15175.6 VBB30558.1 - 0.0031 17.4 24.1 0.011 15.7 13.3 2.7 3 0 0 3 3 3 2 Spermatogenesis-associated protein 24 Speriolin_N PF15058.6 VBB30558.1 - 0.015 15.4 1.9 0.024 14.7 1.9 1.4 1 0 0 1 1 1 0 Speriolin N terminus CTK3 PF12243.8 VBB30558.1 - 0.015 15.3 1.1 0.031 14.3 0.7 1.8 1 1 0 1 1 1 0 CTD kinase subunit gamma CTK3 MutS_V PF00488.21 VBB30558.1 - 0.1 12.6 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 MutS domain V HALZ PF02183.18 VBB30558.1 - 0.41 10.9 0.1 0.41 10.9 0.1 5.8 6 1 0 6 6 6 0 Homeobox associated leucine zipper DUF3782 PF12644.7 VBB30558.1 - 2.7 8.2 7.4 3.6 7.8 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) CHDCT2 PF08074.11 VBB30558.1 - 3.1 8.0 10.4 0.84 9.8 6.8 1.9 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain SlyX PF04102.12 VBB30558.1 - 3.5 8.3 24.9 0.55 10.9 0.7 5.4 2 1 4 6 6 6 0 SlyX MFS_1 PF07690.16 VBB30562.1 - 5.6e-37 127.5 32.9 1.3e-35 122.9 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LrgA PF03788.14 VBB30562.1 - 0.28 11.2 6.2 1.1 9.3 1.4 3.5 2 1 1 3 3 3 0 LrgA family zf-C3HC4 PF00097.25 VBB30563.1 - 8.6e-06 25.5 4.1 2.3e-05 24.2 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 VBB30563.1 - 1.1e-05 25.0 5.2 3.3e-05 23.5 5.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 VBB30563.1 - 0.00028 21.1 8.4 0.00028 21.1 8.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB30563.1 - 0.00079 19.2 8.0 0.00079 19.2 8.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB30563.1 - 0.0013 18.7 1.8 0.0013 18.7 1.8 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 VBB30563.1 - 0.03 14.6 8.7 0.15 12.4 8.7 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 VBB30563.1 - 0.1 12.3 6.4 0.21 11.2 6.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 VBB30563.1 - 0.43 10.6 7.6 0.94 9.5 7.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 VBB30563.1 - 0.55 10.3 6.1 2.6 8.1 6.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Speriolin_N PF15058.6 VBB30563.1 - 0.94 9.5 2.6 1.4 8.9 2.6 1.2 1 0 0 1 1 1 0 Speriolin N terminus zf-RING_6 PF14835.6 VBB30563.1 - 2.2 8.2 7.7 2.6 8.0 6.1 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Ribosomal_S6e PF01092.19 VBB30565.1 - 1.1e-62 209.6 0.1 2.1e-62 208.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Helicase_C PF00271.31 VBB30566.1 - 2.6e-19 69.6 0.7 9.1e-19 67.9 0.7 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RIG-I_C-RD PF11648.8 VBB30566.1 - 6.2e-15 55.4 1.3 1.7e-14 54.1 1.3 1.7 1 0 0 1 1 1 1 C-terminal domain of RIG-I DEAD PF00270.29 VBB30566.1 - 1e-12 48.2 0.6 3.8e-09 36.5 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 VBB30566.1 - 3.4e-09 36.9 0.1 7e-08 32.7 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C PF18119.1 VBB30566.1 - 6.3e-09 36.0 0.0 6.3e-09 36.0 0.0 3.6 4 1 0 4 4 4 1 RIG-I receptor C-terminal domain AAA_22 PF13401.6 VBB30566.1 - 0.0023 18.2 0.2 0.17 12.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 VBB30566.1 - 0.057 13.8 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain MAPKK1_Int PF08923.10 VBB30567.1 - 7.6e-16 58.0 0.2 8.8e-16 57.8 0.2 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.17 VBB30567.1 - 0.0063 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Roadblock/LC7 domain Pellino PF04710.14 VBB30568.1 - 5e-174 578.8 0.1 6.8e-174 578.4 0.1 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 VBB30568.1 - 0.0029 17.4 3.6 0.92 9.4 0.1 3.3 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 VBB30568.1 - 0.035 14.4 1.5 2.9 8.2 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 VBB30568.1 - 0.041 13.9 2.1 4.3 7.5 0.1 3.3 1 1 2 3 3 3 0 RING-type zinc-finger Herpes_TK PF00693.18 VBB30568.1 - 0.082 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus zf-RING_2 PF13639.6 VBB30568.1 - 0.32 11.4 4.6 6.8 7.1 0.2 3.1 3 1 0 3 3 3 0 Ring finger domain Beta-lactamase PF00144.24 VBB30569.1 - 3.6e-10 39.6 0.0 4e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Roc PF08477.13 VBB30570.1 - 3.6e-13 49.8 0.1 1.6e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB30570.1 - 1.7e-10 40.8 0.0 1.3e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Ras family DnaJ PF00226.31 VBB30570.1 - 1.8e-10 40.8 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain MMR_HSR1 PF01926.23 VBB30570.1 - 4.7e-07 29.9 0.0 9.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-CSL PF05207.13 VBB30570.1 - 0.00022 20.9 1.9 0.00064 19.4 1.9 1.8 1 0 0 1 1 1 1 CSL zinc finger RsgA_GTPase PF03193.16 VBB30570.1 - 0.00045 20.2 0.0 0.0017 18.3 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 VBB30570.1 - 0.00075 19.6 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 VBB30570.1 - 0.0024 18.3 0.0 0.005 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 VBB30570.1 - 0.0044 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RNA_helicase PF00910.22 VBB30570.1 - 0.008 16.6 0.0 0.078 13.4 0.0 2.2 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 VBB30570.1 - 0.021 14.0 0.0 0.048 12.8 0.0 1.7 1 1 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 VBB30570.1 - 0.037 13.3 0.2 0.066 12.5 0.0 1.5 2 0 0 2 2 2 0 Septin Arf PF00025.21 VBB30570.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Hpr_kinase_C PF07475.12 VBB30570.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 VBB30570.1 - 0.15 11.8 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sgf11 PF08209.11 VBB30570.1 - 0.22 11.1 2.3 0.67 9.6 0.5 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Tmemb_185A PF10269.9 VBB30571.1 - 2.5e-55 187.9 21.4 3.6e-55 187.4 21.4 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF4059 PF13268.6 VBB30571.1 - 0.0022 18.3 2.8 0.0022 18.3 2.8 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4059) MHYT PF03707.16 VBB30571.1 - 0.86 9.8 9.8 2 8.7 1.3 3.6 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat HSNSD PF12062.8 VBB30572.1 - 5.5e-190 632.3 1.4 9e-190 631.6 1.4 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 VBB30572.1 - 8.9e-27 94.2 0.0 1.7e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 VBB30572.1 - 9.1e-09 36.0 0.6 0.00089 19.7 0.2 2.5 1 1 1 2 2 2 2 Sulfotransferase family WAPL PF07814.13 VBB30573.1 - 3.2e-75 253.2 16.3 4.7e-75 252.7 16.3 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin adh_short PF00106.25 VBB30573.1 - 1.4e-43 148.7 0.4 2.6e-43 147.7 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB30573.1 - 8.5e-42 143.3 0.1 1.3e-41 142.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB30573.1 - 5.9e-09 36.1 1.0 1.3e-08 35.0 1.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 VBB30573.1 - 0.00025 20.6 0.5 0.0017 17.8 0.5 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2543 PF10820.8 VBB30573.1 - 0.24 11.6 1.0 0.8 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) adh_short_C2 PF13561.6 VBB30574.1 - 3.1e-12 46.6 0.0 3.9e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 VBB30574.1 - 3.5e-11 42.9 0.0 4.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Sec6 PF06046.13 VBB30575.1 - 1.6e-20 73.0 1.3 2e-20 72.7 1.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 ACP_PD PF04336.12 VBB30575.1 - 0.046 14.2 0.5 3.4 8.1 0.0 2.8 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase MHCassoc_trimer PF08831.10 VBB30575.1 - 0.16 12.0 0.3 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Transket_pyr PF02779.24 VBB30576.1 - 5.2e-45 153.3 0.0 7.6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 VBB30576.1 - 2.3e-38 130.8 0.0 4.4e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 VBB30576.1 - 0.00022 21.5 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II bMG1 PF17970.1 VBB30576.1 - 0.0036 17.3 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG1 domain DUF900 PF05990.12 VBB30576.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GntR PF00392.21 VBB30576.1 - 0.15 11.7 0.1 0.36 10.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family LIDHydrolase PF10230.9 VBB30576.1 - 0.18 11.3 0.1 0.78 9.2 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DEAD PF00270.29 VBB30577.1 - 3.5e-44 150.7 0.0 1.1e-43 149.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB30577.1 - 6.7e-29 100.5 2.9 2e-28 99.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB30577.1 - 5.3e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Piwi PF02171.17 VBB30578.1 - 2.2e-54 184.8 2.0 4.8e-54 183.7 1.8 1.7 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 VBB30578.1 - 2.6e-07 31.3 0.3 4.2e-06 27.4 0.1 2.8 2 1 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 VBB30578.1 - 0.0011 19.2 0.0 0.0091 16.3 0.0 2.6 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 VBB30578.1 - 0.0019 18.4 1.0 0.031 14.5 0.1 3.5 4 0 0 4 4 4 1 Mid domain of argonaute SAM_1 PF00536.30 VBB30579.1 - 4.2e-30 104.0 2.9 3.3e-14 53.1 0.5 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB30579.1 - 5.4e-30 103.3 4.2 9e-13 48.1 0.1 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 VBB30579.1 - 0.0093 15.9 1.7 0.22 11.5 0.0 3.0 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain HAP1_N PF04849.13 VBB30579.1 - 0.37 9.9 14.4 0.038 13.2 9.5 1.8 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Troponin PF00992.20 VBB30579.1 - 0.57 10.5 10.8 0.24 11.7 7.1 2.2 2 1 0 2 2 2 0 Troponin DUF573 PF04504.14 VBB30579.1 - 0.6 10.8 2.6 1.1 9.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 UPF0242 PF06785.11 VBB30579.1 - 0.85 9.7 14.2 2.3 8.3 13.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 VBB30579.1 - 3.1 7.9 23.2 0.14 12.1 6.0 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 VBB30579.1 - 7.3 6.6 22.8 1.1 9.3 7.6 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1645 PF07816.11 VBB30580.1 - 0.12 12.9 8.7 0.14 12.8 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Apt1 PF10351.9 VBB30580.1 - 2.1 7.1 10.1 2.4 6.9 10.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L18 PF17135.4 VBB30582.1 - 2.5e-90 300.9 2.7 2.8e-90 300.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 VBB30582.1 - 0.012 16.2 0.4 0.029 15.0 0.4 1.7 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 VBB30583.1 - 1.7e-07 30.9 0.0 3.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 VBB30583.1 - 1.5e-06 28.7 2.1 1.5e-06 28.7 2.1 2.8 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 NKAP PF15692.5 VBB30583.1 - 0.033 14.9 0.3 0.033 14.9 0.3 2.5 2 1 0 2 2 2 0 NF-kappa-B-activating protein Rota_VP4_MID PF17477.2 VBB30584.1 - 0.043 13.2 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Rotavirus VP4 membrane interaction domain MetW PF07021.12 VBB30584.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW SNF2_N PF00176.23 VBB30586.1 - 6e-60 202.8 0.0 1.6e-59 201.4 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain RCC1 PF00415.18 VBB30586.1 - 1.2e-19 70.7 2.6 6e-12 46.0 0.4 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB30586.1 - 3.9e-15 55.2 6.7 4.3e-09 35.9 4.0 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat zf-C3HC4_3 PF13920.6 VBB30586.1 - 1.7e-05 24.6 6.9 1.7e-05 24.6 6.9 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 VBB30586.1 - 4.9e-05 23.6 0.1 0.00015 22.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 VBB30586.1 - 0.00033 20.9 8.1 0.00033 20.9 8.1 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 VBB30586.1 - 0.0005 20.0 4.9 0.0005 20.0 4.9 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB30586.1 - 0.0029 17.4 6.5 0.0029 17.4 6.5 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB30586.1 - 0.003 17.4 6.2 0.003 17.4 6.2 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB30586.1 - 0.0078 16.0 4.7 0.0078 16.0 4.7 2.9 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 VBB30586.1 - 0.14 12.2 8.1 0.088 12.8 4.2 2.8 2 0 0 2 2 2 0 RING-type zinc-finger NUDIX PF00293.28 VBB30587.1 - 1.2e-09 38.3 0.0 2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.22 VBB30588.1 - 2.1e-21 75.5 0.0 2.9e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 VBB30588.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 VBB30588.1 - 0.093 12.8 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Limkain b1 LAMTOR PF15454.6 VBB30591.1 - 0.00056 20.5 0.1 0.001 19.6 0.1 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator COPI_C PF06957.11 VBB30593.1 - 1.4e-169 564.1 0.0 1.9e-169 563.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 VBB30593.1 - 4.6e-133 444.5 0.9 7.3e-133 443.9 0.9 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 VBB30593.1 - 3.9e-39 131.9 21.3 7.3e-07 29.8 0.1 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30593.1 - 8.4e-11 42.0 0.9 2.2e-06 27.9 0.1 5.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 VBB30593.1 - 0.012 14.9 0.1 0.029 13.6 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 TPR_14 PF13428.6 VBB30593.1 - 0.036 14.9 0.9 68 4.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1110 PF06533.12 VBB30593.1 - 0.048 13.6 0.1 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) Nup160 PF11715.8 VBB30593.1 - 0.086 11.5 3.2 2.2 6.8 0.0 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Chromadorea_ALT PF05535.12 VBB30594.1 - 5.7e-25 87.3 8.2 5.7e-25 87.3 8.2 1.4 2 0 0 2 2 2 1 Chromadorea ALT protein Chromadorea_ALT PF05535.12 VBB30595.1 - 1.4e-29 102.1 7.5 1.9e-29 101.7 7.5 1.2 1 0 0 1 1 1 1 Chromadorea ALT protein NSP11 PF06471.12 VBB30595.1 - 0.022 13.3 0.2 0.022 13.2 0.2 1.1 1 0 0 1 1 1 0 NSP11 Sulfotransfer_2 PF03567.14 VBB30596.1 - 1.9e-52 178.7 0.2 2.4e-52 178.4 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family VMA21 PF09446.10 VBB30596.1 - 0.37 10.9 2.3 0.37 10.9 0.5 1.9 2 0 0 2 2 2 0 VMA21-like domain HMG_box PF00505.19 VBB30597.1 - 4.3e-17 62.3 3.4 6e-17 61.8 3.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB30597.1 - 9.5e-12 45.4 4.1 1.4e-11 44.8 4.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 VBB30597.1 - 0.001 19.0 7.3 0.0013 18.6 6.4 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box 5 PPI_Ypi1 PF07491.11 VBB30598.1 - 0.02 14.7 0.0 0.076 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor DUF2992 PF11208.8 VBB30598.1 - 0.079 13.2 1.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Myotub-related PF06602.14 VBB30599.1 - 5.4e-74 249.2 0.1 7.8e-73 245.4 0.0 2.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain SBF2 PF12335.8 VBB30599.1 - 5.7e-69 232.2 2.9 9.5e-69 231.5 2.9 1.3 1 0 0 1 1 1 1 Myotubularin protein DENN PF02141.21 VBB30599.1 - 3.3e-35 121.7 2.5 8.1e-35 120.5 2.5 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain PH PF00169.29 VBB30599.1 - 4.8e-13 49.5 0.0 1.3e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 VBB30599.1 - 9.6e-13 48.0 0.1 2.4e-10 40.3 0.1 3.5 2 1 0 2 2 2 1 GRAM domain uDENN PF03456.18 VBB30599.1 - 8.4e-11 42.5 0.0 2.1e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.22 VBB30599.1 - 7.5e-06 25.7 7.7 1.6e-05 24.7 7.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_8 PF15409.6 VBB30599.1 - 1e-05 25.7 0.1 2.6e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 VBB30599.1 - 2.3e-05 24.8 0.1 8.2e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain dDENN PF03455.19 VBB30599.1 - 4.7e-05 23.3 2.1 0.0002 21.3 2.1 2.2 1 0 0 1 1 1 1 dDENN domain DUF5615 PF18480.1 VBB30599.1 - 0.12 12.2 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) GDNF PF02351.16 VBB30600.1 - 0.97 10.4 4.4 2.9 8.9 4.4 1.9 1 1 0 1 1 1 0 GDNF/GAS1 domain TMEMspv1-c74-12 PF11044.8 VBB30601.1 - 0.028 14.4 3.4 0.039 13.9 0.9 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF1218 PF06749.12 VBB30601.1 - 0.088 13.3 8.0 0.09 13.3 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4337 PF14235.6 VBB30601.1 - 0.16 12.0 3.0 1.1 9.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Ninjurin PF04923.12 VBB30601.1 - 2.7 8.0 8.0 0.21 11.6 1.4 2.4 2 1 0 2 2 2 0 Ninjurin Ion_trans PF00520.31 VBB30602.1 - 5.5e-86 287.8 73.2 4.2e-29 101.5 26.9 3.2 3 0 0 3 3 3 3 Ion transport protein PsaF PF17550.2 VBB30602.1 - 0.059 12.9 0.9 0.17 11.4 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function KH_1 PF00013.29 VBB30603.1 - 2.3e-45 152.3 17.4 8e-12 44.8 1.1 6.7 6 1 0 6 6 6 6 KH domain KH_2 PF07650.17 VBB30603.1 - 6.5e-11 41.9 11.1 0.0023 17.7 0.0 4.7 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 VBB30603.1 - 1.4e-07 31.3 3.8 0.015 15.2 0.3 4.4 4 0 0 4 4 4 2 KH domain KH_5 PF13184.6 VBB30603.1 - 2.1e-06 27.7 6.1 0.52 10.4 0.1 4.6 4 0 0 4 4 4 3 NusA-like KH domain Zip PF02535.22 VBB30603.1 - 0.17 11.1 7.6 0.021 14.1 0.8 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Exog_C PF18026.1 VBB30604.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Sarcoglycan_2 PF05510.13 VBB30605.1 - 8.9e-25 87.3 0.1 1.2e-24 86.8 0.1 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Cyc-maltodext_C PF10438.9 VBB30605.1 - 0.16 12.1 0.5 0.36 10.9 0.5 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain RRM_1 PF00076.22 VBB30606.1 - 3.7e-13 49.1 0.0 4.4e-08 32.8 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB30606.1 - 0.018 15.1 0.1 0.41 10.8 0.0 2.9 3 1 1 4 4 4 0 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB30606.1 - 0.081 12.9 0.1 2.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PUF PF00806.19 VBB30607.1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat ACPS PF01648.20 VBB30608.1 - 3.8e-14 52.8 0.0 6.9e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Biopterin_H PF00351.21 VBB30608.1 - 0.12 11.4 0.0 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 Biopterin-dependent aromatic amino acid hydroxylase NOA36 PF06524.12 VBB30609.1 - 0.078 12.3 15.1 0.12 11.7 15.1 1.3 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 VBB30609.1 - 3.8 7.6 9.5 5.7 7.0 9.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein P34-Arc PF04045.14 VBB30610.1 - 4e-98 327.9 0.1 4.9e-98 327.6 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Phage_int_SAM_5 PF13102.6 VBB30610.1 - 0.055 13.8 0.3 0.18 12.2 0.3 1.8 1 0 0 1 1 1 0 Phage integrase SAM-like domain SNF PF00209.18 VBB30611.1 - 2.2e-150 501.8 44.5 4.4e-150 500.8 44.5 1.4 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Stealth_CR3 PF17102.5 VBB30611.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 DUF3020 PF11223.8 VBB30612.1 - 0.0051 17.3 0.3 0.0073 16.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3020) EGF_CA PF07645.15 VBB30613.1 - 1.4e-106 348.5 394.1 1.5e-07 31.5 3.8 32.4 32 0 0 32 32 32 27 Calcium-binding EGF domain EGF_3 PF12947.7 VBB30613.1 - 6.7e-86 282.2 392.2 3.8e-07 30.2 4.4 32.6 32 1 1 33 33 33 27 EGF domain EGF PF00008.27 VBB30613.1 - 9e-77 252.9 365.2 3.6e-06 27.2 3.5 32.7 33 0 0 33 33 33 28 EGF-like domain hEGF PF12661.7 VBB30613.1 - 5.5e-68 223.5 300.7 8.7e-06 26.2 3.3 34.1 33 0 0 33 33 33 26 Human growth factor-like EGF FXa_inhibition PF14670.6 VBB30613.1 - 3.9e-20 71.8 383.3 0.0011 19.1 4.8 32.8 33 0 0 33 33 33 27 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 VBB30613.1 - 1.1e-10 41.6 334.2 0.00062 20.0 7.2 32.1 32 0 0 32 32 32 20 Pvs28 EGF domain cEGF PF12662.7 VBB30613.1 - 5.3e-05 23.1 244.4 0.023 14.6 1.0 30.8 31 1 0 31 31 31 16 Complement Clr-like EGF-like SEA PF01390.20 VBB30613.1 - 0.0013 18.8 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 SEA domain DUF2884 PF11101.8 VBB30614.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF4885 PF16226.5 VBB30614.1 - 0.036 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) PilP PF04351.13 VBB30614.1 - 0.041 13.8 0.3 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Pilus assembly protein, PilP zf-C3HC4_2 PF13923.6 VBB30615.1 - 7.3e-12 44.9 13.6 1.5e-11 43.9 13.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB30615.1 - 1.2e-09 37.9 10.4 2.3e-09 37.0 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB30615.1 - 3.6e-07 30.4 12.2 7.1e-07 29.5 12.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 VBB30615.1 - 2.1e-06 27.7 9.4 4.5e-06 26.6 9.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 VBB30615.1 - 5.7e-06 26.1 10.3 9.3e-06 25.4 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB30615.1 - 0.0001 22.2 12.2 0.00022 21.1 12.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 VBB30615.1 - 0.00015 21.8 7.9 0.00029 20.9 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING BUD22 PF09073.10 VBB30615.1 - 0.00063 19.2 3.8 0.00095 18.6 3.8 1.2 1 0 0 1 1 1 1 BUD22 zf-Nse PF11789.8 VBB30615.1 - 0.0025 17.6 6.9 0.0051 16.6 6.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 VBB30615.1 - 0.0094 15.7 8.6 0.027 14.3 8.6 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 VBB30615.1 - 0.029 14.6 8.1 0.029 14.6 8.1 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 VBB30615.1 - 0.057 13.3 6.2 0.12 12.3 6.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 VBB30615.1 - 0.17 12.1 0.7 6.1 7.1 0.1 2.8 3 0 0 3 3 2 0 U-box domain zf-C3HC4_5 PF17121.5 VBB30615.1 - 0.35 10.8 7.1 0.98 9.4 7.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB30615.1 - 0.95 9.4 10.9 1.6 8.7 8.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 G_path_suppress PF15991.5 VBB30615.1 - 1.3 9.1 8.7 0.38 10.9 5.4 1.7 2 0 0 2 2 2 0 G-protein pathway suppressor RIBIOP_C PF04950.12 VBB30616.1 - 7.9e-90 301.2 0.5 7.9e-90 301.2 0.5 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 VBB30616.1 - 3.4e-28 97.6 1.4 2.1e-27 95.0 0.0 3.0 3 0 0 3 3 2 1 AARP2CN (NUC121) domain Ank_2 PF12796.7 VBB30616.1 - 4.1e-12 46.5 0.0 1.5e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 VBB30616.1 - 4e-09 36.5 0.0 6.8e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 VBB30616.1 - 2.3e-07 31.2 0.1 4.9e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB30616.1 - 8.1e-07 29.2 0.1 2.3e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30616.1 - 8.6e-07 28.8 0.0 0.0011 19.3 0.0 3.3 3 0 0 3 3 2 1 Ankyrin repeat MMR_HSR1 PF01926.23 VBB30616.1 - 5.2e-05 23.3 0.0 0.00027 21.0 0.0 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 VBB30616.1 - 0.00016 21.3 5.5 0.00055 19.5 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 VBB30616.1 - 0.0047 17.2 0.0 0.024 14.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB30616.1 - 0.0069 16.8 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 VBB30616.1 - 0.03 14.2 0.3 0.23 11.4 0.1 2.4 1 1 1 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 VBB30616.1 - 0.033 14.7 2.2 0.076 13.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 VBB30616.1 - 0.44 10.6 0.0 0.44 10.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain BAAT_C PF08840.11 VBB30616.1 - 0.94 9.4 5.3 3.1 7.7 5.3 1.9 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AAA_18 PF13238.6 VBB30616.1 - 3.7 8.1 6.7 1.6 9.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 VBB30618.1 - 5.1e-68 229.7 46.0 3.6e-30 105.6 17.5 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 VBB30618.1 - 4.2e-41 140.7 2.0 2.6e-26 92.7 0.0 3.9 4 0 0 4 4 4 3 ABC transporter SMC_N PF02463.19 VBB30618.1 - 1.2e-07 31.4 0.0 0.00032 20.2 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF632 PF04782.12 VBB30618.1 - 0.01 15.2 1.6 0.063 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF632) MMR_HSR1 PF01926.23 VBB30618.1 - 0.027 14.6 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 VBB30618.1 - 0.04 13.6 0.7 8 6.2 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.13 VBB30618.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 VBB30618.1 - 0.16 11.7 0.5 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 VBB30618.1 - 0.72 9.9 3.0 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Eapp_C PF10238.9 VBB30619.1 - 2.1e-40 138.2 3.7 2.1e-40 138.2 3.7 2.6 2 1 0 2 2 2 1 E2F-associated phosphoprotein Macoilin PF09726.9 VBB30619.1 - 1.8 7.0 20.2 2.6 6.5 20.2 1.2 1 0 0 1 1 1 0 Macoilin family SAM_4 PF18017.1 VBB30620.1 - 5.7e-15 55.1 0.1 2.6e-14 52.9 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 VBB30620.1 - 3e-05 23.9 1.8 6.2e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 Family of unknown function (DUF5577) SAM_1 PF00536.30 VBB30620.1 - 0.00016 22.0 0.2 0.00051 20.4 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB30620.1 - 0.028 14.5 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF573 PF04504.14 VBB30620.1 - 0.11 13.2 1.5 1.6 9.4 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function, DUF573 Moulting_cycle PF04870.16 VBB30621.1 - 1.5e-65 221.8 16.9 1.5e-65 221.8 16.9 3.4 3 1 0 3 3 3 1 Moulting cycle Vps23_core PF09454.10 VBB30621.1 - 0.093 12.7 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Vps23 core domain DB PF01682.19 VBB30622.1 - 5.7e-06 26.6 8.1 9.1e-06 25.9 8.1 1.3 1 0 0 1 1 1 1 DB module DUF273 PF03314.14 VBB30623.1 - 3.3e-61 206.6 0.5 6.5e-61 205.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 OLF PF02191.16 VBB30623.1 - 7e-59 199.4 9.0 9.7e-59 198.9 9.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 VBB30623.1 - 2.1e-08 33.8 21.5 3.7e-08 33.0 21.5 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Hexokinase_2 PF03727.16 VBB30624.1 - 4.2e-33 114.8 0.0 7.4e-33 114.0 0.0 1.4 1 1 0 1 1 1 1 Hexokinase CPG4 PF15481.6 VBB30626.1 - 1.9e-09 38.0 10.3 1.2e-07 32.2 1.3 3.3 2 1 1 3 3 3 2 Chondroitin proteoglycan 4 DUF4827 PF16109.5 VBB30626.1 - 0.0016 18.5 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4827) zf-RING_2 PF13639.6 VBB30627.1 - 5.9e-08 32.9 2.6 2.6e-07 30.8 2.6 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 VBB30627.1 - 8.7e-06 25.5 2.4 4.2e-05 23.3 2.4 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB30627.1 - 9.4e-06 25.8 2.1 3e-05 24.2 2.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB30627.1 - 1.2e-05 25.0 0.9 4e-05 23.4 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB30627.1 - 2e-05 24.5 0.6 6.8e-05 22.8 0.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB30627.1 - 0.00011 22.0 2.6 0.00036 20.3 2.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 VBB30627.1 - 0.00014 21.6 0.8 0.00057 19.6 0.8 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 VBB30627.1 - 0.00014 21.4 1.4 0.00043 19.8 1.4 1.9 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 VBB30627.1 - 0.00055 20.0 1.6 0.0019 18.3 1.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 VBB30627.1 - 0.0012 18.8 0.3 0.003 17.6 0.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 VBB30627.1 - 0.0013 18.6 2.1 0.0043 17.0 2.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 VBB30627.1 - 0.017 15.0 0.9 0.055 13.3 0.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_4 PF13717.6 VBB30627.1 - 0.04 13.8 2.0 5.4 7.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain YabA PF06156.13 VBB30627.1 - 0.053 14.1 7.0 0.33 11.6 1.7 2.9 1 1 1 2 2 2 0 Initiation control protein YabA KLRAQ PF10205.9 VBB30627.1 - 0.071 13.4 4.7 0.75 10.1 4.7 2.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein HypA PF01155.19 VBB30627.1 - 0.075 13.1 0.2 0.21 11.6 0.2 1.8 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 VBB30627.1 - 0.075 12.8 1.5 3.9 7.3 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 VBB30627.1 - 0.16 12.1 1.6 0.46 10.7 1.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_4 PF14570.6 VBB30627.1 - 0.42 10.5 3.9 1.5 8.7 3.9 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 VBB30627.1 - 0.79 9.9 3.3 0.5 10.5 0.7 2.0 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE PF01363.21 VBB30627.1 - 0.93 9.7 6.0 13 6.0 1.3 2.9 1 1 1 2 2 2 0 FYVE zinc finger Cep57_CLD_2 PF14197.6 VBB30627.1 - 3.1 7.9 7.7 7.2 6.8 7.7 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 VBB30627.1 - 5.5 7.5 11.4 5.4e+02 1.1 11.4 2.4 1 1 0 1 1 1 0 Cell division protein ZapB PikAIV_N PF18605.1 VBB30627.1 - 7.7 6.2 8.2 6.8 6.4 1.7 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ank_2 PF12796.7 VBB30628.1 - 1.1e-15 57.9 0.0 7.4e-06 26.5 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ion_trans PF00520.31 VBB30628.1 - 4.3e-13 49.1 20.3 6.2e-13 48.5 20.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 VBB30628.1 - 7.4e-13 48.3 2.2 0.0026 18.1 0.1 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 VBB30628.1 - 1.6e-11 44.5 0.1 0.0072 16.9 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30628.1 - 4.3e-11 42.0 1.8 0.005 17.2 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat PKD_channel PF08016.12 VBB30628.1 - 7.5e-07 28.2 4.8 7.5e-07 28.2 4.8 2.1 2 0 0 2 2 2 1 Polycystin cation channel Ank_5 PF13857.6 VBB30628.1 - 4.1e-06 27.0 1.5 0.062 13.6 0.0 4.4 3 2 1 4 4 4 2 Ankyrin repeats (many copies) TMEM18 PF14770.6 VBB30628.1 - 0.017 15.1 0.6 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Transmembrane protein 18 CUB PF00431.20 VBB30629.1 - 2.2e-15 57.0 0.1 4.5e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 CUB domain TMEM154 PF15102.6 VBB30629.1 - 1.8e-05 24.7 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Ldl_recept_a PF00057.18 VBB30629.1 - 0.0013 18.9 11.1 0.0087 16.3 6.3 2.6 1 1 1 2 2 2 1 Low-density lipoprotein receptor domain class A Phage_Gp23 PF10669.9 VBB30629.1 - 0.0016 18.8 0.1 0.0036 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) EphA2_TM PF14575.6 VBB30629.1 - 0.058 14.3 1.7 0.23 12.4 1.7 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM100 PF16311.5 VBB30629.1 - 0.076 12.6 1.3 0.086 12.4 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 100 Vpu PF00558.19 VBB30629.1 - 0.081 12.7 0.5 0.081 12.7 0.5 1.7 2 0 0 2 2 2 0 Vpu protein NicO PF03824.16 VBB30629.1 - 0.19 11.0 0.3 0.31 10.3 0.3 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein YajC PF02699.15 VBB30629.1 - 3.5 7.6 7.2 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Peptidase_M24 PF00557.24 VBB30630.1 - 5.1e-42 143.9 0.1 7.2e-42 143.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 VBB30630.1 - 2.9e-25 88.4 0.0 5.6e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HBS1_N PF08938.10 VBB30631.1 - 0.0025 18.1 0.8 0.0057 16.9 0.8 1.6 1 0 0 1 1 1 1 HBS1 N-terminus API5 PF05918.11 VBB30631.1 - 0.2 10.4 3.1 0.47 9.2 3.1 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MutS_V PF00488.21 VBB30632.1 - 5.4e-60 202.7 0.3 9.4e-60 201.9 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 VBB30632.1 - 2.3e-34 118.0 0.1 5e-34 116.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 VBB30632.1 - 4.8e-31 108.5 0.1 7.8e-30 104.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 VBB30632.1 - 9.7e-10 38.7 0.1 2.2e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 VBB30632.1 - 8.7e-09 35.8 0.3 4.2e-08 33.6 0.0 2.4 2 1 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 VBB30632.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2894 PF11445.8 VBB30632.1 - 0.19 12.2 1.1 0.4 11.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) RRM_1 PF00076.22 VBB30633.1 - 1.7e-22 79.0 0.1 7.3e-13 48.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB30633.1 - 5.1e-06 26.5 0.0 0.11 12.7 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif DUF787 PF05619.11 VBB30635.1 - 0.09 11.9 0.2 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Pkinase PF00069.25 VBB30636.1 - 4.3e-20 72.2 0.0 5.8e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30636.1 - 1.8e-12 47.1 0.0 2.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB30636.1 - 1.4e-07 30.7 0.3 4.1e-07 29.1 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 VBB30636.1 - 0.0041 17.1 0.1 17 5.2 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family WD40 PF00400.32 VBB30639.1 - 1.1e-12 48.2 7.6 4.6e-05 24.1 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30639.1 - 6.7e-11 42.3 0.0 0.0026 18.0 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 VBB30639.1 - 3.4e-08 33.2 1.9 0.41 10.6 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 VBB30639.1 - 7.5e-06 26.0 0.1 0.096 12.6 0.0 3.9 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 VBB30639.1 - 0.0029 17.3 0.4 1.9 8.2 0.0 3.5 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 VBB30639.1 - 0.0046 16.0 0.0 3.2 6.6 0.0 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 VBB30639.1 - 0.17 10.6 0.3 9.2 4.9 0.2 3.1 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region tRNA-synt_1b PF00579.25 VBB30640.1 - 2.8e-54 184.4 0.0 6.4e-52 176.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Nt_Gln_amidase PF09764.9 VBB30640.1 - 7e-38 130.1 0.5 1.3e-37 129.2 0.5 1.4 1 0 0 1 1 1 1 N-terminal glutamine amidase Exo_endo_phos PF03372.23 VBB30641.1 - 1.2e-06 28.2 0.0 2.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DcpS_C PF11969.8 VBB30642.1 - 1.2e-20 74.1 1.0 1.7e-20 73.6 1.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 VBB30642.1 - 2.2e-06 28.3 2.5 5.4e-06 27.1 2.5 1.7 1 1 0 1 1 1 1 HIT domain RRM_1 PF00076.22 VBB30643.1 - 8.8e-40 134.4 0.2 9.2e-16 57.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB30643.1 - 6.3e-05 23.0 0.0 0.3 11.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif HicB-like_2 PF15970.5 VBB30643.1 - 0.19 11.9 1.2 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 HicB_like antitoxin of bacterial toxin-antitoxin system OB_RNB PF08206.11 VBB30643.1 - 0.68 9.7 0.0 0.68 9.7 0.0 2.1 3 0 0 3 3 3 0 Ribonuclease B OB domain BAG PF02179.16 VBB30644.1 - 1.9e-06 28.2 0.9 3.1e-06 27.5 0.9 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 VBB30644.1 - 1e-05 25.2 0.0 2.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family RBD-FIP PF09457.10 VBB30644.1 - 0.055 13.4 0.6 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 FIP domain SKA2 PF16740.5 VBB30644.1 - 0.21 11.4 3.2 0.3 10.9 1.3 2.1 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 PHD PF00628.29 VBB30645.1 - 5.3e-07 29.4 8.6 1e-06 28.5 8.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 VBB30645.1 - 0.0017 18.2 3.2 0.0017 18.2 3.2 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 VBB30645.1 - 0.0026 17.3 0.6 0.0026 17.3 0.6 2.0 2 0 0 2 2 2 1 PHD-finger Amidinotransf PF02274.17 VBB30645.1 - 0.0039 16.3 0.2 0.0039 16.3 0.2 1.4 2 0 0 2 2 2 1 Amidinotransferase C1_2 PF03107.16 VBB30645.1 - 0.54 10.6 8.3 0.2 12.0 4.2 2.3 2 0 0 2 2 2 0 C1 domain MCM_OB PF17207.3 VBB30645.1 - 0.84 9.5 5.2 1.9 8.4 5.2 1.6 1 0 0 1 1 1 0 MCM OB domain FYVE_2 PF02318.16 VBB30645.1 - 1.1 9.4 12.4 0.051 13.8 5.0 2.3 2 1 0 2 2 2 0 FYVE-type zinc finger PHD_4 PF16866.5 VBB30645.1 - 3.7 7.7 11.9 20 5.4 10.3 2.9 1 1 1 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 VBB30645.1 - 4.5 7.7 8.5 8.5 6.8 8.5 1.5 1 0 0 1 1 1 0 Ring finger domain IDO PF01231.18 VBB30646.1 - 6.7e-82 275.6 0.0 2.1e-81 274.0 0.0 1.6 1 1 1 2 2 2 1 Indoleamine 2,3-dioxygenase PAD_porph PF04371.15 VBB30647.1 - 0.0038 16.6 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase TFIIE_beta PF02186.15 VBB30648.1 - 2.1e-15 56.7 0.7 4.2e-15 55.8 0.1 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 VBB30648.1 - 1.3e-09 37.6 0.2 4.1e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 4HBT PF03061.22 VBB30649.1 - 7.3e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 VBB30649.1 - 0.014 15.7 0.0 0.017 15.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily SUI1 PF01253.22 VBB30650.1 - 4.5e-16 59.1 0.1 9.8e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 VBB30650.1 - 6e-14 52.5 0.1 2.9e-13 50.3 0.1 2.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 VBB30650.1 - 0.018 15.0 0.0 0.064 13.2 0.0 2.0 1 1 0 1 1 1 0 PUA domain MetOD1 PF18546.1 VBB30650.1 - 0.079 12.9 0.2 0.49 10.3 0.1 2.3 2 0 0 2 2 2 0 Metanogen output domain 1 zf-SNAP50_C PF12251.8 VBB30651.1 - 5.4e-53 179.7 2.2 8.2e-53 179.1 2.2 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal C1_1 PF00130.22 VBB30651.1 - 0.13 12.2 0.5 0.3 11.0 0.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AD PF07776.15 VBB30651.1 - 0.15 12.3 2.3 12 6.2 0.1 3.4 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) Fibrinogen_C PF00147.18 VBB30652.1 - 4.4e-46 157.5 9.9 6.2e-46 157.0 9.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Claudin_3 PF06653.11 VBB30652.1 - 0.036 14.0 0.7 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF4859 PF16151.5 VBB30652.1 - 0.056 13.3 1.6 4.9 7.1 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4859) 7TM_GPCR_Srd PF10317.9 VBB30652.1 - 0.21 10.7 2.9 0.19 10.9 0.2 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Profilin PF00235.19 VBB30653.1 - 2.3e-32 111.9 0.0 2.7e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Profilin Skp1_POZ PF03931.15 VBB30654.1 - 3.7e-12 46.2 0.0 5.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain AMNp_N PF10423.9 VBB30654.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus SH3_1 PF00018.28 VBB30655.1 - 1.5e-41 139.8 14.1 1.2e-17 63.3 0.1 4.8 5 1 0 5 5 5 3 SH3 domain SH3_9 PF14604.6 VBB30655.1 - 1.3e-39 133.8 4.7 7e-17 61.0 0.1 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 VBB30655.1 - 1.9e-29 101.1 4.5 9e-13 47.7 0.0 4.0 3 1 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 VBB30655.1 - 1.1e-08 35.2 4.4 0.011 16.0 0.0 4.0 4 0 0 4 4 4 3 Bacterial SH3 domain SH2 PF00017.24 VBB30655.1 - 1.4e-06 28.3 0.0 4.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain hSH3 PF14603.6 VBB30655.1 - 0.002 18.5 0.0 1.1 9.8 0.0 3.6 4 0 0 4 4 4 1 Helically-extended SH3 domain SH3_10 PF17902.1 VBB30655.1 - 0.0059 16.7 1.1 0.88 9.7 0.0 3.3 3 0 0 3 3 3 1 SH3 domain Peptidase_M14 PF00246.24 VBB30656.1 - 1.3e-53 182.7 0.1 2.7e-50 171.8 0.1 2.0 1 1 1 2 2 2 2 Zinc carboxypeptidase Na_H_Exchanger PF00999.21 VBB30657.1 - 1.9e-77 260.7 44.9 2.4e-77 260.3 44.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SHP PF03579.13 VBB30657.1 - 0.67 10.0 5.4 1.6 8.8 1.0 2.7 2 0 0 2 2 2 0 Small hydrophobic protein Lectin_C PF00059.21 VBB30658.1 - 2.2e-09 38.0 0.0 2.2e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 Lectin C-type domain G-7-MTase PF12803.7 VBB30658.1 - 0.12 11.6 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Ank_2 PF12796.7 VBB30660.1 - 1.7e-39 134.3 0.2 1.7e-14 54.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB30660.1 - 5e-37 125.8 3.2 1.8e-12 47.5 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB30660.1 - 6e-30 102.9 3.4 2.2e-10 40.6 0.3 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30660.1 - 4.5e-28 94.2 1.4 3.2e-06 27.0 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 VBB30660.1 - 9.8e-27 92.2 3.2 6.9e-08 32.6 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Sec20 PF03908.13 VBB30660.1 - 1.4e-13 50.6 1.5 1.4e-13 50.6 1.5 2.5 2 0 0 2 2 2 1 Sec20 Aminotran_1_2 PF00155.21 VBB30660.1 - 0.0067 15.7 1.2 1.3 8.1 0.7 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Mating_N PF12731.7 VBB30660.1 - 0.014 15.5 1.5 4 7.6 0.3 3.0 3 0 0 3 3 3 0 Mating-type protein beta 1 G-gamma PF00631.22 VBB30660.1 - 0.023 14.7 0.3 1.2 9.2 0.1 2.9 2 1 1 3 3 3 0 GGL domain V-SNARE PF05008.15 VBB30660.1 - 0.44 11.0 8.0 0.13 12.7 3.3 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3492 PF11997.8 VBB30660.1 - 6.2 6.5 8.4 2.9 7.6 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3492) UQ_con PF00179.26 VBB30661.1 - 1.7e-42 144.4 0.2 8.2e-42 142.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB30661.1 - 0.00044 19.9 0.0 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 VBB30661.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 VBB30661.1 - 0.06 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 UEV domain UBA PF00627.31 VBB30661.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain zf-H2C2_5 PF13909.6 VBB30662.1 - 0.0005 19.8 1.5 0.0005 19.8 1.5 5.7 6 0 0 6 6 6 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 VBB30662.1 - 0.0028 17.9 4.0 0.0028 17.9 4.0 4.6 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 VBB30662.1 - 0.027 15.3 35.1 0.85 10.6 1.2 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger PAP1 PF08601.10 VBB30662.1 - 0.1 12.3 6.1 0.056 13.2 1.7 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 zf_UBZ PF18439.1 VBB30662.1 - 0.16 11.6 0.0 0.16 11.6 0.0 4.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 VBB30662.1 - 0.19 12.2 32.2 0.17 12.4 0.9 6.0 6 0 0 6 6 6 0 Zinc-finger double domain zf-WRNIP1_ubi PF18279.1 VBB30662.1 - 0.31 11.8 0.1 0.31 11.8 0.1 3.5 4 0 0 4 4 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_2 PF12756.7 VBB30662.1 - 2.6 8.4 35.5 1 9.8 8.4 4.9 3 3 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Med27 PF11571.8 VBB30662.1 - 5.3 7.5 10.8 3.2 8.2 0.7 3.2 2 1 0 2 2 2 0 Mediator complex subunit 27 Actin_micro PF17003.5 VBB30662.1 - 7.5 5.6 16.3 6 5.9 1.8 3.4 2 1 0 3 3 3 0 Putative actin-like family NDUFB10 PF10249.9 VBB30663.1 - 3.4e-49 166.5 0.4 5.6e-49 165.8 0.4 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 LEDGF PF11467.8 VBB30663.1 - 0.49 10.0 2.2 3.6 7.2 0.7 2.2 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) PFK PF00365.20 VBB30664.1 - 8.7e-199 658.5 3.1 2.1e-108 362.0 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF2240 PF09999.9 VBB30664.1 - 0.063 12.9 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) DB PF01682.19 VBB30665.1 - 5.6e-24 84.3 11.1 1.1e-23 83.4 11.1 1.5 1 0 0 1 1 1 1 DB module Ribophorin_I PF04597.14 VBB30666.1 - 4.9e-119 398.4 4.3 6.1e-119 398.1 4.3 1.0 1 0 0 1 1 1 1 Ribophorin I ToxS PF17323.2 VBB30666.1 - 0.017 14.8 0.2 0.048 13.3 0.1 1.9 2 0 0 2 2 2 0 Trans-membrane regulatory protein ToxS Jnk-SapK_ap_N PF09744.9 VBB30668.1 - 8.3e-50 169.0 20.7 8.3e-50 169.0 20.7 4.3 4 1 0 4 4 4 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 VBB30668.1 - 2.3e-31 107.8 10.6 2.3e-31 107.8 10.6 3.9 3 1 0 3 3 3 1 JNK-interacting protein leucine zipper II ANAPC4_WD40 PF12894.7 VBB30668.1 - 1.3e-05 25.4 1.0 0.032 14.5 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Atg14 PF10186.9 VBB30668.1 - 0.0081 15.3 21.5 0.19 10.8 7.3 2.5 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Dynamin_N PF00350.23 VBB30668.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.3 4 0 0 4 4 4 0 Dynamin family TraH PF06122.11 VBB30668.1 - 0.26 10.5 3.2 1.9 7.7 3.2 2.4 1 1 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF1759 PF03564.15 VBB30668.1 - 3.3 7.6 8.5 0.87 9.5 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Cmc1 PF08583.10 VBB30669.1 - 5.4e-06 26.3 4.2 5.4e-06 26.3 4.2 1.6 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2167 PF09935.9 VBB30670.1 - 0.39 9.8 3.6 0.63 9.2 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Arm PF00514.23 VBB30671.1 - 0.0079 16.2 1.5 4.2 7.6 0.0 4.4 4 1 1 5 5 5 2 Armadillo/beta-catenin-like repeat Myb_Cef PF11831.8 VBB30672.1 - 4.5e-34 118.1 11.1 4.5e-34 118.1 11.1 4.4 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 VBB30672.1 - 1.5e-19 69.9 5.5 4.2e-11 42.9 1.8 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 VBB30672.1 - 8.8e-18 64.3 6.9 2.7e-12 46.8 2.9 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Fib_alpha PF08702.10 VBB30672.1 - 0.62 10.3 6.2 2.4 8.3 6.2 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.17 VBB30673.1 - 8.8e-08 31.7 5.6 0.019 15.0 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB30673.1 - 1.6e-06 28.3 5.3 0.0013 18.9 5.5 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB30673.1 - 5e-05 22.9 8.1 0.0034 17.1 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB30673.1 - 0.00019 21.3 4.4 0.69 10.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB30673.1 - 0.00094 19.6 4.3 0.0011 19.5 1.7 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB30673.1 - 0.0074 16.4 0.1 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30673.1 - 0.013 15.2 0.2 0.013 15.2 0.2 2.8 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 VBB30673.1 - 0.11 13.4 2.4 11 7.1 0.5 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30673.1 - 1.1 9.8 3.8 3.2 8.3 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LEM PF03020.15 VBB30674.1 - 6.6e-11 41.6 0.1 1.4e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 LEM domain Ank_2 PF12796.7 VBB30674.1 - 3.2e-07 30.8 0.1 7.4e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB30674.1 - 2.2e-06 27.8 0.0 5.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB30674.1 - 1.9e-05 24.9 0.4 0.00062 20.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 VBB30674.1 - 2.4e-05 24.8 0.1 7.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30674.1 - 7.2e-05 22.9 0.2 0.043 14.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat SGS PF05002.15 VBB30674.1 - 0.064 13.4 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 SGS domain TetR_C_33 PF13305.6 VBB30674.1 - 0.1 13.3 0.0 0.29 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DOMON PF03351.17 VBB30675.1 - 2.4e-06 27.8 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DHHC PF01529.20 VBB30675.1 - 0.062 13.4 5.8 0.11 12.7 5.8 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase ING PF12998.7 VBB30676.1 - 1.6e-21 76.8 3.0 3e-21 75.9 3.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 VBB30676.1 - 5.9e-06 26.1 11.7 1.2e-05 25.1 11.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 VBB30676.1 - 0.0019 17.7 3.4 0.0032 17.0 3.4 1.4 1 0 0 1 1 1 1 PHD-finger C9orf72-like PF15019.6 VBB30676.1 - 0.042 13.4 0.5 0.063 12.8 0.5 1.2 1 0 0 1 1 1 0 C9orf72-like protein family V_ATPase_I PF01496.19 VBB30676.1 - 0.13 10.1 1.8 0.16 9.8 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-HC5HC2H PF13771.6 VBB30676.1 - 0.16 12.2 6.5 0.55 10.5 6.5 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C4pol PF14260.6 VBB30676.1 - 2.7 8.5 8.5 1.5 9.4 1.3 2.8 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Memo PF01875.17 VBB30677.1 - 8.9e-76 254.6 0.1 1.2e-75 254.2 0.1 1.1 1 0 0 1 1 1 1 Memo-like protein Transketolase_N PF00456.21 VBB30678.1 - 0.11 11.4 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain CLU PF13236.6 VBB30679.1 - 2.4e-46 158.3 0.3 1.4e-43 149.3 0.0 2.2 1 1 1 2 2 2 2 Clustered mitochondria CLU_N PF15044.6 VBB30679.1 - 9.3e-11 41.9 3.2 1.3e-09 38.2 3.2 2.2 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 VBB30679.1 - 0.00013 22.0 0.0 0.00042 20.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Dpy19 PF10034.9 VBB30683.1 - 2e-114 383.2 31.9 6.6e-98 328.6 21.1 3.0 1 1 1 2 2 2 2 Q-cell neuroblast polarisation FERM_C PF09380.10 VBB30687.1 - 2.1e-21 76.1 0.0 4.8e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 VBB30687.1 - 4.6e-12 45.7 0.0 1.4e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 VBB30687.1 - 1.8e-09 38.0 0.0 3.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 FERM central domain Alpha-amylase PF00128.24 VBB30688.1 - 1.2e-39 136.8 0.6 1.7e-39 136.3 0.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 VBB30688.1 - 2e-22 78.6 2.3 3.4e-22 77.8 2.3 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Fic PF02661.18 VBB30689.1 - 3.9e-25 88.6 0.0 1.3e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family TPR_19 PF14559.6 VBB30689.1 - 0.00018 22.0 0.5 0.039 14.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB30689.1 - 0.0029 17.6 0.3 0.57 10.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30689.1 - 0.0041 17.8 1.6 3.5 8.7 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30689.1 - 0.0043 17.7 1.1 0.07 13.8 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB30689.1 - 0.017 14.9 0.1 0.25 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 VBB30689.1 - 0.026 14.6 0.3 1.8 8.8 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30689.1 - 0.098 13.1 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Atg8 PF02991.16 VBB30690.1 - 7.4e-40 135.3 0.2 1.1e-39 134.8 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 VBB30690.1 - 0.00015 22.1 0.1 0.00024 21.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cullin PF00888.22 VBB30691.1 - 3.5e-183 610.6 21.6 4.4e-183 610.3 21.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 VBB30691.1 - 6e-23 80.7 1.6 6e-23 80.7 1.6 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DEAD PF00270.29 VBB30692.1 - 4.2e-50 170.0 0.0 9e-50 168.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB30692.1 - 2.4e-24 85.8 0.0 3.2e-23 82.2 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB30692.1 - 7.6e-05 22.8 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 VBB30692.1 - 0.15 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Mon1 PF03164.14 VBB30693.1 - 5e-78 262.9 1.8 1.1e-77 261.9 1.8 1.5 1 0 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_L2 PF00181.23 VBB30693.1 - 2.9e-17 62.4 0.0 6.7e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.18 VBB30693.1 - 2.4e-06 27.7 0.0 9e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain CUB PF00431.20 VBB30694.1 - 1.4e-70 234.6 3.5 3.3e-32 111.1 0.1 3.1 3 0 0 3 3 3 3 CUB domain FXa_inhibition PF14670.6 VBB30694.1 - 9.2e-10 38.6 12.8 9.2e-10 38.6 12.8 2.1 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 VBB30694.1 - 9.2e-09 35.4 12.9 2.2e-08 34.2 12.9 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.7 VBB30694.1 - 4.4e-05 23.3 1.3 9.6e-05 22.2 0.4 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.7 VBB30694.1 - 0.00052 20.1 9.9 0.0021 18.2 9.9 2.0 1 0 0 1 1 1 1 EGF domain EGF PF00008.27 VBB30694.1 - 0.025 14.9 7.3 0.025 14.9 7.3 2.5 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 VBB30694.1 - 0.37 11.5 9.6 0.22 12.2 6.4 2.5 2 1 0 2 2 2 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 VBB30694.1 - 0.83 10.0 8.3 2.4 8.5 8.3 1.9 1 0 0 1 1 1 0 Pvs28 EGF domain IMS PF00817.20 VBB30695.1 - 6.8e-35 120.3 0.0 7.6e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family DUF1805 PF08827.11 VBB30695.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Rad51 PF08423.11 VBB30696.1 - 8.8e-28 97.2 0.0 1.1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 VBB30696.1 - 4.9e-07 29.5 0.0 1.1e-06 28.3 0.0 1.5 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 VBB30696.1 - 1.5e-05 24.5 0.1 3.2e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 KaiC RecA PF00154.21 VBB30696.1 - 0.00016 21.2 0.5 0.00077 19.0 0.5 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 VBB30696.1 - 0.00035 20.0 1.0 0.018 14.3 0.0 2.1 1 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 VBB30696.1 - 0.0036 17.6 0.1 0.0063 16.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 VBB30696.1 - 0.021 14.7 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CSM2 PF16834.5 VBB30696.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Shu complex component Csm2, DNA-binding ABC_tran PF00005.27 VBB30696.1 - 0.083 13.4 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 VBB30696.1 - 0.086 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 VBB30696.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 VBB30696.1 - 0.19 11.4 0.0 0.33 10.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Hus1 PF04005.12 VBB30697.1 - 7.8e-34 117.1 0.0 9.8e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein DUF4097 PF13349.6 VBB30697.1 - 0.0086 15.4 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Putative adhesin EF-hand_7 PF13499.6 VBB30698.1 - 6.4e-12 45.7 0.1 0.0001 22.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB30698.1 - 1.4e-10 40.0 0.2 0.00025 20.4 0.0 4.5 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 VBB30698.1 - 1.1e-09 37.4 0.2 0.0015 18.3 0.0 3.9 3 2 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 VBB30698.1 - 2e-08 34.0 0.2 0.0093 15.8 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 VBB30698.1 - 6.8e-07 29.5 0.0 0.02 15.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 VBB30698.1 - 0.019 15.0 0.0 6.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TFIID-31kDa PF02291.15 VBB30699.1 - 6.8e-41 139.2 0.0 9.2e-41 138.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 VBB30699.1 - 0.00012 22.4 0.1 0.00024 21.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 VBB30699.1 - 0.0029 17.7 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 VBB30699.1 - 0.0035 17.7 1.9 0.0038 17.6 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 VBB30699.1 - 0.0037 17.2 0.2 0.0093 16.0 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated BTB PF00651.31 VBB30699.1 - 0.013 15.7 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 BTB/POZ domain SGS PF05002.15 VBB30700.1 - 7.5e-31 106.1 4.9 1.4e-30 105.2 4.9 1.5 1 1 0 1 1 1 1 SGS domain CS PF04969.16 VBB30700.1 - 3.5e-05 24.7 0.2 0.00012 23.0 0.2 1.9 1 1 0 1 1 1 1 CS domain Proteasome PF00227.26 VBB30701.1 - 3.2e-56 189.8 0.0 5.4e-56 189.1 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 VBB30701.1 - 7.3e-10 38.3 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Glyco_hydro_20 PF00728.22 VBB30702.1 - 1.2e-10 41.3 0.0 5.3e-10 39.2 0.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Oxysterol_BP PF01237.18 VBB30703.1 - 9.9e-68 228.7 16.1 4.5e-48 164.0 0.0 5.2 2 1 1 3 3 3 3 Oxysterol-binding protein PH PF00169.29 VBB30703.1 - 1.3e-06 28.8 0.0 4.9e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 PH domain ExoD PF06055.12 VBB30703.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD HEAT_2 PF13646.6 VBB30705.1 - 0.0016 18.8 0.0 0.28 11.6 0.0 2.7 2 0 0 2 2 2 2 HEAT repeats Pkinase PF00069.25 VBB30706.1 - 1.4e-62 211.5 0.0 1.9e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 VBB30706.1 - 1.1e-35 121.6 0.1 1.1e-18 67.1 0.0 2.8 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 VBB30706.1 - 1.2e-27 96.8 0.0 2.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB30706.1 - 6.5e-05 21.9 0.0 0.00014 20.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 VBB30706.1 - 0.00028 20.3 0.0 0.00083 18.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like mTERF PF02536.14 VBB30706.1 - 0.022 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 mTERF SRF-TF PF00319.18 VBB30707.1 - 7.8e-25 86.1 0.4 1.3e-24 85.4 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GHD PF17834.1 VBB30707.1 - 0.043 13.9 1.1 0.095 12.8 0.1 2.0 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase CAF1A PF12253.8 VBB30708.1 - 1.8e-23 82.5 4.9 1.8e-23 82.5 4.9 4.8 4 1 1 5 5 5 1 Chromatin assembly factor 1 subunit A ThiF PF00899.21 VBB30708.1 - 0.064 12.6 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 ThiF family ALMT PF11744.8 VBB30708.1 - 1.6 7.5 21.6 2.7 6.7 21.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4650 PF15509.6 VBB30709.1 - 0.027 13.8 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Tannase PF07519.11 VBB30709.1 - 0.071 12.0 0.1 0.091 11.7 0.1 1.3 1 1 0 1 1 1 0 Tannase and feruloyl esterase DUF5441 PF17513.2 VBB30709.1 - 0.18 11.5 0.2 0.92 9.2 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5441) Oxidored_q5_N PF01059.17 VBB30710.1 - 8.5 6.5 11.8 0.15 12.1 2.6 2.5 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus ADK PF00406.22 VBB30712.1 - 4.8e-25 88.4 0.0 6.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 VBB30712.1 - 1.6e-18 67.5 0.0 2.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 VBB30712.1 - 0.025 14.5 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Herpes_UL4 PF03277.13 VBB30712.1 - 0.068 12.8 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family Innexin PF00876.18 VBB30713.1 - 1.3e-108 363.5 8.6 1.5e-108 363.2 8.6 1.0 1 0 0 1 1 1 1 Innexin DUF3394 PF11874.8 VBB30713.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) PTPS PF01242.19 VBB30713.1 - 0.04 13.9 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase NAD_Gly3P_dh_N PF01210.23 VBB30714.1 - 2e-45 154.6 0.1 3.5e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 VBB30714.1 - 3.5e-43 147.3 0.8 1.9e-42 144.9 0.2 2.2 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 VBB30714.1 - 0.0013 19.2 1.1 0.0085 16.7 0.1 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Glucodextran_N PF09137.11 VBB30714.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Glucodextranase, domain N PAS PF00989.25 VBB30714.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold NPR2 PF06218.11 VBB30715.1 - 4.9e-72 243.1 7.0 8.8e-57 192.8 6.3 3.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 PIG-F PF06699.11 VBB30715.1 - 1.9e-28 99.9 5.9 3.3e-28 99.0 5.9 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Afi1 PF07792.12 VBB30715.1 - 0.0095 16.4 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF5401 PF17380.2 VBB30715.1 - 0.19 9.7 0.0 0.27 9.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DsbD_2 PF13386.6 VBB30715.1 - 0.66 9.9 8.3 0.09 12.7 1.9 2.4 2 1 1 3 3 3 0 Cytochrome C biogenesis protein transmembrane region Pkinase PF00069.25 VBB30716.1 - 1.1e-53 182.3 0.0 3.2e-53 180.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 VBB30716.1 - 3.7e-49 167.8 0.0 7e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 VBB30716.1 - 8.9e-27 94.0 0.0 2.1e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 VBB30716.1 - 8.6e-12 44.8 4.7 1.8e-11 43.7 4.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) KELK PF15796.5 VBB30716.1 - 2.5e-10 40.7 17.4 2.5e-10 40.7 17.4 6.6 5 1 3 8 8 8 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DMPK_coil PF08826.10 VBB30716.1 - 1.2e-07 31.7 15.4 1.2e-07 31.7 15.4 6.1 4 2 2 7 7 7 1 DMPK coiled coil domain like Kinase-like PF14531.6 VBB30716.1 - 1.4e-06 27.9 7.7 8.8e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 VBB30716.1 - 0.021 15.3 0.5 0.11 13.0 0.0 2.6 2 1 0 2 2 2 0 PH domain Pkinase_C PF00433.24 VBB30716.1 - 0.066 13.9 0.1 0.24 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain ArdA PF07275.11 VBB30716.1 - 0.6 10.7 11.3 0.73 10.4 8.0 2.8 1 1 1 2 2 2 0 Antirestriction protein (ArdA) TFB6 PF17110.5 VBB30717.1 - 0.29 10.8 2.4 0.3 10.8 2.4 1.3 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CENP-B_dimeris PF09026.10 VBB30717.1 - 0.56 10.6 10.1 2 8.9 7.7 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Exostosin PF03016.15 VBB30718.1 - 1.6e-54 185.2 0.2 2.3e-54 184.6 0.2 1.2 1 0 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.10 VBB30718.1 - 5.7e-20 71.6 0.0 1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain zf-MIZ PF02891.20 VBB30718.1 - 0.09 12.5 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Vert_IL3-reg_TF PF06529.11 VBB30719.1 - 0.015 14.4 2.1 0.02 14.0 0.0 2.0 2 0 0 2 2 2 0 Vertebrate interleukin-3 regulated transcription factor Myosin_head PF00063.21 VBB30720.1 - 3e-213 709.9 11.4 1.4e-176 588.7 8.5 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.13 VBB30720.1 - 3.6e-18 65.9 0.7 1.2e-17 64.2 0.7 1.8 1 1 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 VBB30720.1 - 0.0018 17.9 0.2 0.0049 16.6 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zeta_toxin PF06414.12 VBB30720.1 - 0.065 12.5 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 VBB30720.1 - 0.089 13.1 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 VBB30720.1 - 0.11 12.0 0.2 8.1 5.9 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 VBB30720.1 - 0.14 12.6 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 VBB30720.1 - 0.16 12.5 0.1 0.64 10.5 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Swi3 PF07962.12 VBB30722.1 - 1.9e-18 66.2 0.1 4.2e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Snurportin1 PF11538.8 VBB30722.1 - 0.22 11.7 3.1 0.6 10.3 3.1 1.8 1 0 0 1 1 1 0 Snurportin1 HMG-CoA_red PF00368.18 VBB30723.1 - 2.4e-130 434.8 1.5 3e-130 434.5 1.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase V-set PF07686.17 VBB30724.1 - 1.2e-05 25.5 0.1 4.7e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ago_PAZ PF18309.1 VBB30724.1 - 0.014 16.1 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Argonaute PAZ domain Ig_2 PF13895.6 VBB30724.1 - 0.025 14.9 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 VBB30724.1 - 0.053 14.1 0.0 0.093 13.3 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 VBB30726.1 - 2.7e-41 139.5 0.1 1.1e-14 54.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB30726.1 - 2.3e-39 133.8 0.2 2.6e-16 60.0 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB30726.1 - 1.1e-28 99.2 0.0 5.9e-11 42.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB30726.1 - 5.7e-27 93.9 0.1 1.7e-12 47.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 VBB30726.1 - 6.7e-25 87.4 1.3 5.4e-06 26.5 0.0 4.8 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB30726.1 - 1.6e-06 28.4 0.5 0.092 13.2 0.0 3.9 3 2 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 VBB30726.1 - 4e-06 27.0 0.4 0.041 14.1 0.0 4.2 3 2 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 VBB30726.1 - 9e-06 25.7 0.3 0.13 12.2 0.1 3.4 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain Izumo-Ig PF16706.5 VBB30726.1 - 5.4e-05 23.2 0.1 2.2 8.4 0.0 3.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 VBB30726.1 - 7.1e-05 22.8 0.0 0.028 14.5 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 VBB30726.1 - 0.0018 18.6 0.1 0.0055 17.0 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Ig_6 PF18452.1 VBB30726.1 - 0.011 15.2 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB30726.1 - 0.11 12.6 0.0 3 7.9 0.0 2.9 3 0 0 3 3 3 0 C17orf99 Ig domain Patched PF02460.18 VBB30728.1 - 2.8e-89 300.3 26.1 2.9e-45 154.7 4.8 3.4 2 1 1 3 3 3 3 Patched family Sterol-sensing PF12349.8 VBB30728.1 - 4.4e-24 85.1 8.1 4.4e-24 85.1 8.1 4.5 5 1 1 6 6 6 1 Sterol-sensing domain of SREBP cleavage-activation U3_assoc_6 PF08640.11 VBB30729.1 - 5.2e-15 55.3 2.3 5.2e-15 55.3 2.3 2.9 1 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 VBB30729.1 - 0.00083 20.0 0.0 0.98 10.4 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Phospholip_A2_3 PF09056.11 VBB30729.1 - 5.6 7.6 7.5 1.8 9.2 1.0 2.7 2 1 1 3 3 3 0 Prokaryotic phospholipase A2 zf-C3HC4_2 PF13923.6 VBB30730.1 - 3.2e-10 39.7 9.5 3.2e-10 39.7 9.5 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB30730.1 - 7.7e-10 38.9 20.6 1.7e-09 37.8 8.5 2.9 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 VBB30730.1 - 2.8e-09 36.7 9.1 2.8e-09 36.7 9.1 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 VBB30730.1 - 1.6e-06 27.9 6.4 1.6e-06 27.9 6.4 3.7 2 1 0 2 2 2 1 PHD-finger zf-C3HC4_4 PF15227.6 VBB30730.1 - 4.2e-06 26.8 8.9 4.2e-06 26.8 8.9 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 VBB30730.1 - 1.2e-05 25.5 10.8 1.2e-05 25.5 10.8 3.4 3 1 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 VBB30730.1 - 2.6e-05 24.1 7.0 2.6e-05 24.1 7.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 VBB30730.1 - 3.8e-05 23.4 4.9 3.8e-05 23.4 4.9 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 VBB30730.1 - 0.00012 22.2 4.3 0.00012 22.2 4.3 2.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 VBB30730.1 - 0.00015 21.6 1.5 0.00033 20.5 1.5 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 VBB30730.1 - 0.006 16.6 9.6 0.047 13.7 2.3 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 VBB30730.1 - 0.016 14.8 4.1 0.016 14.8 4.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prim_Zn_Ribbon PF08273.12 VBB30730.1 - 0.065 13.5 0.0 0.065 13.5 0.0 3.4 4 0 0 4 4 3 0 Zinc-binding domain of primase-helicase DUF393 PF04134.12 VBB30730.1 - 0.091 14.1 1.3 2.1 9.7 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF393 Prok-RING_4 PF14447.6 VBB30730.1 - 0.18 11.7 20.8 0.6 10.0 9.0 3.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 VBB30730.1 - 2.1 8.2 14.5 6.3 6.6 7.8 2.8 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.6 VBB30730.1 - 2.8 8.0 21.8 0.034 14.1 8.0 3.4 2 2 0 2 2 2 0 zinc-RING finger domain Rubredoxin PF00301.20 VBB30730.1 - 6.2 6.9 8.7 0.75 9.9 0.4 3.0 3 0 0 3 3 3 0 Rubredoxin Pkinase PF00069.25 VBB30731.1 - 1.8e-69 234.0 0.0 2.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30731.1 - 4.1e-35 121.3 0.0 5.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB30731.1 - 3.6e-05 23.2 0.0 0.00011 21.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RRM_1 PF00076.22 VBB30732.1 - 3.5e-15 55.6 0.0 1.2e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Globin PF00042.22 VBB30732.1 - 0.015 15.9 0.1 0.036 14.6 0.1 1.7 1 0 0 1 1 1 0 Globin IFN-gamma PF00714.17 VBB30732.1 - 0.033 14.0 0.3 0.07 13.0 0.3 1.5 1 0 0 1 1 1 0 Interferon gamma BolA PF01722.18 VBB30733.1 - 4.8e-19 68.4 0.0 1.4e-18 66.9 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein Ank_5 PF13857.6 VBB30733.1 - 1e-16 60.7 0.0 3.6e-12 46.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACBP PF00887.19 VBB30733.1 - 2.3e-16 59.8 0.0 4.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 VBB30733.1 - 4.7e-15 55.9 0.0 9.3e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 VBB30733.1 - 1.9e-14 53.4 0.0 7.6e-06 26.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 VBB30733.1 - 8.1e-14 51.8 0.0 2.4e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30733.1 - 1.5e-13 49.5 0.0 5.7e-06 26.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat OST3_OST6 PF04756.13 VBB30734.1 - 1.2e-85 287.5 0.0 1.5e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4131 PF13567.6 VBB30734.1 - 0.0029 17.3 0.9 0.0066 16.1 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF3098 PF11297.8 VBB30734.1 - 0.19 11.4 5.2 15 5.3 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3098) Yip1 PF04893.17 VBB30734.1 - 0.27 10.9 3.5 2.4 7.9 3.7 2.1 1 1 0 1 1 1 0 Yip1 domain DUF3382 PF11862.8 VBB30734.1 - 0.32 11.3 4.0 0.48 10.7 1.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) zf-C2H2_jaz PF12171.8 VBB30735.1 - 4.2e-07 30.1 0.7 7.1e-07 29.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB30735.1 - 1.9e-05 24.9 0.7 3.2e-05 24.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 VBB30735.1 - 4.3e-05 23.2 1.6 8.5e-05 22.2 1.6 1.4 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 VBB30735.1 - 0.0035 17.4 1.8 0.0071 16.4 0.3 2.4 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins PDGLE PF13190.6 VBB30735.1 - 0.037 13.9 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 PDGLE domain zf-C2H2 PF00096.26 VBB30735.1 - 0.16 12.5 0.6 0.33 11.5 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Mitoc_L55 PF09776.9 VBB30735.1 - 6.6 6.5 12.0 1 9.1 3.5 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L55 HIP1_clath_bdg PF16515.5 VBB30735.1 - 9.2 7.0 14.8 0.32 11.6 7.4 2.1 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LRR_8 PF13855.6 VBB30736.1 - 1.2e-27 95.5 44.0 1.9e-09 37.2 8.3 4.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 VBB30736.1 - 4.2e-18 65.2 19.7 1.9e-07 31.3 3.3 4.7 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB30736.1 - 1e-10 40.6 18.6 1.3 9.9 0.7 8.1 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 VBB30736.1 - 0.00054 19.8 24.0 4.9 7.5 0.3 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 VBB30736.1 - 0.0019 17.7 9.1 0.21 11.1 2.4 2.6 1 1 1 3 3 3 2 Leucine-rich repeat NKWYS PF10364.9 VBB30736.1 - 0.0087 16.2 0.7 4.5 7.4 0.1 2.5 2 1 1 3 3 3 2 Putative capsular polysaccharide synthesis protein RsmF_methylt_CI PF17126.5 VBB30736.1 - 0.025 14.6 0.1 14 5.8 0.0 3.7 2 2 2 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain Cript PF10235.9 VBB30737.1 - 8.9e-28 96.7 7.8 8.9e-28 96.7 7.8 1.3 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 VBB30737.1 - 0.0018 18.5 12.1 0.0024 18.2 9.2 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 VBB30737.1 - 0.037 14.4 8.2 0.044 14.2 4.8 2.0 2 0 0 2 2 2 0 Rhodanase C-terminal Gin PF10764.9 VBB30737.1 - 0.28 11.2 7.3 13 5.8 0.1 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DZR PF12773.7 VBB30737.1 - 0.49 10.5 11.4 3.7 7.7 7.7 2.7 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 VBB30737.1 - 0.94 9.9 10.6 0.81 10.0 3.3 2.9 2 1 1 3 3 3 0 C1 domain zf-C3HC4_3 PF13920.6 VBB30737.1 - 1.3 8.9 14.6 13 5.7 0.7 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L37e PF01907.19 VBB30737.1 - 5.4 7.3 11.7 3 8.1 5.7 2.4 1 1 1 2 2 2 0 Ribosomal protein L37e NinF PF05810.12 VBB30737.1 - 9.8 6.1 10.3 8.6 6.3 0.3 3.0 2 1 1 3 3 3 0 NinF protein TBP PF00352.21 VBB30738.1 - 1.3e-22 79.6 1.8 4.7e-17 61.7 0.0 3.4 3 0 0 3 3 3 3 Transcription factor TFIID (or TATA-binding protein, TBP) tRNA-synt_2c PF01411.19 VBB30739.1 - 9.7e-222 737.4 0.0 1.3e-221 737.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 VBB30739.1 - 3.1e-14 52.8 0.5 7.9e-14 51.5 0.5 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 VBB30739.1 - 7.2e-14 52.4 4.4 7.2e-14 52.4 4.4 2.1 2 0 0 2 2 2 1 DHHA1 domain DUF4347 PF14252.6 VBB30739.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Pkinase PF00069.25 VBB30740.1 - 5.9e-66 222.5 0.0 9.3e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30740.1 - 2.6e-34 118.7 0.0 4.4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB30740.1 - 7.3e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB30740.1 - 1.2e-05 24.8 0.2 2.7e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB30740.1 - 0.0012 17.9 0.6 0.0026 16.7 0.6 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB30740.1 - 0.089 12.7 0.1 0.43 10.5 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Homeodomain PF00046.29 VBB30741.1 - 1.4e-22 79.2 8.1 2.6e-22 78.4 8.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB30741.1 - 0.0051 16.7 1.4 0.02 14.8 0.5 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 VBB30741.1 - 0.17 11.4 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HA2 PF04408.23 VBB30742.1 - 4.3e-16 59.1 0.8 5.1e-15 55.7 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) R3H PF01424.22 VBB30742.1 - 2.3e-14 53.1 1.6 2.2e-12 46.7 0.0 3.4 3 0 0 3 3 3 1 R3H domain Helicase_C PF00271.31 VBB30742.1 - 1.4e-13 51.2 0.2 8.3e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB30742.1 - 1.2e-09 38.1 0.5 2.3e-09 37.3 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 VBB30742.1 - 1.9e-06 28.2 0.0 6.2e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 VBB30742.1 - 0.0004 20.7 0.3 0.00078 19.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 VBB30742.1 - 0.0005 20.4 0.3 0.0014 18.9 0.3 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 VBB30742.1 - 0.0017 18.4 0.1 0.013 15.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 VBB30742.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.6 VBB30742.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 VBB30742.1 - 0.029 13.9 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 VBB30742.1 - 0.041 14.4 2.4 0.36 11.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 VBB30742.1 - 0.042 12.9 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Takusan PF04822.13 VBB30742.1 - 0.052 13.4 1.1 0.19 11.6 1.1 1.9 1 0 0 1 1 1 0 Takusan FtsK_SpoIIIE PF01580.18 VBB30742.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 VBB30742.1 - 0.12 11.3 0.2 0.27 10.1 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 VBB30742.1 - 0.14 12.7 0.0 0.46 11.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 VBB30742.1 - 0.72 9.8 7.7 0.21 11.6 1.2 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Med13_C PF06333.12 VBB30743.1 - 2.9 7.1 16.6 3.9 6.7 16.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Pkinase PF00069.25 VBB30744.1 - 2.1e-64 217.4 0.0 2.8e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30744.1 - 1.7e-31 109.5 0.0 2.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 VBB30744.1 - 1.1e-12 47.7 0.4 5.7e-12 45.4 0.0 2.4 3 0 0 3 3 3 1 PB1 domain C1_1 PF00130.22 VBB30744.1 - 1.4e-12 47.3 9.4 2.5e-12 46.5 9.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 VBB30744.1 - 3.8e-05 23.1 0.0 7.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 VBB30744.1 - 0.001 19.7 3.0 0.0022 18.6 3.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 VBB30744.1 - 0.0019 17.2 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 VBB30744.1 - 0.013 15.1 0.3 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 VBB30744.1 - 0.02 14.8 0.0 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_2 PF03107.16 VBB30744.1 - 0.55 10.6 6.9 1.1 9.7 6.9 1.5 1 0 0 1 1 1 0 C1 domain zf-RING_9 PF13901.6 VBB30744.1 - 0.67 9.9 5.9 1.2 9.0 5.9 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 VBB30744.1 - 0.9 9.2 6.2 1.9 8.1 6.2 1.5 1 0 0 1 1 1 0 PHD-finger AhpC-TSA PF00578.21 VBB30745.1 - 1.1e-35 122.3 0.0 1.7e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB30745.1 - 1.4e-16 60.6 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 VBB30745.1 - 1.1e-12 47.5 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin ECH_1 PF00378.20 VBB30746.1 - 1.2e-38 132.9 0.0 5.8e-38 130.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 VBB30746.1 - 1.7e-24 86.9 0.0 6.6e-24 85.0 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 VBB30748.1 - 3.7e-100 335.9 29.4 4.7e-97 325.7 29.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB30748.1 - 9.1e-19 67.6 32.6 2.6e-18 66.1 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily G-alpha PF00503.20 VBB30750.1 - 2e-22 79.8 0.2 2.1e-22 79.8 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 VBB30750.1 - 0.0033 16.9 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein Rad17 PF03215.15 VBB30750.1 - 0.0073 16.2 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain Bombinin PF05298.11 VBB30750.1 - 0.0083 15.8 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Bombinin Arf PF00025.21 VBB30750.1 - 0.0089 15.5 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DASH_Dad1 PF08649.10 VBB30750.1 - 0.048 13.9 0.1 0.091 13.0 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 AAA_29 PF13555.6 VBB30750.1 - 0.049 13.4 0.0 0.073 12.8 0.0 1.4 1 1 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 VBB30750.1 - 0.064 12.4 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 VBB30750.1 - 0.068 13.2 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 VBB30750.1 - 0.075 13.5 0.0 0.083 13.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 VBB30750.1 - 0.1 12.9 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RPN7 PF10602.9 VBB30751.1 - 1.2e-37 129.3 1.5 2.3e-37 128.4 1.5 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 VBB30751.1 - 2.6e-11 44.0 1.3 5.6e-11 42.9 0.6 1.9 2 0 0 2 2 2 1 PCI domain MAPKK1_Int PF08923.10 VBB30751.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting CBAH PF02275.18 VBB30754.1 - 1.7e-12 47.7 0.2 3.6e-12 46.6 0.1 1.6 1 1 1 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 VBB30754.1 - 6e-11 42.5 2.5 1.9e-10 40.9 2.4 1.9 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAT PF03417.16 VBB30754.1 - 0.00075 19.3 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Bacillus_HBL PF05791.11 VBB30755.1 - 0.0056 16.5 2.2 0.0056 16.5 2.2 9.6 6 4 5 11 11 11 5 Bacillus haemolytic enterotoxin (HBL) DUF2672 PF10878.8 VBB30755.1 - 0.029 14.3 0.3 0.099 12.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Turandot PF07240.11 VBB30755.1 - 0.92 9.5 7.9 10 6.2 0.1 4.4 4 0 0 4 4 4 0 Stress-inducible humoral factor Turandot PNP_UDP_1 PF01048.20 VBB30756.1 - 7.7e-21 74.4 0.1 8.8e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily FAIM1 PF06905.13 VBB30757.1 - 1.3e-76 256.2 4.3 1.5e-76 256.0 4.3 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DCP2 PF05026.13 VBB30758.1 - 8.1e-28 96.6 0.6 1.8e-27 95.5 0.6 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 VBB30758.1 - 9.1e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1030 PF06270.11 VBB30758.1 - 0.062 13.1 0.5 0.15 11.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Pyr_redox_2 PF07992.14 VBB30759.1 - 6.9e-65 219.2 7.0 8.1e-65 218.9 5.9 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 VBB30759.1 - 1.4e-41 141.2 0.1 6.5e-41 139.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 VBB30759.1 - 3.8e-16 59.4 9.1 2.6e-14 53.5 1.6 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 VBB30759.1 - 1.3e-11 44.4 1.5 2.3e-11 43.5 1.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 VBB30759.1 - 4.7e-10 39.4 10.2 3.4e-09 36.6 0.2 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 VBB30759.1 - 1.1e-07 32.0 1.6 9.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 VBB30759.1 - 4e-07 29.5 0.7 4e-07 29.5 0.7 3.3 3 1 1 4 4 4 1 FAD binding domain GIDA PF01134.22 VBB30759.1 - 8.3e-06 25.1 11.9 3.1e-05 23.2 5.5 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 VBB30759.1 - 1e-05 24.4 10.2 0.00037 19.3 0.7 3.7 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 VBB30759.1 - 0.00013 21.2 0.8 0.4 9.8 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 VBB30759.1 - 0.00016 21.1 5.9 0.012 14.9 0.4 3.3 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 VBB30759.1 - 0.00018 20.9 6.1 0.028 13.7 0.4 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 VBB30759.1 - 0.0047 16.0 1.6 0.0092 15.1 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 VBB30759.1 - 0.033 13.8 14.4 0.71 9.4 0.1 4.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.17 VBB30759.1 - 0.038 13.2 0.1 0.038 13.2 0.1 2.1 2 1 1 3 3 3 0 Thi4 family XdhC_C PF13478.6 VBB30759.1 - 0.041 14.4 0.2 8.7 6.9 0.1 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain GFO_IDH_MocA PF01408.22 VBB30759.1 - 0.22 12.3 1.1 1e+02 3.8 0.3 3.3 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 VBB30759.1 - 0.41 10.5 5.1 0.74 9.7 0.8 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 VBB30759.1 - 0.87 9.1 4.9 12 5.4 0.3 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ion_trans_2 PF07885.16 VBB30760.1 - 1.1e-31 108.7 19.2 1.6e-17 63.2 4.6 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 VBB30760.1 - 6.8e-07 28.8 8.0 0.00031 20.0 0.3 2.3 2 0 0 2 2 2 2 Ion transport protein Shisa PF13908.6 VBB30760.1 - 0.012 15.9 0.7 0.021 15.1 0.1 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ras PF00071.22 VBB30761.1 - 4.8e-31 107.5 0.0 1.3e-30 106.1 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB30761.1 - 2.2e-13 50.5 0.0 5.9e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 VBB30761.1 - 1e-05 25.8 0.5 9.4e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 SOCS box Arf PF00025.21 VBB30761.1 - 0.028 13.9 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family WD40 PF00400.32 VBB30762.1 - 4.9e-43 144.3 18.1 1.4e-07 32.1 0.5 11.8 12 0 0 12 12 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30762.1 - 2.5e-24 85.4 2.1 3.2e-07 30.5 0.0 9.0 3 3 7 10 10 10 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB30762.1 - 2.1e-13 50.6 1.1 7.8e-05 22.6 0.1 4.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 VBB30762.1 - 5.9e-07 28.6 0.9 0.65 8.7 0.0 5.2 5 1 0 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.14 VBB30762.1 - 1.5e-06 27.5 0.1 0.00026 20.2 0.1 3.1 3 0 0 3 3 3 1 Coatomer WD associated region PD40 PF07676.12 VBB30762.1 - 2.1e-06 27.5 17.2 1.8 8.6 0.0 7.5 10 0 0 10 10 8 3 WD40-like Beta Propeller Repeat HPS3_N PF14761.6 VBB30762.1 - 0.00028 20.5 0.0 0.017 14.7 0.0 3.6 4 1 1 5 5 5 1 Hermansky-Pudlak syndrome 3 Gmad1 PF10647.9 VBB30762.1 - 0.00086 19.1 0.0 0.048 13.4 0.0 3.1 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 VBB30762.1 - 0.00096 18.2 0.2 0.59 9.0 0.0 4.3 3 2 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 VBB30762.1 - 0.0028 15.7 0.0 0.054 11.5 0.0 2.5 3 0 0 3 3 3 1 IKI3 family Lactonase PF10282.9 VBB30762.1 - 0.0031 16.8 0.1 1.1 8.5 0.0 3.3 3 1 1 4 4 4 1 Lactonase, 7-bladed beta-propeller RAB3GAP2_N PF14655.6 VBB30762.1 - 0.021 14.1 0.0 0.76 9.0 0.0 3.2 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 VBB30762.1 - 0.021 14.1 0.9 2.1 7.6 0.0 4.0 4 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal SGL PF08450.12 VBB30762.1 - 0.025 14.2 0.1 0.3 10.6 0.1 2.7 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region TFIIIC_delta PF12657.7 VBB30762.1 - 0.095 12.6 5.4 5.7 6.8 0.0 4.2 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Rav1p_C PF12234.8 VBB30762.1 - 0.2 10.0 0.1 8.3 4.7 0.1 2.6 3 0 0 3 3 3 0 RAVE protein 1 C terminal WDCP PF15390.6 VBB30762.1 - 0.78 8.0 5.7 0.51 8.7 0.5 2.4 2 1 1 3 3 3 0 WD repeat and coiled-coil-containing protein family VWA PF00092.28 VBB30763.1 - 5e-59 199.5 1.2 3e-31 109.0 0.1 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 VBB30763.1 - 3.2e-30 104.9 0.2 1.2e-14 54.8 0.0 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 VBB30763.1 - 1.8e-15 57.0 0.2 2.8e-08 33.4 0.1 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA_3 PF13768.6 VBB30763.1 - 1.3e-06 28.5 0.0 0.051 13.5 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF1194 PF06707.11 VBB30763.1 - 0.00011 21.4 0.1 0.00094 18.4 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1194) vWA-TerF-like PF10138.9 VBB30763.1 - 0.0026 17.9 0.2 0.14 12.3 0.1 2.7 2 1 0 2 2 2 1 vWA found in TerF C terminus COMPASS-Shg1 PF05205.12 VBB30764.1 - 7.9e-10 39.4 0.1 2.1e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 TelA PF05816.11 VBB30764.1 - 0.0092 15.1 0.2 0.012 14.7 0.2 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF4844 PF16133.5 VBB30764.1 - 0.022 15.3 0.1 0.036 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) DUF2608 PF11019.8 VBB30764.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Metallophos PF00149.28 VBB30765.1 - 1.2e-18 68.4 1.6 1.6e-18 68.0 1.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB30765.1 - 9.6e-09 35.6 0.2 8.7e-08 32.5 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HMG_CoA_synt_N PF01154.17 VBB30766.1 - 3.4e-71 238.7 0.2 5.3e-71 238.1 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 VBB30766.1 - 3.3e-51 174.6 1.0 3.4e-30 105.6 0.3 2.1 1 1 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ADIP PF11559.8 VBB30768.1 - 0.00027 21.1 5.6 0.00027 21.1 5.6 3.8 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding AAA_16 PF13191.6 VBB30768.1 - 0.00056 20.3 1.1 0.2 12.0 0.1 3.0 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.29 VBB30768.1 - 0.0017 18.8 0.0 0.0046 17.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 VBB30768.1 - 0.004 17.2 0.1 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 VBB30768.1 - 0.0048 17.0 0.0 0.0048 17.0 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 VBB30768.1 - 0.013 15.4 0.0 0.049 13.5 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 VBB30768.1 - 0.04 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 VBB30768.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 VBB30768.1 - 0.24 11.7 3.6 1.5 9.1 0.4 3.5 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 VBB30768.1 - 0.27 11.8 0.0 0.27 11.8 0.0 3.5 4 0 0 4 4 4 0 ABC transporter DUF866 PF05907.13 VBB30769.1 - 3.6e-48 163.4 1.0 5.6e-48 162.8 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) MMR_HSR1 PF01926.23 VBB30769.1 - 2.1e-16 60.0 0.2 6.5e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 VBB30769.1 - 5.9e-10 39.7 0.4 1.4e-09 38.5 0.4 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 VBB30769.1 - 2.9e-07 31.0 0.2 7.1e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region Dynamin_N PF00350.23 VBB30769.1 - 0.006 16.6 0.0 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 VBB30769.1 - 0.019 14.5 0.0 0.046 13.2 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 VBB30769.1 - 0.14 12.1 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Ribosomal_L33 PF00471.20 VBB30769.1 - 0.32 11.5 3.2 0.65 10.5 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein L33 TatD_DNase PF01026.21 VBB30771.1 - 5.3e-56 189.8 0.0 6e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Med15 PF09606.10 VBB30772.1 - 6.5e-36 124.4 49.9 4.1e-19 68.8 0.0 4.8 2 1 2 4 4 4 3 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.5 VBB30772.1 - 9.8e-05 22.3 0.0 0.00035 20.5 0.0 2.0 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 VBB30772.1 - 0.064 13.5 0.5 0.39 11.0 0.3 2.4 2 1 0 2 2 2 0 KIX domain Helicase_C PF00271.31 VBB30773.1 - 1.9e-28 99.0 0.0 2.7e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain STAT_int PF02865.17 VBB30774.1 - 0.046 14.2 0.1 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 STAT protein, protein interaction domain UPF0029 PF01205.19 VBB30775.1 - 1.7e-30 105.4 0.1 3e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 VBB30775.1 - 1.4e-12 47.9 3.7 6.7e-11 42.5 3.7 2.4 1 1 0 1 1 1 1 RWD domain DUF2922 PF11148.8 VBB30775.1 - 0.095 12.4 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Evr1_Alr PF04777.13 VBB30776.1 - 8.4e-21 74.3 0.6 3.4e-20 72.4 0.6 2.1 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 VBB30776.1 - 4.1e-10 39.6 0.1 2.5e-08 33.8 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin QSOX_Trx1 PF18108.1 VBB30776.1 - 4.9e-08 33.1 0.2 2.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 QSOX Trx-like domain FAD_SOX PF18371.1 VBB30776.1 - 5.5e-08 33.1 0.1 1.7e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin_8 PF13905.6 VBB30776.1 - 0.0026 18.1 7.2 0.026 14.8 0.0 3.9 3 1 1 4 4 4 1 Thioredoxin-like DnaB PF00772.21 VBB30776.1 - 0.042 13.9 0.2 0.079 13.0 0.2 1.4 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain UDPGT PF00201.18 VBB30777.1 - 1.1e-67 229.0 0.1 1.3e-67 228.8 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 VBB30777.1 - 3.7e-06 27.0 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain TPR_1 PF00515.28 VBB30778.1 - 3.4e-23 80.4 13.3 6.3e-10 38.5 0.5 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB30778.1 - 1.4e-19 68.5 9.7 2e-07 30.6 0.5 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30778.1 - 4.2e-18 64.7 7.7 5.4e-06 26.0 1.3 4.0 3 1 1 4 4 4 3 TPR repeat SGTA_dimer PF16546.5 VBB30778.1 - 6.5e-16 57.9 3.4 9.7e-16 57.3 0.4 2.3 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_8 PF13181.6 VBB30778.1 - 3.4e-11 42.4 9.3 4.5e-06 26.5 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB30778.1 - 2.4e-10 39.7 5.5 4.5e-05 23.2 0.3 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB30778.1 - 1.3e-09 38.2 6.6 3.4e-08 33.6 2.8 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30778.1 - 5.8e-08 32.9 4.2 0.019 15.8 0.1 4.0 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30778.1 - 5.3e-07 30.2 3.0 0.0018 18.9 2.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30778.1 - 5.9e-07 29.4 7.1 0.0075 16.6 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 VBB30778.1 - 8.1e-06 25.2 2.6 0.11 12.0 0.2 3.4 3 0 0 3 3 3 2 SHNi-TPR TPR_15 PF13429.6 VBB30778.1 - 2.3e-05 23.8 0.7 0.0022 17.3 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB30778.1 - 4.4e-05 23.2 4.4 0.03 14.2 0.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB30778.1 - 9.9e-05 22.8 2.1 9.9e-05 22.8 2.1 2.9 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB30778.1 - 0.0029 17.7 3.6 0.21 11.8 2.6 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB30778.1 - 0.016 15.3 7.4 0.083 13.0 0.7 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.12 VBB30778.1 - 0.035 13.8 4.5 0.26 11.0 0.3 3.4 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 RNA_pol_Rpb6 PF01192.22 VBB30778.1 - 0.052 13.5 0.5 0.15 12.0 0.2 1.9 2 0 0 2 2 1 0 RNA polymerase Rpb6 P-mevalo_kinase PF04275.14 VBB30778.1 - 0.09 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Phosphomevalonate kinase BTAD PF03704.17 VBB30778.1 - 0.13 12.7 3.1 0.64 10.4 2.8 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_21 PF09976.9 VBB30778.1 - 1.2 8.8 6.1 2.7 7.7 1.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 VBB30778.1 - 1.6 9.5 4.2 1.5 9.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 VBB30778.1 - 2.4 8.2 7.6 0.51 10.3 1.1 2.9 3 0 0 3 3 3 0 Spore germination GerD central core domain STI1 PF17830.1 VBB30778.1 - 5 7.1 15.6 0.29 11.1 7.9 2.6 2 0 0 2 2 2 0 STI1 domain RICTOR_N PF14664.6 VBB30780.1 - 5.4e-23 81.6 2.9 6.2e-23 81.4 2.9 1.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term CBM_21 PF03370.13 VBB30781.1 - 5.9e-09 36.1 7.4 1.5e-05 25.1 1.3 2.9 2 1 1 3 3 3 2 Carbohydrate/starch-binding module (family 21) CDC13_N PF16853.5 VBB30781.1 - 0.0059 16.2 1.2 0.03 13.9 0.5 2.1 2 0 0 2 2 2 1 Cell division control protein 13 N-terminus CBM53 PF16760.5 VBB30781.1 - 0.0069 17.0 0.1 0.017 15.7 0.1 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) RMMBL PF07521.12 VBB30781.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain V-SNARE_C PF12352.8 VBB30782.1 - 2.2e-10 40.6 3.9 6.5e-10 39.2 3.9 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 VBB30782.1 - 4.6e-10 39.7 9.3 1e-09 38.7 4.2 3.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 VBB30782.1 - 0.00034 20.5 3.2 0.0004 20.2 1.6 1.9 2 1 0 2 2 2 1 Sec20 DUF4164 PF13747.6 VBB30782.1 - 1 9.7 10.8 0.58 10.5 5.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) MSC PF09402.10 VBB30782.1 - 4.5 6.6 7.1 0.63 9.4 1.8 1.8 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain Ribosomal_S7 PF00177.21 VBB30783.1 - 3.9e-28 98.0 0.1 4.7e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CDI PF02234.19 VBB30784.1 - 7.2e-13 48.5 0.0 1.6e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor CDI PF02234.19 VBB30785.1 - 7.5e-08 32.4 0.5 1.8e-07 31.2 0.5 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor VirB8 PF04335.13 VBB30786.1 - 0.048 13.5 0.8 0.071 12.9 0.8 1.2 1 0 0 1 1 1 0 VirB8 protein MRF_C2 PF13888.6 VBB30787.1 - 1.8e-35 121.9 0.1 1.8e-35 121.9 0.1 3.0 3 0 0 3 3 3 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.12 VBB30787.1 - 3.1e-22 79.7 0.9 3.1e-22 79.7 0.9 4.0 3 1 0 3 3 3 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 VBB30787.1 - 7.7e-18 63.4 0.1 1.5e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 VBB30787.1 - 1.4e-12 47.8 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase EPL1 PF10513.9 VBB30787.1 - 1.4 9.2 18.9 0.95 9.8 5.3 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Hep_59 PF07052.11 VBB30787.1 - 5.7 7.7 15.1 2.4 9.0 2.4 3.2 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Evr1_Alr PF04777.13 VBB30788.1 - 3.7e-19 69.1 1.6 1.2e-18 67.4 0.2 2.3 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 VBB30788.1 - 4.3e-17 62.0 0.1 2.3e-15 56.5 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin QSOX_Trx1 PF18108.1 VBB30788.1 - 0.00037 20.7 0.1 0.0021 18.2 0.0 2.3 3 0 0 3 3 3 1 QSOX Trx-like domain Thioredoxin_8 PF13905.6 VBB30788.1 - 0.0012 19.1 0.3 0.0053 17.1 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like FAD_SOX PF18371.1 VBB30788.1 - 0.0075 16.6 0.0 0.14 12.5 0.0 2.4 1 1 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF1186 PF06685.11 VBB30788.1 - 0.14 11.6 0.0 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) RasGEF PF00617.19 VBB30789.1 - 3e-51 174.1 0.1 6.6e-51 173.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain PDZ PF00595.24 VBB30789.1 - 3.5e-13 49.7 0.1 8.6e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain RasGEF_N PF00618.20 VBB30789.1 - 9.7e-11 41.8 0.7 1.8e-09 37.8 0.7 2.6 1 1 0 1 1 1 1 RasGEF N-terminal motif PDZ_6 PF17820.1 VBB30789.1 - 4e-10 39.4 0.0 9.5e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RA PF00788.23 VBB30789.1 - 1.7e-08 35.0 0.1 5e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.29 VBB30789.1 - 4.7e-08 33.0 0.0 0.0064 16.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 VBB30789.1 - 1.9e-05 24.9 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Cupin_2 PF07883.11 VBB30789.1 - 0.052 13.3 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.12 VBB30789.1 - 0.11 12.3 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) BHD_3 PF10405.9 VBB30790.1 - 5.3e-25 87.6 0.0 1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 VBB30790.1 - 3.3e-18 65.8 0.8 3.3e-18 65.8 0.8 3.2 3 1 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 VBB30790.1 - 2.8e-15 55.9 0.5 9.6e-15 54.2 0.3 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 VBB30790.1 - 1.1e-06 29.5 0.1 1.1e-06 29.5 0.1 2.9 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 BURP PF03181.15 VBB30790.1 - 0.23 11.0 4.2 0.4 10.2 4.2 1.3 1 0 0 1 1 1 0 BURP domain Pkinase PF00069.25 VBB30791.1 - 7.5e-73 245.1 0.0 8.9e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30791.1 - 1.2e-42 146.0 0.0 1.5e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB30791.1 - 7.9e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 VBB30791.1 - 0.015 15.0 0.3 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 VBB30791.1 - 0.071 11.9 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB30791.1 - 0.098 11.7 0.3 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 VBB30791.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL An_peroxidase PF03098.15 VBB30792.1 - 2.6e-19 69.2 0.6 3.1e-19 69.0 0.6 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PHD PF00628.29 VBB30793.1 - 8.6e-22 76.8 56.4 5.5e-09 35.8 11.1 7.5 6 1 1 7 7 7 4 PHD-finger SET PF00856.28 VBB30793.1 - 9.4e-18 65.2 3.9 1.5e-17 64.5 0.1 3.4 3 1 0 3 3 3 1 SET domain FYRN PF05964.14 VBB30793.1 - 1.8e-17 62.9 0.1 5e-17 61.5 0.1 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 VBB30793.1 - 9e-17 61.0 0.0 2.1e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus HMG_box_2 PF09011.10 VBB30793.1 - 0.0092 16.5 3.3 0.0092 16.5 3.3 2.8 3 0 0 3 3 3 1 HMG-box domain PHD_2 PF13831.6 VBB30793.1 - 0.059 12.9 27.1 0.15 11.7 2.8 5.4 4 0 0 4 4 4 0 PHD-finger DUF3450 PF11932.8 VBB30793.1 - 0.53 9.5 4.7 1.2 8.4 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HMG_box PF00505.19 VBB30793.1 - 0.9 10.0 11.4 0.022 15.2 2.7 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box zf-PHD-like PF15446.6 VBB30793.1 - 1.4 8.5 32.4 0.0083 15.8 4.6 4.2 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain SIP1 PF04938.12 VBB30794.1 - 2.1e-46 158.4 0.1 2.5e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Y_phosphatase PF00102.27 VBB30795.1 - 5.5e-40 137.4 0.3 1.2e-39 136.2 0.3 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB30795.1 - 4.3e-05 23.3 0.0 0.00016 21.4 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB30795.1 - 0.0051 16.8 2.4 0.0076 16.2 0.0 2.3 2 1 0 2 2 2 1 Tyrosine phosphatase family SMAP PF15477.6 VBB30795.1 - 0.088 13.8 1.9 0.32 12.0 1.9 2.1 1 0 0 1 1 1 0 Small acidic protein family PTPlike_phytase PF14566.6 VBB30795.1 - 0.089 12.9 0.0 0.089 12.9 0.0 2.7 2 1 1 3 3 3 0 Inositol hexakisphosphate FAM199X PF15814.5 VBB30795.1 - 2.1 7.3 20.1 0.26 10.3 13.6 2.3 2 1 0 3 3 3 0 Protein family FAM199X Filamin PF00630.19 VBB30796.1 - 5.9e-175 569.9 13.2 6.7e-16 59.0 0.0 19.6 20 0 0 20 20 20 17 Filamin/ABP280 repeat CH PF00307.31 VBB30796.1 - 6.4e-34 116.4 0.1 4.4e-20 71.9 0.7 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 VBB30796.1 - 6.8e-12 45.2 0.5 0.15 12.0 0.0 8.5 10 0 0 10 10 10 3 Y_Y_Y domain DUF5060 PF16586.5 VBB30796.1 - 5e-07 30.0 0.0 8.6 6.8 0.0 8.2 10 0 0 10 10 10 1 Domain of unknown function (DUF5060) Invasin_D3 PF09134.10 VBB30796.1 - 2.3e-05 24.6 0.1 14 6.1 0.0 6.6 6 0 0 6 6 6 1 Invasin, domain 3 DUF4198 PF10670.9 VBB30796.1 - 0.00039 20.8 0.0 0.29 11.5 0.0 5.1 5 2 1 6 6 6 1 Domain of unknown function (DUF4198) CAMSAP_CH PF11971.8 VBB30796.1 - 0.0081 16.0 0.0 5 7.0 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain Big_3_5 PF16640.5 VBB30796.1 - 0.028 14.6 3.4 20 5.4 0.0 5.6 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 3) MspA PF09203.11 VBB30796.1 - 0.07 13.0 0.2 0.25 11.2 0.2 1.9 1 0 0 1 1 1 0 MspA ETX_MTX2 PF03318.13 VBB30797.1 - 0.0021 17.9 2.3 0.0021 17.9 2.3 1.9 1 1 1 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Peptidase_C1 PF00112.23 VBB30798.1 - 5.2e-42 144.4 0.0 1.2e-41 143.2 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 VBB30798.1 - 1.2e-10 41.7 0.8 2.9e-10 40.4 0.8 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cystatin PF00031.21 VBB30798.1 - 2.8e-08 33.9 0.1 9.7e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 Cystatin domain Kazal_2 PF07648.15 VBB30799.1 - 4.1e-58 193.3 97.8 8.1e-11 41.9 1.1 11.5 11 0 0 11 11 11 10 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 VBB30799.1 - 7e-45 150.8 106.3 3.4e-07 30.2 2.3 12.0 11 1 0 11 11 11 11 Kazal-type serine protease inhibitor domain ANAPC1 PF12859.7 VBB30800.1 - 0.057 14.0 8.4 0.11 13.0 0.1 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 VBB30800.1 - 2.5 8.7 12.4 13 6.5 0.3 5.0 5 0 0 5 5 5 0 Proteasome/cyclosome repeat GYF PF02213.16 VBB30801.1 - 5e-15 54.9 0.7 8.7e-15 54.1 0.7 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 VBB30801.1 - 0.0041 16.9 0.2 0.01 15.6 0.2 1.7 1 0 0 1 1 1 1 GYF domain 2 Paf1 PF03985.13 VBB30802.1 - 9.6e-111 370.8 25.3 1.7e-75 254.7 0.3 3.5 2 1 1 3 3 3 2 Paf1 FtsH_ext PF06480.15 VBB30802.1 - 0.14 12.6 0.0 0.55 10.6 0.0 2.1 1 1 0 1 1 1 0 FtsH Extracellular Motile_Sperm PF00635.26 VBB30803.1 - 6.2e-13 48.6 0.1 1.3e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ArgoN PF16486.5 VBB30803.1 - 1.8e-10 41.6 0.0 3.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute Dermcidin PF15291.6 VBB30803.1 - 0.026 15.1 0.6 0.06 13.9 0.6 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide PMSI1 PF15322.6 VBB30803.1 - 0.03 13.8 2.6 0.051 13.0 2.6 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Motile_Sperm PF00635.26 VBB30804.1 - 2.2e-12 46.8 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Pkinase PF00069.25 VBB30805.1 - 9.1e-21 74.4 0.1 1e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30805.1 - 3e-14 53.0 0.0 3.5e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB30805.1 - 0.0013 18.8 0.0 0.15 11.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 VBB30805.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 VBB30805.1 - 0.059 13.0 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hydrolase_like PF13242.6 VBB30806.1 - 2.6e-17 62.7 0.0 7.1e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 VBB30806.1 - 1.2e-15 57.4 0.0 5.3e-15 55.4 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 VBB30806.1 - 1.6e-05 25.1 0.1 0.00021 21.4 0.0 2.4 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB30806.1 - 0.00092 19.6 0.1 0.0098 16.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DIL PF01843.19 VBB30807.1 - 1.1e-25 89.9 1.1 1.1e-25 89.9 1.1 2.8 3 1 1 4 4 4 1 DIL domain SNAPc19 PF15497.6 VBB30807.1 - 0.01 16.3 0.4 0.01 16.3 0.4 2.6 3 0 0 3 3 3 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 SAM_3 PF18016.1 VBB30807.1 - 0.02 14.7 0.2 0.057 13.2 0.2 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TolA_bind_tri PF16331.5 VBB30807.1 - 0.02 15.0 1.4 0.02 15.0 1.4 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation Mod_r PF07200.13 VBB30807.1 - 0.023 14.8 0.7 0.023 14.8 0.7 3.2 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Troponin PF00992.20 VBB30807.1 - 0.19 12.0 6.9 1.5 9.1 0.1 2.9 4 0 0 4 4 4 0 Troponin Cluap1 PF10234.9 VBB30807.1 - 1.8 7.9 7.3 0.15 11.4 0.9 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 Uso1_p115_C PF04871.13 VBB30807.1 - 2.1 8.7 10.9 12 6.3 0.2 3.0 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region E3_UbLigase_R4 PF13764.6 VBB30808.1 - 5.7e-228 759.1 13.5 8.5e-227 755.2 13.5 2.6 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DUF3394 PF11874.8 VBB30808.1 - 0.0057 16.4 0.9 3.6 7.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3394) CTU2 PF10288.9 VBB30808.1 - 0.092 13.0 5.1 0.91 9.8 0.1 3.7 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 UPF0547 PF10571.9 VBB30808.1 - 0.27 11.4 5.3 0.94 9.6 5.3 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 VBB30808.1 - 2 8.5 9.1 9.8 6.2 9.1 2.3 1 0 0 1 1 1 0 zinc-ribbons PI3Ka PF00613.20 VBB30809.1 - 1.9e-49 167.6 2.5 3.2e-49 166.8 2.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 VBB30809.1 - 6.6e-46 157.1 0.0 4e-32 112.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 VBB30809.1 - 7.2e-25 87.5 0.0 1.4e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 NuA4 PF09340.10 VBB30809.1 - 2e-22 78.8 0.0 4.5e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF1981 PF09324.10 VBB30810.1 - 1.5e-06 27.9 3.5 5.8e-06 26.1 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 VBB30810.1 - 0.0014 18.5 0.5 0.0014 18.5 0.5 3.4 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SNAPc_SNAP43 PF09808.9 VBB30810.1 - 0.18 11.7 4.5 0.12 12.3 0.7 2.4 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 zinc_ribbon_12 PF11331.8 VBB30810.1 - 0.41 10.5 3.6 3.8 7.4 0.9 2.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain E7 PF00527.18 VBB30810.1 - 7 6.9 9.9 4.2 7.6 0.4 3.6 3 0 0 3 3 3 0 E7 protein, Early protein Ank_2 PF12796.7 VBB30811.1 - 1.6e-111 365.1 32.4 5e-17 62.3 0.1 12.3 2 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB30811.1 - 2.1e-95 311.9 40.8 8.9e-13 48.5 0.0 17.5 8 5 9 18 18 18 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB30811.1 - 5.6e-76 241.4 42.8 3.9e-05 23.7 0.0 24.2 23 1 1 24 24 24 19 Ankyrin repeat Ank_5 PF13857.6 VBB30811.1 - 2e-72 238.3 45.7 6.2e-10 39.1 0.1 18.9 10 5 9 19 19 19 14 Ankyrin repeats (many copies) Ank PF00023.30 VBB30811.1 - 3.8e-65 213.7 55.1 4.8e-06 26.8 0.0 23.6 23 1 0 23 23 23 15 Ankyrin repeat GATase_7 PF13537.6 VBB30811.1 - 0.0034 17.3 0.0 32 4.4 0.0 4.6 3 2 1 4 4 4 0 Glutamine amidotransferase domain DUF3718 PF12514.8 VBB30811.1 - 0.13 12.4 0.5 15 5.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) Sushi PF00084.20 VBB30812.1 - 4.2e-10 40.1 0.1 0.00011 22.8 0.0 2.2 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) PP2C_2 PF13672.6 VBB30813.1 - 6e-11 42.4 0.1 1.2e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 VBB30813.1 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF4071 PF13281.6 VBB30814.1 - 5.8e-118 394.1 2.2 1e-117 393.4 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 VBB30814.1 - 1.9e-60 204.4 0.0 3.7e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30814.1 - 6.7e-45 153.4 0.0 1.3e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB30814.1 - 0.00036 19.4 0.0 0.004 16.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Tmemb_cc2 PF10267.9 VBB30814.1 - 0.0024 17.1 0.6 0.005 16.0 0.6 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein SAM_2 PF07647.17 VBB30814.1 - 0.047 13.8 0.1 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CENP-F_leu_zip PF10473.9 VBB30814.1 - 0.42 10.6 4.8 1.3 9.1 4.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DEAD PF00270.29 VBB30816.1 - 3.4e-46 157.2 0.0 5.5e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB30816.1 - 2.4e-31 108.3 0.0 2.1e-30 105.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB30816.1 - 0.024 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CUB PF00431.20 VBB30817.1 - 2e-41 140.8 0.4 6.5e-14 52.2 0.0 4.4 4 0 0 4 4 4 4 CUB domain CUB_2 PF02408.20 VBB30817.1 - 0.026 14.3 3.4 0.89 9.3 0.0 3.9 4 0 0 4 4 4 0 CUB-like domain Rdx PF10262.9 VBB30819.1 - 1.6e-13 50.7 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Rdx family Mo25 PF08569.11 VBB30820.1 - 1e-140 468.8 14.7 1.1e-140 468.6 14.7 1.0 1 0 0 1 1 1 1 Mo25-like DUF2951 PF11166.8 VBB30820.1 - 0.63 10.3 3.9 6.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Occludin_ELL PF07303.13 VBB30820.1 - 4.6 8.0 7.8 7 7.4 0.1 3.3 4 1 0 4 4 4 0 Occludin homology domain RRM_1 PF00076.22 VBB30821.1 - 2.9e-58 193.6 3.4 6.1e-22 77.2 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB30821.1 - 2.3e-06 27.2 0.0 0.28 10.8 0.0 4.1 3 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB30821.1 - 3.6e-06 26.7 0.0 0.0004 20.2 0.0 2.9 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 VBB30821.1 - 1.4e-05 25.2 1.1 0.41 10.8 0.0 4.7 4 2 0 4 4 4 1 RNA recognition motif PHM7_cyt PF14703.6 VBB30821.1 - 2.3e-05 24.7 0.1 0.084 13.1 0.0 3.4 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 VBB30821.1 - 0.0012 18.9 0.3 0.052 13.6 0.0 2.8 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 VBB30821.1 - 0.0026 17.7 0.3 1.1 9.2 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 VBB30821.1 - 0.0036 17.1 0.2 0.069 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 VBB30821.1 - 0.0053 16.8 0.2 0.58 10.2 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Calcipressin PF04847.12 VBB30821.1 - 0.024 14.4 0.3 0.084 12.6 0.0 1.9 2 0 0 2 2 2 0 Calcipressin RL PF17797.1 VBB30821.1 - 0.13 12.2 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 RL domain SET_assoc PF11767.8 VBB30821.1 - 0.14 11.9 0.4 47 3.7 0.0 3.1 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated DUF1179 PF06678.11 VBB30822.1 - 0.015 15.3 5.5 1.1 9.3 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1179) SIT PF15330.6 VBB30822.1 - 0.19 12.1 2.6 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT AAA PF00004.29 VBB30823.1 - 4.3e-44 150.2 0.1 1e-43 148.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 VBB30823.1 - 6.4e-11 42.0 0.2 1.8e-10 40.6 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 VBB30823.1 - 9.8e-10 38.1 0.0 2.6e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 VBB30823.1 - 4.5e-08 33.4 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 VBB30823.1 - 5.8e-08 32.8 0.0 1.5e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB30823.1 - 4.1e-05 24.0 0.2 0.0046 17.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 VBB30823.1 - 0.00018 21.3 0.0 0.00055 19.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 VBB30823.1 - 0.00022 21.6 0.2 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 VBB30823.1 - 0.00026 20.2 0.0 0.00064 19.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 VBB30823.1 - 0.00091 19.3 0.0 0.0074 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 VBB30823.1 - 0.0012 18.3 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 VBB30823.1 - 0.0014 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 VBB30823.1 - 0.0018 18.6 1.2 0.18 12.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 VBB30823.1 - 0.0031 17.7 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 VBB30823.1 - 0.0035 17.3 0.1 0.18 11.7 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_18 PF13238.6 VBB30823.1 - 0.0073 16.8 0.0 0.0073 16.8 0.0 2.5 3 1 0 3 3 1 1 AAA domain NACHT PF05729.12 VBB30823.1 - 0.028 14.4 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 VBB30823.1 - 0.028 14.2 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 VBB30823.1 - 0.036 14.1 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 VBB30823.1 - 0.049 13.5 0.0 0.34 10.8 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 VBB30823.1 - 0.055 13.0 0.7 0.18 11.4 0.2 1.9 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 VBB30823.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 VBB30823.1 - 0.068 13.0 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 VBB30823.1 - 0.078 13.4 0.2 0.58 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 VBB30823.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 VBB30823.1 - 0.12 12.1 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 VBB30823.1 - 0.13 11.6 0.2 4.3 6.7 0.0 2.6 3 0 0 3 3 2 0 Bacterial TniB protein SWIRM-assoc_1 PF16495.5 VBB30823.1 - 1.8 8.6 5.5 4.7 7.3 5.5 1.6 1 0 0 1 1 1 0 SWIRM-associated region 1 AAA_11 PF13086.6 VBB30823.1 - 4.1 7.1 7.2 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF1279 PF06916.13 VBB30824.1 - 3.2e-19 69.3 2.8 9e-19 67.8 2.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Acyltransferase PF01553.21 VBB30824.1 - 4.7e-06 26.3 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Coa1 PF08695.10 VBB30824.1 - 7.1e-06 25.8 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DAGAT PF03982.13 VBB30824.1 - 0.0022 16.9 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PIG-P PF08510.12 VBB30824.1 - 0.0054 16.6 1.1 0.0054 16.6 1.1 2.4 2 0 0 2 2 2 1 PIG-P TEP1_N PF05386.11 VBB30824.1 - 0.049 13.2 0.6 0.12 12.0 0.6 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain CN_hydrolase PF00795.22 VBB30826.1 - 3.6e-59 200.2 0.0 5.1e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glycos_transf_2 PF00535.26 VBB30826.1 - 7.9e-30 103.9 0.0 1.7e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB30826.1 - 4.6e-23 81.9 0.5 8.2e-23 81.0 0.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain HIT PF01230.23 VBB30826.1 - 2.5e-19 69.8 0.1 6.2e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 HIT domain Glyco_tranf_2_2 PF10111.9 VBB30826.1 - 3.7e-08 33.2 0.0 9.1e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 VBB30826.1 - 9.3e-06 25.2 0.2 2.1e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DcpS_C PF11969.8 VBB30826.1 - 4.5e-05 23.9 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 VBB30826.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain ACI44 PF15270.6 VBB30826.1 - 0.15 12.3 0.4 35 4.7 0.2 3.1 3 0 0 3 3 3 0 Metallo-carboxypeptidase inhibitor HSP20 PF00011.21 VBB30827.1 - 4.6e-11 42.8 0.4 9.3e-11 41.8 0.4 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB30827.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF2889 PF11136.8 VBB30827.1 - 0.018 15.4 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) RFC1 PF08519.12 VBB30828.1 - 6.1e-49 166.2 0.0 4e-48 163.6 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 VBB30828.1 - 4.3e-14 53.1 0.0 1.4e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 VBB30828.1 - 9e-05 23.0 0.1 0.00061 20.3 0.1 2.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 VBB30828.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB30828.1 - 0.0015 18.8 1.3 0.16 12.2 1.3 2.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 VBB30828.1 - 0.0025 17.6 2.0 0.11 12.3 0.2 2.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 VBB30828.1 - 0.003 17.6 0.0 0.0074 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB30828.1 - 0.0088 16.4 0.0 0.042 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 VBB30828.1 - 0.013 15.6 0.0 0.041 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 VBB30828.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 VBB30828.1 - 0.016 15.1 0.5 0.084 12.8 0.0 2.4 1 1 1 2 2 2 0 NTPase DNA_pol3_delta PF06144.13 VBB30828.1 - 0.017 14.9 0.1 0.049 13.4 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.15 VBB30828.1 - 0.024 14.7 4.3 0.16 12.0 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 VBB30828.1 - 0.04 14.1 0.0 0.17 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB30828.1 - 0.047 14.1 0.1 0.36 11.2 0.1 2.5 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 VBB30828.1 - 0.053 13.4 0.1 0.32 10.9 0.0 2.4 2 1 0 2 2 1 0 NACHT domain AAA_25 PF13481.6 VBB30828.1 - 0.057 13.0 0.1 0.18 11.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 VBB30828.1 - 0.086 13.2 0.0 0.43 11.0 0.0 2.3 1 0 0 1 1 1 0 AAA C-terminal domain AAA_19 PF13245.6 VBB30828.1 - 0.11 12.9 1.0 0.77 10.1 1.0 2.3 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 VBB30828.1 - 0.3 11.0 6.5 0.076 12.9 0.4 2.7 2 1 0 2 2 1 0 Rad17 P-loop domain SH2 PF00017.24 VBB30829.1 - 1.2e-11 44.6 0.2 1.9e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 VBB30829.1 - 3.6e-07 30.4 1.0 6.2e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 SOCS box Pkinase PF00069.25 VBB30830.1 - 4.6e-28 98.3 0.2 7.9e-28 97.5 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB30830.1 - 1e-12 47.9 0.1 1.4e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FERM_C PF09380.10 VBB30831.1 - 6.7e-22 77.7 1.5 1.4e-21 76.7 1.5 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 VBB30831.1 - 2e-15 56.5 0.1 4.6e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 VBB30831.1 - 2.6e-14 53.6 0.0 6.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 VBB30831.1 - 1.1e-09 38.2 5.1 1.1e-09 38.2 5.1 2.7 2 0 0 2 2 2 1 FERM adjacent (FA) HYLS1_C PF15311.6 VBB30832.1 - 1.3e-08 35.5 0.0 2.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus ICAT PF06384.11 VBB30832.1 - 0.056 13.7 1.7 0.21 11.8 0.5 2.2 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT DUF4854 PF16146.5 VBB30832.1 - 0.4 11.0 3.3 4.3 7.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) PMI_typeI PF01238.21 VBB30833.1 - 2e-87 293.8 0.0 2.4e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Lipase_GDSL PF00657.22 VBB30833.1 - 0.048 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase FYVE PF01363.21 VBB30834.1 - 6.8e-19 67.8 13.1 6.8e-19 67.8 13.1 2.6 3 0 0 3 3 3 1 FYVE zinc finger Tropomyosin PF00261.20 VBB30834.1 - 0.00075 18.9 12.2 0.00075 18.9 12.2 9.3 1 1 7 9 9 9 1 Tropomyosin zf-C2H2_4 PF13894.6 VBB30834.1 - 0.046 14.6 1.1 0.046 14.6 1.1 3.7 2 1 1 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 VBB30834.1 - 0.11 12.8 9.2 0.18 12.0 6.2 3.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 VBB30834.1 - 1.5 8.7 6.4 2.5 8.0 0.3 3.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-RING_2 PF13639.6 VBB30834.1 - 4.2 7.8 16.4 44 4.5 0.1 2.8 2 0 0 2 2 2 0 Ring finger domain C1_4 PF07975.12 VBB30834.1 - 4.4 7.6 10.2 35 4.7 6.8 3.6 2 1 0 2 2 2 0 TFIIH C1-like domain T2SSF PF00482.23 VBB30834.1 - 8.6 6.3 9.9 4.3 7.3 0.1 4.7 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F Beta-lactamase PF00144.24 VBB30837.1 - 3.1e-34 118.7 0.0 8.2e-34 117.3 0.0 1.5 1 1 1 2 2 2 1 Beta-lactamase Beta-lactamase2 PF13354.6 VBB30837.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 VBB30837.1 - 0.03 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase NifU_N PF01592.16 VBB30838.1 - 2.3e-56 189.4 0.1 2.7e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Beta-lactamase PF00144.24 VBB30839.1 - 3.3e-20 72.6 0.0 4.4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase WHEP-TRS PF00458.20 VBB30839.1 - 0.017 15.3 0.2 0.034 14.3 0.2 1.5 1 0 0 1 1 1 0 WHEP-TRS domain Methyltransf_32 PF13679.6 VBB30839.1 - 0.068 13.1 0.2 0.17 11.8 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain EF-hand_13 PF17958.1 VBB30840.1 - 3.6e-27 94.0 0.6 6.7e-26 89.9 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 VBB30840.1 - 1.6e-14 54.1 1.6 1.9e-13 50.6 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB30840.1 - 4.3e-08 32.5 0.7 0.00077 19.2 0.0 4.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 VBB30840.1 - 5.6e-08 31.8 3.0 7.3e-05 22.0 0.4 4.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 VBB30840.1 - 1.3e-07 30.8 0.7 1e-06 27.9 0.1 3.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 VBB30840.1 - 0.014 15.2 2.6 0.04 13.8 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain pair FANCI_S1 PF14675.6 VBB30840.1 - 0.087 12.4 0.4 5 6.6 0.1 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 NUT PF12881.7 VBB30840.1 - 0.15 10.5 0.0 0.33 9.3 0.0 1.5 2 0 0 2 2 2 0 NUT protein SPARC_Ca_bdg PF10591.9 VBB30840.1 - 1.2 9.5 6.7 26 5.2 0.0 4.1 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region VPS28 PF03997.12 VBB30842.1 - 9.1e-43 146.1 0.2 1.3e-42 145.7 0.2 1.2 1 0 0 1 1 1 1 VPS28 protein Ribosomal_S27e PF01667.17 VBB30842.1 - 7.7e-26 89.6 6.8 7.7e-26 89.6 6.8 2.1 2 0 0 2 2 2 1 Ribosomal protein S27 COX4 PF02936.14 VBB30843.1 - 2.5e-30 105.3 0.1 3.3e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV FlaF PF07309.11 VBB30846.1 - 0.097 12.7 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Flagellar protein FlaF SRCR PF00530.18 VBB30847.1 - 8.6e-33 112.8 1.3 5.6e-17 62.1 0.0 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 VBB30847.1 - 4.9e-13 49.2 69.7 2.7e-06 27.3 1.3 7.2 5 2 0 6 6 6 4 Right handed beta helix region SRCR_2 PF15494.6 VBB30847.1 - 2.4e-07 31.2 6.6 1.7e-05 25.3 0.7 3.3 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 VBB30847.1 - 0.019 15.5 2.3 0.53 10.8 0.0 2.8 3 0 0 3 3 3 0 Hepsin, SRCR domain Gal-bind_lectin PF00337.22 VBB30848.1 - 5.6e-55 184.5 0.0 1.8e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin EHN PF06441.12 VBB30849.1 - 1.6e-30 105.7 0.0 3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 VBB30849.1 - 5.7e-07 29.4 0.1 8.2e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold MPC PF03650.13 VBB30850.1 - 3.1e-38 130.3 0.0 5.1e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MPP6 PF10175.9 VBB30850.1 - 2.4e-12 47.5 11.5 5.6e-12 46.3 11.5 1.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 MtN3_slv PF03083.16 VBB30850.1 - 0.03 14.4 0.3 0.047 13.7 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange NTP_transferase PF00483.23 VBB30851.1 - 5e-25 88.5 0.0 6.7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 VBB30851.1 - 2.1e-07 30.4 5.1 5.8e-05 22.6 0.0 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 VBB30851.1 - 4.5e-06 27.1 0.0 7.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain PB1 PF00564.24 VBB30852.1 - 3e-14 52.7 1.2 4.9e-14 52.0 1.2 1.3 1 0 0 1 1 1 1 PB1 domain SL4P PF17618.2 VBB30852.1 - 0.072 13.1 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Ion_trans PF00520.31 VBB30853.1 - 4.8e-09 35.8 10.3 8.6e-08 31.7 1.9 2.1 1 1 1 2 2 2 2 Ion transport protein DUF1218 PF06749.12 VBB30853.1 - 0.0048 17.4 0.2 0.0083 16.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1218) zf-C3HC4_3 PF13920.6 VBB30856.1 - 1.5e-14 53.6 9.9 1.5e-14 53.6 9.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB30856.1 - 1.6e-06 27.8 10.8 1.6e-06 27.8 10.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 VBB30856.1 - 5.8e-05 23.3 12.5 5.8e-05 23.3 12.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB30856.1 - 0.013 15.4 11.5 0.013 15.4 11.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB30856.1 - 0.02 14.9 10.6 0.02 14.9 10.6 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 VBB30856.1 - 0.11 12.3 4.7 0.42 10.4 2.4 2.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 VBB30856.1 - 1.5 8.9 8.8 27 4.9 5.1 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Histone_H2A_C PF16211.5 VBB30857.1 - 7.2e-11 41.6 0.0 1.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 VBB30857.1 - 1.2e-06 28.9 0.1 2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 VBB30857.1 - 0.048 13.7 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_7N PF13733.6 VBB30858.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.6 1 1 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Glyco_transf_7N PF13733.6 VBB30859.1 - 7.6e-41 138.9 0.0 1.5e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 VBB30859.1 - 3.1e-28 97.2 0.4 6.1e-28 96.3 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CBM_48 PF02922.18 VBB30860.1 - 4.4e-15 55.8 0.1 1.1e-14 54.5 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 VBB30860.1 - 5.1e-13 49.3 0.8 5e-11 42.8 0.8 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Cellulase PF00150.18 VBB30860.1 - 0.0049 16.3 0.3 0.028 13.9 0.0 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.6 VBB30860.1 - 0.1 11.7 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 VBB30860.1 - 0.18 10.8 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V PBD PF00786.28 VBB30861.1 - 0.0044 17.3 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain DUF167 PF02594.16 VBB30862.1 - 1.2e-18 67.0 0.1 1.2e-18 67.0 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 Med28 PF11594.8 VBB30863.1 - 5.5e-20 71.8 2.1 1.4e-19 70.5 2.1 1.7 1 0 0 1 1 1 1 Mediator complex subunit 28 V-ATPase_G_2 PF16999.5 VBB30863.1 - 0.0013 19.1 1.4 0.0035 17.8 1.4 1.6 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Perilipin PF03036.16 VBB30863.1 - 0.007 15.4 8.3 0.059 12.4 8.3 1.9 1 1 0 1 1 1 1 Perilipin family YtxH PF12732.7 VBB30863.1 - 0.011 16.3 6.7 0.012 16.1 0.4 2.8 3 1 0 3 3 3 0 YtxH-like protein TarH PF02203.15 VBB30863.1 - 0.021 14.8 0.5 0.041 13.8 0.5 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF4665 PF15679.5 VBB30863.1 - 0.061 14.0 0.4 0.21 12.2 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) PTPA PF03095.15 VBB30863.1 - 0.22 11.0 2.4 4.1 6.8 0.2 2.3 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein PMC2NT PF08066.12 VBB30863.1 - 0.52 11.0 4.9 7 7.4 0.2 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain DUF883 PF05957.13 VBB30863.1 - 2.1 9.0 7.9 1.6 9.4 1.7 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4351 PF14261.6 VBB30863.1 - 3.2 7.9 6.7 3.4 7.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) CLTH PF10607.9 VBB30864.1 - 1.1e-22 80.6 0.3 1.9e-22 79.7 0.3 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 VBB30864.1 - 0.00081 19.3 0.1 0.0032 17.4 0.0 2.0 2 0 0 2 2 2 1 LisH Pro_isomerase PF00160.21 VBB30865.1 - 1.5e-52 178.0 0.2 3e-52 177.1 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FPN1 PF06963.12 VBB30866.1 - 5.9e-100 334.9 14.6 9.1e-100 334.2 14.6 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) WD40 PF00400.32 VBB30866.1 - 1.1e-35 121.0 21.9 4.6e-08 33.6 0.6 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat HA2 PF04408.23 VBB30867.1 - 8e-20 71.1 0.0 8e-20 71.1 0.0 2.8 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 VBB30867.1 - 5.7e-16 58.7 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 VBB30867.1 - 2.8e-13 50.2 0.3 1.5e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 VBB30867.1 - 2.7e-05 24.4 3.0 3.3e-05 24.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain DEAD PF00270.29 VBB30867.1 - 3.6e-05 23.6 0.0 0.00021 21.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 VBB30867.1 - 0.00021 21.1 0.0 0.00063 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 VBB30867.1 - 0.00097 18.3 0.0 0.0037 16.4 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Reprolysin PF01421.19 VBB30867.1 - 0.0038 17.2 0.1 0.0096 15.8 0.0 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease AAA_19 PF13245.6 VBB30867.1 - 0.007 16.7 1.6 0.013 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 VBB30867.1 - 0.0083 16.1 0.3 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Flavivirus DEAD domain NACHT PF05729.12 VBB30867.1 - 0.046 13.6 2.1 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 VBB30867.1 - 1.5 9.4 4.5 16 6.0 0.0 3.4 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.6 VBB30867.1 - 1.9 9.0 0.0 1.9 9.0 0.0 3.2 2 1 0 2 2 1 0 AAA domain Atg8 PF02991.16 VBB30868.1 - 5.7e-49 164.6 0.7 6.7e-49 164.4 0.2 1.3 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 VBB30868.1 - 1.4e-05 25.4 0.0 1.9e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 zf-RING_2 PF13639.6 VBB30869.1 - 0.00057 20.2 5.6 0.0011 19.2 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 VBB30869.1 - 0.038 13.9 4.0 0.074 12.9 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB30869.1 - 0.049 13.9 7.1 0.14 12.4 7.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 VBB30869.1 - 0.66 9.9 5.9 1.4 8.8 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YfiO PF13525.6 VBB30870.1 - 0.01 15.6 1.1 0.04 13.6 0.1 2.3 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_8 PF13181.6 VBB30870.1 - 0.019 15.2 5.1 0.14 12.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 VBB30870.1 - 0.022 15.4 2.1 5.6 7.8 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB30870.1 - 0.054 13.7 0.7 0.16 12.2 0.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 VBB30870.1 - 0.057 13.6 8.8 5.3 7.4 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FKBP_C PF00254.28 VBB30870.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 VBB30870.1 - 0.3 11.0 7.8 0.15 11.9 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PaREP1 PF05942.11 VBB30870.1 - 0.97 9.4 4.0 4.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Hormone_recep PF00104.30 VBB30872.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Neur_chan_memb PF02932.16 VBB30873.1 - 0.00022 21.4 0.0 0.00022 21.3 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_phi PF04931.13 VBB30874.1 - 9.3e-42 143.1 43.7 6e-31 107.3 21.1 4.2 4 1 1 5 5 5 3 DNA polymerase phi SDA1 PF05285.12 VBB30874.1 - 0.013 14.9 10.3 0.023 14.1 10.3 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 VBB30874.1 - 0.19 11.0 11.3 0.45 9.8 11.3 1.5 1 0 0 1 1 1 0 BUD22 Neur_chan_memb PF02932.16 VBB30875.1 - 2.7e-62 211.0 10.1 4.5e-35 121.8 1.7 3.1 3 0 0 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 VBB30875.1 - 3e-37 128.2 0.1 9.9e-36 123.2 0.0 2.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain DUF21 PF01595.20 VBB30875.1 - 0.59 9.8 9.0 9.3 5.9 0.1 3.9 3 1 0 4 4 4 0 Cyclin M transmembrane N-terminal domain CLASP_N PF12348.8 VBB30876.1 - 1.5e-30 106.5 3.3 1.5e-30 106.5 3.3 2.8 4 1 0 4 4 4 1 CLASP N terminal HEAT PF02985.22 VBB30876.1 - 0.00042 20.3 2.5 3.2 8.3 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat TAN PF11640.8 VBB30876.1 - 0.04 14.1 0.6 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF3385 PF11865.8 VBB30876.1 - 0.83 9.6 7.3 1.9 8.4 0.1 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Pkinase_Tyr PF07714.17 VBB30877.1 - 1.1e-64 218.2 1.6 2.1e-64 217.3 1.6 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB30877.1 - 1.9e-38 132.4 3.2 3e-38 131.7 3.2 1.3 1 0 0 1 1 1 1 Protein kinase domain TTR-52 PF01060.23 VBB30877.1 - 3.7e-08 34.0 0.0 8.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Transthyretin-like family SH2 PF00017.24 VBB30877.1 - 0.0018 18.3 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain YrbL-PhoP_reg PF10707.9 VBB30877.1 - 0.012 15.2 0.3 0.028 14.0 0.3 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 VBB30877.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0542 PF15086.6 VBB30877.1 - 0.46 10.4 2.1 17 5.4 1.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 SNARE_assoc PF09335.11 VBB30879.1 - 1.7e-17 64.0 6.4 1.7e-17 64.0 6.4 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein DPM3 PF08285.11 VBB30879.1 - 1.6 9.0 0.0 1.6 9.0 0.0 2.9 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) BING4CT PF08149.11 VBB30880.1 - 6.9e-36 121.9 0.0 2.3e-35 120.2 0.0 2.0 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.32 VBB30880.1 - 4.2e-05 24.2 0.1 0.32 11.9 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB30880.1 - 0.003 17.8 0.0 3.7 7.9 0.0 4.2 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB30880.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 VBB30880.1 - 0.014 14.1 0.0 0.03 13.0 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 EF-hand_1 PF00036.32 VBB30882.1 - 3.6e-35 116.9 16.2 3.9e-09 35.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB30882.1 - 1.2e-29 102.5 7.7 7.7e-16 58.3 2.3 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB30882.1 - 6.7e-27 91.1 9.5 3.5e-08 32.7 0.2 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 VBB30882.1 - 1.8e-23 82.1 15.5 2.3e-12 46.5 1.1 4.5 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB30882.1 - 1.3e-13 49.7 15.8 5.8e-06 25.6 0.1 5.0 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 VBB30882.1 - 6.6e-10 39.2 0.2 0.00014 22.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 VBB30882.1 - 5.4e-06 26.7 1.0 0.042 14.2 0.4 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 VBB30882.1 - 1.1e-05 25.4 3.3 0.13 12.2 0.3 3.0 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_4 PF12763.7 VBB30882.1 - 3.8e-05 23.6 4.8 0.17 11.8 0.2 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 VBB30882.1 - 0.0039 17.4 4.7 0.12 12.6 0.2 2.7 1 1 1 2 2 2 2 p25-alpha DUF3349 PF11829.8 VBB30882.1 - 0.0086 16.8 0.1 0.036 14.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) UPF0154 PF03672.13 VBB30882.1 - 0.031 14.3 0.3 0.38 10.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 VBB30882.1 - 0.095 12.6 5.9 22 4.9 0.1 3.8 1 1 3 4 4 4 0 Caleosin related protein Myb_DNA-binding PF00249.31 VBB30882.1 - 0.15 12.3 0.4 12 6.2 0.0 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain Dockerin_1 PF00404.18 VBB30882.1 - 0.27 11.5 1.4 2.8 8.2 0.2 3.1 2 2 0 2 2 2 0 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 VBB30882.1 - 2.1 8.7 4.7 1.9 8.9 0.1 2.6 2 1 0 2 2 2 0 RNA polymerase Rpb4 EF-hand_10 PF14788.6 VBB30882.1 - 3.7 7.5 7.4 1.2 9.1 1.4 2.9 3 0 0 3 3 3 0 EF hand Tetraspanin PF00335.20 VBB30883.1 - 1.4e-33 116.5 2.8 2.5e-33 115.7 2.8 1.4 1 0 0 1 1 1 1 Tetraspanin family WD40 PF00400.32 VBB30883.1 - 4.7e-23 81.0 15.4 0.00022 22.0 1.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 VBB30883.1 - 8.2e-11 42.3 1.4 1.8e-10 41.2 1.4 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Cir_N PF10197.9 VBB30883.1 - 3.1e-09 36.9 6.6 3.1e-09 36.9 6.6 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 VBB30883.1 - 0.0018 18.1 0.3 0.0052 16.6 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle YbaJ PF10757.9 VBB30884.1 - 0.094 13.3 0.3 0.17 12.5 0.3 1.4 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ Frizzled PF01534.17 VBB30885.1 - 4.7e-44 150.7 4.5 6.3e-44 150.3 4.5 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region STE3 PF02076.15 VBB30885.1 - 0.0063 15.8 0.7 0.0089 15.3 0.5 1.3 1 1 0 1 1 1 1 Pheromone A receptor Rootletin PF15035.6 VBB30886.1 - 5e-34 118.0 28.1 5e-34 118.0 28.1 9.0 4 3 3 7 7 4 3 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 VBB30886.1 - 1.7e-05 25.3 1.1 1.7e-05 25.3 1.1 17.1 8 5 9 18 18 16 3 SlyX Spc7 PF08317.11 VBB30886.1 - 1.8e-05 23.8 193.0 0.00092 18.2 13.3 11.2 2 2 9 12 12 12 7 Spc7 kinetochore protein Filament PF00038.21 VBB30886.1 - 3.7e-05 23.5 194.1 0.011 15.4 41.4 8.0 1 1 7 8 8 8 6 Intermediate filament protein ATG16 PF08614.11 VBB30886.1 - 0.00019 21.7 10.5 0.00019 21.7 10.5 11.3 2 2 7 9 9 7 1 Autophagy protein 16 (ATG16) BST2 PF16716.5 VBB30886.1 - 0.00079 20.0 8.8 0.00079 20.0 8.8 15.1 7 4 7 15 15 14 2 Bone marrow stromal antigen 2 GAS PF13851.6 VBB30886.1 - 0.0013 18.2 36.7 0.0024 17.3 12.6 11.1 4 2 8 12 12 10 5 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 VBB30886.1 - 0.0026 17.2 138.0 0.011 15.2 12.8 9.9 2 2 7 9 9 9 6 Domain of unknown function (DUF4407) GIT_CC PF16559.5 VBB30886.1 - 0.01 15.7 0.5 0.01 15.7 0.5 11.8 12 2 0 12 12 12 0 GIT coiled-coil Rho guanine nucleotide exchange factor FliJ PF02050.16 VBB30886.1 - 0.011 15.9 4.7 0.011 15.9 4.7 13.4 6 4 8 14 14 12 0 Flagellar FliJ protein TolA_bind_tri PF16331.5 VBB30886.1 - 0.033 14.3 0.7 0.033 14.3 0.7 14.3 8 5 6 14 14 14 0 TolA binding protein trimerisation ADIP PF11559.8 VBB30886.1 - 0.11 12.5 196.7 0.012 15.7 15.2 13.5 4 1 8 13 13 13 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 VBB30886.1 - 0.15 12.1 114.7 0.014 15.4 3.0 14.1 6 4 10 16 16 16 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 VBB30886.1 - 0.59 10.5 178.3 0.062 13.7 16.0 9.3 2 2 6 8 8 7 0 Fez1 HMMR_N PF15905.5 VBB30886.1 - 1.1 8.6 187.9 0.035 13.6 26.6 8.2 2 1 6 8 8 7 0 Hyaluronan mediated motility receptor N-terminal Kelch_1 PF01344.25 VBB30887.1 - 1.3e-37 127.1 3.9 6.8e-08 32.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 VBB30887.1 - 1.3e-37 127.2 7.6 6.1e-06 26.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 VBB30887.1 - 4.1e-37 125.8 5.0 2.8e-09 37.0 0.0 7.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 VBB30887.1 - 5.1e-35 118.6 1.8 8.8e-06 25.8 0.0 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.6 VBB30887.1 - 2.1e-34 117.3 3.2 8.1e-06 25.8 0.0 7.1 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 VBB30887.1 - 2.9e-31 106.2 12.8 4.1e-05 23.4 0.0 6.8 6 1 0 6 6 6 6 Kelch motif CPBP PF02517.16 VBB30888.1 - 1.5e-09 38.1 1.8 1.5e-08 34.9 0.7 2.7 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Bestrophin PF01062.21 VBB30889.1 - 7.1e-76 255.4 0.5 8e-76 255.2 0.5 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Hexapep PF00132.24 VBB30891.1 - 3.3e-08 32.9 23.5 0.0011 18.6 4.1 4.2 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 VBB30891.1 - 0.088 12.6 18.3 4.9 7.0 1.3 4.4 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase eRF1_2 PF03464.15 VBB30893.1 - 3.6e-47 160.0 0.1 5.9e-47 159.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 VBB30893.1 - 1.2e-34 119.2 0.3 3.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 VBB30893.1 - 1.2e-18 67.3 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 VBB30893.1 - 1.8e-09 38.0 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 VBB30893.1 - 7.8e-09 35.9 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Reprolysin PF01421.19 VBB30894.1 - 4.8e-45 153.9 0.0 4.8e-45 153.9 0.0 1.9 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 VBB30894.1 - 1.9e-22 79.9 5.2 1.9e-22 79.9 5.2 3.7 3 1 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.23 VBB30894.1 - 1.9e-19 70.2 27.7 1.9e-19 70.2 27.7 4.2 5 0 0 5 5 5 1 Disintegrin Reprolysin_5 PF13688.6 VBB30894.1 - 1.1e-17 64.8 1.3 1.9e-17 64.1 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 VBB30894.1 - 2.4e-09 37.4 0.2 4.6e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 VBB30894.1 - 6.7e-09 35.7 0.1 1.2e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 VBB30894.1 - 2.9e-08 34.3 0.1 6.4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 VBB30894.1 - 0.0028 18.0 12.6 0.0028 18.0 12.6 4.9 5 0 0 5 5 5 1 EGF-like domain NECFESHC PF16621.5 VBB30894.1 - 1.7 8.7 5.1 0.58 10.2 0.2 2.3 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Integrin_alpha2 PF08441.12 VBB30896.1 - 1.2e-41 143.1 0.2 1.5e-41 142.8 0.2 1.1 1 0 0 1 1 1 1 Integrin alpha Integrin_alpha PF00357.20 VBB30896.1 - 2.1e-05 24.1 0.4 6.7e-05 22.6 0.4 1.9 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region DUF2207 PF09972.9 VBB30896.1 - 0.055 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LRR19-TM PF15176.6 VBB30896.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Pox_EPC_I2-L1 PF12575.8 VBB30896.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF4381 PF14316.6 VBB30896.1 - 0.15 12.3 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DnaJ PF00226.31 VBB30897.1 - 1.4e-19 70.0 1.3 3.1e-19 68.9 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 VBB30897.1 - 2e-07 31.1 0.5 0.0057 16.8 0.0 3.3 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 VBB30897.1 - 3.3e-07 30.4 2.2 0.011 15.9 0.4 3.7 3 1 0 3 3 3 2 Myb-like DNA-binding domain SMC_N PF02463.19 VBB30897.1 - 0.052 13.0 0.4 0.11 12.0 0.4 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Myb_DNA-bind_4 PF13837.6 VBB30897.1 - 2 8.9 9.7 25 5.3 1.1 3.9 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain EF-hand_1 PF00036.32 VBB30898.1 - 2.3e-14 51.8 7.9 2.7e-05 23.4 0.9 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 VBB30898.1 - 5.4e-13 47.7 6.7 0.00093 19.0 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 VBB30898.1 - 8.6e-13 48.5 7.8 5.8e-06 26.7 0.7 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB30898.1 - 5e-11 41.6 8.5 0.0051 16.2 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 VBB30898.1 - 7.2e-06 25.8 4.8 0.067 13.1 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB30898.1 - 0.00067 19.9 0.9 1.5 9.1 0.1 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PRCC PF10253.9 VBB30898.1 - 0.0018 19.1 1.1 0.0021 18.9 1.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting MAAL_N PF05034.13 VBB30898.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus EF-hand_4 PF12763.7 VBB30898.1 - 0.044 13.7 1.4 0.19 11.7 0.7 2.3 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Terpene_synth_C PF03936.16 VBB30898.1 - 0.063 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain CAP PF00188.26 VBB30899.1 - 1.6e-13 51.6 0.0 2.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rhodanese PF00581.20 VBB30900.1 - 3.7e-07 30.6 0.0 1.2e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain RabGAP-TBC PF00566.18 VBB30900.1 - 0.00046 19.9 0.2 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kelch_6 PF13964.6 VBB30901.1 - 5.9e-06 26.4 0.0 2.3e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 VBB30901.1 - 0.00069 19.6 0.0 0.025 14.6 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 VBB30901.1 - 0.0014 18.6 0.1 0.026 14.5 0.0 2.7 2 0 0 2 2 2 1 Kelch motif BAP PF06639.11 VBB30902.1 - 0.22 11.9 4.3 14 6.1 0.1 3.5 3 0 0 3 3 3 0 Basal layer antifungal peptide (BAP) SRCR PF00530.18 VBB30903.1 - 0.002 18.6 0.1 0.002 18.6 0.1 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain EphA2_TM PF14575.6 VBB30903.1 - 0.051 14.5 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lectin_C PF00059.21 VBB30903.1 - 0.057 14.2 0.3 0.057 14.2 0.3 2.9 2 1 0 2 2 2 0 Lectin C-type domain DUF4957 PF16318.5 VBB30903.1 - 0.057 13.3 2.2 0.089 12.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4957) Adeno_E3_CR2 PF02439.15 VBB30903.1 - 0.22 11.3 0.9 0.49 10.2 0.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ldh_1_C PF02866.18 VBB30904.1 - 8.1e-36 123.5 0.0 1.2e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 VBB30904.1 - 2.4e-35 121.7 0.1 3.8e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PE-PPE PF08237.11 VBB30904.1 - 0.0011 18.6 0.2 0.002 17.7 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain VWA PF00092.28 VBB30905.1 - 3.9e-146 483.1 44.5 2.7e-27 96.1 0.3 9.2 8 2 2 10 10 10 8 von Willebrand factor type A domain VWA_2 PF13519.6 VBB30905.1 - 4.9e-81 268.3 25.1 1.5e-11 44.9 0.1 9.4 9 0 0 9 9 9 8 von Willebrand factor type A domain VWA_3 PF13768.6 VBB30905.1 - 3.1e-22 79.2 17.9 0.00099 19.1 0.1 8.5 8 0 0 8 8 8 7 von Willebrand factor type A domain VWA_CoxE PF05762.14 VBB30905.1 - 2.9e-14 53.0 11.8 0.0021 17.5 0.0 8.1 8 0 0 8 8 8 4 VWA domain containing CoxE-like protein DUF1194 PF06707.11 VBB30905.1 - 3.9e-08 32.8 15.6 0.095 11.9 0.0 7.8 8 0 0 8 8 8 3 Protein of unknown function (DUF1194) CHASE4 PF05228.13 VBB30905.1 - 0.048 13.9 0.2 3 8.1 0.1 3.3 3 0 0 3 3 3 0 CHASE4 domain NOG1 PF06858.14 VBB30905.1 - 0.1 12.4 3.5 8.2 6.3 0.0 4.0 4 0 0 4 4 4 0 Nucleolar GTP-binding protein 1 (NOG1) DUF1654 PF07867.11 VBB30905.1 - 0.15 11.8 0.8 46 3.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) Glyco_transf_92 PF01697.27 VBB30905.1 - 10 5.7 10.2 13 5.4 8.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 92 AAA_2 PF07724.14 VBB30906.1 - 2.1e-40 138.6 0.3 3.1e-40 138.1 0.3 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 VBB30906.1 - 1.5e-13 51.3 0.3 4.1e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 VBB30906.1 - 2.5e-09 37.1 0.1 6.3e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 VBB30906.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 VBB30906.1 - 3.4e-06 26.3 0.0 9.6e-06 24.8 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 VBB30906.1 - 3.6e-06 26.8 0.2 3.8e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 VBB30906.1 - 2.2e-05 24.0 0.3 0.11 11.9 0.1 2.8 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 VBB30906.1 - 0.00014 21.4 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 VBB30906.1 - 0.00025 21.4 0.1 0.001 19.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 VBB30906.1 - 0.00046 20.2 0.0 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB30906.1 - 0.0016 18.9 1.5 0.0075 16.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 VBB30906.1 - 0.0041 16.9 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 VBB30906.1 - 0.0064 16.2 0.3 0.032 14.0 0.1 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 VBB30906.1 - 0.041 14.4 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 VBB30906.1 - 0.062 13.2 0.2 5.8 6.8 0.0 3.0 3 0 0 3 3 3 0 NACHT domain DZR PF12773.7 VBB30906.1 - 0.072 13.1 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon CbiA PF01656.23 VBB30906.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activ_2 PF14532.6 VBB30906.1 - 0.097 12.8 0.0 0.28 11.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain C1_1 PF00130.22 VBB30906.1 - 0.099 12.5 1.3 0.19 11.6 1.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_3 PF07726.11 VBB30906.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 VBB30906.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 VBB30906.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 VBB30906.1 - 0.11 12.5 0.0 1.2 9.0 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 VBB30906.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_8 PF12780.7 VBB30906.1 - 0.13 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 TsaE PF02367.17 VBB30906.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DC_STAMP PF07782.13 VBB30907.1 - 2.8e-40 138.2 2.8 4.5e-40 137.5 0.8 2.3 2 0 0 2 2 2 1 DC-STAMP-like protein DUF5344 PF17279.2 VBB30907.1 - 0.094 13.3 0.4 0.34 11.5 0.4 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Goodbye PF17109.5 VBB30907.1 - 0.21 12.0 1.3 0.33 11.4 0.2 1.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Syntaxin_2 PF14523.6 VBB30907.1 - 1.4 9.3 7.1 0.84 10.0 0.7 2.6 2 0 0 2 2 2 0 Syntaxin-like protein UPF0172 PF03665.13 VBB30908.1 - 1.4e-43 149.2 0.0 1.8e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Ank_2 PF12796.7 VBB30909.1 - 8.5e-19 67.9 0.2 1.3e-13 51.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB30909.1 - 1.6e-18 66.8 1.3 3e-13 50.0 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB30909.1 - 2.6e-17 62.4 0.4 6.5e-06 26.4 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 VBB30909.1 - 1.5e-14 52.6 0.3 2.5e-06 27.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 VBB30909.1 - 4.1e-13 49.3 1.0 2.7e-07 30.7 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SNX17_FERM_C PF18116.1 VBB30911.1 - 9.1e-08 32.1 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain GMP_PDE_delta PF05351.11 VBB30912.1 - 8.6e-41 139.6 0.0 1.4e-40 139.0 0.0 1.3 1 1 0 1 1 1 1 GMP-PDE, delta subunit DUF1690 PF07956.11 VBB30913.1 - 0.00028 21.3 8.3 0.0013 19.2 8.3 1.9 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) VBS PF08913.10 VBB30913.1 - 0.049 14.1 0.5 0.27 11.7 0.2 2.1 2 0 0 2 2 2 0 Vinculin Binding Site CX9C PF16860.5 VBB30913.1 - 0.053 13.5 1.0 0.11 12.5 1.0 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Noelin-1 PF12308.8 VBB30913.1 - 0.088 12.8 3.0 1.8 8.6 0.5 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF2247 PF10004.9 VBB30913.1 - 0.14 11.9 2.6 0.16 11.8 1.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) kleA_kleC PF17383.2 VBB30913.1 - 0.29 11.5 2.6 1.9 8.9 0.0 2.6 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Spc29 PF17082.5 VBB30913.1 - 0.5 10.2 5.7 0.51 10.1 2.6 2.0 1 1 0 2 2 2 0 Spindle Pole Component 29 DivIC PF04977.15 VBB30913.1 - 2.8 7.8 7.8 1.1 9.0 3.7 2.0 1 1 1 2 2 2 0 Septum formation initiator Glyco_transf_64 PF09258.10 VBB30914.1 - 3.4e-74 249.2 0.1 5.4e-74 248.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 VBB30914.1 - 1.1e-14 54.3 0.0 9.8e-13 48.0 0.0 2.9 1 1 0 1 1 1 1 Exostosin family Phage_holin_2_3 PF16080.5 VBB30915.1 - 3 7.7 7.4 2.6 7.9 0.3 2.8 2 1 1 3 3 3 0 Bacteriophage holin family HP1 DUF3256 PF11644.8 VBB30917.1 - 0.0094 15.5 1.6 0.011 15.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3256) Androgen_recep PF02166.16 VBB30917.1 - 0.079 11.8 6.4 0.073 11.9 6.4 1.1 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 VBB30917.1 - 0.089 12.0 11.1 0.095 11.9 11.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MDM10 PF12519.8 VBB30917.1 - 0.1 11.4 5.2 0.12 11.3 5.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Spt20 PF12090.8 VBB30917.1 - 0.11 12.0 16.7 0.13 11.9 16.7 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 VBB30917.1 - 0.27 11.9 8.1 0.28 11.8 8.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 VBB30917.1 - 0.54 10.0 2.6 0.6 9.8 2.6 1.0 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 VBB30917.1 - 1.1 9.1 4.4 1.2 9.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 VBB30917.1 - 1.2 7.9 8.3 1.2 7.8 8.3 1.0 1 0 0 1 1 1 0 Presenilin DUF5345 PF17280.2 VBB30917.1 - 1.7 8.7 6.9 7.5 6.6 4.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Neur_chan_memb PF02932.16 VBB30917.1 - 2.5 8.1 5.3 2.7 8.0 5.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.13 VBB30917.1 - 2.5 6.8 5.2 3 6.6 5.2 1.0 1 0 0 1 1 1 0 Otopetrin CSG2 PF16965.5 VBB30917.1 - 2.8 6.8 4.1 3 6.7 4.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2722 PF10846.8 VBB30917.1 - 3.2 6.6 18.6 3.8 6.3 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YajC PF02699.15 VBB30917.1 - 3.4 7.6 6.9 46 4.0 7.2 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit PID PF00640.23 VBB30918.1 - 5e-20 72.0 0.2 1.6e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 VBB30918.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 VBB30918.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain Ly-6_related PF06579.12 VBB30919.1 - 1.2e-17 64.3 0.0 1.6e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein UPAR_LY6_2 PF16975.5 VBB30919.1 - 0.021 15.0 0.1 0.029 14.6 0.1 1.1 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Myosin_tail_1 PF01576.19 VBB30920.1 - 6.1e-77 259.5 184.5 6.9e-77 259.3 184.5 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 VBB30920.1 - 1.3e-08 34.9 161.6 0.00053 19.7 18.7 8.3 1 1 5 7 7 7 6 Intermediate filament protein DUF745 PF05335.13 VBB30920.1 - 0.0011 18.7 10.6 0.0011 18.7 10.6 7.9 1 1 7 8 8 8 2 Protein of unknown function (DUF745) DUF1664 PF07889.12 VBB30920.1 - 0.0025 17.9 99.8 0.0057 16.7 7.1 9.7 2 2 6 10 10 10 8 Protein of unknown function (DUF1664) FAM184 PF15665.5 VBB30920.1 - 0.0082 16.0 21.8 0.0082 16.0 21.8 7.8 1 1 5 6 6 6 1 Family with sequence similarity 184, A and B TMF_DNA_bd PF12329.8 VBB30920.1 - 0.0099 15.9 5.5 0.0099 15.9 5.5 15.7 2 1 10 15 15 15 1 TATA element modulatory factor 1 DNA binding HisKA_3 PF07730.13 VBB30920.1 - 0.013 16.0 2.8 0.013 16.0 2.8 11.6 7 4 5 12 12 12 0 Histidine kinase GIT_CC PF16559.5 VBB30920.1 - 0.014 15.3 0.3 0.014 15.3 0.3 12.2 5 2 8 13 13 13 0 GIT coiled-coil Rho guanine nucleotide exchange factor ShlB PF03865.13 VBB30920.1 - 1.2 8.5 5.2 0.22 10.9 0.9 1.9 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB DM13 PF10517.9 VBB30921.1 - 8.2e-27 93.8 0.0 4.4e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 Electron transfer DM13 UPF0182 PF03699.13 VBB30921.1 - 0.012 13.8 0.1 0.015 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) HMG_box PF00505.19 VBB30922.1 - 1.4e-24 86.2 1.9 2.5e-24 85.5 1.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB30922.1 - 2.1e-09 37.9 0.7 3.9e-09 37.0 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain Vps52 PF04129.12 VBB30923.1 - 6.5e-99 332.0 12.3 3.7e-79 266.8 7.8 2.0 1 1 1 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 VBB30923.1 - 2.8e-07 29.4 8.0 4.1e-07 28.8 8.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Spc7 PF08317.11 VBB30923.1 - 0.0024 16.8 3.8 0.0024 16.8 3.8 1.9 1 1 1 2 2 2 1 Spc7 kinetochore protein Sec34 PF04136.15 VBB30923.1 - 0.0053 16.6 5.8 0.0093 15.9 5.1 1.8 1 1 1 2 2 2 2 Sec34-like family PIN_9 PF18477.1 VBB30923.1 - 0.076 13.3 0.4 3.7 7.9 0.0 2.9 2 1 0 2 2 2 0 PIN like domain MscS_porin PF12795.7 VBB30923.1 - 0.52 9.8 11.5 0.038 13.5 6.4 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain MukB PF04310.12 VBB30923.1 - 0.99 9.2 4.9 1.2 8.9 2.8 2.0 1 1 1 2 2 2 0 MukB N-terminal Occludin_ELL PF07303.13 VBB30923.1 - 5 7.9 9.5 20 6.0 3.0 3.3 2 1 1 3 3 3 0 Occludin homology domain HIP1_clath_bdg PF16515.5 VBB30923.1 - 5.7 7.6 11.1 0.18 12.4 1.4 2.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CCDC92 PF14916.6 VBB30923.1 - 9.3 6.1 10.5 11 5.9 1.2 3.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function FAD_binding_2 PF00890.24 VBB30924.1 - 5e-124 414.6 4.7 6.3e-124 414.2 4.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 VBB30924.1 - 5.6e-38 129.8 0.9 9.2e-38 129.1 0.9 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 VBB30924.1 - 1.1e-05 24.8 0.2 0.00087 18.6 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 VBB30924.1 - 0.00015 21.1 0.7 0.026 13.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 VBB30924.1 - 0.00041 19.2 0.2 0.0017 17.2 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 VBB30924.1 - 0.0007 19.3 1.2 0.0019 17.8 0.8 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 VBB30924.1 - 0.0015 17.7 4.0 0.15 11.1 3.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 VBB30924.1 - 0.0057 16.0 1.3 0.011 15.0 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 VBB30924.1 - 0.02 14.2 0.2 0.045 13.1 0.2 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 VBB30925.1 - 6.7e-101 338.4 6.5 5.2e-64 216.9 1.1 2.1 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.20 VBB30925.1 - 6e-39 133.0 0.1 8.7e-39 132.4 0.1 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 VBB30925.1 - 3.1e-05 23.4 0.4 0.00068 19.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 VBB30925.1 - 3.1e-05 23.3 0.1 0.0048 16.2 0.1 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 VBB30925.1 - 0.00063 18.6 0.1 0.0013 17.6 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 VBB30925.1 - 0.002 17.5 1.2 0.0036 16.6 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 VBB30925.1 - 0.014 15.0 0.6 0.023 14.3 0.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 VBB30925.1 - 0.087 11.9 2.3 0.22 10.5 1.8 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 VBB30925.1 - 0.13 11.4 5.8 0.049 12.7 2.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 VBB30926.1 - 8.2e-42 143.4 17.9 8.2e-42 143.4 17.9 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily NIF PF03031.18 VBB30926.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase RAM PF15320.6 VBB30928.1 - 1.7e-07 31.7 2.3 2.5e-07 31.2 2.3 1.2 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein Rhomboid PF01694.22 VBB30929.1 - 1.8e-20 73.5 12.1 1.8e-20 73.5 12.1 2.0 1 1 1 2 2 2 1 Rhomboid family tRNA-synt_2d PF01409.20 VBB30930.1 - 7.5e-90 300.7 0.1 1.1e-89 300.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 VBB30930.1 - 8.2e-22 76.7 0.2 1.7e-21 75.7 0.1 1.7 2 0 0 2 2 2 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 VBB30930.1 - 8.2e-17 61.2 0.0 2.2e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 VBB30930.1 - 2.9e-10 40.0 4.1 5.8e-10 39.0 4.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 VBB30930.1 - 3.3e-07 29.9 0.0 7.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 VBB30930.1 - 1.7e-05 24.0 0.9 0.0014 17.8 0.1 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 VBB30930.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3281 PF11685.8 VBB30930.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) SURF2 PF05477.11 VBB30931.1 - 2.9e-17 63.2 0.7 4.7e-17 62.5 0.7 1.3 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Cob_adeno_trans PF01923.18 VBB30932.1 - 0.011 15.8 0.2 6 7.0 0.0 2.7 2 1 0 2 2 2 0 Cobalamin adenosyltransferase PI-PLC-X PF00388.19 VBB30932.1 - 0.025 14.2 0.5 0.19 11.3 0.2 2.5 1 1 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Lig_C PF18330.1 VBB30932.1 - 0.095 12.7 0.7 4.3 7.4 0.1 2.6 2 1 0 2 2 2 0 Ligase Pab1020 C-terminal region DUF3254 PF11630.8 VBB30932.1 - 0.16 12.1 0.3 0.44 10.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) HA2 PF04408.23 VBB30933.1 - 7e-15 55.2 0.0 7e-15 55.2 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 VBB30933.1 - 8.7e-14 51.6 0.0 2.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 VBB30933.1 - 2.2e-10 40.9 2.6 3e-10 40.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 VBB30933.1 - 3.2e-09 36.8 1.4 6.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 VBB30933.1 - 1.8e-05 25.0 0.4 9.4e-05 22.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 VBB30933.1 - 0.0045 16.7 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 VBB30933.1 - 0.0056 17.0 0.1 0.021 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 VBB30933.1 - 0.03 13.4 0.0 0.03 13.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 VBB30933.1 - 0.062 12.6 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 KaiC YqfD PF06898.11 VBB30933.1 - 0.08 11.8 6.9 0.18 10.6 6.9 1.5 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD ResIII PF04851.15 VBB30933.1 - 0.092 12.7 0.1 0.092 12.7 0.1 3.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Sdh_cyt PF01127.22 VBB30934.1 - 3e-20 72.5 5.0 4.4e-20 71.9 5.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Bcl-2 PF00452.19 VBB30935.1 - 2e-13 50.8 0.2 4.2e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family WbqC PF08889.11 VBB30935.1 - 0.0015 18.4 0.1 0.0034 17.3 0.1 1.5 1 1 0 1 1 1 1 WbqC-like protein family BH4 PF02180.17 VBB30935.1 - 0.022 14.6 0.7 0.046 13.5 0.1 1.8 2 0 0 2 2 2 0 Bcl-2 homology region 4 Y1_Tnp PF01797.16 VBB30935.1 - 0.043 13.9 0.5 0.51 10.5 0.2 2.3 1 1 1 2 2 2 0 Transposase IS200 like Bcl-2 PF00452.19 VBB30936.1 - 1.4e-14 54.6 0.2 3.5e-14 53.3 0.1 1.7 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 VBB30936.1 - 0.021 14.6 1.0 0.68 9.8 0.5 2.7 2 1 0 2 2 2 0 Bcl-2 homology region 4 Membralin PF09746.9 VBB30937.1 - 6.9e-158 525.7 3.6 8.4e-158 525.4 3.6 1.1 1 0 0 1 1 1 1 Tumour-associated protein MTS PF05175.14 VBB30938.1 - 9.5e-14 51.3 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 VBB30938.1 - 0.00015 21.2 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 VBB30938.1 - 0.00062 19.5 0.0 0.00088 19.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 VBB30938.1 - 0.0031 18.2 0.0 0.0071 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB30938.1 - 0.032 14.1 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FSH1 PF03959.13 VBB30939.1 - 3.8e-50 170.5 0.1 4.6e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 VBB30939.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Methyltransf_24 PF13578.6 VBB30939.1 - 0.036 15.1 0.0 12 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.7 VBB30939.1 - 0.048 14.2 0.0 0.063 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 VBB30939.1 - 0.05 13.4 0.1 0.16 11.8 0.1 1.8 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 VBB30939.1 - 0.053 13.6 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain ATPgrasp_N PF18130.1 VBB30939.1 - 0.17 12.4 0.0 1.6 9.3 0.0 2.4 2 1 0 2 2 2 0 ATP-grasp N-terminal domain AAA_26 PF13500.6 VBB30940.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 VBB30941.1 - 1.2e-20 71.3 3.4 2.3e-06 26.9 0.0 3.5 3 0 0 3 3 3 3 IQ calmodulin-binding motif RIIa PF02197.17 VBB30941.1 - 1.5e-06 27.7 0.1 3.1e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Trypan_glycop PF00913.19 VBB30941.1 - 0.12 11.6 0.8 0.14 11.4 0.1 1.3 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Ig_3 PF13927.6 VBB30942.1 - 2.8e-50 168.8 13.5 3.5e-10 40.3 0.8 6.3 6 0 0 6 6 5 5 Immunoglobulin domain Ig_2 PF13895.6 VBB30942.1 - 1.3e-39 134.3 9.1 8.6e-09 35.6 0.2 6.1 5 1 1 6 6 6 5 Immunoglobulin domain I-set PF07679.16 VBB30942.1 - 1.9e-35 120.8 1.5 1.7e-09 37.6 0.0 7.6 5 3 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 VBB30942.1 - 2.1e-25 88.7 8.9 1.2e-05 25.3 0.0 7.3 6 2 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 VBB30942.1 - 2.9e-09 37.1 14.3 0.046 13.9 0.0 8.5 6 4 2 8 8 8 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB30942.1 - 1.5e-08 34.6 2.8 0.087 12.9 0.0 5.4 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB30942.1 - 6.5e-08 32.0 0.6 0.0074 15.8 0.1 4.3 4 0 0 4 4 4 2 Immunoglobulin domain fn3 PF00041.21 VBB30942.1 - 5.1e-07 29.9 0.1 1.2e-05 25.6 0.1 2.7 1 1 0 1 1 1 1 Fibronectin type III domain Comm PF15957.5 VBB30942.1 - 0.018 15.4 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 Commissureless TMEM154 PF15102.6 VBB30942.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family RSN1_TM PF13967.6 VBB30942.1 - 0.13 12.0 0.3 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport THAP PF05485.12 VBB30943.1 - 0.00031 21.6 0.3 0.00092 20.1 0.1 1.9 2 0 0 2 2 2 1 THAP domain MazE_antitoxin PF04014.18 VBB30943.1 - 0.03 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin BLM10_mid PF16507.5 VBB30944.1 - 9.1e-71 239.1 10.2 4.9e-68 230.1 10.2 3.6 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 VBB30944.1 - 1.1e-34 118.2 0.1 4.9e-34 116.1 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 VBB30944.1 - 0.0021 18.5 1.0 4.4 7.9 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 VBB30944.1 - 0.0095 16.1 0.1 0.25 11.7 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Methyltr_RsmB-F PF01189.17 VBB30946.1 - 1.6e-37 129.2 0.1 7.4e-37 126.9 0.0 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 VBB30946.1 - 1.9e-06 27.7 0.0 5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB30946.1 - 4.1e-06 27.4 0.0 3.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB30946.1 - 0.00032 20.1 0.0 0.00069 19.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF4512 PF14975.6 VBB30946.1 - 0.0016 19.1 7.1 0.003 18.3 6.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) PCMT PF01135.19 VBB30946.1 - 0.0024 17.6 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 VBB30946.1 - 0.047 12.8 0.0 0.13 11.3 0.0 1.7 1 1 1 2 2 2 0 Fibrillarin FtsJ PF01728.19 VBB30946.1 - 0.052 13.7 0.8 0.12 12.5 0.1 2.0 2 1 0 2 2 2 0 FtsJ-like methyltransferase Recombinase PF07508.13 VBB30946.1 - 0.07 13.5 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 Recombinase Aa_trans PF01490.18 VBB30948.1 - 8.2e-64 215.8 24.5 2.7e-38 131.7 8.4 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Ribosomal_L15e PF00827.17 VBB30949.1 - 1.3e-90 302.3 12.5 1.5e-90 302.1 12.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 DEAD PF00270.29 VBB30950.1 - 1.6e-39 135.5 0.6 1.6e-39 135.5 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB30950.1 - 2.4e-24 85.8 5.6 2e-23 82.8 0.2 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 VBB30950.1 - 0.045 14.0 3.1 0.99 9.7 0.8 3.6 3 1 0 3 3 3 0 AAA domain Aldolase_II PF00596.21 VBB30951.1 - 1.5e-45 155.5 0.6 1.1e-42 146.1 0.0 2.4 2 0 0 2 2 2 2 Class II Aldolase and Adducin N-terminal domain Glyco_hydro_38N PF01074.22 VBB30952.1 - 1.2e-73 248.0 0.3 1.9e-73 247.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 VBB30952.1 - 4.1e-44 151.2 0.0 5.8e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 VBB30952.1 - 4.1e-17 62.1 0.0 8.7e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 VBB30952.1 - 6.9e-06 26.1 0.0 1.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 VBB30952.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CBM53 PF16760.5 VBB30952.1 - 1.2 9.8 3.7 25 5.5 0.0 3.5 3 0 0 3 3 3 0 Starch/carbohydrate-binding module (family 53) ECH_1 PF00378.20 VBB30953.1 - 8.4e-87 290.6 0.1 1e-86 290.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 VBB30953.1 - 1.4e-35 123.4 0.3 1.9e-29 103.2 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 VBB30953.1 - 0.00024 21.1 0.1 0.093 12.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Patched PF02460.18 VBB30953.1 - 0.00038 18.7 0.1 0.00045 18.4 0.1 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB30953.1 - 0.032 14.1 0.2 0.056 13.3 0.2 1.4 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Helicase_C_2 PF13307.6 VBB30954.1 - 1.7e-39 135.8 0.3 3.8e-39 134.6 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain RhoGAP PF00620.27 VBB30955.1 - 8e-20 71.2 1.7 4.6e-19 68.7 0.0 2.8 2 1 0 2 2 2 1 RhoGAP domain BAR PF03114.18 VBB30955.1 - 4.7e-07 29.7 10.4 7e-07 29.1 10.4 1.3 1 0 0 1 1 1 1 BAR domain PDZ_6 PF17820.1 VBB30956.1 - 0.00012 21.9 0.1 0.64 9.9 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 VBB30956.1 - 0.0014 19.1 0.1 0.003 18.0 0.1 1.6 1 0 0 1 1 1 1 PH domain Elong-fact-P_C PF09285.11 VBB30956.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P, C-terminal DUF727 PF05303.12 VBB30957.1 - 3.1e-30 104.3 0.1 6.4e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF727) adh_short PF00106.25 VBB30958.1 - 1.6e-45 155.0 0.1 1.9e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB30958.1 - 1.3e-28 100.2 0.0 1.7e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB30958.1 - 8.1e-07 29.1 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 VBB30958.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ribosomal_S9 PF00380.19 VBB30960.1 - 3e-34 118.1 0.5 5.3e-34 117.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 F-box PF00646.33 VBB30960.1 - 0.00058 19.7 0.2 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain Amidase_3 PF01520.18 VBB30960.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Ig_3 PF13927.6 VBB30961.1 - 8.8e-40 135.2 0.0 4.2e-09 36.9 0.0 5.9 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 VBB30961.1 - 5.4e-35 119.3 0.1 1.6e-08 34.5 0.0 6.3 6 1 0 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB30961.1 - 1.3e-26 92.8 0.1 2.2e-05 24.7 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 VBB30961.1 - 3.3e-24 85.0 5.9 2.8e-07 30.8 0.2 5.3 4 1 0 4 4 4 3 Fibronectin type III domain ig PF00047.25 VBB30961.1 - 2.2e-21 75.8 0.0 1.6e-05 25.0 0.0 5.7 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 VBB30961.1 - 4.7e-07 29.9 4.0 0.64 10.2 0.0 7.5 5 3 2 7 7 7 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB30961.1 - 0.0021 18.1 0.0 0.081 13.0 0.0 3.2 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain An_peroxidase PF03098.15 VBB30962.1 - 4.3e-127 424.9 0.0 5.1e-127 424.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Ribosomal_L27e PF01777.18 VBB30964.1 - 9.6e-31 106.0 3.6 3.6e-30 104.1 3.6 2.1 1 0 0 1 1 1 1 Ribosomal L27e protein family MMR_HSR1 PF01926.23 VBB30964.1 - 7.7e-16 58.2 0.1 1.9e-14 53.7 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB30964.1 - 1.3e-08 34.5 0.2 0.00018 21.0 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B KOW PF00467.29 VBB30964.1 - 2e-06 27.6 0.0 5.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 KOW motif RsgA_GTPase PF03193.16 VBB30964.1 - 2.3e-05 24.4 0.7 0.011 15.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase cobW PF02492.19 VBB30964.1 - 0.047 13.3 0.1 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Spectrin PF00435.21 VBB30965.1 - 0 1340.1 230.6 3.6e-25 88.5 7.0 21.2 21 0 0 21 21 21 20 Spectrin repeat EFhand_Ca_insen PF08726.10 VBB30965.1 - 4.4e-27 94.0 3.2 1.6e-25 89.0 0.1 4.1 4 0 0 4 4 4 1 Ca2+ insensitive EF hand SH3_1 PF00018.28 VBB30965.1 - 1.8e-15 56.2 0.1 6.2e-15 54.5 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB30965.1 - 2e-10 40.3 0.0 5.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB30965.1 - 1.7e-09 37.2 0.0 5.2e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_1 PF00036.32 VBB30965.1 - 2.5e-09 36.0 0.3 0.00048 19.5 0.0 3.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 VBB30965.1 - 3.2e-08 33.9 0.1 3.2e-08 33.9 0.1 4.7 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB30965.1 - 5.3e-07 29.1 0.1 0.021 14.7 0.1 4.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 VBB30965.1 - 7.4e-05 22.5 1.1 0.026 14.3 0.0 4.0 3 1 1 4 4 4 1 EF-hand domain pair GvpG PF05120.12 VBB30965.1 - 0.00033 20.6 6.6 0.36 10.9 0.1 5.5 3 0 0 3 3 3 1 Gas vesicle protein G SH3_10 PF17902.1 VBB30965.1 - 0.009 16.1 0.0 0.033 14.3 0.0 2.0 1 0 0 1 1 1 1 SH3 domain Lyase_aromatic PF00221.19 VBB30965.1 - 0.012 14.3 0.0 0.055 12.1 0.0 2.1 2 0 0 2 2 2 0 Aromatic amino acid lyase GlcNAc-1_reg PF18440.1 VBB30965.1 - 0.11 12.8 1.4 1.3 9.3 0.1 3.1 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain zf-MIZ PF02891.20 VBB30965.1 - 0.73 9.6 4.7 10 6.0 0.4 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF5616 PF18481.1 VBB30965.1 - 1.6 9.1 8.7 53 4.1 0.0 6.2 7 0 0 7 7 6 0 Domain of unknown function (DUF5616) DASH_Dam1 PF08653.10 VBB30965.1 - 2.9 7.8 12.5 9 6.2 0.1 6.4 6 0 0 6 6 6 0 DASH complex subunit Dam1 RdRP PF05183.12 VBB30966.1 - 5.9e-49 167.2 0.1 7.9e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Arm PF00514.23 VBB30967.1 - 5.2e-15 54.9 7.1 0.021 14.9 0.0 7.3 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 VBB30967.1 - 0.019 15.3 1.8 0.12 12.8 0.1 3.0 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 VBB30967.1 - 0.023 14.9 0.2 0.97 9.9 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.7 VBB30967.1 - 0.094 12.8 1.1 0.66 10.0 0.2 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 T2SSF PF00482.23 VBB30967.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF3636 PF12331.8 VBB30967.1 - 0.16 11.8 2.9 0.52 10.1 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) HMG_box PF00505.19 VBB30968.1 - 5.4e-17 62.0 1.0 1.4e-16 60.7 1.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box DUF4819 PF16090.5 VBB30968.1 - 9.9e-15 54.4 2.2 1.6e-14 53.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4819) HMG_box_2 PF09011.10 VBB30968.1 - 1.2e-08 35.4 0.2 4.5e-08 33.6 0.2 2.0 1 0 0 1 1 1 1 HMG-box domain Kunitz_BPTI PF00014.23 VBB30969.1 - 9e-20 70.7 18.5 4e-14 52.6 12.8 2.0 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain APG5 PF04106.12 VBB30970.1 - 4.1e-42 144.3 2.8 9.5e-42 143.1 2.8 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 Anoct_dimer PF16178.5 VBB30970.1 - 0.077 12.7 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Calponin PF00402.18 VBB30971.1 - 5.5e-63 208.2 31.4 2e-13 49.7 2.2 7.3 7 0 0 7 7 7 7 Calponin family repeat Pro-rich PF15240.6 VBB30971.1 - 0.13 12.5 8.8 0.19 12.0 8.0 1.6 1 1 0 1 1 1 0 Proline-rich TPR_2 PF07719.17 VBB30972.1 - 3.7e-32 107.8 6.6 0.00054 19.9 0.0 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 VBB30972.1 - 3.2e-27 93.2 13.1 0.0017 18.1 0.0 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 VBB30972.1 - 3.2e-20 71.1 0.0 0.28 12.1 0.0 8.7 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 VBB30972.1 - 1.7e-19 68.3 5.7 0.0062 16.7 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 VBB30972.1 - 4.6e-17 62.1 4.7 0.0034 17.6 0.0 7.2 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 VBB30972.1 - 2.5e-15 56.7 0.1 0.045 14.3 0.0 5.8 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 VBB30972.1 - 7.3e-14 51.1 1.5 0.36 11.3 0.0 7.4 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 VBB30972.1 - 4.8e-11 43.1 0.0 0.031 14.9 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB30972.1 - 1.4e-10 40.5 1.4 0.22 11.6 0.0 7.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB30972.1 - 7.2e-10 38.4 0.0 0.036 13.8 0.1 6.2 6 1 1 7 7 7 3 TPR repeat ANAPC3 PF12895.7 VBB30972.1 - 1.4e-08 34.9 14.3 0.0037 17.5 0.3 5.1 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 VBB30972.1 - 2.2e-08 34.2 0.1 0.28 11.4 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB30972.1 - 3.1e-08 33.8 3.2 4.9 8.0 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB30972.1 - 0.00049 20.1 3.6 0.5 10.5 0.0 4.7 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 VBB30972.1 - 0.00071 19.1 0.3 0.0023 17.4 0.0 1.8 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_10 PF13374.6 VBB30972.1 - 0.00079 19.2 1.0 2.5 8.1 0.0 5.1 6 1 1 7 7 6 1 Tetratricopeptide repeat PPR PF01535.20 VBB30972.1 - 0.0015 18.6 1.8 0.32 11.4 0.0 5.0 6 0 0 6 6 6 1 PPR repeat RPN7 PF10602.9 VBB30972.1 - 0.0061 16.3 1.9 3.3 7.4 0.0 4.4 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_15 PF13429.6 VBB30972.1 - 0.015 14.6 0.1 0.27 10.4 0.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat E2F_CC-MB PF16421.5 VBB30972.1 - 0.033 14.6 0.0 0.23 11.8 0.0 2.4 2 1 1 3 3 2 0 E2F transcription factor CC-MB domain PPR_2 PF13041.6 VBB30972.1 - 0.068 13.4 0.5 0.63 10.3 0.0 2.9 3 0 0 3 3 2 0 PPR repeat family Phosphodiest PF01663.22 VBB30974.1 - 1.3e-15 57.9 1.5 4.5e-15 56.1 1.2 2.0 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 VBB30974.1 - 1.3e-05 24.7 0.1 2.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 VBB30974.1 - 0.011 15.1 0.5 0.04 13.3 0.1 2.2 3 0 0 3 3 3 0 Sulfatase PglZ PF08665.12 VBB30974.1 - 0.2 11.7 3.5 5.3 7.1 0.0 3.1 3 0 0 3 3 3 0 PglZ domain FARP PF01581.16 VBB30974.1 - 2.5 9.0 3.8 60 4.8 0.0 3.9 3 0 0 3 3 3 0 FMRFamide related peptide family NOG1_N PF17835.1 VBB30975.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Motile_Sperm PF00635.26 VBB30976.1 - 1.8e-30 105.0 0.1 2.8e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain KASH_CCD PF14662.6 VBB30976.1 - 0.088 12.6 0.2 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH zf-CXXC PF02008.20 VBB30977.1 - 4.1 7.5 17.6 8.3 6.5 8.2 2.2 2 0 0 2 2 2 0 CXXC zinc finger domain Allatostatin PF05953.12 VBB30977.1 - 4.3 8.3 9.3 1.7e+02 3.4 0.1 4.8 5 0 0 5 5 5 0 Allatostatin Sugar_tr PF00083.24 VBB30978.1 - 1.3e-25 90.2 1.8 1.8e-25 89.7 1.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2181 PF10223.9 VBB30978.1 - 4.5e-17 62.3 0.0 7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) MFS_1 PF07690.16 VBB30978.1 - 4e-09 35.9 1.2 4e-09 35.9 1.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.8 VBB30978.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AAA PF00004.29 VBB30979.1 - 1e-49 168.3 0.0 1.9e-43 148.1 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB30979.1 - 3.9e-15 55.4 0.1 2.8e-08 33.4 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 VBB30979.1 - 1.4e-08 35.3 0.6 0.0076 16.6 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 VBB30979.1 - 8.5e-08 32.1 0.0 0.013 15.2 0.0 3.3 3 1 1 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 VBB30979.1 - 5.5e-07 29.7 0.3 0.00034 20.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 VBB30979.1 - 2e-06 28.2 0.0 0.006 16.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SSE PF00437.20 VBB30979.1 - 6.8e-05 22.1 0.1 0.00034 19.8 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_2 PF07724.14 VBB30979.1 - 0.00045 20.4 0.0 0.0086 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 VBB30979.1 - 0.00072 18.9 0.0 0.0047 16.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain Bac_DnaA PF00308.18 VBB30979.1 - 0.0013 18.6 1.1 0.12 12.2 0.0 3.5 2 2 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.13 VBB30979.1 - 0.0015 17.7 0.0 0.21 10.7 0.0 3.3 4 0 0 4 4 3 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 VBB30979.1 - 0.0019 18.7 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 VBB30979.1 - 0.002 17.8 0.4 6.2 6.3 0.1 3.3 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 VBB30979.1 - 0.002 18.3 0.0 0.065 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 VBB30979.1 - 0.0021 18.0 0.4 0.69 9.8 0.1 3.7 3 1 1 4 4 4 1 NACHT domain AAA_22 PF13401.6 VBB30979.1 - 0.0024 18.1 3.2 4.5 7.5 0.0 4.4 3 2 2 5 5 5 1 AAA domain Sigma54_activat PF00158.26 VBB30979.1 - 0.0025 17.6 0.0 2.7 7.7 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain TsaE PF02367.17 VBB30979.1 - 0.005 16.8 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 VBB30979.1 - 0.0069 16.3 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 VBB30979.1 - 0.012 15.0 0.0 0.67 9.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 VBB30979.1 - 0.032 13.5 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 VBB30979.1 - 0.05 12.8 0.0 12 5.0 0.1 2.9 2 1 1 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 VBB30979.1 - 0.067 13.1 0.4 19 5.1 0.0 3.6 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 VBB30979.1 - 0.067 12.7 0.1 14 5.1 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 VBB30979.1 - 0.084 13.4 0.0 4.9 7.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.6 VBB30979.1 - 0.11 12.6 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 VBB30979.1 - 0.17 11.6 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DAP3 PF10236.9 VBB30979.1 - 0.18 10.9 0.0 0.45 9.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 GluR_Homer-bdg PF10606.9 VBB30980.1 - 0.12 12.6 0.6 0.12 12.6 0.6 2.6 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Ribosomal_L32e PF01655.18 VBB30981.1 - 1.4e-50 170.2 3.5 1.8e-50 169.9 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 GTP_EFTU PF00009.27 VBB30983.1 - 5.3e-59 199.0 0.0 1e-58 198.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 VBB30983.1 - 7.1e-35 119.4 0.1 3.3e-34 117.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 VBB30983.1 - 4.5e-22 77.9 0.0 1.1e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 VBB30983.1 - 5.2e-14 52.1 0.0 1.4e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 VBB30983.1 - 2e-11 44.1 0.1 5.1e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 VBB30983.1 - 8.8e-05 22.6 0.1 0.00027 21.0 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Tetraspanin PF00335.20 VBB30983.1 - 0.046 13.4 0.8 0.075 12.7 0.8 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4317 PF14199.6 VBB30983.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Elf1 PF05129.13 VBB30984.1 - 6e-29 99.9 2.3 1.8e-28 98.4 2.3 1.9 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF241 PF03087.14 VBB30984.1 - 0.035 13.9 0.3 0.094 12.5 0.3 1.7 1 0 0 1 1 1 0 Arabidopsis protein of unknown function hDGE_amylase PF14701.6 VBB30985.1 - 3.8e-143 477.7 0.7 7.5e-143 476.8 0.7 1.5 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 VBB30985.1 - 5.8e-120 400.7 0.1 1e-119 399.9 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 VBB30985.1 - 5.3e-61 206.5 0.0 7.4e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Alpha-amylase PF00128.24 VBB30985.1 - 0.012 15.2 0.3 0.027 14.0 0.1 1.7 2 0 0 2 2 2 0 Alpha amylase, catalytic domain DUF4974 PF16344.5 VBB30985.1 - 0.15 12.1 0.7 4.8 7.3 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) PDZ PF00595.24 VBB30986.1 - 6.1e-13 48.9 1.8 3.4e-10 40.1 0.5 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB30986.1 - 4.5e-09 36.0 0.4 1e-07 31.7 0.2 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 VBB30986.1 - 0.00036 20.8 2.3 0.036 14.4 0.1 3.4 3 0 0 3 3 3 1 PDZ domain RTP1_C2 PF10304.9 VBB30986.1 - 0.048 13.4 0.8 0.14 11.8 0.8 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 PBP1_TM PF14812.6 VBB30986.1 - 4.3 7.8 10.8 1.2 9.5 7.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PUB PF09409.10 VBB30987.1 - 8.5e-25 86.5 1.2 1.5e-24 85.7 0.7 1.7 2 0 0 2 2 2 1 PUB domain UBX PF00789.20 VBB30987.1 - 5.7e-09 36.0 0.0 2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 UBX domain Glu_synthase PF01645.17 VBB30988.1 - 1.7e-06 27.5 4.3 6.3e-05 22.3 0.0 2.9 2 1 1 3 3 3 2 Conserved region in glutamate synthase Shisa PF13908.6 VBB30989.1 - 0.0021 18.3 0.3 0.0032 17.8 0.2 1.3 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4307 PF14155.6 VBB30989.1 - 0.0021 17.9 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) TssO PF17561.2 VBB30989.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO EphA2_TM PF14575.6 VBB30989.1 - 0.017 16.0 0.2 0.028 15.3 0.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 VBB30989.1 - 0.02 15.3 0.5 0.02 15.3 0.5 1.8 2 1 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4834 PF16118.5 VBB30989.1 - 0.022 15.7 0.1 0.034 15.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ly49 PF08391.10 VBB30989.1 - 0.026 14.9 0.1 0.036 14.4 0.1 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Comm PF15957.5 VBB30989.1 - 0.035 14.5 0.1 0.051 13.9 0.1 1.4 1 1 0 1 1 1 0 Commissureless HemY_N PF07219.13 VBB30989.1 - 0.039 14.1 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Chordopox_A13L PF05961.11 VBB30989.1 - 0.047 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Tmemb_9 PF05434.11 VBB30989.1 - 0.074 12.9 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 TMEM9 TMEM52 PF14979.6 VBB30989.1 - 0.087 12.7 0.3 0.14 12.1 0.3 1.5 1 1 0 1 1 1 0 Transmembrane 52 NICE-3 PF07406.11 VBB30989.1 - 0.088 12.8 3.0 0.15 12.0 3.0 1.4 1 1 0 1 1 1 0 NICE-3 protein MLANA PF14991.6 VBB30989.1 - 0.089 13.1 1.4 0.19 12.0 1.4 1.5 1 1 0 1 1 1 0 Protein melan-A DUF3168 PF11367.8 VBB30989.1 - 0.091 12.9 0.2 0.14 12.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3168) CRA PF06589.11 VBB30989.1 - 0.097 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Baculo_11_kDa PF06143.11 VBB30989.1 - 0.1 12.2 0.4 0.18 11.4 0.4 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family ECSCR PF15820.5 VBB30989.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator WBP-1 PF11669.8 VBB30989.1 - 0.12 13.0 0.2 0.2 12.3 0.2 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 SID-1_RNA_chan PF13965.6 VBB30989.1 - 0.23 9.8 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SCIMP PF15050.6 VBB30989.1 - 0.25 11.8 3.9 0.89 10.0 3.9 2.0 1 1 0 1 1 1 0 SCIMP protein ODV-E18 PF10717.9 VBB30989.1 - 0.28 11.1 1.1 0.6 10.0 0.7 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 TMEM154 PF15102.6 VBB30989.1 - 0.91 9.4 3.8 0.7 9.8 1.9 1.8 1 1 0 1 1 1 0 TMEM154 protein family Hanta_G2 PF01561.16 VBB30989.1 - 1.1 7.8 2.1 1.7 7.2 2.1 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 OAD_gamma PF04277.13 VBB30989.1 - 1.5 9.5 6.1 7.4 7.2 6.2 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Sec61_beta PF03911.16 VBB30989.1 - 2.8 8.0 7.2 5.5 7.1 7.2 1.4 1 0 0 1 1 1 0 Sec61beta family Orf78 PF06024.12 VBB30989.1 - 9.3 6.6 6.2 7 7.0 4.6 1.6 1 1 1 2 2 2 0 Orf78 (ac78) PDZ PF00595.24 VBB30990.1 - 4.7e-59 196.7 4.2 5e-19 68.4 0.1 3.5 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 VBB30990.1 - 3.9e-51 173.3 0.0 9.1e-51 172.1 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase PDZ_6 PF17820.1 VBB30990.1 - 2.2e-23 81.9 0.8 5.5e-10 38.9 0.0 3.6 3 0 0 3 3 3 3 PDZ domain L27_1 PF09058.10 VBB30990.1 - 6.4e-23 80.5 0.6 1.5e-22 79.3 0.6 1.7 1 0 0 1 1 1 1 L27_1 PDZ_2 PF13180.6 VBB30990.1 - 3.6e-13 49.7 0.7 0.0048 17.2 0.0 3.7 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.28 VBB30990.1 - 1.8e-06 27.4 0.0 4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB30990.1 - 1.9e-05 24.3 0.0 4.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.6 VBB30990.1 - 0.063 13.3 0.7 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Tricorn protease PDZ domain SH3_9 PF14604.6 VBB30990.1 - 0.094 12.6 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Vezatin PF12632.7 VBB30990.1 - 0.1 11.9 0.3 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DBD_HTH PF18430.1 VBB30990.1 - 0.26 11.1 0.7 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative DNA-binding domain BACK PF07707.15 VBB30991.1 - 6.9e-07 29.3 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 VBB30991.1 - 0.002 18.4 0.1 0.0042 17.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-TRAF_2 PF15965.5 VBB30992.1 - 7.1e-24 84.1 27.3 7.1e-24 84.1 27.3 3.1 3 1 0 3 3 3 1 TRAF-like zinc-finger F-box_4 PF15966.5 VBB30992.1 - 6.3e-23 80.9 0.8 6.3e-23 80.9 0.8 2.9 3 1 0 3 3 3 1 F-box F-box PF00646.33 VBB30992.1 - 2.2e-05 24.2 0.7 7e-05 22.6 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 VBB30992.1 - 3.8e-05 23.5 0.8 8.1e-05 22.4 0.8 1.6 1 0 0 1 1 1 1 F-box-like IL17 PF06083.11 VBB30993.1 - 0.041 14.4 0.8 0.12 12.9 0.8 1.8 1 0 0 1 1 1 0 Interleukin-17 Spectrin PF00435.21 VBB30994.1 - 1.9e-16 60.4 101.7 7.8e-09 36.0 8.5 14.6 9 5 4 14 14 14 5 Spectrin repeat CH PF00307.31 VBB30994.1 - 9.1e-11 41.9 0.0 9.1e-11 41.9 0.0 4.7 6 0 0 6 6 6 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB30994.1 - 0.00097 18.9 0.1 0.0071 16.2 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain GlcNAc-1_reg PF18440.1 VBB30994.1 - 0.015 15.5 1.2 5.1 7.4 0.2 3.3 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain NPV_P10 PF05531.12 VBB30994.1 - 0.037 14.5 0.4 0.037 14.5 0.4 9.5 9 2 2 11 11 11 0 Nucleopolyhedrovirus P10 protein PdxA PF04166.12 VBB30994.1 - 0.038 13.4 2.1 0.039 13.4 0.4 1.9 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA DUF2280 PF10045.9 VBB30994.1 - 0.081 13.2 0.6 3.6 7.9 0.1 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) HsbA PF12296.8 VBB30994.1 - 0.1 13.0 5.7 3.2 8.2 0.1 5.6 7 0 0 7 7 6 0 Hydrophobic surface binding protein A SCO1-SenC PF02630.14 VBB30994.1 - 0.1 12.5 1.8 58 3.6 0.1 4.2 3 1 1 4 4 4 0 SCO1/SenC Phage_int_SAM_1 PF02899.17 VBB30994.1 - 0.19 12.0 5.6 9 6.7 0.1 5.2 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain NRN1 PF15056.6 VBB30994.1 - 0.27 11.3 12.6 0.89 9.7 0.2 5.4 5 0 0 5 5 5 0 Neuritin protein family DinB_2 PF12867.7 VBB30994.1 - 2.3 8.8 9.5 19 5.8 0.0 5.6 5 3 0 5 5 5 0 DinB superfamily DUF3584 PF12128.8 VBB30994.1 - 3.9 4.9 101.2 0.0069 14.0 25.1 5.7 2 2 3 5 5 5 0 Protein of unknown function (DUF3584) Metal_resist PF13801.6 VBB30994.1 - 4.9 7.4 14.1 0.23 11.7 3.2 4.1 3 0 0 3 3 3 0 Heavy-metal resistance C6 PF01681.17 VBB30995.1 - 2.8e-10 40.6 22.6 0.00012 22.6 0.8 4.9 4 1 0 4 4 4 3 C6 domain TSP_1 PF00090.19 VBB30995.1 - 5.9e-06 26.4 9.5 5.9e-06 26.4 9.5 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain EF-hand_1 PF00036.32 VBB30996.1 - 2.6e-23 79.8 9.7 1.8e-07 30.2 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB30996.1 - 4.3e-21 75.2 5.4 2e-11 44.2 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB30996.1 - 3.2e-20 70.3 5.2 1.8e-06 27.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 VBB30996.1 - 3.9e-16 58.6 7.1 5.4e-07 29.4 0.6 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 VBB30996.1 - 1e-10 41.7 0.3 5.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 VBB30996.1 - 1.1e-09 37.3 8.2 0.00011 21.5 0.0 3.5 5 0 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 VBB30996.1 - 3.1e-08 33.5 2.8 0.0046 16.9 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 VBB30996.1 - 0.0039 17.5 0.8 0.67 10.3 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 VBB30996.1 - 0.016 15.5 0.0 0.048 14.0 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain EF-hand_11 PF08976.11 VBB30996.1 - 0.027 15.3 0.1 0.19 12.6 0.0 2.1 1 1 0 2 2 2 0 EF-hand domain DUF2408 PF10303.9 VBB30996.1 - 0.089 13.4 0.2 0.17 12.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) F-box-like PF12937.7 VBB30997.1 - 1.8e-10 40.5 0.6 4.7e-10 39.2 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB30997.1 - 1.5e-06 27.9 0.1 5e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 VBB30997.1 - 0.016 15.2 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain LRR_6 PF13516.6 VBB30997.1 - 0.69 10.1 3.8 31 5.0 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Fez1 PF06818.15 VBB30998.1 - 3e-09 37.6 12.5 9.7e-09 36.0 12.5 1.9 1 1 0 1 1 1 1 Fez1 Macoilin PF09726.9 VBB30998.1 - 0.00091 17.9 16.4 0.0019 16.8 11.0 2.2 2 0 0 2 2 2 1 Macoilin family DUF4201 PF13870.6 VBB30998.1 - 0.0046 16.7 6.8 0.0046 16.7 6.8 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) Hydantoinase_B PF02538.14 VBB30998.1 - 0.026 13.0 0.8 0.044 12.2 0.8 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF5137 PF17220.3 VBB30998.1 - 0.054 14.4 0.2 0.054 14.4 0.2 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF5137) Spc7 PF08317.11 VBB30998.1 - 0.076 11.9 20.4 0.043 12.7 8.9 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein GOLGA2L5 PF15070.6 VBB30998.1 - 0.11 11.1 12.9 0.39 9.3 9.2 2.2 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Cluap1 PF10234.9 VBB30998.1 - 0.14 11.5 8.8 0.033 13.6 4.8 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF2353 PF09789.9 VBB30998.1 - 0.14 11.5 14.8 0.12 11.8 12.7 1.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Cnn_1N PF07989.11 VBB30998.1 - 0.16 12.1 10.0 9.2 6.5 5.9 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Lebercilin PF15619.6 VBB30998.1 - 0.5 10.0 18.2 10 5.8 0.2 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tho2 PF11262.8 VBB30998.1 - 0.75 8.9 7.3 0.17 11.0 1.2 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HIP1_clath_bdg PF16515.5 VBB30998.1 - 0.92 10.2 17.9 0.35 11.5 7.5 3.4 4 0 0 4 4 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 VBB30998.1 - 0.96 9.5 24.2 0.13 12.3 3.3 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 VBB30998.1 - 1 9.9 8.6 8.9 6.8 0.1 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 VBB30998.1 - 1.1 9.3 8.2 3.3 7.8 5.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 VBB30998.1 - 1.2 9.4 20.8 4.2 7.6 11.5 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TSC22 PF01166.18 VBB30998.1 - 1.3 9.4 10.1 29 5.1 0.2 4.1 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF4407 PF14362.6 VBB30998.1 - 2.2 7.5 9.6 13 5.0 9.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 VBB30998.1 - 2.6 7.5 20.8 15 5.1 15.4 2.8 1 1 0 2 2 2 0 Intermediate filament protein RNA_pol_Rbc25 PF08292.12 VBB30998.1 - 3.1 8.1 5.0 4.1 7.7 2.2 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 UPF0242 PF06785.11 VBB30998.1 - 4.2 7.4 13.7 1.9 8.6 8.1 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GrpE PF01025.19 VBB30998.1 - 8.3 6.1 14.4 0.27 10.9 0.5 3.0 2 1 1 3 3 3 0 GrpE Fibroin_P25 PF07294.11 VBB30999.1 - 0.0082 16.2 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 Fibroin P25 FKBP_C PF00254.28 VBB31000.1 - 1.5e-52 175.9 0.0 1.4e-27 95.9 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 VBB31002.1 - 1.9e-34 119.2 0.0 4.1e-34 118.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31002.1 - 1.9e-16 60.2 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31002.1 - 5.5e-07 29.2 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB31002.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ground-like PF04155.18 VBB31003.1 - 3.1e-20 72.6 4.3 6.7e-20 71.5 4.3 1.6 1 0 0 1 1 1 1 Ground-like domain Ground-like PF04155.18 VBB31004.1 - 1.1e-14 54.8 0.8 1.1e-14 54.8 0.8 1.7 2 0 0 2 2 2 1 Ground-like domain Kunitz_BPTI PF00014.23 VBB31005.1 - 6e-120 391.4 40.0 6.7e-18 64.7 0.8 8.4 8 0 0 8 8 8 8 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 VBB31005.1 - 1.1e-50 169.7 101.0 3.5e-08 33.7 5.6 9.7 9 1 0 9 9 9 7 Lustrin, cysteine-rich repeated domain SAD_SRA PF02182.17 VBB31005.1 - 0.078 12.7 0.0 75 3.0 0.0 4.2 5 0 0 5 5 5 0 SAD/SRA domain zf-C4 PF00105.18 VBB31006.1 - 5.7e-32 110.0 15.2 1.1e-31 109.1 15.2 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB31006.1 - 1.4e-06 28.0 1.1 1.4e-06 28.0 1.1 2.0 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor G-alpha PF00503.20 VBB31007.1 - 3.6e-42 144.8 7.1 5.9e-42 144.1 7.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB31007.1 - 3.9e-15 55.7 0.2 9.5e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB31007.1 - 1.5e-05 24.5 0.2 4.4e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 VBB31007.1 - 0.00013 22.5 0.0 0.0003 21.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 VBB31007.1 - 0.00051 20.3 0.0 0.7 10.1 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 VBB31007.1 - 0.0013 18.8 0.1 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 VBB31007.1 - 0.0028 18.1 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 VBB31007.1 - 0.0072 15.9 1.9 2.7 7.6 0.0 3.1 2 1 1 3 3 3 2 Ras family DUF4363 PF14276.6 VBB31007.1 - 0.049 13.7 0.8 0.1 12.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) SRPRB PF09439.10 VBB31007.1 - 0.092 12.2 8.1 0.76 9.2 0.2 3.3 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit NYD-SP28 PF14772.6 VBB31007.1 - 0.14 12.3 0.6 0.32 11.1 0.6 1.5 1 0 0 1 1 1 0 Sperm tail Pkinase PF00069.25 VBB31008.1 - 1.3e-65 221.4 0.0 2e-50 171.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31008.1 - 3.1e-25 88.9 0.0 3.2e-24 85.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 VBB31008.1 - 1e-05 25.0 0.3 1.8e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB31008.1 - 8.3e-05 22.0 0.0 0.00043 19.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 VBB31008.1 - 0.00097 18.8 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 VBB31008.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HI0933_like PF03486.14 VBB31008.1 - 0.2 10.3 0.5 0.61 8.7 0.5 1.7 1 1 0 1 1 1 0 HI0933-like protein Ribosomal_L14e PF01929.17 VBB31009.1 - 7.3e-16 58.4 1.1 1e-15 58.0 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 NUC153 PF08159.12 VBB31010.1 - 5.7e-08 32.4 4.9 1.1e-06 28.3 0.1 4.3 5 0 0 5 5 5 2 NUC153 domain tRNA-synt_1g PF09334.11 VBB31011.1 - 3.4e-134 447.5 0.2 4.6e-134 447.0 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 VBB31011.1 - 3.6e-31 107.1 0.1 8.1e-31 106.0 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 VBB31011.1 - 2.3e-06 26.2 0.2 0.00068 18.0 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) CIAPIN1 PF05093.13 VBB31011.1 - 0.06 13.9 0.3 0.06 13.9 0.3 2.5 3 1 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zinc-ribbons_6 PF07191.12 VBB31011.1 - 4.1 7.5 8.0 9.8 6.2 8.0 1.6 1 0 0 1 1 1 0 zinc-ribbons Y_phosphatase PF00102.27 VBB31012.1 - 1.7e-37 129.2 0.2 2.3e-37 128.8 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ClpS PF02617.17 VBB31014.1 - 1.1e-21 76.3 0.1 6.4e-21 73.9 0.0 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 VBB31014.1 - 4.8e-18 65.1 15.4 4.8e-18 65.1 15.4 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 VBB31015.1 - 9.4e-45 153.0 0.0 1.4e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31015.1 - 3.4e-36 124.9 0.0 5.4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 VBB31015.1 - 2.7e-20 72.3 0.5 8.9e-20 70.7 0.5 2.0 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 VBB31015.1 - 4.1e-06 25.8 0.1 9.2e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 VBB31015.1 - 0.047 13.0 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like HU-CCDC81_bac_2 PF18175.1 VBB31015.1 - 0.18 11.7 0.1 0.49 10.3 0.1 1.7 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 CAP_N PF01213.19 VBB31016.1 - 0.027 13.9 0.9 0.048 13.1 0.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MADF_DNA_bdg PF10545.9 VBB31016.1 - 0.86 10.0 4.6 1.4 9.3 4.6 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.25 VBB31017.1 - 3.3e-50 170.9 0.2 5.9e-50 170.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31017.1 - 9.5e-31 107.0 0.0 1.5e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31017.1 - 9.5e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 VBB31017.1 - 0.046 12.8 0.1 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.22 VBB31017.1 - 0.053 13.1 0.0 0.32 10.5 0.0 2.2 3 0 0 3 3 3 0 RIO1 family APH PF01636.23 VBB31017.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 VBB31018.1 - 3.6e-11 42.9 0.1 4.4e-10 39.3 0.1 2.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 VBB31018.1 - 0.0012 18.0 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 VBB31018.1 - 0.014 14.3 0.0 0.64 8.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 VBB31018.1 - 0.033 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 VBB31018.1 - 0.065 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 VBB31018.1 - 0.075 12.3 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 VBB31018.1 - 0.083 11.9 0.6 18 4.2 0.1 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 VBB31018.1 - 0.091 13.0 0.2 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain CH PF00307.31 VBB31019.1 - 7.2e-40 135.6 3.3 2e-19 69.8 0.0 5.4 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB31019.1 - 1.7e-12 47.0 0.6 2.9e-05 23.8 0.0 4.2 3 0 0 3 3 3 2 CAMSAP CH domain DUF725 PF05267.12 VBB31019.1 - 0.38 10.8 0.0 0.38 10.8 0.0 5.4 6 1 1 7 7 7 0 Protein of unknown function (DUF725) C1_1 PF00130.22 VBB31020.1 - 0.0036 17.2 0.4 0.0063 16.4 0.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prp19 PF08606.11 VBB31021.1 - 2.6e-31 107.4 2.1 5.7e-31 106.3 2.1 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 VBB31021.1 - 4.2e-26 90.7 9.5 1.7e-06 28.6 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31021.1 - 1.6e-12 47.6 1.2 0.0056 17.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 VBB31021.1 - 1.3e-05 24.9 0.0 0.15 11.6 0.0 2.5 2 1 0 2 2 2 2 Hermansky-Pudlak syndrome 3 eIF2A PF08662.11 VBB31021.1 - 6.6e-05 22.9 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 VBB31021.1 - 7.7e-05 21.8 0.2 0.41 9.5 0.0 3.7 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 VBB31021.1 - 0.0021 16.8 0.1 0.38 9.3 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 U-box PF04564.15 VBB31021.1 - 0.0062 16.7 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain Cytochrom_D1 PF02239.16 VBB31021.1 - 0.0073 14.9 0.1 0.053 12.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Golgin_A5 PF09787.9 VBB31021.1 - 0.0078 15.7 0.8 0.011 15.2 0.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-Nse PF11789.8 VBB31021.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_MLP1_2 PF07926.12 VBB31021.1 - 1.7 8.7 5.2 0.67 10.0 2.2 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_C48 PF02902.19 VBB31022.1 - 3e-47 161.2 1.7 3e-47 161.2 1.7 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MKRN1_C PF15815.5 VBB31022.1 - 0.79 10.2 4.3 29 5.2 0.1 3.5 3 1 0 3 3 3 0 E3 ubiquitin-protein ligase makorin-1, C-terminal BSMAP PF12280.8 VBB31022.1 - 3.1 8.0 6.0 0.75 10.0 1.6 2.0 2 0 0 2 2 2 0 Brain specific membrane anchored protein Mito_carr PF00153.27 VBB31023.1 - 3.6e-59 196.7 4.6 1.6e-20 72.8 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CRAL_TRIO PF00650.20 VBB31024.1 - 5.5e-25 87.9 0.1 8.1e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Keratin PF02422.16 VBB31024.1 - 0.075 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Keratin Serum_albumin PF00273.20 VBB31025.1 - 0.056 13.2 0.2 0.064 13.0 0.2 1.1 1 0 0 1 1 1 0 Serum albumin family DUF5323 PF17257.2 VBB31026.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5323) NmrA PF05368.13 VBB31028.1 - 7.2e-14 51.9 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 VBB31028.1 - 2.8e-13 50.2 0.0 4.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 VBB31028.1 - 7e-11 42.0 0.0 1.6e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 VBB31028.1 - 1.6e-10 40.6 0.0 3.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 VBB31028.1 - 1.2e-06 27.9 0.7 0.0016 17.7 0.1 2.9 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 VBB31028.1 - 2.4e-05 23.5 0.0 0.00012 21.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family S36_mt PF10937.8 VBB31028.1 - 0.0021 19.6 2.2 0.18 13.4 1.1 2.9 2 1 0 2 2 2 1 Ribosomal protein S36, mitochondrial adh_short PF00106.25 VBB31028.1 - 0.044 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 VBB31028.1 - 0.046 12.9 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3798 PF12683.7 VBB31028.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) PsbN PF02468.15 VBB31029.1 - 0.22 11.4 1.5 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Scs3p PF10261.9 VBB31030.1 - 1.2e-10 41.3 11.1 2.6e-08 33.7 3.9 2.9 2 1 1 3 3 3 2 Inositol phospholipid synthesis and fat-storage-inducing TM Arylesterase PF01731.20 VBB31030.1 - 0.013 15.6 0.6 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Arylesterase Peptidase_C15 PF01470.17 VBB31031.1 - 4.1e-13 50.0 0.0 5.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 VBB31031.1 - 1.3e-11 44.6 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 IGFL PF14653.6 VBB31031.1 - 0.0045 16.9 0.5 0.011 15.6 0.5 1.7 1 0 0 1 1 1 1 Insulin growth factor-like family AbfB PF05270.13 VBB31031.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain DUF4604 PF15377.6 VBB31032.1 - 9.3e-09 35.9 9.2 3e-07 31.0 9.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) NYD-SP12_N PF15015.6 VBB31032.1 - 0.036 12.5 4.2 0.043 12.2 4.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal zf-met2 PF12907.7 VBB31033.1 - 0.0076 16.4 0.1 0.0086 16.2 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding DUF2465 PF10239.9 VBB31034.1 - 3.9e-80 269.5 0.2 4.9e-80 269.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) KH_9 PF17904.1 VBB31034.1 - 0.15 12.5 0.2 0.39 11.1 0.2 1.6 1 0 0 1 1 1 0 FMRP KH0 domain HTH_51 PF18558.1 VBB31034.1 - 0.17 11.7 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MMR_HSR1 PF01926.23 VBB31035.1 - 1.7e-16 60.3 0.0 4.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB31035.1 - 8.7e-09 35.1 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 VBB31035.1 - 5.7e-07 29.3 0.1 1.7e-05 24.5 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB31035.1 - 1.3e-05 25.1 2.8 0.18 11.7 0.3 3.2 2 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 VBB31035.1 - 0.0038 16.7 0.1 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 VBB31035.1 - 0.046 13.8 4.3 0.67 10.0 0.2 3.2 3 1 1 4 4 4 0 Dynamin family AAA_22 PF13401.6 VBB31035.1 - 0.049 13.9 0.1 0.4 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 VBB31035.1 - 0.062 13.5 0.6 0.34 11.1 0.1 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 VBB31035.1 - 0.066 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 VBB31035.1 - 0.081 13.5 0.1 0.44 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain IMPa_helical PF18642.1 VBB31035.1 - 0.082 13.3 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain KH_2 PF07650.17 VBB31035.1 - 0.095 12.5 0.6 0.27 11.1 0.6 1.7 1 0 0 1 1 1 0 KH domain MnmE_helical PF12631.7 VBB31035.1 - 0.097 12.8 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 MnmE helical domain DUF1827 PF08860.10 VBB31035.1 - 0.1 12.9 0.4 0.44 10.8 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1827) Raptor_N PF14538.6 VBB31036.1 - 1.1e-38 132.5 0.0 2.4e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 VBB31036.1 - 4.1e-07 30.6 0.1 1.9 9.5 0.0 5.6 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.22 VBB31036.1 - 0.00054 20.0 0.0 0.0051 16.9 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat ANAPC4_WD40 PF12894.7 VBB31036.1 - 0.0046 17.2 0.2 0.31 11.4 0.2 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 VBB31036.1 - 0.025 14.9 1.4 0.096 13.1 0.6 2.4 3 0 0 3 3 3 0 HEAT repeats Pyr_redox_2 PF07992.14 VBB31037.1 - 7.4e-10 38.5 0.0 0.015 14.5 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 VBB31037.1 - 0.018 14.1 0.0 0.29 10.1 0.0 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein Kelch_1 PF01344.25 VBB31037.1 - 0.027 14.1 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Pyr_redox PF00070.27 VBB31037.1 - 0.033 14.7 0.4 5.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GLE1 PF07817.13 VBB31038.1 - 9.6e-08 31.5 2.3 1.5e-07 30.9 1.2 1.9 1 1 0 1 1 1 1 GLE1-like protein DUF3087 PF11286.8 VBB31038.1 - 0.69 9.4 3.5 0.24 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Bac_surface_Ag PF01103.23 VBB31039.1 - 3.4e-10 39.9 0.3 7.2e-10 38.9 0.3 1.5 1 1 0 1 1 1 1 Surface antigen RTTN_N PF14726.6 VBB31040.1 - 0.049 14.4 0.7 87 4.0 0.0 3.2 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning RRM_occluded PF16842.5 VBB31040.1 - 0.077 12.9 0.1 0.51 10.2 0.0 2.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif HSP20 PF00011.21 VBB31041.1 - 3.7e-21 75.2 0.3 5.3e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB31041.1 - 2.9e-06 26.7 0.0 5.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA End_beta_propel PF12217.8 VBB31041.1 - 0.19 10.4 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase zf-C2H2_4 PF13894.6 VBB31042.1 - 0.00095 19.8 21.2 0.099 13.5 5.1 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB31042.1 - 0.016 15.6 11.0 1.3 9.5 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 VBB31042.1 - 0.079 13.3 0.5 0.079 13.3 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB31042.1 - 0.089 13.2 13.1 0.21 12.0 0.8 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 VBB31042.1 - 3.6 8.0 10.5 1.3 9.4 3.0 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 VBB31042.1 - 4.1 7.3 6.7 2.6 7.9 0.3 2.6 2 0 0 2 2 2 0 GAGA factor Meleagrin PF08189.11 VBB31042.1 - 7.4 6.4 9.9 0.2 11.4 2.3 2.3 2 0 0 2 2 2 0 Meleagrin/Cygnin family 7tm_1 PF00001.21 VBB31043.1 - 2.7e-55 187.5 0.1 3.7e-55 187.1 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB31043.1 - 7.7e-09 35.3 8.7 1.2e-08 34.7 8.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 VBB31043.1 - 0.00014 21.3 8.9 0.00027 20.4 8.9 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 VBB31043.1 - 0.002 17.9 6.0 0.002 17.9 6.0 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 VBB31043.1 - 0.027 14.1 20.5 0.016 14.8 16.8 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3377 PF11857.8 VBB31043.1 - 0.73 9.8 3.7 8.5 6.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Suf PF05843.14 VBB31046.1 - 5.2e-15 56.2 9.6 9.4e-10 38.9 1.8 2.9 1 1 2 3 3 3 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 VBB31046.1 - 1e-08 35.6 0.0 0.00099 19.6 0.0 4.1 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 VBB31046.1 - 5.8e-07 29.0 0.7 0.014 14.6 0.0 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB31046.1 - 8.8e-06 26.1 0.0 1.6 9.8 0.0 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB31046.1 - 5.4e-05 23.7 0.0 2.2 9.0 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 VBB31046.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 VBB31046.1 - 0.0013 18.7 1.7 7.8 7.0 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB31046.1 - 0.0016 18.7 0.2 4.8 7.5 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB31046.1 - 0.0028 17.6 1.5 4.9 7.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 VBB31046.1 - 0.0029 18.1 5.0 0.2 12.4 0.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 VBB31046.1 - 0.0073 15.5 8.5 0.67 9.0 0.2 3.6 1 1 2 3 3 3 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 VBB31046.1 - 0.0089 16.3 0.0 4.2 8.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB31046.1 - 0.014 15.6 0.0 1.8 8.8 0.0 3.1 1 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 VBB31046.1 - 0.072 13.0 2.2 11 6.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB31048.1 - 1.7e-19 68.8 6.9 6.9e-08 32.0 0.6 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB31048.1 - 2.5e-18 64.6 1.9 1.5e-05 24.7 0.3 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB31048.1 - 3e-18 66.1 2.5 3.5e-06 27.4 0.0 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 VBB31048.1 - 1.7e-17 62.1 2.3 0.00063 19.8 0.3 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB31048.1 - 2.1e-17 62.5 12.8 1.2e-09 37.7 0.8 4.9 2 1 3 5 5 5 3 TPR repeat TPR_16 PF13432.6 VBB31048.1 - 5.4e-13 49.3 0.9 0.0092 16.6 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 VBB31048.1 - 7.4e-12 44.7 8.6 0.00074 19.3 0.4 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 VBB31048.1 - 8.4e-12 44.9 0.3 0.054 14.3 0.1 5.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 VBB31048.1 - 2.7e-11 43.0 9.5 0.00082 19.6 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB31048.1 - 8e-10 38.9 7.1 0.0008 19.7 0.1 4.7 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 VBB31048.1 - 1.8e-07 31.1 2.3 0.038 14.6 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB31048.1 - 2.7e-07 30.1 3.3 0.13 12.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB31048.1 - 6.9e-05 22.9 0.5 0.059 13.5 0.0 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 VBB31048.1 - 0.0002 20.4 0.2 0.00048 19.2 0.2 1.5 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 VBB31048.1 - 0.0022 18.5 4.0 3 8.7 0.1 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB31048.1 - 0.0051 16.9 0.0 0.3 11.2 0.0 2.9 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 VBB31048.1 - 0.0088 16.4 4.5 6.7 7.1 0.3 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 VBB31048.1 - 0.039 13.3 1.8 0.74 9.1 0.3 2.8 1 1 2 3 3 3 0 MalT-like TPR region Pkinase PF00069.25 VBB31050.1 - 2e-50 171.6 0.0 3.3e-50 170.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31050.1 - 4.5e-20 72.0 0.0 6.7e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB31050.1 - 1.7e-07 31.4 0.7 0.00017 21.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 VBB31050.1 - 0.012 15.2 0.3 0.033 13.8 0.3 1.6 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 VBB31050.1 - 0.054 13.1 0.3 0.088 12.4 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RNA_pol_I_A49 PF06870.12 VBB31051.1 - 6.8e-43 147.0 0.0 8.7e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Bac_RepA_C PF18008.1 VBB31051.1 - 0.06 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain ERG4_ERG24 PF01222.17 VBB31052.1 - 1.5e-40 139.3 20.3 1.9e-40 139.0 20.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 VBB31052.1 - 1.3e-09 37.9 1.7 1.3e-09 37.9 1.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 VBB31052.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.8 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 VBB31052.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.9 3 0 0 3 3 3 0 Phospholipid methyltransferase Peptidase_S49_N PF08496.10 VBB31053.1 - 0.021 14.9 0.4 0.025 14.6 0.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal N6_Mtase PF02384.16 VBB31053.1 - 0.067 12.4 0.2 0.079 12.2 0.2 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase PEHE PF15275.6 VBB31053.1 - 0.076 13.6 0.5 0.11 13.1 0.5 1.2 1 0 0 1 1 1 0 PEHE domain Cytochrom_B558a PF05038.13 VBB31053.1 - 0.085 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Comm PF15957.5 VBB31053.1 - 0.1 13.0 3.0 0.39 11.1 3.0 1.8 1 1 0 1 1 1 0 Commissureless Ribosomal_L2_C PF03947.18 VBB31054.1 - 1.9e-46 157.4 2.9 3.3e-46 156.6 2.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 VBB31054.1 - 1.5e-17 63.3 0.1 4.5e-17 61.8 0.1 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain His_Phos_1 PF00300.22 VBB31055.1 - 8.1e-11 42.0 0.0 2.1e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 VBB31055.1 - 0.029 13.7 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 VBB31056.1 - 3.9e-65 219.8 0.0 5.6e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31056.1 - 2.9e-32 112.0 0.0 3.9e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 VBB31056.1 - 1.8e-09 38.1 1.0 1.8e-09 38.1 1.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 VBB31056.1 - 1.5e-05 24.4 0.0 4.3e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 VBB31056.1 - 0.00017 21.3 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 VBB31056.1 - 0.00048 19.0 0.0 0.00075 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB31056.1 - 0.0056 16.0 0.2 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB31056.1 - 0.066 12.2 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 VBB31056.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 VBB31056.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.25 VBB31057.1 - 2.4e-34 118.5 0.0 3.4e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB31057.1 - 4.2e-15 55.9 0.0 5.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB31057.1 - 0.00089 19.2 0.1 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 VBB31057.1 - 0.0082 15.6 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 VBB31057.1 - 0.068 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.22 VBB31058.1 - 8.5e-47 158.8 0.0 9.8e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB31058.1 - 1.8e-16 60.5 0.0 2.5e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB31058.1 - 5.2e-07 29.3 0.0 6.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB31058.1 - 8.1e-07 28.8 0.0 2.1e-06 27.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB31058.1 - 1.1e-05 25.4 0.0 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 VBB31058.1 - 0.00013 22.0 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsJ PF01728.19 VBB31059.1 - 4.9e-32 111.4 0.0 8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 VBB31059.1 - 2.9e-08 33.5 4.8 3.8e-08 33.1 2.7 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 VBB31059.1 - 0.0034 17.5 0.1 0.0076 16.3 0.1 1.5 1 0 0 1 1 1 1 G-patch domain KH_9 PF17904.1 VBB31060.1 - 5.8e-32 109.9 0.6 1.9e-30 105.0 0.6 2.4 2 0 0 2 2 2 1 FMRP KH0 domain KH_1 PF00013.29 VBB31060.1 - 1e-16 60.5 0.3 8.1e-10 38.4 0.2 3.2 4 0 0 4 4 4 2 KH domain Tudor_FRX1 PF18336.1 VBB31060.1 - 2.1e-10 40.3 0.0 6.3e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Fragile X mental retardation Tudor domain FXMRP1_C_core PF12235.8 VBB31060.1 - 1.4e-05 25.7 11.3 4.1e-05 24.2 11.4 1.7 1 1 0 1 1 1 1 Fragile X-related 1 protein core C terminal Agenet PF05641.12 VBB31060.1 - 9.8e-05 22.7 0.0 1.1 9.8 0.0 3.2 3 0 0 3 3 3 2 Agenet domain KH_4 PF13083.6 VBB31060.1 - 0.0016 18.2 0.4 0.64 9.9 0.4 3.1 2 1 0 2 2 2 1 KH domain Myosin_N PF02736.19 VBB31060.1 - 0.039 13.8 0.4 11 5.9 0.1 2.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain SYF2 PF08231.12 VBB31061.1 - 3e-42 144.7 8.9 3e-42 144.7 8.9 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Y_phosphatase PF00102.27 VBB31062.1 - 3.9e-36 124.8 0.3 5e-36 124.4 0.3 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CPG4 PF15481.6 VBB31063.1 - 1.6 9.4 10.0 0.28 11.8 3.0 2.6 2 2 0 2 2 2 0 Chondroitin proteoglycan 4 Y_phosphatase PF00102.27 VBB31064.1 - 1.8e-50 171.7 0.5 2.3e-38 132.1 1.3 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase VPS9 PF02204.18 VBB31066.1 - 2.9e-25 88.5 0.0 9.4e-25 86.8 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 VBB31066.1 - 9.1e-16 58.2 0.0 2.8e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF5601 PF18151.1 VBB31066.1 - 0.13 12.6 0.1 0.49 10.7 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Complex1_51K PF01512.17 VBB31067.1 - 2.9e-49 166.8 0.0 4.4e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 VBB31067.1 - 2.3e-29 101.3 0.1 4.7e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 VBB31067.1 - 1.3e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 SLBB domain Hydrolase_3 PF08282.12 VBB31068.1 - 0.00041 20.2 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 VBB31068.1 - 0.06 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase MFS_1 PF07690.16 VBB31069.1 - 4.8e-55 186.9 25.2 4.8e-55 186.9 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3188 PF11384.8 VBB31069.1 - 0.083 12.6 0.7 0.63 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) EF-hand_6 PF13405.6 VBB31070.1 - 2.3e-13 48.9 1.5 1.7e-06 27.5 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 VBB31070.1 - 6.7e-13 48.9 0.1 1.8e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB31070.1 - 1.4e-10 39.9 4.9 6.9e-06 25.2 1.5 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 VBB31070.1 - 4.4e-07 29.6 0.4 0.0048 16.7 0.1 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB31070.1 - 6.5e-05 22.2 10.5 0.00034 20.0 1.0 3.4 2 1 0 2 2 2 1 EF hand UPF0154 PF03672.13 VBB31070.1 - 0.0014 18.6 0.8 0.019 15.0 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 VBB31070.1 - 0.0033 17.7 0.5 0.0091 16.3 0.3 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 VBB31070.1 - 0.0043 17.9 0.0 3 8.8 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain POTRA PF07244.15 VBB31070.1 - 0.012 16.1 0.5 1.1 9.9 0.0 2.5 3 0 0 3 3 3 0 Surface antigen variable number repeat SurA_N_2 PF13623.6 VBB31070.1 - 0.012 15.4 0.6 0.63 9.9 0.2 2.3 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_9 PF14658.6 VBB31070.1 - 0.038 14.3 0.0 4.2 7.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Adenine_glyco PF03352.13 VBB31070.1 - 0.074 12.8 0.1 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Methyladenine glycosylase SurA_N_3 PF13624.6 VBB31070.1 - 0.095 12.5 1.3 1.4 8.7 0.7 2.1 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_1 PF00036.32 VBB31071.1 - 2e-05 23.8 0.6 0.0014 18.0 0.1 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 VBB31071.1 - 0.00013 21.6 0.1 0.0014 18.3 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 VBB31071.1 - 0.0003 21.2 1.2 0.0039 17.6 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 VBB31071.1 - 0.027 14.3 1.8 0.7 9.8 0.2 2.8 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 VBB31071.1 - 0.09 12.3 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 EF hand CRAL_TRIO_2 PF13716.6 VBB31072.1 - 5.2e-39 133.6 2.7 9.6e-37 126.2 2.7 2.5 3 0 0 3 3 3 2 Divergent CRAL/TRIO domain RhoGAP PF00620.27 VBB31072.1 - 1.2e-36 125.8 0.1 2e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 VBB31072.1 - 2.1e-08 34.0 2.4 6.2e-08 32.5 1.5 2.1 2 1 0 2 2 2 1 CRAL/TRIO domain DSPn PF14671.6 VBB31073.1 - 6.6e-41 140.1 0.0 1.8e-40 138.7 0.0 1.8 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 VBB31073.1 - 2.9e-14 53.0 0.1 1.7e-13 50.5 0.0 2.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB31073.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 VBB31073.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 VBB31073.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 VBB31073.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Fmp27_GFWDK PF10347.9 VBB31075.1 - 4.3e-29 101.6 0.0 8.3e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 VBB31075.1 - 1e-06 28.7 0.6 1.2e-05 25.3 0.6 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2405) Seryl_tRNA_N PF02403.22 VBB31075.1 - 0.67 10.2 2.8 0.58 10.4 0.9 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Dpy-30 PF05186.13 VBB31076.1 - 4.9e-20 70.9 1.3 8e-20 70.3 1.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.22 VBB31076.1 - 1.4e-08 34.4 0.2 3.7e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB31076.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif zf-CCHC PF00098.23 VBB31076.1 - 0.087 12.9 1.8 0.17 12.0 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2678 PF10856.8 VBB31078.1 - 0.57 10.1 4.2 0.32 10.9 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) CUB PF00431.20 VBB31079.1 - 1.2e-13 51.3 0.4 2.3e-13 50.5 0.4 1.5 1 0 0 1 1 1 1 CUB domain Lectin_C PF00059.21 VBB31079.1 - 1e-11 45.5 0.3 3e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain WBP-1 PF11669.8 VBB31079.1 - 0.0026 18.4 0.0 0.0084 16.7 0.0 1.9 1 0 0 1 1 1 1 WW domain-binding protein 1 CAP_C PF08603.11 VBB31079.1 - 0.043 13.4 0.2 0.12 12.0 0.2 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Shisa PF13908.6 VBB31079.1 - 0.072 13.3 0.4 0.072 13.3 0.4 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 VBB31079.1 - 0.12 12.3 0.3 0.53 10.2 0.1 2.2 2 0 0 2 2 2 0 Transmembrane 52 Ncstrn_small PF18266.1 VBB31080.1 - 1.2e-40 139.3 0.0 1.7e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 VBB31080.1 - 5.1e-35 121.0 0.5 1e-34 120.0 0.1 1.6 2 0 0 2 2 2 1 Nicastrin Peptidase_M28 PF04389.17 VBB31080.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PSI PF01437.25 VBB31083.1 - 0.21 12.2 12.1 0.36 11.4 12.1 1.4 1 0 0 1 1 1 0 Plexin repeat MGC-24 PF05283.11 VBB31083.1 - 0.33 11.4 4.8 0.53 10.7 4.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CarbpepA_inh PF02977.15 VBB31083.1 - 1.1 9.1 5.3 2.7 7.9 5.3 1.6 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Methyltransf_28 PF02636.17 VBB31084.1 - 3e-51 174.6 0.1 1.7e-50 172.1 0.1 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FARP PF01581.16 VBB31085.1 - 0.064 13.8 9.7 1.1 10.0 1.1 3.0 3 0 0 3 3 3 0 FMRFamide related peptide family COX6C PF02937.15 VBB31085.1 - 0.98 9.6 5.3 11 6.2 1.9 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIc Sec3_C PF09763.9 VBB31087.1 - 2 6.7 4.7 1.8 6.8 4.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 zf-C2H2_4 PF13894.6 VBB31088.1 - 0.00071 20.2 14.3 3.5 8.7 2.1 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Dof PF02701.15 VBB31088.1 - 0.0011 19.1 3.6 0.0013 18.8 0.5 2.6 3 0 0 3 3 3 1 Dof domain, zinc finger zf-RRPl_C4 PF17026.5 VBB31088.1 - 0.004 17.2 0.6 0.004 17.2 0.6 2.0 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type zf_C2H2_ZHX PF18387.1 VBB31088.1 - 0.042 13.5 2.8 1.4 8.6 0.1 2.8 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 VBB31088.1 - 0.055 13.8 0.3 0.055 13.8 0.3 1.8 2 0 0 2 2 2 0 zinc-finger-containing domain C1_2 PF03107.16 VBB31088.1 - 6.1 7.2 7.4 48 4.4 0.1 3.9 3 1 1 4 4 4 0 C1 domain zf-C2H2_12 PF18658.1 VBB31088.1 - 8.8 6.0 8.9 2.7 7.6 0.4 2.8 2 1 1 3 3 3 0 Zinc-finger C2H2-type Sterol-sensing PF12349.8 VBB31089.1 - 6.8e-05 22.8 3.3 6.8e-05 22.8 3.3 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 VBB31089.1 - 0.00031 19.0 44.8 0.00047 18.4 5.8 2.1 2 0 0 2 2 2 2 Patched family DM PF00751.18 VBB31090.1 - 7.4e-14 51.4 9.4 1.4e-13 50.5 9.4 1.4 1 0 0 1 1 1 1 DM DNA binding domain zf-C2H2_aberr PF17017.5 VBB31090.1 - 0.0049 17.0 0.2 0.0077 16.4 0.2 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger DGOK PF05035.12 VBB31090.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase zf-C3HC PF07967.13 VBB31090.1 - 0.074 13.1 2.9 0.29 11.2 1.3 2.3 1 1 1 2 2 2 0 C3HC zinc finger-like Pacs-1 PF10254.9 VBB31091.1 - 1.5e-41 142.8 4.1 4.2e-40 138.0 0.0 3.4 2 1 0 2 2 2 2 PACS-1 cytosolic sorting protein Neuralized PF07177.12 VBB31092.1 - 7.2e-91 302.0 0.0 3.3e-47 160.2 0.0 2.3 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 VBB31092.1 - 5e-13 48.7 10.8 1e-12 47.7 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB31092.1 - 3.6e-06 26.7 10.5 7.3e-06 25.8 10.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 VBB31092.1 - 2.7e-05 24.4 13.3 7.5e-05 23.0 13.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB31092.1 - 0.0024 17.7 13.0 0.0024 17.7 13.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB31092.1 - 0.15 12.1 13.0 0.35 10.9 13.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Methyltransf_8 PF05148.15 VBB31093.1 - 4.4e-87 291.5 1.3 8.3e-87 290.6 0.2 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase NOG1_N PF17835.1 VBB31093.1 - 5.6e-50 169.4 3.1 5.6e-50 169.4 3.1 2.6 2 0 0 2 2 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 VBB31093.1 - 3.3e-25 87.6 0.2 8e-25 86.4 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 VBB31093.1 - 6.1e-22 77.4 1.6 1.4e-21 76.2 1.6 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 VBB31093.1 - 2.1e-16 60.0 0.0 6.7e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_11 PF08241.12 VBB31093.1 - 2e-08 34.8 0.9 1.9e-07 31.6 0.0 3.2 3 1 0 3 3 2 1 Methyltransferase domain FeoB_N PF02421.18 VBB31093.1 - 1.2e-07 31.4 0.2 4.5e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Methyltransf_25 PF13649.6 VBB31093.1 - 2e-06 28.4 0.1 0.00079 20.1 0.1 3.9 2 1 0 2 2 2 1 Methyltransferase domain RsgA_GTPase PF03193.16 VBB31093.1 - 0.00031 20.7 0.1 0.27 11.1 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 VBB31093.1 - 0.0014 18.0 0.3 0.011 15.1 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.23 VBB31093.1 - 0.0023 18.0 1.9 3.5 7.7 0.0 3.8 4 0 0 4 4 4 2 Dynamin family Methyltransf_12 PF08242.12 VBB31093.1 - 0.028 15.1 0.6 8.6 7.2 0.0 4.0 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 VBB31093.1 - 0.037 13.8 4.5 0.58 9.9 0.3 3.4 2 2 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.6 VBB31093.1 - 0.058 13.7 0.2 3 8.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain MTS PF05175.14 VBB31093.1 - 0.1 12.2 0.4 2.6 7.6 0.1 2.6 1 1 1 2 2 2 0 Methyltransferase small domain AAA_16 PF13191.6 VBB31093.1 - 0.14 12.6 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Homeodomain PF00046.29 VBB31094.1 - 7.8e-21 73.7 3.1 1.4e-20 72.8 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB31094.1 - 0.009 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain RRM_1 PF00076.22 VBB31095.1 - 2e-21 75.6 0.1 1.1e-10 41.1 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 VBB31095.1 - 1.2e-12 48.0 0.0 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 VBB31095.1 - 1e-05 25.5 0.0 0.02 15.0 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 VBB31095.1 - 4.1e-05 23.6 0.0 0.00096 19.2 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB31095.1 - 0.0084 16.1 0.1 2.3 8.3 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF2283 PF10049.9 VBB31095.1 - 0.049 13.9 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Neur_chan_LBD PF02931.23 VBB31096.1 - 4.9e-08 32.7 2.2 6.6e-08 32.3 2.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain FERM_M PF00373.18 VBB31097.1 - 4.5e-22 78.7 0.1 9.8e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 VBB31097.1 - 2.8e-20 72.5 0.0 8.9e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 VBB31097.1 - 1.4e-17 63.4 0.3 6e-17 61.4 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 VBB31097.1 - 8.5e-12 45.0 9.3 1.8e-11 44.0 9.3 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) bPH_6 PF10756.9 VBB31097.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain preATP-grasp_3 PF18301.1 VBB31097.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 pre ATP-grasp 3 domain Homeodomain PF00046.29 VBB31099.1 - 1.4e-23 82.4 4.1 8.6e-23 80.0 2.9 2.3 2 0 0 2 2 2 1 Homeodomain ATP-synt PF00231.19 VBB31100.1 - 9.7e-80 268.3 5.9 1.1e-79 268.1 5.9 1.0 1 0 0 1 1 1 1 ATP synthase V-set_2 PF15910.5 VBB31101.1 - 0.037 14.1 0.4 3.7 7.7 0.0 2.3 1 1 1 2 2 2 0 ICOS V-set domain KH_1 PF00013.29 VBB31102.1 - 1.4e-34 117.7 17.1 1.4e-17 63.3 1.4 4.0 5 0 0 5 5 5 3 KH domain KH_2 PF07650.17 VBB31102.1 - 8.4e-17 60.8 11.8 2.2e-07 30.6 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 VBB31102.1 - 3e-08 33.6 5.9 0.0082 16.2 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 VBB31102.1 - 0.011 15.5 11.8 0.35 10.8 0.1 4.0 4 1 0 4 4 4 0 KH domain KRBA1 PF15287.6 VBB31102.1 - 0.26 11.0 0.4 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 KRBA1 family repeat dsrm PF00035.26 VBB31103.1 - 2e-38 130.9 2.9 6.5e-09 36.4 0.0 4.9 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.7 VBB31103.1 - 0.00011 22.4 5.7 1.4 9.2 0.0 4.9 4 1 0 4 4 4 3 double strand RNA binding domain from DEAD END PROTEIN 1 IRK_C PF17655.1 VBB31103.1 - 0.035 13.7 0.1 0.087 12.4 0.1 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain LPP20 PF02169.16 VBB31103.1 - 0.088 13.2 4.8 2.6 8.5 0.1 3.3 3 0 0 3 3 3 0 LPP20 lipoprotein PH PF00169.29 VBB31104.1 - 0.0036 17.8 0.0 0.0038 17.7 0.0 1.2 1 0 0 1 1 1 1 PH domain CDP-OH_P_transf PF01066.21 VBB31105.1 - 7.9e-07 29.8 0.0 7.9e-07 29.8 0.0 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Sema PF01403.19 VBB31106.1 - 3.4e-104 349.0 0.0 4.2e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 VBB31106.1 - 0.0002 21.8 6.6 0.00044 20.7 6.6 1.6 1 0 0 1 1 1 1 Plexin repeat Pkinase PF00069.25 VBB31107.1 - 2.7e-73 246.6 0.0 4e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31107.1 - 5.9e-34 117.5 0.0 9.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 VBB31107.1 - 1.8e-22 78.9 23.0 1.9e-12 46.9 3.6 3.4 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB31107.1 - 6.9e-07 29.5 11.9 0.00018 21.8 1.7 2.6 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 VBB31107.1 - 2.7e-06 26.9 0.0 5.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB31107.1 - 4.8e-05 22.8 0.0 7.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.16 VBB31107.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family PHD_2 PF13831.6 VBB31107.1 - 0.0059 16.1 10.0 0.14 11.7 1.6 3.2 3 0 0 3 3 3 2 PHD-finger Spike_torovirin PF17072.5 VBB31107.1 - 0.0069 13.6 0.0 0.0095 13.1 0.0 1.1 1 0 0 1 1 1 1 Torovirinae spike glycoprotein FYVE_2 PF02318.16 VBB31107.1 - 0.046 13.9 12.2 0.41 10.9 1.3 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 VBB31107.1 - 0.058 13.3 19.0 0.49 10.3 4.2 2.7 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 VBB31107.1 - 1.7 9.0 24.7 0.096 13.0 3.5 3.3 3 0 0 3 3 3 0 RING-like domain Prok-RING_1 PF14446.6 VBB31107.1 - 2.2 8.3 14.4 4.9 7.2 2.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FUSC-like PF12805.7 VBB31108.1 - 0.0048 16.0 0.0 0.0055 15.8 0.0 1.1 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS ERM PF00769.19 VBB31108.1 - 0.022 14.6 0.9 0.028 14.3 0.7 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Hist_deacetyl PF00850.19 VBB31109.1 - 2.3e-79 267.1 0.0 3e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Raftlin PF15250.6 VBB31109.1 - 0.1 11.3 1.3 0.15 10.8 1.3 1.2 1 0 0 1 1 1 0 Raftlin Diphthamide_syn PF01866.17 VBB31110.1 - 2.9e-69 233.9 0.0 3.5e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Metallophos_2 PF12850.7 VBB31110.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.31 VBB31111.1 - 1.7e-24 86.1 0.5 8e-23 80.8 0.2 2.2 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 VBB31111.1 - 8.1e-12 45.2 0.8 1.4e-10 41.2 0.1 2.8 2 1 0 2 2 2 1 BTB And C-terminal Kelch Dcc1 PF09724.9 VBB31112.1 - 3.5e-20 72.6 0.1 4.1e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 zf-C4 PF00105.18 VBB31115.1 - 2.1e-26 92.2 15.5 4.1e-26 91.2 15.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB31115.1 - 3.1e-25 89.0 0.0 6.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor M11L PF11099.8 VBB31115.1 - 0.14 12.4 3.6 0.83 9.9 0.6 2.5 2 0 0 2 2 2 0 Apoptosis regulator M11L like zf-HC5HC2H PF13771.6 VBB31115.1 - 4.6 7.6 9.2 5.4 7.3 7.7 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain PWWP PF00855.17 VBB31116.1 - 1e-16 61.1 0.0 3.1e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 PWWP domain Syntaxin_2 PF14523.6 VBB31117.1 - 2.1e-16 60.1 0.3 2.1e-16 60.1 0.3 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 VBB31117.1 - 0.016 15.2 0.5 0.016 15.2 0.5 2.7 3 0 0 3 3 3 0 SNARE domain TMF_TATA_bd PF12325.8 VBB31117.1 - 0.058 13.6 21.2 0.14 12.4 13.9 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin PF00804.25 VBB31117.1 - 0.11 12.1 21.1 0.76 9.4 21.1 2.5 1 1 0 1 1 1 0 Syntaxin Pinin_SDK_memA PF04696.13 VBB31117.1 - 0.12 12.4 14.0 0.097 12.7 12.5 1.6 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4638 PF15472.6 VBB31117.1 - 0.19 11.5 8.8 0.21 11.3 7.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) MCPsignal PF00015.21 VBB31117.1 - 0.25 11.1 15.5 0.17 11.7 11.8 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain THOC7 PF05615.13 VBB31117.1 - 0.34 11.2 13.1 0.53 10.6 12.0 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 MID_MedPIWI PF18296.1 VBB31117.1 - 0.52 10.0 6.7 1.3 8.8 6.1 1.7 1 1 1 2 2 2 0 MID domain of medPIWI FUSC PF04632.12 VBB31117.1 - 0.6 8.6 9.0 0.72 8.3 9.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.6 VBB31117.1 - 1.1 7.8 14.0 3.6 6.1 14.2 1.6 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 VBB31117.1 - 1.7 8.1 13.5 2.3 7.7 13.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 VBB31117.1 - 2.1 7.2 22.5 1.8 7.3 18.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.16 VBB31117.1 - 2.6 6.8 4.7 3 6.6 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 VBB31117.1 - 2.7 8.0 18.4 4.4 7.4 13.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 VBB31117.1 - 3 8.2 16.3 4.5 7.6 0.5 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 VBB31117.1 - 3.8 6.7 16.6 2.6 7.2 5.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 VBB31117.1 - 4.8 7.7 20.3 8.4 6.9 15.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Lectin_N PF03954.14 VBB31117.1 - 6.4 6.5 14.4 1 9.1 6.4 2.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Neur_chan_memb PF02932.16 VBB31117.1 - 8.7 6.3 7.1 12 5.9 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FdhE PF04216.12 VBB31117.1 - 9.1 6.1 13.5 8.1 6.2 11.9 1.6 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation NIF PF03031.18 VBB31118.1 - 3.2e-24 85.5 0.2 6.7e-24 84.4 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 VBB31118.1 - 3.1e-10 40.3 0.1 1.8e-09 37.9 0.0 2.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 VBB31118.1 - 2.5e-08 33.7 0.2 8.8e-08 32.0 0.2 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 VBB31118.1 - 0.00011 22.6 0.1 0.00037 20.9 0.1 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 VBB31118.1 - 0.00018 21.7 0.2 0.00055 20.2 0.2 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Tom37 PF10568.9 VBB31119.1 - 5.7e-23 81.6 0.4 9.8e-23 80.8 0.1 1.5 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 VBB31119.1 - 1.4e-11 45.0 0.1 3e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 VBB31119.1 - 0.032 14.0 0.2 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RhoGAP PF00620.27 VBB31120.1 - 6.9e-21 74.7 0.0 1.2e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Ras_bdg_2 PF14847.6 VBB31120.1 - 0.099 13.0 0.0 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Ras-binding domain of Byr2 FGGY_C PF02782.16 VBB31122.1 - 1.4e-12 47.7 0.2 1.8e-12 47.4 0.2 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CDC37_M PF08565.11 VBB31123.1 - 0.047 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain Abdominal-A PF12407.8 VBB31123.1 - 0.37 10.4 1.4 0.56 9.8 1.4 1.2 1 0 0 1 1 1 0 Homeobox protein Pkinase_Tyr PF07714.17 VBB31124.1 - 2.9e-75 252.9 0.0 5.2e-75 252.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB31124.1 - 7e-36 123.9 0.0 1.4e-35 123.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 VBB31124.1 - 2.9e-23 81.8 0.0 5.7e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 VBB31124.1 - 0.043 13.1 0.1 0.13 11.5 0.1 1.8 1 1 1 2 2 2 0 Kinase-like NHL PF01436.21 VBB31124.1 - 0.087 12.9 0.2 0.41 10.8 0.1 2.2 2 0 0 2 2 2 0 NHL repeat Pkinase_fungal PF17667.1 VBB31124.1 - 0.09 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PNRC PF15365.6 VBB31127.1 - 2.9e-05 23.7 0.9 2.9e-05 23.7 0.9 2.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Tis11B_N PF04553.12 VBB31128.1 - 0.056 14.0 0.3 0.13 12.8 0.3 1.6 1 0 0 1 1 1 0 Tis11B like protein, N terminus zf-Di19 PF05605.12 VBB31128.1 - 0.11 12.7 0.6 0.97 9.8 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 VBB31128.1 - 0.49 11.1 9.4 2.2 9.0 0.3 3.5 2 1 0 2 2 2 0 FOXP coiled-coil domain NOT2_3_5 PF04153.18 VBB31129.1 - 1.4e-22 80.2 0.8 1.8e-22 79.9 0.8 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Patched PF02460.18 VBB31130.1 - 4.4e-63 213.6 13.2 6.1e-62 209.8 10.5 2.3 1 1 1 2 2 2 1 Patched family Sterol-sensing PF12349.8 VBB31130.1 - 1e-26 93.6 3.5 1e-26 93.6 3.5 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 VBB31130.1 - 5.6e-08 32.1 9.3 2.8e-07 29.8 3.6 2.2 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 VBB31130.1 - 0.08 10.6 13.5 0.11 10.2 13.5 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Beach PF02138.18 VBB31132.1 - 8.4e-114 379.6 2.1 1.3e-111 372.4 2.1 2.2 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 VBB31132.1 - 2.3e-16 59.7 0.0 5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 VBB31132.1 - 1.5e-11 44.6 2.3 0.004 18.0 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31132.1 - 0.00047 20.4 0.1 0.022 15.1 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 VBB31132.1 - 0.0039 17.2 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 VBB31132.1 - 0.1 11.1 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Mab-21 PF03281.14 VBB31133.1 - 1.1e-89 300.7 0.0 1.6e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein DUF1088 PF06469.11 VBB31134.1 - 8.6e-57 191.5 3.6 1.3e-56 190.8 3.6 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 VBB31134.1 - 0.0013 18.8 0.0 0.0042 17.2 0.0 1.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 VBB31134.1 - 0.011 15.0 1.3 0.017 14.4 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4800) GRAM PF02893.20 VBB31134.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 GRAM domain MethyTransf_Reg PF10119.9 VBB31134.1 - 0.24 12.1 2.5 3 8.6 1.9 2.9 1 1 2 3 3 3 0 Predicted methyltransferase regulatory domain TB2_DP1_HVA22 PF03134.19 VBB31135.1 - 7.5e-19 67.4 3.1 2e-18 66.1 3.1 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family CC PF04942.14 VBB31135.1 - 0.0014 18.8 11.0 0.0025 18.0 11.0 1.4 1 0 0 1 1 1 1 CC domain Lustrin_cystein PF14625.6 VBB31135.1 - 6.5 7.2 10.4 11 6.5 10.4 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain KH_1 PF00013.29 VBB31136.1 - 2.9e-36 123.1 7.9 3e-12 46.2 0.4 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 VBB31136.1 - 2.2e-10 40.2 7.2 7.3e-05 22.5 1.1 3.3 2 1 1 3 3 3 2 KH domain KH_4 PF13083.6 VBB31136.1 - 8.8e-06 25.5 2.2 0.021 14.7 0.0 3.8 4 0 0 4 4 4 2 KH domain KH_5 PF13184.6 VBB31136.1 - 0.0007 19.6 3.2 0.12 12.4 0.1 3.1 3 0 0 3 3 3 2 NusA-like KH domain Vps16_C PF04840.12 VBB31137.1 - 7.7e-26 90.9 5.1 7.7e-26 90.9 5.1 1.7 2 0 0 2 2 2 1 Vps16, C-terminal region Clathrin PF00637.20 VBB31137.1 - 0.015 15.1 1.6 0.034 14.0 0.3 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS SecY PF00344.20 VBB31138.1 - 1.8e-75 254.1 11.1 1.8e-75 254.1 11.1 1.8 2 0 0 2 2 2 1 SecY translocase MBOAT PF03062.19 VBB31138.1 - 1.9e-12 47.2 10.9 5.3e-12 45.8 10.9 1.8 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Plug_translocon PF10559.9 VBB31138.1 - 1.1e-08 34.7 1.2 1.1e-08 34.7 1.2 2.9 3 1 0 3 3 3 1 Plug domain of Sec61p eIF_4EBP PF05456.11 VBB31140.1 - 0.0033 17.3 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) zf-3CxxC_2 PF17180.4 VBB31141.1 - 1.5e-15 57.7 2.7 1.5e-15 57.7 2.7 1.8 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 VBB31141.1 - 1.8e-08 34.0 6.7 1.8e-08 34.0 6.7 2.0 2 0 0 2 2 2 1 Zinc knuckle UPF0515 PF15135.6 VBB31141.1 - 7.7e-06 25.5 3.2 1.2e-05 24.8 3.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-C2H2_11 PF16622.5 VBB31141.1 - 0.0047 16.7 0.4 0.0047 16.7 0.4 3.3 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-3CxxC PF13695.6 VBB31141.1 - 0.023 15.2 7.4 0.023 15.2 7.4 2.3 2 1 0 2 2 2 0 Zinc-binding domain zf-CCHC PF00098.23 VBB31141.1 - 0.061 13.4 2.2 0.061 13.4 2.2 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF1451 PF07295.11 VBB31141.1 - 0.24 11.4 2.7 0.95 9.5 2.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain Cytochrom_c3_2 PF14537.6 VBB31141.1 - 4.6 7.8 11.8 0.5 10.9 6.1 2.1 1 1 2 3 3 3 0 Cytochrome c3 zf-C2H2_4 PF13894.6 VBB31141.1 - 8 7.6 7.9 7.6 7.7 0.3 3.4 2 1 0 2 2 2 0 C2H2-type zinc finger Sulfate_transp PF00916.20 VBB31142.1 - 1.5e-66 224.7 23.8 2.8e-34 118.5 9.2 2.1 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 VBB31142.1 - 5.7e-21 74.3 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain TraL PF07178.11 VBB31142.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.9 4 2 1 6 6 6 0 TraL protein GDNF PF02351.16 VBB31143.1 - 0.0019 19.1 14.7 0.0019 19.1 14.7 2.2 2 0 0 2 2 2 1 GDNF/GAS1 domain PL48 PF15903.5 VBB31144.1 - 2.9e-35 121.9 0.9 5.3e-35 121.0 0.9 1.4 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 VBB31144.1 - 6.6e-06 26.4 0.1 4.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 VBB31144.1 - 0.05 13.9 0.1 16 6.1 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat NPH3 PF03000.14 VBB31144.1 - 0.069 12.8 0.5 0.53 9.9 0.1 2.4 2 0 0 2 2 2 0 NPH3 family hDGE_amylase PF14701.6 VBB31144.1 - 0.1 11.7 1.1 0.57 9.2 0.1 2.2 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain HEAT_EZ PF13513.6 VBB31144.1 - 0.13 12.8 0.0 1.8 9.1 0.0 2.9 3 0 0 3 3 3 0 HEAT-like repeat TPP_enzyme_N PF02776.18 VBB31145.1 - 7.6e-48 162.4 1.8 2e-47 161.0 1.9 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 VBB31145.1 - 3.1e-25 88.8 0.0 3.6e-23 82.1 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 VBB31145.1 - 8.8e-16 57.9 0.0 2.3e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain La PF05383.17 VBB31146.1 - 1e-20 73.5 0.5 2e-20 72.6 0.5 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 VBB31146.1 - 0.089 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CUB PF00431.20 VBB31147.1 - 6.2e-34 116.6 11.6 6.5e-14 52.2 1.9 5.1 4 1 0 4 4 4 4 CUB domain VanY PF02557.17 VBB31147.1 - 0.13 12.1 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase EB PF01683.18 VBB31148.1 - 0.19 12.1 40.8 0.54 10.6 14.1 4.2 2 2 2 4 4 4 0 EB module PRK PF00485.18 VBB31149.1 - 8.8e-49 165.9 0.1 1.4e-48 165.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 VBB31149.1 - 3.2e-06 26.9 0.1 0.078 12.7 0.0 2.4 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 VBB31149.1 - 9.8e-05 22.9 0.1 0.00022 21.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 VBB31149.1 - 0.00013 21.4 0.0 0.00031 20.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Evr1_Alr PF04777.13 VBB31149.1 - 0.00052 20.4 1.1 0.0013 19.2 0.0 2.2 3 0 0 3 3 3 1 Erv1 / Alr family AAA_33 PF13671.6 VBB31149.1 - 0.0033 17.6 0.0 0.0095 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 VBB31149.1 - 0.01 15.6 2.4 0.47 10.2 0.1 2.6 2 1 0 3 3 3 0 Cytidylate kinase CPT PF07931.12 VBB31149.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 VBB31149.1 - 0.03 14.8 3.1 0.8 10.1 3.1 2.4 1 1 0 1 1 1 0 AAA domain DNA_primase_S PF01896.19 VBB31149.1 - 0.036 14.1 0.0 0.54 10.3 0.0 2.1 1 1 0 1 1 1 0 DNA primase small subunit T2SSE PF00437.20 VBB31149.1 - 0.057 12.5 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_L7Ae PF01248.26 VBB31150.1 - 3.6e-25 87.5 0.0 4.2e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 VBB31150.1 - 0.021 14.9 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Galactosyl_T PF01762.21 VBB31151.1 - 2.5e-27 96.0 0.0 3.3e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Glycos_transf_1 PF00534.20 VBB31152.1 - 4.7e-21 75.1 0.0 7.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 VBB31152.1 - 8.1e-14 52.0 0.1 2.3e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 VBB31152.1 - 9.6e-11 42.2 0.0 1.7e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 VBB31152.1 - 1.1e-06 29.2 0.0 2.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 VBB31152.1 - 0.046 13.8 0.2 7.1 6.6 0.0 2.7 2 1 1 3 3 3 0 ALG11 mannosyltransferase N-terminus Glyco_trans_4_3 PF12000.8 VBB31152.1 - 0.086 12.5 0.1 0.3 10.8 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 4 group Sod_Cu PF00080.20 VBB31153.1 - 6.2e-06 26.4 0.0 7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MFS_1 PF07690.16 VBB31154.1 - 0.00019 20.5 46.3 0.0003 19.8 22.8 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Transport_MerF PF11431.8 VBB31154.1 - 3.6 7.5 8.8 0.26 11.2 2.9 2.3 2 0 0 2 2 2 0 Membrane transport protein MerF Metallophos PF00149.28 VBB31155.1 - 1.1e-40 140.3 0.1 1.4e-40 140.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB31155.1 - 1.4e-22 79.8 0.3 3.2e-22 78.7 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 VBB31157.1 - 3.5e-91 305.2 0.7 1.4e-69 234.4 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31157.1 - 7.3e-51 172.9 0.0 1.4e-37 129.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 VBB31157.1 - 1.5e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 VBB31157.1 - 1.6e-05 25.5 0.5 4.5e-05 24.1 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 VBB31157.1 - 0.0043 16.1 0.0 0.0087 15.0 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 VBB31157.1 - 0.006 15.9 0.0 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB31157.1 - 0.027 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Laminin_G_2 PF02210.24 VBB31158.1 - 2.6e-28 99.1 0.0 1e-22 81.1 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.17 VBB31158.1 - 1.1e-22 80.9 0.1 1.8e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_1 PF00054.23 VBB31158.1 - 8.6e-21 74.5 0.0 7.5e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain EGF PF00008.27 VBB31158.1 - 1.1e-06 28.8 33.4 0.0024 18.1 2.9 4.4 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 VBB31158.1 - 0.00011 22.7 31.7 0.01 16.4 2.0 4.9 4 0 0 4 4 4 3 Human growth factor-like EGF RasGEF PF00617.19 VBB31159.1 - 1.1e-12 48.5 0.7 1.1e-12 48.5 0.7 2.7 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 VBB31159.1 - 1.7e-10 41.0 2.4 4.9e-10 39.6 0.2 2.9 2 0 0 2 2 2 1 RasGEF N-terminal motif AAA PF00004.29 VBB31159.1 - 1.7 9.1 4.1 7.6 7.0 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RasGEF PF00617.19 VBB31160.1 - 6e-22 78.7 0.0 5.3e-21 75.6 0.0 1.9 1 1 1 2 2 2 1 RasGEF domain MFS_2 PF13347.6 VBB31161.1 - 1.5e-16 60.0 13.0 1.5e-16 60.0 13.0 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein STIMATE PF12400.8 VBB31161.1 - 1.5 9.4 8.7 0.5 10.9 0.3 3.5 2 2 1 3 3 3 0 STIMATE family AHD PF17793.1 VBB31162.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 ANC1 homology domain (AHD) wnt PF00110.19 VBB31163.1 - 3.7e-106 355.2 26.9 4.3e-106 355.0 26.9 1.0 1 0 0 1 1 1 1 wnt family Glyco_transf_43 PF03360.16 VBB31164.1 - 2.7e-55 187.4 0.0 3.2e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 EF-hand_13 PF17958.1 VBB31166.1 - 8.6e-36 121.6 0.0 3.3e-35 119.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 VBB31166.1 - 1.1e-17 64.2 3.2 2.6e-14 53.4 0.1 4.4 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB31166.1 - 0.00044 19.6 0.1 0.013 15.0 0.0 3.1 3 0 0 3 3 3 1 EF hand DUF4187 PF13821.6 VBB31166.1 - 0.044 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) EF-hand_6 PF13405.6 VBB31166.1 - 0.047 13.6 3.9 0.46 10.5 0.0 4.3 6 0 0 6 6 6 0 EF-hand domain EF-hand_1 PF00036.32 VBB31166.1 - 0.056 13.0 0.8 0.59 9.8 0.0 3.2 3 0 0 3 3 3 0 EF hand Herpes_UL73 PF03554.13 VBB31166.1 - 0.16 12.0 1.7 1.2 9.1 0.2 2.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein LSM PF01423.22 VBB31167.1 - 5.5e-22 77.2 0.4 6.2e-22 77.1 0.4 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 VBB31167.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Reeler PF02014.16 VBB31169.1 - 4.1e-16 59.9 0.2 8.2e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 Reeler domain Haspin_kinase PF12330.8 VBB31170.1 - 2.5e-47 161.6 2.0 5.5e-47 160.5 0.4 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase PF00069.25 VBB31170.1 - 1.7e-07 30.9 0.1 3e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31170.1 - 0.00048 19.5 0.1 0.0075 15.6 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M28 PF04389.17 VBB31171.1 - 7.4e-46 156.3 0.0 1e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 VBB31171.1 - 0.0087 15.8 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 VBB31171.1 - 0.21 10.6 0.0 0.89 8.5 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Vps51 PF08700.11 VBB31173.1 - 4.9e-08 32.9 0.9 2.2e-07 30.8 0.9 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Zw10 PF06248.13 VBB31173.1 - 0.013 14.1 6.9 0.027 13.0 0.4 3.0 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 PhoU PF01895.19 VBB31173.1 - 1.4 9.4 4.9 2.1 8.8 0.4 3.4 3 1 0 3 3 3 0 PhoU domain PITH PF06201.13 VBB31174.1 - 7.7e-38 130.1 0.1 1.4e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 VBB31174.1 - 1.5e-24 86.0 0.0 2.6e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 VBB31174.1 - 9.3e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 VBB31174.1 - 3.2e-06 27.5 0.1 1.2e-05 25.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 VBB31174.1 - 0.00012 22.0 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 VBB31174.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 VBB31174.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Sad1_UNC PF07738.13 VBB31174.1 - 0.0083 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Redoxin PF08534.10 VBB31174.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 VBB31174.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin SH3_9 PF14604.6 VBB31175.1 - 8e-26 89.6 0.1 4.7e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 VBB31175.1 - 7.4e-21 73.5 0.0 3.7e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 VBB31175.1 - 4.3e-15 55.1 0.0 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain Str_synth PF03088.16 VBB31176.1 - 3.7e-19 68.6 0.0 1.5e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 VBB31176.1 - 1.3e-10 41.3 0.0 3.6e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 VBB31176.1 - 0.027 14.7 0.0 0.63 10.3 0.0 2.8 3 0 0 3 3 3 0 Arylesterase AP-5_subunit_s1 PF15001.6 VBB31176.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 ODR4-like PF14778.6 VBB31177.1 - 2.1e-61 207.9 0.0 3.2e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Olfactory receptor 4-like zf-C3HC4_3 PF13920.6 VBB31177.1 - 4.2e-11 42.5 5.6 4.2e-11 42.5 5.6 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB31177.1 - 5.7e-09 35.7 4.3 5.7e-09 35.7 4.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 VBB31177.1 - 6.1e-09 36.1 7.5 2.3e-08 34.3 7.5 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 VBB31177.1 - 2.7e-08 33.6 8.1 9.1e-08 31.8 8.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB31177.1 - 3.4e-08 33.4 7.7 5.5e-08 32.7 4.5 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 VBB31177.1 - 4.1e-08 33.0 7.0 1.3e-07 31.5 7.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB31177.1 - 1.8e-07 30.9 6.7 4.8e-07 29.5 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB31177.1 - 3.3e-06 27.2 7.8 8.9e-06 25.8 7.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 VBB31177.1 - 3.6e-06 27.2 5.1 9.8e-06 25.8 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 VBB31177.1 - 0.028 14.5 3.2 0.088 12.9 3.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger BTB_2 PF02214.22 VBB31177.1 - 0.035 14.5 0.2 0.08 13.3 0.2 1.6 1 0 0 1 1 1 0 BTB/POZ domain Rtf2 PF04641.12 VBB31177.1 - 0.24 10.7 4.9 0.53 9.6 4.9 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 VBB31177.1 - 0.57 10.0 7.6 1.5 8.7 5.0 2.7 2 0 0 2 2 2 0 RING-like zinc finger PK PF00224.21 VBB31178.1 - 2.4e-130 434.5 2.3 2.7e-130 434.3 2.3 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 VBB31178.1 - 1.6e-07 30.7 0.3 3.3e-07 29.7 0.2 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 VBB31178.1 - 0.023 13.7 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Mfa_like_2 PF15415.6 VBB31178.1 - 0.036 13.0 0.1 0.11 11.3 0.0 1.8 3 0 0 3 3 3 0 Fimbrillin-like DEAD PF00270.29 VBB31180.1 - 2.1e-37 128.6 0.1 2.5e-37 128.3 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB31180.1 - 2.4e-10 40.7 0.0 2.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 VBB31180.1 - 0.0061 15.4 0.0 0.0078 15.1 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_11 PF13086.6 VBB31180.1 - 0.0062 16.4 0.0 1.1 9.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 VBB31180.1 - 0.0069 16.7 0.4 0.063 13.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 VBB31180.1 - 0.007 16.1 0.0 0.0089 15.7 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 VBB31180.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 VBB31180.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 VBB31180.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SecA_DEAD PF07517.14 VBB31180.1 - 0.14 11.4 0.0 0.47 9.7 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain UL42 PF17638.2 VBB31181.1 - 0.0075 16.2 0.0 0.0092 16.0 0.0 1.1 1 0 0 1 1 1 1 HCMV UL42 Tom7 PF08038.12 VBB31182.1 - 2.5e-08 33.4 0.1 4.9e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 TOM7 family GYF PF02213.16 VBB31182.1 - 8.8e-06 25.3 0.1 2.1e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 VBB31182.1 - 0.049 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 GYF domain 2 NTP_transf_9 PF04248.12 VBB31182.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Arf PF00025.21 VBB31183.1 - 4.6e-76 254.1 0.1 5.1e-76 254.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB31183.1 - 3.1e-14 53.2 0.0 4.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 VBB31183.1 - 1.1e-13 51.0 0.0 1.4e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 VBB31183.1 - 8e-13 48.3 0.0 8.5e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 VBB31183.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 VBB31183.1 - 3e-10 39.8 1.2 1.1e-07 31.3 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 VBB31183.1 - 1.8e-05 24.8 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 VBB31183.1 - 0.011 15.0 0.3 0.079 12.3 0.1 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase cobW PF02492.19 VBB31183.1 - 0.17 11.5 0.2 1.3 8.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Destabilase PF05497.12 VBB31185.1 - 6.6e-22 78.1 14.7 7.5e-22 77.9 14.7 1.0 1 0 0 1 1 1 1 Destabilase CSN8_PSD8_EIF3K PF10075.9 VBB31186.1 - 4.4e-06 26.7 0.6 7.1e-06 26.1 0.6 1.4 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family FAD_binding_9 PF08021.11 VBB31186.1 - 0.094 12.9 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain zf-ANAPC11 PF12861.7 VBB31187.1 - 1.9e-29 101.5 10.6 3.2e-29 100.8 10.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 VBB31187.1 - 1.2e-20 73.5 16.2 2.1e-20 72.8 16.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 VBB31187.1 - 5e-05 23.6 19.1 0.00036 20.8 19.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 VBB31187.1 - 0.0048 16.7 14.0 0.011 15.6 14.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB31187.1 - 0.45 10.5 15.0 1.2 9.2 15.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB31187.1 - 2.7 7.9 15.1 1.5 8.7 10.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 VBB31187.1 - 2.9 7.7 13.2 16 5.3 13.2 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 VBB31187.1 - 3.4 8.1 11.1 6.9 7.1 11.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 VBB31187.1 - 7 6.6 17.5 36 4.3 17.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 VBB31189.1 - 7e-17 61.8 0.4 1.4e-05 25.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB31189.1 - 5e-16 58.8 0.3 4e-07 30.5 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB31189.1 - 7.1e-15 53.6 0.8 0.0025 18.1 0.0 6.4 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 VBB31189.1 - 5.4e-14 51.9 1.0 0.00073 19.9 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 VBB31189.1 - 6.1e-12 45.5 6.1 1.4e-06 28.5 0.0 4.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Neur_chan_LBD PF02931.23 VBB31190.1 - 1.2e-44 152.4 1.3 1.7e-44 151.8 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB31190.1 - 0.35 10.9 3.6 0.26 11.3 2.0 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 VBB31191.1 - 1.7e-16 60.3 7.3 1.6e-08 34.0 2.2 3.1 2 1 1 3 3 3 3 Solute carrier family 12 AA_permease PF00324.21 VBB31191.1 - 6.8e-06 24.9 45.1 5.3e-05 22.0 26.9 2.2 1 1 1 2 2 2 2 Amino acid permease Mannosyl_trans PF05007.13 VBB31192.1 - 1.2e-67 228.5 16.6 1.9e-67 227.9 16.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) TP_methylase PF00590.20 VBB31192.1 - 1.6e-19 70.7 0.0 2.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PIG-U PF06728.13 VBB31192.1 - 7.6e-14 51.6 23.2 1e-13 51.1 23.2 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 VBB31192.1 - 0.0024 17.6 10.1 0.0053 16.5 10.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 87 Guanylate_cyc PF00211.20 VBB31193.1 - 5.5e-51 172.8 0.0 1.3e-50 171.5 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 VBB31193.1 - 6.1e-17 61.8 0.0 4.8e-16 58.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 VBB31193.1 - 1.3e-15 57.5 0.0 3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 VBB31193.1 - 0.0071 15.8 1.4 0.013 14.9 1.4 1.4 1 0 0 1 1 1 1 Heme NO binding associated JMY PF15871.5 VBB31193.1 - 0.02 14.2 0.1 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Junction-mediating and -regulatory protein AdoMet_Synthase PF01941.19 VBB31193.1 - 0.19 10.5 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) CBS PF00571.28 VBB31194.1 - 2.2e-18 66.5 0.4 0.0001 22.7 0.0 4.3 4 0 0 4 4 4 4 CBS domain CENP-F_leu_zip PF10473.9 VBB31195.1 - 0.0001 22.4 19.1 0.0001 22.4 19.1 6.0 1 1 4 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 VBB31195.1 - 0.0019 17.9 12.0 0.0019 17.9 12.0 3.6 1 1 2 3 3 3 1 Intermediate filament protein ATG16 PF08614.11 VBB31195.1 - 0.0057 16.9 14.7 0.0057 16.9 14.7 5.0 1 1 2 4 4 4 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 VBB31195.1 - 0.0058 16.8 13.8 0.0058 16.8 13.8 5.9 1 1 5 6 6 6 3 TATA element modulatory factor 1 TATA binding Bap31_Bap29_C PF18035.1 VBB31195.1 - 0.013 15.5 1.0 0.013 15.5 1.0 7.7 5 3 1 6 6 6 0 Bap31/Bap29 cytoplasmic coiled-coil domain TPR_MLP1_2 PF07926.12 VBB31195.1 - 0.02 14.9 12.3 0.02 14.9 12.3 6.5 1 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein NAD_binding_5 PF07994.12 VBB31195.1 - 1.4 8.2 8.0 0.17 11.3 2.3 2.4 1 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase DUF3800 PF12686.7 VBB31195.1 - 8.2 7.1 9.8 2.4e+03 -0.9 9.8 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Forkhead PF00250.18 VBB31197.1 - 2e-18 66.4 0.0 3.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain NOT2_3_5 PF04153.18 VBB31199.1 - 8.7e-27 93.8 3.0 1.1e-26 93.4 1.3 2.0 2 1 1 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF4141 PF13605.6 VBB31200.1 - 1.5 8.1 4.1 12 5.2 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4141) RasGAP PF00616.19 VBB31201.1 - 1.4e-23 83.7 5.2 1.2e-14 54.5 0.2 3.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase DivIC PF04977.15 VBB31201.1 - 0.35 10.6 4.5 1.1 9.0 4.5 1.8 1 0 0 1 1 1 0 Septum formation initiator PBP1_TM PF14812.6 VBB31201.1 - 0.43 11.0 13.7 2.4 8.6 9.1 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM192 PF14802.6 VBB31201.1 - 0.5 9.4 1.7 0.77 8.8 1.7 1.2 1 0 0 1 1 1 0 TMEM192 family DNA_pol_phi PF04931.13 VBB31201.1 - 0.72 7.9 10.2 15 3.5 10.3 2.2 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 VBB31201.1 - 1 8.6 16.3 11 5.2 14.5 2.3 2 0 0 2 2 2 0 NOA36 protein Chromo PF00385.24 VBB31202.1 - 0.0018 18.2 0.1 0.0051 16.7 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ustilago_mating PF05722.12 VBB31203.1 - 0.055 13.0 0.5 0.061 12.9 0.5 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein PARP PF00644.20 VBB31204.1 - 1.9e-66 223.4 0.7 3.6e-66 222.5 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 VBB31204.1 - 3.7e-40 137.2 0.8 1.1e-39 135.6 0.8 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 VBB31204.1 - 1.9e-32 112.0 8.1 1.5e-16 61.0 0.4 3.1 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 VBB31204.1 - 7.3e-20 70.8 3.5 2e-19 69.4 3.5 1.8 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 VBB31204.1 - 3.9e-17 61.8 4.7 3.9e-17 61.8 4.7 2.6 3 0 0 3 3 3 1 PADR1 (NUC008) domain LIM PF00412.22 VBB31204.1 - 0.17 12.1 3.7 0.47 10.7 1.0 2.8 2 0 0 2 2 2 0 LIM domain Adaptin_binding PF10199.9 VBB31204.1 - 3.8 8.1 7.0 2.9 8.5 4.4 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Aha1_N PF09229.11 VBB31205.1 - 3.5e-34 117.9 0.2 7.3e-34 116.9 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 VBB31205.1 - 1.1e-16 61.2 0.1 2.2e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 VBB31205.1 - 0.0091 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HlyIII PF03006.20 VBB31206.1 - 1.7e-68 230.7 19.6 2.3e-68 230.3 19.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related PP-binding PF00550.25 VBB31206.1 - 1.3e-11 44.7 0.2 2.6e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 VBB31206.1 - 0.067 13.4 0.4 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 Acyl-carrier LRR_8 PF13855.6 VBB31207.1 - 6.9e-73 240.3 42.8 1.6e-17 63.0 5.2 7.0 4 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 VBB31207.1 - 1.7e-38 130.0 39.7 1.7e-05 25.1 2.8 10.3 6 3 3 9 9 9 8 Leucine Rich repeats (2 copies) I-set PF07679.16 VBB31207.1 - 2e-37 127.2 0.0 3.8e-17 62.1 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB31207.1 - 5.6e-33 113.4 0.0 3.8e-15 56.3 0.0 3.9 4 0 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB31207.1 - 4.5e-24 84.6 0.0 2.6e-09 37.3 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 VBB31207.1 - 5.1e-22 78.2 0.0 1.8e-07 31.2 0.0 4.9 3 1 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 VBB31207.1 - 2.5e-17 62.8 0.0 1.6e-08 34.6 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 VBB31207.1 - 7.8e-17 61.4 0.1 0.00077 19.6 0.0 5.6 3 2 0 3 3 3 3 Immunoglobulin V-set domain LRR_9 PF14580.6 VBB31207.1 - 2.8e-13 49.7 16.9 0.00099 18.7 1.9 4.3 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 VBB31207.1 - 6e-11 41.3 36.6 1.9 9.4 0.0 14.8 18 0 0 18 18 16 3 Leucine Rich Repeat LRR_6 PF13516.6 VBB31207.1 - 8.2e-08 31.7 43.5 0.41 10.8 0.0 13.8 16 0 0 16 16 14 1 Leucine Rich repeat LRRNT PF01462.18 VBB31207.1 - 6.7e-07 28.8 6.0 1.2e-06 28.0 4.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Ig_6 PF18452.1 VBB31207.1 - 1.6e-06 27.6 0.0 0.1 12.2 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 VBB31207.1 - 3.1e-05 24.0 0.0 0.44 10.6 0.0 3.1 3 0 0 3 3 2 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 VBB31207.1 - 0.0004 20.4 0.7 6.8 6.8 0.0 4.3 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 VBB31207.1 - 0.0016 18.7 0.0 0.72 10.1 0.0 2.7 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 C2-set PF05790.15 VBB31207.1 - 0.11 12.6 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin C2-set domain SCVP PF17619.2 VBB31208.1 - 1.9e-05 25.4 0.6 2.6e-05 25.0 0.6 1.2 1 0 0 1 1 1 1 Secreted clade V proteins DUF4041 PF13250.6 VBB31208.1 - 0.015 15.2 0.9 0.025 14.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Pox_Ag35 PF03286.14 VBB31208.1 - 0.044 13.6 2.1 0.058 13.2 2.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein 7TM_GPCR_Srbc PF10316.9 VBB31209.1 - 7e-15 55.3 1.4 7e-15 55.3 1.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srsx PF10320.9 VBB31209.1 - 5.7e-08 32.5 1.5 8.8e-08 31.8 1.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 VBB31209.1 - 1.1e-07 31.5 3.6 1.4e-07 31.2 3.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 VBB31209.1 - 5.2e-05 22.7 6.6 0.0002 20.7 6.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 VBB31209.1 - 0.00033 20.1 4.1 0.00041 19.8 4.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 VBB31209.1 - 0.00043 20.0 12.6 0.0019 17.9 7.1 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ATP-synt_8 PF00895.20 VBB31209.1 - 0.01 16.3 0.9 2.8 8.5 0.1 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 SHP PF03579.13 VBB31209.1 - 0.022 14.7 0.1 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 Small hydrophobic protein DUF3522 PF12036.8 VBB31209.1 - 0.025 14.9 1.5 0.041 14.2 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Afaf PF15339.6 VBB31209.1 - 0.1 12.3 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor Cadherin_C_2 PF16492.5 VBB31209.1 - 0.16 12.8 0.7 7.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal 7TM_GPCR_Srh PF10318.9 VBB31209.1 - 1.2 8.1 12.2 9.8 5.1 12.2 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Herpes_UL49_5 PF05702.11 VBB31209.1 - 3.9 7.6 9.4 5.7 7.1 0.3 3.7 2 1 1 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein 7TM_GPCR_Sru PF10322.9 VBB31209.1 - 4.9 6.4 11.7 0.088 12.1 4.4 1.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru TPR_2 PF07719.17 VBB31210.1 - 3.8e-10 39.1 1.4 0.043 13.9 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 VBB31210.1 - 1.6e-09 38.2 0.3 0.011 16.2 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB31210.1 - 1.8e-09 38.1 0.0 0.0033 18.0 0.1 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 VBB31210.1 - 4.9e-09 35.7 1.8 0.35 11.2 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB31210.1 - 3e-08 33.8 2.7 0.0017 19.0 0.1 5.6 2 1 6 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB31210.1 - 2.3e-06 27.2 0.8 15 5.9 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 VBB31210.1 - 2.7e-06 27.9 0.1 0.027 14.9 0.1 2.4 1 1 1 2 2 2 2 Alkyl sulfatase dimerisation TPR_6 PF13174.6 VBB31210.1 - 2.2e-05 24.8 0.7 14 6.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.8 VBB31210.1 - 7.7e-05 21.8 0.6 0.002 17.1 0.1 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 VBB31210.1 - 0.0062 16.3 1.3 7.8 6.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB31210.1 - 0.0063 16.8 0.3 8.3 7.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 VBB31210.1 - 0.083 13.2 0.1 7.4 7.0 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 VBB31210.1 - 0.14 12.4 2.5 19 5.5 0.1 2.9 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB31210.1 - 0.33 11.2 2.1 26 5.1 0.1 3.2 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Aldedh PF00171.22 VBB31211.1 - 2.1e-99 333.2 0.0 2.8e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 VBB31212.1 - 1.4e-63 214.8 1.8 1.6e-63 214.6 1.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31212.1 - 7.1e-39 133.7 0.5 8.5e-39 133.4 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31212.1 - 7.2e-07 28.8 0.0 8.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 VBB31212.1 - 0.00051 19.7 0.1 0.00084 19.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 VBB31212.1 - 0.0019 17.2 0.1 0.0029 16.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB31212.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 VBB31212.1 - 0.019 14.5 0.2 0.038 13.5 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 VBB31212.1 - 0.02 14.2 0.6 0.057 12.8 0.2 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 VBB31212.1 - 0.062 12.9 0.2 0.096 12.3 0.2 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 VBB31213.1 - 5.1e-14 52.3 0.0 6.2e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31213.1 - 0.00011 21.5 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31213.1 - 0.00026 19.9 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB31213.1 - 0.0095 15.9 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 VBB31213.1 - 0.048 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4071 PF13281.6 VBB31214.1 - 3.9e-06 26.2 0.1 2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) DRMBL PF07522.14 VBB31215.1 - 0.00085 19.5 0.1 0.0022 18.2 0.1 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Utp13 PF08625.11 VBB31215.1 - 0.042 13.8 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Tetraspanin PF00335.20 VBB31216.1 - 0.009 15.7 0.7 0.012 15.3 0.2 1.6 1 1 0 1 1 1 1 Tetraspanin family Motile_Sperm PF00635.26 VBB31217.1 - 0.0015 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PRP38 PF03371.15 VBB31218.1 - 7.6e-61 205.0 1.7 9.7e-61 204.6 1.7 1.1 1 0 0 1 1 1 1 PRP38 family DUF4228 PF14009.6 VBB31218.1 - 0.012 16.1 3.9 0.018 15.4 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) PRP38_assoc PF12871.7 VBB31218.1 - 0.027 15.1 67.5 0.4 11.3 67.5 2.3 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Use1 PF09753.9 VBB31218.1 - 1.1 9.0 9.4 1.5 8.4 9.4 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 ELMO_CED12 PF04727.13 VBB31219.1 - 1.4e-15 57.9 0.0 2.9e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 VBB31219.1 - 1.9e-06 28.5 0.0 1.2e-05 25.8 0.0 2.2 1 1 1 2 2 2 1 Pleckstrin homology domain DUF4220 PF13968.6 VBB31219.1 - 0.0013 18.2 0.3 0.0018 17.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) Frizzled PF01534.17 VBB31220.1 - 5.9e-34 117.6 9.6 8.1e-34 117.1 9.6 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 VBB31220.1 - 1.9e-07 31.7 0.3 1.9e-07 31.7 0.3 2.5 2 1 0 2 2 2 1 Fz domain 7tm_2 PF00002.24 VBB31220.1 - 0.0029 16.9 10.1 0.0048 16.2 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PI-PLC-X PF00388.19 VBB31221.1 - 2.7e-59 198.9 0.0 6e-59 197.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 VBB31221.1 - 3.5e-43 146.6 0.1 3.5e-43 146.6 0.1 3.2 4 0 0 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 VBB31221.1 - 8.4e-26 90.4 0.0 2.6e-25 88.8 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF1154 PF06631.11 VBB31221.1 - 1.3e-14 54.0 15.4 1.3e-14 54.0 15.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 VBB31221.1 - 9.4e-11 42.1 0.1 9.4e-11 42.1 0.1 3.7 5 0 0 5 5 5 1 Phosphoinositide-specific phospholipase C, efhand-like CobN-Mg_chel PF02514.16 VBB31221.1 - 9.6 3.8 17.0 14 3.2 17.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase IF4E PF01652.18 VBB31222.1 - 1.2e-55 187.6 1.1 1.7e-55 187.2 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E USP8_dimer PF08969.11 VBB31223.1 - 3e-31 108.0 0.8 4.2e-31 107.5 0.8 1.2 1 0 0 1 1 1 1 USP8 dimerisation domain PhoH PF02562.16 VBB31223.1 - 0.037 13.5 0.1 3.6 7.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF2385 PF09539.10 VBB31223.1 - 0.051 14.1 0.2 0.12 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) PH PF00169.29 VBB31223.1 - 0.31 11.6 4.6 0.23 12.0 0.3 2.5 2 1 1 3 3 3 0 PH domain RRM_1 PF00076.22 VBB31225.1 - 7.4e-28 96.2 0.2 6.7e-10 38.6 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 VBB31225.1 - 9.3e-05 22.6 20.4 0.00015 21.9 20.4 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein RRM_occluded PF16842.5 VBB31225.1 - 0.0059 16.4 0.0 16 5.4 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif PRP38_assoc PF12871.7 VBB31225.1 - 0.028 15.0 41.5 0.063 13.9 41.5 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 VBB31225.1 - 0.082 11.7 6.5 0.12 11.2 6.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_9 PF18444.1 VBB31225.1 - 0.15 11.9 0.1 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Zip PF02535.22 VBB31225.1 - 0.2 10.8 0.1 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 VBB31225.1 - 1.1 7.5 19.3 1.6 6.9 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 VBB31225.1 - 1.8 7.3 8.8 2.4 6.8 8.8 1.1 1 0 0 1 1 1 0 Presenilin UQ_con PF00179.26 VBB31226.1 - 1.8e-06 27.6 0.0 2e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_transf_92 PF01697.27 VBB31227.1 - 2.9e-30 105.8 3.8 5.1e-30 105.0 3.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 WD40 PF00400.32 VBB31228.1 - 1.4e-27 95.3 18.9 2e-05 25.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31228.1 - 5.8e-06 26.5 0.7 6.4 7.2 0.0 4.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB31228.1 - 0.00015 21.2 1.2 0.12 11.7 0.0 3.0 2 1 1 3 3 3 3 WD40-like domain Cytochrom_D1 PF02239.16 VBB31228.1 - 0.00018 20.2 0.4 0.0018 16.9 0.2 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain S4 PF01479.25 VBB31230.1 - 2.8e-09 36.5 1.7 2.8e-09 36.5 1.7 2.3 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 VBB31230.1 - 2.7e-05 25.0 0.4 5e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ion_trans PF00520.31 VBB31232.1 - 1.4e-44 152.2 20.7 2e-26 92.7 7.3 3.3 2 1 1 3 3 3 3 Ion transport protein GPHH PF16905.5 VBB31232.1 - 6.7e-31 105.8 0.1 1.3e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 VBB31232.1 - 1.7e-28 98.6 0.2 3.5e-28 97.6 0.2 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain CC190 PF15768.5 VBB31232.1 - 0.0096 16.0 4.3 0.015 15.3 4.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 190 OB_NTP_bind PF07717.16 VBB31233.1 - 9.7e-11 41.9 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 VBB31233.1 - 2.2e-10 40.8 0.0 6.2e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Helicase associated domain (HA2) T-box PF00907.22 VBB31234.1 - 2e-59 200.9 0.1 2.4e-59 200.7 0.1 1.0 1 0 0 1 1 1 1 T-box Homeodomain PF00046.29 VBB31235.1 - 1.7e-21 75.8 4.9 3e-21 75.0 4.9 1.4 1 0 0 1 1 1 1 Homeodomain Sigma70_r4_2 PF08281.12 VBB31235.1 - 0.024 14.3 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 UCH PF00443.29 VBB31236.1 - 2.1e-36 125.7 0.0 3.3e-36 125.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB31236.1 - 9.8e-18 64.8 2.0 1.4e-17 64.3 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TGT PF01702.18 VBB31238.1 - 5.5e-44 150.7 0.0 8e-35 120.6 0.0 3.1 2 1 1 3 3 3 3 Queuine tRNA-ribosyltransferase DUF2315 PF10231.9 VBB31238.1 - 6.5e-30 103.7 2.0 1.3e-29 102.8 2.0 1.4 1 0 0 1 1 1 1 Apoptogenic protein 1 Peptidase_S37 PF05576.11 VBB31238.1 - 0.12 11.0 0.0 0.26 9.9 0.0 1.5 2 0 0 2 2 2 0 PS-10 peptidase S37 MEA1 PF06910.11 VBB31239.1 - 2.8e-10 40.9 0.0 3.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) CP2 PF04516.15 VBB31240.1 - 9.6e-34 116.7 0.1 1.5e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 VBB31240.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PPR_3 PF13812.6 VBB31240.1 - 0.023 14.8 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain ATPase PF06745.13 VBB31241.1 - 0.018 14.4 0.2 3.8 6.8 0.2 2.3 1 1 1 2 2 2 0 KaiC PH PF00169.29 VBB31241.1 - 0.087 13.3 0.0 0.3 11.6 0.0 2.0 1 0 0 1 1 1 0 PH domain Glyco_hydro_18 PF00704.28 VBB31242.1 - 1.5e-49 169.4 1.4 1.7e-49 169.2 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PB1-F2 PF11986.8 VBB31242.1 - 0.035 14.3 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Influenza A Proapoptotic protein YBD PF17725.1 VBB31243.1 - 1.5e-86 289.6 0.1 1.9e-86 289.2 0.1 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 VBB31243.1 - 3.1e-26 91.2 0.0 6e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain HNF_C PF09354.10 VBB31243.1 - 0.15 13.1 0.9 0.34 12.0 0.0 2.0 2 0 0 2 2 2 0 HNF3 C-terminal domain BK_channel_a PF03493.18 VBB31245.1 - 4.6e-26 90.9 0.2 1.1e-25 89.7 0.2 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 VBB31245.1 - 9.2e-14 51.2 4.3 9.2e-14 51.2 4.3 2.0 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 VBB31245.1 - 0.0013 19.0 0.1 0.57 10.5 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ntox33 PF15533.6 VBB31245.1 - 0.22 12.0 0.3 12 6.4 0.1 2.4 2 0 0 2 2 2 0 Bacterial toxin 33 Lig_chan PF00060.26 VBB31245.1 - 0.54 10.1 2.5 2.8 7.8 2.1 2.3 2 1 0 2 2 2 0 Ligand-gated ion channel Ion_trans PF00520.31 VBB31245.1 - 1.6 7.9 19.1 0.68 9.1 16.0 1.8 2 0 0 2 2 2 0 Ion transport protein ELO PF01151.18 VBB31246.1 - 3e-32 112.1 10.1 3.7e-32 111.8 10.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Phage_holin_Dp1 PF16938.5 VBB31246.1 - 0.18 12.0 3.3 1.1 9.5 0.1 3.0 3 0 0 3 3 3 0 Putative phage holin Dp-1 DUF5337 PF17272.2 VBB31246.1 - 0.41 10.5 9.8 0.61 10.0 2.3 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5337) WD40 PF00400.32 VBB31247.1 - 2e-27 94.9 4.4 2.2e-07 31.5 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Utp12 PF04003.12 VBB31247.1 - 4.1e-14 52.8 0.0 7.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 VBB31247.1 - 3.5e-13 49.6 0.1 6.3e-06 26.4 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB31247.1 - 0.00099 19.0 0.0 0.025 14.5 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A SH3_9 PF14604.6 VBB31248.1 - 2e-07 30.8 0.0 3.7e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 VBB31248.1 - 4e-06 26.3 0.0 7.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB31248.1 - 4.5e-06 26.2 0.0 8.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HA2 PF04408.23 VBB31249.1 - 8e-13 48.6 0.1 2e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) IBR PF01485.21 VBB31249.1 - 2.7e-12 46.7 32.4 4.2e-09 36.5 8.4 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Helicase_C PF00271.31 VBB31249.1 - 3.1e-12 46.8 0.0 8.9e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 VBB31249.1 - 9.1e-09 35.6 0.0 2.3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 VBB31249.1 - 1.1e-07 31.8 0.0 3.1e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase RRM_1 PF00076.22 VBB31249.1 - 0.00065 19.5 0.3 0.002 17.9 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLS PF14611.6 VBB31249.1 - 0.0035 17.2 0.0 1.3 8.8 0.0 2.8 1 1 1 2 2 2 2 Mitochondrial inner-membrane-bound regulator ResIII PF04851.15 VBB31249.1 - 0.005 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 VBB31249.1 - 0.0062 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_2 PF14445.6 VBB31249.1 - 0.18 12.0 13.4 0.066 13.4 3.1 3.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 C2 PF00168.30 VBB31250.1 - 1.8e-34 118.1 0.0 8.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain Amnionless PF14828.6 VBB31251.1 - 3.5e-17 62.4 0.1 6e-17 61.6 0.1 1.4 1 1 0 1 1 1 1 Amnionless Hexokinase_2 PF03727.16 VBB31252.1 - 3.4e-80 268.9 0.3 6.1e-53 179.7 0.1 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 VBB31252.1 - 0.00035 20.5 0.4 0.00069 19.6 0.4 1.5 1 0 0 1 1 1 1 Hexokinase ETF PF01012.21 VBB31253.1 - 1.4e-37 129.3 0.4 2.2e-37 128.7 0.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 VBB31253.1 - 2.4e-37 126.8 1.4 5.2e-37 125.7 1.4 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain RRM_1 PF00076.22 VBB31254.1 - 9.5e-11 41.4 0.1 1.8e-07 30.9 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CoaE PF01121.20 VBB31255.1 - 1.1e-42 145.8 0.1 2.6e-42 144.5 0.1 1.6 2 0 0 2 2 2 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 VBB31255.1 - 3.4e-08 33.8 0.1 3e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 VBB31255.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD synthetase AAA_18 PF13238.6 VBB31255.1 - 0.017 15.7 0.1 0.19 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain SH2 PF00017.24 VBB31256.1 - 3.3e-11 43.1 0.0 7.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain ABC_membrane_2 PF06472.15 VBB31257.1 - 3.2e-62 210.4 6.6 4.1e-62 210.0 6.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 VBB31257.1 - 4.8e-15 56.3 0.0 9.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ICE2 PF08426.10 VBB31257.1 - 0.0021 17.2 1.7 0.0021 17.2 1.7 1.8 2 0 0 2 2 2 1 ICE2 AAA_16 PF13191.6 VBB31257.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain bZIP_1 PF00170.21 VBB31258.1 - 6.4e-06 26.2 12.4 6.4e-06 26.2 12.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 VBB31258.1 - 0.0013 18.8 13.0 0.0013 18.8 13.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper NapE PF06796.11 VBB31260.1 - 0.035 13.6 1.5 0.072 12.6 1.5 1.6 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE TraT PF05818.12 VBB31260.1 - 2.1 8.0 5.0 2.3 7.9 5.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein AAA PF00004.29 VBB31261.1 - 2.1e-41 141.4 0.0 6e-41 140.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB31261.1 - 9.4e-11 41.4 1.0 1.6e-10 40.6 1.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 VBB31261.1 - 2.9e-10 39.9 0.0 6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 VBB31261.1 - 4.2e-06 27.1 0.4 0.0034 17.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 VBB31261.1 - 9.7e-06 25.8 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 VBB31261.1 - 4.8e-05 22.6 0.0 8.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 VBB31261.1 - 0.00031 21.3 0.1 0.0013 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 VBB31261.1 - 0.0005 19.7 0.7 0.0042 16.7 0.0 2.6 3 0 0 3 3 3 1 Proteasomal ATPase OB N-terminal domain RuvB_N PF05496.12 VBB31261.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 VBB31261.1 - 0.0013 18.8 0.2 0.0075 16.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 VBB31261.1 - 0.0013 19.0 0.3 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB31261.1 - 0.0039 17.6 0.8 0.052 13.9 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 VBB31261.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB31261.1 - 0.014 15.8 0.0 0.17 12.3 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_3 PF07726.11 VBB31261.1 - 0.019 14.8 0.1 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 VBB31261.1 - 0.028 14.2 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 VBB31261.1 - 0.029 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 VBB31261.1 - 0.039 13.3 0.1 0.62 9.4 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 VBB31261.1 - 0.042 13.4 0.5 3.9 7.0 0.1 2.5 1 1 1 2 2 2 0 AAA domain DUF3363 PF11843.8 VBB31261.1 - 0.071 12.0 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) Mg_chelatase PF01078.21 VBB31261.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 VBB31261.1 - 0.13 11.4 0.0 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 VBB31261.1 - 0.14 11.8 0.1 0.37 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 VBB31261.1 - 0.17 11.8 0.2 2.4 8.1 0.1 2.6 2 1 1 3 3 3 0 NACHT domain SDA1 PF05285.12 VBB31262.1 - 8.7e-60 203.0 26.6 2.1e-30 106.3 19.2 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 VBB31262.1 - 2.6e-14 53.2 0.0 5.1e-13 49.1 0.0 2.7 2 0 0 2 2 2 1 NUC130/3NT domain YL1 PF05764.13 VBB31262.1 - 0.02 15.0 1.2 0.02 15.0 1.2 2.6 2 1 0 2 2 2 0 YL1 nuclear protein HEAT_2 PF13646.6 VBB31262.1 - 0.03 14.7 0.0 5.9 7.4 0.0 2.9 1 1 1 2 2 2 0 HEAT repeats Cnd1 PF12717.7 VBB31262.1 - 0.082 12.9 2.8 0.13 12.3 0.4 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vitellogenin_N PF01347.22 VBB31264.1 - 9.2e-58 196.1 0.1 1.6e-57 195.3 0.1 1.4 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 VBB31264.1 - 1.9e-46 158.8 0.2 4.1e-46 157.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) MOZART1 PF12554.8 VBB31264.1 - 5.9 6.8 5.3 1.8 8.4 0.2 2.8 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated UQ_con PF00179.26 VBB31266.1 - 4.2e-34 117.2 0.0 6.3e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bap31 PF05529.12 VBB31267.1 - 3.3e-40 137.1 4.9 4.8e-40 136.5 4.9 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 VBB31267.1 - 5.1e-14 52.0 5.7 5.1e-14 52.0 5.7 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0242 PF06785.11 VBB31267.1 - 0.016 15.3 1.8 0.035 14.2 1.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PhoLip_ATPase_N PF16209.5 VBB31267.1 - 0.038 13.7 0.3 0.084 12.6 0.3 1.7 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal TRAPP PF04051.16 VBB31267.1 - 0.16 11.7 0.2 0.94 9.2 0.0 2.0 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component MCU PF04678.13 VBB31267.1 - 0.88 9.6 4.1 1.3 9.1 4.1 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Armet PF10208.9 VBB31268.1 - 5.5e-56 188.5 5.5 5.5e-56 188.5 5.5 2.2 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding UQ_con PF00179.26 VBB31268.1 - 2.2e-46 157.0 0.0 5.8e-46 155.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Clc-like PF07062.12 VBB31268.1 - 5.3e-26 91.4 6.0 9.8e-26 90.5 6.0 1.4 1 0 0 1 1 1 1 Clc-like Claudin_2 PF13903.6 VBB31268.1 - 0.00052 19.8 3.0 0.0012 18.6 3.0 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 VBB31268.1 - 0.0086 16.0 5.2 0.031 14.2 0.4 2.4 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family Prok-E2_B PF14461.6 VBB31268.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 VBB31268.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 VBB31269.1 - 3.8e-50 170.7 2.1 7.4e-50 169.8 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31269.1 - 5.2e-40 137.4 0.0 3.1e-39 134.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 VBB31269.1 - 1.1e-15 57.6 4.4 1.1e-15 57.6 4.4 3.0 3 0 0 3 3 3 2 Oxidative-stress-responsive kinase 1 C-terminal domain Ndc1_Nup PF09531.10 VBB31271.1 - 2.5 6.7 7.7 0.28 9.8 0.3 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Collagen PF01391.18 VBB31272.1 - 1.3e-22 79.3 64.5 1.6e-08 34.1 24.1 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB31272.1 - 0.017 15.1 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain CaKB PF03185.15 VBB31272.1 - 0.038 13.7 0.1 0.046 13.4 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DUF3333 PF11812.8 VBB31272.1 - 0.14 12.4 0.1 0.21 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) BET PF17035.5 VBB31273.1 - 8.1e-23 80.4 0.2 2.3e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 VBB31273.1 - 2.2e-20 72.5 1.5 1.3e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 Bromodomain BRD4_CDT PF17105.5 VBB31273.1 - 3.4e-10 39.3 6.6 3.4e-10 39.3 6.6 2.9 2 1 0 2 2 2 1 C-terminal domain of bromodomain protein 4 ATS PF15445.6 VBB31273.1 - 0.047 13.1 0.7 0.085 12.2 0.7 1.3 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Na_H_Exchanger PF00999.21 VBB31274.1 - 5.1e-71 239.5 36.2 1.3e-69 234.8 36.2 2.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2181 PF10223.9 VBB31275.1 - 7.7e-46 156.5 0.1 1e-45 156.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) zf-CXXC PF02008.20 VBB31276.1 - 4.1 7.5 17.6 8.3 6.5 8.2 2.2 2 0 0 2 2 2 0 CXXC zinc finger domain Allatostatin PF05953.12 VBB31276.1 - 4.3 8.3 9.3 1.7e+02 3.4 0.1 4.8 5 0 0 5 5 5 0 Allatostatin Pullulanase_Ins PF18494.1 VBB31277.1 - 0.013 15.9 0.9 0.046 14.2 0.1 2.0 2 0 0 2 2 2 0 Pullulanase Ins domain ANAPC5 PF12862.7 VBB31277.1 - 0.02 14.9 1.7 0.03 14.4 0.5 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 ABC_tran_Xtn PF12848.7 VBB31277.1 - 0.061 13.4 0.6 0.061 13.4 0.6 2.0 2 1 0 2 2 2 0 ABC transporter WXG100 PF06013.12 VBB31277.1 - 0.064 13.5 2.7 0.93 9.8 0.3 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG HxlR PF01638.17 VBB31277.1 - 0.081 12.8 0.5 0.21 11.5 0.5 1.8 1 1 0 1 1 1 0 HxlR-like helix-turn-helix IATP PF04568.12 VBB31277.1 - 0.086 13.3 1.1 0.086 13.3 1.1 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SF1-HH PF16275.5 VBB31277.1 - 0.088 13.1 4.5 2.9 8.3 0.3 2.2 1 1 1 2 2 2 0 Splicing factor 1 helix-hairpin domain Fib_alpha PF08702.10 VBB31277.1 - 0.095 12.9 9.0 0.065 13.4 7.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 VBB31277.1 - 0.098 12.0 3.5 0.12 11.8 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 VBB31277.1 - 0.12 12.7 5.0 0.22 11.8 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 VBB31277.1 - 0.67 8.5 7.0 0.83 8.2 7.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Spc34 PF08657.10 VBB31277.1 - 0.69 9.7 9.2 1.4 8.7 9.2 1.7 1 1 0 1 1 1 0 DASH complex subunit Spc34 Cep57_MT_bd PF06657.13 VBB31277.1 - 0.71 10.4 10.7 0.25 11.8 1.1 3.2 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FliD_N PF02465.18 VBB31277.1 - 0.93 10.2 7.1 2.5 8.9 0.6 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CorA PF01544.18 VBB31277.1 - 1.2 8.4 7.4 2 7.7 7.4 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4140 PF13600.6 VBB31277.1 - 1.8 9.0 5.0 28 5.2 5.0 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 VBB31277.1 - 2.2 8.3 9.2 6.8 6.7 1.6 2.2 1 1 1 2 2 2 0 Laminin Domain II XhlA PF10779.9 VBB31277.1 - 2.2 8.5 7.7 0.18 12.0 1.5 2.2 2 1 0 2 2 2 0 Haemolysin XhlA Med4 PF10018.9 VBB31277.1 - 3.1 7.4 9.9 0.26 10.9 2.0 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF16 PF01519.16 VBB31277.1 - 3.4 8.2 9.0 77 3.8 9.0 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 BST2 PF16716.5 VBB31277.1 - 8.1 7.1 12.5 13 6.5 2.2 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Pkinase PF00069.25 VBB31278.1 - 4.4e-12 45.9 0.0 6.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31278.1 - 0.0018 17.6 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31278.1 - 0.038 12.8 0.1 0.081 11.7 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase YcxB PF14317.6 VBB31278.1 - 0.067 12.9 0.4 0.51 10.1 0.2 2.4 2 0 0 2 2 2 0 YcxB-like protein SWIRM-assoc_1 PF16495.5 VBB31279.1 - 1.9e-30 104.6 14.8 4.1e-30 103.6 14.8 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 VBB31279.1 - 2.4e-29 101.5 0.6 4.5e-29 100.6 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_3 PF16498.5 VBB31279.1 - 1.8e-23 82.5 4.5 1.8e-23 82.5 4.5 3.0 3 0 0 3 3 3 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 VBB31279.1 - 4.4e-10 39.6 0.0 7.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 VBB31279.1 - 2.4e-07 30.9 0.0 4.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_ner PF04546.13 VBB31279.1 - 2.4 8.0 16.7 0.58 10.0 12.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region SLD5_C PF16922.5 VBB31280.1 - 5.8e-07 29.6 0.0 1.2e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 VBB31280.1 - 0.00072 20.0 2.3 0.0018 18.7 2.2 1.8 1 1 0 1 1 1 1 GINS complex protein DNA_pol3_a_NII PF11490.8 VBB31280.1 - 0.043 13.7 0.6 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF1057 PF06342.12 VBB31281.1 - 2.8e-59 200.6 0.1 3.4e-59 200.3 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 VBB31281.1 - 6.4e-16 58.8 0.2 1.5e-13 51.0 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB31281.1 - 8.3e-12 44.9 0.0 8e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 VBB31281.1 - 0.0002 22.0 0.0 0.00025 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 VBB31281.1 - 0.088 12.7 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 VBB31281.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Proteasome PF00227.26 VBB31282.1 - 2.4e-43 147.8 0.7 3e-43 147.5 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 VBB31282.1 - 0.00081 18.7 0.0 0.00081 18.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Pkinase PF00069.25 VBB31283.1 - 1e-34 120.1 0.1 1.4e-34 119.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31283.1 - 1.5e-11 44.1 0.1 6.8e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 VBB31283.1 - 0.031 13.6 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 VBB31284.1 - 9.2e-12 44.5 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 VBB31284.1 - 0.0086 16.0 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding Archease PF01951.16 VBB31284.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) UIM PF02809.20 VBB31285.1 - 0.11 12.5 2.1 0.34 10.9 2.1 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Plus-3 PF03126.18 VBB31286.1 - 1.8e-32 112.1 1.5 6.5e-32 110.3 0.2 2.6 2 0 0 2 2 2 1 Plus-3 domain Viral_P18 PF04521.13 VBB31286.1 - 0.19 11.5 8.4 3.6 7.4 0.3 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CSD PF00313.22 VBB31287.1 - 4.3e-28 97.0 0.3 7.8e-28 96.1 0.3 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain TIMELESS PF04821.14 VBB31288.1 - 2.6e-47 161.4 0.3 2.6e-47 161.4 0.3 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 VBB31288.1 - 5.9e-27 95.0 1.6 2e-25 90.0 0.1 2.9 2 1 0 2 2 2 1 Timeless protein C terminal region SapB_1 PF05184.15 VBB31288.1 - 0.0089 16.0 0.3 9.5 6.4 0.2 3.6 4 0 0 4 4 4 2 Saposin-like type B, region 1 MRP-S24 PF14955.6 VBB31288.1 - 0.015 15.3 0.1 0.48 10.4 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 DUF4196 PF13846.6 VBB31288.1 - 1.5 9.0 8.7 0.13 12.5 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) CDT1_C PF16679.5 VBB31288.1 - 7.8 7.0 7.7 6.9 7.2 0.1 3.4 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Cohesin_load PF10345.9 VBB31289.1 - 1.8e-21 76.3 20.5 2.9e-21 75.6 20.5 1.2 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 VBB31289.1 - 0.00067 19.9 1.5 6 7.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 VBB31289.1 - 0.0059 16.3 0.6 0.11 12.1 0.2 2.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 VBB31289.1 - 1 8.9 8.2 1.3 8.6 0.7 3.7 3 1 1 4 4 4 0 ComR tetratricopeptide TPR_8 PF13181.6 VBB31289.1 - 1.3 9.4 6.8 26 5.4 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PAX PF00292.18 VBB31290.1 - 1.3e-67 225.5 0.6 1.6e-67 225.1 0.6 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 VBB31290.1 - 4.1e-05 23.2 0.0 9.1e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 VBB31290.1 - 0.00067 20.2 0.0 0.12 13.0 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 VBB31290.1 - 0.001 18.6 0.0 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 InsA C-terminal domain HTH_38 PF13936.6 VBB31290.1 - 0.039 13.7 0.1 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 VBB31290.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase_Tyr PF07714.17 VBB31291.1 - 7.3e-71 238.5 0.0 1.8e-70 237.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB31291.1 - 1.7e-43 148.9 0.0 3.8e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain MA3 PF02847.17 VBB31291.1 - 8.6e-22 77.3 2.0 2e-21 76.0 2.0 1.6 1 0 0 1 1 1 1 MA3 domain SH2 PF00017.24 VBB31291.1 - 1.5e-11 44.2 0.2 4.8e-11 42.6 0.2 2.0 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 VBB31291.1 - 0.015 14.7 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AF-4 PF05110.13 VBB31291.1 - 8.4 4.3 42.7 14 3.6 42.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 7TM_GPCR_Srx PF10328.9 VBB31292.1 - 1e-07 31.9 8.5 1.1e-07 31.7 8.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DAGK_cat PF00781.24 VBB31293.1 - 2.4e-23 82.1 0.0 4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Glyco_transf_7N PF13733.6 VBB31293.1 - 0.46 10.1 5.6 0.45 10.2 0.1 2.3 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 CTP_synth_N PF06418.14 VBB31294.1 - 3.3e-118 393.8 0.1 4.6e-118 393.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 VBB31294.1 - 8.3e-46 156.2 0.5 5.6e-37 127.4 0.1 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I MRP-S34 PF16053.5 VBB31294.1 - 2.2e-37 127.6 0.1 3.9e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Peptidase_C26 PF07722.13 VBB31294.1 - 0.00016 21.5 2.0 0.24 11.1 0.2 2.6 2 0 0 2 2 2 2 Peptidase C26 CbiA PF01656.23 VBB31294.1 - 0.00025 21.1 0.0 0.00046 20.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 VBB31294.1 - 0.04 12.9 0.3 0.078 11.9 0.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 VBB31294.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase SgrT PF15894.5 VBB31295.1 - 0.029 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Neur_chan_LBD PF02931.23 VBB31298.1 - 2.5e-33 115.3 1.7 2.8e-33 115.2 1.7 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Actin PF00022.19 VBB31300.1 - 1.8e-126 422.1 0.0 2e-126 421.9 0.0 1.0 1 0 0 1 1 1 1 Actin UBA_4 PF14555.6 VBB31301.1 - 4.4e-08 32.8 0.1 9.3e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 VBB31301.1 - 1.1e-07 31.9 0.0 3.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 UBX domain NHase_alpha PF02979.16 VBB31301.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain CAML PF14963.6 VBB31301.1 - 1 9.4 5.8 0.31 11.1 2.0 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Spore_coat_CotO PF14153.6 VBB31301.1 - 1.4 8.8 10.6 0.09 12.7 4.4 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Hormone_recep PF00104.30 VBB31302.1 - 1.6e-13 50.7 4.3 1.6e-13 50.7 4.3 2.6 3 0 0 3 3 3 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 VBB31302.1 - 0.0053 17.2 3.4 0.0053 17.2 3.4 2.7 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Levi_coat PF01819.17 VBB31302.1 - 0.23 11.5 3.6 0.33 11.0 0.8 2.2 1 1 1 2 2 2 0 Levivirus coat protein PHD PF00628.29 VBB31303.1 - 9e-09 35.1 9.6 9e-09 35.1 9.6 2.3 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 VBB31303.1 - 0.0001 22.7 0.1 0.0001 22.7 0.1 3.9 4 0 0 4 4 4 1 SET domain PHD_2 PF13831.6 VBB31303.1 - 0.32 10.6 3.4 0.7 9.5 3.4 1.6 1 0 0 1 1 1 0 PHD-finger DEAD PF00270.29 VBB31304.1 - 7.8e-17 61.6 0.3 8.7e-16 58.2 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB31304.1 - 8.6e-15 55.2 0.5 2.1e-14 53.9 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 VBB31304.1 - 3.6e-14 53.0 0.1 1.3e-12 48.1 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain APT PF03440.14 VBB31304.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain DUF2053 PF09767.9 VBB31305.1 - 5.6e-28 98.1 4.3 8.1e-28 97.6 4.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) ArfGap PF01412.18 VBB31306.1 - 1.2e-40 138.2 0.0 3.8e-40 136.6 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 VBB31306.1 - 2e-11 44.3 5.8 3.5e-06 27.5 0.1 2.8 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 VBB31306.1 - 1.7e-08 35.0 0.4 3.7e-08 33.8 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB31306.1 - 1.2e-05 25.4 0.7 6.7e-05 23.1 0.3 2.4 3 0 0 3 3 2 1 Ankyrin repeats (many copies) PH_11 PF15413.6 VBB31306.1 - 4.7e-05 23.8 3.0 0.13 12.7 0.1 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain Ank PF00023.30 VBB31306.1 - 0.00033 21.0 0.8 0.0018 18.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 VBB31306.1 - 0.0041 17.7 0.1 0.31 11.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH_6 PF15406.6 VBB31306.1 - 0.0044 17.3 0.5 0.012 15.9 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.6 VBB31306.1 - 0.059 13.9 0.3 0.43 11.3 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat PH_9 PF15410.6 VBB31306.1 - 0.092 13.1 3.1 0.44 10.9 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain PH_8 PF15409.6 VBB31306.1 - 0.43 10.9 2.2 31 4.9 0.1 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain RRP7 PF12923.7 VBB31307.1 - 6e-29 100.6 10.5 6e-29 100.6 10.5 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain zf-NPL4 PF05020.15 VBB31307.1 - 0.0024 18.0 0.4 0.0059 16.8 0.4 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region RsmJ PF04378.13 VBB31307.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ PrmA PF06325.13 VBB31307.1 - 0.039 13.3 1.5 0.048 13.1 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Lyase_1 PF00206.20 VBB31308.1 - 2.6e-26 92.8 0.1 3.8e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 VBB31308.1 - 7.7e-06 26.4 0.1 2.5e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Dehydratase_SU PF02287.15 VBB31309.1 - 0.011 15.9 1.3 0.026 14.6 0.2 2.2 2 1 0 2 2 2 0 Dehydratase small subunit AGT PF11440.8 VBB31309.1 - 0.067 12.2 0.5 0.13 11.3 0.4 1.7 1 1 0 1 1 1 0 DNA alpha-glucosyltransferase C5-epim_C PF06662.13 VBB31311.1 - 9.9e-66 220.8 0.1 1.8e-65 219.9 0.1 1.5 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Prenyltrans PF00432.21 VBB31311.1 - 0.27 11.0 0.8 0.5 10.2 0.2 1.8 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat FGGY_N PF00370.21 VBB31312.1 - 2.8e-69 233.4 0.2 3.5e-69 233.1 0.2 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 VBB31312.1 - 0.0033 17.2 0.4 0.021 14.5 0.2 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Myb_DNA-binding PF00249.31 VBB31313.1 - 5.2e-13 49.0 0.1 3.9e-07 30.2 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 VBB31313.1 - 2.8e-08 33.9 2.6 0.0001 22.5 0.3 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF2839 PF10999.8 VBB31313.1 - 0.29 11.5 0.7 3.2 8.2 0.7 2.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Copine PF07002.16 VBB31314.1 - 9.1e-31 107.0 0.1 2e-30 105.9 0.1 1.5 2 0 0 2 2 2 1 Copine DUF551 PF04448.12 VBB31314.1 - 0.0042 18.0 0.0 0.011 16.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF551) C2 PF00168.30 VBB31314.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 C2 domain DUF3228 PF11539.8 VBB31314.1 - 0.083 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Thiolase_N PF00108.23 VBB31315.1 - 1.2e-79 267.3 0.1 2.4e-79 266.4 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 VBB31315.1 - 3.8e-39 133.1 0.9 1e-38 131.8 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 VBB31315.1 - 4.5e-12 46.1 0.7 4.7e-07 29.7 0.7 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 VBB31315.1 - 0.001 18.9 3.6 0.023 14.6 0.3 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRIF1 PF15741.5 VBB31315.1 - 0.13 10.8 0.1 0.2 10.1 0.1 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Arrestin_N PF00339.29 VBB31316.1 - 1e-18 67.8 0.2 1.3e-13 51.2 0.1 2.6 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 VBB31316.1 - 2.8e-17 63.4 0.2 2.4e-12 47.4 0.0 3.1 2 1 0 3 3 3 3 Arrestin (or S-antigen), C-terminal domain Auts2 PF15336.6 VBB31317.1 - 0.00039 20.6 2.8 0.00039 20.6 2.8 4.5 2 2 3 5 5 5 1 Autism susceptibility gene 2 protein PRIMA1 PF16101.5 VBB31317.1 - 0.16 12.0 13.6 1.4 9.0 2.6 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Aminotran_1_2 PF00155.21 VBB31318.1 - 3.1e-12 46.3 0.0 3.6e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RraB PF06877.11 VBB31318.1 - 0.015 16.0 0.0 0.027 15.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of ribonuclease activity B HTH_57 PF18679.1 VBB31318.1 - 0.029 14.7 0.0 1.7 9.0 0.0 2.3 1 1 1 2 2 2 0 ThcOx helix turn helix domain Trehalase PF01204.18 VBB31319.1 - 1.8e-112 376.8 10.8 2.8e-75 254.1 4.9 2.1 1 1 1 2 2 2 2 Trehalase Glyco_hydro_63 PF03200.16 VBB31319.1 - 0.00025 20.0 6.7 0.066 11.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain HYLS1_C PF15311.6 VBB31319.1 - 0.01 16.6 2.7 0.72 10.6 0.2 2.8 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Aminotran_1_2 PF00155.21 VBB31320.1 - 1.1e-28 100.5 0.0 1.6e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4477 PF14780.6 VBB31320.1 - 4.1e-15 55.9 8.0 6.7e-15 55.2 8.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) CH PF00307.31 VBB31321.1 - 2.2e-24 85.7 0.0 2.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB31321.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.11 VBB31321.1 - 0.032 14.5 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin SAM_adeno_trans PF01887.16 VBB31321.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase CAP_GLY PF01302.25 VBB31323.1 - 4.2e-25 87.6 1.5 6.3e-25 87.0 1.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 VBB31323.1 - 1.7e-15 57.2 0.2 8.1e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-like domain SERTA PF06031.13 VBB31324.1 - 4.5e-05 23.0 0.9 8.4e-05 22.2 0.9 1.5 1 0 0 1 1 1 1 SERTA motif DIPSY PF11763.8 VBB31324.1 - 0.013 15.7 0.5 1.9 8.7 0.1 2.6 1 1 1 2 2 2 0 Cell-wall adhesin ligand-binding C-terminal Sacchrp_dh_NADP PF03435.18 VBB31325.1 - 3.4e-19 69.4 0.2 5.6e-19 68.7 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 VBB31325.1 - 0.0044 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 VBB31325.1 - 0.0092 15.9 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 VBB31325.1 - 0.044 13.3 0.4 0.072 12.6 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.24 VBB31325.1 - 0.11 12.9 0.1 0.24 11.9 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HCO3_cotransp PF00955.21 VBB31325.1 - 0.12 11.2 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 HCO3- transporter family Rhodanese PF00581.20 VBB31326.1 - 3.2e-16 59.8 0.0 1.4e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RICTOR_V PF14668.6 VBB31327.1 - 1.5e-15 57.2 0.0 6.8e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 VBB31327.1 - 7.5e-14 52.0 0.0 2.2e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 VBB31327.1 - 2.4e-07 30.5 0.2 9.8e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain DB PF01682.19 VBB31328.1 - 4.5e-12 46.1 7.6 4.5e-12 46.1 7.6 1.8 2 0 0 2 2 2 1 DB module DUF5528 PF17666.1 VBB31328.1 - 0.34 10.8 2.3 0.61 10.0 0.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5528) RICTOR_N PF14664.6 VBB31329.1 - 1.1e-08 34.5 0.4 1.5e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 VBB31329.1 - 0.0016 18.2 0.0 0.0087 15.8 0.0 2.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain Guanylate_kin PF00625.21 VBB31331.1 - 1.7e-48 164.7 0.0 3.2e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 VBB31331.1 - 3.9e-09 36.1 0.0 1.2e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB31331.1 - 8.8e-07 28.4 0.6 4.8e-06 26.1 0.6 2.3 1 1 0 1 1 1 1 SH3 domain PDZ PF00595.24 VBB31331.1 - 1.8e-06 28.2 0.5 4.2e-06 27.0 0.5 1.6 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 VBB31331.1 - 2.5e-05 24.0 0.0 7.6e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 VBB31331.1 - 0.0023 17.7 0.1 0.0072 16.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Exonuc_VII_L PF02601.15 VBB31331.1 - 0.087 12.4 0.5 0.17 11.4 0.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PDZ_6 PF17820.1 VBB31332.1 - 4.4e-10 39.3 0.1 1.1e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 VBB31332.1 - 0.0003 21.1 0.0 0.00047 20.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB31332.1 - 0.00072 19.8 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 VBB31332.1 - 0.055 13.5 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain Septin PF00735.18 VBB31333.1 - 1.8e-105 352.3 0.3 3.1e-105 351.5 0.3 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 VBB31333.1 - 5.9e-07 29.6 0.2 1.7e-06 28.1 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB31333.1 - 0.0001 22.2 0.0 0.0077 16.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 VBB31333.1 - 0.00021 20.7 0.5 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AIG1 PF04548.16 VBB31333.1 - 0.00026 20.4 0.9 0.00068 19.0 0.0 2.1 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 VBB31333.1 - 0.018 14.6 2.3 4.1 6.9 1.6 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 VBB31333.1 - 0.031 14.3 5.0 2.1 8.4 0.2 3.4 2 1 1 3 3 3 0 Dynamin family AAA_22 PF13401.6 VBB31333.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 VBB31333.1 - 0.036 14.6 0.6 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 VBB31333.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 VBB31333.1 - 0.087 12.0 0.0 0.087 12.0 0.0 2.3 2 2 1 3 3 3 0 G-protein alpha subunit DUF3552 PF12072.8 VBB31333.1 - 0.71 9.3 14.5 1.3 8.4 14.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TetR_C_24 PF17932.1 VBB31333.1 - 4.5 7.6 5.8 7.2 6.9 4.7 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 VBB31335.1 - 9.2e-70 235.0 0.1 1.4e-69 234.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31335.1 - 7.5e-41 140.1 0.0 1.1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 VBB31335.1 - 8.5e-40 134.8 0.1 4.2e-21 74.9 0.2 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 VBB31335.1 - 4.8e-08 32.7 0.0 2.1e-07 30.6 0.0 2.0 1 1 2 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 VBB31335.1 - 2.6e-05 23.2 0.0 4.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RhoGAP PF00620.27 VBB31336.1 - 2.1e-24 86.1 0.1 5.4e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain PDZ PF00595.24 VBB31336.1 - 4.4e-07 30.2 0.0 8.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 VBB31336.1 - 3.1e-06 27.4 0.0 7.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 VBB31336.1 - 0.00081 19.2 0.1 0.0029 17.4 0.1 2.0 2 0 0 2 2 2 1 PDZ domain Miga PF10265.9 VBB31336.1 - 4.2 6.2 5.6 6 5.7 5.6 1.1 1 0 0 1 1 1 0 Mitoguardin Meckelin PF09773.9 VBB31337.1 - 8.6e-177 589.8 20.4 8.6e-177 589.8 20.4 1.7 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) DUF1053 PF06327.14 VBB31337.1 - 0.028 15.0 0.1 0.1 13.2 0.1 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) cEGF PF12662.7 VBB31337.1 - 0.11 12.4 2.8 0.57 10.2 2.8 2.4 1 1 0 1 1 1 0 Complement Clr-like EGF-like TLE_N PF03920.15 VBB31338.1 - 2.2e-46 157.2 13.9 3.8e-46 156.4 13.9 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 VBB31338.1 - 3.7e-13 49.7 14.3 0.0056 17.5 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31338.1 - 3.7e-06 27.1 0.3 0.095 13.0 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB31338.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain APG17 PF04108.12 VBB31338.1 - 0.1 11.7 4.6 0.15 11.1 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 EST1_DNA_bind PF10373.9 VBB31339.1 - 0.018 14.5 9.2 0.012 15.2 3.9 2.9 3 1 0 3 3 3 0 Est1 DNA/RNA binding domain PIN_4 PF13638.6 VBB31339.1 - 0.22 11.8 2.5 0.53 10.6 0.1 2.4 2 0 0 2 2 2 0 PIN domain Ig_3 PF13927.6 VBB31341.1 - 6.6e-37 126.0 1.0 1.4e-14 54.4 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 VBB31341.1 - 1.4e-36 124.4 0.0 4e-13 49.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 VBB31341.1 - 1.7e-23 82.6 0.1 1.7e-08 34.5 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB31341.1 - 2.3e-20 72.7 0.4 3.2e-08 33.8 0.0 4.0 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 VBB31341.1 - 3.5e-17 62.5 1.3 3.1e-06 27.3 0.0 4.9 3 2 0 3 3 3 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 VBB31341.1 - 9.3e-05 22.4 0.1 0.61 10.2 0.0 3.1 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 VBB31341.1 - 0.00041 20.4 3.9 0.13 12.4 0.0 3.5 4 1 1 5 5 5 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 VBB31341.1 - 0.00078 19.2 0.1 0.17 11.7 0.0 3.0 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 VBB31341.1 - 0.0043 16.6 0.0 3.6 7.2 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.15 VBB31341.1 - 0.0044 17.4 0.2 0.056 13.8 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_Tie2_1 PF10430.9 VBB31341.1 - 0.011 16.2 0.1 0.45 11.0 0.0 3.0 3 0 0 3 3 3 0 Tie-2 Ig-like domain 1 Aconitase PF00330.20 VBB31342.1 - 1.2e-89 301.5 0.0 1.4e-89 301.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) zf-CCCH PF00642.24 VBB31344.1 - 5.2e-11 42.2 22.3 5.7e-06 26.1 2.8 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB31344.1 - 1.9e-07 30.9 27.0 1.9e-05 24.5 5.2 3.8 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 VBB31344.1 - 0.00019 21.6 11.4 0.0022 18.2 2.5 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 VBB31344.1 - 0.00027 20.6 3.2 0.00027 20.6 3.2 3.6 4 0 0 4 4 4 2 CCCH-type zinc finger Torus PF16131.5 VBB31344.1 - 0.012 16.3 20.1 0.018 15.7 1.3 3.7 2 1 2 4 4 4 0 Torus domain DUF3402 PF11882.8 VBB31345.1 - 1.1e-87 295.1 14.1 1.8e-49 169.1 4.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) TTR-52 PF01060.23 VBB31347.1 - 0.04 14.6 0.6 0.15 12.8 0.1 2.2 2 1 0 2 2 2 0 Transthyretin-like family Bromodomain PF00439.25 VBB31348.1 - 5.8e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ALGX PF16822.5 VBB31348.1 - 0.98 9.0 4.1 6.9 6.3 0.1 2.4 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX OMPdecase PF00215.24 VBB31349.1 - 2.9e-45 154.6 0.2 4.2e-45 154.1 0.2 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 VBB31349.1 - 1.8e-12 47.1 0.0 3.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HERV-K_REC PF15695.5 VBB31349.1 - 0.08 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 U-box PF04564.15 VBB31350.1 - 0.11 12.6 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 U-box domain SLATT_1 PF18181.1 VBB31350.1 - 0.11 12.4 1.5 0.3 11.0 1.5 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2052 PF09747.9 VBB31351.1 - 1.5e-37 129.7 19.2 1.5e-37 129.7 19.2 1.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DUF4239 PF14023.6 VBB31351.1 - 0.089 12.5 1.4 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Ribosomal_L18A PF01775.17 VBB31352.1 - 4.9e-53 178.4 1.4 6.2e-53 178.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF5496 PF17600.2 VBB31352.1 - 0.039 14.0 0.3 0.13 12.3 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5496) ANAPC4_WD40 PF12894.7 VBB31353.1 - 0.00022 21.5 0.1 0.95 9.8 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB31353.1 - 0.016 16.1 0.0 3.3 8.7 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3069 PF11269.8 VBB31353.1 - 6.3 7.1 8.2 17 5.7 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) Ion_trans_2 PF07885.16 VBB31354.1 - 2.1e-13 50.0 8.8 4.6e-11 42.5 3.2 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 VBB31354.1 - 3.2 6.9 10.6 4.1 6.6 3.8 2.6 1 1 2 3 3 3 0 Ion transport protein Ion_trans_2 PF07885.16 VBB31355.1 - 0.00012 21.9 5.2 0.00031 20.7 0.2 2.2 2 0 0 2 2 2 2 Ion channel Peptidase_M16 PF00675.20 VBB31356.1 - 1.4e-47 161.4 0.2 2.8e-47 160.4 0.2 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 VBB31356.1 - 1.5e-29 103.4 0.0 1.4e-26 93.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain 7tm_1 PF00001.21 VBB31356.1 - 1.1e-08 34.8 17.2 1.5e-08 34.3 17.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 VBB31356.1 - 0.00037 19.9 17.2 0.0018 17.6 17.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF725 PF05267.12 VBB31356.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF725) LIDHydrolase PF10230.9 VBB31357.1 - 2e-39 135.8 0.3 2.6e-32 112.4 0.1 2.1 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 VBB31357.1 - 0.019 15.6 0.0 0.049 14.2 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 VBB31357.1 - 0.059 12.6 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 VBB31357.1 - 0.093 12.4 0.4 0.37 10.5 0.4 1.8 1 1 0 1 1 1 0 PGAP1-like protein JAB PF01398.21 VBB31358.1 - 4.4e-32 110.5 0.0 1e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 VBB31358.1 - 3.8e-14 53.1 0.9 3.8e-14 53.1 0.9 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 VBB31358.1 - 4.6e-06 26.4 0.0 7.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SAM_1 PF00536.30 VBB31358.1 - 0.047 14.1 0.4 0.12 12.8 0.4 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PGM_PMM_II PF02879.16 VBB31358.1 - 0.067 13.8 0.0 1 10.0 0.0 2.4 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Folate_carrier PF01770.18 VBB31359.1 - 5.4e-104 348.2 30.5 6.6e-104 347.9 30.5 1.0 1 0 0 1 1 1 1 Reduced folate carrier DUF1505 PF07403.11 VBB31359.1 - 0.055 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Herpes_U15 PF05613.11 VBB31359.1 - 4.7 8.0 9.0 7.5 7.3 0.5 2.8 3 0 0 3 3 3 0 Human herpesvirus U15 protein Nucleotid_trans PF03407.16 VBB31360.1 - 4.4e-06 26.8 0.0 5.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RabGAP-TBC PF00566.18 VBB31361.1 - 2e-40 138.7 0.2 2e-40 138.7 0.2 2.8 3 1 0 3 3 3 1 Rab-GTPase-TBC domain MINDY_DUB PF04424.13 VBB31361.1 - 0.057 13.4 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 MINDY deubiquitinase TUDOR PF00567.24 VBB31362.1 - 5.4e-09 36.1 0.0 1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Tudor domain RRM_1 PF00076.22 VBB31362.1 - 2.1e-06 27.5 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 VBB31363.1 - 1.5e-20 72.4 75.6 0.0065 16.9 3.4 9.8 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB31363.1 - 5.6e-19 67.2 78.2 0.0028 18.3 0.7 10.7 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB31363.1 - 6.5e-07 29.5 65.0 0.00096 19.5 1.5 9.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 VBB31363.1 - 0.0063 16.8 1.2 0.0063 16.8 1.2 8.4 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 VBB31363.1 - 0.014 15.2 0.7 0.014 15.2 0.7 9.1 10 1 0 10 10 10 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 VBB31363.1 - 0.71 10.2 0.1 0.58 10.5 2.6 6.4 4 3 3 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 VBB31363.1 - 1.1 9.1 0.0 1.1 9.1 0.0 7.1 6 2 2 8 8 8 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 VBB31363.1 - 6.8 7.1 51.5 2.7 8.4 1.2 7.7 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 VBB31366.1 - 6.5e-47 160.1 0.1 1.3e-22 80.5 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31366.1 - 7.7e-26 90.9 0.0 9.1e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31366.1 - 7.2e-14 51.4 0.3 2.9e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase ABC1 PF03109.16 VBB31366.1 - 9.9e-06 25.7 0.2 0.16 12.1 0.1 3.0 3 0 0 3 3 3 2 ABC1 family Stn1_C PF12659.7 VBB31366.1 - 0.0014 18.6 0.9 3.4 7.6 0.0 4.1 4 0 0 4 4 4 1 Telomere capping C-terminal wHTH DUF1972 PF09314.11 VBB31366.1 - 0.057 13.0 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1972) I-set PF07679.16 VBB31367.1 - 8.9e-56 185.9 0.0 6.2e-20 71.1 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB31367.1 - 4.4e-40 136.2 0.3 1.3e-12 48.1 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 VBB31367.1 - 2.7e-27 94.9 0.0 3.1e-08 33.8 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB31367.1 - 3.3e-17 62.4 1.4 4.7e-06 26.7 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 VBB31367.1 - 2.4e-08 33.9 1.1 0.052 13.6 0.0 4.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain DDHD PF02862.17 VBB31367.1 - 0.018 15.2 4.9 0.85 9.7 0.3 2.8 2 0 0 2 2 2 0 DDHD domain Serinc PF03348.15 VBB31367.1 - 9.5 5.0 9.6 9.3 5.0 0.3 2.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) His_Phos_2 PF00328.22 VBB31368.1 - 5.5e-28 98.4 1.4 2.8e-26 92.8 1.4 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CsoSCA PF08936.10 VBB31368.1 - 0.035 12.8 0.1 0.067 11.8 0.1 1.4 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase FliW PF02623.15 VBB31368.1 - 0.07 13.0 0.7 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 FliW protein Maelstrom PF13017.6 VBB31369.1 - 3.1e-22 79.3 0.1 1.2e-16 61.0 0.0 2.2 2 0 0 2 2 2 2 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 VBB31369.1 - 0.013 16.1 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 VBB31369.1 - 0.66 10.4 4.8 0.5 10.8 0.6 2.8 2 1 0 2 2 2 0 HMG (high mobility group) box Peptidase_S64 PF08192.11 VBB31370.1 - 0.0051 15.4 2.1 0.016 13.8 0.2 2.1 2 0 0 2 2 2 1 Peptidase family S64 BRCT_assoc PF12820.7 VBB31370.1 - 0.0061 16.4 3.1 0.011 15.6 0.1 2.3 2 0 0 2 2 2 1 Serine-rich domain associated with BRCT MatP PF06303.12 VBB31370.1 - 0.0082 16.7 0.6 0.03 14.9 0.2 2.2 2 0 0 2 2 2 1 MatP N-terminal domain TetR_C_4 PF08359.11 VBB31370.1 - 0.017 15.3 0.9 0.062 13.4 0.4 2.2 2 1 0 2 2 2 0 YsiA-like protein, C-terminal region Aa_trans PF01490.18 VBB31371.1 - 1.8e-75 254.2 29.8 3.2e-75 253.4 29.8 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ANAPC4_WD40 PF12894.7 VBB31371.1 - 3.3e-18 65.8 0.2 6.5e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 VBB31371.1 - 3.8e-09 36.3 0.1 3.9e-08 33.0 0.1 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PSI_PSAK PF01241.18 VBB31371.1 - 0.0007 19.6 0.8 0.0025 17.8 0.8 2.0 1 0 0 1 1 1 1 Photosystem I psaG / psaK PRT_C PF08372.10 VBB31371.1 - 0.048 13.4 0.7 0.13 12.0 0.7 1.7 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DSPc PF00782.20 VBB31372.1 - 1.3e-14 54.1 0.2 5.6e-14 52.1 0.0 2.0 1 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Spt5_N PF11942.8 VBB31372.1 - 0.095 13.7 10.9 2.5 9.1 3.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GET2 PF08690.10 VBB31372.1 - 0.88 9.2 15.6 0.21 11.2 7.9 2.1 1 1 1 2 2 2 0 GET complex subunit GET2 SRP72 PF08492.12 VBB31372.1 - 1.8 9.1 13.4 1.1 9.7 0.1 2.8 2 1 0 2 2 2 0 SRP72 RNA-binding domain Jiv90 PF14901.6 VBB31373.1 - 2.6e-36 123.6 7.0 2.6e-36 123.6 7.0 2.3 2 1 0 2 2 2 1 Cleavage inducing molecular chaperone DnaJ PF00226.31 VBB31373.1 - 2.6e-16 59.5 0.6 1.9e-14 53.5 0.2 2.6 2 0 0 2 2 2 2 DnaJ domain Ank_2 PF12796.7 VBB31376.1 - 2.3e-28 98.6 9.7 6.6e-10 39.4 0.2 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB31376.1 - 5.6e-25 87.1 6.7 2e-08 34.3 0.2 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 VBB31376.1 - 1.5e-24 85.3 12.6 0.0024 18.2 0.3 9.1 8 1 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 VBB31376.1 - 2.2e-24 85.5 13.4 5.9e-06 26.7 0.1 6.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB31376.1 - 1.1e-17 62.3 12.9 0.0032 17.8 0.1 9.7 9 0 0 9 9 9 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 VBB31376.1 - 7.9e-08 32.0 21.4 5.1e-05 23.1 14.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Flag1_repress PF03614.13 VBB31376.1 - 0.021 14.6 1.2 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Repressor of phase-1 flagellin Prok-RING_4 PF14447.6 VBB31376.1 - 0.026 14.4 19.2 0.14 12.0 14.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RecR PF02132.15 VBB31376.1 - 0.19 11.3 6.6 0.89 9.2 2.5 2.6 2 0 0 2 2 2 0 RecR protein YejG PF13989.6 VBB31376.1 - 0.27 11.7 3.2 1.5 9.3 1.0 2.5 2 0 0 2 2 2 0 YejG-like protein zf-RING_UBOX PF13445.6 VBB31376.1 - 1.8 8.7 12.8 2.6 8.1 8.1 3.2 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 VBB31376.1 - 9.6 6.3 21.5 2 8.4 16.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB31376.1 - 9.7 6.1 23.9 2.4 8.0 15.5 3.2 3 1 1 4 4 3 0 Zinc finger, C3HC4 type (RING finger) RMP PF14996.6 VBB31377.1 - 1.4 9.1 7.0 0.21 11.8 1.5 2.4 1 1 1 2 2 2 0 Retinal Maintenance MFS_1 PF07690.16 VBB31379.1 - 4e-35 121.4 31.3 4.5e-22 78.4 15.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SpecificRecomb PF10136.9 VBB31379.1 - 0.24 9.7 3.9 0.59 8.4 3.9 1.6 1 0 0 1 1 1 0 Site-specific recombinase SH2 PF00017.24 VBB31380.1 - 9.5e-14 51.3 0.0 3.9e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 SH2 domain SH3_1 PF00018.28 VBB31380.1 - 3.4e-06 26.6 0.0 7.6e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB31380.1 - 0.00026 20.8 0.0 0.00074 19.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 VBB31380.1 - 0.00051 20.5 0.1 0.0018 18.8 0.1 2.0 1 0 0 1 1 1 1 PH domain RasGAP PF00616.19 VBB31380.1 - 0.0017 18.1 0.1 0.0047 16.6 0.1 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase SH3_2 PF07653.17 VBB31380.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain MADF_DNA_bdg PF10545.9 VBB31381.1 - 2.4e-13 50.2 0.1 7.1e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB31381.1 - 6.2e-06 26.5 0.1 2.9e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Lon_2 PF13337.6 VBB31381.1 - 0.074 11.6 0.3 0.11 11.1 0.3 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease TIP120 PF08623.10 VBB31381.1 - 0.14 11.9 0.6 0.26 11.0 0.6 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) PG_binding_2 PF08823.11 VBB31384.1 - 0.12 12.7 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain ERF PF04404.12 VBB31384.1 - 4.2 7.2 10.7 1.9 8.3 7.0 2.2 2 0 0 2 2 2 0 ERF superfamily Thiolase_N PF00108.23 VBB31385.1 - 1.3e-19 70.6 0.9 1.3e-18 67.4 0.9 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain SCP2 PF02036.17 VBB31385.1 - 9.1e-18 64.6 0.1 2.1e-17 63.4 0.1 1.6 2 0 0 2 2 2 1 SCP-2 sterol transfer family Thiolase_C PF02803.18 VBB31385.1 - 1.6e-11 43.9 0.5 1.4e-10 40.9 0.0 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain Alkyl_sulf_C PF14864.6 VBB31385.1 - 0.00041 20.6 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ketoacyl-synt PF00109.26 VBB31385.1 - 0.00049 19.7 0.5 0.0011 18.6 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 VBB31385.1 - 0.0054 16.7 0.2 0.95 9.5 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 VBB31385.1 - 0.0067 15.2 0.3 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 VBB31385.1 - 0.036 13.9 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Laminin_G_2 PF02210.24 VBB31387.1 - 2.5e-22 79.8 0.3 3.4e-08 34.1 0.1 4.3 4 0 0 4 4 4 3 Laminin G domain Laminin_G_1 PF00054.23 VBB31387.1 - 6.7e-08 32.8 0.0 0.99 9.6 0.0 4.8 3 1 0 3 3 3 3 Laminin G domain CMAS PF02353.20 VBB31389.1 - 1.5e-76 257.3 0.0 2e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 VBB31389.1 - 1.9e-09 38.1 0.0 3.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB31389.1 - 1e-08 35.8 0.0 2.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB31389.1 - 7.4e-08 32.4 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB31389.1 - 1.5e-06 28.8 0.0 2.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 VBB31389.1 - 0.00045 19.8 0.0 0.00073 19.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 VBB31389.1 - 0.00086 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB31389.1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 VBB31389.1 - 0.0052 16.2 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 VBB31389.1 - 0.0059 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 VBB31389.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_10 PF05971.12 VBB31389.1 - 0.064 12.6 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 RNA methyltransferase Ldh_2 PF02615.14 VBB31390.1 - 1.1e-104 350.2 0.5 1.4e-104 349.8 0.5 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ala_racemase_C PF00842.21 VBB31390.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain UDG PF03167.19 VBB31392.1 - 3e-23 82.5 0.0 5.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RNA_pol_Rpb2_6 PF00562.28 VBB31394.1 - 1.6e-128 429.1 0.8 2.5e-128 428.5 0.8 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 VBB31394.1 - 1.3e-54 184.8 0.0 1.6e-45 155.1 0.0 2.3 1 1 1 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 VBB31394.1 - 3e-54 183.6 0.3 1.8e-53 181.0 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 VBB31394.1 - 6.4e-33 113.0 0.1 2.4e-32 111.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 VBB31394.1 - 5.4e-25 87.4 0.0 1.2e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 VBB31394.1 - 3.6e-24 84.8 0.5 7.8e-24 83.7 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 VBB31394.1 - 2.5e-16 60.0 0.3 6.2e-16 58.7 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 C1_2 PF03107.16 VBB31394.1 - 1 9.7 4.2 7.7 6.9 3.9 2.4 1 1 1 2 2 2 0 C1 domain RWD PF05773.22 VBB31395.1 - 3.9e-19 69.1 0.0 6.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 VBB31395.1 - 0.033 14.7 8.6 0.093 13.2 8.2 1.9 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 M20_dimer PF07687.14 VBB31396.1 - 6.8e-21 74.2 0.1 1.1e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 VBB31396.1 - 1.6e-20 73.7 0.1 2.8e-19 69.7 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 VBB31396.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 IL17R_D_N PF16742.5 VBB31397.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CLN3 PF02487.17 VBB31398.1 - 1.2e-28 100.3 9.2 1.6e-21 76.8 4.8 2.0 1 1 1 2 2 2 2 CLN3 protein WW PF00397.26 VBB31400.1 - 2.3e-11 43.6 10.0 6.3e-10 39.0 1.7 2.7 2 0 0 2 2 2 2 WW domain PID_2 PF14719.6 VBB31401.1 - 2.6e-81 271.8 1.2 3.6e-81 271.4 1.2 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Microtub_bind PF13931.6 VBB31401.1 - 0.041 14.3 0.4 0.12 12.7 0.4 1.8 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding SH3_2 PF07653.17 VBB31402.1 - 2.2e-09 36.8 0.1 3.6e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB31402.1 - 4.6e-08 32.6 0.0 7.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB31402.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 VBB31402.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF4637 PF15470.6 VBB31402.1 - 5.4 6.7 8.6 20 4.8 2.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4637) HTH_psq PF05225.16 VBB31403.1 - 5.8e-10 38.8 1.9 0.0034 17.1 0.4 3.6 3 0 0 3 3 3 2 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 VBB31403.1 - 1e-05 24.8 0.1 0.67 9.4 0.1 4.0 4 0 0 4 4 4 2 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 VBB31403.1 - 0.02 14.6 0.4 0.097 12.4 0.2 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_Tc5 PF03221.16 VBB31403.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 VBB31403.1 - 0.093 12.9 0.1 1.8 8.7 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 VBB31403.1 - 0.17 11.9 0.1 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix PRC2_HTH_1 PF18118.1 VBB31403.1 - 0.32 11.8 5.4 1.7 9.5 0.5 3.4 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain RBD-FIP PF09457.10 VBB31404.1 - 1.5e-08 34.4 0.9 2.2e-08 33.9 0.9 1.3 1 0 0 1 1 1 1 FIP domain DUF630 PF04783.12 VBB31404.1 - 0.048 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF630) Nucleopor_Nup85 PF07575.13 VBB31405.1 - 4.2e-111 372.3 5.6 5.4e-111 371.9 5.6 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin CRAL_TRIO_N PF03765.15 VBB31405.1 - 0.059 13.6 0.2 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Actin PF00022.19 VBB31406.1 - 3e-47 161.1 0.0 3.2e-38 131.4 0.0 2.5 1 1 1 2 2 2 2 Actin Sua5_yciO_yrdC PF01300.18 VBB31407.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Telomere recombination DUF349 PF03993.12 VBB31407.1 - 0.15 12.3 0.1 0.2 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) zf-H2C2_2 PF13465.6 VBB31408.1 - 2e-20 72.2 24.4 2.6e-07 30.7 2.6 5.9 5 1 0 5 5 5 5 Zinc-finger double domain Homeodomain PF00046.29 VBB31408.1 - 4.9e-16 58.3 1.3 1.4e-15 56.9 0.4 2.1 2 0 0 2 2 2 1 Homeodomain zf-C2H2 PF00096.26 VBB31408.1 - 5.3e-15 54.9 38.4 0.00017 21.9 4.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB31408.1 - 1.7e-07 31.5 37.5 0.13 13.2 3.7 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB31408.1 - 3.4e-05 24.0 33.9 0.014 15.7 3.6 4.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding Homeobox_KN PF05920.11 VBB31408.1 - 0.00088 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_6 PF13912.6 VBB31408.1 - 0.0023 17.9 1.2 0.0023 17.9 1.2 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 VBB31408.1 - 0.0023 18.2 5.3 0.0023 18.2 5.3 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 VBB31408.1 - 0.0071 17.1 5.9 0.98 10.2 1.3 2.7 2 0 0 2 2 2 2 zinc-ribbon family zf-C2H2_2 PF12756.7 VBB31408.1 - 1.6 9.1 19.9 0.13 12.6 0.7 3.7 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.7 VBB31408.1 - 3.3 7.7 14.4 0.86 9.6 0.2 4.6 4 1 0 4 4 4 0 Transposase zinc-ribbon domain CpXC PF14353.6 VBB31408.1 - 4.4 7.4 14.4 6.7 6.8 0.1 4.7 4 1 0 4 4 4 0 CpXC protein CENP-B_dimeris PF09026.10 VBB31409.1 - 3 8.3 16.5 3.5 8.1 16.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Solute_trans_a PF03619.16 VBB31410.1 - 2.9e-23 82.7 19.6 4.1e-23 82.3 19.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4718 PF15842.5 VBB31410.1 - 0.082 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Ninjurin PF04923.12 VBB31410.1 - 0.67 9.9 3.8 1 9.3 0.2 2.7 2 1 0 2 2 2 0 Ninjurin SLATT_6 PF18169.1 VBB31410.1 - 1.9 8.1 5.3 3.8 7.1 0.6 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Pyr_redox_2 PF07992.14 VBB31411.1 - 9.4e-44 149.8 0.0 1.6e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 VBB31411.1 - 3.2e-22 79.3 8.8 4e-15 56.3 0.0 3.2 2 1 1 3 3 3 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 VBB31411.1 - 4.8e-08 33.5 0.0 1.8e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 VBB31411.1 - 0.00012 20.9 0.1 0.013 14.2 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein Deltameth_res PF16020.5 VBB31411.1 - 0.043 13.7 1.9 0.053 13.4 0.3 2.0 2 0 0 2 2 2 0 Deltamethrin resistance Amino_oxidase PF01593.24 VBB31411.1 - 0.058 12.7 0.0 0.72 9.1 0.0 2.0 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase DUF2525 PF10733.9 VBB31411.1 - 0.069 13.4 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) K_oxygenase PF13434.6 VBB31411.1 - 0.12 11.5 0.0 0.38 9.9 0.0 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) PBP PF01161.20 VBB31412.1 - 9.1e-22 77.8 0.1 1.5e-21 77.1 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.16 VBB31414.1 - 9.2e-35 120.2 34.9 9.2e-35 120.2 34.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ubiquitin PF00240.23 VBB31414.1 - 3.9e-10 39.3 0.1 7.6e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 VBB31414.1 - 0.0015 18.3 0.3 0.0034 17.2 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 VBB31414.1 - 0.049 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 VBB31414.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain WD40 PF00400.32 VBB31415.1 - 2.5e-17 62.9 8.2 7e-07 29.8 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31415.1 - 4.9e-08 33.2 0.4 0.063 13.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 VBB31415.1 - 2e-05 24.2 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 VBB31415.1 - 0.0023 17.0 0.6 6.6 5.6 0.0 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_trans_CmpB PF06541.11 VBB31416.1 - 0.08 13.2 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative ABC-transporter type IV PAS_11 PF14598.6 VBB31417.1 - 8.1e-22 77.5 0.2 1.4e-15 57.4 0.2 2.3 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 VBB31417.1 - 6.6e-17 61.6 0.0 1.8e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 VBB31417.1 - 2.1e-13 50.3 0.0 2.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 VBB31417.1 - 7.2e-08 32.6 0.0 0.00064 19.9 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 VBB31417.1 - 2.2e-05 24.7 0.0 0.035 14.3 0.0 2.9 2 1 1 3 3 3 2 PAS fold Thiolase_N PF00108.23 VBB31418.1 - 1.3e-19 70.6 0.9 1.3e-18 67.4 0.9 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain SCP2 PF02036.17 VBB31418.1 - 9.1e-18 64.6 0.1 2.1e-17 63.4 0.1 1.6 2 0 0 2 2 2 1 SCP-2 sterol transfer family Thiolase_C PF02803.18 VBB31418.1 - 1.6e-11 43.9 0.5 1.4e-10 40.9 0.0 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain Alkyl_sulf_C PF14864.6 VBB31418.1 - 0.00041 20.6 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ketoacyl-synt PF00109.26 VBB31418.1 - 0.00049 19.7 0.5 0.0011 18.6 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 VBB31418.1 - 0.0054 16.7 0.2 0.95 9.5 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 VBB31418.1 - 0.0067 15.2 0.3 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 VBB31418.1 - 0.036 13.9 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III An_peroxidase PF03098.15 VBB31419.1 - 1.2e-157 525.7 0.0 1.5e-157 525.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase BTB PF00651.31 VBB31423.1 - 2e-21 76.3 0.4 4.7e-21 75.1 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 VBB31423.1 - 2.4e-19 69.5 0.9 2.4e-19 69.5 0.9 1.8 2 0 0 2 2 2 1 MATH domain Ribosomal_S24e PF01282.19 VBB31424.1 - 1.8e-33 114.3 0.0 3.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Clathrin PF00637.20 VBB31425.1 - 0.031 14.1 0.4 0.049 13.5 0.4 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS MazE_antitoxin PF04014.18 VBB31427.1 - 0.0078 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin BLM10_mid PF16507.5 VBB31428.1 - 9.1e-71 239.1 10.2 4.9e-68 230.1 10.2 3.6 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 VBB31428.1 - 1.1e-34 118.2 0.1 4.9e-34 116.1 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 VBB31428.1 - 0.0021 18.5 1.0 4.4 7.9 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 VBB31428.1 - 0.0095 16.1 0.1 0.25 11.7 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat adh_short PF00106.25 VBB31430.1 - 1.5e-29 102.9 0.1 6.1e-24 84.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 VBB31430.1 - 1.1e-26 93.9 0.0 1.5e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB31430.1 - 1.1e-08 35.3 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 VBB31430.1 - 8.3e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 VBB31430.1 - 0.00084 18.6 0.0 0.0015 17.7 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 VBB31430.1 - 0.0012 18.4 0.2 0.0031 17.0 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AAA PF00004.29 VBB31431.1 - 1e-35 123.0 0.0 2.3e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rogdi_lz PF10259.9 VBB31431.1 - 3.9e-14 52.8 0.5 7.1e-14 51.9 0.5 1.6 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein RuvB_N PF05496.12 VBB31431.1 - 1.4e-07 31.4 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 VBB31431.1 - 7e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 VBB31431.1 - 8.8e-06 25.8 0.0 2.5e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB31431.1 - 1e-05 26.0 0.4 8.3e-05 23.0 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 VBB31431.1 - 4.6e-05 23.7 1.9 0.2 12.0 0.0 3.3 1 1 2 3 3 3 2 AAA domain NACHT PF05729.12 VBB31431.1 - 6e-05 23.0 0.4 0.13 12.2 0.0 2.7 1 1 1 2 2 2 2 NACHT domain AAA_2 PF07724.14 VBB31431.1 - 0.00045 20.4 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 VBB31431.1 - 0.00064 19.7 0.7 0.0035 17.3 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 VBB31431.1 - 0.00076 19.5 0.0 0.0025 17.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain Bac_DnaA PF00308.18 VBB31431.1 - 0.00098 19.0 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_7 PF12775.7 VBB31431.1 - 0.0024 17.4 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 VBB31431.1 - 0.003 17.9 0.0 0.0085 16.5 0.0 1.9 1 1 0 1 1 1 1 RNA helicase TsaE PF02367.17 VBB31431.1 - 0.0037 17.3 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 VBB31431.1 - 0.0041 16.4 0.0 0.077 12.2 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain Sigma54_activat PF00158.26 VBB31431.1 - 0.0047 16.6 0.0 1.4 8.6 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 VBB31431.1 - 0.0059 17.2 0.0 0.016 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 VBB31431.1 - 0.0059 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 VBB31431.1 - 0.0073 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 VBB31431.1 - 0.0074 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 VBB31431.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 VBB31431.1 - 0.015 14.7 0.6 0.98 8.7 0.0 3.1 2 1 1 3 3 3 0 KaiC CheF-arch PF04283.12 VBB31431.1 - 0.02 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea AAA_17 PF13207.6 VBB31431.1 - 0.024 15.0 0.0 0.13 12.7 0.0 2.3 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 VBB31431.1 - 0.027 13.8 0.0 0.07 12.5 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 VBB31431.1 - 0.028 13.5 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_lid_3 PF17862.1 VBB31431.1 - 0.034 14.0 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain AAA_19 PF13245.6 VBB31431.1 - 0.034 14.5 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 VBB31431.1 - 0.036 14.0 0.0 5 7.0 0.0 3.6 4 0 0 4 4 4 0 NTPase AAA_25 PF13481.6 VBB31431.1 - 0.042 13.4 0.0 0.4 10.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 VBB31431.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 VBB31432.1 - 5.5e-60 203.0 0.0 8.1e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31432.1 - 1.6e-31 109.6 0.0 2.3e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31432.1 - 1.7e-05 24.3 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB31432.1 - 0.0011 17.8 0.0 0.0022 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB31432.1 - 0.0031 16.6 0.0 0.25 10.3 0.0 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 FTA2 PF13095.6 VBB31432.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 VBB31432.1 - 0.016 15.2 0.0 4.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 VBB31432.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB31432.1 - 0.021 13.8 0.0 0.049 12.6 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain CAF1C_H4-bd PF12265.8 VBB31433.1 - 3.2e-29 101.0 1.4 2.4e-28 98.2 0.5 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 VBB31433.1 - 4.5e-26 90.6 14.3 1.8e-07 31.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 VBB31433.1 - 3.1e-06 27.2 1.1 0.023 14.6 0.1 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 VBB31433.1 - 1.4e-05 25.3 0.2 0.012 15.9 0.0 3.7 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Isy1 PF06246.12 VBB31434.1 - 8.9e-82 274.5 9.9 1e-81 274.3 9.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Sushi PF00084.20 VBB31435.1 - 8.5e-08 32.7 8.7 7.6e-05 23.2 0.5 3.9 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) GT87 PF09594.10 VBB31435.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 Vezatin PF12632.7 VBB31436.1 - 0.012 15.1 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes KxDL PF10241.9 VBB31439.1 - 1.1e-24 86.6 1.2 1.3e-24 86.2 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein TssC PF17541.2 VBB31439.1 - 0.018 13.9 1.2 0.021 13.7 1.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Atg14 PF10186.9 VBB31439.1 - 0.075 12.1 3.1 0.079 12.0 3.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1043 PF06295.12 VBB31439.1 - 0.14 12.1 3.3 7.3 6.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) zf-CCHC_3 PF13917.6 VBB31440.1 - 1.2e-05 25.2 0.7 1.2e-05 25.2 0.7 1.8 2 1 0 2 2 2 1 Zinc knuckle Spt5_N PF11942.8 VBB31440.1 - 0.64 11.0 6.2 0.85 10.6 6.2 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Neur_chan_memb PF02932.16 VBB31440.1 - 0.94 9.5 3.4 0.97 9.4 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-CCHC PF00098.23 VBB31440.1 - 1.3 9.3 6.2 5.6 7.2 6.2 2.2 1 1 0 1 1 1 0 Zinc knuckle I-set PF07679.16 VBB31441.1 - 1.8e-202 656.1 37.7 5.9e-25 87.2 0.0 16.9 16 1 0 16 16 16 15 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB31441.1 - 3e-116 380.2 6.7 2.7e-13 50.3 0.1 15.5 15 0 0 15 15 15 14 Immunoglobulin domain ig PF00047.25 VBB31441.1 - 1e-46 157.0 16.3 9.3e-08 32.1 0.0 13.0 14 0 0 14 14 13 9 Immunoglobulin domain Ig_2 PF13895.6 VBB31441.1 - 1.4e-43 147.1 0.9 1.1e-05 25.7 0.0 12.5 13 0 0 13 13 12 8 Immunoglobulin domain C2-set_2 PF08205.12 VBB31441.1 - 3.4e-20 71.9 5.7 0.073 13.1 0.0 12.2 13 1 1 14 14 13 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 VBB31441.1 - 4.5e-19 68.6 3.9 0.0003 21.0 0.0 9.8 10 2 0 10 10 10 3 Immunoglobulin V-set domain BiPBP_C PF06832.12 VBB31441.1 - 1.3e-16 60.4 0.0 0.32 11.1 0.0 12.0 14 0 0 14 14 12 1 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 VBB31441.1 - 4.1e-06 27.0 0.1 0.17 12.1 0.0 4.6 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 VBB31441.1 - 5.2e-06 25.9 0.0 0.043 13.4 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin domain Ig_5 PF16681.5 VBB31441.1 - 2.8e-05 24.4 12.9 3.8 8.0 0.0 8.5 9 0 0 9 9 7 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 VBB31441.1 - 0.00015 22.1 11.0 7.2 7.1 0.0 9.1 11 0 0 11 11 9 1 Immunoglobulin C1-set domain DUF4198 PF10670.9 VBB31441.1 - 0.00082 19.8 3.1 39 4.5 0.0 6.6 7 1 0 7 7 7 0 Domain of unknown function (DUF4198) DUF2505 PF10698.9 VBB31441.1 - 0.0034 17.5 0.7 5.6 7.0 0.1 4.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2505) PH PF00169.29 VBB31441.1 - 0.0038 17.7 0.2 0.016 15.7 0.2 2.1 1 0 0 1 1 1 1 PH domain DUF104 PF01954.16 VBB31441.1 - 0.0088 16.5 0.0 1.5 9.3 0.0 3.7 2 0 0 2 2 2 1 Protein of unknown function DUF104 Izumo-Ig PF16706.5 VBB31441.1 - 0.015 15.4 0.0 12 6.0 0.0 4.2 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Peptidase_A4 PF01828.17 VBB31441.1 - 0.045 13.2 8.7 0.05 13.1 0.1 4.2 6 0 0 6 6 6 0 Peptidase A4 family PH_10 PF15411.6 VBB31441.1 - 0.051 13.8 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain RhoGEF PF00621.20 VBB31441.1 - 0.08 13.2 0.8 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 RhoGEF domain C2-set PF05790.15 VBB31441.1 - 0.21 11.8 0.7 30 4.9 0.0 4.5 5 0 0 5 5 5 0 Immunoglobulin C2-set domain Chromo_2 PF18704.1 VBB31441.1 - 0.43 10.9 5.3 40 4.6 0.6 4.4 4 0 0 4 4 4 0 Chromatin organization modifier domain 2 LIM PF00412.22 VBB31443.1 - 4.9e-34 116.3 35.2 6.2e-14 52.0 3.9 3.2 3 0 0 3 3 3 3 LIM domain Ribosomal_L37ae PF01780.19 VBB31443.1 - 0.78 9.9 12.1 1 9.5 0.1 3.5 2 1 1 3 3 3 0 Ribosomal L37ae protein family DUF3236 PF11576.8 VBB31444.1 - 0.13 11.9 1.5 0.29 10.8 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Geminin PF07412.12 VBB31445.1 - 0.0058 16.4 1.5 0.0071 16.1 1.5 1.1 1 0 0 1 1 1 1 Geminin DUF3740 PF12548.8 VBB31445.1 - 0.15 12.5 2.1 2.4 8.6 0.1 2.1 1 1 0 2 2 2 0 Sulfatase protein BCS1_N PF08740.11 VBB31446.1 - 5.9e-36 124.2 0.3 7.8e-36 123.8 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 VBB31446.1 - 1.4e-18 67.6 0.0 2.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB31446.1 - 0.0092 16.4 0.0 0.029 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 VBB31446.1 - 0.0096 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 VBB31446.1 - 0.02 14.9 0.0 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 VBB31446.1 - 0.043 12.6 0.1 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase AAA_24 PF13479.6 VBB31446.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB31446.1 - 0.11 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 VBB31446.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 VBB31446.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 VBB31446.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase PF06745.13 VBB31446.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 VBB31446.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 VBB31446.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Polyoma_lg_T_C PF06431.11 VBB31446.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CAP_GLY PF01302.25 VBB31447.1 - 1e-47 160.0 1.9 1.2e-22 79.7 0.3 2.3 2 0 0 2 2 2 2 CAP-Gly domain Tup_N PF08581.10 VBB31447.1 - 0.006 16.9 6.3 0.006 16.9 6.3 7.4 3 3 2 6 6 6 2 Tup N-terminal GAS PF13851.6 VBB31447.1 - 0.007 15.7 105.8 0.45 9.8 24.7 5.1 2 2 2 4 4 4 3 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 VBB31447.1 - 0.37 11.2 37.9 1.1 9.6 4.7 5.2 2 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 VBB31447.1 - 2.4 8.6 91.2 0.018 15.5 25.0 5.5 1 1 4 6 6 6 0 Fez1 Filament PF00038.21 VBB31447.1 - 6.8 6.2 89.5 0.17 11.4 45.1 3.0 1 1 1 2 2 2 0 Intermediate filament protein TUDOR PF00567.24 VBB31448.1 - 1e-11 45.0 0.6 4.5e-05 23.5 0.0 2.9 2 0 0 2 2 2 2 Tudor domain CENP-B_dimeris PF09026.10 VBB31448.1 - 0.015 15.7 16.8 0.015 15.7 16.8 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain TFIIA PF03153.13 VBB31448.1 - 0.1 12.5 51.5 0.53 10.2 51.5 1.9 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCIP PF13324.6 VBB31448.1 - 0.3 10.7 9.5 0.83 9.2 9.5 1.7 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting zf-CCHC PF00098.23 VBB31448.1 - 0.94 9.7 7.4 0.16 12.1 0.8 2.8 2 0 0 2 2 2 0 Zinc knuckle RNA_pol_3_Rpc31 PF11705.8 VBB31448.1 - 2.9 8.1 21.9 0.13 12.5 15.5 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 rve PF00665.26 VBB31449.1 - 9.9e-05 22.5 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tyr_Deacylase PF02580.16 VBB31450.1 - 9.6e-50 168.9 0.0 1.1e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MFS_1 PF07690.16 VBB31452.1 - 7e-07 28.5 14.1 8.5e-07 28.2 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 VBB31452.1 - 2.9e-05 23.1 0.3 3.3e-05 22.9 0.3 1.0 1 0 0 1 1 1 1 MFS_1 like family Pkinase PF00069.25 VBB31453.1 - 5e-50 170.3 0.1 3.6e-36 124.9 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31453.1 - 3.3e-24 85.6 0.0 1.6e-18 66.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 VBB31453.1 - 3.1e-05 23.7 0.0 0.0013 18.4 0.0 2.9 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 VBB31453.1 - 0.00014 21.7 0.0 0.82 9.7 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat Kinase-like PF14531.6 VBB31453.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF621 PF04789.15 VBB31453.1 - 0.11 11.6 0.2 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) PQQ_3 PF13570.6 VBB31453.1 - 0.11 13.0 0.0 6.2 7.4 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain APH PF01636.23 VBB31453.1 - 0.2 11.5 0.3 0.45 10.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family pKID PF02173.17 VBB31454.1 - 2.4e-07 30.1 4.0 3.9e-07 29.4 4.0 1.5 1 0 0 1 1 1 1 pKID domain Glycos_transf_2 PF00535.26 VBB31455.1 - 2.6e-21 76.1 0.0 4.4e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 VBB31455.1 - 4.7e-05 23.0 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 VBB31455.1 - 0.00043 19.8 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3234 PF11572.8 VBB31455.1 - 0.14 12.4 0.0 0.85 9.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3234) HEXIM PF15313.6 VBB31456.1 - 9.6e-31 106.9 0.3 9.6e-31 106.9 0.3 1.8 2 0 0 2 2 2 1 Hexamethylene bis-acetamide-inducible protein Alpha-E PF04168.12 VBB31458.1 - 0.0053 16.6 0.1 0.01 15.7 0.1 1.3 1 1 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. DUF2274 PF10038.9 VBB31458.1 - 0.073 13.5 0.0 10 6.6 0.0 3.3 3 2 1 4 4 4 0 Protein of unknown function (DUF2274) DUF826 PF05696.11 VBB31458.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF826) DUF5354 PF17305.2 VBB31459.1 - 3.3e-14 53.1 0.8 4.7e-14 52.7 0.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5354) MTP18 PF10558.9 VBB31461.1 - 2.1e-17 63.6 3.8 3.1e-08 33.7 0.7 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Amino_oxidase PF01593.24 VBB31462.1 - 1e-76 259.1 0.0 1.4e-76 258.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 VBB31462.1 - 2.3e-09 37.3 1.5 5.1e-09 36.2 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 VBB31462.1 - 4e-09 36.7 0.1 9.5e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain HI0933_like PF03486.14 VBB31462.1 - 3.7e-06 25.9 1.0 0.00044 19.1 0.6 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 VBB31462.1 - 4.1e-06 26.2 0.2 7.3e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 VBB31462.1 - 4.4e-05 22.9 3.9 0.0011 18.2 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 VBB31462.1 - 7.5e-05 22.5 1.0 0.00056 19.6 0.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 VBB31462.1 - 0.00014 22.3 0.1 0.00014 22.3 0.1 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 VBB31462.1 - 0.00035 19.9 0.6 0.0011 18.2 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 VBB31462.1 - 0.0004 19.9 1.6 0.00068 19.1 1.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 VBB31462.1 - 0.00051 19.4 0.1 0.00098 18.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 VBB31462.1 - 0.00062 18.9 2.8 0.001 18.3 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain zf-CW PF07496.15 VBB31462.1 - 0.00088 19.3 1.6 0.0027 17.7 1.6 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger Pyr_redox_3 PF13738.6 VBB31462.1 - 0.01 15.1 0.0 0.091 12.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 VBB31462.1 - 0.044 12.8 0.1 3.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 VBB31462.1 - 0.05 12.7 1.0 0.082 12.0 0.6 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 VBB31463.1 - 1.1e-15 57.4 17.2 1.2e-15 57.3 11.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TssN PF17555.2 VBB31463.1 - 0.038 13.4 7.7 0.056 12.8 7.7 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN UPF0020 PF01170.18 VBB31465.1 - 7.9e-05 22.4 0.0 0.00023 20.9 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 VBB31465.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Pro-rich_19 PF15455.6 VBB31466.1 - 0.022 13.9 0.2 0.04 13.0 0.2 1.3 1 0 0 1 1 1 0 Proline-rich 19 ELFV_dehydrog_N PF02812.18 VBB31467.1 - 1.2e-55 186.9 0.0 2.1e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 VBB31467.1 - 1.2e-48 166.0 0.0 4.1e-45 154.4 0.0 2.1 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 VBB31467.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEAD PF00270.29 VBB31468.1 - 7.5e-39 133.3 0.1 1.7e-38 132.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31468.1 - 2.8e-27 95.3 0.5 7.9e-25 87.4 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB31468.1 - 4e-09 36.7 0.0 6.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KTI12 PF08433.10 VBB31468.1 - 2.3e-08 33.8 0.1 9.9e-08 31.7 0.0 1.9 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 VBB31468.1 - 7.2e-07 29.5 0.0 2.2e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 VBB31468.1 - 8.3e-07 29.4 0.1 0.00016 22.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 VBB31468.1 - 4.6e-05 22.9 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 VBB31468.1 - 0.0001 22.8 0.0 0.0063 16.9 0.0 3.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 VBB31468.1 - 0.00016 22.2 0.0 0.00044 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB31468.1 - 0.0031 17.9 0.0 0.17 12.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.17 VBB31468.1 - 0.011 15.4 0.1 0.9 9.2 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.6 VBB31468.1 - 0.026 15.0 0.3 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 VBB31468.1 - 0.054 13.8 0.3 12 6.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 VBB31468.1 - 0.13 12.0 0.0 17 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain CCDC53 PF10152.9 VBB31469.1 - 0.0082 16.6 16.9 0.0096 16.3 16.9 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Peptidase_S49_N PF08496.10 VBB31469.1 - 0.024 14.7 9.1 0.03 14.4 9.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EOS1 PF12326.8 VBB31469.1 - 0.027 14.4 6.4 0.035 14.0 6.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF4746 PF15928.5 VBB31469.1 - 0.07 12.6 10.4 0.085 12.3 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 VBB31469.1 - 0.089 12.8 37.2 0.1 12.6 37.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MID_MedPIWI PF18296.1 VBB31469.1 - 0.092 12.5 17.7 0.1 12.3 17.7 1.0 1 0 0 1 1 1 0 MID domain of medPIWI DDHD PF02862.17 VBB31469.1 - 0.12 12.5 12.5 0.15 12.2 12.5 1.1 1 0 0 1 1 1 0 DDHD domain MMU163 PF17119.5 VBB31469.1 - 0.17 11.0 6.6 0.2 10.8 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis eIF-3_zeta PF05091.12 VBB31469.1 - 0.2 10.6 14.8 0.23 10.4 14.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 VBB31469.1 - 0.24 11.4 14.6 0.27 11.2 14.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF853 PF05872.12 VBB31469.1 - 0.31 9.6 11.1 0.37 9.3 11.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Lin-8 PF03353.15 VBB31469.1 - 0.47 10.0 20.5 0.68 9.4 20.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 VBB31469.1 - 0.59 8.0 14.1 0.68 7.8 14.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PTPRCAP PF15713.5 VBB31469.1 - 0.67 10.2 16.4 0.9 9.8 16.4 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2126 PF09899.9 VBB31469.1 - 0.67 7.9 10.2 0.79 7.7 10.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RP-C_C PF11800.8 VBB31469.1 - 0.78 9.8 13.1 1.2 9.2 13.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2052 PF09747.9 VBB31469.1 - 0.81 9.8 16.5 0.94 9.6 16.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Velvet PF11754.8 VBB31469.1 - 0.82 9.6 15.4 0.97 9.3 15.4 1.1 1 0 0 1 1 1 0 Velvet factor Connexin PF00029.19 VBB31469.1 - 0.92 9.2 8.4 1.2 8.9 8.4 1.3 1 0 0 1 1 1 0 Connexin Endostatin PF06482.11 VBB31469.1 - 1.1 8.7 16.0 1.2 8.6 16.0 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CobT PF06213.12 VBB31469.1 - 1.4 8.3 23.3 1.7 7.9 23.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1387 PF07139.11 VBB31469.1 - 1.4 8.5 17.8 1.7 8.3 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Raftlin PF15250.6 VBB31469.1 - 1.5 7.4 15.1 1.8 7.2 15.1 1.0 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.12 VBB31469.1 - 1.7 8.4 17.2 2 8.1 17.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 VBB31469.1 - 2.1 7.2 13.2 2.6 6.9 13.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Hydin_ADK PF17213.3 VBB31469.1 - 2.1 8.5 13.5 3.3 7.9 13.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GAGA_bind PF06217.12 VBB31469.1 - 2.4 8.4 15.2 2.8 8.2 15.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Suf PF05843.14 VBB31469.1 - 2.5 8.0 23.4 3.4 7.6 23.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CSG2 PF16965.5 VBB31469.1 - 2.8 6.8 7.8 3.4 6.5 7.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 VBB31469.1 - 2.9 6.2 6.2 3.7 5.9 6.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMR1 PF08505.10 VBB31469.1 - 2.9 8.1 21.3 3.8 7.7 21.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 VBB31469.1 - 2.9 6.8 17.3 3.3 6.6 17.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SKA1 PF07160.12 VBB31469.1 - 3.2 7.5 20.5 3.5 7.4 20.5 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PAT1 PF09770.9 VBB31469.1 - 3.7 5.7 27.0 4.2 5.5 27.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 VBB31469.1 - 3.7 6.2 22.1 4.3 6.0 22.1 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 VBB31469.1 - 4.1 5.6 14.6 4.8 5.4 14.6 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 VBB31469.1 - 4.9 7.1 13.5 6.1 6.8 13.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 VBB31469.1 - 6.6 4.7 19.2 7.4 4.6 19.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 VBB31469.1 - 6.8 5.4 13.9 7.1 5.3 13.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Omp28 PF11551.8 VBB31470.1 - 0.06 13.2 0.3 0.17 11.7 0.3 1.7 1 0 0 1 1 1 0 Outer membrane protein Omp28 Longin_2 PF18639.1 VBB31470.1 - 0.23 11.3 5.5 3.3 7.6 0.3 3.4 2 1 1 3 3 3 0 Yeast longin domain TMF_DNA_bd PF12329.8 VBB31470.1 - 0.38 10.8 14.1 2.6 8.1 1.3 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding NUDE_C PF04880.13 VBB31470.1 - 1.4 9.4 9.3 0.17 12.3 2.7 2.6 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region DUF641 PF04859.12 VBB31470.1 - 3.2 8.1 10.2 2.8 8.3 1.5 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TCR PF03638.15 VBB31471.1 - 1.4e-22 79.7 57.6 2.4e-11 43.7 20.8 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 VBB31471.1 - 0.00037 20.6 44.7 0.049 13.8 14.4 2.7 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 Patched PF02460.18 VBB31472.1 - 7.8e-15 54.0 0.0 8.7e-15 53.9 0.0 1.0 1 0 0 1 1 1 1 Patched family FhuF PF06276.12 VBB31473.1 - 0.048 14.1 0.0 0.053 13.9 0.0 1.0 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter DNA_topoisoIV PF00521.20 VBB31474.1 - 2.6e-127 425.3 0.1 8e-127 423.7 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 VBB31474.1 - 6.7e-49 165.4 7.3 3.5e-48 163.1 7.3 2.4 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 VBB31474.1 - 5.4e-27 94.4 1.7 1.5e-26 92.9 1.7 1.9 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 VBB31474.1 - 4.5e-13 49.7 0.0 1.4e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 VBB31474.1 - 4.9e-07 29.9 0.0 1.9e-06 28.0 0.0 2.1 1 0 0 1 1 1 1 Toprim domain ENT PF03735.14 VBB31474.1 - 0.026 14.6 0.3 0.24 11.5 0.4 2.5 2 0 0 2 2 2 0 ENT domain Pkinase PF00069.25 VBB31475.1 - 2.1e-61 207.6 0.0 3.1e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 VBB31475.1 - 2.9e-54 184.6 0.0 4.1e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 VBB31475.1 - 2.1e-44 151.7 0.0 3.3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31475.1 - 8.3e-06 24.8 0.0 9.3e-05 21.4 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 VBB31475.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 VBB31475.1 - 0.024 14.3 0.4 0.6 9.7 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GET2 PF08690.10 VBB31475.1 - 0.11 12.1 0.7 0.28 10.8 0.7 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 Haspin_kinase PF12330.8 VBB31475.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Dscam_C PF12355.8 VBB31475.1 - 1.9 9.5 6.3 0.24 12.4 0.5 2.5 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Collagen PF01391.18 VBB31476.1 - 2.5e-10 40.0 38.4 5.1e-09 35.8 38.4 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_38C PF07748.13 VBB31477.1 - 2.6e-08 34.2 0.0 4.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Ion_trans PF00520.31 VBB31478.1 - 1.7e-29 102.8 2.1 2.5e-29 102.2 2.1 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 VBB31478.1 - 1.2e-08 34.0 2.9 2.8e-06 26.3 0.4 2.2 2 0 0 2 2 2 2 Polycystin cation channel DUF4812 PF16071.5 VBB31478.1 - 0.013 15.3 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) Gpr1_Fun34_YaaH PF01184.19 VBB31478.1 - 0.017 14.7 0.4 0.036 13.7 0.4 1.4 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family AGOG PF09171.10 VBB31478.1 - 0.093 12.0 0.1 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 N-glycosylase/DNA lyase DUF1974 PF09317.11 VBB31478.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) zf-AN1 PF01428.16 VBB31479.1 - 1.9e-21 75.9 33.2 2.1e-12 47.0 9.7 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 VBB31479.1 - 0.0012 19.2 22.3 0.17 12.3 7.8 2.5 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain SRCR_2 PF15494.6 VBB31479.1 - 0.016 15.7 2.2 0.035 14.6 0.3 2.4 2 1 1 3 3 3 0 Scavenger receptor cysteine-rich domain MADF_DNA_bdg PF10545.9 VBB31480.1 - 2e-15 56.8 2.9 2e-15 56.8 2.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 VBB31480.1 - 5.4e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 BESS motif FANCI_HD1 PF14679.6 VBB31480.1 - 0.074 13.0 0.4 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 FANCI helical domain 1 Dus PF01207.17 VBB31481.1 - 3.8e-48 164.2 0.0 5.6e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 VBB31481.1 - 0.0065 16.3 5.2 0.054 13.4 2.6 2.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Neur_chan_LBD PF02931.23 VBB31482.1 - 1e-10 41.4 0.7 1.5e-10 40.9 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 VBB31482.1 - 0.75 8.0 10.4 0.95 7.7 10.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ArabFuran-catal PF09206.11 VBB31483.1 - 0.047 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic Pyridoxal_deC PF00282.19 VBB31484.1 - 6.7e-23 81.0 0.0 7.6e-22 77.5 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 VBB31484.1 - 2.5e-13 49.7 0.0 1.9e-12 46.9 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 VBB31484.1 - 5e-07 29.2 0.1 1.1e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 VBB31484.1 - 0.00013 21.4 0.0 0.00025 20.4 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 VBB31484.1 - 0.0004 19.2 0.0 0.00082 18.2 0.0 1.5 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 VBB31484.1 - 0.0036 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 VBB31484.1 - 0.046 12.2 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Lectin_C PF00059.21 VBB31485.1 - 1.1e-08 35.8 0.9 1.1e-08 35.8 0.9 3.0 3 0 0 3 3 3 1 Lectin C-type domain Mob_synth_C PF06463.13 VBB31485.1 - 0.00058 19.8 2.3 0.14 12.0 0.3 3.1 2 1 0 2 2 2 2 Molybdenum Cofactor Synthesis C DHR-2 PF06920.13 VBB31486.1 - 2.2e-57 194.9 6.5 2.2e-57 194.9 6.5 2.7 2 1 0 2 2 2 1 Dock homology region 2 BTB_2 PF02214.22 VBB31487.1 - 1.6e-19 70.0 0.1 3e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain ThiF PF00899.21 VBB31488.1 - 6.3e-24 84.7 0.0 1.2e-23 83.8 0.0 1.4 1 1 0 1 1 1 1 ThiF family DUF2024 PF09630.10 VBB31488.1 - 0.071 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Ion_trans_2 PF07885.16 VBB31489.1 - 7.1e-29 99.6 13.5 1.3e-15 57.1 4.9 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 VBB31489.1 - 0.035 13.3 6.8 0.032 13.5 3.7 2.0 1 1 1 2 2 2 0 Ion transport protein PAN_1 PF00024.26 VBB31490.1 - 2.1e-10 40.4 9.5 2.1e-05 24.4 0.7 2.1 2 0 0 2 2 2 2 PAN domain Hydrolase_4 PF12146.8 VBB31491.1 - 9e-15 54.6 0.1 2.9e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 VBB31491.1 - 9.3e-13 48.4 0.5 3.8e-06 26.7 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 VBB31491.1 - 1.2e-08 35.9 0.9 3.9e-05 24.4 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 VBB31491.1 - 4.8e-05 22.9 0.0 0.0026 17.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 VBB31491.1 - 0.00038 19.5 0.4 0.002 17.2 0.1 1.9 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 VBB31491.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 VBB31491.1 - 0.02 14.7 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 VBB31491.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 VBB31491.1 - 0.11 12.4 0.1 11 5.8 0.1 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 VBB31491.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MAM PF00629.23 VBB31492.1 - 4.4e-13 49.5 0.1 1.7e-08 34.6 0.0 3.0 2 1 1 3 3 3 2 MAM domain, meprin/A5/mu Piwi PF02171.17 VBB31493.1 - 1.3e-36 126.4 0.2 1.5e-36 126.2 0.2 1.0 1 0 0 1 1 1 1 Piwi domain Glyco_transf_7N PF13733.6 VBB31494.1 - 1.3e-56 190.0 0.0 2.2e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 VBB31494.1 - 4.4e-29 99.9 0.2 9.2e-29 98.9 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Anp1 PF03452.14 VBB31494.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Anp1 Autophagy_N PF03986.13 VBB31496.1 - 3.8e-47 159.7 0.3 7.1e-47 158.8 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 VBB31496.1 - 1.2e-19 70.6 0.7 8e-19 68.0 0.2 2.4 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 VBB31496.1 - 2e-15 56.0 0.6 4.9e-15 54.7 0.6 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF2650 PF10853.8 VBB31499.1 - 1.2e-07 31.4 5.8 1.2e-07 31.4 5.8 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2650) Molybdopterin PF00384.22 VBB31500.1 - 6.3e-55 186.9 0.0 3.3e-53 181.2 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 VBB31500.1 - 7.8e-18 64.3 0.0 1.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 VBB31500.1 - 1.6e-15 56.3 0.1 1.6e-15 56.3 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 VBB31500.1 - 2e-09 37.2 1.3 2.5e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 VBB31500.1 - 6.5e-05 22.7 0.4 0.0078 15.9 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 VBB31500.1 - 0.23 11.3 1.9 7.2 6.6 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain zf-RING_2 PF13639.6 VBB31501.1 - 4.6e-06 26.8 4.1 4.6e-06 26.8 4.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 VBB31501.1 - 0.00014 21.5 1.2 0.00014 21.5 1.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 VBB31501.1 - 0.00025 20.6 3.3 0.00025 20.6 3.3 2.5 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 VBB31501.1 - 0.0015 18.8 3.4 0.0015 18.8 3.4 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 VBB31501.1 - 0.0033 17.4 3.0 0.0033 17.4 3.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB31501.1 - 0.0066 16.5 2.6 0.0066 16.5 2.6 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB31501.1 - 0.013 15.4 3.4 0.013 15.4 3.4 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB31501.1 - 0.018 14.9 0.7 0.018 14.9 0.7 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB31501.1 - 0.033 14.2 5.2 0.076 13.1 5.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-B_box PF00643.24 VBB31501.1 - 1.1 9.5 19.7 1 9.6 11.3 3.0 3 0 0 3 3 3 0 B-box zinc finger LIM PF00412.22 VBB31502.1 - 1e-23 83.3 20.5 4.5e-13 49.2 2.9 3.5 3 1 0 3 3 3 3 LIM domain Zn-ribbon_8 PF09723.10 VBB31502.1 - 0.1 12.7 0.8 0.1 12.7 0.8 4.6 4 1 1 5 5 5 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 VBB31502.1 - 0.5 9.9 10.0 5.4 6.6 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain LMWPc PF01451.21 VBB31503.1 - 4.8e-35 121.0 0.0 7.8e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PTH2 PF01981.16 VBB31503.1 - 4.1e-20 72.2 0.2 9.2e-20 71.1 0.1 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 Latarcin PF10279.9 VBB31503.1 - 0.026 14.9 0.1 0.23 11.9 0.1 2.5 1 1 0 1 1 1 0 Latarcin precursor PfkB PF00294.24 VBB31503.1 - 0.12 11.6 0.1 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Globin PF00042.22 VBB31505.1 - 0.002 18.7 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 Globin Zona_pellucida PF00100.23 VBB31506.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain DHC_N1 PF08385.12 VBB31507.1 - 2.8e-32 112.1 20.9 5.1e-31 107.9 17.4 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 YfkB PF08756.10 VBB31507.1 - 0.00092 19.0 0.2 0.0028 17.5 0.2 1.8 1 0 0 1 1 1 1 YfkB-like domain FliT PF05400.13 VBB31507.1 - 8.2 7.3 7.3 29 5.6 0.1 4.1 4 0 0 4 4 4 0 Flagellar protein FliT SEFIR PF08357.11 VBB31508.1 - 2.9e-16 60.1 0.4 5.2e-16 59.3 0.4 1.4 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 VBB31508.1 - 2.7e-05 24.7 0.1 0.00099 19.7 0.0 2.4 2 0 0 2 2 2 1 TIR domain Claudin_3 PF06653.11 VBB31508.1 - 0.11 12.5 1.3 0.2 11.6 1.3 1.4 1 0 0 1 1 1 0 Tight junction protein, Claudin-like NAPRTase PF04095.16 VBB31509.1 - 1.7e-60 204.7 0.0 2.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RF-1 PF00472.20 VBB31510.1 - 8.8e-15 54.7 4.6 9.6e-15 54.5 3.5 1.6 1 1 0 1 1 1 1 RF-1 domain Zona_pellucida PF00100.23 VBB31512.1 - 8.6e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Tom37 PF10568.9 VBB31513.1 - 4e-28 98.2 0.0 7.7e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 VBB31513.1 - 1.6e-22 79.0 0.1 4.1e-22 77.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 VBB31513.1 - 3.5e-21 75.8 0.0 6.8e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 VBB31513.1 - 0.0003 20.7 0.0 0.00058 19.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2281 PF10047.9 VBB31513.1 - 0.035 14.8 0.0 5 7.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2281) GST_N_3 PF13417.6 VBB31513.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DEAD PF00270.29 VBB31514.1 - 8e-31 107.2 0.0 1.5e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31514.1 - 1.8e-25 89.4 0.7 1.6e-24 86.4 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB31514.1 - 1.9e-08 34.5 0.0 4.5e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 VBB31514.1 - 0.057 13.7 1.7 1.1 9.5 1.7 2.5 1 1 0 1 1 1 0 AAA domain Nup54 PF13874.6 VBB31515.1 - 2.7e-35 121.5 5.1 5.3e-35 120.6 5.1 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 MnmE_helical PF12631.7 VBB31515.1 - 0.00098 19.3 0.9 0.0019 18.4 0.1 1.9 1 1 1 2 2 2 1 MnmE helical domain Nucleoporin_FG PF13634.6 VBB31515.1 - 0.004 18.0 26.0 0.012 16.4 25.9 1.9 1 1 0 1 1 1 1 Nucleoporin FG repeat region HWE_HK PF07536.14 VBB31515.1 - 0.0045 17.7 0.9 0.013 16.2 0.9 1.9 1 0 0 1 1 1 1 HWE histidine kinase Nup54_C PF18437.1 VBB31515.1 - 0.039 13.9 0.2 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain Exonuc_VII_L PF02601.15 VBB31515.1 - 0.15 11.6 6.0 0.24 11.0 6.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Collagen PF01391.18 VBB31516.1 - 1.3e-25 88.9 112.5 0.00019 21.1 12.5 4.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB31516.1 - 5.7e-14 51.9 1.1 8.2e-14 51.4 1.1 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF4231 PF14015.6 VBB31518.1 - 0.28 11.7 0.2 0.28 11.7 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF4418 PF14387.6 VBB31518.1 - 1.4 9.1 8.3 4.6 7.5 2.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) Pkinase PF00069.25 VBB31519.1 - 4.3e-21 75.5 0.0 7.6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31519.1 - 9.4e-13 48.0 0.0 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31519.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Thioredoxin_7 PF13899.6 VBB31520.1 - 4.3e-19 68.5 0.1 8.9e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 VBB31520.1 - 1e-12 47.6 0.1 3.1e-12 46.1 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 VBB31520.1 - 8.3e-06 25.9 0.1 1.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 VBB31520.1 - 0.022 15.2 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain CDC24 PF06395.11 VBB31521.1 - 0.09 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 CDC24 Calponin Cnd2 PF05786.14 VBB31522.1 - 1.2e-08 34.2 32.5 5.9e-08 31.9 11.8 3.5 3 1 0 3 3 3 2 Condensin complex subunit 2 Exo70 PF03081.15 VBB31522.1 - 0.0059 15.7 0.1 0.035 13.2 0.0 2.1 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Cnd2 PF05786.14 VBB31523.1 - 4.8e-06 25.6 0.1 5.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 HSR PF03172.13 VBB31523.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 HSR domain Oberon_cc PF16312.5 VBB31524.1 - 0.0011 19.0 0.6 0.0017 18.3 0.6 1.4 1 1 0 1 1 1 1 Coiled-coil region of Oberon HV_small_capsid PF17086.5 VBB31524.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Small capsid protein of Herpesviridae NNMT_PNMT_TEMT PF01234.17 VBB31525.1 - 4.8e-60 202.9 1.2 9.9e-33 113.4 0.0 2.0 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 VBB31525.1 - 0.00089 19.1 0.0 0.011 15.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain NodS PF05401.11 VBB31525.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Actin PF00022.19 VBB31526.1 - 3.7e-67 226.7 0.0 4.3e-66 223.2 0.0 1.9 1 1 0 1 1 1 1 Actin MOR2-PAG1_N PF14222.6 VBB31527.1 - 3.9e-135 451.9 4.1 5.1e-135 451.5 4.1 1.1 1 0 0 1 1 1 1 Cell morphogenesis N-terminal AI-2E_transport PF01594.16 VBB31527.1 - 0.024 13.8 1.8 6.9 5.7 0.1 3.3 3 0 0 3 3 3 0 AI-2E family transporter TAF6_C PF07571.13 VBB31527.1 - 0.18 12.2 0.3 36 4.8 0.2 3.5 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain DCB PF16213.5 VBB31527.1 - 0.68 9.6 3.3 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 MADF_DNA_bdg PF10545.9 VBB31528.1 - 1.9e-16 60.1 0.4 4.9e-16 58.8 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB31528.1 - 8.2e-10 38.9 1.7 9.1e-10 38.8 0.5 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Ribosomal_S28e PF01200.18 VBB31529.1 - 0.067 13.2 0.0 2.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S28e LRR_8 PF13855.6 VBB31530.1 - 8.2e-85 278.5 55.7 2.7e-15 55.9 0.6 7.6 2 2 8 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 VBB31530.1 - 2.4e-30 104.0 35.1 3.9e-06 27.1 0.2 7.9 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB31530.1 - 8.5e-20 71.0 1.7 8.6e-07 29.0 0.1 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB31530.1 - 9e-13 48.1 18.1 0.00037 20.0 1.4 5.3 1 1 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 VBB31530.1 - 1.5e-10 40.1 25.1 0.55 11.0 0.1 11.3 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.6 VBB31530.1 - 5.2e-05 23.0 38.8 0.43 10.8 0.1 9.5 11 0 0 11 11 11 4 Leucine Rich repeat LRR_8 PF13855.6 VBB31531.1 - 6.7e-72 237.2 75.6 4.7e-16 58.3 3.2 7.7 1 1 8 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 VBB31531.1 - 9.6e-28 95.8 48.8 6.9e-06 26.3 0.4 8.4 4 2 6 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB31531.1 - 4.6e-26 91.3 7.2 4.5e-11 42.8 0.3 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB31531.1 - 2.1e-12 46.9 24.0 0.00014 21.5 0.8 5.7 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 VBB31531.1 - 3.2e-12 45.2 36.0 1 10.2 0.0 12.8 11 1 0 11 11 11 4 Leucine Rich Repeat CHDNT PF08073.12 VBB31531.1 - 0.18 11.8 0.0 0.49 10.4 0.0 1.7 1 0 0 1 1 1 0 CHDNT (NUC034) domain LRR_8 PF13855.6 VBB31532.1 - 3.7e-54 180.3 89.9 6.7e-12 45.0 6.4 6.3 2 1 7 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 VBB31532.1 - 1.6e-25 88.7 39.4 2.9e-07 30.7 0.9 6.1 6 0 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB31532.1 - 1.1e-14 54.5 24.0 2.8e-07 30.5 3.0 3.5 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB31532.1 - 3.9e-12 46.0 25.4 2.6e-06 27.1 5.6 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 VBB31532.1 - 0.0022 18.3 24.2 4.1 8.3 1.0 9.5 10 0 0 10 10 10 1 Leucine Rich Repeat TFIIA PF03153.13 VBB31534.1 - 9e-64 217.0 5.8 1.3e-63 216.5 5.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.21 VBB31535.1 - 6e-57 193.0 1.2 1e-56 192.2 0.1 1.9 2 0 0 2 2 2 1 Adaptor complexes medium subunit family PH PF00169.29 VBB31535.1 - 0.0031 18.0 0.1 0.013 16.0 0.1 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 VBB31535.1 - 0.018 15.4 0.0 0.11 12.9 0.0 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain C2 PF00168.30 VBB31537.1 - 4.1e-18 65.6 0.0 8.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain PDZ PF00595.24 VBB31537.1 - 8e-08 32.5 0.3 1.7e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB31537.1 - 6.1e-06 26.0 0.1 1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain S-methyl_trans PF02574.16 VBB31537.1 - 8.9e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Adenosine_kin PF04008.14 VBB31537.1 - 0.12 12.2 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Adenosine specific kinase DUF4788 PF16032.5 VBB31538.1 - 0.054 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) IBR PF01485.21 VBB31539.1 - 3.6e-13 49.5 7.9 3.6e-13 49.5 7.9 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain eIF-5_eIF-2B PF01873.17 VBB31540.1 - 3.7e-41 139.7 0.5 3.7e-41 139.7 0.5 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 DTW PF03942.15 VBB31540.1 - 6.2e-25 88.1 0.0 1.1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 DTW domain DZR PF12773.7 VBB31540.1 - 0.19 11.8 7.4 0.82 9.7 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 VBB31540.1 - 7.1 6.7 8.1 16 5.6 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_2 PF03107.16 VBB31540.1 - 9 6.7 10.3 1.4 9.3 1.4 2.5 2 0 0 2 2 2 0 C1 domain Spt20 PF12090.8 VBB31542.1 - 3.4 7.2 14.4 0.23 11.1 7.7 1.9 2 0 0 2 2 2 0 Spt20 family Ccdc124 PF06244.12 VBB31544.1 - 1.6e-24 86.9 10.2 1.6e-24 86.9 10.2 2.5 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 ubiquitin PF00240.23 VBB31544.1 - 0.00023 20.8 0.0 0.00058 19.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 VBB31544.1 - 0.036 14.0 0.2 0.081 12.9 0.2 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_S46 PF10459.9 VBB31544.1 - 3.7 6.1 19.1 5 5.6 19.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Syja_N PF02383.18 VBB31545.1 - 2.4e-72 244.0 0.0 5.5e-72 242.8 0.0 1.6 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 VBB31545.1 - 5.3e-13 48.7 0.2 4.5e-12 45.7 0.0 2.5 2 1 1 3 3 3 1 Inositol phosphatase Mito_carr PF00153.27 VBB31546.1 - 1.5e-69 229.9 0.5 4.2e-24 84.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 VBB31546.1 - 5e-16 58.9 0.5 1.7e-07 31.6 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB31546.1 - 1.8e-10 39.9 0.4 0.0034 17.2 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 VBB31546.1 - 2.5e-09 36.0 3.8 0.0007 19.0 0.1 5.0 4 0 0 4 4 4 2 EF hand RRM_1 PF00076.22 VBB31546.1 - 2.4e-07 30.5 0.2 7.3e-07 28.9 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.6 VBB31546.1 - 2.1e-05 24.2 0.8 2.4 8.1 0.0 4.4 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB31546.1 - 0.0001 21.6 0.4 0.2 11.2 0.0 3.2 2 0 0 2 2 2 2 EF hand RRM_5 PF13893.6 VBB31546.1 - 0.0037 16.8 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_9 PF14658.6 VBB31546.1 - 0.015 15.6 0.0 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Limkain-b1 PF11608.8 VBB31546.1 - 0.024 14.7 0.1 0.11 12.5 0.1 2.1 1 0 0 1 1 1 0 Limkain b1 DUF2624 PF11116.8 VBB31546.1 - 0.062 14.2 0.1 0.69 10.8 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) Med22 PF06179.12 VBB31547.1 - 2.9e-20 72.4 0.6 4e-20 72.0 0.6 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SNAP PF14938.6 VBB31548.1 - 3.8e-07 29.8 1.4 8.7e-07 28.6 1.3 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 VBB31548.1 - 0.007 16.9 4.0 0.62 10.6 0.6 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat AChE_tetra PF08674.10 VBB31548.1 - 0.49 10.1 3.2 1.5 8.5 0.9 2.5 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Ig_3 PF13927.6 VBB31550.1 - 3e-18 66.2 0.0 8e-13 48.8 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 VBB31550.1 - 1e-16 60.7 0.1 1.4e-13 50.7 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB31550.1 - 1.6e-15 57.2 0.0 6.9e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 VBB31550.1 - 3.7e-11 43.0 0.3 8.2e-07 29.1 0.0 3.2 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 VBB31550.1 - 1.4e-09 38.0 0.6 0.0035 17.5 0.0 3.4 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 VBB31550.1 - 0.00059 19.4 0.0 0.27 10.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 VBB31550.1 - 0.0025 18.2 0.0 0.89 10.0 0.0 2.9 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TMEM154 PF15102.6 VBB31550.1 - 0.044 13.7 1.6 0.066 13.1 0.9 1.6 2 0 0 2 2 2 0 TMEM154 protein family T2SSF PF00482.23 VBB31550.1 - 0.23 11.4 2.6 0.49 10.4 2.6 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ODV-E18 PF10717.9 VBB31550.1 - 2.3 8.1 5.2 11 6.0 1.5 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 GYF PF02213.16 VBB31551.1 - 1e-15 57.1 0.4 2e-15 56.1 0.4 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 VBB31551.1 - 0.019 14.7 0.5 0.064 13.1 0.1 2.2 2 0 0 2 2 2 0 GYF domain 2 MRP-S22 PF10245.9 VBB31552.1 - 2.8e-54 184.4 0.0 5e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 ANF_receptor PF01094.28 VBB31553.1 - 1.3e-64 218.5 0.0 1.7e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 VBB31553.1 - 5.7e-38 131.0 8.4 5.7e-38 131.0 8.4 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 VBB31553.1 - 1.3e-09 38.2 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Csm1_N PF18504.1 VBB31553.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain CAP_GLY PF01302.25 VBB31556.1 - 8.5e-22 77.0 1.0 1.3e-21 76.4 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Agarase_CBM PF17992.1 VBB31556.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Agarase CBM like domain Clat_adaptor_s PF01217.20 VBB31557.1 - 1.1e-57 193.9 4.7 1.3e-57 193.7 4.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 VBB31557.1 - 0.0011 17.6 0.6 0.0014 17.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) Pkinase_Tyr PF07714.17 VBB31558.1 - 2.6e-51 174.4 0.0 1.1e-50 172.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB31558.1 - 8.2e-51 172.9 0.0 1.8e-50 171.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 VBB31558.1 - 1.3e-13 50.6 0.1 2.6e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB31558.1 - 1.4e-12 47.0 0.6 2.8e-12 46.0 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB31558.1 - 8.2e-10 38.2 0.2 1.9e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kdo PF06293.14 VBB31558.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB31558.1 - 0.043 12.6 0.0 0.092 11.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase TUG-UBL1 PF11470.8 VBB31559.1 - 1.8e-23 82.6 0.1 2.2e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 VBB31559.1 - 9.7e-07 28.8 0.9 1.3e-06 28.4 0.3 1.6 2 0 0 2 2 2 1 Raf-like Ras-binding domain Rad60-SLD PF11976.8 VBB31559.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cobl PF09469.10 VBB31559.1 - 0.011 16.0 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Y1_Tnp PF01797.16 VBB31559.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Transposase IS200 like APOBEC_N PF08210.11 VBB31560.1 - 8.5e-22 77.9 4.1 8.5e-22 77.9 4.1 2.3 1 1 1 2 2 2 1 APOBEC-like N-terminal domain TCR PF03638.15 VBB31560.1 - 0.0095 16.2 22.4 0.0095 16.2 22.4 5.1 3 1 2 5 5 5 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain I-set PF07679.16 VBB31561.1 - 7.7e-45 150.9 1.2 1.6e-16 60.1 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB31561.1 - 8e-39 132.1 1.3 2.9e-14 53.4 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB31561.1 - 5.5e-28 97.0 2.1 6.6e-11 42.2 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB31561.1 - 3.5e-23 81.7 1.7 6.1e-08 32.9 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 VBB31561.1 - 3.2e-19 69.1 1.4 1.3e-05 25.3 0.2 4.8 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB31561.1 - 6.7e-09 35.7 0.2 0.0088 16.1 0.0 3.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 VBB31561.1 - 2.7e-07 30.0 0.0 0.56 9.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 VBB31561.1 - 0.00014 21.9 0.1 1.8 8.7 0.0 3.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 VBB31561.1 - 0.001 19.3 0.2 3.1 8.1 0.1 4.4 3 2 1 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 VBB31561.1 - 0.0013 18.9 0.0 2.1 8.6 0.0 3.0 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 Adeno_E3_CR1 PF02440.15 VBB31561.1 - 0.0013 18.4 0.7 0.62 9.9 0.2 3.0 2 1 0 2 2 2 2 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 VBB31561.1 - 0.019 15.0 6.9 0.47 10.4 0.0 2.9 2 1 1 3 3 3 0 CD47 immunoglobulin-like domain PI31_Prot_N PF11566.8 VBB31561.1 - 0.044 13.6 0.2 0.095 12.5 0.2 1.5 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal YukC PF10140.9 VBB31561.1 - 0.15 10.9 0.0 0.39 9.5 0.0 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC LRR_6 PF13516.6 VBB31563.1 - 6.6e-05 22.7 15.4 0.53 10.5 0.1 7.7 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.33 VBB31563.1 - 0.00043 20.1 10.7 0.0016 18.3 2.6 3.8 4 0 0 4 4 4 2 F-box domain LRR_4 PF12799.7 VBB31563.1 - 0.0044 17.4 14.7 3.5 8.2 0.0 6.6 4 1 2 6 6 6 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 VBB31563.1 - 0.016 15.1 0.5 0.016 15.1 0.5 3.2 3 0 0 3 3 3 0 F-box-like DUF2853 PF11015.8 VBB31563.1 - 0.063 14.0 0.1 0.18 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) CH PF00307.31 VBB31567.1 - 9e-15 54.8 0.5 2.2e-14 53.6 0.2 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.11 VBB31567.1 - 0.00019 21.6 1.2 0.00023 21.4 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin CAMSAP_CH PF11971.8 VBB31567.1 - 0.095 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain SRP54 PF00448.22 VBB31569.1 - 4.5e-76 254.9 0.0 7e-76 254.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 VBB31569.1 - 1.7e-31 108.7 6.6 3e-31 108.0 2.0 2.9 2 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 VBB31569.1 - 1.2e-18 67.1 1.6 1.2e-18 67.1 1.6 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 VBB31569.1 - 1.6e-05 25.1 0.0 4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 VBB31569.1 - 4.5e-05 23.0 2.0 0.059 12.8 0.4 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.19 VBB31569.1 - 9.8e-05 22.0 0.2 0.0014 18.2 0.3 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 VBB31569.1 - 0.00018 21.5 0.0 0.00063 19.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 VBB31569.1 - 0.0018 18.3 0.3 0.0064 16.5 0.3 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 VBB31569.1 - 0.0021 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 VBB31569.1 - 0.0023 18.4 0.1 0.011 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF2209 PF09974.9 VBB31569.1 - 0.0035 17.7 0.9 0.012 15.9 0.2 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_16 PF13191.6 VBB31569.1 - 0.0036 17.7 0.0 0.0079 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 VBB31569.1 - 0.0099 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase CLP1_P PF16575.5 VBB31569.1 - 0.014 15.2 0.3 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 VBB31569.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 VBB31569.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 VBB31569.1 - 0.022 14.6 0.1 0.075 12.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 VBB31569.1 - 0.024 14.7 0.8 0.14 12.2 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 VBB31569.1 - 0.029 13.4 0.1 1.3 8.0 0.0 3.1 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 VBB31569.1 - 0.04 14.3 1.9 0.55 10.7 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 VBB31569.1 - 0.044 13.5 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.17 VBB31569.1 - 0.052 13.3 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 VBB31569.1 - 0.066 13.5 0.1 0.26 11.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 VBB31569.1 - 0.085 13.2 0.1 0.16 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 VBB31569.1 - 0.15 12.6 0.1 0.42 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF948 PF06103.11 VBB31569.1 - 0.98 9.7 3.6 34 4.8 0.8 3.3 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) DEAD PF00270.29 VBB31570.1 - 5.6e-30 104.4 0.0 9.9e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31570.1 - 1.5e-26 92.9 0.1 5.8e-26 91.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB31570.1 - 0.00038 20.5 0.0 0.00082 19.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 VBB31570.1 - 0.0031 17.8 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 VBB31570.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF851 PF05867.11 VBB31571.1 - 4.7e-12 45.9 2.1 4.7e-12 45.9 2.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF851) BACK PF07707.15 VBB31572.1 - 2e-06 27.8 0.6 5.2e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch CobD_Cbib PF03186.13 VBB31572.1 - 0.074 12.2 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Pkinase PF00069.25 VBB31573.1 - 3.7e-60 203.5 0.0 8.3e-60 202.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31573.1 - 2.4e-36 125.4 0.0 1.3e-35 123.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31573.1 - 5.7e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Coiled-coil_56 PF09813.9 VBB31573.1 - 1.7e-05 24.8 1.1 2.3e-05 24.4 0.2 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 DUF3687 PF12459.8 VBB31573.1 - 0.18 11.4 1.2 0.48 10.0 1.2 1.7 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein 7tm_2 PF00002.24 VBB31574.1 - 3.9e-29 101.6 15.5 5.8e-22 78.2 5.4 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) GAIN PF16489.5 VBB31574.1 - 4.2e-22 78.6 0.5 6.9e-22 77.9 0.5 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain GPS PF01825.21 VBB31574.1 - 1.7e-13 50.9 8.3 1.7e-13 50.9 8.3 1.9 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 VBB31574.1 - 4.2e-07 30.2 0.8 4.2e-07 30.2 0.8 2.2 2 0 0 2 2 2 1 Hormone receptor domain Gal_Lectin PF02140.18 VBB31574.1 - 2e-05 24.9 0.2 8.1e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Galactose binding lectin domain Mito_fiss_reg PF05308.11 VBB31574.1 - 9.3 6.3 9.8 17 5.4 9.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Zn_ribbon_recom PF13408.6 VBB31575.1 - 0.33 11.5 6.3 0.84 10.2 6.3 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LicD PF04991.13 VBB31576.1 - 5.5e-05 23.4 0.3 0.0001 22.5 0.3 1.4 1 0 0 1 1 1 1 LicD family DUF4636 PF15468.6 VBB31577.1 - 0.00036 20.3 2.4 0.00069 19.4 2.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4636) RRM_1 PF00076.22 VBB31577.1 - 0.0026 17.5 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orf78 PF06024.12 VBB31577.1 - 1.3 9.3 0.0 1.3 9.3 0.0 2.7 1 1 2 3 3 3 0 Orf78 (ac78) UPF0239 PF06783.11 VBB31577.1 - 3.6 7.8 0.0 3.6 7.8 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0239) BIRC6 PF12356.8 VBB31577.1 - 5.5 6.4 5.5 0.87 9.0 0.2 2.1 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 RRM_1 PF00076.22 VBB31578.1 - 9.5e-16 57.4 0.0 1.1e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 VBB31578.1 - 0.0016 18.4 0.2 0.012 15.6 0.1 2.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 VBB31578.1 - 0.0038 16.8 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOBP PF15279.6 VBB31578.1 - 0.13 12.9 8.9 0.18 12.4 8.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.9 VBB31578.1 - 0.16 10.8 16.3 0.2 10.5 16.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 VBB31578.1 - 3.6 6.2 14.7 4.8 5.8 14.7 1.1 1 0 0 1 1 1 0 Presenilin FancD2 PF14631.6 VBB31578.1 - 4.7 4.5 7.2 0.51 7.7 2.8 1.5 1 1 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Neur_chan_memb PF02932.16 VBB31578.1 - 6.9 6.7 7.5 11 6.0 7.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 VBB31578.1 - 8.8 5.0 15.2 12 4.6 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LSM PF01423.22 VBB31579.1 - 6.9e-19 67.3 0.9 8.6e-19 67.0 0.9 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 VBB31579.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Y_phosphatase PF00102.27 VBB31580.1 - 1.3e-101 339.1 0.0 1.3e-84 283.5 0.0 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 VBB31580.1 - 3e-15 56.3 0.3 1.1e-09 38.4 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain PTPlike_phytase PF14566.6 VBB31580.1 - 0.0024 18.0 0.0 0.0075 16.4 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 VBB31580.1 - 0.039 13.9 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF4381 PF14316.6 VBB31580.1 - 3 8.1 5.2 0.53 10.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) U1snRNP70_N PF12220.8 VBB31581.1 - 1.9e-23 82.9 5.3 1.9e-23 82.9 5.3 2.3 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 VBB31581.1 - 6.8e-19 67.5 0.1 1.1e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 VBB31581.1 - 0.032 14.2 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 RL domain RRM_occluded PF16842.5 VBB31581.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif TTR-52 PF01060.23 VBB31582.1 - 8.2e-28 96.9 0.0 1.1e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family CarboxypepD_reg PF13620.6 VBB31582.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain TTR-52 PF01060.23 VBB31583.1 - 1.7e-25 89.5 0.0 2.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 VBB31584.1 - 1.2e-26 93.2 0.0 1.6e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family CarboxypepD_reg PF13620.6 VBB31584.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain bMG3 PF11974.8 VBB31584.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Ribosomal_L50 PF10501.9 VBB31584.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S CH PF00307.31 VBB31586.1 - 1.9e-24 85.9 0.1 3.1e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB31586.1 - 0.00093 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Aldedh PF00171.22 VBB31587.1 - 4.1e-162 539.9 0.3 5.1e-162 539.6 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_C92 PF05708.12 VBB31587.1 - 2e-13 50.8 0.1 5e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Lipase_3 PF01764.25 VBB31588.1 - 3.1e-16 59.5 0.0 5.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 VBB31588.1 - 0.22 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PP2C PF00481.21 VBB31589.1 - 2.4e-15 56.9 2.6 5.3e-15 55.7 0.0 2.2 2 1 1 3 3 3 1 Protein phosphatase 2C FAA_hydrolase PF01557.18 VBB31590.1 - 4.1e-57 193.4 0.0 4.6e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sina PF03145.16 VBB31591.1 - 2e-77 259.7 0.7 3.4e-77 258.9 0.7 1.4 1 0 0 1 1 1 1 Seven in absentia protein family RabGAP-TBC PF00566.18 VBB31591.1 - 2e-33 115.9 3.6 7.6e-30 104.2 0.7 2.5 2 1 0 2 2 2 2 Rab-GTPase-TBC domain CENP-T_C PF15511.6 VBB31592.1 - 1.2e-08 35.0 0.1 1.5e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 VBB31592.1 - 1.7e-05 25.1 0.1 2.3e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 VBB31592.1 - 4.3e-05 23.7 0.1 6.6e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 VBB31592.1 - 4.4e-05 23.6 0.1 6e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 VBB31592.1 - 6.4e-05 23.3 0.2 7.4e-05 23.1 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 VBB31592.1 - 0.0049 16.8 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 VBB31592.1 - 0.0074 16.4 0.0 0.0086 16.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 VBB31593.1 - 5.4e-51 173.5 0.0 6.7e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31593.1 - 4.9e-36 124.3 0.0 6.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31593.1 - 4.5e-05 22.9 0.0 0.00022 20.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 VBB31593.1 - 0.0041 16.2 0.1 0.008 15.3 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 VBB31593.1 - 0.045 12.7 0.3 0.071 12.0 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB31593.1 - 0.053 12.3 0.0 0.092 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 VBB31593.1 - 0.076 12.6 0.2 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1922 PF09082.10 VBB31593.1 - 0.089 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) zf-MYND PF01753.18 VBB31594.1 - 6e-05 23.1 13.5 6e-05 23.1 13.5 4.1 3 1 0 3 3 3 1 MYND finger TPR_12 PF13424.6 VBB31594.1 - 0.0045 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB31594.1 - 0.17 11.8 0.0 0.59 10.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat FYDLN_acid PF09538.10 VBB31594.1 - 2.2 9.0 4.7 4.7 7.9 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) WXG100 PF06013.12 VBB31595.1 - 0.073 13.3 3.1 14 6.0 0.2 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ArgoMid PF16487.5 VBB31595.1 - 0.19 12.0 2.6 10 6.5 0.0 3.3 2 1 1 3 3 3 0 Mid domain of argonaute Apolipoprotein PF01442.18 VBB31595.1 - 0.42 10.5 6.7 13 5.6 4.2 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2205 PF10224.9 VBB31595.1 - 1.8 8.6 10.4 0.4 10.7 0.8 3.8 2 1 1 3 3 3 0 Short coiled-coil protein COG2 PF06148.11 VBB31595.1 - 3.9 7.6 11.7 13 5.9 2.0 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Complex1_LYR_2 PF13233.6 VBB31595.1 - 4.9 8.0 7.6 3.6 8.4 1.0 3.0 1 1 2 3 3 3 0 Complex1_LYR-like UPF0640 PF15114.6 VBB31596.1 - 9.8e-07 28.5 0.6 1.3e-06 28.1 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 COX14 PF14880.6 VBB31597.1 - 2.7e-11 43.1 0.1 3.6e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Phtf-FEM1B_bdg PF12129.8 VBB31597.1 - 0.045 13.6 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor DUF3042 PF11240.8 VBB31597.1 - 0.075 13.1 0.3 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) dsrm PF00035.26 VBB31598.1 - 2.5e-19 69.8 0.9 5.6e-11 43.0 0.2 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 VBB31598.1 - 9.5e-05 22.5 0.5 0.53 10.5 0.0 3.5 3 1 0 3 3 3 2 Dicer dimerisation domain DND1_DSRM PF14709.7 VBB31598.1 - 0.0015 18.8 5.4 0.056 13.7 0.4 4.1 3 2 0 3 3 3 1 double strand RNA binding domain from DEAD END PROTEIN 1 FAA_hydro_N_2 PF18288.1 VBB31598.1 - 0.016 15.6 0.7 0.036 14.5 0.2 1.8 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 LPP20 PF02169.16 VBB31598.1 - 0.5 10.7 4.4 14 6.1 0.0 3.6 4 0 0 4 4 4 0 LPP20 lipoprotein Polyketide_cyc PF03364.20 VBB31599.1 - 1.4e-19 70.6 0.2 1.7e-19 70.3 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RIG-I_C-RD PF11648.8 VBB31600.1 - 2.7e-19 69.5 4.0 2.7e-19 69.5 4.0 2.2 2 0 0 2 2 2 1 C-terminal domain of RIG-I ResIII PF04851.15 VBB31600.1 - 5e-16 59.2 0.5 7e-15 55.4 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB31600.1 - 1.2e-15 57.7 0.0 1.8e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31600.1 - 6.5e-11 42.6 0.7 2.9e-10 40.5 0.3 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Yippee-Mis18 PF03226.14 VBB31600.1 - 0.0028 17.8 2.9 0.0072 16.5 2.9 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA PF00004.29 VBB31600.1 - 0.0029 18.0 0.0 0.02 15.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 VBB31600.1 - 0.012 15.9 3.1 0.058 13.7 0.1 3.7 5 1 0 5 5 5 0 AAA domain AAA_7 PF12775.7 VBB31600.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 VBB31600.1 - 0.029 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 VBB31600.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 VBB31600.1 - 0.054 13.0 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 VBB31600.1 - 0.064 13.0 1.4 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 VBB31600.1 - 0.079 12.7 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 VBB31600.1 - 0.18 11.3 0.0 0.67 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain eIF-5_eIF-2B PF01873.17 VBB31602.1 - 1.4e-36 124.9 0.3 3.4e-36 123.7 0.3 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 VBB31602.1 - 8.2e-21 73.9 0.4 2.2e-20 72.5 0.4 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon SLC12 PF03522.15 VBB31603.1 - 0.025 13.6 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 p450 PF00067.22 VBB31605.1 - 9.2e-89 298.3 0.0 1.2e-88 297.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3382 PF11862.8 VBB31605.1 - 0.041 14.2 0.1 0.084 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) MOLO1 PF17175.4 VBB31605.1 - 0.14 12.3 0.7 0.78 9.9 0.1 2.6 2 1 0 2 2 2 0 Modulator of levamisole receptor-1 Forkhead PF00250.18 VBB31606.1 - 1.9e-28 98.5 0.1 6.8e-28 96.8 0.1 2.0 1 0 0 1 1 1 1 Forkhead domain FOXP-CC PF16159.5 VBB31606.1 - 1.3e-23 83.4 7.4 1.3e-23 83.4 7.4 2.7 3 0 0 3 3 3 1 FOXP coiled-coil domain SUIM_assoc PF16619.5 VBB31606.1 - 0.038 14.1 7.9 0.16 12.0 7.9 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 VBB31607.1 - 1e-29 102.1 0.0 4.1e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB31607.1 - 1.9e-08 34.2 0.1 0.0029 17.6 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 VBB31607.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 VBB31607.1 - 0.027 14.6 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif TPR_1 PF00515.28 VBB31608.1 - 1.6e-22 78.3 27.4 0.0046 16.7 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 VBB31608.1 - 6.2e-22 75.9 24.7 0.005 16.9 0.0 10.1 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 VBB31608.1 - 2.8e-21 73.9 20.5 0.0019 18.3 0.1 9.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 VBB31608.1 - 3.5e-17 62.5 17.7 0.0017 18.6 0.1 7.3 5 3 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 VBB31608.1 - 3.6e-13 49.0 12.0 0.0038 16.9 0.0 7.6 6 1 2 8 8 8 3 TPR repeat TPR_17 PF13431.6 VBB31608.1 - 3.2e-10 39.7 18.6 0.031 14.6 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB31608.1 - 2.3e-07 31.4 10.5 0.15 12.7 0.1 5.5 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 VBB31608.1 - 5.6e-07 30.0 19.5 0.016 15.7 0.0 6.0 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB31608.1 - 9.5e-07 29.1 10.1 2.6 9.1 0.0 7.1 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB31608.1 - 1.4e-05 25.1 7.4 0.22 11.7 0.2 5.4 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB31608.1 - 0.00024 20.9 10.0 4.5 7.5 0.1 7.9 8 1 1 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB31608.1 - 0.00092 19.4 20.1 0.14 12.4 4.9 5.5 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB31608.1 - 0.0056 17.2 7.2 6.9 7.5 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 VBB31608.1 - 0.017 13.9 0.4 0.71 8.5 0.0 2.4 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat BEX PF04538.12 VBB31608.1 - 0.067 13.8 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Brain expressed X-linked like family AviRa PF11599.8 VBB31608.1 - 0.081 12.4 1.6 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Asn_synthase PF00733.21 VBB31609.1 - 1.1e-15 58.1 0.0 1e-06 28.7 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 VBB31609.1 - 8.3e-06 25.7 0.1 4.2e-05 23.5 0.0 2.1 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 VBB31609.1 - 0.14 12.4 0.0 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain 2OG-FeII_Oxy_3 PF13640.6 VBB31610.1 - 1.7e-18 67.3 0.3 6.4e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 VBB31610.1 - 4e-10 39.6 5.0 4e-10 39.6 5.0 2.4 2 0 0 2 2 2 1 MYND finger 2OG-FeII_Oxy_4 PF13661.6 VBB31610.1 - 1.1e-09 38.8 0.0 4.3e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4145 PF13643.6 VBB31610.1 - 0.084 13.0 0.6 3.5 7.8 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4145) zf-Mss51 PF13824.6 VBB31610.1 - 0.1 12.7 10.8 0.068 13.3 6.6 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Synaptonemal_3 PF15191.6 VBB31610.1 - 0.11 12.3 0.0 0.44 10.4 0.0 2.0 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 DUF1758 PF05585.12 VBB31611.1 - 3.3e-09 36.7 0.3 4.1e-09 36.4 0.3 1.1 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 VBB31611.1 - 1.6e-05 25.5 0.0 2.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 VBB31611.1 - 7.4e-05 23.2 0.1 9.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 VBB31611.1 - 0.0099 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 VBB31611.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DUF2457 PF10446.9 VBB31612.1 - 0.012 14.8 22.0 0.014 14.6 22.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 VBB31612.1 - 0.016 14.6 14.0 0.017 14.5 14.0 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 VBB31612.1 - 0.019 13.3 5.8 0.02 13.2 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 VBB31612.1 - 0.04 13.3 6.8 0.039 13.4 6.8 1.0 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 VBB31612.1 - 0.23 11.2 16.7 0.27 10.9 16.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 VBB31612.1 - 0.36 9.8 7.6 0.38 9.8 7.6 1.1 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 VBB31612.1 - 0.37 9.3 10.2 0.36 9.3 10.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Utp14 PF04615.13 VBB31612.1 - 0.52 8.8 9.8 0.6 8.6 9.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2722 PF10846.8 VBB31612.1 - 0.78 8.6 8.3 0.8 8.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Rhabdo_ncap PF00945.18 VBB31612.1 - 1.5 7.6 7.5 1.7 7.4 7.5 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Sporozoite_P67 PF05642.11 VBB31612.1 - 1.6 6.7 5.7 1.7 6.6 5.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 VBB31612.1 - 2 6.5 13.3 2.3 6.3 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 VBB31612.1 - 2.3 8.0 11.9 2.9 7.7 11.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SGT1 PF07093.11 VBB31612.1 - 2.8 6.3 7.3 3.1 6.1 7.3 1.0 1 0 0 1 1 1 0 SGT1 protein BTV_NS2 PF04514.12 VBB31612.1 - 5.2 5.8 11.1 5.7 5.7 11.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Baculo_11_kDa PF06143.11 VBB31613.1 - 0.00047 19.7 0.1 0.00068 19.2 0.1 1.2 1 0 0 1 1 1 1 Baculovirus 11 kDa family Myosin_tail_1 PF01576.19 VBB31614.1 - 1.3e-53 182.2 96.4 1.7e-53 181.8 96.4 1.0 1 0 0 1 1 1 1 Myosin tail C1_1 PF00130.22 VBB31614.1 - 6.5e-15 54.8 5.2 1.2e-14 53.9 5.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF812 PF05667.11 VBB31614.1 - 0.00028 19.9 32.1 0.00028 19.9 32.1 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF812) C1_2 PF03107.16 VBB31614.1 - 0.0012 19.1 4.5 0.0036 17.6 4.5 1.8 1 0 0 1 1 1 1 C1 domain DUF1664 PF07889.12 VBB31614.1 - 0.0019 18.2 50.1 0.087 12.9 3.6 5.8 1 1 5 6 6 6 3 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 VBB31614.1 - 0.0054 16.8 8.5 0.0054 16.8 8.5 7.7 2 2 6 8 8 7 1 TolA binding protein trimerisation PHD PF00628.29 VBB31614.1 - 0.22 11.5 3.7 0.48 10.4 3.7 1.6 1 0 0 1 1 1 0 PHD-finger ADK_lid PF05191.14 VBB31614.1 - 0.23 11.5 2.8 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zf_RING PF16744.5 VBB31614.1 - 0.46 10.6 4.8 0.22 11.6 0.9 2.6 2 0 0 2 2 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 VBB31614.1 - 0.66 10.3 3.6 1.8 8.9 3.6 1.7 1 0 0 1 1 1 0 RING-like domain Spc7 PF08317.11 VBB31614.1 - 1.9 7.3 88.0 0.027 13.4 23.8 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein Fib_alpha PF08702.10 VBB31614.1 - 3 8.0 64.0 0.035 14.3 8.1 4.9 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Spore_SspJ PF09575.10 VBB31614.1 - 4.6 7.7 9.4 0.98 9.8 2.5 3.5 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) DUF3450 PF11932.8 VBB31614.1 - 4.9 6.4 77.9 0.046 13.0 15.8 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) T3SSipB PF16535.5 VBB31614.1 - 7.3 7.1 52.7 0.38 11.2 6.1 4.5 2 1 2 4 4 4 0 Type III cell invasion protein SipB MscS_porin PF12795.7 VBB31614.1 - 9 5.8 82.3 6.9 6.1 36.8 3.5 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain SCO1-SenC PF02630.14 VBB31614.1 - 9.3 6.2 7.8 6.9 6.6 0.2 3.0 3 0 0 3 3 3 0 SCO1/SenC LLGL PF08366.13 VBB31615.1 - 2.2e-21 76.1 0.0 7.6e-21 74.4 0.0 2.0 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.32 VBB31615.1 - 1.2e-09 38.6 3.5 0.025 15.5 0.1 6.7 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31615.1 - 3e-09 37.1 0.3 0.029 14.7 0.0 5.4 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain G-patch_2 PF12656.7 VBB31617.1 - 1.1e-18 67.1 0.0 3.7e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 VBB31617.1 - 0.00013 21.8 0.0 0.047 13.7 0.0 2.7 2 0 0 2 2 2 2 KOW motif G-patch PF01585.23 VBB31617.1 - 0.001 18.9 0.7 0.0023 17.8 0.7 1.6 1 0 0 1 1 1 1 G-patch domain KN17_SH3 PF18131.1 VBB31617.1 - 0.0029 17.7 0.2 0.022 14.9 0.0 2.4 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain YajC PF02699.15 VBB31617.1 - 0.038 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit eIF-1a PF01176.19 VBB31618.1 - 2e-21 75.6 0.0 3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YL1 PF05764.13 VBB31618.1 - 2 8.5 11.7 2.8 8.0 11.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 VBB31618.1 - 2.8 5.9 13.3 3.4 5.6 13.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 VBB31618.1 - 4.9 5.2 11.6 5.7 5.0 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family COesterase PF00135.28 VBB31619.1 - 1.3e-130 436.7 0.0 1.7e-130 436.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB31619.1 - 3.4e-10 40.2 0.0 1e-09 38.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Met_10 PF02475.16 VBB31620.1 - 9.4e-40 136.5 0.0 2.1e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein tRNA-synt_2b PF00587.25 VBB31620.1 - 9.4e-26 90.9 0.0 2.2e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 VBB31620.1 - 6.3e-05 23.1 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TRM PF02005.16 VBB31620.1 - 0.00016 21.0 0.3 0.0007 18.9 0.3 2.0 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 VBB31620.1 - 0.039 14.6 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.6 VBB31622.1 - 1.3e-19 69.7 15.1 1.3e-06 28.0 0.1 5.3 4 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 VBB31622.1 - 1.2e-14 54.2 7.3 0.00079 19.8 0.0 5.7 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 VBB31622.1 - 0.0017 18.3 2.6 0.0068 16.4 0.1 2.9 2 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) fn3 PF00041.21 VBB31622.1 - 0.0041 17.4 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain LRR_6 PF13516.6 VBB31622.1 - 0.01 15.8 8.9 0.15 12.2 0.4 5.3 6 0 0 6 6 6 0 Leucine Rich repeat Izumo-Ig PF16706.5 VBB31622.1 - 0.013 15.5 0.1 0.043 13.9 0.1 1.8 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain ig PF00047.25 VBB31622.1 - 0.016 15.4 0.2 0.041 14.1 0.2 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 VBB31622.1 - 0.029 15.0 0.2 0.11 13.1 0.2 2.0 1 1 0 1 1 1 0 Immunoglobulin domain Comm PF15957.5 VBB31622.1 - 0.039 14.3 0.4 0.12 12.7 0.4 1.8 1 0 0 1 1 1 0 Commissureless LRR_1 PF00560.33 VBB31622.1 - 0.059 13.9 10.1 5.1 8.0 0.1 6.7 6 1 1 7 7 7 0 Leucine Rich Repeat I-set PF07679.16 VBB31622.1 - 0.087 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF3262 PF11660.8 VBB31622.1 - 0.27 11.6 2.5 0.53 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Wbp11 PF09429.10 VBB31623.1 - 0.00026 21.3 0.2 0.00026 21.3 0.2 2.9 2 1 1 3 3 3 1 WW domain binding protein 11 Sof1 PF04158.14 VBB31623.1 - 6.9 7.0 10.6 0.14 12.4 0.5 2.3 2 0 0 2 2 2 0 Sof1-like domain Med21 PF11221.8 VBB31623.1 - 8.6 6.6 8.3 4.7 7.5 2.7 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex ABC_membrane PF00664.23 VBB31624.1 - 8.4e-58 196.2 9.0 1.1e-57 195.8 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 VBB31624.1 - 8.5e-34 117.0 0.4 2e-33 115.8 0.1 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 VBB31624.1 - 1.7e-07 30.9 0.1 2e-06 27.4 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 VBB31624.1 - 0.00019 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 VBB31624.1 - 0.00093 19.6 0.6 0.012 16.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain ABC_ATPase PF09818.9 VBB31624.1 - 0.0033 16.3 0.0 0.0067 15.3 0.0 1.5 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 VBB31624.1 - 0.015 15.0 0.2 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 VBB31624.1 - 0.033 14.3 0.5 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 VBB31624.1 - 0.091 12.8 0.3 0.64 10.1 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 VBB31624.1 - 0.11 12.5 0.2 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 VBB31624.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Alkyl_sulf_dimr PF14863.6 VBB31624.1 - 0.12 12.9 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Zeta_toxin PF06414.12 VBB31624.1 - 0.13 11.5 0.2 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 VBB31624.1 - 0.14 12.5 0.7 0.47 10.7 0.6 2.0 1 1 0 1 1 1 0 AAA domain RRM_7 PF16367.5 VBB31625.1 - 6.5e-36 122.4 0.0 1.1e-32 112.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif CEBP_ZZ PF16366.5 VBB31625.1 - 8.2e-19 67.6 8.4 2.4e-18 66.1 8.4 1.9 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 VBB31625.1 - 1.8e-08 34.0 0.0 6.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1053 PF06327.14 VBB31625.1 - 0.47 11.0 5.1 0.13 12.9 1.5 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) HscB_4_cys PF18256.1 VBB31625.1 - 3.3 7.6 7.4 12 5.8 7.4 2.0 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif TMEM189_B_dmain PF10520.9 VBB31626.1 - 0.48 10.5 2.0 0.75 9.9 2.0 1.2 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain BUD22 PF09073.10 VBB31626.1 - 4.8 6.4 19.7 5.8 6.1 19.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 VBB31626.1 - 9.4 4.4 7.5 11 4.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein OTU PF02338.19 VBB31628.1 - 4.5e-12 46.6 0.0 3.5e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 VBB31628.1 - 0.0028 17.2 0.1 0.57 9.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain CUE PF02845.16 VBB31628.1 - 0.0086 15.8 0.8 0.045 13.5 0.2 2.6 3 0 0 3 3 3 1 CUE domain UBA_4 PF14555.6 VBB31628.1 - 0.45 10.4 0.0 0.45 10.4 0.0 2.2 3 0 0 3 3 3 0 UBA-like domain TSC22 PF01166.18 VBB31629.1 - 0.062 13.6 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family ACDC PF14733.6 VBB31629.1 - 4 7.8 8.2 0.94 9.8 0.6 3.5 3 0 0 3 3 3 0 AP2-coincident C-terminal MEIOC PF15189.6 VBB31630.1 - 6.8e-65 217.7 4.6 1.3e-64 216.8 4.6 1.4 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC CAMSAP_CC1 PF17095.5 VBB31630.1 - 0.00091 19.0 1.1 0.0022 17.8 1.1 1.6 1 0 0 1 1 1 1 Spectrin-binding region of Ca2+-Calmodulin PRIMA1 PF16101.5 VBB31630.1 - 6.2 6.9 15.3 17 5.4 15.3 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 VBB31630.1 - 9.8 5.6 12.8 5.9 6.3 10.1 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Fip1 PF05182.13 VBB31631.1 - 1.7e-23 81.9 0.9 2.8e-23 81.1 0.9 1.4 1 0 0 1 1 1 1 Fip1 motif PITH PF06201.13 VBB31632.1 - 3.1e-38 131.4 0.0 5.1e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 PITH domain EAP30 PF04157.16 VBB31632.1 - 2.5e-37 128.4 0.3 3.5e-37 128.0 0.3 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 VBB31632.1 - 9.7e-20 70.6 0.0 2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 RhoGEF PF00621.20 VBB31633.1 - 3e-38 131.9 2.9 6.3e-38 130.8 2.9 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 VBB31633.1 - 0.02 15.4 0.1 0.11 13.1 0.0 2.3 3 0 0 3 3 3 0 PH domain Metallophos PF00149.28 VBB31634.1 - 4.6e-33 115.4 0.0 6.5e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF236 PF03057.14 VBB31634.1 - 9e-23 79.9 0.3 3.2e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 DUF236 repeat STPPase_N PF16891.5 VBB31634.1 - 1.8e-15 57.1 0.1 4.1e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain NIF PF03031.18 VBB31636.1 - 7.7e-35 120.0 0.7 1.1e-34 119.5 0.7 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pox_LP_H2 PF03356.15 VBB31636.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral late protein H2 Occludin_ELL PF07303.13 VBB31636.1 - 0.16 12.7 1.8 0.41 11.4 0.2 2.1 2 0 0 2 2 2 0 Occludin homology domain BLI1 PF17324.2 VBB31636.1 - 0.19 12.4 1.0 0.3 11.8 0.1 1.8 2 0 0 2 2 2 0 BLOC-1 interactor 1 Peptidase_M28 PF04389.17 VBB31637.1 - 4.9e-42 143.9 0.0 6.8e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 VBB31637.1 - 0.0033 16.9 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Nicastrin PriCT_2 PF08707.11 VBB31637.1 - 1.2 9.5 5.1 3.9 7.9 0.3 3.0 3 1 0 3 3 3 0 Primase C terminal 2 (PriCT-2) Sod_Cu PF00080.20 VBB31638.1 - 8.5e-48 162.1 2.5 1.1e-47 161.8 2.5 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 VBB31639.1 - 3e-50 170.1 5.4 3.6e-50 169.8 5.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPT PF03151.16 VBB31640.1 - 7.7e-78 261.8 21.5 9.6e-78 261.5 21.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 VBB31640.1 - 1.6e-16 60.8 34.8 5.4e-10 39.6 8.5 2.6 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 VBB31640.1 - 0.057 12.6 19.3 0.09 12.0 19.3 1.4 1 0 0 1 1 1 0 UAA transporter family PCO_ADO PF07847.12 VBB31641.1 - 1e-23 83.9 0.0 1.2e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 VBB31641.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I AROS PF15684.5 VBB31642.1 - 0.0004 21.0 0.4 0.0004 21.0 0.4 1.8 2 0 0 2 2 2 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DUF3726 PF12525.8 VBB31642.1 - 0.088 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) Ribosomal_S30 PF04758.14 VBB31643.1 - 3.7e-29 100.7 8.7 4.5e-29 100.4 8.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 DUF3853 PF12964.7 VBB31643.1 - 0.05 13.8 1.1 0.11 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Ubiquitin_4 PF18036.1 VBB31643.1 - 0.058 13.4 0.4 11 6.1 0.0 2.6 2 1 1 3 3 3 0 Ubiquitin-like domain Fe-S_biosyn PF01521.20 VBB31644.1 - 8.7e-19 67.8 0.0 1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis BTG PF07742.12 VBB31644.1 - 0.096 12.5 0.0 14 5.6 0.0 2.2 1 1 1 2 2 2 0 BTG family AbiEi_1 PF09407.10 VBB31644.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain RMI1_N PF08585.12 VBB31645.1 - 8.1e-25 87.9 0.6 4.6e-17 62.5 0.1 2.7 1 1 1 2 2 2 2 RecQ mediated genome instability protein SMN PF06003.12 VBB31645.1 - 1.4e-05 24.5 0.5 6.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Tudor_2 PF18104.1 VBB31645.1 - 0.0041 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain tRNA_anti-codon PF01336.25 VBB31645.1 - 0.089 12.8 0.0 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain MOZ_SAS PF01853.18 VBB31646.1 - 2.9e-17 62.9 0.0 3.6e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family RepL PF05732.11 VBB31646.1 - 0.00037 20.0 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) GPR15L PF15854.5 VBB31647.1 - 1.6 9.0 4.4 11 6.4 0.1 3.5 3 0 0 3 3 3 0 G-protein coupled receptor ligand 15 SMC_N PF02463.19 VBB31648.1 - 5.6e-69 231.9 4.0 8.4e-69 231.3 4.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 VBB31648.1 - 9.1e-21 74.3 0.0 2.9e-20 72.7 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 VBB31648.1 - 1.1e-11 45.1 63.4 1.2e-10 41.7 21.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 VBB31648.1 - 1.2e-11 45.0 8.4 8.5e-06 25.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 VBB31648.1 - 7.9e-11 42.8 29.5 7.9e-11 42.8 29.5 7.4 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 VBB31648.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Seryl_tRNA_N PF02403.22 VBB31648.1 - 0.0078 16.4 7.5 0.0078 16.4 7.5 10.0 2 2 8 10 10 10 1 Seryl-tRNA synthetase N-terminal domain Fumble PF03630.14 VBB31648.1 - 0.92 8.6 4.9 0.31 10.2 0.7 2.4 2 0 0 2 2 2 0 Fumble ABC_tran PF00005.27 VBB31648.1 - 4.2 7.9 0.0 4.2 7.9 0.0 6.3 4 2 0 5 5 5 0 ABC transporter Kelch_5 PF13854.6 VBB31649.1 - 9.3e-32 108.5 0.4 0.0003 20.7 0.2 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 VBB31649.1 - 3e-25 87.9 2.4 3.9e-05 23.8 0.0 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 VBB31649.1 - 9.2e-24 83.2 0.0 0.00062 19.7 0.0 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 VBB31649.1 - 3.7e-22 77.8 1.4 0.0019 18.4 0.0 6.5 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 VBB31649.1 - 1.1e-19 69.7 1.1 0.018 14.6 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 VBB31649.1 - 2.5e-13 49.4 3.2 0.063 13.3 0.0 6.7 6 1 0 6 6 6 4 Kelch motif P16-Arc PF04699.14 VBB31650.1 - 2.6e-42 144.8 0.0 2.9e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 VBB31650.1 - 0.00044 20.5 0.0 0.00081 19.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PigN PF04987.14 VBB31651.1 - 3.7e-55 187.6 42.4 5.7e-49 167.2 33.6 2.3 1 1 1 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 VBB31651.1 - 3.2e-13 50.0 0.9 2e-05 24.4 0.4 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 VBB31651.1 - 1.7e-10 40.8 0.0 7e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 VBB31651.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Vps16_C PF04840.12 VBB31652.1 - 1.1e-09 37.8 3.8 2e-05 23.8 1.2 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region DUF4131 PF13567.6 VBB31653.1 - 0.01 15.5 0.4 0.01 15.5 0.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PHO4 PF01384.20 VBB31653.1 - 0.25 10.3 0.1 0.29 10.1 0.1 1.1 1 0 0 1 1 1 0 Phosphate transporter family HemY_N PF07219.13 VBB31653.1 - 1.2 9.3 3.5 2.7 8.2 0.5 2.3 2 0 0 2 2 2 0 HemY protein N-terminus zf-RING_2 PF13639.6 VBB31654.1 - 2.4e-11 43.8 7.8 4.6e-11 42.9 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 VBB31654.1 - 1.7e-07 31.4 10.7 8.7e-07 29.1 10.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB31654.1 - 6e-07 29.2 7.2 1.6e-06 27.9 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB31654.1 - 1.1e-06 28.5 4.0 2.7e-06 27.3 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 VBB31654.1 - 1.9e-06 27.5 2.6 4e-06 26.5 2.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 VBB31654.1 - 2.1e-06 27.4 7.1 4.4e-06 26.4 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 VBB31654.1 - 8.7e-06 25.3 2.5 1.8e-05 24.2 2.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 VBB31654.1 - 1.5e-05 24.9 6.9 3.4e-05 23.7 6.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 VBB31654.1 - 1.5e-05 24.8 6.4 4.4e-05 23.3 6.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB31654.1 - 0.00026 20.8 4.6 0.00059 19.6 4.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 VBB31654.1 - 0.0047 16.9 5.0 0.017 15.2 5.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 VBB31654.1 - 0.0055 16.9 2.4 0.014 15.6 2.4 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3H2C3 PF17122.5 VBB31654.1 - 0.045 13.8 1.3 0.1 12.7 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger zf-HC5HC2H PF13771.6 VBB31654.1 - 0.053 13.8 1.2 0.13 12.5 1.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 VBB31654.1 - 0.072 13.4 6.2 0.16 12.3 6.2 1.6 1 0 0 1 1 1 0 RING-like domain DUF4525 PF15027.6 VBB31654.1 - 0.078 12.7 0.1 0.26 11.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) zf-RING_6 PF14835.6 VBB31654.1 - 0.086 12.7 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.7 VBB31654.1 - 0.19 11.8 6.8 0.44 10.7 6.8 1.6 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 VBB31654.1 - 1.3 9.2 3.5 1.8 8.7 2.0 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_4 PF14570.6 VBB31654.1 - 2.3 8.1 4.8 4.6 7.1 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_5 PF13909.6 VBB31656.1 - 0.00016 21.3 2.2 0.0082 15.9 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 VBB31656.1 - 0.024 15.1 19.8 0.026 15.0 0.4 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB31656.1 - 0.72 10.8 16.1 0.5 11.3 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger XPG_I PF00867.18 VBB31658.1 - 1.2e-17 64.0 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 VBB31658.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain zf-C2H2 PF00096.26 VBB31659.1 - 1.6e-28 97.5 87.6 1.6e-05 25.1 0.5 11.4 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB31659.1 - 9.3e-26 88.3 83.1 0.0012 19.4 0.3 11.6 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB31659.1 - 1.3e-22 79.1 54.6 3.5e-08 33.5 0.2 10.7 11 0 0 11 11 11 5 Zinc-finger double domain zf-met PF12874.7 VBB31659.1 - 1.3e-13 50.8 56.4 0.0074 16.7 0.1 9.7 8 1 1 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB31659.1 - 6.1e-08 32.8 58.2 0.13 12.6 0.1 10.2 10 1 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 VBB31659.1 - 0.0037 17.0 0.1 0.0037 17.0 0.1 9.6 10 0 0 10 10 10 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 VBB31659.1 - 0.0097 16.2 63.0 1.3 9.4 0.9 10.3 6 3 4 10 10 10 5 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 VBB31659.1 - 1.1 9.3 66.2 0.51 10.4 0.8 9.6 9 0 0 9 9 9 0 C2H2-type zinc finger BolA PF01722.18 VBB31659.1 - 2.2 8.6 7.7 3.4 8.0 0.3 4.2 3 1 1 4 4 4 0 BolA-like protein zf-H2C2_5 PF13909.6 VBB31659.1 - 6.3 6.6 43.6 0.14 11.9 0.5 8.7 9 0 0 9 9 9 0 C2H2-type zinc-finger domain LRR_8 PF13855.6 VBB31660.1 - 6.8e-64 211.5 87.5 3.9e-16 58.5 1.1 6.3 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 VBB31660.1 - 1.6e-20 73.4 0.5 2.8e-12 46.7 0.1 2.7 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 VBB31660.1 - 4.1e-18 65.2 54.3 2.1e-06 28.0 2.2 8.0 2 2 9 11 11 11 11 Leucine Rich repeats (2 copies) LRRNT PF01462.18 VBB31660.1 - 7.1e-13 47.9 35.4 5.3e-09 35.5 5.4 4.7 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 VBB31660.1 - 1.1e-08 34.8 25.2 3.9e-06 26.5 3.2 4.0 2 2 2 4 4 4 3 Leucine-rich repeat LRRCT PF01463.24 VBB31660.1 - 0.0013 19.1 3.5 0.011 16.2 0.1 3.9 4 0 0 4 4 4 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 VBB31660.1 - 0.0018 18.6 44.9 0.062 13.9 0.0 11.5 10 3 3 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 VBB31660.1 - 0.15 12.2 0.1 0.15 12.2 0.1 8.8 11 0 0 11 11 11 0 Leucine Rich repeat Neur_chan_LBD PF02931.23 VBB31661.1 - 1.2e-38 132.8 2.5 1.6e-38 132.3 2.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB31661.1 - 2.5e-19 70.3 0.1 4e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Fructosamin_kin PF03881.14 VBB31662.1 - 3.1e-72 243.2 0.0 6.4e-72 242.2 0.0 1.4 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 VBB31662.1 - 3.8e-10 40.1 0.0 8.6e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB31662.1 - 0.00026 20.6 0.0 0.0029 17.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family AAA PF00004.29 VBB31663.1 - 5.7e-50 169.1 0.0 5.5e-40 136.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 VBB31663.1 - 5.7e-11 42.5 0.0 1.5e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 VBB31663.1 - 8.6e-10 38.3 0.1 1.8e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 VBB31663.1 - 1.4e-07 31.8 0.0 7.6e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 VBB31663.1 - 6.3e-07 29.1 0.2 5e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 VBB31663.1 - 2.8e-06 26.8 0.0 0.067 12.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 VBB31663.1 - 5e-06 26.8 0.1 0.0013 19.0 0.0 3.8 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.12 VBB31663.1 - 5.1e-06 26.3 0.1 0.017 14.9 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 VBB31663.1 - 7.8e-06 26.4 0.0 0.0083 16.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 VBB31663.1 - 1.9e-05 24.1 0.1 0.0074 15.7 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 VBB31663.1 - 2.2e-05 25.0 0.0 0.034 14.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 VBB31663.1 - 2.7e-05 23.6 0.3 0.0054 16.1 0.1 2.5 2 0 0 2 2 2 1 KaiC AAA_5 PF07728.14 VBB31663.1 - 4.3e-05 23.5 0.3 0.0013 18.7 0.2 3.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 VBB31663.1 - 7.6e-05 22.5 0.0 0.04 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 VBB31663.1 - 0.00012 22.2 0.0 0.17 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 VBB31663.1 - 0.00014 21.9 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 VBB31663.1 - 0.00022 21.6 0.0 0.043 14.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 VBB31663.1 - 0.00026 21.2 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 VBB31663.1 - 0.0009 18.8 0.1 0.022 14.3 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region ATPase_2 PF01637.18 VBB31663.1 - 0.0011 18.9 0.0 4.3 7.2 0.0 3.5 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 VBB31663.1 - 0.0015 18.3 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 VBB31663.1 - 0.0016 18.3 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 VBB31663.1 - 0.0028 17.6 0.2 3.2 7.6 0.0 4.0 4 0 0 4 4 4 1 NACHT domain KTI12 PF08433.10 VBB31663.1 - 0.004 16.7 0.0 3.5 7.0 0.0 2.6 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Parvo_NS1 PF01057.17 VBB31663.1 - 0.006 15.7 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 VBB31663.1 - 0.0064 16.2 0.0 0.24 11.1 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein CPT PF07931.12 VBB31663.1 - 0.0081 16.0 0.3 0.74 9.6 0.0 3.3 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 VBB31663.1 - 0.014 15.0 0.9 1.7 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 VBB31663.1 - 0.03 14.8 0.1 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 VBB31663.1 - 0.03 13.6 0.0 0.87 8.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 VBB31663.1 - 0.056 12.5 0.0 6.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 VBB31663.1 - 0.064 13.0 0.3 0.22 11.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 VBB31663.1 - 0.15 12.4 0.8 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 VBB31664.1 - 1.8e-16 60.3 0.0 6.8e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31664.1 - 5.4e-11 42.3 0.0 2.9e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB31664.1 - 0.0041 16.5 0.0 0.25 10.6 0.0 2.7 2 1 1 3 3 3 1 Kinase-like WAC_Acf1_DNA_bd PF10537.9 VBB31664.1 - 0.068 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal ACBP PF00887.19 VBB31665.1 - 1.8e-17 63.3 0.1 2.2e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein MADF_DNA_bdg PF10545.9 VBB31666.1 - 1.7e-14 53.9 4.0 1.7e-14 53.9 4.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB31666.1 - 9.7e-06 25.9 3.3 2.1e-05 24.8 3.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 VBB31666.1 - 0.0032 17.5 2.4 0.012 15.6 2.4 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 VBB31666.1 - 0.29 12.1 3.1 0.68 11.0 3.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TMC PF07810.13 VBB31667.1 - 1.8e-36 125.1 4.1 2.9e-36 124.4 2.1 2.5 2 0 0 2 2 2 1 TMC domain Ac76 PF05814.11 VBB31667.1 - 4.9 7.2 10.1 2.4 8.2 0.1 4.6 5 0 0 5 5 5 0 Orf76 (Ac76) KASH PF10541.9 VBB31667.1 - 5.9 7.2 6.7 3.1 8.1 0.3 3.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain Ribosomal_L7Ae PF01248.26 VBB31668.1 - 2e-12 46.7 0.4 4.8e-12 45.4 0.4 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AMP-binding PF00501.28 VBB31671.1 - 3.6e-91 305.9 0.0 4.8e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB31671.1 - 0.004 18.1 0.0 0.0085 17.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2247 PF10004.9 VBB31671.1 - 0.087 12.6 0.6 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) DnaJ PF00226.31 VBB31672.1 - 3.6e-15 55.8 0.5 7.9e-15 54.7 0.5 1.6 1 1 0 1 1 1 1 DnaJ domain UPF0767 PF15990.5 VBB31672.1 - 1.2e-07 31.8 0.2 3e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 UPF0767 family Phage_CI_repr PF07022.13 VBB31672.1 - 0.047 13.8 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DnaJ PF00226.31 VBB31673.1 - 8.5e-19 67.4 3.4 1.9e-18 66.3 3.4 1.6 1 0 0 1 1 1 1 DnaJ domain Collagen PF01391.18 VBB31674.1 - 7.5e-21 73.7 75.5 1e-08 34.8 28.8 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB31674.1 - 0.013 15.5 1.0 0.022 14.8 0.1 1.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Mucin PF01456.17 VBB31674.1 - 6.4 6.8 13.1 11 6.0 13.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dcc1 PF09724.9 VBB31676.1 - 1.1e-39 136.7 1.0 1.3e-39 136.5 1.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 zf-RING_9 PF13901.6 VBB31676.1 - 0.038 14.0 0.2 0.051 13.6 0.2 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SARS_lipid_bind PF09399.10 VBB31677.1 - 0.049 13.8 0.1 85 3.4 0.0 4.7 1 1 2 5 5 5 0 SARS lipid binding protein Spo0M PF07070.11 VBB31677.1 - 0.13 11.8 0.2 20 4.6 0.0 3.2 1 1 1 3 3 3 0 SpoOM protein UBA_3 PF09288.10 VBB31677.1 - 2.6 7.9 7.1 44 4.0 0.1 3.9 1 1 1 4 4 4 0 Fungal ubiquitin-associated domain TSP_1 PF00090.19 VBB31678.1 - 4.1e-11 42.9 34.8 5.3e-06 26.5 11.2 3.3 3 0 0 3 3 3 3 Thrombospondin type 1 domain AMP-binding PF00501.28 VBB31679.1 - 2.1e-46 158.4 0.1 1.6e-26 92.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 VBB31679.1 - 9.3e-09 36.1 0.0 1.6e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Laminin_EGF PF00053.24 VBB31680.1 - 2.6e-95 312.4 257.3 2.6e-10 40.3 12.5 15.2 14 1 1 15 15 15 14 Laminin EGF domain Laminin_N PF00055.17 VBB31680.1 - 4.8e-80 268.5 0.3 2.2e-79 266.4 0.3 2.3 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) F5_F8_type_C PF00754.25 VBB31680.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain DUF155 PF02582.14 VBB31680.1 - 2.7 8.1 12.1 1.8 8.6 0.8 2.7 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 GARP PF16731.5 VBB31680.1 - 7 6.3 46.5 0.33 10.6 13.9 4.5 2 1 2 4 4 4 0 Glutamic acid/alanine-rich protein of Trypanosoma zf-BED PF02892.15 VBB31681.1 - 7.5e-13 48.3 1.5 1.9e-12 47.0 1.5 1.7 1 0 0 1 1 1 1 BED zinc finger H-kinase_dim PF02895.14 VBB31681.1 - 0.011 16.1 0.1 0.069 13.5 0.0 2.3 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Arf PF00025.21 VBB31682.1 - 8.1e-41 139.4 0.1 9.2e-41 139.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB31682.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB31682.1 - 1.6e-17 63.6 0.0 1.8e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 VBB31682.1 - 1.6e-10 40.7 0.2 6.8e-07 28.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 VBB31682.1 - 1.1e-09 38.0 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB31682.1 - 3.6e-09 36.7 0.0 5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 VBB31682.1 - 7.6e-09 35.3 0.0 8.8e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 VBB31682.1 - 0.00024 21.2 0.1 0.32 11.1 0.1 2.1 1 1 1 2 2 2 2 Dynamin family VirE PF05272.11 VBB31682.1 - 0.0056 16.4 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Virulence-associated protein E FeoB_N PF02421.18 VBB31682.1 - 0.0078 15.7 0.3 0.17 11.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 VBB31682.1 - 0.014 14.9 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 VBB31682.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 VBB31682.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 VBB31682.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain I-set PF07679.16 VBB31683.1 - 9.6e-10 38.4 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 VBB31683.1 - 0.00028 21.0 0.0 0.002 18.2 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 VBB31683.1 - 0.00028 21.4 0.0 0.00032 21.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 VBB31683.1 - 0.0099 16.1 0.1 0.011 15.9 0.1 1.1 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Ig_2 PF13895.6 VBB31683.1 - 0.021 15.2 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain DUF3456 PF11938.8 VBB31684.1 - 2.6e-13 50.8 4.2 1.4e-06 28.9 1.1 2.5 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP EGF_CA PF07645.15 VBB31684.1 - 6.9e-08 32.6 11.4 6.9e-08 32.6 11.4 5.3 3 1 1 4 4 4 1 Calcium-binding EGF domain Laminin_EGF PF00053.24 VBB31684.1 - 0.0053 16.9 9.8 0.0053 16.9 9.8 5.3 2 1 3 5 5 5 1 Laminin EGF domain cEGF PF12662.7 VBB31684.1 - 0.66 10.0 25.6 1.1 9.3 0.2 5.0 3 1 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 VBB31684.1 - 1.5 9.6 31.7 0.19 12.4 3.2 5.1 5 0 0 5 5 5 0 Human growth factor-like EGF PDZ_6 PF17820.1 VBB31685.1 - 0.0014 18.5 0.1 0.0019 18.0 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB31685.1 - 0.0083 16.5 0.0 0.0096 16.3 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Thiolase_N PF00108.23 VBB31686.1 - 1.3e-19 70.6 0.9 1.3e-18 67.4 0.9 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain SCP2 PF02036.17 VBB31686.1 - 9.1e-18 64.6 0.1 2.1e-17 63.4 0.1 1.6 2 0 0 2 2 2 1 SCP-2 sterol transfer family Thiolase_C PF02803.18 VBB31686.1 - 1.6e-11 43.9 0.5 1.4e-10 40.9 0.0 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain Alkyl_sulf_C PF14864.6 VBB31686.1 - 0.00041 20.6 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ketoacyl-synt PF00109.26 VBB31686.1 - 0.00049 19.7 0.5 0.0011 18.6 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 VBB31686.1 - 0.0054 16.7 0.2 0.95 9.5 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 VBB31686.1 - 0.0067 15.2 0.3 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 VBB31686.1 - 0.036 13.9 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PH PF00169.29 VBB31687.1 - 1.4e-10 41.6 0.1 2.4e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 PH domain DUF2076 PF09849.9 VBB31687.1 - 0.00057 20.0 4.5 0.00098 19.2 4.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Kunitz_BPTI PF00014.23 VBB31688.1 - 1.2e-119 390.5 98.0 1.9e-18 66.4 5.8 7.2 7 0 0 7 7 7 7 Kunitz/Bovine pancreatic trypsin inhibitor domain Ig_3 PF13927.6 VBB31688.1 - 0.0054 17.3 0.6 0.029 15.0 0.0 2.6 4 0 0 4 4 4 1 Immunoglobulin domain Ig_2 PF13895.6 VBB31688.1 - 0.0087 16.4 0.0 0.03 14.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain SAD_SRA PF02182.17 VBB31688.1 - 0.12 12.0 5.3 11 5.6 0.6 4.1 2 1 2 4 4 4 0 SAD/SRA domain MAAL_N PF05034.13 VBB31688.1 - 0.15 11.7 1.4 41 3.8 0.0 3.6 4 0 0 4 4 4 0 Methylaspartate ammonia-lyase N-terminus NAT PF04768.13 VBB31688.1 - 0.32 10.6 3.6 3 7.5 0.1 3.4 4 0 0 4 4 4 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase HSP20 PF00011.21 VBB31690.1 - 2.4e-10 40.5 0.0 6e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB31690.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA PSP PF04046.16 VBB31691.1 - 2.3e-14 53.0 0.1 4.1e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 PSP Synaphin PF05835.12 VBB31691.1 - 0.39 11.0 4.6 0.87 9.9 4.6 1.6 1 0 0 1 1 1 0 Synaphin protein Snapin_Pallidin PF14712.6 VBB31693.1 - 1.5 9.3 6.1 0.26 11.7 1.6 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Neur_chan_LBD PF02931.23 VBB31694.1 - 3.8e-38 131.1 5.5 5.2e-38 130.6 5.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB31694.1 - 3.1e-21 76.5 0.6 4.8e-21 75.9 0.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 VBB31694.1 - 0.068 14.1 0.0 0.12 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2457 PF10446.9 VBB31694.1 - 1.2 8.2 5.4 1.6 7.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DEAD PF00270.29 VBB31695.1 - 5.1e-44 150.1 0.1 9e-44 149.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31695.1 - 1.2e-31 109.3 0.0 7.5e-31 106.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 VBB31695.1 - 0.00012 21.8 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 VBB31695.1 - 0.00021 21.6 0.0 0.0068 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 VBB31695.1 - 0.00062 19.8 0.1 0.0012 18.9 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 VBB31695.1 - 0.0023 16.8 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 VBB31695.1 - 0.039 14.2 0.4 0.28 11.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain DUF3419 PF11899.8 VBB31695.1 - 0.11 11.7 0.0 0.8 8.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3419) CCDC32 PF14989.6 VBB31696.1 - 1e-09 38.6 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing 32 UCH PF00443.29 VBB31697.1 - 1.8e-37 129.2 0.0 1e-34 120.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase OTU PF02338.19 VBB31697.1 - 1.4e-10 41.8 0.1 1.6e-09 38.3 0.0 2.5 2 0 0 2 2 2 1 OTU-like cysteine protease UCH_1 PF13423.6 VBB31697.1 - 7.1e-09 35.7 19.8 2e-07 30.9 5.0 3.8 3 1 1 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase Zn_Tnp_IS91 PF14319.6 VBB31697.1 - 9.1 6.4 7.4 8.1 6.6 0.0 3.4 3 0 0 3 3 3 0 Transposase zinc-binding domain DUF4333 PF14230.6 VBB31698.1 - 0.016 15.4 0.1 0.038 14.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) DUF4815 PF16075.5 VBB31698.1 - 0.12 10.7 0.5 0.18 10.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) DUF4062 PF13271.6 VBB31698.1 - 0.12 12.8 0.3 0.51 10.7 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) AAA_5 PF07728.14 VBB31698.1 - 0.13 12.3 0.1 1.2 9.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) zf-C2H2_12 PF18658.1 VBB31698.1 - 0.2 11.2 13.6 0.25 10.9 0.4 3.9 2 1 0 3 3 3 0 Zinc-finger C2H2-type C1_2 PF03107.16 VBB31698.1 - 0.36 11.2 9.8 0.82 10.0 0.8 3.6 2 2 0 2 2 2 0 C1 domain zf-C2H2_4 PF13894.6 VBB31698.1 - 0.64 11.0 23.2 0.88 10.6 0.2 5.6 6 0 0 6 6 5 0 C2H2-type zinc finger IFT20 PF14931.6 VBB31698.1 - 0.93 9.7 9.0 1.6 8.9 0.0 4.0 4 0 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 Zn_ribbon_SprT PF17283.2 VBB31698.1 - 1.3 9.0 13.2 2.7 7.9 3.0 3.4 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF2256 PF10013.9 VBB31698.1 - 2.5 8.3 6.4 0.33 11.1 0.5 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Rubredoxin_2 PF18073.1 VBB31698.1 - 3.5 7.4 7.0 17 5.2 0.4 3.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain DDE_3 PF13358.6 VBB31699.1 - 0.064 13.0 0.7 14 5.4 0.0 2.8 2 1 0 2 2 2 0 DDE superfamily endonuclease GTP_EFTU PF00009.27 VBB31700.1 - 1.2e-55 188.1 0.0 1.7e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 VBB31700.1 - 3.7e-41 139.9 0.0 9.4e-41 138.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 VBB31700.1 - 1.3e-15 57.5 1.3 2.8e-15 56.4 0.2 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 VBB31700.1 - 0.00011 22.3 0.1 0.003 17.6 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 VBB31700.1 - 0.017 15.0 1.9 0.02 14.8 0.3 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 VBB31700.1 - 0.047 13.8 0.3 0.13 12.3 0.1 1.8 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Dynamin_N PF00350.23 VBB31700.1 - 0.09 12.8 0.0 17 5.4 0.1 2.6 2 0 0 2 2 2 0 Dynamin family SRP54 PF00448.22 VBB31702.1 - 2e-08 34.1 0.2 3e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF763 PF05559.11 VBB31702.1 - 0.08 12.1 0.1 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Cast PF10174.9 VBB31703.1 - 1.8e-19 69.5 69.6 3.5e-16 58.7 30.2 2.0 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone EMC1_C PF07774.13 VBB31703.1 - 0.24 11.0 5.0 0.078 12.6 0.7 2.1 2 0 0 2 2 2 0 ER membrane protein complex subunit 1, C-terminal rve_3 PF13683.6 VBB31703.1 - 0.93 9.3 4.0 2.1 8.2 0.1 3.4 3 0 0 3 3 3 0 Integrase core domain Endotoxin_N PF03945.14 VBB31703.1 - 6.2 6.5 7.8 0.51 10.0 0.1 2.5 2 1 1 3 3 3 0 delta endotoxin, N-terminal domain UPRTase PF14681.6 VBB31704.1 - 3e-69 232.6 0.1 4.7e-69 232.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 VBB31704.1 - 5.6e-59 199.2 0.0 8.5e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 VBB31704.1 - 9.4e-08 32.7 0.0 1.9e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 VBB31704.1 - 4.6e-05 23.9 0.4 1.2 9.6 0.1 3.2 3 0 0 3 3 3 2 AAA domain CPT PF07931.12 VBB31704.1 - 6.2e-05 22.9 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 VBB31704.1 - 0.00015 21.9 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 VBB31704.1 - 0.00043 20.0 0.2 0.0028 17.4 0.2 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase Cytidylate_kin PF02224.18 VBB31704.1 - 0.00088 19.1 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 Cytidylate kinase Zeta_toxin PF06414.12 VBB31704.1 - 0.087 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 VBB31704.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 VBB31704.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sema PF01403.19 VBB31705.1 - 2.1e-12 46.6 0.0 2.5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Sema domain HAP1_N PF04849.13 VBB31706.1 - 4.1e-40 137.9 36.0 1e-39 136.6 36.0 1.5 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DUF452 PF04301.13 VBB31706.1 - 0.016 14.8 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF452) CwsA PF10814.8 VBB31706.1 - 0.024 14.8 1.1 0.18 12.0 0.4 2.3 2 1 0 2 2 2 0 Cell wall synthesis protein CwsA BLOC1_2 PF10046.9 VBB31706.1 - 0.048 14.0 15.8 0.96 9.8 6.6 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lebercilin PF15619.6 VBB31706.1 - 0.066 12.9 27.0 0.019 14.6 17.0 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BST2 PF16716.5 VBB31706.1 - 0.068 13.8 25.5 0.09 13.4 7.3 3.6 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 FIVAR PF07554.13 VBB31706.1 - 0.13 13.0 4.0 0.12 13.2 1.9 2.1 2 0 0 2 2 1 0 FIVAR domain TMF_TATA_bd PF12325.8 VBB31706.1 - 0.4 10.9 27.9 8.2 6.7 19.7 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4485 PF14846.6 VBB31706.1 - 0.48 10.5 5.0 0.5 10.5 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4485) DUF4200 PF13863.6 VBB31706.1 - 0.56 10.6 27.6 0.79 10.1 12.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 VBB31706.1 - 0.62 10.6 32.9 0.85 10.1 7.9 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PI_PP_I PF18363.1 VBB31706.1 - 0.68 10.2 7.3 0.32 11.2 2.2 2.5 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain Ax_dynein_light PF10211.9 VBB31706.1 - 0.77 9.7 26.9 0.14 12.1 10.2 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain ZapB PF06005.12 VBB31706.1 - 0.81 10.2 32.2 4 8.0 10.2 3.4 3 0 0 3 3 3 0 Cell division protein ZapB CdvA PF18822.1 VBB31706.1 - 0.83 9.5 26.4 1.1 9.1 4.0 4.0 2 1 2 4 4 4 0 CdvA-like coiled-coil domain TSC22 PF01166.18 VBB31706.1 - 0.89 9.9 24.6 0.55 10.6 3.5 4.2 3 1 1 4 4 4 0 TSC-22/dip/bun family Spc7 PF08317.11 VBB31706.1 - 0.9 8.4 28.2 0.15 10.9 11.4 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein bZIP_1 PF00170.21 VBB31706.1 - 0.9 9.7 26.7 1.9 8.7 8.1 4.1 4 1 1 5 5 5 0 bZIP transcription factor CREPT PF16566.5 VBB31706.1 - 1.1 9.4 21.4 0.085 13.0 8.7 2.8 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour AKAP95 PF04988.12 VBB31706.1 - 1.2 9.3 8.2 0.9 9.8 4.0 2.1 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Fez1 PF06818.15 VBB31706.1 - 1.6 9.2 23.3 2 8.8 12.5 2.2 1 1 1 2 2 2 0 Fez1 Spc24 PF08286.11 VBB31706.1 - 3.1 8.1 23.6 3.1 8.1 6.9 3.6 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Tn7_Tnp_TnsA_C PF08721.11 VBB31706.1 - 5.5 7.7 11.7 0.49 11.1 1.9 3.1 2 1 2 4 4 3 0 TnsA endonuclease C terminal GAS PF13851.6 VBB31706.1 - 6.4 6.1 32.8 5.8 6.2 8.7 3.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 VBB31706.1 - 7.2 7.3 26.8 9.7 6.9 6.7 3.6 2 1 2 4 4 4 0 Initiation control protein YabA Occludin_ELL PF07303.13 VBB31706.1 - 7.4 7.4 14.9 0.59 10.9 4.1 3.4 1 1 3 4 4 4 0 Occludin homology domain Prefoldin PF02996.17 VBB31706.1 - 9.1 6.2 23.9 7.3 6.5 4.6 4.1 3 1 1 4 4 4 0 Prefoldin subunit Peptidase_C1 PF00112.23 VBB31707.1 - 9.6e-23 81.4 7.4 1.4e-22 80.8 7.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 VBB31707.1 - 2e-05 24.4 0.4 5.3e-05 23.0 0.4 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide Pkinase PF00069.25 VBB31710.1 - 1.2e-19 70.7 0.0 4.9e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31710.1 - 1.5e-07 31.0 0.0 3.4e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31710.1 - 7.3e-05 21.7 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB31710.1 - 0.081 12.8 0.0 24 4.8 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 VBB31710.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 VBB31711.1 - 4e-18 65.8 2.1 1.7e-10 41.3 1.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 VBB31711.1 - 5.1e-18 64.6 0.2 5.4e-05 23.4 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 VBB31711.1 - 1.4e-16 58.9 0.6 3.9e-05 23.7 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 VBB31711.1 - 4.5e-15 55.8 0.5 2.7e-06 27.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB31711.1 - 1.4e-11 44.4 0.0 4.6e-07 30.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 VBB31711.1 - 4.4e-05 22.8 34.6 0.0004 19.7 34.6 2.1 1 1 0 1 1 1 1 Ion transport protein PRELI PF04707.14 VBB31712.1 - 3.6e-40 137.4 0.1 8.7e-40 136.1 0.1 1.7 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 VBB31712.1 - 1.4e-39 135.3 0.0 2.7e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 VBB31712.1 - 3.7e-06 27.0 0.1 1.2e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EGF PF00008.27 VBB31714.1 - 2.5e-41 139.6 206.8 1.4e-07 31.6 5.3 16.7 16 0 0 16 16 16 11 EGF-like domain Laminin_G_2 PF02210.24 VBB31714.1 - 6.3e-29 101.1 3.9 3.4e-16 60.0 0.1 3.7 3 1 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 VBB31714.1 - 3.5e-25 88.7 0.9 2.9e-16 59.9 0.0 4.0 3 1 0 3 3 3 3 Laminin G domain hEGF PF12661.7 VBB31714.1 - 2.7e-12 46.8 189.9 0.00088 19.8 1.7 17.3 17 0 0 17 17 17 11 Human growth factor-like EGF EGF_CA PF07645.15 VBB31714.1 - 2.5e-07 30.8 6.8 2.5e-07 30.8 6.8 17.3 8 5 9 17 17 17 3 Calcium-binding EGF domain EGF_2 PF07974.13 VBB31714.1 - 0.00024 21.4 10.5 0.00024 21.4 10.5 16.8 16 1 0 16 16 16 10 EGF-like domain EGF_3 PF12947.7 VBB31714.1 - 0.00029 20.9 18.2 0.00041 20.5 2.5 17.6 12 5 5 17 17 17 6 EGF domain Spt20 PF12090.8 VBB31716.1 - 0.0042 16.7 23.7 0.0042 16.7 23.7 4.4 4 0 0 4 4 4 1 Spt20 family Dopey_N PF04118.14 VBB31716.1 - 0.27 10.3 7.4 0.71 8.9 3.5 2.6 2 1 0 2 2 2 0 Dopey, N-terminal Coilin_N PF15862.5 VBB31716.1 - 2.9 7.7 20.1 0.017 15.0 8.3 3.0 2 0 0 2 2 2 0 Coilin N-terminus PP2C_C PF07830.13 VBB31716.1 - 4.6 7.8 5.9 0.55 10.7 0.2 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain ILEI PF15711.5 VBB31717.1 - 7.5e-36 122.5 0.7 1.2e-25 89.8 0.0 2.5 2 0 0 2 2 2 2 Interleukin-like EMT inducer AP-5_subunit_s1 PF15001.6 VBB31718.1 - 0.15 12.1 0.3 0.16 11.9 0.3 1.0 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Methyltransf_25 PF13649.6 VBB31719.1 - 2e-10 41.2 0.0 7e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 VBB31719.1 - 5e-10 39.9 0.0 6.9e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 VBB31719.1 - 3.7e-08 33.3 0.2 8.6e-06 25.6 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 VBB31719.1 - 0.00041 21.0 0.0 0.035 14.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 VBB31719.1 - 0.0013 18.2 0.0 0.0052 16.2 0.0 2.0 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 VBB31719.1 - 0.0041 17.0 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 VBB31719.1 - 0.02 14.1 0.4 0.063 12.4 0.1 1.8 2 0 0 2 2 2 0 O-methyltransferase MTS PF05175.14 VBB31719.1 - 0.038 13.5 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase small domain TusA PF01206.17 VBB31719.1 - 0.062 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Sulfurtransferase TusA Pkinase_Tyr PF07714.17 VBB31720.1 - 1.1e-75 254.3 0.0 1.6e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB31720.1 - 7.2e-47 160.0 0.0 1.4e-46 159.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DNTTIP1_dimer PF18192.1 VBB31720.1 - 2.1e-20 72.8 0.0 5.5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain AT_hook PF02178.19 VBB31720.1 - 0.014 15.2 1.7 0.036 13.9 1.7 1.7 1 0 0 1 1 1 0 AT hook motif Kinase-like PF14531.6 VBB31720.1 - 0.046 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Citrate_bind PF16114.5 VBB31721.1 - 1.7e-86 288.2 0.1 2.9e-86 287.5 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 VBB31721.1 - 2.3e-20 73.0 0.0 1.1e-18 67.5 0.0 2.5 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 VBB31721.1 - 1.8e-17 63.5 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 VBB31721.1 - 5.6e-13 49.4 0.0 1.4e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 VBB31721.1 - 2.6e-06 27.2 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 VBB31721.1 - 0.0014 18.4 0.0 0.0094 15.8 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain SAP30_Sin3_bdg PF13867.6 VBB31722.1 - 8.2e-15 54.9 0.3 8.2e-15 54.9 0.3 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 VBB31722.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.3 3 0 0 3 3 3 0 SAP30 zinc-finger OmpH PF03938.14 VBB31722.1 - 3.5 8.0 22.1 0.22 11.9 15.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GAGA_bind PF06217.12 VBB31722.1 - 5.4 7.2 13.0 1.3 9.2 8.1 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Glyco_hydro_85 PF03644.13 VBB31723.1 - 4.3e-77 259.5 1.1 6.2e-77 259.0 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF3456 PF11938.8 VBB31723.1 - 2.5e-15 57.3 0.6 6.6e-15 56.0 0.6 1.7 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Cathelicidins PF00666.17 VBB31723.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Cathelicidin Fer2 PF00111.27 VBB31723.1 - 0.45 10.5 2.5 0.38 10.7 0.3 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain PDZ PF00595.24 VBB31724.1 - 1.8e-05 25.0 0.0 4.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB31724.1 - 0.012 15.4 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 0 PDZ domain PDZ_2 PF13180.6 VBB31724.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Mod_r PF07200.13 VBB31725.1 - 4.9e-33 114.3 13.9 9e-33 113.4 11.3 2.1 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein CelTOS PF18659.1 VBB31725.1 - 0.26 11.7 3.1 0.22 12.0 1.1 1.9 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites DUF1827 PF08860.10 VBB31725.1 - 1.1 9.5 3.6 41 4.5 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1827) RecG_N PF17190.4 VBB31725.1 - 1.9 9.3 7.3 2.9 8.7 0.0 3.4 3 0 0 3 3 3 0 RecG N-terminal helical domain V_ATPase_I PF01496.19 VBB31725.1 - 5.3 4.8 6.1 7.6 4.3 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IKI3 PF04762.12 VBB31726.1 - 1.8e-158 529.3 0.0 3.1e-158 528.6 0.0 1.4 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 VBB31726.1 - 2.2e-06 27.8 0.0 0.3 11.4 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 VBB31726.1 - 0.011 15.6 8.2 0.11 12.4 0.3 4.1 2 1 1 3 3 3 0 Region in Clathrin and VPS RasGEF PF00617.19 VBB31727.1 - 0.0049 17.1 0.8 0.015 15.5 0.1 2.3 2 1 0 2 2 2 1 RasGEF domain TRAPPC10 PF12584.8 VBB31727.1 - 0.011 15.5 0.0 0.037 13.7 0.0 1.9 1 1 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 DLEU7 PF15760.5 VBB31727.1 - 0.2 11.1 0.0 0.84 9.1 0.0 1.9 2 0 0 2 2 2 0 Leukemia-associated protein 7 TFIIA PF03153.13 VBB31728.1 - 1.7 8.6 8.5 1.9 8.4 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pro_isomerase PF00160.21 VBB31729.1 - 5.3e-46 156.8 0.4 1.1e-45 155.8 0.4 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SF1-HH PF16275.5 VBB31729.1 - 2.8e-27 95.3 1.6 7e-25 87.6 0.5 3.2 3 1 1 4 4 4 2 Splicing factor 1 helix-hairpin domain RRM_1 PF00076.22 VBB31729.1 - 6.2e-19 67.6 0.0 1.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 VBB31729.1 - 5.3e-07 29.4 0.1 1.2e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 VBB31729.1 - 0.0004 20.3 1.1 0.0004 20.3 1.1 3.3 4 0 0 4 4 4 1 Zinc knuckle Presenilin PF01080.17 VBB31729.1 - 0.0078 15.0 9.0 0.013 14.3 9.0 1.3 1 0 0 1 1 1 1 Presenilin zf-CCHC_3 PF13917.6 VBB31729.1 - 0.016 15.1 0.4 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Zinc knuckle Apt1 PF10351.9 VBB31729.1 - 0.31 9.9 19.4 0.48 9.2 19.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 VBB31729.1 - 1.8 7.0 12.6 2.4 6.6 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Kelch_1 PF01344.25 VBB31730.1 - 1.4e-79 261.5 14.3 7.2e-17 60.7 0.7 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 VBB31730.1 - 4.4e-47 156.9 3.4 1.1e-08 35.0 0.0 6.4 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 VBB31730.1 - 9.4e-28 96.3 0.2 2.1e-27 95.2 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 VBB31730.1 - 2.1e-27 94.0 6.5 3.3e-07 30.0 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 VBB31730.1 - 5.6e-26 90.3 5.7 1.6e-05 24.8 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 VBB31730.1 - 1.4e-24 86.4 0.5 2.6e-24 85.6 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 VBB31730.1 - 1.1e-19 70.2 12.9 0.0035 17.6 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 VBB31730.1 - 4.6e-06 26.5 6.4 4.4 7.4 0.0 5.7 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 VBB31730.1 - 0.0069 16.6 0.5 0.076 13.2 0.0 2.5 2 1 0 3 3 3 1 Domain of unknown function (DUF3342) Acetyltransf_1 PF00583.25 VBB31731.1 - 8.5e-15 55.0 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB31731.1 - 3.7e-08 33.4 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 VBB31731.1 - 9e-08 32.4 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 VBB31731.1 - 0.0032 17.5 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 VBB31731.1 - 0.049 13.8 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3263 PF11662.8 VBB31731.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Acetyltransf_CG PF14542.6 VBB31731.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TTR-52 PF01060.23 VBB31733.1 - 5e-25 88.0 0.0 5.7e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family LRR_8 PF13855.6 VBB31734.1 - 7.7e-10 38.4 0.0 1.9e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_5 PF13306.6 VBB31734.1 - 0.00043 20.2 0.3 0.00062 19.7 0.3 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB31734.1 - 0.039 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Tetraspanin PF00335.20 VBB31735.1 - 5.8e-17 62.2 16.5 8.7e-15 55.1 12.2 2.6 2 1 0 2 2 2 1 Tetraspanin family EspA PF03433.13 VBB31735.1 - 0.061 13.2 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 EspA-like secreted protein NDUF_B12 PF08122.12 VBB31735.1 - 0.17 12.0 0.5 0.57 10.3 0.5 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family zf-C3HC4_3 PF13920.6 VBB31736.1 - 1.5e-09 37.6 9.4 2.4e-09 36.9 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB31736.1 - 2.9e-09 37.1 13.9 2.9e-09 37.1 13.9 1.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 VBB31736.1 - 1.1e-08 34.9 11.2 2.6e-08 33.7 11.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB31736.1 - 2.6e-08 33.6 13.9 5.2e-08 32.6 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB31736.1 - 5.8e-07 29.7 8.6 1.2e-06 28.6 8.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB31736.1 - 6.7e-07 29.1 14.3 1.1e-06 28.4 14.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 VBB31736.1 - 2.2e-06 27.4 10.2 3.7e-06 26.7 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 VBB31736.1 - 2.4e-06 27.4 12.6 4.1e-06 26.7 12.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 VBB31736.1 - 1.6e-05 24.9 13.5 2.9e-05 24.1 13.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 VBB31736.1 - 0.00044 20.3 4.4 0.00082 19.4 4.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 VBB31736.1 - 0.058 13.5 5.9 0.11 12.7 5.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 VBB31736.1 - 0.068 13.0 5.4 0.13 12.1 5.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 VBB31736.1 - 0.11 12.4 5.0 0.22 11.4 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 VBB31736.1 - 0.67 9.6 8.8 1.4 8.6 8.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 VBB31736.1 - 1.3 8.8 12.2 3.2 7.6 12.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 VBB31736.1 - 3.4 7.4 7.1 6.4 6.5 7.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger RRM_1 PF00076.22 VBB31737.1 - 1.2e-11 44.2 0.3 2.5e-11 43.2 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHS_repeat PF05593.14 VBB31737.1 - 0.44 11.1 2.6 0.35 11.4 0.5 1.9 2 0 0 2 2 2 0 RHS Repeat BTB PF00651.31 VBB31738.1 - 1.1e-05 25.7 0.0 0.054 13.7 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain ABC_tran PF00005.27 VBB31739.1 - 3.3e-43 147.5 4.7 1.1e-20 74.5 0.0 3.5 3 1 1 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 VBB31739.1 - 6.8e-24 83.7 4.7 6.8e-24 83.7 4.7 2.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 VBB31739.1 - 6.8e-20 72.1 9.0 1.1e-05 25.5 0.2 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 VBB31739.1 - 1.1e-10 41.3 1.9 0.0064 16.0 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 VBB31739.1 - 2.4e-07 30.8 0.1 0.0052 16.8 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 VBB31739.1 - 7.4e-06 25.9 13.3 0.016 14.9 3.4 3.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 VBB31739.1 - 9.7e-06 25.4 0.1 0.13 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 VBB31739.1 - 1.5e-05 25.3 1.7 0.067 13.5 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.6 VBB31739.1 - 2.9e-05 23.7 0.7 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 VBB31739.1 - 6.2e-05 23.0 0.1 0.07 13.0 0.0 2.9 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 VBB31739.1 - 8e-05 22.6 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 VBB31739.1 - 0.00019 21.8 0.2 0.022 15.1 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 VBB31739.1 - 0.00047 20.7 1.2 0.46 11.0 0.0 3.4 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 VBB31739.1 - 0.00054 20.1 5.3 0.15 12.1 0.0 3.5 4 0 0 4 4 3 2 Dynamin family Arf PF00025.21 VBB31739.1 - 0.0012 18.3 0.1 0.22 11.0 0.0 2.9 3 0 0 3 3 2 1 ADP-ribosylation factor family AAA_14 PF13173.6 VBB31739.1 - 0.0015 18.6 0.2 1.6 8.8 0.1 3.7 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 VBB31739.1 - 0.0015 18.9 0.0 0.95 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MobB PF03205.14 VBB31739.1 - 0.0021 18.0 0.1 0.053 13.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 VBB31739.1 - 0.0023 17.9 0.1 0.63 10.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 VBB31739.1 - 0.0025 18.0 2.2 5.7 7.1 0.0 3.7 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 VBB31739.1 - 0.0046 16.2 0.2 2.1 7.5 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 VBB31739.1 - 0.0056 16.9 1.7 0.44 10.8 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 VBB31739.1 - 0.0063 16.9 0.0 1.3 9.4 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 VBB31739.1 - 0.0064 17.0 0.0 0.0064 17.0 0.0 4.7 4 1 0 4 4 3 2 AAA domain cobW PF02492.19 VBB31739.1 - 0.0065 16.1 0.2 1.2 8.7 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 VBB31739.1 - 0.0077 16.0 0.0 6.2 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 VBB31739.1 - 0.0085 16.0 0.2 2.2 8.2 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_7 PF12775.7 VBB31739.1 - 0.011 15.3 0.8 4.6 6.7 0.0 2.9 2 1 1 3 3 3 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 VBB31739.1 - 0.026 13.8 0.6 2.7 7.2 0.0 2.8 2 1 0 2 2 2 0 Zeta toxin Septin PF00735.18 VBB31739.1 - 0.036 13.4 2.7 3.9 6.7 0.0 2.7 3 0 0 3 3 2 0 Septin AAA_28 PF13521.6 VBB31739.1 - 0.043 14.1 0.6 1.1 9.5 0.0 3.0 3 1 0 3 3 2 0 AAA domain dNK PF01712.19 VBB31739.1 - 0.051 13.4 1.9 2.2 8.1 0.0 3.2 3 0 0 3 3 3 0 Deoxynucleoside kinase Pox_A32 PF04665.12 VBB31739.1 - 0.073 12.5 1.0 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_27 PF13514.6 VBB31739.1 - 0.091 12.3 6.7 0.6 9.7 0.1 3.1 4 0 0 4 4 3 0 AAA domain PhetRS_B1 PF18262.1 VBB31739.1 - 0.11 12.7 0.1 4.9 7.4 0.0 3.3 3 0 0 3 3 2 0 Phe-tRNA synthetase beta subunit B1 domain AAA_5 PF07728.14 VBB31739.1 - 0.12 12.4 0.9 7.2 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 VBB31739.1 - 0.19 11.5 2.9 3.2 7.5 0.1 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 VBB31739.1 - 0.43 10.7 15.9 1.7 8.7 0.0 4.9 5 2 2 7 7 6 0 Helicase HerA, central domain Glyco_hydro_56 PF01630.18 VBB31739.1 - 0.49 9.4 2.8 19 4.1 0.0 2.3 2 0 0 2 2 2 0 Hyaluronidase YolD PF08863.10 VBB31739.1 - 1.1 9.3 7.2 1.6 8.8 0.0 3.2 3 0 0 3 3 2 0 YolD-like protein AAA_17 PF13207.6 VBB31739.1 - 1.3 9.4 5.9 2.1 8.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain Colicin-DNase PF12639.7 VBB31739.1 - 8.8 7.2 7.5 0.99 10.3 1.2 2.5 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Zona_pellucida PF00100.23 VBB31741.1 - 9.2e-13 48.6 1.9 1.3e-12 48.1 1.9 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain CoA_binding_3 PF13727.6 VBB31741.1 - 0.13 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 CoA-binding domain 60KD_IMP PF02096.20 VBB31742.1 - 6.6e-10 39.1 0.3 9.2e-10 38.7 0.3 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2418 PF10332.9 VBB31742.1 - 0.091 13.3 1.6 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) 60KD_IMP PF02096.20 VBB31743.1 - 1.3e-16 61.0 5.1 1.8e-16 60.5 5.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein TcA_TcB_BD PF18276.1 VBB31743.1 - 0.16 11.0 0.6 0.27 10.3 0.6 1.3 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain 60KD_IMP PF02096.20 VBB31744.1 - 1.7e-05 24.8 4.0 1.7e-05 24.8 4.0 2.2 1 1 1 2 2 2 1 60Kd inner membrane protein RNA_pol_Rpb1_5 PF04998.17 VBB31744.1 - 0.062 12.7 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 RNB PF00773.19 VBB31744.1 - 0.075 12.3 0.2 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 RNB domain RNA_pol_Rpb4 PF03874.16 VBB31745.1 - 0.00074 19.9 0.1 0.00082 19.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 LPD13 PF18825.1 VBB31745.1 - 0.061 13.1 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 ADH_zinc_N PF00107.26 VBB31746.1 - 1.3e-15 57.6 0.0 3.4e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 VBB31746.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 VBB31746.1 - 6.8e-10 40.1 0.0 1.4e-09 39.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_18 PF13746.6 VBB31746.1 - 0.045 13.9 1.0 0.082 13.1 1.0 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain APG9 PF04109.16 VBB31747.1 - 1.5e-125 419.9 0.1 2e-125 419.5 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RRP36 PF06102.12 VBB31748.1 - 8.8e-36 123.4 19.3 8.8e-36 123.4 19.3 2.0 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 CCDC74_C PF14917.6 VBB31748.1 - 0.045 14.3 5.9 0.25 11.9 1.1 2.8 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal CRAL_TRIO PF00650.20 VBB31749.1 - 2.3e-12 46.9 0.2 3.6e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GIY-YIG PF01541.24 VBB31750.1 - 7.6e-15 55.0 0.4 1.7e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-RING_2 PF13639.6 VBB31750.1 - 0.011 16.0 5.6 0.011 16.0 5.6 2.1 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.22 VBB31750.1 - 0.012 15.5 1.4 0.033 14.1 1.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 VBB31750.1 - 0.014 15.3 3.4 0.045 13.6 3.4 1.9 1 0 0 1 1 1 0 PHD-finger T5orf172 PF10544.9 VBB31750.1 - 0.029 14.9 0.0 0.075 13.6 0.0 1.8 1 0 0 1 1 1 0 T5orf172 domain FANCL_C PF11793.8 VBB31750.1 - 0.032 14.4 4.6 0.35 11.1 4.6 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 VBB31750.1 - 0.046 13.9 1.5 0.13 12.4 1.5 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 VBB31750.1 - 0.12 12.6 5.1 0.044 14.0 1.7 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Nckap1 PF09735.9 VBB31751.1 - 0 1386.7 33.7 0 1386.4 33.7 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein ICAP-1_inte_bdg PF10480.9 VBB31751.1 - 1.4e-08 35.0 0.2 2.8e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 VBB31751.1 - 0.0068 16.5 0.0 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HLH PF00010.26 VBB31752.1 - 8.8e-16 57.6 1.2 2.2e-15 56.3 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 VBB31752.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain Rrp15p PF07890.12 VBB31752.1 - 1.4 9.2 13.0 0.63 10.4 3.9 2.5 2 0 0 2 2 2 0 Rrp15p BBS2_Mid PF14783.6 VBB31753.1 - 0.00094 19.2 0.0 0.0033 17.4 0.0 1.9 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region LemA PF04011.12 VBB31753.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 LemA family CLIP PF12032.8 VBB31753.1 - 0.041 14.2 3.2 0.17 12.2 0.1 3.1 3 0 0 3 3 3 0 Regulatory CLIP domain of proteinases DUF349 PF03993.12 VBB31753.1 - 0.13 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) AlkA_N PF06029.11 VBB31753.1 - 0.36 11.1 1.8 0.54 10.6 0.5 1.9 2 0 0 2 2 2 0 AlkA N-terminal domain THOC7 PF05615.13 VBB31753.1 - 4 7.7 5.5 3.2 8.0 0.8 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 PDZ PF00595.24 VBB31754.1 - 0.00015 22.0 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB31754.1 - 0.024 14.5 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 PDZ domain Aminotran_1_2 PF00155.21 VBB31755.1 - 4.5e-73 246.5 0.0 6.8e-73 245.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Adap_comp_sub PF00928.21 VBB31757.1 - 4e-72 242.7 0.0 5.4e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 VBB31757.1 - 0.0063 16.5 0.4 0.012 15.5 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mito_carr PF00153.27 VBB31758.1 - 6.1e-11 42.1 0.0 2.2e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein IFT57 PF10498.9 VBB31759.1 - 2.7e-109 365.5 14.5 3.4e-109 365.2 14.5 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ZapA PF05164.13 VBB31759.1 - 0.0011 19.3 1.3 0.0055 17.1 1.3 2.2 1 1 0 1 1 1 1 Cell division protein ZapA Lectin_legB PF00139.19 VBB31759.1 - 0.01 15.4 0.8 0.018 14.6 0.8 1.3 1 0 0 1 1 1 0 Legume lectin domain DUF1664 PF07889.12 VBB31759.1 - 0.011 15.7 2.4 0.011 15.7 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_23 PF13476.6 VBB31759.1 - 0.012 16.1 8.7 0.012 16.1 8.7 2.2 2 1 0 2 2 1 0 AAA domain Spc7 PF08317.11 VBB31759.1 - 0.016 14.1 13.5 0.048 12.5 12.8 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 VBB31759.1 - 0.059 13.3 5.9 0.14 12.0 5.8 1.8 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein TPR_MLP1_2 PF07926.12 VBB31759.1 - 0.075 13.1 11.5 0.051 13.6 8.1 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ApoO PF09769.9 VBB31759.1 - 0.13 12.2 0.4 0.82 9.6 0.4 2.2 1 1 0 1 1 1 0 Apolipoprotein O DNA_repr_REX1B PF14966.6 VBB31759.1 - 0.15 12.7 6.0 0.15 12.7 2.4 2.6 1 1 2 3 3 3 0 DNA repair REX1-B DUF1027 PF06265.11 VBB31759.1 - 0.2 11.7 1.4 0.7 9.9 1.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) ABC_tran_CTD PF16326.5 VBB31759.1 - 0.3 11.4 7.9 7.5 6.9 1.6 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain TMPIT PF07851.13 VBB31759.1 - 0.34 10.1 10.8 0.64 9.2 6.8 2.2 1 1 1 2 2 2 0 TMPIT-like protein KxDL PF10241.9 VBB31759.1 - 0.37 11.1 8.9 1.7 9.0 2.0 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF724 PF05266.14 VBB31759.1 - 0.45 10.3 13.0 0.38 10.5 11.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 VBB31759.1 - 0.5 10.4 12.6 0.17 11.9 5.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 VBB31759.1 - 0.71 9.9 7.4 0.4 10.7 3.7 2.4 1 1 0 2 2 2 0 Laminin Domain II FAP206 PF12018.8 VBB31759.1 - 1.1 8.6 9.1 2.2 7.7 0.1 3.0 1 1 1 3 3 3 0 Domain of unknown function Exonuc_VII_L PF02601.15 VBB31759.1 - 1.7 8.1 10.8 4.7 6.7 10.8 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 VBB31759.1 - 2.7 7.0 12.3 4.7 6.2 12.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 VBB31759.1 - 3.5 8.0 9.8 0.53 10.6 1.4 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.13 VBB31759.1 - 3.5 7.7 17.0 0.13 12.4 9.2 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IZUMO PF15005.6 VBB31759.1 - 6.8 7.2 8.2 2.7 8.5 0.8 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated MADF_DNA_bdg PF10545.9 VBB31760.1 - 4.7e-13 49.2 2.2 9.7e-13 48.3 2.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 VBB31760.1 - 2e-09 37.4 4.3 5.4e-09 36.0 4.3 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 VBB31760.1 - 0.00011 22.5 3.7 0.00024 21.4 3.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PP2C_C PF07830.13 VBB31761.1 - 0.18 12.3 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain LIM PF00412.22 VBB31762.1 - 2e-24 85.6 41.0 3.6e-10 39.9 10.1 3.7 3 0 0 3 3 3 3 LIM domain PDZ_6 PF17820.1 VBB31762.1 - 1.5e-05 24.7 0.1 4.2e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 VBB31762.1 - 9.7e-05 23.4 1.4 9.7e-05 23.4 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) adh_short PF00106.25 VBB31763.1 - 4.2e-47 160.1 0.7 6.3e-47 159.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB31763.1 - 2.9e-30 105.6 0.1 3.8e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB31763.1 - 1.5e-06 28.3 0.3 2.3e-06 27.6 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF745 PF05335.13 VBB31763.1 - 0.0093 15.7 0.3 0.013 15.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) 3HCDH_N PF02737.18 VBB31763.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 VBB31763.1 - 0.16 11.8 0.4 0.34 10.8 0.4 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Zona_pellucida PF00100.23 VBB31764.1 - 1.9e-12 47.5 5.3 2.5e-12 47.1 5.3 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain BAH PF01426.18 VBB31767.1 - 1.2e-06 28.3 0.1 7.7e-06 25.8 0.1 2.0 1 1 0 1 1 1 1 BAH domain Reticulon PF02453.17 VBB31768.1 - 5.4e-41 140.2 7.9 9.8e-41 139.3 1.7 2.1 2 0 0 2 2 2 2 Reticulon EI24 PF07264.11 VBB31768.1 - 0.013 15.8 6.7 0.59 10.4 0.8 2.2 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF639 PF04842.12 VBB31768.1 - 0.098 12.1 0.8 0.17 11.3 0.4 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF2547 PF10818.8 VBB31768.1 - 0.16 12.9 0.1 0.45 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) ApoLp-III PF07464.11 VBB31770.1 - 0.0056 16.8 3.4 2.3 8.3 0.3 3.3 2 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 VBB31770.1 - 0.035 14.0 1.5 0.9 9.4 1.5 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Senescence PF06911.12 VBB31770.1 - 0.25 11.7 3.1 1.8 8.8 3.1 2.3 1 1 0 1 1 1 0 Senescence-associated protein Laminin_I PF06008.14 VBB31770.1 - 0.36 10.5 4.7 30 4.2 2.7 3.1 2 1 1 3 3 3 0 Laminin Domain I Chlorosome_CsmC PF11098.8 VBB31770.1 - 0.43 10.6 5.5 1.5 8.8 2.7 3.2 2 1 1 3 3 3 0 Chlorosome envelope protein C DUF2884 PF11101.8 VBB31770.1 - 2.2 7.7 5.2 4.7 6.6 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF883 PF05957.13 VBB31770.1 - 3.6 8.3 6.9 19 6.0 0.4 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 VBB31770.1 - 3.7 8.1 13.0 4.5e+02 1.5 9.5 4.0 2 1 0 2 2 2 0 YtxH-like protein DUF948 PF06103.11 VBB31770.1 - 5.1 7.4 8.9 11 6.4 0.3 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) RNA_replicase_B PF03431.13 VBB31771.1 - 0.074 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA replicase, beta-chain Izumo-Ig PF16706.5 VBB31771.1 - 0.083 13.0 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Big_2 PF02368.18 VBB31772.1 - 1.2e-08 34.7 0.7 0.23 11.4 0.0 6.2 6 0 0 6 6 6 4 Bacterial Ig-like domain (group 2) Acyl_transf_3 PF01757.22 VBB31774.1 - 1.6e-15 57.0 48.5 1.6e-15 57.0 48.5 1.7 2 0 0 2 2 2 1 Acyltransferase family SH3_9 PF14604.6 VBB31775.1 - 0.004 17.0 0.1 0.0068 16.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB31775.1 - 0.007 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB31775.1 - 0.017 14.7 0.3 0.03 13.9 0.3 1.3 1 0 0 1 1 1 0 SH3 domain ArfGap PF01412.18 VBB31776.1 - 1.8e-31 108.6 1.9 4e-31 107.5 1.9 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3546 PF12066.8 VBB31776.1 - 0.12 12.5 4.7 0.039 14.1 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) WASH-7_mid PF14744.6 VBB31777.1 - 6.1e-126 420.2 5.7 6.1e-126 420.2 5.7 1.8 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_N PF14745.6 VBB31777.1 - 4.1e-84 283.1 19.7 5.6e-84 282.7 19.7 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 VBB31777.1 - 2.7e-39 134.7 0.9 5.3e-39 133.7 0.1 2.0 2 0 0 2 2 2 1 WASH complex subunit 7, C-terminal FliS PF02561.14 VBB31777.1 - 0.25 11.6 2.8 11 6.3 0.0 3.6 3 1 0 3 3 3 0 Flagellar protein FliS DUF2919 PF11143.8 VBB31777.1 - 1.2 9.5 6.1 5.8 7.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) PXA PF02194.15 VBB31777.1 - 5.1 7.0 7.0 0.88 9.5 0.2 3.1 4 1 0 4 4 4 0 PXA domain AA_permease PF00324.21 VBB31778.1 - 1.3e-37 129.5 41.6 1.3e-37 129.5 41.6 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 VBB31778.1 - 3.4e-12 45.9 42.1 3.4e-12 45.9 42.1 2.2 1 1 1 2 2 2 1 Amino acid permease CAMSAP_CKK PF08683.11 VBB31779.1 - 1.5e-40 138.0 0.0 3.5e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 VBB31779.1 - 6.8e-26 89.9 0.3 1.7e-25 88.6 0.3 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 VBB31779.1 - 0.0038 17.4 0.0 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain DEAD PF00270.29 VBB31780.1 - 2.5e-24 86.0 0.0 5.4e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31780.1 - 4.6e-22 78.5 0.1 2.9e-21 75.9 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB31780.1 - 9.9e-09 35.4 0.1 4.1e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 VBB31780.1 - 0.0016 18.7 0.0 0.0053 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain C-C_Bond_Lyase PF15617.6 VBB31780.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold AAA_23 PF13476.6 VBB31780.1 - 0.36 11.3 4.8 13 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain NOC3p PF07540.11 VBB31781.1 - 5.6e-23 81.2 0.4 5.6e-23 81.2 0.4 2.7 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 VBB31781.1 - 5.2e-10 39.6 1.8 3.6e-09 36.9 0.0 2.8 3 0 0 3 3 3 1 CBF/Mak21 family KIND PF16474.5 VBB31781.1 - 1 9.2 6.3 0.071 13.0 0.5 2.0 3 0 0 3 3 3 0 Kinase non-catalytic C-lobe domain ATPase PF06745.13 VBB31781.1 - 2.8 7.2 5.1 0.65 9.3 0.8 2.0 2 0 0 2 2 2 0 KaiC Ground-like PF04155.18 VBB31782.1 - 1.4e-23 83.3 2.8 1.4e-23 83.3 2.8 2.4 3 0 0 3 3 3 1 Ground-like domain CIMR PF00878.18 VBB31782.1 - 0.037 14.1 0.4 0.037 14.1 0.4 1.6 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat DUF3398 PF11878.8 VBB31782.1 - 0.088 13.2 0.1 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) DUF5301 PF17225.3 VBB31782.1 - 0.42 11.1 3.8 0.29 11.6 1.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) XPG_I PF00867.18 VBB31783.1 - 4.2e-25 87.9 0.2 2.9e-24 85.2 0.0 2.6 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.17 VBB31783.1 - 2.8e-22 79.1 0.0 7.3e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain DUF5301 PF17225.3 VBB31783.1 - 2.3 8.7 6.4 0.92 10.0 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) ATP-synt_E PF05680.12 VBB31783.1 - 8.6 6.8 7.0 28 5.2 3.8 2.7 2 0 0 2 2 2 0 ATP synthase E chain RRM_1 PF00076.22 VBB31784.1 - 7.8e-10 38.4 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) I-set PF07679.16 VBB31785.1 - 3.8e-36 123.0 0.0 9.3e-12 44.9 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB31785.1 - 1e-33 115.8 0.1 2.4e-10 40.9 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB31785.1 - 9.8e-26 89.8 0.0 3e-08 33.7 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB31785.1 - 4.4e-25 87.8 0.2 2.3e-08 34.3 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 VBB31785.1 - 2.6e-17 63.0 0.0 3.6e-05 23.9 0.0 4.5 3 1 1 4 4 4 2 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB31785.1 - 2.9e-07 30.8 0.0 0.29 11.6 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 VBB31785.1 - 2.5e-05 24.5 0.1 0.61 10.4 0.0 4.0 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 VBB31785.1 - 6.3e-05 22.5 0.0 3.5 7.3 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 VBB31785.1 - 7.7e-05 22.7 0.0 0.041 14.0 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 VBB31785.1 - 0.00023 21.2 0.0 1.6 8.8 0.0 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 VBB31785.1 - 0.00058 20.0 0.0 0.4 10.9 0.0 3.2 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 DNA_pol_B PF00136.21 VBB31786.1 - 4.1e-138 460.9 0.4 5.1e-117 391.4 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 VBB31786.1 - 4.2e-71 239.8 1.1 8.2e-71 238.9 1.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 VBB31786.1 - 1.3e-09 38.4 4.6 3.6e-09 36.9 4.6 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 VBB31786.1 - 0.0013 17.7 0.1 0.0022 16.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 VBB31786.1 - 0.075 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 3'-5' exonuclease TUG-UBL1 PF11470.8 VBB31786.1 - 0.13 12.5 0.5 23 5.3 0.0 2.9 3 0 0 3 3 3 0 TUG ubiquitin-like domain AMP-binding PF00501.28 VBB31787.1 - 3.9e-43 147.6 0.0 5.3e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BAR_3 PF16746.5 VBB31788.1 - 1.7e-65 221.1 13.4 2.4e-65 220.6 13.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 VBB31788.1 - 1.7e-06 28.5 1.9 4.7e-06 27.0 0.1 2.6 2 1 1 3 3 3 1 PH domain BAR PF03114.18 VBB31788.1 - 1.7e-05 24.6 4.9 1.7e-05 24.6 4.9 2.2 1 1 1 2 2 2 1 BAR domain Vps5 PF09325.10 VBB31788.1 - 0.0018 17.9 6.6 0.0025 17.4 2.0 2.6 2 1 0 2 2 2 1 Vps5 C terminal like Arfaptin PF06456.13 VBB31788.1 - 0.027 14.0 0.9 0.027 14.0 0.9 2.5 1 1 0 2 2 2 0 Arfaptin-like domain PH_9 PF15410.6 VBB31788.1 - 0.46 10.9 5.4 11 6.5 2.4 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Fib_alpha PF08702.10 VBB31788.1 - 6.6 6.9 8.1 9.6 6.4 0.5 3.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family RhoGAP PF00620.27 VBB31789.1 - 5.7e-42 143.1 0.1 9.2e-42 142.4 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain Cullin PF00888.22 VBB31790.1 - 1.7e-207 690.9 8.5 2e-207 690.6 8.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 VBB31790.1 - 5.1e-27 93.7 2.0 1.5e-26 92.2 2.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain NusB PF01029.18 VBB31790.1 - 0.0046 17.2 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 NusB family WAC_Acf1_DNA_bd PF10537.9 VBB31790.1 - 0.82 10.2 3.6 0.94 10.0 0.1 2.9 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal Ank_4 PF13637.6 VBB31791.1 - 5.9e-11 42.7 0.0 4e-07 30.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB31791.1 - 6.9e-06 26.2 0.0 3.1e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 VBB31791.1 - 2.2e-05 24.7 0.4 0.0001 22.6 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 VBB31791.1 - 4.6e-05 23.9 0.0 5.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB31791.1 - 6.3e-05 23.1 0.2 0.078 13.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat RCC1 PF00415.18 VBB31792.1 - 2.3e-41 140.2 3.0 1.7e-07 31.7 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB31792.1 - 6.4e-29 99.1 26.1 1.1e-07 31.4 0.0 7.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 VBB31792.1 - 0.032 14.5 0.3 32 4.9 0.1 4.0 4 0 0 4 4 4 0 Putative heavy-metal chelation UBA_4 PF14555.6 VBB31793.1 - 1.4e-06 28.0 0.7 3.5e-06 26.7 0.7 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 VBB31793.1 - 1.9e-05 24.7 0.0 5.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 UBX domain AAA_23 PF13476.6 VBB31793.1 - 0.38 11.2 9.0 0.76 10.2 9.0 1.5 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.9 VBB31793.1 - 4.7 6.8 24.2 8.6 5.9 24.2 1.4 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 VBB31793.1 - 6 6.6 11.3 12 5.6 11.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Alg14 PF08660.11 VBB31794.1 - 5.6 6.9 8.3 2 8.3 3.6 2.1 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like DNA_pol_A_exo1 PF01612.20 VBB31796.1 - 3.7e-37 127.7 0.7 9.2e-37 126.4 0.7 1.7 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 VBB31796.1 - 1.1e-13 51.7 0.1 1.3e-12 48.2 0.0 2.8 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 VBB31796.1 - 8.4e-12 44.9 1.8 1.6e-11 44.0 0.0 2.4 3 0 0 3 3 3 1 HRDC domain FapA PF03961.13 VBB31796.1 - 0.92 8.0 10.0 1.4 7.5 10.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 VBB31796.1 - 2.1 7.2 3.8 3.6 6.4 3.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein PHTB1_N PF14727.6 VBB31797.1 - 2.1e-49 169.0 0.1 2.3e-49 168.9 0.1 1.0 1 0 0 1 1 1 1 PTHB1 N-terminus DUF2615 PF11027.8 VBB31798.1 - 0.01 15.9 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) UPF0542 PF15086.6 VBB31798.1 - 0.044 13.7 0.5 0.057 13.4 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 HemY_N PF07219.13 VBB31798.1 - 0.05 13.8 0.1 0.066 13.4 0.1 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Wzy_C_2 PF11846.8 VBB31798.1 - 0.12 12.2 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Presenilin PF01080.17 VBB31798.1 - 0.51 9.0 4.1 0.11 11.3 1.0 1.4 1 1 0 1 1 1 0 Presenilin 3HCDH_N PF02737.18 VBB31799.1 - 5e-55 186.2 0.2 8.3e-55 185.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 VBB31799.1 - 1.1e-36 126.5 0.1 1.5e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 VBB31799.1 - 2.7e-24 86.3 0.2 7.4e-24 84.9 0.1 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 VBB31799.1 - 5.7e-24 84.6 0.0 3.4e-17 62.8 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 VBB31799.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4588 PF15251.6 VBB31800.1 - 1.7e-08 34.5 1.7 2.1e-08 34.2 0.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) HIGH_NTase1 PF05636.11 VBB31801.1 - 0.024 13.9 2.9 0.03 13.5 2.9 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase BLOC1_2 PF10046.9 VBB31801.1 - 1.2 9.5 4.7 1.3 9.4 1.3 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 VBB31802.1 - 2.1 8.3 5.5 2.2 8.2 0.1 3.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BRO1 PF03097.18 VBB31803.1 - 2.4e-26 92.5 0.0 3e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF236 PF03057.14 VBB31804.1 - 1.1e-77 255.6 27.1 2.2e-16 59.5 0.7 5.3 5 0 0 5 5 5 5 DUF236 repeat Acetyltransf_1 PF00583.25 VBB31805.1 - 2.7e-15 56.6 0.0 4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 VBB31805.1 - 1.3e-09 38.4 0.0 2.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 VBB31805.1 - 1.5e-09 37.9 0.1 2.2e-09 37.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 VBB31805.1 - 4.3e-06 26.6 0.0 6.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 VBB31805.1 - 0.0016 17.9 0.6 0.0049 16.4 0.6 1.8 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 VBB31805.1 - 0.0066 17.1 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 VBB31805.1 - 0.021 14.8 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 VBB31805.1 - 0.022 14.8 0.1 0.039 14.0 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Med14 PF08638.11 VBB31806.1 - 1.9e-44 151.4 0.2 5.5e-44 149.9 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 Cg6151-P PF10233.9 VBB31807.1 - 1.5e-28 99.3 10.6 2e-28 99.0 10.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 VBB31807.1 - 0.002 17.8 0.7 0.0028 17.4 0.7 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 TMEM43 PF07787.12 VBB31807.1 - 0.093 12.1 0.7 0.13 11.6 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 EI24 PF07264.11 VBB31807.1 - 0.17 12.1 7.5 0.21 11.8 7.5 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.9 VBB31807.1 - 6.6 5.4 5.0 4.2 6.0 3.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Amidinotransf PF02274.17 VBB31808.1 - 0.0022 17.1 0.0 1.7 7.6 0.0 2.3 1 1 1 2 2 2 2 Amidinotransferase Sigma70_r1_1 PF03979.14 VBB31808.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 KKLCAg1 PF15204.6 VBB31808.1 - 0.028 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Homeodomain PF00046.29 VBB31809.1 - 4.1e-21 74.6 4.1 6.6e-21 73.9 4.1 1.3 1 0 0 1 1 1 1 Homeodomain DUF4638 PF15472.6 VBB31809.1 - 0.044 13.5 0.2 0.072 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RNA_polI_A34 PF08208.11 VBB31810.1 - 0.024 14.7 17.1 0.033 14.3 17.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 OFeT_1 PF16955.5 VBB31810.1 - 0.097 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF3894 PF13033.6 VBB31810.1 - 0.098 12.8 1.7 0.16 12.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Neur_chan_memb PF02932.16 VBB31810.1 - 0.13 12.3 0.6 0.17 11.9 0.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med19 PF10278.9 VBB31810.1 - 0.28 11.1 13.3 1.1 9.2 14.1 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 ALC PF17527.2 VBB31810.1 - 0.33 10.6 7.9 0.59 9.8 7.9 1.3 1 0 0 1 1 1 0 Phage ALC protein AP3D1 PF06375.11 VBB31810.1 - 1 9.6 17.1 1.9 8.7 17.1 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 EOS1 PF12326.8 VBB31810.1 - 2.5 8.0 4.2 3.6 7.5 4.2 1.3 1 1 0 1 1 1 0 N-glycosylation protein DUF1129 PF06570.11 VBB31810.1 - 3.3 7.2 6.4 0.34 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sulfate_transp PF00916.20 VBB31811.1 - 1.2e-90 304.1 23.1 2.3e-90 303.1 23.1 1.5 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 VBB31811.1 - 2.5e-18 65.8 0.0 4.2e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 VBB31811.1 - 2.2 8.7 17.3 0.12 12.8 6.0 3.5 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily zf-HC5HC2H_2 PF13832.6 VBB31812.1 - 4.9e-28 97.5 7.2 4.9e-28 97.5 7.2 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 VBB31812.1 - 1.5e-20 73.2 18.2 4.9e-20 71.6 7.1 3.2 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 VBB31812.1 - 1.5e-12 46.8 4.3 1.5e-12 46.8 4.3 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 VBB31812.1 - 1.3e-07 31.4 9.6 1.3e-07 31.4 9.6 3.1 2 0 0 2 2 2 1 PHD-finger zf-C4 PF00105.18 VBB31814.1 - 3.1e-28 98.0 12.3 6.7e-28 96.9 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GOLD_2 PF13897.6 VBB31815.1 - 1.7e-69 232.6 2.7 1.7e-69 232.6 2.7 2.0 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking DUF4598 PF15370.6 VBB31815.1 - 0.022 15.2 1.4 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) F-box PF00646.33 VBB31816.1 - 8.5e-05 22.3 0.1 0.00027 20.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 VBB31816.1 - 0.00023 21.5 26.3 0.45 11.0 0.0 8.5 5 3 5 10 10 10 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB31816.1 - 0.00043 20.1 7.3 0.37 11.0 0.2 5.8 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.7 VBB31816.1 - 0.004 17.0 0.2 0.004 17.0 0.2 2.5 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 VBB31816.1 - 0.037 13.8 14.4 6.6 6.6 0.2 7.0 6 1 2 8 8 8 0 Leucine rich repeat zf-FPG_IleRS PF06827.14 VBB31816.1 - 0.16 11.8 0.3 0.48 10.3 0.3 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Selenoprotein_S PF06936.11 VBB31817.1 - 0.088 12.6 4.4 0.1 12.4 4.4 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) G0-G1_switch_2 PF15103.6 VBB31817.1 - 0.09 13.2 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DDOST_48kD PF03345.14 VBB31818.1 - 3.4e-146 487.3 1.5 4.3e-146 487.0 0.1 1.9 2 0 0 2 2 2 1 Oligosaccharyltransferase 48 kDa subunit beta zf-C3H1 PF10650.9 VBB31818.1 - 0.00026 20.6 0.3 0.00053 19.6 0.3 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain cNMP_binding PF00027.29 VBB31819.1 - 1.2e-30 105.5 0.7 1.6e-17 63.3 0.0 3.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 VBB31819.1 - 3.3e-11 42.6 0.1 6.1e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 VBB31819.1 - 0.00035 20.2 0.9 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 Cupin domain DUF5586 PF17824.1 VBB31819.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5586) RA PF00788.23 VBB31820.1 - 1.7e-06 28.6 0.0 4e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain MADF_DNA_bdg PF10545.9 VBB31821.1 - 6.1e-17 61.7 3.3 6.1e-17 61.7 3.3 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB31821.1 - 2.2e-07 31.2 2.4 2.2e-07 31.2 2.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 VBB31821.1 - 0.0056 16.7 0.5 0.015 15.3 0.5 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Proteasom_PSMB PF10508.9 VBB31822.1 - 8.3e-80 268.7 2.5 9.9e-80 268.4 2.5 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 VBB31822.1 - 0.0011 17.6 0.2 0.0022 16.6 0.2 1.6 1 0 0 1 1 1 1 Adaptin N terminal region ERAP1_C PF11838.8 VBB31822.1 - 0.098 12.2 0.0 2.3 7.7 0.0 2.3 2 1 0 2 2 2 0 ERAP1-like C-terminal domain OTU PF02338.19 VBB31824.1 - 2.7e-15 57.0 0.0 6.9e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Yippee-Mis18 PF03226.14 VBB31824.1 - 5.4e-11 42.6 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Peptidase_C65 PF10275.9 VBB31824.1 - 2.9e-06 26.9 0.4 0.01 15.3 0.1 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain RIG-I_C-RD PF11648.8 VBB31824.1 - 0.0048 17.1 0.2 0.014 15.6 0.2 1.7 1 0 0 1 1 1 1 C-terminal domain of RIG-I UIM PF02809.20 VBB31824.1 - 0.035 14.0 1.1 0.16 12.0 1.1 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif CSTF_C PF14304.6 VBB31824.1 - 0.07 12.7 0.7 0.16 11.6 0.7 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Beta_helix PF13229.6 VBB31825.1 - 3.6e-69 231.6 41.4 1e-26 93.7 6.8 4.7 2 1 3 5 5 5 3 Right handed beta helix region NosD PF05048.13 VBB31825.1 - 3.1e-40 138.0 17.6 1.3e-17 63.9 2.1 4.6 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) zf-C2HC PF01530.18 VBB31825.1 - 8.8e-13 48.2 6.1 2.2e-12 46.9 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2HC type F-box-like PF12937.7 VBB31825.1 - 1.5e-09 37.6 0.4 4.9e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 VBB31825.1 - 2.7e-06 27.1 0.2 2.7e-06 27.1 0.2 2.7 3 0 0 3 3 3 1 F-box domain zf-UBR PF02207.20 VBB31825.1 - 5.8e-05 23.2 7.8 0.00021 21.4 7.8 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Lebercilin PF15619.6 VBB31826.1 - 0.00036 20.2 10.8 0.00073 19.2 10.8 1.5 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 VBB31826.1 - 0.0014 18.7 8.8 0.0014 18.7 8.8 1.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CdvA PF18822.1 VBB31826.1 - 0.0021 17.9 5.7 0.0021 17.9 5.7 2.1 2 0 0 2 2 2 1 CdvA-like coiled-coil domain BAR PF03114.18 VBB31826.1 - 0.0027 17.4 5.9 0.23 11.0 3.8 2.1 1 1 1 2 2 2 2 BAR domain PspA_IM30 PF04012.12 VBB31826.1 - 0.0099 15.5 5.6 0.0099 15.5 5.6 1.8 1 1 1 2 2 2 1 PspA/IM30 family Filament PF00038.21 VBB31826.1 - 0.011 15.4 11.2 0.015 14.9 11.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein Laminin_II PF06009.12 VBB31826.1 - 0.076 13.0 3.3 0.073 13.1 1.6 1.9 1 1 0 1 1 1 0 Laminin Domain II ERM PF00769.19 VBB31826.1 - 0.1 12.4 12.6 0.2 11.4 12.8 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.9 VBB31826.1 - 0.1 11.7 6.9 0.12 11.5 6.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 VBB31826.1 - 0.15 12.2 3.7 0.2 11.8 2.4 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 VBB31826.1 - 0.2 11.9 8.6 0.38 11.0 7.7 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 VBB31826.1 - 0.31 11.1 12.6 0.055 13.6 8.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 VBB31826.1 - 0.33 10.5 3.5 0.34 10.4 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 VBB31826.1 - 0.36 11.5 5.3 0.48 11.1 4.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Mod_r PF07200.13 VBB31826.1 - 0.42 10.7 9.3 0.23 11.6 6.3 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 VBB31826.1 - 0.53 10.8 13.6 0.17 12.4 10.4 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 VBB31826.1 - 0.89 9.8 6.0 0.73 10.1 4.0 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 VBB31826.1 - 1.7 7.9 7.5 0.89 8.8 4.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 VBB31826.1 - 2.5 8.6 8.8 11 6.5 8.8 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 MIP-T3_C PF17749.1 VBB31826.1 - 3.1 7.8 10.9 1.6 8.7 0.4 3.0 1 1 3 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region HIP1_clath_bdg PF16515.5 VBB31826.1 - 3.7 8.2 12.0 5.5 7.7 4.6 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 VBB31826.1 - 5 7.4 14.4 19 5.5 14.4 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 DUF4446 PF14584.6 VBB31826.1 - 6.1 6.8 9.3 4 7.4 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF724 PF05266.14 VBB31826.1 - 8.4 6.2 12.1 1.4 8.7 6.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 VBB31826.1 - 10 5.3 10.1 28 3.8 10.7 1.5 1 1 1 2 2 2 0 TMPIT-like protein DDT PF02791.17 VBB31827.1 - 4e-13 49.4 0.1 1.1e-12 48.1 0.1 1.8 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 VBB31827.1 - 8.5e-06 25.6 10.8 1.9e-05 24.5 10.8 1.5 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 VBB31827.1 - 1.9e-05 25.0 0.1 1.9e-05 25.0 0.1 2.6 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 VBB31827.1 - 4.4e-05 23.0 4.5 4.4e-05 23.0 4.5 1.9 2 0 0 2 2 2 1 PHD-finger WHIM1 PF15612.6 VBB31827.1 - 0.0059 16.1 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 FYVE_2 PF02318.16 VBB31827.1 - 0.99 9.6 3.8 2.6 8.3 3.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 VBB31827.1 - 2.5 8.1 6.8 6 6.9 6.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4577 PF15145.6 VBB31828.1 - 0.0017 18.4 0.8 0.033 14.2 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4577) DUF3667 PF12412.8 VBB31828.1 - 2.4 7.7 7.4 0.096 12.2 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) DNA_pol_A_exo1 PF01612.20 VBB31829.1 - 2.5e-10 40.4 0.3 5e-10 39.4 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Phe_ZIP PF08916.11 VBB31829.1 - 0.48 11.2 0.1 0.48 11.2 0.1 2.6 3 0 0 3 3 3 0 Phenylalanine zipper ASC PF00858.24 VBB31830.1 - 2e-113 379.7 20.2 2.4e-113 379.4 20.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Ndr PF03096.14 VBB31831.1 - 6.1e-92 307.3 0.0 7.1e-92 307.1 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 VBB31831.1 - 2.6e-06 27.3 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB31831.1 - 0.0063 15.8 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 VBB31831.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Collagen PF01391.18 VBB31832.1 - 1.6e-24 85.4 93.1 4.4e-05 23.1 7.0 4.9 3 1 0 3 3 3 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB31832.1 - 2.1e-17 62.9 1.4 2.1e-17 62.9 1.4 2.0 2 0 0 2 2 2 1 Nematode cuticle collagen N-terminal domain BAR PF03114.18 VBB31833.1 - 1e-30 107.1 2.1 1.5e-30 106.6 2.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 VBB31833.1 - 1.3e-13 50.5 0.0 3.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB31833.1 - 2.1e-08 33.7 0.0 5.6e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 VBB31833.1 - 2.4e-08 33.5 0.0 5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain BAR_3 PF16746.5 VBB31833.1 - 1.1e-05 25.3 0.1 1.6e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF4736 PF15883.5 VBB31833.1 - 0.044 13.5 0.4 2.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Interferon PF00143.19 VBB31833.1 - 0.058 13.6 0.3 1 9.6 0.0 2.4 2 1 1 3 3 3 0 Interferon alpha/beta domain TrmE_N PF10396.9 VBB31833.1 - 0.091 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Spectrin PF00435.21 VBB31833.1 - 0.16 12.5 1.7 0.54 10.8 0.7 2.4 3 0 0 3 3 3 0 Spectrin repeat Collagen PF01391.18 VBB31834.1 - 1.3e-26 92.1 100.0 8.8e-11 41.4 40.4 4.0 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) BBL5 PF07289.11 VBB31835.1 - 1.2e-128 428.9 0.0 1.3e-128 428.7 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein bPH_3 PF14470.6 VBB31835.1 - 0.014 15.7 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.8 VBB31835.1 - 0.021 15.0 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 HAD_2 PF13419.6 VBB31837.1 - 6e-18 65.5 0.0 7.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB31837.1 - 2.6e-12 47.5 0.0 1.8e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 VBB31837.1 - 0.00042 20.3 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 VBB31837.1 - 0.097 13.1 0.0 0.26 11.7 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GDI PF00996.18 VBB31838.1 - 2e-52 178.2 0.0 1.8e-39 135.5 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor UCH PF00443.29 VBB31838.1 - 1.6e-13 50.8 0.0 4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB31838.1 - 7.6e-08 32.3 0.1 1.3e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M28 PF04389.17 VBB31839.1 - 1.2e-13 51.3 0.0 7.1e-13 48.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 VBB31839.1 - 0.00033 20.2 0.1 0.76 9.2 0.0 2.4 2 0 0 2 2 2 2 Nicastrin OST-HTH PF12872.7 VBB31840.1 - 1.7e-11 43.8 0.2 2.2e-07 30.6 0.0 3.6 3 0 0 3 3 3 2 OST-HTH/LOTUS domain TUDOR PF00567.24 VBB31840.1 - 5.6e-05 23.2 0.1 0.00019 21.5 0.1 1.9 1 0 0 1 1 1 1 Tudor domain HARE-HTH PF05066.13 VBB31840.1 - 0.086 13.2 0.1 1.4 9.4 0.0 3.0 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain DrsE_2 PF13686.6 VBB31840.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Ion_trans PF00520.31 VBB31841.1 - 8.2e-33 113.6 9.3 9.7e-33 113.4 9.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 VBB31841.1 - 1.2e-10 41.2 8.0 3.6e-10 39.7 8.0 1.8 1 1 0 1 1 1 1 Ion channel PKD_channel PF08016.12 VBB31841.1 - 0.67 8.6 5.5 0.86 8.2 5.5 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF1115 PF06544.12 VBB31842.1 - 2e-10 40.9 0.6 5.6e-10 39.5 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) RWD PF05773.22 VBB31842.1 - 0.082 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 RWD domain Toxin_TOLIP PF00087.21 VBB31843.1 - 2.8 8.3 5.5 0.99 9.7 0.5 2.4 3 0 0 3 3 3 0 Snake toxin and toxin-like protein Pribosyltran_N PF13793.6 VBB31844.1 - 3.9e-47 159.0 1.9 1.5e-46 157.1 0.2 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 VBB31844.1 - 4.5e-43 147.4 1.3 4.8e-36 124.5 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 VBB31844.1 - 3.4e-15 55.9 0.2 6.3e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 VBB31844.1 - 0.00012 21.7 0.1 0.00022 20.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF1110 PF06533.12 VBB31844.1 - 0.055 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) GoLoco PF02188.17 VBB31846.1 - 7.7e-23 79.6 19.0 1.8e-10 40.1 1.2 4.3 4 0 0 4 4 4 3 GoLoco motif TPR_12 PF13424.6 VBB31846.1 - 1.9e-15 56.9 9.5 2.9e-11 43.5 3.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB31846.1 - 3.4e-10 39.3 10.4 0.00015 21.5 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB31846.1 - 1.3e-07 31.1 8.8 0.0039 17.1 0.3 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB31846.1 - 3.8e-05 23.5 5.9 0.0018 18.4 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB31846.1 - 0.00012 21.9 12.9 0.019 15.0 0.3 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB31846.1 - 0.00067 19.4 6.6 0.037 13.9 0.6 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB31846.1 - 0.77 10.5 3.6 36 5.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM131_like PF12371.8 VBB31847.1 - 4.3e-18 65.4 5.9 1.3e-17 63.8 0.4 3.8 4 0 0 4 4 4 1 Transmembrane protein 131-like ASH PF15780.5 VBB31847.1 - 4e-15 55.8 8.8 1.4e-07 31.7 0.2 5.6 6 0 0 6 6 6 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 VBB31847.1 - 2.7e-05 24.0 0.1 0.00021 21.1 0.1 2.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 VBB31847.1 - 0.0018 18.3 0.9 1.6 8.8 0.1 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1573) TSP_1 PF00090.19 VBB31849.1 - 2.8e-11 43.5 23.3 4.8e-06 26.7 7.8 2.9 1 1 1 2 2 2 2 Thrombospondin type 1 domain Antistasin PF02822.14 VBB31849.1 - 1.4 9.7 9.0 7.8 7.2 0.1 3.5 3 1 1 4 4 4 0 Antistasin family Laminin_G_2 PF02210.24 VBB31850.1 - 9.9e-13 48.8 0.0 1.1e-12 48.7 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 VBB31850.1 - 7.1e-08 32.7 0.0 8.3e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain MFP2b PF12150.8 VBB31851.1 - 1.6e-169 563.7 0.1 1.8e-169 563.5 0.1 1.0 1 0 0 1 1 1 1 Cytosolic motility protein DUF3421 PF11901.8 VBB31851.1 - 0.0045 17.0 0.2 0.039 13.9 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3421) GP38 PF05268.11 VBB31851.1 - 0.0072 16.0 0.1 0.067 12.8 0.0 2.1 2 0 0 2 2 2 1 Phage tail fibre adhesin Gp38 zf-B_box PF00643.24 VBB31852.1 - 0.016 15.3 6.5 0.033 14.3 6.5 1.4 1 0 0 1 1 1 0 B-box zinc finger COX6B PF02297.17 VBB31853.1 - 0.71 10.2 4.1 5.2 7.4 0.2 2.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Glyco_transf_10 PF00852.19 VBB31854.1 - 8.5e-55 185.2 1.3 8.5e-55 185.2 1.3 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 VBB31854.1 - 1.8e-05 25.2 0.2 6.8e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF1623 PF07785.11 VBB31854.1 - 0.067 13.4 0.5 0.15 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) DB PF01682.19 VBB31855.1 - 8.4e-16 58.1 6.2 8.4e-16 58.1 6.2 1.9 1 1 1 2 2 2 1 DB module DUF3480 PF11979.8 VBB31856.1 - 9.6e-63 212.3 0.0 1.6e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 VBB31856.1 - 2e-16 59.9 15.8 5.1e-16 58.6 15.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger SH2 PF00017.24 VBB31857.1 - 2.4e-12 46.8 0.0 4.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain STAG PF08514.11 VBB31857.1 - 0.0038 17.1 0.2 0.008 16.1 0.2 1.6 1 0 0 1 1 1 1 STAG domain Far-17a_AIG1 PF04750.14 VBB31857.1 - 0.053 12.8 0.0 0.37 10.1 0.1 2.0 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Na_K-ATPase PF00287.18 VBB31858.1 - 6.1e-14 51.9 0.0 6.1e-14 51.9 0.0 1.4 2 0 0 2 2 2 1 Sodium / potassium ATPase beta chain DUF5464 PF17552.2 VBB31858.1 - 0.0098 16.1 1.8 0.021 15.1 1.8 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5464) MPM1 PF17234.2 VBB31858.1 - 4 7.7 8.2 6.7 6.9 8.2 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Ras PF00071.22 VBB31859.1 - 1.6e-58 196.9 0.1 2.1e-58 196.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB31859.1 - 1.2e-29 102.9 0.1 2.7e-29 101.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB31859.1 - 1.2e-11 44.3 0.0 1.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB31859.1 - 0.0032 16.9 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 VBB31859.1 - 0.0043 16.6 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PGM_PMM_II PF02879.16 VBB31860.1 - 1.6e-19 70.4 0.0 3.2e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 VBB31860.1 - 7.3e-12 45.5 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 VBB31860.1 - 7.6e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NADH_B2 PF14813.6 VBB31860.1 - 0.2 11.5 2.6 0.44 10.4 2.6 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF2680 PF10925.8 VBB31860.1 - 0.27 11.3 1.2 3.3 7.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) ERM PF00769.19 VBB31861.1 - 5.9e-30 104.9 27.9 5.9e-30 104.9 27.9 3.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 VBB31861.1 - 4.5e-21 75.0 0.0 1.4e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 VBB31861.1 - 3.4e-20 72.6 1.5 3.4e-20 72.6 1.5 2.6 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 VBB31861.1 - 9.1e-15 54.4 0.0 3.8e-14 52.4 0.0 2.1 1 0 0 1 1 1 1 FERM N-terminal domain SIMPL PF04402.14 VBB31861.1 - 0.17 12.3 5.9 0.31 11.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF541) FapA PF03961.13 VBB31861.1 - 1.8 7.1 15.1 1.9 7.0 8.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Phage_GP20 PF06810.11 VBB31861.1 - 2.4 8.0 16.4 6.4 6.6 0.4 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 AAA_23 PF13476.6 VBB31861.1 - 4.1 7.9 10.0 7.8 6.9 5.6 2.5 2 0 0 2 2 2 0 AAA domain FmiP_Thoc5 PF09766.9 VBB31862.1 - 4.4e-77 259.8 0.5 4.4e-77 259.8 0.5 1.6 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 TMEM239 PF15841.5 VBB31862.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 239 family HEPN_Apea PF18739.1 VBB31862.1 - 0.4 11.2 3.5 1.1 9.7 3.5 1.8 1 1 0 1 1 1 0 Apea-like HEPN Peptidase_S49_N PF08496.10 VBB31862.1 - 1.1 9.4 4.6 0.41 10.7 0.2 2.3 2 1 0 2 2 2 0 Peptidase family S49 N-terminal Complex1_LYR PF05347.15 VBB31863.1 - 0.00039 20.4 4.9 0.0016 18.5 0.2 2.7 2 1 1 3 3 3 2 Complex 1 protein (LYR family) Ank_5 PF13857.6 VBB31864.1 - 1.2e-17 63.7 0.1 5.2e-09 36.2 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SH3_1 PF00018.28 VBB31864.1 - 5.8e-17 61.0 0.0 9.1e-17 60.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.7 VBB31864.1 - 2.7e-16 59.9 0.0 4.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB31864.1 - 5e-16 58.8 0.1 2.7e-07 31.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB31864.1 - 3.5e-13 49.4 1.5 9.7e-08 32.1 0.4 2.9 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.6 VBB31864.1 - 1.1e-12 47.6 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB31864.1 - 1.7e-10 40.4 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 VBB31864.1 - 1.3e-05 25.2 0.1 0.28 11.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat SH3_10 PF17902.1 VBB31864.1 - 0.032 14.3 0.6 0.21 11.7 0.0 2.5 3 1 0 3 3 3 0 SH3 domain GTP_EFTU_D3 PF03143.17 VBB31865.1 - 3.2e-08 33.9 0.1 1.7e-06 28.3 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu C-terminal domain Nop10p PF04135.12 VBB31866.1 - 1.8e-13 50.3 0.4 3.5e-13 49.4 0.4 1.5 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Cyt-b5 PF00173.28 VBB31866.1 - 7.8e-10 38.8 0.3 9.5e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 VBB31866.1 - 9.3e-06 26.0 7.5 9.3e-06 26.0 7.5 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF21 PF01595.20 VBB31867.1 - 0.0046 16.7 0.7 0.0075 16.0 0.7 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Claudin_2 PF13903.6 VBB31867.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Proteasom_Rpn13 PF04683.13 VBB31867.1 - 0.067 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor DASH_Dad4 PF08650.10 VBB31868.1 - 2.3 8.2 4.8 15 5.7 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 Inositol_P PF00459.25 VBB31869.1 - 7.6e-32 110.9 0.3 1e-31 110.5 0.3 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Mito_carr PF00153.27 VBB31870.1 - 2.7e-28 97.7 0.5 1.5e-09 37.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.8 VBB31871.1 - 3.8e-13 49.0 1.6 7.7e-13 48.1 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CorA PF01544.18 VBB31871.1 - 0.026 13.9 0.4 0.026 13.9 0.4 1.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SesA PF17107.5 VBB31871.1 - 0.054 13.7 0.2 0.085 13.0 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2205 PF10224.9 VBB31871.1 - 0.28 11.2 2.0 0.31 11.1 0.4 1.9 2 0 0 2 2 2 0 Short coiled-coil protein Cullin_binding PF03556.15 VBB31872.1 - 1.6e-34 118.9 0.4 1.6e-34 118.9 0.4 1.9 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 VBB31872.1 - 7.5e-11 41.7 0.1 2.3e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 VBB31872.1 - 0.0017 18.0 0.7 0.023 14.3 1.6 2.4 2 0 0 2 2 2 1 TAP C-terminal domain Pet191_N PF10203.9 VBB31872.1 - 0.16 12.3 0.4 0.36 11.2 0.4 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CUE PF02845.16 VBB31872.1 - 0.16 11.7 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 CUE domain DUF1126 PF06565.12 VBB31873.1 - 3.8e-26 91.0 0.1 1.3e-15 57.1 0.0 3.6 3 1 0 3 3 3 3 DUF1126 PH-like domain Pkinase PF00069.25 VBB31874.1 - 8.2e-68 228.6 0.0 9.9e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31874.1 - 8.8e-32 110.4 0.0 1.9e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB31874.1 - 0.00021 20.7 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB31874.1 - 0.0037 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 VBB31874.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB31874.1 - 0.0071 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 VBB31874.1 - 0.033 13.1 0.1 0.047 12.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain LEM PF03020.15 VBB31875.1 - 6.7e-15 54.4 0.1 1.4e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 LEM domain MSC PF09402.10 VBB31875.1 - 8.4e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RIFIN PF02009.16 VBB31875.1 - 0.0034 17.3 0.3 0.0052 16.7 0.3 1.3 1 0 0 1 1 1 1 Rifin AMOP PF03782.17 VBB31877.1 - 1.6e-42 145.0 7.9 3.5e-42 143.9 7.9 1.6 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 VBB31877.1 - 2.2e-05 25.3 0.0 9.1e-05 23.3 0.0 2.2 1 0 0 1 1 1 1 Nidogen-like RRM_1 PF00076.22 VBB31878.1 - 9.9e-07 28.5 0.0 3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB31878.1 - 0.038 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 VBB31878.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 VBB31879.1 - 1.3e-22 80.4 0.0 1.6e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31879.1 - 2.7e-13 49.8 0.0 3.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB31879.1 - 2.1e-05 23.5 0.0 2.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Syncollin PF15138.6 VBB31880.1 - 0.035 14.3 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Syncollin MAGE_N PF12440.8 VBB31881.1 - 4.5 8.0 6.9 8.2 7.2 6.9 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal C_tripleX PF02363.19 VBB31882.1 - 0.00028 20.9 12.3 0.0028 17.8 2.1 9.2 7 2 2 9 9 9 4 Cysteine rich repeat Patched PF02460.18 VBB31883.1 - 5.6e-170 567.2 18.6 4.1e-94 316.3 2.9 2.1 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 VBB31883.1 - 1.1e-28 100.0 7.5 1.1e-28 100.0 7.5 3.4 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation ODV-E18 PF10717.9 VBB31883.1 - 0.1 12.5 2.5 9 6.2 0.0 2.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ig_3 PF13927.6 VBB31884.1 - 8.7e-14 51.9 0.1 1.9e-08 34.8 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 VBB31884.1 - 1.4e-08 34.9 0.0 0.0029 17.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 VBB31884.1 - 2.9e-08 33.7 0.1 9.7e-07 28.8 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 VBB31884.1 - 1.5e-05 25.1 1.0 0.4 10.9 0.0 4.2 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 VBB31884.1 - 3.9e-05 23.8 1.0 0.034 14.3 0.1 3.6 4 1 0 4 4 3 1 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB31884.1 - 0.00046 20.5 0.2 0.51 10.8 0.1 3.1 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 VBB31884.1 - 0.0012 19.0 0.5 2.6 8.4 0.0 3.4 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 VBB31884.1 - 0.019 14.8 0.2 0.93 9.3 0.0 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 VBB31884.1 - 0.072 12.7 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain EpsG PF14897.6 VBB31884.1 - 0.078 12.3 0.3 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 EpsG family ANAPC4_WD40 PF12894.7 VBB31884.1 - 0.12 12.7 0.0 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 VBB31885.1 - 3.6e-58 197.0 0.0 6e-58 196.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31885.1 - 2.4e-29 102.4 0.0 3.8e-29 101.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB31885.1 - 0.0062 16.5 0.1 0.022 14.7 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 VBB31885.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHCH PF06747.13 VBB31887.1 - 1.4e-08 34.6 2.5 2.9e-08 33.6 2.5 1.6 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 VBB31887.1 - 0.1 12.6 3.5 1.3 9.1 3.5 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like PCRF PF03462.18 VBB31888.1 - 4e-42 144.3 1.2 2.9e-41 141.5 0.0 2.2 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 VBB31888.1 - 4.7e-30 103.9 1.7 9.1e-30 103.0 1.7 1.5 1 0 0 1 1 1 1 RF-1 domain WD40 PF00400.32 VBB31889.1 - 1.3e-17 63.8 16.2 0.0002 22.1 0.7 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31889.1 - 4.7e-13 49.2 2.3 0.31 11.4 0.0 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB31889.1 - 2.1e-05 23.7 0.1 0.1 11.5 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 VBB31889.1 - 2.4e-05 24.3 0.2 0.75 9.7 0.1 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 VBB31889.1 - 0.051 13.5 0.1 18 5.4 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3545 PF12065.8 VBB31889.1 - 0.16 12.0 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) BAR PF03114.18 VBB31890.1 - 1.1e-66 224.9 11.0 1.3e-66 224.7 11.0 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 VBB31890.1 - 6.5e-05 22.2 4.9 6.5e-05 22.2 4.9 1.8 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 VBB31890.1 - 0.048 13.4 9.2 0.22 11.2 8.4 2.3 1 1 0 1 1 1 0 BAR domain of APPL family NA37 PF04245.13 VBB31890.1 - 0.13 11.8 3.3 0.19 11.2 0.1 2.4 2 2 0 2 2 2 0 37-kD nucleoid-associated bacterial protein Takusan PF04822.13 VBB31890.1 - 5.8 6.9 11.0 0.12 12.3 3.3 2.2 3 0 0 3 3 3 0 Takusan DUF2293 PF10056.9 VBB31891.1 - 0.16 12.2 0.9 0.38 11.0 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) Ipi1_N PF12333.8 VBB31892.1 - 2e-06 28.3 11.6 1.1e-05 25.9 0.4 4.2 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation HMG_box PF00505.19 VBB31892.1 - 8.3e-05 22.9 8.6 0.00044 20.6 0.0 3.8 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB31892.1 - 0.00035 21.1 1.6 0.00083 19.9 0.0 2.4 2 0 0 2 2 2 1 HMG-box domain Afi1 PF07792.12 VBB31892.1 - 0.027 15.0 3.0 0.077 13.5 3.0 1.8 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DpnI_C PF17726.1 VBB31892.1 - 0.19 11.8 2.1 0.77 9.9 1.5 2.3 2 0 0 2 2 2 0 Dam-replacing HTH domain DUF489 PF04356.12 VBB31892.1 - 1.7 8.6 6.9 0.71 9.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF489) DUF4337 PF14235.6 VBB31892.1 - 6.6 6.8 13.0 2.1 8.5 9.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TTL PF03133.15 VBB31893.1 - 4.4e-87 291.9 0.3 6.8e-87 291.3 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 VBB31893.1 - 7.7e-06 25.4 0.0 0.0084 15.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 VBB31893.1 - 1.5e-05 24.4 0.1 0.0026 17.1 0.0 2.9 2 1 1 3 3 3 1 YheC/D like ATP-grasp Methyltransf_3 PF01596.17 VBB31893.1 - 0.1 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase Bestrophin PF01062.21 VBB31895.1 - 4.4e-100 334.9 10.0 5.6e-100 334.5 10.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 VBB31896.1 - 1.2e-91 307.2 5.4 1.5e-91 306.8 5.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RF-1 PF00472.20 VBB31897.1 - 5.7e-15 55.3 1.0 1.3e-14 54.1 1.0 1.5 1 1 0 1 1 1 1 RF-1 domain US6 PF17616.2 VBB31899.1 - 0.16 11.9 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Viral unique short region 6 Lustrin_cystein PF14625.6 VBB31900.1 - 0.001 19.4 3.2 0.0031 17.9 3.2 1.8 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain ArsA_ATPase PF02374.15 VBB31901.1 - 4.7e-116 387.3 0.0 5.4e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 VBB31901.1 - 3.3e-12 46.7 0.0 1.1e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 VBB31901.1 - 4.5e-11 42.9 0.2 2.8e-10 40.4 0.2 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 VBB31901.1 - 9.4e-06 25.3 1.5 0.00021 20.9 1.2 2.6 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 VBB31901.1 - 3.8e-05 23.3 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 VBB31901.1 - 0.00028 20.4 0.0 0.0006 19.4 0.0 1.5 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 VBB31901.1 - 0.00039 20.1 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Elf1 PF05129.13 VBB31901.1 - 0.00061 19.8 0.3 0.0015 18.5 0.3 1.6 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like AAA_25 PF13481.6 VBB31901.1 - 0.0067 16.0 0.4 0.046 13.3 0.4 2.2 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 VBB31901.1 - 0.04 13.1 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 VBB31901.1 - 0.12 11.4 0.1 8.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ceramidase PF05875.12 VBB31902.1 - 4.1e-30 105.1 10.3 5.7e-30 104.6 10.3 1.0 1 0 0 1 1 1 1 Ceramidase Collagen PF01391.18 VBB31902.1 - 0.00044 19.9 25.4 25 4.7 25.4 2.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) HTH_17 PF12728.7 VBB31903.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Flavodoxin_1 PF00258.25 VBB31904.1 - 3e-25 89.1 0.0 8e-25 87.7 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 VBB31904.1 - 9.8e-22 77.6 0.0 1.6e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 VBB31904.1 - 2.8e-11 44.0 0.0 8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TRAP_alpha PF03896.16 VBB31905.1 - 0.21 10.7 3.6 0.23 10.6 3.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 VBB31905.1 - 0.68 9.2 19.7 0.8 9.0 19.7 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 VBB31905.1 - 2.7 6.1 13.9 2.9 6.0 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 VBB31905.1 - 8.9 4.5 11.7 9.9 4.3 11.7 1.0 1 0 0 1 1 1 0 CDC45-like protein 7tm_1 PF00001.21 VBB31906.1 - 5.6e-16 58.6 13.5 8.7e-16 58.0 13.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RhoGEF PF00621.20 VBB31907.1 - 9.3e-24 84.7 0.2 1.9e-23 83.6 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain TetR_C_29 PF17938.1 VBB31907.1 - 0.03 14.4 0.5 0.086 12.9 0.5 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RRM_1 PF00076.22 VBB31908.1 - 2.5e-28 97.7 0.5 4.5e-18 64.8 0.1 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.14 VBB31908.1 - 0.00011 22.2 8.1 0.12 12.4 0.0 4.3 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 VBB31908.1 - 0.049 14.2 0.0 1.6 9.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_7 PF16367.5 VBB31908.1 - 0.075 13.2 0.0 0.62 10.2 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Mad3_BUB1_I PF08311.12 VBB31908.1 - 0.12 12.3 1.8 51 3.9 0.5 4.1 3 2 0 3 3 3 0 Mad3/BUB1 homology region 1 Gal-bind_lectin PF00337.22 VBB31909.1 - 8.3e-69 229.3 0.0 3.2e-35 120.6 0.0 2.3 2 0 0 2 2 2 2 Galactoside-binding lectin Phosphodiest PF01663.22 VBB31909.1 - 5e-11 42.8 0.4 4.5e-09 36.4 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4455 PF14643.6 VBB31909.1 - 0.032 12.9 0.7 0.049 12.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) SpoOE-like PF09388.10 VBB31909.1 - 0.087 12.7 0.3 0.24 11.3 0.3 1.8 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein AAA_24 PF13479.6 VBB31909.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PQ-loop PF04193.14 VBB31910.1 - 1.3e-36 124.2 10.7 1.8e-19 69.2 1.9 2.4 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 VBB31910.1 - 0.022 15.6 1.5 0.13 13.0 0.0 2.5 3 0 0 3 3 3 0 ER lumen protein retaining receptor Cpn60_TCP1 PF00118.24 VBB31911.1 - 5.3e-156 520.1 16.6 6.1e-156 519.9 16.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP70 PF00012.20 VBB31912.1 - 3e-264 877.8 8.3 3.5e-264 877.6 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 VBB31912.1 - 1.7e-17 63.3 0.1 1.9e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 VBB31912.1 - 0.004 16.9 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 VBB31912.1 - 0.016 15.6 2.0 10 6.6 0.0 3.5 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 VBB31912.1 - 0.02 14.1 1.5 0.3 10.3 0.1 2.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 VBB31914.1 - 2.9e-38 131.4 5.7 6.7e-38 130.2 5.7 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 VBB31914.1 - 8.2e-07 28.1 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 VBB31914.1 - 0.021 13.9 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 VBB31914.1 - 0.093 12.0 0.1 0.13 11.5 0.1 1.3 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase zf-HIT PF04438.16 VBB31915.1 - 9.8e-08 31.7 9.2 9.8e-08 31.7 9.2 1.6 2 0 0 2 2 2 1 HIT zinc finger GP38 PF05268.11 VBB31915.1 - 0.13 11.9 0.5 0.21 11.2 0.5 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 EGF_MSP1_1 PF12946.7 VBB31917.1 - 0.046 13.8 0.3 1.9 8.6 0.0 3.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 ALG3 PF05208.13 VBB31918.1 - 2.1e-13 50.5 1.8 3e-13 49.9 1.8 1.2 1 0 0 1 1 1 1 ALG3 protein Methyltransf_11 PF08241.12 VBB31918.1 - 7e-12 45.8 0.0 1.9e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB31918.1 - 2.9e-11 43.5 0.0 4.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB31918.1 - 8.5e-11 42.4 0.0 1.8e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB31918.1 - 1.4e-08 35.4 0.0 3.4e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB31918.1 - 4.5e-05 23.3 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 VBB31918.1 - 0.00014 21.4 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 VBB31918.1 - 0.00034 20.6 0.1 0.00059 19.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB31918.1 - 0.0022 17.4 0.0 0.0061 15.9 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 VBB31918.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Hist_deacetyl PF00850.19 VBB31919.1 - 0.0033 17.0 0.0 0.004 16.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Collagen PF01391.18 VBB31920.1 - 9.9e-09 34.8 16.6 1.5e-08 34.3 16.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF229 PF02995.17 VBB31922.1 - 5.7e-40 137.4 1.1 4.6e-32 111.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF229) Asp PF00026.23 VBB31923.1 - 5.8e-116 387.3 0.5 6.8e-116 387.1 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 VBB31923.1 - 4.2e-10 40.1 0.0 7.3e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 VBB31923.1 - 8.1e-05 22.5 0.0 0.00033 20.5 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 VBB31923.1 - 0.04 14.5 0.0 31 5.3 0.0 3.1 3 0 0 3 3 3 0 Aspartyl protease NOT2_3_5 PF04153.18 VBB31924.1 - 2.4e-40 137.7 8.1 2.4e-40 137.7 8.1 2.5 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Not3 PF04065.15 VBB31924.1 - 1.3e-30 106.5 10.8 1.3e-30 106.5 10.8 2.5 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component BRF1 PF07741.13 VBB31924.1 - 9.8 6.6 14.3 19 5.7 1.3 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CH PF00307.31 VBB31925.1 - 0.079 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain Ldl_recept_a PF00057.18 VBB31926.1 - 2.7e-37 126.7 62.4 4.7e-10 39.5 7.5 4.5 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A Pkinase PF00069.25 VBB31928.1 - 1.2e-63 214.9 0.0 1.7e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB31928.1 - 1.1e-31 110.1 0.0 1.9e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB31928.1 - 0.00013 22.0 0.1 0.00058 19.9 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 VBB31928.1 - 0.00047 19.2 0.0 0.00047 19.2 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 VBB31928.1 - 0.013 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 VBB31928.1 - 0.066 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 VBB31928.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5347 PF17282.2 VBB31929.1 - 0.057 13.7 1.5 0.076 13.3 0.9 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5347) Metallophos PF00149.28 VBB31930.1 - 3.3e-11 44.1 0.0 4.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thump_like PF18096.1 VBB31930.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 THUMP domain-like DEAD PF00270.29 VBB31931.1 - 2.7e-19 69.6 0.4 9e-19 67.9 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB31931.1 - 2.1e-18 66.7 0.2 6.8e-13 48.9 0.0 3.9 4 1 0 4 4 4 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 VBB31931.1 - 4.9e-11 43.2 4.6 2.1e-10 41.2 2.1 3.1 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 VBB31931.1 - 2.8e-06 27.4 1.0 1e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2027 PF09640.10 VBB31931.1 - 0.009 15.6 1.0 0.02 14.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2027) KIX_2 PF16987.5 VBB31931.1 - 0.21 11.6 2.4 0.8 9.7 2.4 2.0 1 0 0 1 1 1 0 KIX domain Gpi16 PF04113.14 VBB31932.1 - 5.5e-90 302.4 0.0 2.2e-60 204.7 0.0 2.0 2 0 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Phage_holin_3_7 PF05449.11 VBB31932.1 - 0.12 12.4 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 PGI PF00342.19 VBB31933.1 - 4e-172 573.2 0.2 5.7e-172 572.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Tsg PF04668.12 VBB31933.1 - 1.7e-24 87.0 4.7 3.8e-24 85.9 4.7 1.5 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region CPSase_L_D3 PF02787.19 VBB31933.1 - 0.073 13.4 0.3 0.39 11.1 0.1 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Tam41_Mmp37 PF09139.11 VBB31935.1 - 1.3e-10 41.3 0.1 1.4e-10 41.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Phage_portal PF04860.12 VBB31935.1 - 0.062 12.5 0.1 0.069 12.3 0.1 1.0 1 0 0 1 1 1 0 Phage portal protein GLTP PF08718.11 VBB31936.1 - 2e-35 122.2 0.1 3.4e-35 121.5 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF148 PF02520.17 VBB31936.1 - 0.029 14.5 0.3 0.068 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 NACHT PF05729.12 VBB31936.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 NACHT domain Peptidase_C2 PF00648.21 VBB31938.1 - 1.7e-47 161.9 0.1 3.3e-47 160.9 0.1 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 VBB31938.1 - 1.9e-14 53.5 11.6 1.9e-07 31.0 1.6 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 VBB31938.1 - 3.4e-12 46.8 1.0 4.8e-09 36.6 0.0 4.3 3 2 1 4 4 4 1 Calpain large subunit, domain III FKBP_N_2 PF18023.1 VBB31938.1 - 0.068 13.3 0.2 0.27 11.4 0.1 2.0 1 1 1 2 2 2 0 BDBT FKBP like N-terminal CAP PF00188.26 VBB31939.1 - 1.1e-22 81.2 1.4 1.3e-22 80.9 1.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Nodulin_late PF07127.11 VBB31939.1 - 4.8 7.6 5.6 1.1 9.7 1.6 2.0 2 0 0 2 2 2 0 Late nodulin protein zf-RING_2 PF13639.6 VBB31941.1 - 4.6e-06 26.8 4.1 4.6e-06 26.8 4.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 VBB31941.1 - 0.00014 21.5 1.2 0.00014 21.5 1.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 VBB31941.1 - 0.00025 20.6 3.3 0.00025 20.6 3.3 2.5 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 VBB31941.1 - 0.0015 18.8 3.4 0.0015 18.8 3.4 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 VBB31941.1 - 0.0033 17.4 3.0 0.0033 17.4 3.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB31941.1 - 0.0066 16.5 2.6 0.0066 16.5 2.6 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 VBB31941.1 - 0.013 15.4 3.4 0.013 15.4 3.4 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 VBB31941.1 - 0.018 14.9 0.7 0.018 14.9 0.7 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB31941.1 - 0.033 14.2 5.2 0.076 13.1 5.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-B_box PF00643.24 VBB31941.1 - 1.1 9.5 19.7 1 9.6 11.3 3.0 3 0 0 3 3 3 0 B-box zinc finger Molybdopterin PF00384.22 VBB31942.1 - 6.9e-65 219.7 0.0 3e-63 214.3 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 VBB31942.1 - 9.2e-18 64.1 0.0 1.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 VBB31942.1 - 1.9e-15 56.1 0.1 1.9e-15 56.1 0.1 2.4 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 VBB31942.1 - 2.8e-11 43.9 0.0 6.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 VBB31942.1 - 2.5e-09 36.9 1.3 3e-09 36.7 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 VBB31942.1 - 9.3e-05 22.2 0.4 0.0094 15.7 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 VBB31942.1 - 0.29 11.0 1.9 8.4 6.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain C_GCAxxG_C_C PF09719.10 VBB31943.1 - 0.1 12.9 0.2 0.11 12.8 0.2 1.0 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) HLH PF00010.26 VBB31944.1 - 1.6e-08 34.3 1.3 3.3e-06 27.0 0.1 2.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Paralemmin PF03285.15 VBB31944.1 - 0.00026 20.7 1.2 0.00069 19.3 1.2 1.7 1 0 0 1 1 1 1 Paralemmin Cortex-I_coil PF09304.10 VBB31944.1 - 0.0072 16.5 1.6 0.0072 16.5 1.6 1.9 2 0 0 2 2 2 1 Cortexillin I, coiled coil Tropomyosin_1 PF12718.7 VBB31944.1 - 0.027 14.6 2.0 0.083 13.0 2.0 1.8 1 0 0 1 1 1 0 Tropomyosin like Glyco_transf_25 PF01755.17 VBB31944.1 - 0.066 13.1 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Sin3_corepress PF08295.12 VBB31944.1 - 0.067 13.3 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor CLZ PF16526.5 VBB31944.1 - 0.091 13.1 1.1 0.34 11.3 1.1 2.0 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 VBB31944.1 - 0.11 12.7 3.5 0.35 11.1 3.5 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 VBB31944.1 - 0.14 11.9 2.1 0.54 10.1 2.1 2.1 1 0 0 1 1 1 0 Septum formation initiator SseC PF04888.12 VBB31944.1 - 0.2 11.2 3.3 0.37 10.3 3.3 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ZapB PF06005.12 VBB31944.1 - 0.22 12.0 3.5 0.99 9.9 3.5 2.2 1 0 0 1 1 1 0 Cell division protein ZapB DUF3847 PF12958.7 VBB31944.1 - 1.1 9.4 6.1 0.16 12.1 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) PHO4 PF01384.20 VBB31945.1 - 8.5e-43 146.7 4.6 9.5e-43 146.5 4.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Formin_GBD_N PF18382.1 VBB31946.1 - 1.3e-34 118.6 0.1 1.5e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain zf-RING_5 PF14634.6 VBB31946.1 - 0.095 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 zinc-RING finger domain FH2 PF02181.23 VBB31947.1 - 1.1e-22 80.7 4.2 1.2e-22 80.5 0.1 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 VBB31947.1 - 4.6e-05 23.1 1.2 0.0001 22.0 1.2 1.5 1 0 0 1 1 1 1 Diaphanous FH3 Domain T2SSE PF00437.20 VBB31947.1 - 0.11 11.6 0.3 0.23 10.5 0.3 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 VBB31948.1 - 1.4e-28 100.0 0.0 2.8e-28 99.1 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 VBB31948.1 - 1.9e-07 31.6 0.0 4.9e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 VBB31948.1 - 5.7e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 VBB31948.1 - 8.6e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 VBB31948.1 - 1.8e-05 25.2 0.0 3.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MRP_L53 PF10780.9 VBB31948.1 - 0.00014 21.9 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 dNK PF01712.19 VBB31948.1 - 0.00073 19.4 0.5 0.0088 15.9 0.1 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase RuvB_N PF05496.12 VBB31948.1 - 0.00079 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB31948.1 - 0.00081 19.7 0.0 0.0026 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB31948.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 VBB31948.1 - 0.003 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 VBB31948.1 - 0.0056 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 NTPase SKI PF01202.22 VBB31948.1 - 0.0081 16.3 0.0 0.027 14.6 0.0 1.7 1 1 1 2 2 2 1 Shikimate kinase AAA_14 PF13173.6 VBB31948.1 - 0.0091 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 VBB31948.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_33 PF13671.6 VBB31948.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 VBB31948.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase RNA_helicase PF00910.22 VBB31948.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 VBB31948.1 - 0.024 15.0 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 VBB31948.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 VBB31948.1 - 0.031 13.3 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 VBB31948.1 - 0.033 13.9 0.7 0.16 11.7 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADK PF00406.22 VBB31948.1 - 0.054 13.6 0.0 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase ATPase PF06745.13 VBB31948.1 - 0.058 12.7 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 VBB31948.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 VBB31948.1 - 0.094 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 VBB31948.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 VBB31948.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 VBB31948.1 - 0.13 11.6 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit KIF1B PF12423.8 VBB31948.1 - 0.15 12.5 0.9 7.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Kinesin protein 1B AAA_7 PF12775.7 VBB31948.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 VBB31948.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 VBB31948.1 - 0.21 11.0 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MeaB PF03308.16 VBB31948.1 - 0.26 10.2 0.1 0.41 9.6 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GED PF02212.18 VBB31948.1 - 0.28 11.4 0.9 0.92 9.7 0.1 1.9 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_30 PF13604.6 VBB31948.1 - 0.32 10.7 0.2 0.52 10.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain RLL PF10036.9 VBB31949.1 - 9.5e-74 248.5 3.3 1.1e-73 248.3 3.3 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Methyltransf_11 PF08241.12 VBB31949.1 - 0.01 16.4 0.0 0.03 15.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 VBB31949.1 - 0.053 14.2 0.1 0.27 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain INCA1 PF15142.6 VBB31949.1 - 0.11 12.6 0.1 0.39 10.7 0.1 1.9 1 1 1 2 2 2 0 INCA1 PPTA PF01239.22 VBB31950.1 - 1.5e-48 161.2 16.9 1.7e-11 43.5 0.4 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 VBB31950.1 - 0.011 16.1 1.0 5.7 7.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_trans_CmpB PF06541.11 VBB31950.1 - 0.17 12.1 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Putative ABC-transporter type IV Cue1_U7BR PF18499.1 VBB31950.1 - 0.27 11.3 4.9 1.4 9.0 0.0 3.7 3 1 1 4 4 4 0 Ubc7p-binding region of Cue1 DUF4219 PF13961.6 VBB31950.1 - 6.4 6.6 8.9 24 4.7 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) PseudoU_synth_1 PF01416.20 VBB31951.1 - 1.8e-31 108.8 0.0 4.3e-29 101.1 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase I-set PF07679.16 VBB31952.1 - 2.2e-13 50.1 0.1 2.6e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB31952.1 - 3.1e-10 40.5 0.3 7e-10 39.4 0.1 1.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 VBB31952.1 - 5.3e-05 23.4 0.6 0.001 19.2 0.6 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 VBB31952.1 - 9e-05 22.7 0.4 0.00015 22.0 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 VBB31952.1 - 0.0001 22.4 0.8 0.00016 21.8 0.3 1.5 1 1 1 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 VBB31952.1 - 0.00099 19.1 0.1 0.0018 18.3 0.1 1.6 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain DUF1364 PF07102.12 VBB31952.1 - 0.03 14.1 0.1 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) FKBP_C PF00254.28 VBB31954.1 - 1.5e-52 175.9 0.0 1.4e-27 95.9 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Synaptobrevin PF00957.21 VBB31955.1 - 1.3e-34 117.9 6.1 1.4e-34 117.7 6.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 VBB31955.1 - 0.0025 17.9 0.1 0.0029 17.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF3671 PF12420.8 VBB31955.1 - 0.0094 16.0 0.5 0.013 15.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function LMBR1 PF04791.16 VBB31955.1 - 0.012 14.6 0.3 0.014 14.3 0.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PRIMA1 PF16101.5 VBB31955.1 - 0.016 15.2 1.5 0.028 14.4 1.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RIFIN PF02009.16 VBB31955.1 - 0.023 14.6 0.8 0.026 14.4 0.8 1.0 1 0 0 1 1 1 0 Rifin Fusion_gly PF00523.18 VBB31955.1 - 0.035 12.4 1.9 0.042 12.1 1.9 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Orf78 PF06024.12 VBB31955.1 - 0.042 14.1 0.6 0.053 13.8 0.6 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF3619 PF12279.8 VBB31955.1 - 0.056 13.8 0.3 0.084 13.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) Baculo_F PF12259.8 VBB31955.1 - 0.065 11.7 1.1 0.076 11.5 1.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF2207 PF09972.9 VBB31955.1 - 0.075 11.8 0.1 0.079 11.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Integrase_H2C2 PF17921.1 VBB31955.1 - 0.078 13.1 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Integrase zinc binding domain Sigma_reg_N PF13800.6 VBB31955.1 - 0.41 11.0 4.8 0.67 10.3 4.8 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syntaxin-18_N PF10496.9 VBB31956.1 - 1.3e-06 28.6 2.3 1.3e-06 28.6 2.3 2.7 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF737 PF05300.11 VBB31956.1 - 0.036 14.4 8.7 0.81 10.0 8.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF737) DNA_topoisoIV PF00521.20 VBB31956.1 - 5.6 5.7 14.5 0.66 8.8 9.8 1.8 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A eRF1_2 PF03464.15 VBB31957.1 - 3.6e-47 160.0 0.1 5.9e-47 159.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 VBB31957.1 - 1.2e-34 119.2 0.3 3.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 VBB31957.1 - 1.2e-18 67.3 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 VBB31957.1 - 1.8e-09 38.0 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 VBB31957.1 - 7.8e-09 35.9 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 ANF_receptor PF01094.28 VBB31958.1 - 7.3e-64 216.1 0.0 1.1e-63 215.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 VBB31958.1 - 3.9e-47 161.0 29.0 6.6e-47 160.2 29.0 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 VBB31958.1 - 6.6e-10 38.8 12.3 6.6e-10 38.8 12.3 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 VBB31958.1 - 6.2e-05 22.8 0.1 9.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein WD40 PF00400.32 VBB31959.1 - 1.8e-12 47.5 5.6 0.079 13.9 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB31959.1 - 0.00045 20.4 0.2 1.3 9.4 0.0 4.5 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nsp1_C PF05064.13 VBB31960.1 - 1.3e-14 54.0 3.7 1.3e-14 54.0 3.7 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 VBB31960.1 - 0.018 15.9 114.1 1.1 10.1 16.6 6.8 1 1 4 5 5 5 0 Nucleoporin FG repeat region BLOC1_2 PF10046.9 VBB31960.1 - 3 8.2 9.9 1.3 9.4 1.7 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MFP2b PF12150.8 VBB31961.1 - 3.7e-165 549.3 0.0 4.2e-165 549.1 0.0 1.0 1 0 0 1 1 1 1 Cytosolic motility protein DUF3421 PF11901.8 VBB31961.1 - 0.0017 18.4 0.2 0.015 15.3 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3421) GP38 PF05268.11 VBB31961.1 - 0.012 15.3 0.0 4.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 EGF_alliinase PF04863.13 VBB31961.1 - 0.078 13.4 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain DUF4518 PF15008.6 VBB31962.1 - 4.7 6.3 14.8 0.14 11.3 7.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Tim54 PF11711.8 VBB31963.1 - 0.25 10.1 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BTB_2 PF02214.22 VBB31964.1 - 3.4e-11 43.4 0.0 7.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 VBB31966.1 - 3.6e-54 183.9 0.0 9.7e-54 182.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 VBB31966.1 - 1.8e-41 140.5 0.1 5.9e-41 138.8 0.0 1.9 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 VBB31966.1 - 4.8e-26 91.6 0.0 5.7e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 VBB31966.1 - 3.4e-05 23.3 0.0 0.15 11.3 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 VBB31966.1 - 0.00028 19.9 0.3 0.00043 19.3 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 VBB31966.1 - 0.00052 19.7 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 VBB31966.1 - 0.00089 18.1 0.1 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 VBB31966.1 - 0.0032 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB31966.1 - 0.029 14.3 0.4 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 VBB31966.1 - 0.035 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Cyclin_N PF00134.23 VBB31967.1 - 2.7e-08 33.6 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 VBB31967.1 - 0.037 14.1 0.0 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 VBB31968.1 - 0.0046 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 VBB31968.1 - 0.018 14.8 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Cyclin, N-terminal domain SET PF00856.28 VBB31969.1 - 1.3e-21 77.8 0.4 5.2e-21 75.8 0.4 2.1 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 VBB31969.1 - 5.5e-10 39.5 20.3 5.5e-10 39.5 20.3 4.4 4 1 1 5 5 5 1 CXC domain Metallophos PF00149.28 VBB31969.1 - 0.00029 21.4 0.0 0.00053 20.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Myb_DNA-binding PF00249.31 VBB31969.1 - 0.038 14.2 0.1 1.8 8.8 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain TCR PF03638.15 VBB31969.1 - 8.3 6.8 38.4 1 9.7 15.8 3.1 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Gal-bind_lectin PF00337.22 VBB31970.1 - 7.6e-32 109.7 0.1 1.1e-18 67.1 0.0 2.9 2 1 0 2 2 2 2 Galactoside-binding lectin FAS_meander PF17951.1 VBB31970.1 - 0.038 13.8 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain Pro_isomerase PF00160.21 VBB31971.1 - 9.5e-44 149.4 0.6 1.9e-23 83.5 0.1 2.4 2 1 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 VBB31972.1 - 8.8e-40 134.4 0.0 7.4e-13 48.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB31972.1 - 6.5e-08 32.2 0.0 0.00055 19.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 VBB31972.1 - 2.1e-06 27.7 0.5 1 9.5 0.0 4.3 3 1 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 VBB31972.1 - 0.00014 21.6 0.0 0.27 11.1 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Hep_59 PF07052.11 VBB31973.1 - 1.8e-20 73.7 5.2 1.8e-20 73.7 5.2 2.0 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 EF-hand_7 PF13499.6 VBB31973.1 - 0.051 14.0 0.0 0.24 11.9 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair UPF0767 PF15990.5 VBB31973.1 - 1.4 9.1 3.4 1.4 9.1 0.4 2.5 2 0 0 2 2 2 0 UPF0767 family Tropomyosin PF00261.20 VBB31975.1 - 9.3e-68 228.1 44.9 1.3e-34 119.7 16.3 2.0 2 0 0 2 2 2 2 Tropomyosin Myosin_tail_1 PF01576.19 VBB31975.1 - 7.4e-07 27.4 36.1 7.8e-05 20.7 21.4 2.0 1 1 1 2 2 2 2 Myosin tail Laminin_II PF06009.12 VBB31975.1 - 1.1e-05 25.4 24.0 0.0049 16.9 6.1 2.9 1 1 2 3 3 3 2 Laminin Domain II Tropomyosin_1 PF12718.7 VBB31975.1 - 0.0029 17.7 42.5 5.1 7.3 16.4 3.9 1 1 1 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.9 VBB31975.1 - 0.013 15.6 42.3 0.02 14.9 15.3 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 VBB31975.1 - 0.023 14.9 31.4 0.27 11.5 5.9 5.1 1 1 4 5 5 5 0 Haemolysin XhlA Flagellin_N PF00669.20 VBB31975.1 - 0.031 14.4 2.4 0.031 14.4 2.4 2.4 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF1664 PF07889.12 VBB31975.1 - 0.04 13.9 20.0 0.39 10.8 4.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Vps53_N PF04100.12 VBB31975.1 - 0.11 11.4 15.5 0.036 13.0 6.7 2.3 1 1 0 2 2 2 0 Vps53-like, N-terminal RasGAP_C PF03836.15 VBB31975.1 - 0.12 12.5 16.8 0.28 11.3 8.6 2.5 1 1 1 2 2 2 0 RasGAP C-terminus TPR_MLP1_2 PF07926.12 VBB31975.1 - 0.19 11.8 40.0 1.4 9.0 15.4 3.1 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 VBB31975.1 - 0.27 11.7 19.1 0.11 13.0 4.2 2.6 1 1 2 3 3 3 0 Type III cell invasion protein SipB APG6_N PF17675.1 VBB31975.1 - 0.27 11.8 44.3 0.23 12.0 16.5 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 VBB31975.1 - 0.27 10.5 27.5 0.21 10.9 9.6 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3450) FlxA PF14282.6 VBB31975.1 - 0.37 10.8 21.2 2.6 8.1 0.2 4.1 2 2 1 4 4 4 0 FlxA-like protein DUF745 PF05335.13 VBB31975.1 - 0.37 10.5 30.4 0.47 10.1 10.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF4472 PF14739.6 VBB31975.1 - 0.38 11.5 32.9 0.34 11.7 10.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) HisKA_3 PF07730.13 VBB31975.1 - 0.46 11.0 0.1 0.46 11.0 0.1 4.4 3 2 1 4 4 4 0 Histidine kinase DUF724 PF05266.14 VBB31975.1 - 0.57 10.0 31.8 2.5 7.9 16.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 VBB31975.1 - 0.93 9.1 40.1 3.1 7.4 25.3 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 VBB31975.1 - 1.2 9.3 19.9 0.12 12.5 4.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 VBB31975.1 - 1.4 9.6 24.3 0.87 10.2 5.3 4.1 2 1 2 4 4 4 0 SlyX Noelin-1 PF12308.8 VBB31975.1 - 1.5 8.9 13.9 0.37 10.8 1.4 3.3 1 1 3 4 4 4 0 Neurogenesis glycoprotein EMP24_GP25L PF01105.24 VBB31975.1 - 1.6 8.6 21.5 0.069 13.1 4.1 3.5 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.16 VBB31975.1 - 1.7 9.1 23.0 0.44 11.0 7.4 3.2 1 1 1 2 2 1 0 Protein of unknown function DUF16 MtrG PF04210.13 VBB31975.1 - 1.8 8.5 4.9 6.4 6.7 0.2 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Baculo_PEP_C PF04513.12 VBB31975.1 - 1.8 8.6 7.5 1.2 9.2 2.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 VBB31975.1 - 2 8.8 23.0 7 7.0 9.6 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HOOK PF05622.12 VBB31975.1 - 2.2 6.3 35.3 16 3.5 35.3 1.9 1 1 0 1 1 1 0 HOOK protein HrpB7 PF09486.10 VBB31975.1 - 2.3 8.6 30.0 1.2 9.5 9.0 3.0 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Spectrin PF00435.21 VBB31975.1 - 2.7 8.5 26.2 11 6.6 4.4 3.7 1 1 2 3 3 3 0 Spectrin repeat Fez1 PF06818.15 VBB31975.1 - 2.9 8.3 32.3 8.6 6.8 16.1 2.2 1 1 1 2 2 2 0 Fez1 BORCS7 PF16088.5 VBB31975.1 - 3.6 7.9 12.1 2.3 8.5 3.1 3.0 1 1 3 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF3492 PF11997.8 VBB31975.1 - 3.7 7.2 10.4 0.16 11.6 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) ADIP PF11559.8 VBB31975.1 - 4 7.5 27.6 1.6 8.8 11.5 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 VBB31975.1 - 4.8 7.8 27.0 2 9.0 8.8 3.5 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 TMPIT PF07851.13 VBB31975.1 - 4.9 6.3 22.9 3.1 7.0 9.3 2.2 1 1 1 2 2 2 0 TMPIT-like protein AAA_13 PF13166.6 VBB31975.1 - 5.5 5.5 25.3 30 3.1 25.3 2.0 1 1 0 1 1 1 0 AAA domain EzrA PF06160.12 VBB31975.1 - 9.2 4.3 31.5 0.78 7.8 6.9 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Tropomyosin PF00261.20 VBB31976.1 - 3.3e-32 111.8 27.9 3e-28 98.8 19.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 VBB31976.1 - 3.9e-15 56.3 22.9 9.7e-15 55.0 13.7 2.3 2 1 0 2 2 2 2 Tropomyosin like Cue1_U7BR PF18499.1 VBB31976.1 - 0.021 14.8 2.0 1 9.5 0.5 2.5 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 DUF4446 PF14584.6 VBB31976.1 - 0.027 14.5 4.7 0.97 9.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SMN PF06003.12 VBB31976.1 - 0.27 10.5 1.0 0.35 10.1 1.0 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Laminin_II PF06009.12 VBB31976.1 - 0.39 10.7 8.5 4.3 7.3 4.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Sugarporin_N PF11471.8 VBB31976.1 - 0.58 10.2 17.6 0.053 13.5 2.7 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension ERM PF00769.19 VBB31976.1 - 0.59 9.9 20.7 0.73 9.6 20.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BST2 PF16716.5 VBB31976.1 - 0.92 10.1 9.6 1.9 9.1 5.8 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Borrelia_P83 PF05262.11 VBB31976.1 - 1.3 7.4 11.0 1.7 7.1 11.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DASH_Spc19 PF08287.11 VBB31976.1 - 6.2 6.7 14.9 1 9.2 9.8 1.9 1 1 1 2 2 2 0 Spc19 DUF5320 PF17253.2 VBB31976.1 - 8.3 7.5 5.4 2 9.5 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) CENP-Q PF13094.6 VBB31976.1 - 9.3 6.4 22.4 14 5.8 16.0 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lectin_C PF00059.21 VBB31977.1 - 1.9e-34 118.6 11.9 9.1e-14 52.1 1.8 4.3 3 3 0 3 3 3 3 Lectin C-type domain Chordopox_A33R PF05966.12 VBB31977.1 - 9.7e-05 21.7 2.2 0.014 14.7 0.2 2.5 2 0 0 2 2 2 2 Chordopoxvirus A33R protein KAP PF05804.12 VBB31978.1 - 1.8e-162 542.1 25.0 3.1e-162 541.3 25.0 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) RRM_1 PF00076.22 VBB31980.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Membr_traf_MHD PF10540.9 VBB31981.1 - 8.9e-31 107.1 4.8 8.9e-31 107.1 4.8 3.1 2 2 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 VBB31981.1 - 1.4e-12 47.8 0.0 3.7e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Dynamin_M PF01031.20 VBB31981.1 - 0.00057 19.2 4.6 0.058 12.6 1.5 2.5 1 1 1 2 2 2 2 Dynamin central region INTS5_N PF14837.6 VBB31981.1 - 0.052 13.2 1.6 0.26 10.9 1.6 2.2 1 1 0 1 1 1 0 Integrator complex subunit 5 N-terminus Wbp11 PF09429.10 VBB31981.1 - 0.11 12.8 0.2 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 WW domain binding protein 11 FliG_C PF01706.16 VBB31981.1 - 1.1 9.5 3.6 33 4.7 0.1 3.1 3 0 0 3 3 3 0 FliG C-terminal domain DUF1804 PF08822.11 VBB31981.1 - 2.5 8.1 4.6 4.9 7.1 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1804) MARVEL PF01284.23 VBB31982.1 - 1.4e-05 25.2 14.1 1.8e-05 24.8 14.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_3_6 PF07332.11 VBB31982.1 - 4.2 7.4 4.8 7.9 6.6 4.8 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Androgen_recep PF02166.16 VBB31983.1 - 2.2 7.0 6.3 3.2 6.5 6.3 1.2 1 0 0 1 1 1 0 Androgen receptor Neur_chan_LBD PF02931.23 VBB31984.1 - 7e-75 251.2 2.8 9.3e-75 250.8 2.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB31984.1 - 9.1e-50 169.9 6.6 3.2e-49 168.2 6.6 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_2 PF13903.6 VBB31984.1 - 0.15 11.8 1.4 0.26 11.0 1.4 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Motile_Sperm PF00635.26 VBB31986.1 - 1.6e-26 92.2 0.0 1.8e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PTP_tm PF18861.1 VBB31987.1 - 0.0039 17.2 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Lectin_C PF00059.21 VBB31987.1 - 0.011 16.4 0.4 0.011 16.4 0.4 1.6 2 0 0 2 2 2 0 Lectin C-type domain ETX_MTX2 PF03318.13 VBB31988.1 - 4.3e-08 33.2 0.0 5.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Laminin_G_2 PF02210.24 VBB31990.1 - 1.3e-78 261.7 1.9 6.6e-21 75.2 0.1 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 VBB31990.1 - 1.7e-68 228.8 0.0 2.9e-22 79.3 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_EGF PF00053.24 VBB31990.1 - 3.9e-45 151.8 135.0 2.8e-10 40.2 10.6 8.6 6 2 2 8 8 8 8 Laminin EGF domain Laminin_B PF00052.18 VBB31990.1 - 1.3e-24 86.6 0.0 3e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_II PF06009.12 VBB31990.1 - 8.9e-09 35.5 6.4 8.9e-09 35.5 6.4 2.8 2 1 1 3 3 3 1 Laminin Domain II Laminin_G_3 PF13385.6 VBB31990.1 - 2.4e-08 34.3 1.7 0.44 10.7 0.0 5.0 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily Gas_vesicle_C PF01304.17 VBB31990.1 - 0.06 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain HsbA PF12296.8 VBB31990.1 - 4.3 7.8 11.0 0.042 14.3 0.5 2.8 3 0 0 3 3 3 0 Hydrophobic surface binding protein A 7tm_1 PF00001.21 VBB31992.1 - 1.9e-07 30.7 20.2 4.2e-07 29.6 20.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sld5 PF05916.11 VBB31993.1 - 2.6e-17 63.2 0.0 3.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein BTB PF00651.31 VBB31994.1 - 0.022 15.0 0.0 0.065 13.5 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain DAP PF15228.6 VBB31995.1 - 4.7e-21 75.8 2.0 5.4e-21 75.6 2.0 1.0 1 0 0 1 1 1 1 Death-associated protein Neur_chan_memb PF02932.16 VBB31997.1 - 1.7e-19 70.8 0.3 4e-18 66.3 0.3 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region EMP70 PF02990.16 VBB31998.1 - 4.3e-169 563.5 4.8 6.1e-169 563.0 4.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ACAS_N PF16177.5 VBB31998.1 - 0.22 11.5 1.1 0.41 10.6 1.1 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus MtN3_slv PF03083.16 VBB31999.1 - 0.017 15.1 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange ASC PF00858.24 VBB32000.1 - 2.1e-66 224.7 10.8 2.1e-66 224.7 10.8 1.5 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel Guanylate_kin PF00625.21 VBB32001.1 - 5.6e-14 52.2 0.0 6.2e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RSN1_TM PF13967.6 VBB32002.1 - 0.095 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport CLN3 PF02487.17 VBB32002.1 - 7.8 5.4 13.7 0.098 11.7 2.3 2.0 2 0 0 2 2 2 0 CLN3 protein FAM176 PF14851.6 VBB32002.1 - 9.9 5.8 17.7 1.9 8.1 1.8 2.3 2 0 0 2 2 2 0 FAM176 family Peptidase_C1 PF00112.23 VBB32003.1 - 5.3e-58 196.7 8.1 9.4e-58 195.9 8.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease DUF236 PF03057.14 VBB32003.1 - 4e-48 161.0 22.4 2.1e-17 62.7 2.3 3.5 3 0 0 3 3 3 3 DUF236 repeat Propeptide_C1 PF08127.13 VBB32003.1 - 1.2e-07 31.5 0.1 2.9e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide C2 PF00168.30 VBB32004.1 - 6.1e-16 58.6 0.1 1.3e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 VBB32004.1 - 0.0047 17.5 0.0 0.25 12.0 0.0 2.6 2 0 0 2 2 2 1 Putative heavy-metal-binding Ras PF00071.22 VBB32005.1 - 1.4e-54 184.0 0.0 1.7e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB32005.1 - 1.4e-22 80.2 0.0 2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB32005.1 - 7.4e-09 35.3 0.0 9.1e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family NUDE_C PF04880.13 VBB32006.1 - 1.7e-09 38.4 5.9 1.7e-09 38.4 5.9 3.6 2 2 1 3 3 3 1 NUDE protein, C-terminal conserved region APG6_N PF17675.1 VBB32006.1 - 0.0016 19.0 24.8 0.0016 19.0 24.8 2.7 1 1 1 2 2 2 1 Apg6 coiled-coil region DUF4897 PF16238.5 VBB32006.1 - 0.42 10.4 3.8 1 9.2 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) WD40_alt PF14077.6 VBB32006.1 - 1.4 8.8 5.8 0.32 10.9 0.5 2.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif UPF0184 PF03670.13 VBB32006.1 - 5 7.6 8.1 0.93 9.9 3.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Cse1 PF08506.10 VBB32008.1 - 9.6e-118 393.2 7.0 4.5e-117 391.0 7.0 2.1 1 1 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 VBB32008.1 - 1.7e-55 188.3 3.5 4e-55 187.1 3.5 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 VBB32008.1 - 2.9e-10 39.9 0.0 7.8e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 VBB32008.1 - 0.0044 17.1 3.2 0.085 12.9 0.2 3.2 2 0 0 2 2 2 1 Exportin 1-like protein DUF3177 PF11375.8 VBB32008.1 - 0.021 14.6 0.2 0.074 12.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) DUF2247 PF10004.9 VBB32008.1 - 0.11 12.2 1.3 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Myotub-related PF06602.14 VBB32009.1 - 1.7e-72 244.3 0.5 2.4e-72 243.8 0.5 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 VBB32009.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 3-PAP PF12578.8 VBB32009.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein Y_phosphatase PF00102.27 VBB32009.1 - 0.00092 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB32009.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB32009.1 - 0.046 13.9 1.0 0.44 10.7 0.0 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate Inhibitor_G39P PF11417.8 VBB32009.1 - 0.17 12.5 0.9 0.53 10.9 0.1 2.1 1 1 1 2 2 2 0 Loader and inhibitor of phage G40P MFS_1 PF07690.16 VBB32010.1 - 2.2e-12 46.6 47.5 7.6e-10 38.2 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L7Ae PF01248.26 VBB32011.1 - 3.8e-12 45.8 0.1 6.5e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.6 VBB32011.1 - 0.0098 16.1 0.6 0.015 15.5 0.6 1.3 1 0 0 1 1 1 1 Heavy-metal resistance p450 PF00067.22 VBB32012.1 - 4e-24 85.2 0.1 4.2e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kunitz_BPTI PF00014.23 VBB32013.1 - 1.9e-12 47.2 5.1 4.8e-12 45.9 5.1 1.7 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 VBB32013.1 - 6.2e-05 23.3 3.9 6.2e-05 23.3 3.9 2.7 2 1 0 2 2 2 1 Lustrin, cysteine-rich repeated domain Pil1 PF13805.6 VBB32014.1 - 0.0067 15.9 0.8 0.0098 15.4 0.8 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 UPF0242 PF06785.11 VBB32014.1 - 0.016 15.3 1.4 0.026 14.7 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4710 PF15828.5 VBB32014.1 - 0.079 13.1 1.7 0.19 11.9 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) HR1 PF02185.16 VBB32014.1 - 0.28 11.3 7.2 0.13 12.3 3.9 2.2 2 1 0 2 2 2 0 Hr1 repeat DZR PF12773.7 VBB32014.1 - 0.3 11.1 2.9 0.89 9.6 2.9 1.8 1 0 0 1 1 1 0 Double zinc ribbon Ribul_P_3_epim PF00834.19 VBB32015.1 - 5.5e-64 215.2 0.1 6.3e-64 215.0 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 VBB32015.1 - 0.0009 19.1 0.0 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 VBB32015.1 - 0.0075 15.8 0.1 0.22 11.0 0.1 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein Cation_ATPase_C PF00689.21 VBB32016.1 - 1.9e-45 154.8 7.8 1e-44 152.5 5.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 VBB32016.1 - 2.9e-15 57.1 0.0 6.4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 VBB32016.1 - 9.3e-06 25.6 1.7 1.2e-05 25.2 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB32016.1 - 4.1e-05 24.1 0.0 0.0004 20.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF423 PF04241.15 VBB32017.1 - 3.1e-19 69.0 0.0 5e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) SepSecS PF05889.13 VBB32018.1 - 1.2e-125 419.3 0.0 1.5e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 VBB32018.1 - 0.00036 19.9 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase_Tyr PF07714.17 VBB32019.1 - 5.5e-48 163.5 0.1 7.7e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S7 PF00177.21 VBB32019.1 - 1.7e-34 118.6 0.5 2.8e-34 117.9 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pkinase PF00069.25 VBB32019.1 - 5.3e-25 88.3 0.0 7.9e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 VBB32019.1 - 0.0094 15.3 0.2 0.06 12.7 0.2 2.1 1 1 0 1 1 1 1 Kinase-like tRNA-synt_1d PF00750.19 VBB32021.1 - 2.5e-134 447.7 0.1 4.2e-134 446.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) RNA_pol_Rpb8 PF03870.15 VBB32021.1 - 1.4e-43 148.4 0.0 5.3e-43 146.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Arg_tRNA_synt_N PF03485.16 VBB32021.1 - 1.2e-21 77.1 0.2 4.6e-21 75.2 0.1 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.15 VBB32021.1 - 1.8e-18 66.9 0.9 4.7e-18 65.5 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 VBB32021.1 - 0.02 14.2 0.0 0.052 12.9 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain WD40 PF00400.32 VBB32022.1 - 8.6e-17 61.2 3.0 0.015 16.1 0.0 8.5 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB32022.1 - 1.3e-09 38.2 0.2 0.0048 17.2 0.0 6.8 7 1 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain RNase_PH PF01138.21 VBB32023.1 - 8.4e-20 71.6 0.0 2.1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Prefoldin PF02996.17 VBB32023.1 - 1.4e-17 63.7 0.3 3.2e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 Prefoldin subunit RNase_PH_C PF03725.15 VBB32023.1 - 5.5e-14 51.9 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 GWT1 PF06423.12 VBB32025.1 - 1.7e-24 86.7 14.1 8.4e-23 81.2 7.5 5.2 3 2 0 4 4 4 2 GWT1 DUF373 PF04123.13 VBB32025.1 - 0.0022 17.5 0.4 0.0022 17.5 0.4 4.2 2 1 0 3 3 3 2 Domain of unknown function (DUF373) AAA PF00004.29 VBB32026.1 - 6.9e-40 136.5 0.0 1.6e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB32026.1 - 1.1e-08 34.8 0.1 2.7e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 VBB32026.1 - 0.00011 22.5 0.1 0.0059 16.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB32026.1 - 0.00049 20.5 0.1 0.0053 17.1 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 VBB32026.1 - 0.00053 20.0 0.0 0.002 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 VBB32026.1 - 0.0045 16.2 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 VBB32026.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 VBB32026.1 - 0.0086 15.4 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_2 PF07724.14 VBB32026.1 - 0.014 15.5 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 VBB32026.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 VBB32026.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 VBB32026.1 - 0.022 14.3 0.0 0.053 13.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 VBB32026.1 - 0.029 14.9 0.0 0.079 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB32026.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 VBB32026.1 - 0.044 13.5 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 VBB32026.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 VBB32026.1 - 0.092 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 VBB32026.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 VBB32026.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 VBB32026.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 VBB32026.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 VBB32026.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 VBB32028.1 - 1.2e-91 304.0 0.0 3.6e-46 156.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB32028.1 - 1e-26 92.5 3.6 4.4e-13 48.8 0.6 3.0 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 VBB32028.1 - 3e-21 75.4 1.1 7.1e-21 74.2 1.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 VBB32028.1 - 2.5e-13 50.8 0.1 0.00018 21.9 0.1 4.3 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 VBB32028.1 - 2.9e-13 49.9 0.0 2.6e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 VBB32028.1 - 3.7e-11 43.2 0.0 8.7e-05 22.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 VBB32028.1 - 6.2e-11 41.9 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 VBB32028.1 - 3.8e-10 40.1 0.0 0.00016 21.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 VBB32028.1 - 1.1e-09 38.6 0.0 0.00054 20.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 VBB32028.1 - 7.8e-09 35.9 0.1 0.038 14.3 0.0 3.8 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 VBB32028.1 - 2e-08 33.9 0.0 0.0019 17.4 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 VBB32028.1 - 9.2e-08 32.7 0.0 0.022 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 VBB32028.1 - 2.4e-07 30.6 0.1 1.5e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 VBB32028.1 - 3.6e-07 30.1 0.0 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 VBB32028.1 - 4.9e-07 29.3 0.1 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 VBB32028.1 - 5.3e-07 30.0 0.0 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Parvo_NS1 PF01057.17 VBB32028.1 - 1.6e-06 27.4 0.1 0.018 14.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 VBB32028.1 - 4.6e-06 27.0 0.1 0.15 12.3 0.0 3.2 3 1 1 4 4 2 2 AAA domain ATPase PF06745.13 VBB32028.1 - 5.5e-06 25.9 0.0 0.42 9.9 0.0 3.4 3 0 0 3 3 3 2 KaiC ABC_tran PF00005.27 VBB32028.1 - 6.6e-06 26.7 0.0 0.0089 16.5 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 VBB32028.1 - 1.2e-05 25.0 0.6 1.1 8.9 0.0 3.5 2 2 0 3 3 3 2 AAA domain UFD1 PF03152.14 VBB32028.1 - 1.7e-05 24.4 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_7 PF12775.7 VBB32028.1 - 2.2e-05 24.0 0.0 0.15 11.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 VBB32028.1 - 2.3e-05 24.4 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 VBB32028.1 - 3.7e-05 23.7 0.2 0.16 11.9 0.0 3.5 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.18 VBB32028.1 - 7e-05 22.8 0.0 0.34 10.7 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_24 PF13479.6 VBB32028.1 - 7e-05 22.6 0.1 0.12 12.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 VBB32028.1 - 9.8e-05 22.3 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 VBB32028.1 - 0.00011 22.2 0.1 0.61 10.0 0.0 3.4 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 VBB32028.1 - 0.00013 21.7 0.0 0.6 9.8 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 VBB32028.1 - 0.00016 22.1 0.4 1 9.8 0.0 3.3 4 0 0 4 4 2 2 AAA domain NB-ARC PF00931.22 VBB32028.1 - 0.00053 19.3 0.0 0.33 10.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain PhoH PF02562.16 VBB32028.1 - 0.00079 18.9 0.1 1.5 8.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 VBB32028.1 - 0.0011 19.0 0.0 0.88 9.7 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 VBB32028.1 - 0.0011 18.2 0.0 0.87 8.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.11 VBB32028.1 - 0.0014 18.5 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 VBB32028.1 - 0.0015 17.9 0.0 0.53 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 VBB32028.1 - 0.002 17.4 0.0 1.9 7.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 VBB32028.1 - 0.002 17.9 0.0 0.057 13.2 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 VBB32028.1 - 0.0022 18.0 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 VBB32028.1 - 0.0023 17.8 0.3 2.3 7.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 VBB32028.1 - 0.0052 16.7 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 VBB32028.1 - 0.0083 16.5 1.3 3.5 8.0 0.2 3.0 3 1 0 3 3 2 1 AAA domain Cytidylate_kin2 PF13189.6 VBB32028.1 - 0.013 15.6 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_30 PF13604.6 VBB32028.1 - 0.028 14.2 0.1 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 VBB32028.1 - 0.05 13.5 0.3 9.2 6.1 0.0 3.4 4 1 1 5 5 3 0 NTPase KAP_NTPase PF07693.14 VBB32028.1 - 0.051 12.8 0.0 3 7.0 0.0 2.8 2 2 0 3 3 3 0 KAP family P-loop domain Cytidylate_kin PF02224.18 VBB32028.1 - 0.062 13.0 0.0 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 VBB32028.1 - 0.1 12.7 0.5 15 5.7 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase TniB PF05621.11 VBB32028.1 - 0.12 11.8 0.0 13 5.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 VBB32028.1 - 0.13 12.7 0.3 17 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Troponin PF00992.20 VBB32029.1 - 0.00065 20.0 4.9 0.00065 20.0 4.9 2.1 2 0 0 2 2 2 1 Troponin DUF4795 PF16043.5 VBB32029.1 - 0.0069 16.0 1.9 0.019 14.6 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) DUF1794 PF08768.11 VBB32030.1 - 6.8e-23 81.3 0.0 8.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Adaptin_N PF01602.20 VBB32031.1 - 2.1e-148 495.2 6.5 2.7e-148 494.8 6.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 VBB32031.1 - 5.2e-41 139.4 0.0 1.7e-40 137.7 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 VBB32031.1 - 1.4e-12 47.8 0.0 3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 VBB32031.1 - 2.5e-08 34.1 0.9 6.9e-07 29.4 0.0 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 VBB32031.1 - 0.00017 21.9 1.4 0.24 11.8 0.1 3.9 3 0 0 3 3 3 1 HEAT repeats B2-adapt-app_C PF09066.10 VBB32031.1 - 0.0013 18.8 0.4 0.029 14.5 0.0 2.6 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 VBB32031.1 - 0.003 17.7 1.8 20 5.8 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Spec3 PF15795.5 VBB32033.1 - 6e-30 103.6 6.3 8.8e-30 103.1 6.3 1.2 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein PulG PF11773.8 VBB32033.1 - 0.033 14.0 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin SLC12 PF03522.15 VBB32034.1 - 4.9e-28 98.3 13.2 8.4e-26 91.0 13.2 2.7 1 1 0 1 1 1 1 Solute carrier family 12 CENP-B_dimeris PF09026.10 VBB32034.1 - 0.022 15.1 2.3 0.041 14.3 2.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 VBB32034.1 - 0.22 11.4 5.4 0.31 10.9 5.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.25 VBB32035.1 - 7.3e-34 117.3 0.0 1.1e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32035.1 - 1.4e-18 67.2 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB32035.1 - 0.0026 16.6 0.0 0.0068 15.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 VBB32035.1 - 0.0043 17.0 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB32035.1 - 0.12 11.6 0.0 0.3 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 VBB32035.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsbL PF02419.17 VBB32036.1 - 0.49 10.4 3.7 0.9 9.6 3.7 1.4 1 0 0 1 1 1 0 PsbL protein DUF4207 PF13904.6 VBB32037.1 - 0.00023 21.0 35.7 0.00023 21.0 35.7 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4207) MADF_DNA_bdg PF10545.9 VBB32040.1 - 9.2e-16 57.9 0.1 1.3e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB32040.1 - 6e-09 36.2 0.1 8.1e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 VBB32040.1 - 1.3 9.3 4.3 2.9 8.1 4.3 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Cyclin_N PF00134.23 VBB32042.1 - 1.7e-11 44.0 0.5 3.6e-10 39.7 0.1 2.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 VBB32042.1 - 2.4e-09 37.5 0.0 5.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin C-terminal domain zf_CCCH_4 PF18345.1 VBB32042.1 - 5.6e-07 29.4 3.4 5.6e-07 29.4 3.4 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 VBB32042.1 - 9.8e-06 25.4 0.7 9.8e-06 25.4 0.7 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 VBB32042.1 - 0.00041 21.0 0.1 0.00041 21.0 0.1 2.4 3 0 0 3 3 3 1 Torus domain zf-CCCH_4 PF18044.1 VBB32042.1 - 0.0094 15.7 3.9 0.0094 15.7 3.9 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger Cyclin_C PF02984.19 VBB32042.1 - 0.0094 16.0 0.1 0.096 12.8 0.0 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain Filamin PF00630.19 VBB32043.1 - 2.1e-46 157.0 0.2 2.1e-10 41.3 0.0 5.4 5 0 0 5 5 5 5 Filamin/ABP280 repeat DUF5060 PF16586.5 VBB32043.1 - 1.1e-05 25.7 0.0 1.2 9.6 0.0 4.0 4 1 0 4 4 4 2 Domain of unknown function (DUF5060) Invasin_D3 PF09134.10 VBB32043.1 - 0.00087 19.5 0.1 28 5.1 0.0 4.9 6 1 0 6 6 6 1 Invasin, domain 3 DUF3086 PF11285.8 VBB32043.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) UPF0086 PF01868.16 VBB32043.1 - 0.13 12.2 0.0 2.2 8.2 0.0 2.7 1 1 0 1 1 1 0 Domain of unknown function UPF0086 Y_phosphatase PF00102.27 VBB32046.1 - 3e-59 200.5 0.5 3.8e-59 200.1 0.5 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB32046.1 - 0.0038 17.1 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB32046.1 - 0.0046 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB32046.1 - 0.045 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Las1 PF04031.13 VBB32049.1 - 1.2e-14 54.7 0.5 1.2e-14 54.7 0.5 2.4 2 1 0 2 2 2 1 Las1-like SUIM_assoc PF16619.5 VBB32049.1 - 0.0062 16.6 0.3 0.029 14.5 0.0 2.2 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 YusW PF14039.6 VBB32049.1 - 0.013 16.0 0.2 0.013 16.0 0.2 2.4 2 1 0 2 2 2 0 YusW-like protein MCM PF00493.23 VBB32050.1 - 7.1e-101 336.0 0.0 1.2e-100 335.2 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 VBB32050.1 - 2.3e-35 121.2 0.1 4.1e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 VBB32050.1 - 1.2e-26 93.0 0.8 3.4e-26 91.5 0.8 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 VBB32050.1 - 9.6e-12 45.4 0.1 3.5e-11 43.6 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 VBB32050.1 - 1.3e-10 41.7 41.5 1.6e-10 41.5 37.3 3.0 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 VBB32050.1 - 1.4e-08 34.4 0.0 4.7e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB32050.1 - 5.2e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 VBB32050.1 - 2.9e-05 23.9 0.0 0.00046 20.0 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 VBB32050.1 - 0.01 15.5 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 VBB32050.1 - 0.016 15.6 0.0 0.074 13.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF823 PF05689.11 VBB32050.1 - 0.038 13.7 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) AAA_lid_2 PF17863.1 VBB32050.1 - 0.11 12.3 3.5 0.16 11.8 0.2 2.9 3 0 0 3 3 3 0 AAA lid domain Zn-ribbon_8 PF09723.10 VBB32050.1 - 0.26 11.4 1.3 0.71 10.0 1.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Motile_Sperm PF00635.26 VBB32051.1 - 3.1e-20 72.0 0.0 3.1e-20 72.0 0.0 2.9 3 1 0 3 3 3 1 MSP (Major sperm protein) domain PapD_N PF00345.20 VBB32051.1 - 0.00043 20.2 0.0 0.002 18.0 0.0 2.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain ASH PF15780.5 VBB32051.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Smg8_Smg9 PF10220.9 VBB32051.1 - 0.27 9.5 17.5 0.3 9.4 17.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 zf-C2H2_jaz PF12171.8 VBB32053.1 - 0.014 15.7 0.0 0.038 14.3 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding UPF0547 PF10571.9 VBB32053.1 - 0.028 14.5 0.9 0.078 13.1 0.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 BLOC1_2 PF10046.9 VBB32054.1 - 2.4e-30 104.7 3.2 2.4e-30 104.7 3.2 2.3 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.13 VBB32054.1 - 0.003 17.8 0.9 0.003 17.8 0.9 2.8 3 1 0 3 3 3 1 Tho complex subunit 7 DUF1664 PF07889.12 VBB32054.1 - 0.013 15.5 0.6 0.076 13.1 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF220 PF02713.14 VBB32054.1 - 0.028 14.5 0.2 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF220 Med9 PF07544.13 VBB32054.1 - 0.042 14.0 1.4 0.41 10.8 0.5 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SdpA PF17418.2 VBB32054.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Sporulation delaying protein SdpA UPF0449 PF15136.6 VBB32054.1 - 8.9 6.8 7.7 7.4 7.1 1.6 3.4 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 STAR_dimer PF16544.5 VBB32056.1 - 4.5e-08 32.5 0.9 9.5e-08 31.5 0.9 1.6 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 VBB32056.1 - 8.8e-06 25.5 0.4 2e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 KH domain DEAD PF00270.29 VBB32058.1 - 9.5e-35 119.9 0.0 1.7e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB32058.1 - 4.9e-21 75.2 0.1 5e-20 71.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB32058.1 - 1.6e-09 38.0 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 VBB32058.1 - 0.00037 20.8 0.0 0.00096 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 VBB32058.1 - 0.0053 16.5 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 VBB32058.1 - 0.0086 16.5 0.1 0.095 13.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 VBB32058.1 - 0.037 14.4 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 VBB32058.1 - 0.05 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.6 VBB32058.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M20 PF01546.28 VBB32059.1 - 2.9e-32 112.1 0.0 4.9e-32 111.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 VBB32059.1 - 1.6e-10 40.8 0.0 2.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Sterile PF03015.19 VBB32060.1 - 1.4e-28 99.0 0.4 2.7e-28 98.0 0.4 1.5 1 0 0 1 1 1 1 Male sterility protein NAD_binding_4 PF07993.12 VBB32060.1 - 2.7e-13 49.7 0.1 3.6e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein LRR_8 PF13855.6 VBB32061.1 - 2.1e-16 59.4 27.3 9.3e-08 31.7 2.4 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 VBB32061.1 - 1.7e-14 53.6 12.4 3e-05 24.3 0.6 4.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB32061.1 - 4.4e-06 26.5 12.6 5.4 8.0 0.0 6.5 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 VBB32061.1 - 0.058 12.9 2.0 0.1 12.1 2.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 VBB32061.1 - 0.093 12.8 17.5 0.35 11.0 0.2 5.3 6 0 0 6 6 6 0 Leucine Rich repeat EMC1_C PF07774.13 VBB32062.1 - 9.4e-67 224.8 0.0 1.5e-66 224.1 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 VBB32062.1 - 0.019 14.8 0.1 11 6.1 0.0 3.2 2 0 0 2 2 2 0 PQQ enzyme repeat HSP20 PF00011.21 VBB32064.1 - 4.7e-12 45.9 0.2 5.9e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Band_7 PF01145.25 VBB32065.1 - 2.6e-31 109.0 2.3 3.3e-31 108.7 2.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 VBB32065.1 - 0.00095 18.9 0.2 0.0014 18.4 0.2 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family RRM_1 PF00076.22 VBB32066.1 - 9.3e-33 111.9 0.0 1.9e-17 62.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB32066.1 - 1.3e-08 34.8 0.0 0.00035 20.6 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 VBB32066.1 - 0.00093 19.3 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB32066.1 - 0.0028 17.6 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 VBB32066.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_1 PF00076.22 VBB32067.1 - 3.9e-33 113.1 0.0 4.1e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 VBB32067.1 - 3e-08 33.6 0.0 0.0042 17.1 0.1 2.1 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 VBB32067.1 - 0.0058 16.7 0.0 0.022 14.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB32067.1 - 0.1 12.6 0.0 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 VBB32067.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif AAA_2 PF07724.14 VBB32069.1 - 2.6e-37 128.6 0.0 5.3e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 VBB32069.1 - 2.4e-12 47.4 0.0 5.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 VBB32069.1 - 3.5e-08 33.4 0.1 1.6e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 VBB32069.1 - 2.5e-05 24.3 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 VBB32069.1 - 4.8e-05 23.2 0.2 0.00019 21.3 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 VBB32069.1 - 5.2e-05 22.4 0.1 9.8e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 VBB32069.1 - 6e-05 22.5 0.4 0.013 14.9 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 VBB32069.1 - 9.9e-05 22.1 0.1 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 VBB32069.1 - 0.00075 19.8 0.1 0.0079 16.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 VBB32069.1 - 0.0009 19.3 0.0 0.0091 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 VBB32069.1 - 0.0017 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 VBB32069.1 - 0.0021 18.6 0.0 0.0065 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB32069.1 - 0.003 18.0 0.2 0.029 14.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 VBB32069.1 - 0.0065 16.4 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 VBB32069.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 VBB32069.1 - 0.035 14.0 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 VBB32069.1 - 0.044 13.5 0.1 0.13 12.0 0.1 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 VBB32069.1 - 0.055 14.0 0.2 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 VBB32069.1 - 0.058 13.8 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 VBB32069.1 - 0.076 12.7 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 VBB32069.1 - 0.12 12.2 0.8 1 9.3 0.2 2.6 2 1 0 2 2 2 0 NACHT domain TUDOR PF00567.24 VBB32070.1 - 1.7e-12 47.4 0.9 3.8e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 Tudor domain Birna_VP2 PF01766.17 VBB32070.1 - 0.097 11.6 0.5 0.24 10.3 0.1 1.7 2 0 0 2 2 2 0 Birnavirus VP2 protein SMN PF06003.12 VBB32070.1 - 0.51 9.6 4.6 13 5.0 0.0 3.2 3 1 1 4 4 4 0 Survival motor neuron protein (SMN) Ig_3 PF13927.6 VBB32071.1 - 4.4e-47 158.6 1.7 2.5e-11 44.0 0.2 5.5 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 VBB32071.1 - 1.1e-43 147.1 3.6 3e-12 46.4 0.0 6.0 5 2 0 5 5 5 4 Immunoglobulin I-set domain ig PF00047.25 VBB32071.1 - 6.6e-33 112.8 0.9 1.3e-06 28.5 0.0 5.9 5 1 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 VBB32071.1 - 1.9e-23 82.6 4.8 5.1e-07 29.9 0.1 5.6 7 0 0 7 7 7 4 Immunoglobulin domain V-set PF07686.17 VBB32071.1 - 1.8e-15 57.0 4.4 2.1e-05 24.7 0.0 6.7 4 4 2 6 6 6 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB32071.1 - 1.1e-12 47.9 2.5 7.4e-06 25.9 0.0 6.4 5 2 1 6 6 6 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 VBB32071.1 - 6.3e-09 36.1 3.2 0.011 16.0 0.1 5.0 5 2 0 5 5 4 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 VBB32071.1 - 4.5e-06 26.8 0.4 0.45 10.8 0.0 5.3 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 VBB32071.1 - 1.5e-05 25.3 0.1 1.4 9.4 0.0 4.8 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 VBB32071.1 - 0.0022 18.0 0.0 7.9 6.6 0.0 3.8 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB32071.1 - 0.016 15.2 0.0 11 6.1 0.0 3.8 4 0 0 4 4 4 0 C17orf99 Ig domain Ig_6 PF18452.1 VBB32071.1 - 0.061 12.9 0.0 16 5.1 0.0 3.3 4 0 0 4 4 4 0 Immunoglobulin domain COX6B PF02297.17 VBB32072.1 - 2.2e-13 50.2 0.4 4.3e-13 49.3 0.4 1.5 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Ras PF00071.22 VBB32073.1 - 2.8e-12 46.5 0.0 2.9e-08 33.5 0.0 2.2 1 1 1 2 2 2 2 Ras family Roc PF08477.13 VBB32073.1 - 1.8e-06 28.1 0.1 9.2e-06 25.9 0.0 1.8 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB32073.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Enolase_C PF00113.22 VBB32074.1 - 8.8e-148 491.3 2.5 2.6e-147 489.8 2.5 1.7 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 VBB32074.1 - 2.6e-56 189.4 0.0 4.9e-56 188.5 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 VBB32074.1 - 8.4e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 VBB32074.1 - 6.5e-05 22.2 0.5 0.00021 20.6 0.5 1.8 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF229 PF02995.17 VBB32075.1 - 1.6e-70 238.1 0.2 1.9e-70 237.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 VBB32075.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase eIF-3c_N PF05470.12 VBB32076.1 - 9.9e-201 668.1 47.7 8e-200 665.1 47.7 2.2 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 VBB32076.1 - 7.4e-16 58.6 2.0 1.5e-15 57.6 0.4 2.4 2 0 0 2 2 2 1 PCI domain Cir_Bir_Yir PF06022.11 VBB32076.1 - 0.0016 18.0 0.6 0.0046 16.5 0.6 1.8 1 0 0 1 1 1 1 Plasmodium variant antigen protein Cir/Yir/Bir CDC45 PF02724.14 VBB32077.1 - 6.1 5.0 10.8 6.4 4.9 10.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DSPc PF00782.20 VBB32079.1 - 5e-32 110.5 0.1 7.5e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB32079.1 - 0.00021 21.0 0.1 0.0004 20.0 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 VBB32079.1 - 0.00051 20.3 0.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 VBB32079.1 - 0.034 14.3 0.2 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Kringle PF00051.18 VBB32081.1 - 3.6e-08 33.6 2.4 3.6e-08 33.6 2.4 2.5 2 1 0 2 2 2 1 Kringle domain Myosin_tail_1 PF01576.19 VBB32082.1 - 2.8e-197 657.9 266.2 3.2e-197 657.7 266.2 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 VBB32082.1 - 1.1e-92 311.5 0.0 1.1e-92 311.5 0.0 3.5 2 1 1 3 3 3 1 Myosin head (motor domain) IQ PF00612.27 VBB32082.1 - 0.0023 17.6 1.0 0.009 15.7 1.0 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif HTH_IclR PF09339.10 VBB32082.1 - 2.5 8.0 7.8 0.15 11.9 0.5 2.8 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF5126 PF17166.4 VBB32082.1 - 4.9 7.1 6.6 0.46 10.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5126) BACK PF07707.15 VBB32084.1 - 7e-10 38.9 0.1 7.8e-09 35.6 0.0 2.2 1 1 1 2 2 2 1 BTB And C-terminal Kelch Pox_EPC_I2-L1 PF12575.8 VBB32084.1 - 0.092 13.0 0.3 0.87 9.9 0.0 2.5 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Dor1 PF04124.12 VBB32085.1 - 6.3e-73 245.4 8.0 6.3e-73 245.4 8.0 1.5 2 0 0 2 2 2 1 Dor1-like family Laminin_II PF06009.12 VBB32085.1 - 0.064 13.3 1.1 0.22 11.5 1.1 2.0 1 1 0 1 1 1 0 Laminin Domain II Syntaxin-6_N PF09177.11 VBB32085.1 - 0.23 12.1 1.6 1.7 9.2 1.1 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_L29 PF00831.23 VBB32085.1 - 7.1 6.7 6.8 23 5.0 0.7 3.5 4 0 0 4 4 4 0 Ribosomal L29 protein WW PF00397.26 VBB32086.1 - 1.5e-10 40.9 1.0 1.5e-10 40.9 1.0 1.7 2 0 0 2 2 2 1 WW domain PIN_4 PF13638.6 VBB32086.1 - 5e-06 26.8 0.3 3.2e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 PIN domain Collagen PF01391.18 VBB32087.1 - 3.2e-07 30.0 14.9 3.8e-07 29.7 14.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 VBB32088.1 - 9.4e-66 221.9 0.0 1.3e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32088.1 - 2.2e-48 164.8 0.0 3.1e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 VBB32088.1 - 1.2e-17 63.7 2.4 2.3e-17 62.8 2.4 1.5 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 VBB32088.1 - 2.3e-09 36.6 0.0 3.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB32088.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abi_2 PF07751.11 VBB32088.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Abi-like protein Phage_Mu_Gam PF07352.12 VBB32088.1 - 0.14 12.0 0.6 0.26 11.2 0.6 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Haspin_kinase PF12330.8 VBB32088.1 - 0.16 10.9 0.3 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain DUF3752 PF12572.8 VBB32089.1 - 6.1e-13 49.6 0.2 6.1e-13 49.6 0.2 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) HSP20 PF00011.21 VBB32090.1 - 3.1e-15 56.2 0.1 3.1e-15 56.2 0.1 1.8 2 0 0 2 2 2 1 Hsp20/alpha crystallin family zf-C4 PF00105.18 VBB32091.1 - 2.1e-14 53.7 4.5 4.5e-14 52.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB32091.1 - 8.5e-09 35.3 0.2 1.8e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CBM_21 PF03370.13 VBB32092.1 - 2.8e-28 98.3 0.2 5.5e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 VBB32092.1 - 3.5e-11 43.5 0.2 3.5e-11 43.5 0.2 1.9 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) AHH PF14412.6 VBB32093.1 - 0.041 13.9 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Neur_chan_LBD PF02931.23 VBB32094.1 - 7.7e-43 146.4 1.2 1.1e-42 145.9 1.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB32094.1 - 8.6e-16 58.7 1.0 8.6e-16 58.7 1.0 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Lactamase_B PF00753.27 VBB32095.1 - 1.7e-12 47.8 2.4 4.7e-12 46.3 2.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB32095.1 - 9.5e-05 22.0 0.2 0.00016 21.2 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Profilin PF00235.19 VBB32096.1 - 3.4e-40 137.2 0.4 3.7e-40 137.1 0.4 1.0 1 0 0 1 1 1 1 Profilin SWIM PF04434.17 VBB32097.1 - 0.0024 17.5 9.1 0.0034 17.0 7.7 2.1 2 0 0 2 2 2 1 SWIM zinc finger NEMP PF10225.9 VBB32098.1 - 1.7e-69 234.3 7.5 2.6e-69 233.7 7.5 1.3 1 0 0 1 1 1 1 NEMP family G6PD_C PF02781.16 VBB32099.1 - 1.5e-113 378.8 0.0 1.9e-113 378.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 VBB32099.1 - 1.6e-58 198.2 0.0 4.7e-58 196.7 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain AAA_lid_11 PF18198.1 VBB32100.1 - 0.076 12.8 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Ion_trans PF00520.31 VBB32101.1 - 3e-20 72.5 2.2 3.4e-20 72.3 2.2 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 VBB32101.1 - 2.6e-13 49.7 6.2 3.9e-13 49.2 6.2 1.2 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 VBB32101.1 - 0.0003 20.7 1.2 0.0005 19.9 0.9 1.4 1 1 0 1 1 1 1 Ligand-gated ion channel DUF4212 PF13937.6 VBB32101.1 - 0.025 14.9 2.0 0.045 14.1 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DctQ PF04290.12 VBB32101.1 - 0.056 13.4 0.8 0.056 13.4 0.8 1.6 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Tetraspanin PF00335.20 VBB32101.1 - 1.1 8.9 3.8 2.9 7.5 3.9 1.7 1 1 0 1 1 1 0 Tetraspanin family PLAT PF01477.23 VBB32102.1 - 4.1e-15 56.4 0.1 1.3e-14 54.8 0.1 1.9 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 VBB32102.1 - 0.00018 21.4 0.0 0.00068 19.5 0.0 2.0 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) zf-H2C2_5 PF13909.6 VBB32102.1 - 0.0006 19.5 0.2 0.0006 19.5 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 VBB32102.1 - 0.00088 19.9 45.9 0.34 11.9 0.8 7.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB32102.1 - 0.0062 16.9 0.3 0.0062 16.9 0.3 6.9 6 0 0 6 6 6 2 Zinc finger, C2H2 type PDZ PF00595.24 VBB32103.1 - 2.7e-10 40.4 0.1 1.4e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB32103.1 - 1.2e-09 37.9 0.2 4.7e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 VBB32103.1 - 2.1e-09 37.6 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 VBB32103.1 - 0.00043 20.2 0.0 0.92 9.5 0.0 2.7 2 1 0 2 2 2 2 Tricorn protease PDZ domain SP2 PF03014.14 VBB32103.1 - 0.13 10.6 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 Ribosomal_L16 PF00252.18 VBB32104.1 - 3.8e-42 143.4 0.1 4.7e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pkinase PF00069.25 VBB32105.1 - 9.2e-25 87.5 0.0 1.7e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32105.1 - 1.5e-10 40.8 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PI3_PI4_kinase PF00454.27 VBB32106.1 - 3.6e-43 148.2 0.3 5.8e-29 101.7 0.2 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 VBB32106.1 - 0.0048 16.3 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3Ka PF00613.20 VBB32107.1 - 1.1e-23 83.6 0.1 2.2e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Y_phosphatase PF00102.27 VBB32108.1 - 6.8e-59 199.3 0.1 6.8e-59 199.3 0.1 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 VBB32108.1 - 0.00081 19.5 1.2 0.35 11.0 0.0 3.4 3 0 0 3 3 3 2 Inositol hexakisphosphate DSPc PF00782.20 VBB32108.1 - 0.0043 16.9 0.4 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB32108.1 - 0.017 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Arc_PepC_II PF06847.11 VBB32109.1 - 0.11 13.1 0.3 0.58 10.7 0.2 2.2 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Y_phosphatase PF00102.27 VBB32111.1 - 3.1e-41 141.5 0.2 3.6e-41 141.3 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB32111.1 - 0.00016 21.8 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 VBB32111.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 VBB32111.1 - 0.0074 16.4 0.3 0.017 15.2 0.0 1.8 2 1 1 3 3 3 1 Inositol hexakisphosphate Ion_trans_2 PF07885.16 VBB32112.1 - 2.4e-25 88.3 30.6 3.2e-13 49.5 13.3 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB32112.1 - 0.0025 17.1 14.7 0.26 10.5 9.9 2.5 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 VBB32112.1 - 0.25 11.2 1.9 0.7 9.7 0.1 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel DUF3464 PF11947.8 VBB32112.1 - 0.38 10.5 5.7 2.4 7.9 0.0 3.2 2 1 1 3 3 3 0 Photosynthesis affected mutant 68 Collagen PF01391.18 VBB32115.1 - 2.6e-24 84.7 75.9 7.9e-11 41.6 27.2 3.6 3 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32115.1 - 6.9e-17 61.3 0.4 9.2e-17 60.8 0.4 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Romo1 PF10247.9 VBB32116.1 - 5.9e-22 77.8 16.5 6.8e-22 77.6 16.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 VBB32116.1 - 4.4e-05 23.8 8.7 5e-05 23.7 8.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rotamase PF00639.21 VBB32117.1 - 6.6e-22 78.3 0.6 1.3e-21 77.3 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 VBB32117.1 - 2.4e-17 63.6 0.0 4.6e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 VBB32117.1 - 7.5e-12 45.1 0.6 1.4e-11 44.2 0.6 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 VBB32117.1 - 2.8e-06 28.2 0.0 3.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 PPIC-type PPIASE domain Glyco_hyd_101C PF17451.2 VBB32117.1 - 0.095 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 VBB32117.1 - 0.096 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 PQQ enzyme repeat EntA_Immun PF08951.10 VBB32117.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Enterocin A Immunity FAM184 PF15665.5 VBB32117.1 - 0.13 12.0 2.7 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DAO PF01266.24 VBB32118.1 - 9.6e-43 147.1 0.0 1.3e-42 146.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NTP_transferase PF00483.23 VBB32119.1 - 1.9e-50 171.8 0.0 3e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 VBB32119.1 - 1e-11 44.1 11.9 1.1e-06 28.2 0.6 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 VBB32119.1 - 9.9e-11 42.3 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 VBB32119.1 - 0.046 13.5 0.9 0.046 13.5 0.9 3.2 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 VBB32119.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase SWIM PF04434.17 VBB32120.1 - 0.067 12.9 1.6 0.41 10.4 0.2 2.1 2 0 0 2 2 2 0 SWIM zinc finger UQ_con PF00179.26 VBB32121.1 - 5.5e-42 142.7 0.0 1.2e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hint PF01079.20 VBB32121.1 - 1.6e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 VBB32121.1 - 0.014 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Hint domain zf-C4 PF00105.18 VBB32123.1 - 3.5e-29 101.0 15.6 3.5e-29 101.0 15.6 2.1 2 1 1 3 3 3 1 Zinc finger, C4 type (two domains) PDEase_I PF00233.19 VBB32124.1 - 2.2e-57 194.6 3.7 3.5e-57 193.9 3.7 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Methyltransf_23 PF13489.6 VBB32124.1 - 3.7e-17 62.6 0.0 4.5e-16 59.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB32124.1 - 1.4e-14 54.5 0.0 7e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB32124.1 - 4.7e-14 52.9 0.0 4e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB32124.1 - 2.1e-10 41.1 0.0 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB32124.1 - 6.9e-09 35.7 0.1 1.8e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB32124.1 - 0.00019 20.9 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 VBB32124.1 - 0.00049 19.7 0.0 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain CheR PF01739.18 VBB32124.1 - 0.00096 18.7 0.0 0.08 12.4 0.0 2.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.11 VBB32124.1 - 0.0024 17.5 0.0 0.0058 16.3 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 VBB32124.1 - 0.014 16.4 0.0 0.061 14.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 VBB32124.1 - 0.015 14.5 0.1 0.17 11.0 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family PrmA PF06325.13 VBB32124.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) YajC PF02699.15 VBB32124.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Opiods_neuropep PF01160.18 VBB32124.1 - 0.16 12.1 0.6 0.43 10.7 0.6 1.7 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Homeodomain PF00046.29 VBB32126.1 - 1.1e-18 66.8 8.1 1.1e-18 66.8 8.1 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB32126.1 - 0.00033 20.5 0.8 0.00033 20.5 0.8 2.0 2 0 0 2 2 2 1 Homeobox KN domain T7SS_ESX_EspC PF10824.8 VBB32126.1 - 0.046 14.2 6.1 0.18 12.3 0.5 2.4 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm K_channel_TID PF07941.11 VBB32126.1 - 10 6.7 12.9 10 6.7 5.8 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain FoP_duplication PF13865.6 VBB32128.1 - 8.4e-08 32.7 2.8 8.4e-08 32.7 2.8 2.3 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 VBB32128.1 - 0.00041 20.1 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP PF00230.20 VBB32129.1 - 2.3e-08 34.0 14.4 3.2e-08 33.6 14.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein CBS PF00571.28 VBB32130.1 - 3.9e-21 75.3 6.0 5.1e-06 26.8 0.1 4.4 4 0 0 4 4 4 4 CBS domain C12orf66_like PF09404.10 VBB32132.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like EF-hand_1 PF00036.32 VBB32133.1 - 1.1e-17 62.2 3.7 9.3e-09 34.2 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 VBB32133.1 - 1.2e-13 51.2 0.3 1.7e-13 50.8 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB32133.1 - 6.5e-13 47.5 1.6 7.6e-07 28.6 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 VBB32133.1 - 8.1e-13 48.0 1.3 2e-12 46.7 1.3 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 VBB32133.1 - 2.3e-12 45.8 1.6 4.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 VBB32133.1 - 1.3e-05 25.1 0.5 2.9e-05 23.9 0.5 1.7 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 VBB32133.1 - 0.0019 18.5 0.1 0.0033 17.7 0.1 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 VBB32133.1 - 0.0077 16.4 0.8 0.41 10.9 1.1 2.2 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_11 PF08976.11 VBB32133.1 - 0.011 16.6 0.1 0.013 16.3 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_9 PF14658.6 VBB32133.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 VBB32134.1 - 0.00038 20.9 0.2 0.00062 20.2 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB32134.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 VBB32135.1 - 6.1e-40 137.2 0.0 8.1e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32135.1 - 1e-10 41.4 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 VBB32136.1 - 8.9e-40 135.2 7.5 3.2e-17 62.9 0.1 5.2 4 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB32136.1 - 1.3e-34 118.1 12.1 9.5e-08 32.4 0.1 7.1 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB32136.1 - 1.3e-32 108.1 13.9 0.0014 18.9 0.0 9.4 8 1 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 VBB32136.1 - 1.2e-30 104.6 15.4 2e-05 24.8 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 VBB32136.1 - 7.1e-30 102.7 11.6 0.00013 22.2 0.0 7.8 5 2 3 8 8 8 7 Ankyrin repeats (many copies) SAD_SRA PF02182.17 VBB32136.1 - 0.15 11.7 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 SAD/SRA domain LIM PF00412.22 VBB32137.1 - 5.6e-14 52.1 4.9 7.1e-14 51.8 4.9 1.2 1 0 0 1 1 1 1 LIM domain zf-SNAP50_C PF12251.8 VBB32137.1 - 0.067 12.9 0.2 0.07 12.8 0.2 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-DNA_Pol PF08996.10 VBB32137.1 - 0.34 10.7 2.9 0.37 10.5 2.9 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger RRM_7 PF16367.5 VBB32138.1 - 7.5e-15 54.8 0.0 1.2e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif CEBP_ZZ PF16366.5 VBB32138.1 - 5.1e-14 52.2 3.0 1.1e-13 51.2 1.8 2.0 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 VBB32138.1 - 9.4e-07 28.6 0.0 0.00027 20.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C1_2 PF03107.16 VBB32138.1 - 7.3 7.0 8.7 0.93 9.9 3.2 2.1 2 0 0 2 2 2 0 C1 domain Guanylate_cyc PF00211.20 VBB32140.1 - 2.1e-21 76.4 0.0 1.1e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 VBB32140.1 - 0.12 12.9 0.2 0.4 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Chordopox_A13L PF05961.11 VBB32140.1 - 2.9 8.2 6.4 1 9.7 0.3 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF4191 PF13829.6 VBB32140.1 - 3.9 6.8 5.0 9 5.6 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) WW PF00397.26 VBB32141.1 - 4.6e-06 26.6 3.3 1e-05 25.5 3.3 1.6 1 0 0 1 1 1 1 WW domain CDC45 PF02724.14 VBB32141.1 - 9.4 4.4 8.0 15 3.7 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1c PF00749.21 VBB32142.1 - 4.8e-112 373.9 1.2 4.8e-112 373.9 1.2 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 VBB32142.1 - 1.1e-57 192.0 29.3 1.6e-17 63.4 0.4 4.8 4 0 0 4 4 4 4 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 VBB32142.1 - 5.9e-33 114.2 0.9 2.1e-32 112.4 0.9 2.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b PF00587.25 VBB32142.1 - 9.4e-18 64.8 0.0 3.9e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF5460 PF17544.2 VBB32142.1 - 3.3e-05 23.1 1.7 0.0078 15.3 0.1 3.5 2 1 2 4 4 4 2 Family of unknown function (DUF5460) tRNA-synt_1e PF01406.19 VBB32142.1 - 0.0002 20.8 0.1 0.00059 19.3 0.1 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C PF00043.25 VBB32142.1 - 0.025 14.8 0.1 0.46 10.7 0.0 2.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 VBB32142.1 - 0.04 14.1 0.1 0.48 10.7 0.1 3.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1993 PF09351.10 VBB32142.1 - 0.078 13.1 9.9 0.07 13.3 1.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1993) GST_C_2 PF13410.6 VBB32142.1 - 0.1 12.7 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain T2SSM PF04612.12 VBB32142.1 - 3.1 7.8 4.5 5.1 7.1 1.1 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Death PF00531.22 VBB32143.1 - 2.5e-11 43.6 1.5 6.5e-11 42.2 0.1 2.2 2 0 0 2 2 2 1 Death domain UPA_2 PF17809.1 VBB32143.1 - 0.012 15.4 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 UPA domain Metallophos PF00149.28 VBB32147.1 - 9.9e-09 36.0 0.0 1.4e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 7TM_GPCR_Srx PF10328.9 VBB32148.1 - 1.1e-11 44.9 4.3 1.3e-11 44.6 4.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 VBB32149.1 - 1.5e-35 122.8 15.4 2.1e-35 122.4 15.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 VBB32149.1 - 1.7e-05 24.3 4.6 1.7e-05 24.3 4.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 VBB32149.1 - 1.9e-05 24.5 6.0 1.9e-05 24.5 6.0 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Diphthamide_syn PF01866.17 VBB32150.1 - 1.1e-109 366.5 0.1 1.4e-109 366.2 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Histone PF00125.24 VBB32150.1 - 3e-15 56.7 0.0 6.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB32150.1 - 2.1e-06 27.9 0.0 6.4e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 VBB32150.1 - 4.9e-05 23.0 0.1 0.0001 22.0 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A PP2C PF00481.21 VBB32152.1 - 3.5e-37 128.4 0.0 5.4e-35 121.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Oxysterol_BP PF01237.18 VBB32153.1 - 6.2e-76 255.6 0.2 3.9e-74 249.7 0.1 2.6 2 1 0 2 2 2 1 Oxysterol-binding protein DUF1674 PF07896.12 VBB32153.1 - 4.6e-18 65.4 2.2 1.3e-17 64.0 2.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) PH PF00169.29 VBB32153.1 - 1.8e-13 50.9 0.0 4.7e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 VBB32153.1 - 2.4e-07 31.1 1.8 6.8e-06 26.5 1.8 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 VBB32153.1 - 2.7e-06 27.5 0.1 6.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 VBB32153.1 - 0.006 16.7 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Strumpellin PF10266.9 VBB32154.1 - 2e-36 125.2 2.8 2.3e-36 125.0 2.8 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin LBP_BPI_CETP PF01273.25 VBB32155.1 - 2.4e-22 79.3 0.0 5.2e-22 78.2 0.0 1.5 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Ribonuc_red_sm PF00268.21 VBB32155.1 - 0.1 12.0 0.2 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Ribonucleotide reductase, small chain KH_1 PF00013.29 VBB32156.1 - 1.6e-16 59.9 0.8 4.3e-14 52.1 0.6 3.2 3 0 0 3 3 3 1 KH domain SAM_1 PF00536.30 VBB32156.1 - 1.9e-14 53.8 0.1 4.6e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB32156.1 - 2.2e-09 37.3 0.1 6.3e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 VBB32156.1 - 1.2e-05 25.6 5.3 0.0091 16.4 0.0 4.7 4 1 1 5 5 5 1 GLD-3 KH domain 5 Nrf1_activ_bdg PF10492.9 VBB32156.1 - 0.066 13.9 0.4 0.3 11.8 0.4 2.1 1 0 0 1 1 1 0 Nrf1 activator activation site binding domain Col_cuticle_N PF01484.17 VBB32157.1 - 3e-18 65.6 0.6 4e-18 65.2 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB32158.1 - 1.1e-19 69.9 102.5 8.9e-08 31.8 36.7 4.1 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32158.1 - 2.1e-18 66.1 0.7 2.9e-18 65.6 0.7 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Arf PF00025.21 VBB32159.1 - 1.5e-40 138.5 0.2 4.1e-40 137.1 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 VBB32159.1 - 1.1e-07 31.4 0.1 1.1e-07 31.4 0.1 3.6 1 1 1 3 3 3 2 G-protein alpha subunit Roc PF08477.13 VBB32159.1 - 9.1e-06 25.9 0.0 4.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB32159.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 VBB32159.1 - 0.0071 16.4 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 VBB32159.1 - 0.058 13.9 3.0 0.13 12.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain Ribosomal_60s PF00428.19 VBB32160.1 - 4.6e-27 94.4 4.0 6.7e-27 93.9 4.0 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L27A PF00828.19 VBB32161.1 - 8.8e-26 91.1 0.0 1.2e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A EIF_2_alpha PF07541.12 VBB32162.1 - 1.3e-34 118.8 0.3 9.3e-34 116.0 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit Band_7 PF01145.25 VBB32162.1 - 3.4e-20 72.8 0.8 3.4e-20 72.8 0.8 2.2 1 1 1 2 2 2 1 SPFH domain / Band 7 family S1 PF00575.23 VBB32162.1 - 3.2e-13 49.8 0.6 6.3e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain ODAM PF15424.6 VBB32162.1 - 0.12 12.0 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Odontogenic ameloblast-associated family An_peroxidase PF03098.15 VBB32163.1 - 8.6e-67 225.9 0.0 1e-66 225.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Pre-PUA PF17832.1 VBB32164.1 - 0.068 13.9 0.5 0.19 12.4 0.5 1.8 1 0 0 1 1 1 0 Pre-PUA-like domain Ion_trans_2 PF07885.16 VBB32165.1 - 2.9e-20 72.0 21.3 4.5e-12 45.7 13.0 3.6 4 0 0 4 4 4 2 Ion channel fn3 PF00041.21 VBB32165.1 - 3.1e-18 65.9 0.3 8.1e-10 38.9 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB32165.1 - 0.0014 19.2 0.4 1.8 9.2 0.0 2.7 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 VBB32165.1 - 0.0066 16.7 0.1 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III DUF4401 PF14351.6 VBB32166.1 - 0.038 13.3 0.1 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) tRNA-synt_1c_C PF03950.18 VBB32166.1 - 0.41 10.5 7.1 0.85 9.5 0.5 3.3 3 1 0 3 3 3 0 tRNA synthetases class I (E and Q), anti-codon binding domain FUSC_2 PF13515.6 VBB32166.1 - 3.9 7.6 6.0 4.4 7.4 1.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Cys_knot PF00007.22 VBB32167.1 - 4e-06 27.1 2.6 4.2e-06 27.0 2.6 1.0 1 0 0 1 1 1 1 Cystine-knot domain 7tm_1 PF00001.21 VBB32168.1 - 8.9e-49 166.2 2.7 1.1e-48 165.9 2.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB32168.1 - 2.8e-06 26.9 5.9 4.5e-06 26.2 5.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 VBB32168.1 - 1.3e-05 25.1 3.8 1.9e-05 24.5 3.8 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 VBB32168.1 - 3.5e-05 23.5 8.7 3.5e-05 23.5 8.7 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.9 VBB32168.1 - 1 8.9 18.6 0.11 12.1 14.1 1.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx NHL PF01436.21 VBB32169.1 - 6.7e-31 104.8 18.5 9.2e-11 41.2 0.2 6.0 6 0 0 6 6 6 5 NHL repeat zf-B_box PF00643.24 VBB32169.1 - 1.2e-08 35.0 27.4 2.8e-06 27.4 8.8 5.1 5 1 0 5 5 5 2 B-box zinc finger DUF5128 PF17170.4 VBB32169.1 - 6.5e-08 32.1 3.9 0.00017 20.9 0.1 2.9 2 1 0 2 2 2 2 6-bladed beta-propeller zf-RING_UBOX PF13445.6 VBB32169.1 - 5.6e-07 29.5 9.4 5.6e-07 29.5 9.4 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 VBB32169.1 - 9.6e-07 28.7 11.2 9.6e-07 28.7 11.2 3.9 3 1 0 3 3 3 1 zinc-RING finger domain SGL PF08450.12 VBB32169.1 - 4.8e-06 26.3 0.2 0.059 12.9 0.0 3.4 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4 PF00097.25 VBB32169.1 - 2.4e-05 24.1 12.6 2.4e-05 24.1 12.6 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB32169.1 - 4.2e-05 23.6 13.6 4.2e-05 23.6 13.6 4.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 VBB32169.1 - 7.3e-05 23.0 11.9 7.3e-05 23.0 11.9 3.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB32169.1 - 0.0001 22.1 13.1 0.0001 22.1 13.1 3.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) DUF4934 PF16288.5 VBB32169.1 - 0.0064 16.4 0.5 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4934) TPR_19 PF14559.6 VBB32171.1 - 0.013 16.0 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat GST_N_3 PF13417.6 VBB32171.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF749 PF05370.11 VBB32172.1 - 0.14 12.3 1.6 0.45 10.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF749) Ribosomal_L50 PF10501.9 VBB32173.1 - 1.3e-09 38.2 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S zf-HC5HC2H_2 PF13832.6 VBB32174.1 - 1.8e-28 98.9 10.2 1.8e-28 98.9 10.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 VBB32174.1 - 7.2e-21 74.2 6.3 7.2e-21 74.2 6.3 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 VBB32174.1 - 3.6e-12 45.6 3.5 3.6e-12 45.6 3.5 3.3 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 VBB32174.1 - 2.3e-09 37.0 11.1 2.3e-09 37.0 11.1 3.3 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 VBB32174.1 - 0.00077 19.9 0.0 0.0017 18.7 0.0 1.6 1 1 0 1 1 1 1 Enhancer of polycomb-like Prok-RING_1 PF14446.6 VBB32174.1 - 6.4 6.8 22.7 0.14 12.1 7.7 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 VBB32174.1 - 7.4 6.2 19.3 0.021 14.5 4.1 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain LRR_4 PF12799.7 VBB32175.1 - 7.6e-09 35.7 10.3 0.00014 22.2 1.4 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB32175.1 - 8.7e-09 35.1 5.4 3.1e-08 33.3 4.8 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 VBB32175.1 - 0.00079 19.1 8.1 0.11 12.3 7.0 2.8 1 1 1 2 2 2 2 Leucine rich repeat Cas_Csn2 PF09711.10 VBB32175.1 - 0.051 13.2 2.5 9.2 5.9 1.6 2.6 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) Serpin PF00079.20 VBB32176.1 - 8.9e-10 38.4 2.0 9.2e-06 25.2 0.0 2.7 2 1 1 3 3 3 2 Serpin (serine protease inhibitor) CPG4 PF15481.6 VBB32177.1 - 3.9e-13 49.8 4.2 3.9e-13 49.8 4.2 2.1 2 0 0 2 2 2 1 Chondroitin proteoglycan 4 CDC24_OB3 PF17244.2 VBB32178.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 TFIIB PF00382.19 VBB32179.1 - 6.9e-31 106.1 0.8 2.8e-14 52.9 0.1 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 VBB32179.1 - 5.4e-24 84.5 12.4 5.4e-24 84.5 12.4 3.4 4 1 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 VBB32179.1 - 2.4e-11 42.9 2.2 7.1e-11 41.4 2.2 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 VBB32179.1 - 2.2e-06 27.5 0.5 0.00054 19.7 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain Ribosomal_S27e PF01667.17 VBB32179.1 - 0.05 13.3 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 2Fe-2S_thioredx PF01257.19 VBB32179.1 - 0.1 12.5 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin zf-ribbon_3 PF13248.6 VBB32179.1 - 0.53 9.8 5.6 3.1 7.3 5.6 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Cation_ATPase_C PF00689.21 VBB32180.1 - 0.2 11.4 2.7 1.1 8.9 0.9 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus WAP PF00095.21 VBB32181.1 - 3.1e-09 37.1 15.6 3.1e-09 37.1 15.6 1.7 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' fn3 PF00041.21 VBB32181.1 - 2.6e-06 27.7 1.4 1.1e-05 25.7 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III domain CRAM_rpt PF07016.11 VBB32181.1 - 0.95 9.3 6.1 1.9 8.4 6.1 1.5 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor Conotoxin_I2 PF17557.2 VBB32181.1 - 5.2 7.3 15.4 0.64 10.2 10.4 2.0 2 0 0 2 2 2 0 I2-superfamily conotoxins Adaptin_binding PF10199.9 VBB32182.1 - 0.0002 21.9 1.4 0.00047 20.8 1.4 1.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 CAS_C PF12026.8 VBB32183.1 - 4.8e-35 121.6 0.5 1.3e-34 120.1 0.5 1.8 1 0 0 1 1 1 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 VBB32183.1 - 2.8e-18 66.4 1.7 7.6e-18 65.0 0.1 2.4 3 0 0 3 3 3 1 Serine rich protein interaction domain Osmo_CC PF08946.10 VBB32183.1 - 0.063 13.5 0.9 0.18 12.1 0.4 2.1 1 1 1 2 2 2 0 Osmosensory transporter coiled coil MFS_1 PF07690.16 VBB32184.1 - 1.6e-10 40.4 10.0 2.2e-10 40.0 10.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3561 PF12084.8 VBB32184.1 - 0.0045 17.0 1.4 0.0081 16.2 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3561) Rhomboid PF01694.22 VBB32185.1 - 4.7e-25 88.4 8.5 4.7e-25 88.4 8.5 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 VBB32185.1 - 0.18 12.4 1.6 0.21 12.2 0.3 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Astacin PF01400.24 VBB32186.1 - 6.3e-54 182.5 0.0 9.4e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DCX PF03607.17 VBB32187.1 - 7.8e-11 41.9 0.0 2.7e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Doublecortin YjcZ PF13990.6 VBB32187.1 - 0.04 13.3 1.7 0.073 12.4 1.7 1.3 1 0 0 1 1 1 0 YjcZ-like protein GIDA PF01134.22 VBB32188.1 - 6.4e-139 463.4 0.0 8.3e-139 463.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 VBB32188.1 - 7.2e-64 215.8 0.1 1e-63 215.3 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 VBB32188.1 - 5.1e-06 25.9 0.8 3.1e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 VBB32188.1 - 2.6e-05 23.7 0.1 3.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 VBB32188.1 - 0.00025 20.3 0.7 0.00025 20.3 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 VBB32188.1 - 0.00061 18.6 1.4 0.037 12.7 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 VBB32188.1 - 0.003 16.9 0.1 0.0062 15.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 VBB32188.1 - 0.011 16.3 0.1 0.033 14.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 VBB32188.1 - 0.14 12.4 0.8 0.33 11.2 0.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 VBB32188.1 - 0.14 11.1 0.4 0.38 9.7 0.4 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 VBB32188.1 - 0.31 10.6 4.6 2.5 7.6 1.9 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase 2OG-FeII_Oxy_3 PF13640.6 VBB32189.1 - 7.8e-05 23.5 0.0 9.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hint PF01079.20 VBB32190.1 - 4.9e-39 134.0 0.0 8.8e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Hint module Collagen PF01391.18 VBB32190.1 - 7.1e-24 83.3 84.0 2.9e-09 36.6 28.8 3.7 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Imm10 PF15588.6 VBB32190.1 - 0.032 14.4 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 10 Hint_2 PF13403.6 VBB32190.1 - 0.068 13.5 0.0 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 Hint domain DUF1713 PF08213.11 VBB32191.1 - 1.5 8.8 22.5 5.1 7.1 22.2 2.1 1 1 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) fn3 PF00041.21 VBB32192.1 - 3.3e-49 165.2 10.9 2.1e-10 40.8 0.3 10.0 9 1 0 9 9 9 8 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB32192.1 - 2.7e-14 53.5 1.5 0.00012 22.6 0.0 5.7 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 VBB32192.1 - 0.01 16.2 0.0 5.4 7.5 0.0 4.3 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 VBB32192.1 - 0.14 12.3 0.0 8.8 6.6 0.0 3.7 4 0 0 4 4 4 0 Fibronectin type III domain zf-HC5HC2H PF13771.6 VBB32193.1 - 0.00032 20.9 3.2 0.0023 18.1 0.2 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain Mpp10 PF04006.12 VBB32193.1 - 1.2 7.5 10.1 1.5 7.2 10.1 1.0 1 0 0 1 1 1 0 Mpp10 protein Eapp_C PF10238.9 VBB32193.1 - 9.1 6.3 8.6 1e+02 2.9 8.6 2.2 1 1 0 1 1 1 0 E2F-associated phosphoprotein DUF2153 PF09921.9 VBB32194.1 - 0.0012 18.7 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2153) F-box PF00646.33 VBB32194.1 - 0.031 14.2 0.8 0.079 12.9 0.2 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 VBB32194.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 F-box-like zf-H2C2_5 PF13909.6 VBB32195.1 - 5e-11 42.1 3.4 9.3e-07 28.5 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 VBB32195.1 - 0.00042 20.9 12.9 0.31 12.0 1.7 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB32195.1 - 0.0031 17.9 11.9 0.046 14.2 2.5 4.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.7 VBB32195.1 - 0.033 14.6 2.3 8.6 6.9 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB32195.1 - 0.11 12.9 2.1 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 VBB32195.1 - 0.24 11.7 7.4 2.6 8.4 0.3 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.12 VBB32195.1 - 0.42 10.8 3.4 0.9 9.8 0.1 2.8 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) GAGA PF09237.11 VBB32195.1 - 2.1 8.2 9.6 2 8.3 0.0 3.8 4 0 0 4 4 4 0 GAGA factor zf-C2H2_4 PF13894.6 VBB32196.1 - 3.9e-10 39.7 1.3 0.00039 21.0 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB32196.1 - 4.8e-10 39.3 1.1 0.00069 19.9 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 VBB32196.1 - 2.2e-07 30.7 1.3 2e-05 24.4 0.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB32196.1 - 0.00029 21.0 0.0 0.06 13.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB32196.1 - 0.0041 17.5 0.7 2 8.9 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 VBB32196.1 - 0.0094 15.5 0.2 0.87 9.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 VBB32196.1 - 0.013 15.2 0.1 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type XPA_N PF01286.18 VBB32196.1 - 0.04 14.0 0.9 0.65 10.1 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal PRR18 PF15671.5 VBB32196.1 - 0.05 13.5 4.2 0.079 12.8 4.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 Acyltransf_C PF16076.5 VBB32197.1 - 1.3e-10 41.3 0.3 2.7e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 VBB32197.1 - 1.5e-06 27.9 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Corona_RPol_N PF06478.13 VBB32197.1 - 0.09 11.8 0.1 0.09 11.8 0.1 1.8 2 0 0 2 2 2 0 Coronavirus RPol N-terminus Y_phosphatase PF00102.27 VBB32199.1 - 1.5e-42 145.8 0.3 2.4e-42 145.1 0.2 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DUF4048 PF13257.6 VBB32199.1 - 0.0058 16.5 6.3 0.0074 16.2 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4048) DSPc PF00782.20 VBB32199.1 - 0.0066 16.3 1.3 0.0066 16.3 1.3 1.9 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB32199.1 - 0.018 15.0 1.9 0.032 14.2 1.9 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Sec62 PF03839.16 VBB32199.1 - 0.28 10.6 3.2 0.49 9.9 3.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIIAH PF12685.7 VBB32199.1 - 3.2 7.5 8.1 4.6 7.0 8.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein YebO PF13974.6 VBB32200.1 - 0.0027 17.8 0.7 0.0027 17.8 0.7 1.6 2 0 0 2 2 2 1 YebO-like protein Cwf_Cwc_15 PF04889.12 VBB32200.1 - 0.022 14.5 7.3 0.031 14.0 7.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ATP-grasp_2 PF08442.10 VBB32201.1 - 1.1e-70 237.3 0.7 2.2e-70 236.4 0.0 1.8 2 1 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 VBB32201.1 - 5.7e-25 87.9 2.9 1.1e-24 87.0 2.9 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 VBB32201.1 - 4.6e-07 29.5 1.2 7.7e-06 25.5 0.1 3.0 2 1 0 2 2 2 1 ATP-grasp domain PAP2_C PF14360.6 VBB32202.1 - 2.6e-21 75.9 7.9 2.6e-21 75.9 7.9 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 VBB32202.1 - 1e-05 25.3 2.7 1e-05 25.3 2.7 2.6 3 1 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 VBB32202.1 - 0.0005 19.8 8.0 0.00092 18.9 8.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily Jagunal PF07086.12 VBB32204.1 - 4.1e-56 190.0 0.1 4.7e-56 189.8 0.1 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis MutL_C PF08676.11 VBB32205.1 - 1.7e-27 96.0 0.0 3.6e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain XPA_C PF05181.12 VBB32205.1 - 7.8e-24 83.4 1.0 1.6e-23 82.4 1.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus DNA_mis_repair PF01119.19 VBB32205.1 - 1.3e-16 60.3 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain XPA_N PF01286.18 VBB32205.1 - 1.7e-10 40.8 6.5 6.4e-10 38.9 6.5 2.1 1 0 0 1 1 1 1 XPA protein N-terminal HATPase_c_3 PF13589.6 VBB32205.1 - 2.4e-10 40.4 0.0 6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 VBB32205.1 - 0.00047 20.7 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3179 PF11376.8 VBB32205.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) Ion_trans_2 PF07885.16 VBB32206.1 - 1.8e-28 98.3 20.4 4.2e-17 61.9 6.3 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 VBB32206.1 - 9.2e-05 21.8 13.8 0.0067 15.7 6.2 2.3 2 0 0 2 2 2 2 Ion transport protein UPF0640 PF15114.6 VBB32206.1 - 0.0042 16.8 3.6 0.022 14.6 0.4 2.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0640 IRK PF01007.20 VBB32206.1 - 0.039 13.8 1.8 4.1 7.2 0.2 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain RAMP4 PF06624.12 VBB32206.1 - 0.083 13.0 0.0 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 SMG1 PF15785.5 VBB32206.1 - 0.21 9.9 0.7 0.29 9.5 0.7 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 N6-adenineMlase PF10237.9 VBB32208.1 - 1.1e-20 74.1 0.3 1.8e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase V-ATPase_H_C PF11698.8 VBB32208.1 - 0.082 13.0 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 V-ATPase subunit H Sec6 PF06046.13 VBB32209.1 - 8.2e-95 318.3 7.1 8e-94 315.1 3.3 2.5 2 1 0 2 2 2 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.14 VBB32209.1 - 1.5 8.7 5.7 0.77 9.6 0.6 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain S4 PF01479.25 VBB32210.1 - 1.5e-11 43.9 0.1 2.8e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 VBB32210.1 - 1.9e-07 31.9 0.4 4.1e-07 30.8 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Exog_C PF18026.1 VBB32210.1 - 0.13 12.3 1.6 15 5.7 0.1 3.3 3 1 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain PHTB1_C PF14728.6 VBB32211.1 - 2.6e-43 148.5 5.4 4.4e-43 147.8 5.4 1.3 1 0 0 1 1 1 1 PTHB1 C-terminus VWD PF00094.25 VBB32211.1 - 1.2e-24 87.4 0.1 2.8e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 VBB32211.1 - 1.8e-17 63.4 91.6 3.5e-07 30.4 10.2 5.6 5 0 0 5 5 5 5 von Willebrand factor type C domain PHTB1_N PF14727.6 VBB32211.1 - 8.9e-16 58.3 0.0 1.4e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus TILa PF12714.7 VBB32211.1 - 0.01 15.8 10.3 0.01 15.8 10.3 5.6 5 1 0 5 5 5 3 TILa domain RNA_pol_Rpb4 PF03874.16 VBB32211.1 - 0.19 12.0 2.2 0.47 10.8 2.2 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb4 HLH PF00010.26 VBB32212.1 - 3.8e-12 46.0 0.9 8.7e-12 44.8 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 VBB32212.1 - 0.00076 19.2 2.9 0.00076 19.2 2.9 1.6 2 0 0 2 2 2 1 Septum formation initiator ZapB PF06005.12 VBB32212.1 - 0.0096 16.4 1.6 0.0096 16.4 1.6 1.9 2 1 0 2 2 2 1 Cell division protein ZapB HALZ PF02183.18 VBB32212.1 - 0.045 14.0 1.2 0.045 14.0 1.2 2.1 2 2 1 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 VBB32212.1 - 0.81 10.4 5.3 0.78 10.4 3.6 1.8 1 1 0 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 VBB32212.1 - 1.9 8.6 6.6 2.9 8.0 6.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PLDc_2 PF13091.6 VBB32213.1 - 7.2e-15 55.0 0.0 2.5e-06 27.4 0.0 2.6 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 VBB32213.1 - 1.5e-07 31.3 1.7 0.00071 19.7 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PAX PF00292.18 VBB32215.1 - 7.5e-54 181.0 0.2 1.1e-53 180.5 0.2 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 VBB32215.1 - 5.9e-07 29.1 0.2 1.2e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 VBB32215.1 - 4.5e-05 24.0 0.1 0.0026 18.3 0.0 2.2 1 1 1 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 VBB32215.1 - 0.00053 20.0 0.1 0.005 16.9 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 VBB32215.1 - 0.035 13.9 0.3 0.035 13.9 0.3 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_ABP1_N PF18107.1 VBB32215.1 - 0.8 9.5 2.7 39 4.1 0.1 3.1 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain Pro_isomerase PF00160.21 VBB32216.1 - 7.7e-49 166.0 0.2 8.9e-49 165.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 VBB32217.1 - 3.5e-46 156.8 0.1 5.6e-45 152.8 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB32217.1 - 6.1e-29 100.7 0.1 2.9e-28 98.5 0.1 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB32217.1 - 8.9e-09 35.0 0.1 1.1e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB32217.1 - 5.1e-06 26.0 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 VBB32217.1 - 0.0014 18.1 0.0 0.034 13.6 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 VBB32217.1 - 0.002 18.0 0.3 0.66 9.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 VBB32217.1 - 0.0021 17.8 0.1 0.78 9.5 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 VBB32217.1 - 0.0025 17.9 0.0 0.0055 16.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB32217.1 - 0.022 14.3 0.1 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 VBB32217.1 - 0.13 11.8 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PcrB PF01884.17 VBB32218.1 - 0.096 12.1 0.1 14 5.1 0.0 2.1 2 0 0 2 2 2 0 PcrB family TMEM151 PF14857.6 VBB32219.1 - 3.1e-98 329.5 2.3 3.9e-98 329.2 2.3 1.1 1 0 0 1 1 1 1 TMEM151 family DUF2802 PF10975.8 VBB32219.1 - 0.053 13.6 0.4 0.65 10.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DNA_processg_A PF02481.15 VBB32219.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A RhoGAP PF00620.27 VBB32220.1 - 4.8e-29 101.1 0.0 1.1e-28 99.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF3326 PF11805.8 VBB32220.1 - 0.17 10.7 0.1 0.33 9.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) TMEM189_B_dmain PF10520.9 VBB32221.1 - 6.2e-07 29.7 0.2 9.6e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain fn3 PF00041.21 VBB32222.1 - 1.9e-144 470.4 72.2 3.7e-15 56.0 0.1 21.6 20 2 0 20 20 20 18 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB32222.1 - 2.5e-28 98.5 43.5 0.00015 22.2 0.0 17.6 19 0 0 19 19 19 8 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 VBB32222.1 - 6.3e-07 29.3 2.8 15 5.6 0.0 9.2 9 0 0 9 9 9 1 Fibronectin-III type domain DUF2369 PF10179.9 VBB32222.1 - 4.5e-06 27.0 1.5 2.7 8.4 0.1 7.3 7 0 0 7 7 7 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 VBB32222.1 - 0.00031 20.8 0.0 5 7.3 0.0 5.7 5 0 0 5 5 5 1 Fibronectin type III domain F5_F8_type_C PF00754.25 VBB32222.1 - 0.0007 19.7 20.5 0.81 9.8 0.1 7.1 9 0 0 9 9 9 3 F5/8 type C domain SusE PF14292.6 VBB32222.1 - 0.02 15.1 0.1 25 5.1 0.0 4.3 3 0 0 3 3 3 0 SusE outer membrane protein Glyco_hydro_66 PF13199.6 VBB32222.1 - 0.048 12.3 0.0 2.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 66 Big_5 PF13205.6 VBB32222.1 - 0.1 13.3 5.6 5.5 7.7 0.1 5.3 5 0 0 5 5 5 0 Bacterial Ig-like domain Asp-B-Hydro_N PF05279.11 VBB32222.1 - 0.85 9.6 20.7 1.4 8.9 20.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DHHC PF01529.20 VBB32223.1 - 6.8e-35 120.1 9.5 6.8e-35 120.1 9.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 VBB32223.1 - 0.045 13.6 0.5 0.08 12.9 0.5 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2418 PF10332.9 VBB32223.1 - 1.6 9.3 4.5 25 5.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DZR PF12773.7 VBB32223.1 - 5.8 7.0 11.5 5.7 7.1 9.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon zf-UBR PF02207.20 VBB32224.1 - 2.4e-13 50.1 12.4 2.4e-13 50.1 12.4 3.2 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) LEH PF07858.12 VBB32224.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain PIG-U PF06728.13 VBB32225.1 - 1.4e-76 258.1 35.8 1.7e-67 228.2 36.7 2.1 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 VBB32225.1 - 1.4 8.7 31.5 2.6 7.8 29.4 2.3 2 1 0 2 2 2 0 Mannosyltransferase (PIG-M) E3_UFM1_ligase PF09743.9 VBB32226.1 - 9.6e-30 104.1 0.3 3.4e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 DUF3788 PF12663.7 VBB32226.1 - 0.044 13.7 0.2 0.15 12.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) AA_kinase PF00696.28 VBB32226.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family TraB PF01963.17 VBB32227.1 - 1.6e-45 156.1 0.0 1.9e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 TraB family CoA_binding PF02629.19 VBB32228.1 - 1.7e-28 99.1 0.8 1.7e-28 99.1 0.8 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 VBB32228.1 - 2.9e-23 82.4 1.1 4.9e-23 81.6 0.2 1.8 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 VBB32228.1 - 1.9e-08 34.2 0.0 3.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 VBB32228.1 - 0.0018 18.7 0.1 0.0044 17.5 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain G-alpha PF00503.20 VBB32229.1 - 3.1e-80 270.0 9.4 3.4e-80 269.9 9.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB32229.1 - 9.7e-13 47.9 0.3 2.3e-12 46.7 0.3 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Latarcin PF10279.9 VBB32229.1 - 0.48 10.9 3.4 0.61 10.5 0.1 2.7 3 1 0 3 3 3 0 Latarcin precursor Cation_ATPase_C PF00689.21 VBB32230.1 - 1.8e-41 141.9 5.9 3.3e-41 141.0 5.9 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.8 VBB32230.1 - 2.1e-10 40.9 0.2 6e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 VBB32230.1 - 0.00014 21.7 1.3 0.00014 21.7 1.3 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB32230.1 - 0.087 13.1 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF745 PF05335.13 VBB32232.1 - 0.019 14.7 0.2 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SprT-like PF10263.9 VBB32233.1 - 6.1e-29 100.2 0.0 1.2e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 VBB32233.1 - 0.013 15.8 0.0 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Effector protein zf_UBZ PF18439.1 VBB32233.1 - 0.079 12.6 0.4 0.16 11.6 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 VBB32233.1 - 0.12 13.1 4.3 0.32 11.7 4.3 1.7 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain PRP21_like_P PF12230.8 VBB32233.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein WLM PF08325.10 VBB32233.1 - 0.34 10.9 1.2 0.67 10.0 0.1 1.9 2 0 0 2 2 2 0 WLM domain CRM1_C PF08767.11 VBB32234.1 - 9.5e-106 353.6 9.4 9.5e-106 353.6 9.4 2.7 3 0 0 3 3 3 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 VBB32234.1 - 2.7e-34 116.6 3.3 2.7e-34 116.6 3.3 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 VBB32234.1 - 1.9e-30 104.7 1.4 3e-29 100.9 0.9 3.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 Xpo1 PF08389.12 VBB32234.1 - 2.6e-21 76.3 0.2 2.6e-21 76.3 0.2 5.1 4 1 1 5 5 5 1 Exportin 1-like protein CRM1_repeat PF18777.1 VBB32234.1 - 2.3e-19 68.6 1.9 5.6e-19 67.4 1.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat MOZART2 PF12926.7 VBB32234.1 - 0.14 11.8 3.1 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated zf-UBP PF02148.19 VBB32236.1 - 5.8e-18 65.0 12.6 8.2e-18 64.5 12.6 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 VBB32236.1 - 0.0059 16.3 2.2 0.011 15.5 2.2 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger UBA PF00627.31 VBB32237.1 - 2.2e-06 27.4 2.5 4e-06 26.6 0.8 2.2 2 0 0 2 2 2 1 UBA/TS-N domain DUF1751 PF08551.10 VBB32237.1 - 0.0052 17.3 0.6 0.0052 17.3 0.6 2.2 2 1 1 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF1296 PF06972.11 VBB32237.1 - 0.034 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) HOIP-UBA PF16678.5 VBB32237.1 - 0.082 12.9 0.3 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair TFIIF_beta PF02270.15 VBB32238.1 - 6.4e-24 83.9 0.1 1.5e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 VBB32238.1 - 1.1e-20 74.7 0.0 2.7e-19 70.2 0.0 2.4 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Stealth_CR4 PF17103.5 VBB32238.1 - 0.046 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 HOOK PF05622.12 VBB32239.1 - 3.5e-13 48.6 27.3 5.1e-13 48.1 27.3 1.2 1 0 0 1 1 1 1 HOOK protein ATP-synt_B PF00430.18 VBB32239.1 - 0.0027 17.8 3.9 0.0027 17.8 3.9 2.4 3 0 0 3 3 2 1 ATP synthase B/B' CF(0) ATG16 PF08614.11 VBB32239.1 - 0.013 15.7 12.8 0.013 15.7 12.8 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 VBB32239.1 - 0.07 13.5 9.6 0.1 12.9 1.7 3.5 1 1 2 3 3 3 0 TSC-22/dip/bun family POTRA PF07244.15 VBB32239.1 - 0.11 13.1 0.1 0.35 11.5 0.1 2.0 1 0 0 1 1 1 0 Surface antigen variable number repeat MPS2 PF17060.5 VBB32239.1 - 0.18 11.0 13.9 0.75 9.0 13.8 1.9 1 1 0 1 1 1 0 Monopolar spindle protein 2 NitrOD1 PF18549.1 VBB32239.1 - 0.2 11.7 1.7 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 Nitrosopumilus output domain 1 DUF1707 PF08044.11 VBB32239.1 - 0.31 11.1 3.7 1.3 9.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) Fez1 PF06818.15 VBB32239.1 - 0.77 10.2 25.2 0.11 13.0 8.0 2.9 2 1 1 3 3 3 0 Fez1 GAS PF13851.6 VBB32239.1 - 0.78 9.1 27.6 0.45 9.8 11.7 3.0 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 VBB32239.1 - 1 9.1 22.2 0.5 10.2 4.9 3.5 2 2 2 4 4 4 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 VBB32239.1 - 1.8 8.7 15.1 3 8.0 1.0 4.1 2 1 1 3 3 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 VBB32239.1 - 3 7.9 31.0 0.14 12.2 5.1 3.6 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 VBB32239.1 - 5 5.9 29.4 0.18 10.7 8.6 2.9 1 1 1 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 VBB32239.1 - 5.2 7.4 22.7 1.7 9.0 5.4 3.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 VBB32239.1 - 6.5 7.3 16.3 0.25 11.9 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 HSP20 PF00011.21 VBB32240.1 - 7.1e-21 74.3 0.3 9.1e-21 73.9 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB32240.1 - 0.00052 19.5 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ground-like PF04155.18 VBB32242.1 - 4.7e-22 78.4 1.5 1.2e-21 77.2 1.5 1.7 1 0 0 1 1 1 1 Ground-like domain Collagen PF01391.18 VBB32243.1 - 7.9e-24 83.2 80.3 3.2e-10 39.6 29.9 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32243.1 - 5.9e-17 61.5 1.1 8.7e-17 60.9 1.1 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Collagen PF01391.18 VBB32244.1 - 1.2e-22 79.4 83.1 9e-09 35.0 27.5 3.9 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32244.1 - 1e-16 60.7 0.2 1.4e-16 60.2 0.2 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DUF531 PF04407.12 VBB32244.1 - 0.00024 21.3 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF531) MDD_C PF18376.1 VBB32245.1 - 4.2e-22 78.8 0.0 5.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain MDD_C PF18376.1 VBB32246.1 - 4.7e-29 101.5 0.2 6.8e-29 100.9 0.2 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 VBB32246.1 - 3.8e-05 23.8 0.7 8.8e-05 22.7 0.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain NYD-SP12_N PF15015.6 VBB32246.1 - 0.068 11.5 0.0 0.097 11.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DnaJ PF00226.31 VBB32247.1 - 3.9e-17 62.1 2.2 3.9e-17 62.1 2.2 2.0 2 0 0 2 2 2 1 DnaJ domain DUF3783 PF12646.7 VBB32247.1 - 0.082 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Abhydrolase_1 PF00561.20 VBB32249.1 - 1.5e-07 31.3 0.2 3.6e-07 30.1 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB32249.1 - 8.7e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 VBB32249.1 - 0.046 13.8 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 VBB32249.1 - 0.05 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 VBB32249.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 VBB32249.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Palm_thioest PF02089.15 VBB32249.1 - 0.086 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2974 PF11187.8 VBB32249.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Trans_coact PF16805.5 VBB32249.1 - 0.19 11.8 0.0 0.74 10.0 0.0 1.9 2 0 0 2 2 2 0 Phage late-transcription coactivator DM13 PF10517.9 VBB32251.1 - 0.00037 21.0 0.0 0.0016 19.0 0.0 1.8 1 1 1 2 2 2 1 Electron transfer DM13 Histone PF00125.24 VBB32252.1 - 3.6e-18 66.2 0.0 5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 VBB32252.1 - 2.5e-12 46.3 0.0 4.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 VBB32252.1 - 0.0024 18.1 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tubulin PF00091.25 VBB32253.1 - 3.6e-69 232.9 0.0 4.9e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB32253.1 - 1.3e-47 161.1 0.0 2.3e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 VBB32253.1 - 0.00025 20.8 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain PX PF00787.24 VBB32254.1 - 5.3e-10 39.3 0.1 8.6e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 PX domain Helicase_C_4 PF13871.6 VBB32254.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Complex1_49kDa PF00346.19 VBB32255.1 - 6.4e-119 396.0 0.0 8.3e-119 395.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 VBB32255.1 - 1.3e-05 24.3 0.0 2.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Nickel-dependent hydrogenase FANCI_S3 PF14677.6 VBB32256.1 - 0.0097 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 FANCI solenoid 3 cNMP_binding PF00027.29 VBB32257.1 - 3.9e-29 100.6 0.1 2.3e-11 43.6 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 VBB32257.1 - 1.7e-21 77.4 0.1 4.3e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Transglut_core PF01841.19 VBB32258.1 - 1.3e-10 41.7 0.1 2.9e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily EB PF01683.18 VBB32259.1 - 1.3e-06 28.6 0.3 1.3e-06 28.6 0.3 3.1 1 1 1 2 2 2 1 EB module Collagen PF01391.18 VBB32260.1 - 1.7e-25 88.5 118.3 1.2e-09 37.8 46.5 4.1 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32260.1 - 1.1e-20 73.4 0.3 1.3e-20 73.1 0.3 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain MBOAT PF03062.19 VBB32261.1 - 1.2e-15 57.7 4.6 1.9e-15 57.1 4.6 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family COesterase PF00135.28 VBB32262.1 - 9.5e-122 407.5 0.0 1.2e-121 407.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB32262.1 - 2.4e-05 24.3 0.0 9.5e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ldl_recept_a PF00057.18 VBB32264.1 - 3.1e-11 43.3 4.7 5.6e-11 42.5 4.7 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Laminin_EGF PF00053.24 VBB32265.1 - 2.6 8.3 24.3 1.8 8.7 7.4 2.5 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 VBB32265.1 - 5.6 7.4 22.1 0.56 10.6 2.0 3.8 3 1 1 4 4 4 0 EGF-like domain Peptidase_C2 PF00648.21 VBB32266.1 - 5.4e-128 426.2 0.4 1.1e-127 425.2 0.0 1.6 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 VBB32266.1 - 1.7e-40 138.5 0.0 3.1e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Ank_2 PF12796.7 VBB32268.1 - 8.9e-38 128.8 2.6 1e-11 45.2 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB32268.1 - 1.3e-28 99.0 9.0 3e-11 43.6 0.1 6.6 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 VBB32268.1 - 2.6e-27 94.0 7.7 5.3e-08 33.0 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 VBB32268.1 - 3.9e-25 85.2 5.4 7.3e-06 26.0 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 VBB32268.1 - 8.1e-21 73.8 11.4 0.00022 21.5 0.1 7.4 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ion_trans PF00520.31 VBB32268.1 - 1.4e-05 24.5 15.8 1.4e-05 24.5 15.8 2.1 2 0 0 2 2 2 1 Ion transport protein VWA_3_C PF18571.1 VBB32268.1 - 0.19 11.6 0.1 0.65 9.9 0.1 2.0 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain DUF3169 PF11368.8 VBB32269.1 - 0.012 15.1 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Adeno_E3_CR2 PF02439.15 VBB32269.1 - 0.058 13.2 3.0 3.4 7.5 0.2 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 7tm_1 PF00001.21 VBB32269.1 - 1.1 8.5 6.6 0.55 9.5 2.8 2.3 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4834 PF16118.5 VBB32269.1 - 3.3 8.7 6.3 64 4.6 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Glyco_transf_92 PF01697.27 VBB32270.1 - 5.4e-36 124.6 0.0 1.1e-35 123.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 VBB32270.1 - 0.0029 18.1 0.0 0.0078 16.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3295 PF11702.8 VBB32270.1 - 0.057 12.8 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) UCH PF00443.29 VBB32272.1 - 2.3e-45 155.1 0.1 3.4e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB32272.1 - 4.1e-09 36.5 3.8 4.6e-08 33.0 0.1 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 VBB32272.1 - 2.4e-08 34.2 1.1 8.5e-08 32.4 1.1 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TPR_1 PF00515.28 VBB32273.1 - 5.7e-10 38.6 3.2 0.00032 20.4 0.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB32273.1 - 7.9e-07 29.3 2.8 7.9e-07 29.3 2.8 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB32273.1 - 2.1e-06 27.3 3.1 0.021 14.8 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB32273.1 - 1.9e-05 24.4 5.9 0.071 13.3 0.2 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB32273.1 - 0.0011 19.0 3.7 0.033 14.4 0.1 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 VBB32273.1 - 0.0015 18.3 0.5 1.3 9.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1110 PF06533.12 VBB32273.1 - 0.031 14.2 0.3 0.084 12.8 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) TPR_17 PF13431.6 VBB32273.1 - 0.14 12.6 1.0 2.2 8.8 1.0 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 VBB32274.1 - 3e-59 196.8 0.3 1.3e-18 66.6 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB32274.1 - 8.9e-08 31.8 0.0 0.014 15.0 0.0 3.2 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB32274.1 - 0.0011 18.7 0.0 0.13 12.2 0.0 2.9 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 VBB32274.1 - 0.0022 18.0 0.0 1.2 9.2 0.0 2.7 2 1 0 2 2 2 2 RNA binding motif Colicin PF01024.19 VBB32274.1 - 0.0033 17.3 0.2 0.0068 16.3 0.2 1.4 1 0 0 1 1 1 1 Colicin pore forming domain Peptidase_M10 PF00413.24 VBB32275.1 - 3.9e-42 143.8 0.6 4.9e-42 143.5 0.6 1.1 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 VBB32275.1 - 5.3e-05 22.3 0.1 0.00018 20.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_3 PF13582.6 VBB32275.1 - 0.00047 20.7 1.4 0.00064 20.2 0.3 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 VBB32275.1 - 0.0013 18.4 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 VBB32275.1 - 0.0015 18.6 0.1 0.029 14.4 0.0 2.2 1 1 1 2 2 2 1 Peptidase family M54 Metallopep PF12044.8 VBB32275.1 - 0.0037 15.9 0.0 0.0057 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 VBB32275.1 - 0.0094 16.1 0.1 0.014 15.5 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 VBB32275.1 - 0.035 13.3 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 VBB32275.1 - 0.072 12.7 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) ubiquitin PF00240.23 VBB32275.1 - 0.13 12.0 0.2 16 5.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin family TPR_6 PF13174.6 VBB32277.1 - 0.0058 17.2 1.1 0.047 14.3 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB32277.1 - 0.22 11.8 4.1 1.1 9.6 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB32277.1 - 0.26 11.2 2.9 3.6 7.6 0.7 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 VBB32277.1 - 0.54 10.5 11.5 0.23 11.6 1.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32277.1 - 0.58 10.7 3.8 2 9.0 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 VBB32278.1 - 5.9e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 VBB32278.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 VBB32278.1 - 0.025 15.0 0.0 0.077 13.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 VBB32278.1 - 0.062 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain TTC5_OB PF16669.5 VBB32279.1 - 1.1e-32 112.1 0.1 1.7e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_1 PF00515.28 VBB32279.1 - 9.7e-11 41.0 6.3 8.2e-05 22.3 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB32279.1 - 4.9e-10 38.8 7.5 0.0021 18.0 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB32279.1 - 6e-08 32.3 1.3 0.054 13.2 0.0 4.1 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 VBB32279.1 - 8.6e-08 32.4 1.5 1.4 10.0 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB32279.1 - 2e-06 27.6 5.5 0.071 13.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB32279.1 - 3.6e-06 27.5 0.1 0.0033 18.0 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB32279.1 - 1.1e-05 25.5 0.9 0.19 12.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB32279.1 - 8.1e-05 22.8 1.2 0.053 13.8 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32279.1 - 0.0052 17.3 1.9 3 8.4 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 VBB32279.1 - 0.0061 16.5 0.6 0.52 10.5 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat FAT PF02259.23 VBB32279.1 - 0.027 13.7 1.7 0.17 11.1 0.5 2.5 1 1 1 2 2 2 0 FAT domain HEPN_Apea PF18739.1 VBB32279.1 - 0.14 12.6 1.0 0.5 10.8 0.3 2.2 2 0 0 2 2 2 0 Apea-like HEPN ANAPC3 PF12895.7 VBB32279.1 - 1.8 8.8 7.5 0.81 10.0 0.4 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HSP20 PF00011.21 VBB32280.1 - 1.3e-23 83.1 0.6 1.6e-23 82.8 0.6 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB32280.1 - 1.2e-05 24.7 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Big_6 PF17936.1 VBB32280.1 - 0.045 14.0 0.1 0.54 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial Ig domain ABC_membrane PF00664.23 VBB32283.1 - 6e-42 144.2 17.3 9.1e-42 143.6 17.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 VBB32283.1 - 3e-28 99.0 0.6 3.2e-27 95.7 0.6 2.4 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 VBB32283.1 - 8.9e-09 35.1 1.2 2.3e-06 27.2 0.1 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 VBB32283.1 - 5.1e-05 23.2 0.1 0.35 10.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 VBB32283.1 - 0.0011 19.0 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 VBB32283.1 - 0.0021 18.3 0.3 0.02 15.1 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 VBB32283.1 - 0.0022 18.4 0.0 0.26 11.7 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 VBB32283.1 - 0.0082 16.4 0.2 0.28 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 VBB32283.1 - 0.012 15.4 0.1 0.088 12.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 VBB32283.1 - 0.02 14.1 0.6 0.19 11.0 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin AAA_15 PF13175.6 VBB32283.1 - 0.021 14.5 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 VBB32283.1 - 0.03 13.5 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 VBB32283.1 - 0.037 14.5 1.3 4.3 7.8 0.1 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 VBB32283.1 - 0.054 13.5 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 VBB32283.1 - 0.075 12.9 0.4 0.18 11.7 0.1 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_29 PF13555.6 VBB32283.1 - 0.088 12.6 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 VBB32283.1 - 0.099 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC_ATPase PF09818.9 VBB32283.1 - 0.1 11.4 0.5 0.21 10.3 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Cation_efflux PF01545.21 VBB32283.1 - 0.13 12.0 5.9 0.24 11.1 5.9 1.4 1 0 0 1 1 1 0 Cation efflux family RBD PF02196.15 VBB32283.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain COX6C PF02937.15 VBB32283.1 - 0.77 9.9 2.9 2.1 8.5 0.1 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIc FH2 PF02181.23 VBB32285.1 - 4.7e-90 302.4 1.2 4.7e-90 302.4 1.2 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 VBB32285.1 - 4.1e-29 101.5 10.9 1.2e-14 54.3 0.9 2.9 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 VBB32285.1 - 1.8e-25 89.7 10.6 1.8e-25 89.7 10.6 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Spc7 PF08317.11 VBB32285.1 - 0.0057 15.6 14.3 0.013 14.4 14.3 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Cmc1 PF08583.10 VBB32285.1 - 0.076 13.0 0.6 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Baculo_PEP_C PF04513.12 VBB32285.1 - 0.29 11.2 2.0 1.1 9.4 2.0 2.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHD5 PF04420.14 VBB32285.1 - 0.41 10.5 5.3 0.62 9.9 4.1 2.0 1 1 0 1 1 1 0 CHD5-like protein GreA_GreB_N PF03449.15 VBB32285.1 - 0.92 9.7 8.9 3.6 7.8 7.0 3.1 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal SMN PF06003.12 VBB32285.1 - 1.8 7.7 11.5 4.8 6.4 11.5 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) JIP_LZII PF16471.5 VBB32285.1 - 2.1 8.6 14.6 2.2 8.5 5.3 2.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 VBB32285.1 - 4.4 6.5 8.0 11 5.1 8.0 1.7 1 0 0 1 1 1 0 TMPIT-like protein RVT_1 PF00078.27 VBB32286.1 - 0.0008 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5641 PF18701.1 VBB32287.1 - 2e-09 37.5 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) I-set PF07679.16 VBB32289.1 - 9.1e-25 86.6 0.4 2e-12 47.0 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB32289.1 - 2.9e-21 75.8 1.4 1.4e-09 38.4 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB32289.1 - 1.4e-16 60.5 0.1 8.2e-07 29.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 VBB32289.1 - 5.4e-15 55.3 0.1 1.7e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 VBB32289.1 - 9.8e-08 32.2 0.2 0.00024 21.3 0.0 3.6 3 1 1 4 4 4 1 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB32289.1 - 0.0001 22.6 0.0 0.0014 19.0 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 VBB32289.1 - 0.00031 20.3 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 VBB32289.1 - 0.0054 17.0 0.1 0.077 13.3 0.0 2.2 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 VBB32289.1 - 0.019 15.2 0.0 0.23 11.7 0.0 2.5 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 VBB32289.1 - 0.14 12.2 0.1 4.1 7.5 0.0 2.5 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DUF3309 PF11752.8 VBB32291.1 - 0.0017 18.4 0.3 0.0026 17.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3309) Baculo_11_kDa PF06143.11 VBB32291.1 - 0.042 13.4 0.8 0.068 12.8 0.8 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family UL45 PF05473.12 VBB32291.1 - 0.16 11.5 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Myosin_head PF00063.21 VBB32292.1 - 2.7e-93 313.4 0.5 3.2e-93 313.2 0.5 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DUF2075 PF09848.9 VBB32292.1 - 0.065 12.5 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 VBB32292.1 - 0.088 13.3 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 VBB32292.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 VBB32292.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB32292.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 VBB32292.1 - 0.21 11.5 0.2 0.71 9.8 0.2 1.8 2 0 0 2 2 2 0 NACHT domain Sema PF01403.19 VBB32294.1 - 1e-19 70.7 0.2 4.2e-17 62.1 0.0 2.5 2 1 1 3 3 3 2 Sema domain TSP_1 PF00090.19 VBB32294.1 - 3.1e-10 40.1 28.1 2.5e-07 30.8 10.9 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain Abhydrolase_1 PF00561.20 VBB32295.1 - 8.4e-08 32.2 0.2 0.001 18.8 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 VBB32295.1 - 9.4e-08 32.9 0.0 0.00015 22.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 VBB32295.1 - 0.016 14.5 0.0 1.1 8.5 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Pkinase PF00069.25 VBB32296.1 - 1e-44 152.9 0.0 1.8e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32296.1 - 1.5e-21 76.9 0.0 2.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32296.1 - 2.4e-07 30.4 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB32296.1 - 6.1e-05 22.0 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB32296.1 - 0.13 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 VBB32297.1 - 5.5e-26 91.5 0.0 8e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32297.1 - 4.5e-11 42.5 0.0 6.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32297.1 - 0.036 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1664 PF07889.12 VBB32298.1 - 0.014 15.5 2.5 0.027 14.5 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 VBB32298.1 - 0.033 14.2 9.8 0.042 13.9 9.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC106 PF15794.5 VBB32298.1 - 0.13 11.9 9.7 0.02 14.6 6.3 1.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Spc7 PF08317.11 VBB32298.1 - 0.18 10.7 10.6 0.2 10.5 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SirA PF10747.9 VBB32298.1 - 0.3 11.4 8.5 0.39 11.0 8.2 1.4 1 1 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Peptidase_C1 PF00112.23 VBB32300.1 - 1e-26 94.4 0.7 1.2e-26 94.2 0.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 VBB32300.1 - 0.00061 18.7 0.0 0.00082 18.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family PAXNEB PF05625.11 VBB32301.1 - 3.9e-60 203.9 0.0 4.8e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein MMR_HSR1 PF01926.23 VBB32302.1 - 1.9e-14 53.7 0.0 1.2e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 VBB32302.1 - 6.7e-08 32.2 0.1 1.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 VBB32302.1 - 2.4e-06 27.5 0.1 0.00011 22.2 0.1 2.1 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 VBB32302.1 - 4e-06 26.3 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 VBB32302.1 - 4.1e-05 23.2 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Septin PF00735.18 VBB32302.1 - 0.00049 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 VBB32302.1 - 0.006 16.7 0.5 1.7 8.7 0.2 2.4 1 1 1 2 2 2 2 Dynamin family G-alpha PF00503.20 VBB32302.1 - 0.021 14.0 0.1 0.33 10.1 0.0 2.3 2 1 1 3 3 3 0 G-protein alpha subunit ATP_bind_1 PF03029.17 VBB32302.1 - 0.052 13.3 0.0 0.99 9.1 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 VBB32302.1 - 0.077 12.0 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 VBB32302.1 - 0.12 12.6 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 VBB32302.1 - 0.12 12.9 0.2 0.35 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain Glutaredoxin PF00462.24 VBB32303.1 - 4.6e-19 68.4 0.4 7.2e-18 64.6 0.1 2.2 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 VBB32303.1 - 0.0019 18.6 0.5 0.015 15.7 0.0 2.3 2 1 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 VBB32303.1 - 0.024 15.1 1.1 0.049 14.1 0.1 1.9 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 VBB32303.1 - 0.025 14.6 0.2 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain GST_N_3 PF13417.6 VBB32303.1 - 0.062 13.7 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Corona_RPol_N PF06478.13 VBB32303.1 - 0.082 11.9 0.2 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus DSBA PF01323.20 VBB32303.1 - 0.1 12.3 0.3 0.77 9.5 0.1 2.2 1 1 0 2 2 2 0 DSBA-like thioredoxin domain ATP_bind_2 PF03668.15 VBB32304.1 - 0.04 13.2 0.2 0.51 9.6 0.1 2.1 1 1 0 2 2 2 0 P-loop ATPase protein family UPF0561 PF10573.9 VBB32304.1 - 0.38 10.9 6.4 0.23 11.6 2.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 TSP_1 PF00090.19 VBB32305.1 - 0.094 12.9 30.0 0.023 14.9 9.2 3.6 4 1 0 4 4 4 0 Thrombospondin type 1 domain Nnf1 PF03980.14 VBB32306.1 - 0.0075 16.6 0.8 2.4 8.6 0.1 2.7 2 0 0 2 2 2 2 Nnf1 Pilosulin PF17499.2 VBB32306.1 - 0.06 13.5 0.1 0.9 9.8 0.1 2.3 2 0 0 2 2 2 0 Ant venom peptides zf-C4pol PF14260.6 VBB32306.1 - 0.72 10.4 4.6 0.31 11.6 1.1 2.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Collagen PF01391.18 VBB32308.1 - 7.3e-21 73.7 112.5 4.7e-10 39.1 34.8 4.4 4 1 0 4 4 4 3 Collagen triple helix repeat (20 copies) SANT_DAMP1_like PF16282.5 VBB32309.1 - 0.029 14.6 0.9 0.066 13.4 0.9 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Hist_deacetyl PF00850.19 VBB32310.1 - 1.2e-47 162.9 0.0 1.4e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.32 VBB32311.1 - 6.8e-17 61.5 1.5 0.00012 22.8 0.0 5.2 4 1 1 5 5 5 4 WD domain, G-beta repeat B56 PF01603.20 VBB32313.1 - 1.4e-153 511.7 5.5 2.4e-120 402.3 2.1 2.6 2 1 1 3 3 3 2 Protein phosphatase 2A regulatory B subunit (B56 family) DDHD PF02862.17 VBB32313.1 - 0.031 14.5 0.2 0.057 13.6 0.2 1.4 1 0 0 1 1 1 0 DDHD domain Abhydrolase_3 PF07859.13 VBB32314.1 - 1e-05 25.5 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB32314.1 - 0.018 14.3 0.2 0.047 12.9 0.0 1.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 VBB32314.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 VBB32314.1 - 0.074 13.6 0.0 0.092 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF384 PF04064.13 VBB32315.1 - 2.9e-07 30.2 0.0 3.3e-06 26.8 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF384) T-box PF00907.22 VBB32316.1 - 4.6e-48 163.9 0.1 1.3e-47 162.4 0.0 1.7 2 0 0 2 2 2 1 T-box DUF2730 PF10805.8 VBB32317.1 - 0.34 11.0 6.5 0.3 11.2 2.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Phage_cap_E PF03864.15 VBB32318.1 - 0.027 13.7 0.1 0.033 13.4 0.1 1.1 1 0 0 1 1 1 0 Phage major capsid protein E DUF244 PF03112.14 VBB32318.1 - 0.06 13.2 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF STT3 PF02516.14 VBB32319.1 - 3e-154 514.6 42.5 1.7e-150 502.2 38.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit HAD_2 PF13419.6 VBB32319.1 - 4.2e-16 59.5 0.0 8.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB32319.1 - 4.6e-07 30.3 0.0 7.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 VBB32319.1 - 2.8e-06 27.3 0.0 6.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like B-block_TFIIIC PF04182.12 VBB32319.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Glyco_transf_49 PF13896.6 VBB32321.1 - 3e-51 174.7 6.0 8.4e-51 173.3 6.0 1.6 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF5420 PF17457.2 VBB32321.1 - 0.0085 16.0 0.2 0.019 14.8 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5420) Phage_NinH PF06322.11 VBB32321.1 - 0.021 14.7 0.2 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 Phage NinH protein Ribosomal_L1 PF00687.21 VBB32322.1 - 3.8e-47 160.7 2.2 4.7e-47 160.4 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family YacG PF03884.14 VBB32323.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG XRN_M PF17846.1 VBB32324.1 - 2.1e-91 307.1 5.6 2.1e-91 307.1 5.6 2.2 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 VBB32324.1 - 3.5e-74 249.3 0.0 5.5e-47 160.2 0.0 3.0 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 VBB32324.1 - 3.2e-29 102.1 0.1 1.4e-28 100.0 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 VBB32324.1 - 4e-12 46.1 0.0 8.7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Meiosis_expr PF15163.6 VBB32324.1 - 0.24 12.1 2.8 0.44 11.2 1.6 2.0 2 0 0 2 2 2 0 Meiosis-expressed DIRP PF06584.13 VBB32326.1 - 4.1e-35 120.2 0.0 1.6e-34 118.3 0.0 2.1 1 0 0 1 1 1 1 DIRP DUF4168 PF13767.6 VBB32326.1 - 0.14 13.4 0.1 0.4 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) zf-CHY PF05495.12 VBB32327.1 - 6e-11 42.7 8.6 6e-11 42.7 8.6 2.6 2 1 1 3 3 3 1 CHY zinc finger TMEM72 PF16054.5 VBB32327.1 - 6.4e-05 22.7 0.2 0.00011 21.9 0.2 1.4 1 0 0 1 1 1 1 Transmembrane protein family 72 Lar_restr_allev PF14354.6 VBB32327.1 - 0.073 13.5 4.5 0.088 13.2 0.2 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF4428 PF14471.6 VBB32327.1 - 0.2 11.6 0.2 0.2 11.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) Zn-ribbon_8 PF09723.10 VBB32327.1 - 1.2 9.3 8.3 9.7 6.4 1.8 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Complex1_LYR_2 PF13233.6 VBB32328.1 - 1.7e-16 60.7 1.1 7.9e-16 58.6 0.1 2.6 2 0 0 2 2 2 1 Complex1_LYR-like zf-HC5HC2H_2 PF13832.6 VBB32328.1 - 6.4e-09 35.9 9.8 2.1e-07 31.1 0.2 2.7 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 VBB32328.1 - 7.6e-09 35.7 13.0 4.5e-07 30.0 0.6 2.8 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD PF00628.29 VBB32328.1 - 2.7e-08 33.6 21.2 8.9e-08 31.9 13.0 2.6 2 0 0 2 2 2 2 PHD-finger Complex1_LYR PF05347.15 VBB32328.1 - 6.7e-07 29.3 0.1 2.7e-06 27.3 0.1 2.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ABC_tran_CTD PF16326.5 VBB32328.1 - 0.024 14.9 2.5 0.075 13.3 2.5 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain P4Ha_N PF08336.11 VBB32328.1 - 0.028 14.4 1.4 0.11 12.5 1.4 2.0 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4028 PF13220.6 VBB32328.1 - 0.035 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) C1_1 PF00130.22 VBB32328.1 - 0.091 12.7 25.9 0.032 14.1 8.8 3.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mei5_like PF17021.5 VBB32328.1 - 0.99 9.5 6.2 0.41 10.7 1.5 2.5 2 0 0 2 2 2 0 Putative double-strand recombination repair-like Prok-RING_1 PF14446.6 VBB32328.1 - 8.5 6.4 11.6 25 4.9 0.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_C1 PF00112.23 VBB32329.1 - 7e-71 238.8 3.9 2.2e-70 237.1 2.4 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 VBB32329.1 - 9e-09 35.7 0.5 1.8e-08 34.7 0.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 VBB32329.1 - 0.014 14.2 1.2 0.1 11.3 0.5 2.5 3 0 0 3 3 3 0 Peptidase C1-like family Rota_VP2 PF05087.12 VBB32329.1 - 0.047 11.8 0.1 0.058 11.5 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein YIF1 PF03878.15 VBB32330.1 - 1.5e-58 198.2 9.4 6.8e-46 156.7 0.2 2.2 1 1 1 2 2 2 2 YIF1 FA_desaturase PF00487.24 VBB32330.1 - 0.31 10.8 2.7 0.46 10.3 2.7 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Acyltransferase PF01553.21 VBB32331.1 - 1e-30 106.1 0.1 1.7e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase ALMT PF11744.8 VBB32332.1 - 0.17 10.7 6.1 0.21 10.4 6.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-H2C2_2 PF13465.6 VBB32334.1 - 3.6e-21 74.6 32.2 2.9e-08 33.8 1.9 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 VBB32334.1 - 3.8e-18 64.8 38.1 1.1e-05 25.6 1.4 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB32334.1 - 1.2e-14 53.7 35.3 0.00013 22.5 1.3 5.2 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 VBB32334.1 - 1.5e-09 37.6 26.3 0.023 14.7 2.2 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB32334.1 - 2.8e-07 30.6 18.7 0.0016 18.7 0.1 5.2 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 VBB32334.1 - 0.0002 21.3 22.8 0.064 13.3 2.6 4.9 2 1 3 5 5 4 2 BED zinc finger zf_UBZ PF18439.1 VBB32334.1 - 0.0033 17.0 11.5 0.99 9.1 0.2 4.4 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 VBB32334.1 - 0.0053 17.5 9.9 0.24 12.2 2.9 2.3 2 0 0 2 2 2 2 zinc-ribbon family C1_1 PF00130.22 VBB32334.1 - 0.0088 15.9 13.9 0.16 11.9 2.7 3.3 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.18 VBB32334.1 - 0.01 15.9 10.8 3 8.0 0.4 4.2 4 0 0 4 4 4 0 XPA protein N-terminal zf-met PF12874.7 VBB32334.1 - 0.012 16.0 23.3 0.38 11.2 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-AN1 PF01428.16 VBB32334.1 - 0.026 14.7 18.4 2.6 8.3 0.2 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger Ta0938 PF11494.8 VBB32334.1 - 0.029 14.7 1.1 0.35 11.2 0.0 2.6 1 1 1 2 2 2 0 Ta0938 Zn-ribbon_8 PF09723.10 VBB32334.1 - 0.033 14.3 14.6 0.8 9.9 4.0 3.6 1 1 3 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 VBB32334.1 - 0.04 13.8 17.7 1.5 8.8 1.3 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type HypA PF01155.19 VBB32334.1 - 0.041 13.9 8.0 0.36 10.9 1.6 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHCC PF10276.9 VBB32334.1 - 0.055 13.5 13.0 0.77 9.9 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger domain Prok-RING_1 PF14446.6 VBB32334.1 - 0.056 13.4 15.1 8.8 6.3 0.1 4.9 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 zf-C2H2_3rep PF18868.1 VBB32334.1 - 0.06 14.0 15.0 1.8 9.3 0.8 3.8 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 VBB32334.1 - 0.24 11.5 15.1 6.8 6.8 14.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon PyrI_C PF02748.15 VBB32334.1 - 0.34 10.8 10.9 2 8.4 0.1 4.2 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ADK_lid PF05191.14 VBB32334.1 - 0.39 10.7 11.2 0.91 9.6 1.3 3.4 1 1 3 4 4 4 0 Adenylate kinase, active site lid HNH_5 PF14279.6 VBB32334.1 - 0.39 10.6 11.0 12 5.8 0.2 4.2 3 1 0 3 3 3 0 HNH endonuclease HNH PF01844.23 VBB32334.1 - 0.68 10.1 15.8 4.7 7.5 0.7 4.4 4 0 0 4 4 4 0 HNH endonuclease zf-LYAR PF08790.11 VBB32334.1 - 0.78 9.7 21.9 2.3 8.2 0.4 5.1 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 VBB32334.1 - 0.81 9.8 11.5 22 5.3 0.1 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 VBB32334.1 - 1.2 9.2 10.3 2.2e+03 -1.4 10.3 3.9 1 1 0 1 1 1 0 CpXC protein YhfH PF14149.6 VBB32334.1 - 1.4 8.9 10.1 38 4.4 0.4 4.3 3 1 1 4 4 4 0 YhfH-like protein FYVE PF01363.21 VBB32334.1 - 1.8 8.8 20.1 61 3.9 5.3 3.4 1 1 1 2 2 2 0 FYVE zinc finger Zf_RING PF16744.5 VBB32334.1 - 2.5 8.3 13.8 12 6.2 0.3 4.2 1 1 3 4 4 4 0 KIAA1045 RING finger zinc-ribbons_6 PF07191.12 VBB32334.1 - 2.5 8.1 12.1 11 6.1 1.7 3.3 1 1 2 3 3 3 0 zinc-ribbons Arc_trans_TRASH PF08394.10 VBB32334.1 - 4.7 7.6 11.0 1.2 9.6 0.3 3.4 3 1 0 3 3 3 0 Archaeal TRASH domain Cys_rich_CPXG PF14255.6 VBB32334.1 - 4.7 7.2 7.9 6.5 6.7 0.9 3.2 3 1 0 3 3 2 0 Cysteine-rich CPXCG BolA PF01722.18 VBB32334.1 - 6.6 7.1 7.2 71 3.8 2.4 3.2 2 1 0 2 2 2 0 BolA-like protein zf-C2HE PF16278.5 VBB32334.1 - 7 7.2 20.7 3.2 8.3 3.0 4.3 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 VBB32334.1 - 8 6.7 14.5 1.7 8.8 0.9 3.6 2 1 2 4 4 4 0 Zic proteins zinc finger domain zf-MYND PF01753.18 VBB32334.1 - 8.6 6.5 14.2 0.61 10.2 3.4 3.4 2 2 0 2 2 2 0 MYND finger zf-C2H2_2 PF12756.7 VBB32334.1 - 9.4 6.6 22.2 7.2 7.0 0.5 4.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 VBB32334.1 - 9.9 6.5 20.3 3.3 8.1 10.2 3.5 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 VBB32335.1 - 1.5e-29 100.7 53.2 3.8e-06 27.0 0.6 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB32335.1 - 6.4e-29 99.1 51.8 1.8e-06 28.1 0.2 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB32335.1 - 1e-20 72.6 48.7 0.0007 20.2 0.7 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB32335.1 - 8.2e-11 41.9 30.0 0.027 14.7 0.7 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB32335.1 - 7.5e-09 35.4 40.8 0.00021 21.2 4.5 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-Di19 PF05605.12 VBB32335.1 - 0.00012 22.3 34.6 0.00029 21.1 7.2 4.1 1 1 4 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 VBB32335.1 - 0.00028 21.1 31.0 1.6 9.2 2.5 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 VBB32335.1 - 0.0035 18.0 15.8 0.81 10.5 0.9 3.2 2 1 1 3 3 3 2 zinc-ribbon family BolA PF01722.18 VBB32335.1 - 0.0088 16.3 2.0 2.3 8.6 0.0 2.7 2 1 0 2 2 2 1 BolA-like protein zf-C2H2_11 PF16622.5 VBB32335.1 - 0.016 15.0 0.1 0.016 15.0 0.1 5.1 6 0 0 6 6 5 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 VBB32335.1 - 0.023 14.7 1.6 0.023 14.7 1.6 4.3 3 1 0 3 3 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 VBB32335.1 - 0.03 14.5 25.0 0.043 13.9 1.0 4.4 3 1 1 4 4 4 0 Zinc ribbon domain Ta0938 PF11494.8 VBB32335.1 - 0.045 14.0 9.9 0.99 9.7 0.3 3.5 2 2 1 3 3 3 0 Ta0938 zf_UBZ PF18439.1 VBB32335.1 - 0.051 13.2 22.9 0.13 11.9 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 VBB32335.1 - 0.11 12.3 18.0 5.8 6.8 0.0 5.2 1 1 3 5 5 5 0 GAGA factor CpXC PF14353.6 VBB32335.1 - 0.12 12.4 0.1 0.12 12.4 0.1 4.4 1 1 2 4 4 3 0 CpXC protein DUF2709 PF10915.8 VBB32335.1 - 0.13 11.5 0.3 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2709) zf-Sec23_Sec24 PF04810.15 VBB32335.1 - 0.15 12.1 24.2 3.5 7.8 0.7 5.9 4 3 1 5 5 5 0 Sec23/Sec24 zinc finger zf-AN1 PF01428.16 VBB32335.1 - 0.24 11.6 30.9 2.5 8.3 1.4 6.2 6 0 0 6 6 6 0 AN1-like Zinc finger zf-CCHC_2 PF13696.6 VBB32335.1 - 0.33 10.8 13.7 6.1 6.8 0.5 4.4 4 0 0 4 4 4 0 Zinc knuckle zf-C2H2_9 PF16293.5 VBB32335.1 - 0.36 10.7 18.9 4.8 7.1 0.3 5.1 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 VBB32335.1 - 0.42 10.6 23.2 0.32 11.0 0.4 4.8 2 2 3 5 5 5 0 Adenylate kinase, active site lid zf-H2C2_5 PF13909.6 VBB32335.1 - 0.56 10.0 0.1 0.56 10.0 0.1 6.1 7 1 0 7 7 5 0 C2H2-type zinc-finger domain FYDLN_acid PF09538.10 VBB32335.1 - 0.85 10.3 14.1 36 5.1 0.8 5.0 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) PHD_4 PF16866.5 VBB32335.1 - 1.1 9.4 20.5 5.5 7.2 3.8 3.6 3 1 0 3 3 3 0 PHD-finger Zn_ribbon_SprT PF17283.2 VBB32335.1 - 1.2 9.1 21.9 0.63 10.0 5.1 4.1 3 2 0 3 3 3 0 SprT-like zinc ribbon domain zf_ZIC PF18366.1 VBB32335.1 - 1.7 8.8 22.1 1.3 9.2 0.2 5.1 3 2 2 5 5 5 0 Zic proteins zinc finger domain TF_Zn_Ribbon PF08271.12 VBB32335.1 - 1.9 8.1 0.0 1.9 8.1 0.0 5.3 5 1 0 5 5 4 0 TFIIB zinc-binding FYVE PF01363.21 VBB32335.1 - 2 8.6 33.4 0.089 12.9 11.3 3.6 1 1 1 3 3 3 0 FYVE zinc finger Acetone_carb_G PF08882.11 VBB32335.1 - 2 8.6 5.3 20 5.4 0.5 2.9 2 1 1 3 3 3 0 Acetone carboxylase gamma subunit XPA_N PF01286.18 VBB32335.1 - 2.1 8.5 22.0 17 5.5 0.1 5.9 6 0 0 6 6 6 0 XPA protein N-terminal zf-LYAR PF08790.11 VBB32335.1 - 5.1 7.1 24.3 1.1 9.2 0.2 5.4 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-MYST PF17772.1 VBB32335.1 - 6.8 6.4 19.3 4.6 6.9 0.1 4.8 4 2 1 5 5 5 0 MYST family zinc finger domain Rep_fac-A_C PF08646.10 VBB32335.1 - 6.8 6.4 12.4 1.2 8.9 0.2 3.0 1 1 3 4 4 4 0 Replication factor-A C terminal domain Arf PF00025.21 VBB32336.1 - 4.7e-77 257.4 0.1 5.2e-77 257.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB32336.1 - 8.2e-16 58.3 0.1 1.1e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB32336.1 - 5.4e-14 52.1 0.0 6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 VBB32336.1 - 5.8e-14 51.9 0.0 7.1e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 VBB32336.1 - 9.1e-13 48.1 0.8 4e-08 32.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 VBB32336.1 - 3.5e-12 46.2 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB32336.1 - 5.5e-05 23.2 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 VBB32336.1 - 0.016 14.6 1.0 0.019 14.3 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_18 PF13238.6 VBB32336.1 - 0.051 14.1 0.1 0.088 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain DFRP_C PF16543.5 VBB32338.1 - 9.6e-21 74.1 5.6 9.6e-21 74.1 5.6 4.0 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 VBB32338.1 - 9.8e-11 42.3 10.0 1.9e-08 34.9 1.7 3.6 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 VBB32338.1 - 4.4e-06 26.6 17.9 1.6e-05 24.8 6.3 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB32338.1 - 4e-05 23.3 10.1 0.00015 21.5 2.0 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 VBB32338.1 - 0.00042 20.2 1.3 0.00042 20.2 1.3 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 VBB32338.1 - 0.00099 19.3 1.1 0.22 11.7 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 VBB32338.1 - 0.076 13.5 10.6 2.9 8.5 4.5 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Got1 PF04178.12 VBB32339.1 - 6.9e-27 94.1 15.3 9.6e-27 93.7 15.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family FeoB_C PF07664.12 VBB32339.1 - 0.15 11.8 0.6 0.15 11.8 0.6 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Peptidase_S28 PF05577.12 VBB32340.1 - 4e-38 131.3 0.1 4.8e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Rootletin PF15035.6 VBB32341.1 - 1.9e-36 125.9 50.0 2e-34 119.3 22.8 9.5 5 2 4 10 10 10 4 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 VBB32341.1 - 0.00034 20.7 19.4 0.00034 20.7 19.4 14.5 6 3 7 13 13 13 5 TPR/MLP1/MLP2-like protein EzrA PF06160.12 VBB32341.1 - 0.0017 16.6 22.6 0.0017 16.6 22.6 10.0 5 2 3 9 9 8 3 Septation ring formation regulator, EzrA Tup_N PF08581.10 VBB32341.1 - 0.0018 18.5 10.5 0.0018 18.5 10.5 16.9 7 5 9 17 17 15 1 Tup N-terminal GAS PF13851.6 VBB32341.1 - 0.0018 17.6 12.0 0.0018 17.6 12.0 12.7 4 1 8 13 13 13 4 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 VBB32341.1 - 0.0025 17.3 19.6 0.0025 17.3 19.6 11.9 6 3 4 10 10 8 3 Tropomyosin AAA_13 PF13166.6 VBB32341.1 - 0.0029 16.3 32.4 0.0029 16.3 32.4 8.6 3 3 4 8 8 8 2 AAA domain Fib_alpha PF08702.10 VBB32341.1 - 0.0037 17.5 11.0 0.0037 17.5 11.0 13.8 7 4 9 16 16 15 3 Fibrinogen alpha/beta chain family APG6_N PF17675.1 VBB32341.1 - 0.004 17.7 17.4 0.004 17.7 17.4 15.6 4 2 12 16 16 14 4 Apg6 coiled-coil region SlyX PF04102.12 VBB32341.1 - 0.0063 17.1 1.5 0.0063 17.1 1.5 21.9 11 5 10 21 21 19 3 SlyX Spc7 PF08317.11 VBB32341.1 - 0.0082 15.1 232.4 0.016 14.1 10.0 12.6 3 1 8 13 13 13 9 Spc7 kinetochore protein PKcGMP_CC PF16808.5 VBB32341.1 - 0.014 15.3 0.2 0.014 15.3 0.2 12.6 13 2 0 13 13 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HJURP_C PF12347.8 VBB32341.1 - 0.1 12.6 1.9 17 5.6 0.1 3.5 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat MobC PF05713.11 VBB32341.1 - 0.33 11.5 16.6 0.54 10.8 0.5 6.6 6 0 0 6 6 5 0 Bacterial mobilisation protein (MobC) CENP-Q PF13094.6 VBB32341.1 - 6 7.0 0.0 0.067 13.4 12.2 14.7 5 1 10 15 15 11 0 CENP-Q, a CENPA-CAD centromere complex subunit MAD PF05557.13 VBB32341.1 - 7.3 4.8 233.4 0.048 12.0 45.2 9.1 4 2 5 9 9 9 0 Mitotic checkpoint protein Nefa_Nip30_N PF10187.9 VBB32342.1 - 8.5e-27 93.6 11.6 1.9e-26 92.4 11.6 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4407 PF14362.6 VBB32342.1 - 0.12 11.7 4.1 0.16 11.3 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 VBB32344.1 - 2.2e-43 147.9 0.2 4.7e-43 146.9 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 VBB32344.1 - 4.7e-13 48.6 0.1 8.8e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA PF00004.29 VBB32344.1 - 0.00071 20.0 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 VBB32344.1 - 0.019 14.2 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF5018 PF16410.5 VBB32344.1 - 0.037 12.7 0.0 0.079 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) AAA_assoc_2 PF16193.5 VBB32344.1 - 0.073 13.4 0.3 0.81 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA C-terminal domain Neur_chan_LBD PF02931.23 VBB32346.1 - 2.4e-41 141.5 0.6 2.4e-41 141.5 0.6 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB32346.1 - 4.4e-26 92.4 7.0 2.6e-20 73.5 1.1 2.8 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Aminotran_1_2 PF00155.21 VBB32347.1 - 2.3e-54 184.9 0.0 4.7e-54 183.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II zf-Tim10_DDP PF02953.15 VBB32347.1 - 3.3e-13 49.1 7.0 6.8e-13 48.1 7.0 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DegT_DnrJ_EryC1 PF01041.17 VBB32347.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 VBB32347.1 - 0.002 16.7 0.0 0.0036 15.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 VBB32347.1 - 0.0074 15.3 0.0 0.018 14.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 VBB32347.1 - 0.0095 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase PDZ PF00595.24 VBB32349.1 - 4.8e-48 161.4 8.1 4.7e-19 68.5 0.4 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 VBB32349.1 - 1.5e-27 95.2 8.0 6.6e-09 35.5 0.5 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 VBB32349.1 - 6.8e-21 74.4 7.1 9.2e-07 29.1 0.1 3.8 4 0 0 4 4 4 3 PDZ domain Tricorn_PDZ PF14685.6 VBB32349.1 - 3e-05 23.9 0.7 1.9 8.5 0.1 3.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain PT-HINT PF07591.11 VBB32349.1 - 0.0067 16.7 0.1 4.9 7.4 0.0 2.8 3 0 0 3 3 3 2 Pretoxin HINT domain PDZ_4 PF17816.1 VBB32349.1 - 0.043 14.2 0.0 16 6.0 0.0 3.2 3 0 0 3 3 3 0 PDZ domain Occludin_ELL PF07303.13 VBB32350.1 - 0.00085 20.0 42.8 0.047 14.4 6.3 4.5 3 1 1 4 4 4 4 Occludin homology domain TSNAXIP1_N PF15739.5 VBB32350.1 - 0.0022 18.4 10.6 0.0022 18.4 10.6 3.6 3 3 1 4 4 4 1 Translin-associated factor X-interacting N-terminus TMF_TATA_bd PF12325.8 VBB32350.1 - 0.0043 17.3 5.2 0.0043 17.3 5.2 4.5 2 2 2 4 4 4 1 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 VBB32350.1 - 0.37 10.1 28.4 0.048 13.0 14.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Acetyltransf_11 PF13720.6 VBB32350.1 - 3.3 8.2 17.8 1.4 9.4 0.1 4.4 3 1 2 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 2OG-FeII_Oxy_5 PF13759.6 VBB32351.1 - 0.0021 18.5 1.0 0.0043 17.4 1.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase NB-ARC PF00931.22 VBB32352.1 - 1.3e-13 50.8 0.0 2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 VBB32352.1 - 0.00019 21.8 0.0 0.00061 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain CARD PF00619.21 VBB32352.1 - 0.00026 21.0 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain Viral_helicase1 PF01443.18 VBB32352.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 VBB32352.1 - 0.018 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 VBB32352.1 - 0.038 14.1 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain S1 PF00575.23 VBB32354.1 - 6.9e-23 80.8 7.1 4.1e-08 33.4 0.1 10.8 10 1 0 10 10 10 4 S1 RNA binding domain DUF2187 PF09953.9 VBB32354.1 - 0.0087 16.0 1.6 23 5.1 0.0 4.4 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2187) RHD_DNA_bind PF00554.22 VBB32354.1 - 0.061 13.3 0.4 0.19 11.7 0.4 1.8 1 0 0 1 1 1 0 Rel homology DNA-binding domain ALS_ss_C PF10369.9 VBB32354.1 - 0.13 12.5 0.2 11 6.3 0.0 3.0 2 0 0 2 2 2 0 Small subunit of acetolactate synthase CsrA PF02599.16 VBB32354.1 - 0.29 11.1 9.5 0.38 10.7 0.1 3.9 3 0 0 3 3 3 0 Global regulator protein family G-gamma PF00631.22 VBB32355.1 - 8.1e-12 45.0 0.1 8.6e-12 44.9 0.1 1.0 1 0 0 1 1 1 1 GGL domain FaeA PF04703.12 VBB32355.1 - 0.023 15.1 0.1 0.03 14.7 0.1 1.2 1 0 0 1 1 1 0 FaeA-like protein Tugs PF17840.1 VBB32355.1 - 0.18 12.0 1.4 0.38 11.0 1.4 1.6 1 1 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF4217 PF13959.6 VBB32356.1 - 2.6e-15 56.4 0.0 9.5e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) TDP43_N PF18694.1 VBB32357.1 - 8.3e-18 64.0 0.0 1.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain DUF745 PF05335.13 VBB32357.1 - 0.0088 15.8 12.4 0.031 14.0 0.1 3.6 2 1 2 4 4 4 3 Protein of unknown function (DUF745) Fib_alpha PF08702.10 VBB32357.1 - 0.014 15.6 4.2 0.014 15.6 4.2 3.6 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 VBB32357.1 - 0.014 14.1 27.6 0.016 13.9 12.2 2.6 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 VBB32357.1 - 0.017 15.1 37.4 0.19 11.7 5.2 4.1 1 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 VBB32357.1 - 0.039 14.1 31.2 0.32 11.1 0.9 4.5 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Trans_reg_C PF00486.28 VBB32357.1 - 0.11 12.6 0.2 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Laminin_II PF06009.12 VBB32357.1 - 0.5 10.4 19.1 2.8 8.0 1.9 4.1 2 1 2 4 4 4 0 Laminin Domain II IL11 PF07400.11 VBB32357.1 - 0.73 9.5 7.0 0.28 10.8 2.3 2.5 1 1 1 2 2 2 0 Interleukin 11 Baculo_PEP_C PF04513.12 VBB32357.1 - 0.86 9.6 6.2 7.3 6.6 0.4 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 VBB32357.1 - 0.91 9.7 33.1 0.026 14.7 8.2 3.3 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 VBB32357.1 - 1.3 9.1 45.5 1.4 9.0 10.8 4.7 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus TLE_N PF03920.15 VBB32357.1 - 2.1 8.5 7.6 0.29 11.2 2.5 2.1 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF948 PF06103.11 VBB32357.1 - 3.4 8.0 5.7 22 5.4 0.0 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) SHE3 PF17078.5 VBB32357.1 - 3.6 7.2 39.0 0.031 14.0 17.8 2.9 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 CSN5_C PF18323.1 VBB32357.1 - 4.8 8.2 17.1 6.4 7.8 0.9 4.2 3 1 1 4 4 3 0 Cop9 signalosome subunit 5 C-terminal domain Sec34 PF04136.15 VBB32357.1 - 9 6.2 19.4 5.1 7.0 2.7 3.4 3 0 0 3 3 3 0 Sec34-like family NPV_P10 PF05531.12 VBB32357.1 - 9.5 6.8 9.8 60 4.2 0.3 4.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein NdhM PF10664.9 VBB32358.1 - 0.026 14.8 0.5 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M FANCI_HD1 PF14679.6 VBB32358.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FANCI helical domain 1 DNA_pol_phi PF04931.13 VBB32359.1 - 0.44 8.6 11.1 0.44 8.6 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 VBB32359.1 - 0.68 9.2 14.7 0.66 9.3 14.7 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 VBB32359.1 - 1.1 9.3 5.7 1.4 8.9 5.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 VBB32359.1 - 1.5 7.0 6.2 1.5 7.1 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 VBB32359.1 - 2.9 7.8 13.5 3 7.8 13.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM176 PF14851.6 VBB32359.1 - 4.8 6.8 6.0 4.4 7.0 5.4 1.3 1 1 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 VBB32359.1 - 7.5 5.6 17.9 7.4 5.6 17.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TTR-52 PF01060.23 VBB32361.1 - 1.7e-29 102.3 0.2 2.6e-29 101.7 0.2 1.3 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 VBB32361.1 - 0.0039 17.2 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain Transthyretin PF00576.21 VBB32361.1 - 0.14 12.8 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 HIUase/Transthyretin family Ribosomal_L50 PF10501.9 VBB32361.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Med8 PF10232.9 VBB32362.1 - 0.0024 17.5 0.1 0.0025 17.5 0.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DHHC PF01529.20 VBB32363.1 - 8.7e-06 25.9 9.7 0.0018 18.4 0.3 3.2 2 1 1 3 3 3 2 DHHC palmitoyltransferase Tim44 PF04280.15 VBB32364.1 - 1.8e-39 135.2 0.1 1.8e-39 135.2 0.1 2.0 2 0 0 2 2 2 1 Tim44-like domain DUF2228 PF10228.9 VBB32364.1 - 0.015 15.0 1.8 3.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) HMGL-like PF00682.19 VBB32364.1 - 0.051 13.1 2.4 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 HMGL-like Ribosomal_L28e PF01778.17 VBB32364.1 - 0.065 14.0 1.4 0.22 12.3 1.4 1.9 1 0 0 1 1 1 0 Ribosomal L28e protein family Prominin PF05478.11 VBB32364.1 - 0.086 10.8 3.3 0.18 9.8 3.3 1.4 1 0 0 1 1 1 0 Prominin AAA_lid_10 PF17872.1 VBB32364.1 - 0.19 11.8 3.0 0.46 10.7 3.0 1.6 1 0 0 1 1 1 0 AAA lid domain DUF1798 PF08807.10 VBB32364.1 - 0.3 11.2 4.8 3.2 7.9 0.5 2.8 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) RecG_N PF17190.4 VBB32364.1 - 0.37 11.5 7.1 5.9 7.7 5.9 3.1 1 1 1 2 2 2 0 RecG N-terminal helical domain MnmE_helical PF12631.7 VBB32364.1 - 0.71 10.0 5.0 1.6 8.8 3.3 2.0 2 0 0 2 2 2 0 MnmE helical domain Gal-bind_lectin PF00337.22 VBB32365.1 - 6e-09 35.5 0.1 6.4e-09 35.4 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin COesterase PF00135.28 VBB32366.1 - 1.3e-145 486.2 0.2 1.4e-145 486.1 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB32366.1 - 7.2e-10 39.1 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold TRAP-delta PF05404.12 VBB32366.1 - 0.07 12.7 0.7 0.31 10.5 0.7 2.0 1 1 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Pkinase PF00069.25 VBB32367.1 - 1.4e-53 182.0 0.3 1.2e-50 172.3 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32367.1 - 1.1e-19 70.7 0.1 6.1e-17 61.8 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB32367.1 - 0.028 14.4 0.2 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 VBB32367.1 - 0.18 11.1 0.3 0.32 10.3 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADK PF00406.22 VBB32369.1 - 1e-15 58.1 0.0 1.6e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 VBB32369.1 - 7e-07 29.8 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF5586 PF17824.1 VBB32369.1 - 0.0015 17.7 0.2 0.002 17.3 0.2 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5586) DUF4698 PF15769.5 VBB32369.1 - 0.0029 16.7 0.2 0.0043 16.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) Dpy-30 PF05186.13 VBB32369.1 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Zeta_toxin PF06414.12 VBB32369.1 - 0.0058 15.9 0.3 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin DUF5582 PF17819.1 VBB32369.1 - 0.012 16.1 0.2 0.031 14.7 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5582) KTI12 PF08433.10 VBB32369.1 - 0.036 13.5 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SCF PF02404.15 VBB32369.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor Use1 PF09753.9 VBB32369.1 - 0.13 11.9 0.5 0.19 11.4 0.5 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 WW PF00397.26 VBB32371.1 - 4.6e-11 42.6 2.3 3.6e-08 33.3 1.3 2.5 2 0 0 2 2 2 2 WW domain TraG_N PF07916.11 VBB32371.1 - 0.057 12.3 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region PAN_1 PF00024.26 VBB32372.1 - 9.1e-13 48.0 16.4 1.8e-06 27.8 4.0 2.9 2 0 0 2 2 2 2 PAN domain UQ_con PF00179.26 VBB32373.1 - 3e-30 104.7 0.1 6.2e-30 103.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 VBB32373.1 - 4.5e-05 23.3 0.2 0.00015 21.6 0.2 1.9 1 1 0 1 1 1 1 UEV domain UFC1 PF08694.11 VBB32373.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 zf-C4H2 PF10146.9 VBB32373.1 - 0.22 11.8 3.5 0.12 12.7 1.1 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein XRN_M PF17846.1 VBB32374.1 - 6.6e-154 513.1 0.5 1.2e-153 512.2 0.3 1.5 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 VBB32374.1 - 5.4e-102 340.4 0.0 1.1e-101 339.4 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CLIP1_ZNF PF16641.5 VBB32374.1 - 0.032 14.1 4.5 0.03 14.2 2.7 1.9 2 0 0 2 2 2 0 CLIP1 zinc knuckle HLH PF00010.26 VBB32375.1 - 2.5e-14 52.9 2.6 3.2e-14 52.6 0.8 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1283 PF06932.11 VBB32375.1 - 0.38 11.0 0.2 0.38 11.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) IL17 PF06083.11 VBB32377.1 - 0.014 15.8 2.1 0.014 15.8 2.1 2.0 2 0 0 2 2 2 0 Interleukin-17 Poty_PP PF08440.10 VBB32377.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Reg_prop PF07494.11 VBB32378.1 - 0.0097 16.0 0.0 0.062 13.6 0.0 2.5 1 0 0 1 1 1 1 Two component regulator propeller HECT PF00632.25 VBB32380.1 - 1.9e-60 204.9 0.0 3.3e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PABP PF00658.18 VBB32380.1 - 1.6e-15 57.0 0.1 4.3e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain PilW PF16074.5 VBB32380.1 - 0.026 14.5 0.0 0.089 12.8 0.0 1.9 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W Spore_III_AF PF09581.10 VBB32380.1 - 0.031 14.3 0.2 4.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) RETICULATA-like PF11891.8 VBB32380.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein RETICULATA-related C9orf72-like PF15019.6 VBB32381.1 - 9.8e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 C9orf72-like protein family SPA PF08616.10 VBB32381.1 - 0.11 12.5 0.1 0.44 10.5 0.1 1.9 1 1 1 2 2 2 0 Stabilization of polarity axis Thioredox_DsbH PF03190.15 VBB32382.1 - 9.9e-67 224.0 0.0 1.9e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 VBB32382.1 - 1.3e-09 38.1 0.0 5.1e-09 36.2 0.0 2.2 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_127 PF07944.12 VBB32382.1 - 3e-06 26.0 0.2 2.4e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 VBB32382.1 - 0.019 14.5 0.0 0.068 12.7 0.0 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 FBP_C PF16571.5 VBB32382.1 - 0.5 9.9 0.0 0.5 9.9 0.0 2.2 3 0 0 3 3 3 0 FBP C-terminal treble-clef zinc-finger Guanylate_cyc PF00211.20 VBB32384.1 - 1.1e-56 191.3 0.0 2.4e-56 190.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 VBB32384.1 - 4.9e-40 137.7 2.0 6.1e-39 134.1 2.0 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 VBB32384.1 - 3e-17 62.8 0.0 1.2e-16 60.8 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 VBB32384.1 - 3.8e-16 59.3 0.4 1e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Peripla_BP_6 PF13458.6 VBB32384.1 - 9.3e-06 25.5 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein HNOBA PF07701.14 VBB32384.1 - 0.0071 15.8 1.3 0.013 14.9 1.3 1.4 1 0 0 1 1 1 1 Heme NO binding associated DUF745 PF05335.13 VBB32384.1 - 0.037 13.7 0.3 0.066 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Glyco_transf_22 PF03901.17 VBB32385.1 - 5.7e-85 286.1 43.9 7.3e-85 285.7 43.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SUI1 PF01253.22 VBB32385.1 - 3e-16 59.7 0.3 7e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 Translation initiation factor SUI1 Globin PF00042.22 VBB32385.1 - 8.5e-09 36.0 0.1 1.8e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Globin Methyltr_RsmB-F PF01189.17 VBB32388.1 - 3.7e-16 59.4 2.1 8.2e-10 38.7 0.9 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DB PF01682.19 VBB32389.1 - 2.5e-14 53.4 9.3 2.5e-14 53.4 9.3 2.6 2 1 0 2 2 1 1 DB module CDC45 PF02724.14 VBB32389.1 - 0.00033 19.1 19.1 0.00038 18.9 19.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 VBB32389.1 - 0.00051 18.9 27.3 0.00078 18.3 27.3 1.4 1 0 0 1 1 1 1 Presenilin DUF4045 PF13254.6 VBB32389.1 - 0.012 15.3 22.7 0.014 15.1 22.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Tim54 PF11711.8 VBB32389.1 - 0.066 12.0 21.3 0.1 11.4 21.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 VBB32389.1 - 0.11 11.5 30.1 0.18 10.8 30.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2052 PF09747.9 VBB32389.1 - 0.15 12.2 30.7 0.24 11.5 30.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDRGK PF09756.9 VBB32389.1 - 0.19 11.3 34.3 0.35 10.4 34.3 1.5 1 0 0 1 1 1 0 DDRGK domain SID-1_RNA_chan PF13965.6 VBB32389.1 - 0.23 9.8 10.7 0.32 9.3 10.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.11 VBB32389.1 - 0.24 10.8 22.4 0.45 9.9 12.1 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PTPRCAP PF15713.5 VBB32389.1 - 0.27 11.5 29.2 0.54 10.5 29.2 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF5427 PF10310.9 VBB32389.1 - 0.3 10.0 38.0 0.4 9.6 38.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) eIF3_subunit PF08597.10 VBB32389.1 - 0.36 10.7 23.6 0.62 9.9 23.6 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF913 PF06025.12 VBB32389.1 - 0.45 9.5 14.7 0.67 8.9 14.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 VBB32389.1 - 0.48 8.4 21.9 0.63 8.1 21.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 VBB32389.1 - 0.52 8.5 52.4 0.63 8.2 52.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 VBB32389.1 - 0.52 8.4 29.9 0.65 8.1 29.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDM10 PF12519.8 VBB32389.1 - 0.64 8.8 21.2 0.88 8.4 21.2 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NARP1 PF12569.8 VBB32389.1 - 0.69 8.7 23.4 1.2 8.0 23.4 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp-B-Hydro_N PF05279.11 VBB32389.1 - 0.76 9.8 22.4 1.1 9.3 22.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4638 PF15472.6 VBB32389.1 - 0.84 9.3 19.4 1.2 8.8 19.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Paf1 PF03985.13 VBB32389.1 - 1.1 8.2 34.0 1.7 7.5 34.0 1.3 1 0 0 1 1 1 0 Paf1 Caldesmon PF02029.15 VBB32389.1 - 1.3 7.7 37.0 1.7 7.3 37.0 1.1 1 0 0 1 1 1 0 Caldesmon DUF4746 PF15928.5 VBB32389.1 - 1.5 8.1 22.1 2.4 7.5 22.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 VBB32389.1 - 2.1 8.1 36.2 0.81 9.5 33.9 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 VBB32389.1 - 2.1 5.3 28.4 2.5 5.1 28.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dicty_REP PF05086.12 VBB32389.1 - 2.7 5.9 19.8 3.3 5.6 19.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Membralin PF09746.9 VBB32389.1 - 2.9 6.8 19.5 4.6 6.2 19.5 1.4 1 0 0 1 1 1 0 Tumour-associated protein Zip PF02535.22 VBB32389.1 - 4.8 6.3 20.7 6.5 5.9 20.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EOS1 PF12326.8 VBB32389.1 - 7.1 6.5 23.0 1.4e+02 2.3 23.0 2.4 1 1 0 1 1 1 0 N-glycosylation protein VIR_N PF15912.5 VBB32389.1 - 9 5.8 22.4 15 5.1 22.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CPG4 PF15481.6 VBB32390.1 - 1.4e-05 25.6 6.8 0.0008 20.0 0.9 3.1 2 1 1 3 3 3 2 Chondroitin proteoglycan 4 DUF1397 PF07165.11 VBB32390.1 - 8.9e-05 22.0 3.6 0.01 15.3 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1397) DUF19 PF01579.18 VBB32390.1 - 0.013 15.4 2.8 0.042 13.7 2.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF2274 PF10038.9 VBB32390.1 - 0.24 11.9 0.3 20 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) TniQ PF06527.11 VBB32391.1 - 0.00012 22.8 1.4 0.00012 22.8 1.4 2.0 2 0 0 2 2 2 1 TniQ zf-H2C2_5 PF13909.6 VBB32391.1 - 0.0021 17.8 0.6 0.0021 17.8 0.6 2.7 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 VBB32391.1 - 0.015 15.5 6.7 0.04 14.2 6.7 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 VBB32391.1 - 0.046 14.6 1.4 0.046 14.6 1.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Thg1C PF14413.6 VBB32391.1 - 0.25 11.5 6.6 2.2 8.4 0.9 3.1 2 0 0 2 2 2 0 Thg1 C terminal domain DUF4520 PF15016.6 VBB32391.1 - 0.38 10.9 2.2 1 9.5 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) TRAM_LAG1_CLN8 PF03798.16 VBB32392.1 - 3.8e-38 131.2 21.6 3.8e-38 131.2 21.6 1.5 2 0 0 2 2 2 1 TLC domain TruB_N PF01509.18 VBB32393.1 - 4.6e-09 36.8 0.0 7.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 VBB32393.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Ribosomal_S4e PF00900.20 VBB32394.1 - 8.5e-33 112.1 0.2 3.1e-32 110.3 0.3 1.9 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 VBB32394.1 - 1.8e-23 81.9 0.0 3.1e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 VBB32394.1 - 4e-08 32.9 0.3 1.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 VBB32394.1 - 4.7e-06 26.3 0.5 1.7e-05 24.6 0.5 2.0 1 0 0 1 1 1 1 KOW motif RS4NT PF08071.12 VBB32394.1 - 0.0013 18.7 0.1 0.0041 17.2 0.1 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain Toxin_TOLIP PF00087.21 VBB32396.1 - 0.54 10.5 14.7 0.85 9.9 14.7 1.3 1 0 0 1 1 1 0 Snake toxin and toxin-like protein HtrL_YibB PF09612.10 VBB32399.1 - 4.5e-73 246.1 0.7 5.5e-73 245.8 0.7 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Rrp15p PF07890.12 VBB32400.1 - 1.5e-10 41.5 3.3 2e-10 41.1 3.3 1.4 1 1 0 1 1 1 1 Rrp15p Exonuc_X-T_C PF08411.10 VBB32401.1 - 0.048 12.8 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Exonuclease C-terminal BTB_3 PF16017.5 VBB32402.1 - 5.6e-43 145.4 0.0 1e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 VBB32402.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain LIM PF00412.22 VBB32403.1 - 1.1e-25 89.6 17.1 3.1e-13 49.7 5.6 2.1 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 VBB32403.1 - 0.0049 16.9 16.6 0.052 13.6 0.3 3.3 1 1 1 2 2 2 1 Double zinc ribbon zf-dskA_traR PF01258.17 VBB32403.1 - 0.096 12.6 0.4 0.096 12.6 0.4 3.8 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Yippee-Mis18 PF03226.14 VBB32403.1 - 0.17 12.1 8.7 50 4.2 5.9 3.5 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C3HC4_3 PF13920.6 VBB32403.1 - 4.1 7.4 20.5 13 5.8 10.0 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RecO_C PF02565.15 VBB32403.1 - 8.9 6.1 6.3 2.1 8.1 0.9 2.2 1 1 0 2 2 2 0 Recombination protein O C terminal Y_phosphatase PF00102.27 VBB32404.1 - 1.1e-29 103.7 0.0 1.3e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB32404.1 - 9.4e-07 28.7 0.1 1.6e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB32404.1 - 0.0089 16.0 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB32404.1 - 0.018 15.1 0.0 0.059 13.5 0.0 1.7 1 1 1 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.14 VBB32404.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF5600 PF18150.1 VBB32405.1 - 4.2e-45 152.7 0.8 1.2e-44 151.3 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 VBB32405.1 - 7.6e-18 64.4 0.0 4e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 VBB32405.1 - 1.2e-17 63.5 3.4 2.5e-17 62.4 3.4 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 VBB32405.1 - 2.6e-14 53.6 0.0 5.2e-13 49.4 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 VBB32405.1 - 1.6e-08 34.6 0.0 5.5e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 VBB32405.1 - 0.0008 18.8 0.6 0.0053 16.2 0.1 2.8 2 0 0 2 2 2 1 EF hand Roc PF08477.13 VBB32405.1 - 0.011 15.9 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 VBB32405.1 - 0.015 15.2 0.0 2.5 8.0 0.0 3.0 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 VBB32405.1 - 0.02 15.3 0.1 0.73 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 VBB32405.1 - 0.04 14.2 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain EF-hand_6 PF13405.6 VBB32405.1 - 0.042 13.8 0.1 0.4 10.7 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 VBB32405.1 - 0.055 13.3 4.6 3 7.7 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair cobW PF02492.19 VBB32405.1 - 0.16 11.5 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 VBB32405.1 - 1 9.8 3.4 28 5.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain SAM_1 PF00536.30 VBB32406.1 - 1.1e-14 54.6 0.3 2.5e-14 53.4 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB32406.1 - 1.8e-11 43.9 0.1 4.6e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sec8_exocyst PF04048.14 VBB32406.1 - 0.0004 20.3 0.8 0.00077 19.4 0.8 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Spc7 PF08317.11 VBB32406.1 - 0.0079 15.1 4.2 0.012 14.5 4.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Tweety PF04906.13 VBB32406.1 - 0.011 14.5 0.3 0.014 14.0 0.3 1.2 1 0 0 1 1 1 0 Tweety ECH_2 PF16113.5 VBB32406.1 - 0.015 14.8 0.4 0.018 14.6 0.4 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase KxDL PF10241.9 VBB32406.1 - 0.022 15.1 2.5 0.037 14.3 1.8 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein TMPIT PF07851.13 VBB32406.1 - 0.028 13.7 1.5 0.036 13.3 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein SesA PF17107.5 VBB32406.1 - 0.032 14.4 0.9 0.055 13.7 0.9 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases I_LWEQ PF01608.17 VBB32406.1 - 0.034 14.4 2.1 0.045 14.0 1.4 1.6 1 1 0 1 1 1 0 I/LWEQ domain Exonuc_VII_L PF02601.15 VBB32406.1 - 0.045 13.3 0.4 0.05 13.2 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3486 PF11985.8 VBB32406.1 - 0.048 14.1 0.4 0.07 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) UPF0449 PF15136.6 VBB32406.1 - 0.061 13.8 0.5 0.1 13.1 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Prefoldin_2 PF01920.20 VBB32406.1 - 0.068 13.1 3.3 0.1 12.6 1.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF3391 PF11871.8 VBB32406.1 - 0.073 13.6 0.2 0.1 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2381 PF09544.10 VBB32406.1 - 0.18 11.3 0.5 0.21 11.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Flagellin_N PF00669.20 VBB32406.1 - 0.28 11.3 2.5 0.43 10.7 2.5 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Cnn_1N PF07989.11 VBB32406.1 - 1.3 9.3 7.2 0.45 10.7 1.3 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1712 PF08217.11 VBB32407.1 - 4.8e-30 104.6 8.3 2.1e-22 79.4 0.6 2.9 2 1 1 3 3 3 3 Fungal domain of unknown function (DUF1712) A_deaminase PF00962.22 VBB32408.1 - 0.00077 18.9 0.2 0.36 10.1 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Neur_chan_LBD PF02931.23 VBB32409.1 - 4.4e-74 248.6 0.5 6e-74 248.1 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB32409.1 - 2.1e-45 155.6 1.8 2.8e-45 155.3 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 VBB32409.1 - 0.015 15.3 1.7 0.037 13.9 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Caps_synth_GfcC PF06251.11 VBB32410.1 - 0.00078 19.1 0.1 0.00087 19.0 0.1 1.0 1 0 0 1 1 1 1 Capsule biosynthesis GfcC BLOC1_2 PF10046.9 VBB32410.1 - 0.018 15.3 3.3 0.028 14.7 3.3 1.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNase_H2-Ydr279 PF09468.10 VBB32410.1 - 0.034 14.3 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain HDV_ag PF01517.18 VBB32410.1 - 0.12 12.2 0.4 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Latarcin PF10279.9 VBB32410.1 - 0.46 10.9 5.6 3.9 8.0 0.9 2.3 1 1 1 2 2 2 0 Latarcin precursor E1-E2_ATPase PF00122.20 VBB32412.1 - 3.4e-39 134.2 0.2 3.4e-39 134.2 0.2 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 VBB32412.1 - 1.9e-19 70.8 0.0 1.9e-09 38.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 VBB32412.1 - 1.3e-16 60.8 6.8 1.3e-16 60.8 6.8 2.9 2 1 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 VBB32412.1 - 3.6e-09 36.2 0.0 7.5e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 VBB32412.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 VBB32412.1 - 0.0038 17.0 0.4 2.8 7.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 VBB32412.1 - 0.13 12.0 14.4 0.0098 15.6 8.6 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Sec62 PF03839.16 VBB32412.1 - 2.6 7.5 5.3 0.21 11.1 0.2 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 AA_permease_2 PF13520.6 VBB32413.1 - 1.6e-25 89.8 23.0 2.1e-25 89.4 23.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 VBB32413.1 - 1.3e-07 30.7 23.0 6.5e-07 28.3 23.0 1.9 1 1 0 1 1 1 1 Amino acid permease Wzy_C PF04932.15 VBB32413.1 - 8.3 6.0 12.1 1.3 8.6 0.8 2.7 1 1 1 2 2 2 0 O-Antigen ligase NADH_dh_m_C1 PF15088.6 VBB32414.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial RNA_pol_Rpb4 PF03874.16 VBB32415.1 - 1.3e-24 86.9 4.7 1.8e-24 86.4 4.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Tfb4 PF03850.14 VBB32415.1 - 0.0059 16.1 0.1 0.0062 16.1 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 TetR_C_36 PF18598.1 VBB32415.1 - 0.037 14.0 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MIF4G_like_2 PF09090.11 VBB32415.1 - 0.051 13.1 2.9 0.81 9.1 0.2 2.0 2 0 0 2 2 2 0 MIF4G like EF-G-binding_N PF07299.11 VBB32415.1 - 0.14 12.7 2.2 0.32 11.6 0.8 2.3 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal DSPc PF00782.20 VBB32416.1 - 2.7e-35 121.1 0.0 4.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 VBB32416.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 VBB32416.1 - 0.00042 20.5 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate C2 PF00168.30 VBB32417.1 - 2.2e-58 194.9 0.3 2.6e-19 69.4 0.0 3.3 3 0 0 3 3 3 3 C2 domain DOCK-C2 PF14429.6 VBB32417.1 - 0.009 15.8 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins 2OG-FeII_Oxy_4 PF13661.6 VBB32417.1 - 0.16 12.6 0.0 0.43 11.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BTB PF00651.31 VBB32418.1 - 5.6e-11 42.7 0.0 1.7e-05 25.0 0.0 2.5 2 1 0 2 2 2 2 BTB/POZ domain zinc_ribbon_10 PF10058.9 VBB32418.1 - 0.11 12.2 6.0 0.27 11.0 6.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Patched PF02460.18 VBB32419.1 - 1.3e-105 354.3 7.0 1.6e-105 354.0 7.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB32419.1 - 0.035 13.9 7.9 0.097 12.5 7.9 1.9 1 1 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 VBB32419.1 - 0.35 10.2 14.3 0.65 9.4 14.3 1.4 1 0 0 1 1 1 0 Protein export membrane protein Microcin PF03526.13 VBB32419.1 - 0.74 9.7 5.5 4.9 7.0 0.1 3.1 2 1 1 3 3 3 0 Colicin E1 (microcin) immunity protein DUF4191 PF13829.6 VBB32419.1 - 5.5 6.3 9.9 3.3 7.0 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Neurensin PF14927.6 VBB32420.1 - 4.8e-16 58.7 0.0 5.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Neurensin DUF3185 PF11381.8 VBB32420.1 - 0.0023 17.9 0.2 0.0038 17.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3185) DUF3665 PF12427.8 VBB32420.1 - 3.2 7.5 7.7 1.1 9.0 0.8 2.3 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Cupin_8 PF13621.6 VBB32421.1 - 1.7e-20 73.8 0.7 3.7e-20 72.7 0.1 1.7 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 VBB32421.1 - 1.7e-08 34.3 0.0 3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 VBB32421.1 - 5.4e-07 30.0 0.2 4.3e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase GPI PF06560.11 VBB32421.1 - 0.0021 17.4 0.0 0.0059 15.9 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate isomerase (GPI) Cupin_1 PF00190.22 VBB32421.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 VBB32421.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain C6 PF01681.17 VBB32422.1 - 0.0048 17.4 2.5 0.0062 17.0 2.5 1.3 1 0 0 1 1 1 1 C6 domain Erf4 PF10256.9 VBB32423.1 - 2.6e-28 98.5 0.0 3.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Pkinase PF00069.25 VBB32424.1 - 3.8e-72 242.8 0.0 6.4e-72 242.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32424.1 - 1.1e-44 152.7 0.0 1.8e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 VBB32424.1 - 5.7e-24 84.2 0.0 1.8e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 VBB32424.1 - 3.3e-06 26.7 0.0 0.00012 21.5 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 VBB32424.1 - 7.2e-06 25.0 0.0 1.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB32424.1 - 0.0031 16.9 0.1 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 VBB32424.1 - 0.033 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 VBB32424.1 - 0.11 12.3 0.1 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RRM_5 PF13893.6 VBB32425.1 - 1.6e-10 40.6 0.4 5.5e-08 32.4 0.3 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 VBB32425.1 - 0.038 14.2 0.9 0.3 11.3 0.3 2.3 1 1 1 2 2 2 0 RRM-like domain SOBP PF15279.6 VBB32425.1 - 1.6 9.3 20.2 0.22 12.1 15.9 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Cyt-b5 PF00173.28 VBB32426.1 - 8.2e-11 41.9 0.0 1.5e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 VBB32427.1 - 1.2e-69 234.7 0.0 2.8e-69 233.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32427.1 - 6.5e-29 101.0 0.0 9.7e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 VBB32427.1 - 4.1e-05 24.0 0.0 9.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 VBB32427.1 - 0.0013 17.6 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 VBB32427.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB32427.1 - 0.06 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Stirrup PF09061.6 VBB32427.1 - 0.063 13.5 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Stirrup YccJ PF13993.6 VBB32427.1 - 0.14 12.5 0.8 0.3 11.4 0.4 1.8 1 1 0 1 1 1 0 YccJ-like protein RGS PF00615.19 VBB32428.1 - 3.8e-06 27.1 0.1 2.4e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Methyltransf_31 PF13847.6 VBB32429.1 - 5.9e-15 55.4 0.0 8.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB32429.1 - 5.4e-14 52.7 0.0 1e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB32429.1 - 2.3e-13 50.6 0.0 4.7e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB32429.1 - 2.1e-09 38.0 0.0 3.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB32429.1 - 3e-09 36.9 0.0 5.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB32429.1 - 1.1e-08 34.7 0.2 5.1e-08 32.5 0.2 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 VBB32429.1 - 4.4e-06 26.3 0.0 3.9e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 VBB32429.1 - 0.0031 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 VBB32429.1 - 0.018 14.3 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 VBB32429.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 VBB32429.1 - 0.028 13.7 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase domain adh_short PF00106.25 VBB32430.1 - 1.9e-18 66.6 0.2 2e-16 60.1 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB32430.1 - 2.7e-15 56.6 0.1 4.3e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB32430.1 - 8.6e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 VBB32430.1 - 0.00015 21.2 0.1 0.00096 18.6 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 VBB32430.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_holin_6_1 PF09682.10 VBB32430.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Shikimate_DH PF01488.20 VBB32430.1 - 0.051 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF5461 PF17545.2 VBB32430.1 - 0.079 13.3 0.4 0.19 12.0 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5461) Wax2_C PF12076.8 VBB32430.1 - 0.079 12.7 1.0 2.1 8.1 0.0 3.2 3 2 2 5 5 5 0 WAX2 C-terminal domain CTD_bind PF04818.13 VBB32431.1 - 1.3e-13 51.5 0.1 7.2e-13 49.1 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 VBB32431.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Activator_LAG-3 PF11498.8 VBB32431.1 - 0.00098 18.2 30.8 0.0018 17.4 30.8 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 SOBP PF15279.6 VBB32431.1 - 0.0014 19.3 16.1 0.0014 19.3 16.1 2.3 2 0 0 2 2 2 1 Sine oculis-binding protein TERB2 PF15101.6 VBB32431.1 - 0.026 14.6 6.7 0.058 13.4 6.7 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 HWE_HK PF07536.14 VBB32431.1 - 0.56 11.0 10.1 24 5.7 10.2 2.7 2 0 0 2 2 2 0 HWE histidine kinase Exonuc_VII_L PF02601.15 VBB32431.1 - 2.4 7.6 15.9 4.5 6.8 15.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit KAsynt_C_assoc PF16197.5 VBB32431.1 - 5.2 7.6 6.7 12 6.4 6.7 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension GREB1 PF15782.5 VBB32431.1 - 7.9 3.5 13.1 10 3.1 13.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gelsolin PF00626.22 VBB32433.1 - 1.5e-28 98.5 0.0 6.6e-13 48.4 0.0 3.1 3 0 0 3 3 3 2 Gelsolin repeat Voltage_CLC PF00654.20 VBB32434.1 - 4.2e-30 105.2 4.0 4.2e-30 105.2 4.0 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel Syntaxin PF00804.25 VBB32436.1 - 2.1e-63 213.6 9.5 3.4e-63 213.0 9.5 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 VBB32436.1 - 4.7e-12 45.7 3.4 1.7e-11 43.9 0.7 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 VBB32436.1 - 4.4e-11 43.0 1.6 4.4e-11 43.0 1.6 2.7 2 1 0 2 2 2 1 Syntaxin-like protein DUF4703 PF15775.5 VBB32436.1 - 0.00077 19.3 0.2 0.0018 18.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4703) Syntaxin-6_N PF09177.11 VBB32436.1 - 0.026 15.1 4.5 0.036 14.6 0.6 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 VBB32436.1 - 0.032 14.5 5.2 0.91 9.8 0.3 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Lzipper-MIP1 PF14389.6 VBB32436.1 - 0.046 14.0 0.3 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF2508 PF10704.9 VBB32436.1 - 0.087 13.0 1.2 0.67 10.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) MCPsignal PF00015.21 VBB32436.1 - 0.18 11.6 5.7 0.74 9.6 0.3 3.0 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.12 VBB32436.1 - 0.3 11.4 4.9 80 3.6 0.0 4.1 4 0 0 4 4 4 0 Proteins of 100 residues with WXG CAP_N PF01213.19 VBB32436.1 - 0.39 10.1 4.4 1.1 8.7 1.3 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal YabA PF06156.13 VBB32436.1 - 1.1 10.0 7.3 3.7 8.2 0.4 2.8 2 1 0 2 2 2 0 Initiation control protein YabA YtxH PF12732.7 VBB32436.1 - 1.5 9.4 4.6 6.1 7.4 1.0 3.0 2 1 0 2 2 2 0 YtxH-like protein DUF148 PF02520.17 VBB32436.1 - 3.6 7.7 7.1 0.51 10.5 1.6 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF148 Fib_alpha PF08702.10 VBB32436.1 - 3.8 7.7 11.2 6.1 7.0 1.3 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 VBB32436.1 - 4.1 8.2 6.8 3.3 8.5 0.5 2.8 2 1 0 2 2 2 0 Occludin homology domain RecG_N PF17190.4 VBB32436.1 - 7.2 7.4 7.6 1.9 9.3 1.2 3.0 2 1 1 3 3 3 0 RecG N-terminal helical domain Fez1 PF06818.15 VBB32436.1 - 7.4 7.0 12.1 0.97 9.9 0.3 2.7 2 1 0 2 2 2 0 Fez1 EB PF01683.18 VBB32437.1 - 5e-95 311.7 172.3 2.6e-12 46.8 14.0 10.2 9 1 1 10 10 10 10 EB module Dickkopf_N PF04706.12 VBB32437.1 - 0.021 15.3 129.5 0.058 13.9 2.9 12.0 9 4 2 11 11 11 0 Dickkopf N-terminal cysteine-rich region DUF5356 PF17309.2 VBB32438.1 - 1.9e-39 134.7 1.7 2.1e-39 134.6 1.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5356) DNA_pol_D_N PF18018.1 VBB32439.1 - 2.1e-28 99.0 0.0 2.7e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DEAD PF00270.29 VBB32440.1 - 2.7e-47 160.8 0.0 4.9e-46 156.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB32440.1 - 9.2e-30 103.2 0.0 4.3e-29 101.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB32440.1 - 0.00057 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 VBB32440.1 - 0.0037 17.5 0.0 0.083 13.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain zf-CCHC PF00098.23 VBB32440.1 - 0.086 12.9 2.0 0.15 12.2 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Roughex PF06020.11 VBB32441.1 - 0.57 9.2 5.0 1 8.4 5.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Pkinase PF00069.25 VBB32442.1 - 3.6e-26 92.1 0.0 4.1e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32442.1 - 2.4e-08 33.6 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB32442.1 - 0.00088 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4988 PF16378.5 VBB32443.1 - 2 8.0 7.5 2.4 7.8 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function RGM_C PF06534.13 VBB32444.1 - 1.2e-40 138.9 0.1 1.8e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 VBB32444.1 - 2.2e-28 99.5 0.7 4.9e-28 98.4 0.7 1.6 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus DUF4962 PF16332.5 VBB32445.1 - 0.00012 20.7 5.2 0.00015 20.4 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) DUF5518 PF17647.1 VBB32445.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) Protocadherin PF08374.11 VBB32445.1 - 0.36 10.8 8.1 0.83 9.6 2.3 2.6 1 1 0 2 2 2 0 Protocadherin Orf78 PF06024.12 VBB32445.1 - 0.63 10.4 4.4 0.75 10.1 0.1 2.4 1 1 1 2 2 2 0 Orf78 (ac78) Peptidase_M10 PF00413.24 VBB32447.1 - 3.9e-45 153.5 0.0 5.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 VBB32447.1 - 1.7e-10 41.0 0.0 4.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_5 PF13688.6 VBB32447.1 - 4.4e-06 27.0 0.1 9.4e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 VBB32447.1 - 0.0001 22.0 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 VBB32447.1 - 0.00099 19.1 0.2 0.0024 17.8 0.1 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 VBB32447.1 - 0.0032 18.0 0.6 0.19 12.2 0.1 2.8 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 VBB32447.1 - 0.0041 16.7 1.6 0.15 11.6 0.3 2.6 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) Hemopexin PF00045.19 VBB32447.1 - 0.0065 16.4 0.1 0.42 10.6 0.1 2.7 2 0 0 2 2 2 1 Hemopexin Peptidase_M54 PF07998.11 VBB32447.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 VBB32447.1 - 0.012 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 VBB32447.1 - 0.035 12.7 0.0 0.06 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family HD_4 PF13328.6 VBB32448.1 - 1.6e-23 83.2 0.3 3.4e-23 82.1 0.3 1.5 1 1 0 1 1 1 1 HD domain HD PF01966.22 VBB32448.1 - 1.8e-06 28.2 0.7 3.4e-06 27.3 0.3 1.7 2 0 0 2 2 2 1 HD domain HAD_2 PF13419.6 VBB32448.1 - 0.02 15.0 0.2 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SAM_PNT PF02198.16 VBB32448.1 - 0.064 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3562 PF12085.8 VBB32448.1 - 0.23 11.1 0.1 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) HECT PF00632.25 VBB32449.1 - 3.3e-82 276.4 1.2 4.1e-82 276.1 1.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RRN7 PF11781.8 VBB32450.1 - 2.5e-05 23.8 4.7 2.5e-05 23.8 4.7 1.9 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Lung_7-TM_R PF06814.13 VBB32451.1 - 7.8e-09 35.2 0.1 1.1e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor Ras PF00071.22 VBB32452.1 - 1.7e-54 183.8 0.3 2.2e-54 183.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB32452.1 - 2.1e-20 73.1 0.0 3.6e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB32452.1 - 6e-10 38.9 0.0 7.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB32452.1 - 2.9e-06 27.3 0.5 0.0031 17.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 VBB32452.1 - 7.7e-06 25.6 0.0 2.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 VBB32452.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 VBB32452.1 - 0.011 15.5 1.3 0.02 14.7 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 VBB32452.1 - 0.027 14.0 0.4 0.1 12.1 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 VBB32452.1 - 0.037 13.6 0.4 0.99 8.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 VBB32452.1 - 0.042 13.2 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB32452.1 - 0.045 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PGI PF00342.19 VBB32452.1 - 0.19 10.3 2.3 4 5.9 0.1 2.0 2 0 0 2 2 2 0 Phosphoglucose isomerase CNRIP1 PF15043.6 VBB32453.1 - 9.1e-47 158.5 0.0 1.1e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 SFTA2 PF15210.6 VBB32453.1 - 0.049 13.6 0.0 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 Surfactant-associated protein 2 Receptor_2B4 PF11465.8 VBB32453.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 zf-BED PF02892.15 VBB32454.1 - 5.8e-10 39.0 0.2 1.2e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 BED zinc finger Cation_ATPase_C PF00689.21 VBB32455.1 - 4.3e-33 114.6 2.5 7.5e-33 113.8 2.5 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 VBB32455.1 - 2.3e-13 50.9 0.1 1e-06 29.2 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 VBB32455.1 - 5.9e-13 48.7 0.1 1.2e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 VBB32455.1 - 0.00077 19.3 0.6 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NUDIX PF00293.28 VBB32456.1 - 4e-12 46.3 0.0 6.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain HOOK PF05622.12 VBB32457.1 - 1e-90 304.9 77.6 1.3e-90 304.6 77.6 1.0 1 0 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 VBB32457.1 - 1.5 8.9 97.1 0.1 12.7 17.1 6.9 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NOA36 PF06524.12 VBB32460.1 - 0.48 9.7 27.9 0.52 9.6 27.9 1.1 1 0 0 1 1 1 0 NOA36 protein Utp14 PF04615.13 VBB32460.1 - 2.2 6.7 13.0 2.3 6.7 13.0 1.0 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 VBB32460.1 - 2.9 6.1 15.3 2.9 6.1 15.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 VBB32460.1 - 4.8 6.2 30.7 4.8 6.2 30.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 VBB32460.1 - 7.2 5.8 13.8 6.8 5.9 13.8 1.0 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 VBB32460.1 - 7.6 6.0 15.7 8.3 5.9 15.7 1.0 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 VBB32460.1 - 9.5 4.2 29.4 9.7 4.2 29.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C37 PF05416.12 VBB32461.1 - 0.27 9.7 2.9 0.38 9.2 2.9 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase KTI12 PF08433.10 VBB32462.1 - 1.7e-65 221.2 0.1 3.4e-65 220.2 0.1 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 VBB32462.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain Mitofilin PF09731.9 VBB32463.1 - 4.8e-109 366.0 33.5 4.8e-109 366.0 33.5 1.3 1 1 1 2 2 2 1 Mitochondrial inner membrane protein DUF4366 PF14283.6 VBB32463.1 - 0.0096 16.0 2.4 0.036 14.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) 7tm_1 PF00001.21 VBB32464.1 - 2.9e-66 223.5 11.2 5.6e-66 222.6 11.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB32464.1 - 3.1e-07 30.0 10.2 3.1e-07 30.0 10.2 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 VBB32464.1 - 1.8e-05 24.7 10.5 0.00019 21.2 6.8 3.0 2 1 1 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 VBB32464.1 - 0.00043 20.0 12.0 0.00043 20.0 12.0 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1077 PF06417.12 VBB32464.1 - 0.31 11.0 3.9 1 9.4 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1077) DUF1700 PF08006.11 VBB32464.1 - 6.1 6.3 21.0 1.6 8.2 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) zf-H2C2_2 PF13465.6 VBB32466.1 - 8.4e-08 32.3 0.5 2.3e-07 30.9 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 VBB32466.1 - 0.065 13.7 0.1 0.065 13.7 0.1 2.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF4764 PF15961.5 VBB32466.1 - 0.067 11.9 0.3 0.1 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2HE PF16278.5 VBB32466.1 - 0.15 12.5 0.9 0.3 11.5 0.9 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 VBB32466.1 - 0.35 11.8 0.2 0.35 11.8 0.2 2.2 2 1 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.29 VBB32467.1 - 5e-44 150.2 0.0 7.9e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB32467.1 - 6.2e-32 110.2 0.2 2.5e-31 108.3 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 VBB32467.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 VBB32467.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UTP25 PF06862.12 VBB32467.1 - 0.075 11.8 0.2 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 VBB32467.1 - 0.18 12.1 0.0 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain LIM PF00412.22 VBB32468.1 - 1.8e-21 76.1 28.1 8.7e-11 41.9 11.6 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 VBB32468.1 - 1.4e-18 66.4 4.7 2.6e-18 65.6 4.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB32468.1 - 1.6e-05 24.7 0.2 3.2e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 VBB32468.1 - 0.029 13.8 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pkinase PF00069.25 VBB32469.1 - 8.4e-61 205.6 0.0 1.4e-59 201.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32469.1 - 5.1e-31 107.9 0.1 8.1e-26 90.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase RGS PF00615.19 VBB32469.1 - 9.7e-10 38.8 1.2 3e-09 37.2 1.2 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 VBB32469.1 - 7.1e-07 28.8 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB32469.1 - 0.00016 20.6 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase HLH PF00010.26 VBB32470.1 - 3.9e-17 62.0 1.9 5.8e-17 61.4 1.9 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain I-set PF07679.16 VBB32471.1 - 6.4e-189 612.7 0.0 2.5e-16 59.5 0.0 13.1 13 0 0 13 13 13 13 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB32471.1 - 5.6e-181 587.6 13.0 3.3e-16 59.6 0.0 13.2 13 0 0 13 13 13 13 Immunoglobulin domain Ig_2 PF13895.6 VBB32471.1 - 5.2e-136 443.3 1.9 4.3e-12 46.2 0.0 13.1 13 0 0 13 13 13 13 Immunoglobulin domain ig PF00047.25 VBB32471.1 - 1.9e-121 396.5 0.0 6.8e-10 39.0 0.0 13.4 13 0 0 13 13 13 13 Immunoglobulin domain V-set PF07686.17 VBB32471.1 - 2.1e-58 195.2 29.2 2.5e-05 24.4 0.0 23.3 14 11 4 18 18 18 14 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB32471.1 - 1.2e-33 115.0 7.5 5.9e-05 23.1 0.0 12.3 13 1 0 13 13 13 6 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 VBB32471.1 - 4.2e-33 113.6 0.0 0.0017 18.7 0.0 12.9 13 0 0 13 13 13 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 VBB32471.1 - 3.9e-31 106.4 0.0 0.021 14.4 0.0 11.7 13 0 0 13 13 13 7 Immunoglobulin domain Ig_4 PF16680.5 VBB32471.1 - 6.2e-26 90.5 0.0 0.02 15.1 0.0 12.3 13 0 0 13 13 13 4 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 VBB32471.1 - 8.9e-22 77.0 1.5 0.0099 15.9 0.0 11.6 12 0 0 12 12 12 3 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB32471.1 - 2.2e-15 56.5 0.0 0.29 11.2 0.0 9.1 9 1 0 9 9 8 3 C17orf99 Ig domain C1-set PF07654.15 VBB32471.1 - 2.9e-11 43.6 0.9 0.37 11.2 0.0 9.3 9 0 0 9 9 9 2 Immunoglobulin C1-set domain BiPBP_C PF06832.12 VBB32471.1 - 1e-08 35.1 0.0 3.5 7.7 0.0 7.2 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 VBB32471.1 - 8.2e-06 26.0 0.9 72 3.6 0.0 7.8 9 0 0 9 9 8 0 Natural killer cell receptor 2B4 C2-set PF05790.15 VBB32471.1 - 0.00012 22.2 0.0 7.3 6.9 0.0 7.4 10 0 0 10 10 9 1 Immunoglobulin C2-set domain Herpes_gE PF02480.16 VBB32471.1 - 0.00025 19.9 0.6 14 4.3 0.0 5.6 7 1 0 7 7 7 0 Alphaherpesvirus glycoprotein E PKD_3 PF16820.5 VBB32471.1 - 0.0065 16.2 0.2 5.2 6.9 0.0 4.6 5 0 0 5 5 5 1 PKD-like domain Herpes_gI PF01688.17 VBB32471.1 - 0.085 12.8 0.1 37 4.2 0.0 4.0 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I RhoGEF PF00621.20 VBB32472.1 - 6.6e-25 88.4 0.0 6.6e-25 88.4 0.0 2.7 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 VBB32472.1 - 1.9e-05 25.1 0.7 5.5e-05 23.6 0.7 1.8 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 VBB32472.1 - 0.0028 17.9 1.0 0.0099 16.1 1.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain RRM_7 PF16367.5 VBB32473.1 - 2.4e-10 40.4 0.0 5.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 VBB32473.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CEBP_ZZ PF16366.5 VBB32474.1 - 6.8e-17 61.5 5.6 6.8e-17 61.5 5.6 2.1 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 VBB32474.1 - 1.9e-09 37.2 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB32474.1 - 1e-08 35.2 0.1 1.1e-05 25.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif Baculo_IE-1 PF05290.11 VBB32474.1 - 0.0077 16.2 2.2 0.0083 16.1 0.7 1.8 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Coq4 PF05019.13 VBB32475.1 - 1.2e-58 198.0 0.0 5e-50 169.9 0.0 2.1 1 1 1 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 EGF_3 PF12947.7 VBB32476.1 - 1.5e-07 31.5 9.1 1.5e-07 31.5 9.1 2.9 2 1 1 3 3 3 1 EGF domain EGF_CA PF07645.15 VBB32476.1 - 7.4e-07 29.3 10.5 7.4e-07 29.3 10.5 2.8 3 0 0 3 3 3 1 Calcium-binding EGF domain EGF PF00008.27 VBB32476.1 - 2.2e-05 24.6 30.5 0.00025 21.3 8.5 2.9 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.7 VBB32476.1 - 4.9e-05 23.2 18.6 0.0023 17.8 7.1 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_2 PF07974.13 VBB32476.1 - 0.0003 21.1 33.6 0.0012 19.2 17.8 3.0 2 1 0 2 2 2 2 EGF-like domain EGF_MSP1_1 PF12946.7 VBB32476.1 - 0.0034 17.4 6.5 0.0034 17.4 6.5 2.7 2 1 0 2 2 2 1 MSP1 EGF domain 1 Laminin_EGF PF00053.24 VBB32476.1 - 0.71 10.1 24.5 1.1 9.5 15.2 2.7 1 1 1 2 2 2 0 Laminin EGF domain Neur_chan_LBD PF02931.23 VBB32477.1 - 8.1e-41 139.8 0.3 1.1e-40 139.4 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB32477.1 - 8e-14 52.3 0.8 8e-14 52.3 0.8 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM_like_2 PF16357.5 VBB32477.1 - 0.098 12.6 0.2 0.098 12.6 0.2 2.0 2 0 0 2 2 2 0 Putative PepSY_TM-like Solute_trans_a PF03619.16 VBB32478.1 - 3.6e-20 72.6 16.9 4.6e-20 72.2 16.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha OAD_gamma PF04277.13 VBB32478.1 - 0.59 10.8 5.6 13 6.4 1.5 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HRG PF16954.5 VBB32478.1 - 8.1 6.9 11.3 29 5.2 7.2 3.5 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene BAR PF03114.18 VBB32479.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 5.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 VBB32479.1 - 0.00041 19.6 5.8 0.00052 19.3 5.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 VBB32479.1 - 0.023 14.4 8.0 0.008 15.9 3.9 1.8 1 1 1 2 2 2 0 BAR domain of APPL family DUF4419 PF14388.6 VBB32479.1 - 0.03 13.7 0.5 0.97 8.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4419) Com_YlbF PF06133.11 VBB32479.1 - 0.068 13.8 0.2 0.068 13.8 0.2 2.5 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Yos1 PF08571.10 VBB32479.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Yos1-like PAP2_C PF14360.6 VBB32480.1 - 8.6e-16 58.2 4.4 1.5e-15 57.5 4.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2 PF01569.21 VBB32480.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PAP2 superfamily PAP2_3 PF14378.6 VBB32480.1 - 0.086 12.5 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 PAP2 superfamily PRKCSH PF07915.13 VBB32481.1 - 3.9e-13 50.2 2.4 3.9e-13 50.2 2.4 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 VBB32481.1 - 0.00015 21.5 0.4 0.00041 20.1 0.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein EAP30 PF04157.16 VBB32481.1 - 0.1 11.9 4.3 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 EAP30/Vps36 family Ham1p_like PF01725.16 VBB32482.1 - 4.5e-48 163.7 0.0 6.7e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Ham1 family Bac_surface_Ag PF01103.23 VBB32483.1 - 1.2e-13 51.3 0.1 1.3e-13 51.2 0.1 1.0 1 0 0 1 1 1 1 Surface antigen Clc-like PF07062.12 VBB32485.1 - 1.7e-65 220.5 5.1 3.9e-40 137.6 0.1 2.0 1 1 1 2 2 2 2 Clc-like Claudin_3 PF06653.11 VBB32485.1 - 0.0002 21.3 1.3 0.013 15.5 0.1 2.2 2 0 0 2 2 2 2 Tight junction protein, Claudin-like fn3 PF00041.21 VBB32486.1 - 2.5e-22 79.0 0.0 2.3e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB32486.1 - 2.7e-05 24.6 0.6 5.8e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 VBB32486.1 - 0.12 12.7 0.1 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 VBB32486.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) PAX PF00292.18 VBB32487.1 - 2.6e-48 163.1 0.3 4.2e-48 162.4 0.3 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 VBB32487.1 - 1.6e-21 75.9 2.5 3.3e-21 74.9 2.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB32487.1 - 5.2e-06 26.3 0.7 1.5e-05 24.8 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 VBB32487.1 - 2.7e-05 23.8 0.1 0.00041 20.1 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 VBB32487.1 - 0.0019 18.8 2.2 0.091 13.4 0.0 3.1 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 VBB32487.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain MCLC PF05934.11 VBB32488.1 - 0.014 14.1 0.2 0.014 14.1 0.2 1.9 1 1 1 2 2 2 0 Mid-1-related chloride channel (MCLC) SK_channel PF03530.14 VBB32489.1 - 2.6e-33 114.4 3.0 2.7e-33 114.4 0.1 2.2 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 VBB32489.1 - 7.3e-24 83.8 4.1 7.4e-24 83.7 2.5 1.8 2 0 0 2 2 2 1 Calmodulin binding domain Ion_trans_2 PF07885.16 VBB32489.1 - 2.4e-12 46.6 6.6 2.4e-12 46.6 6.6 2.0 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 VBB32489.1 - 0.00011 22.1 1.0 0.00023 21.1 0.8 1.6 1 1 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.31 VBB32489.1 - 0.0022 17.2 2.7 0.005 16.1 2.7 1.7 1 0 0 1 1 1 1 Ion transport protein ELP6 PF09807.9 VBB32489.1 - 0.017 14.5 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Elongation complex protein 6 IRK PF01007.20 VBB32489.1 - 0.22 11.3 7.8 0.13 12.1 4.8 2.1 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain TSC22 PF01166.18 VBB32491.1 - 0.042 14.2 0.1 0.084 13.2 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family IKBKB_SDD PF18397.1 VBB32491.1 - 0.044 13.1 0.7 0.062 12.6 0.7 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain DUF3734 PF12536.8 VBB32491.1 - 0.12 12.7 1.7 0.18 12.1 1.7 1.2 1 0 0 1 1 1 0 Patatin phospholipase MARVEL PF01284.23 VBB32492.1 - 0.0017 18.4 9.1 0.0024 17.9 9.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_3_6 PF07332.11 VBB32492.1 - 0.92 9.6 5.4 0.4 10.7 0.6 2.1 1 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ERM PF00769.19 VBB32493.1 - 0.0023 17.8 39.6 0.09 12.6 12.1 2.7 1 1 2 3 3 3 3 Ezrin/radixin/moesin family ATG16 PF08614.11 VBB32493.1 - 1 9.5 29.4 0.018 15.3 13.0 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) B56 PF01603.20 VBB32494.1 - 1.1e-174 581.3 8.2 1.5e-174 580.8 8.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Takusan PF04822.13 VBB32494.1 - 0.012 15.4 0.2 3.5 7.6 0.0 3.3 3 0 0 3 3 3 0 Takusan Sec7_N PF12783.7 VBB32494.1 - 0.038 13.9 4.0 0.29 11.0 0.2 3.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RIH_assoc PF08454.11 VBB32494.1 - 0.062 13.2 1.0 0.74 9.7 0.0 2.7 3 0 0 3 3 3 0 RyR and IP3R Homology associated OLF PF02191.16 VBB32495.1 - 2.2e-21 76.6 1.5 3.7e-21 75.8 1.5 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 VBB32495.1 - 3.1e-08 33.3 9.2 4.8e-08 32.6 9.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Biopterin_H PF00351.21 VBB32496.1 - 1.5e-131 438.3 0.2 1.8e-131 438.2 0.2 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase SANT_DAMP1_like PF16282.5 VBB32496.1 - 0.002 18.3 0.1 0.0069 16.5 0.1 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Syntaxin-6_N PF09177.11 VBB32496.1 - 0.051 14.1 0.0 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HTH_51 PF18558.1 VBB32496.1 - 0.12 12.2 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Carb_anhydrase PF00194.21 VBB32497.1 - 4.8e-60 203.2 0.0 6e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.21 VBB32498.1 - 2.3e-11 43.9 0.4 0.023 15.0 0.0 3.4 3 0 0 3 3 3 3 Fibronectin type III domain Sulfate_transp PF00916.20 VBB32499.1 - 1.7e-94 316.7 16.1 1.7e-94 316.7 16.1 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 VBB32499.1 - 5.9e-21 74.3 0.1 1e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain Chordopox_L2 PF05803.12 VBB32499.1 - 0.11 12.4 1.9 0.33 10.8 0.0 2.7 2 0 0 2 2 2 0 Chordopoxvirus L2 protein STAS_2 PF13466.6 VBB32499.1 - 0.22 11.9 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain Phe_ZIP PF08916.11 VBB32501.1 - 6e-05 23.7 0.6 0.00026 21.6 0.1 2.1 2 0 0 2 2 2 1 Phenylalanine zipper Cation_efflux PF01545.21 VBB32502.1 - 2.1e-51 174.5 9.4 2.6e-51 174.2 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3989 PF13150.6 VBB32502.1 - 0.086 12.6 0.5 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) ZT_dimer PF16916.5 VBB32502.1 - 0.11 12.7 2.4 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter DUF4668 PF15701.5 VBB32502.1 - 1.4 8.8 5.2 9.8 6.0 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) Glyco_hydro_99 PF16317.5 VBB32503.1 - 1.3e-106 356.6 10.7 1.6e-54 185.3 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 VBB32503.1 - 0.00025 20.6 0.0 0.00065 19.3 0.0 1.7 3 0 0 3 3 3 1 Glycosyltransferase WbsX DUF4446 PF14584.6 VBB32503.1 - 0.057 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CRA PF06589.11 VBB32503.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF3070 PF11270.8 VBB32503.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) PDZ PF00595.24 VBB32504.1 - 1e-22 80.3 0.3 1.9e-13 50.5 0.0 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 VBB32504.1 - 8e-12 44.8 1.1 0.00011 21.9 0.1 3.2 3 0 0 3 3 3 2 PDZ domain Ser_hydrolase PF06821.13 VBB32504.1 - 0.018 14.9 0.1 0.099 12.5 0.1 2.1 3 0 0 3 3 3 0 Serine hydrolase DUF2441 PF10386.9 VBB32505.1 - 0.065 13.2 0.1 0.065 13.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) DUF5387 PF17361.2 VBB32505.1 - 1.1 8.9 20.9 0.15 11.7 14.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5387) GATA PF00320.27 VBB32506.1 - 8.4e-14 50.9 3.7 8.4e-14 50.9 3.7 2.7 3 0 0 3 3 3 1 GATA zinc finger zf-RRN7 PF11781.8 VBB32506.1 - 0.0046 16.6 1.9 0.0046 16.6 1.9 3.0 4 0 0 4 4 4 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Vps36-NZF-N PF16988.5 VBB32506.1 - 0.017 14.5 7.0 0.077 12.4 0.1 3.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Baseplate_J PF04865.14 VBB32506.1 - 0.025 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Baseplate J-like protein OrfB_Zn_ribbon PF07282.11 VBB32506.1 - 0.053 13.4 9.7 0.15 12.0 1.9 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 VBB32506.1 - 4.7 7.4 5.4 18 5.5 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Zona_pellucida PF00100.23 VBB32507.1 - 7.9e-13 48.8 3.8 9.7e-13 48.5 3.8 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 VBB32508.1 - 1.5e-09 38.0 0.4 1.8e-09 37.8 0.4 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SNF PF00209.18 VBB32509.1 - 4.6e-168 560.1 28.8 7.2e-167 556.2 28.8 1.9 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family PgaD PF13994.6 VBB32509.1 - 2.2 8.3 6.9 6.2 6.9 6.1 2.2 2 0 0 2 2 2 0 PgaD-like protein PCAF_N PF06466.11 VBB32510.1 - 6.2e-41 140.6 0.8 1e-40 139.9 0.8 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 VBB32510.1 - 6.8e-18 64.5 0.1 2.2e-17 62.9 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 VBB32510.1 - 7e-08 32.7 0.3 2.4e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 VBB32510.1 - 3.8e-05 24.0 0.9 9.3e-05 22.8 0.9 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 VBB32510.1 - 4.6e-05 23.4 0.2 9.6e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Redoxin PF08534.10 VBB32510.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin SNF2_N PF00176.23 VBB32511.1 - 6e-48 163.3 0.0 1.1e-47 162.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 VBB32511.1 - 1.9e-17 63.6 0.4 1e-16 61.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 VBB32511.1 - 6.1e-09 36.1 0.0 4.7e-08 33.2 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 VBB32511.1 - 0.11 12.1 0.1 1.1 8.9 0.0 2.6 2 1 0 2 2 2 0 SWI2/SNF2 ATPase RRM_1 PF00076.22 VBB32513.1 - 0.073 12.9 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RINGv PF12906.7 VBB32514.1 - 6.5e-16 58.2 10.7 1.2e-15 57.3 10.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 VBB32514.1 - 0.0036 17.6 10.2 0.0098 16.2 10.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 VBB32514.1 - 0.02 14.6 5.4 0.057 13.2 5.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 VBB32514.1 - 0.025 14.6 3.1 0.041 13.8 3.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF587 PF04532.12 VBB32514.1 - 0.059 12.6 0.5 0.087 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) FANCL_C PF11793.8 VBB32514.1 - 0.19 11.9 8.0 0.16 12.2 5.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain RRM_1 PF00076.22 VBB32515.1 - 1.1e-10 41.2 0.2 1.1e-07 31.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 VBB32515.1 - 0.0024 17.9 0.2 0.031 14.3 0.1 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Claudin_2 PF13903.6 VBB32516.1 - 4.8e-10 39.5 0.0 6.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 VBB32516.1 - 0.017 15.0 0.4 0.038 13.8 0.3 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Tetraspanin PF00335.20 VBB32516.1 - 0.21 11.3 2.7 0.34 10.6 1.7 1.8 2 0 0 2 2 2 0 Tetraspanin family Neur_chan_LBD PF02931.23 VBB32517.1 - 1.6e-45 155.2 2.3 1.3e-43 149.0 2.3 2.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Lectin_C PF00059.21 VBB32517.1 - 6.8e-07 30.0 4.6 2.5e-06 28.2 4.6 2.0 1 0 0 1 1 1 1 Lectin C-type domain Ac110_PIF PF07280.11 VBB32517.1 - 0.36 10.7 4.6 0.92 9.3 0.7 2.4 2 0 0 2 2 2 0 Per os infectivity factor AC110 Adeno_E3 PF06040.11 VBB32518.1 - 1.4 9.1 4.9 0.24 11.6 0.5 1.9 2 1 0 2 2 2 0 Adenovirus E3 protein Arg_decarbox_C PF17944.1 VBB32518.1 - 3.4 8.3 0.0 3.4 8.3 0.0 3.2 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension FANC_SAP PF18081.1 VBB32518.1 - 3.4 7.9 11.0 0.64 10.2 5.7 2.6 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain TFIIA PF03153.13 VBB32518.1 - 5.5 6.9 35.9 6.9 6.6 35.8 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BLOC1S3 PF15753.5 VBB32519.1 - 1.2e-08 35.2 5.1 3.8e-08 33.7 5.1 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 TPR_2 PF07719.17 VBB32520.1 - 9.1e-21 72.2 9.6 4.4e-05 23.3 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 VBB32520.1 - 4.4e-13 48.3 10.0 0.01 16.0 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 VBB32520.1 - 4.8e-13 48.3 18.6 0.00077 19.2 0.1 5.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 VBB32520.1 - 7.4e-13 47.9 13.8 9.1e-07 28.5 0.1 5.1 4 1 1 5 5 5 4 TPR repeat TPR_14 PF13428.6 VBB32520.1 - 4.7e-10 39.4 0.9 0.069 14.0 0.0 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB32520.1 - 1.2e-08 35.1 10.7 0.059 13.7 0.2 4.1 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB32520.1 - 6e-08 33.2 7.8 0.012 16.2 0.7 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB32520.1 - 7.3e-08 31.9 6.9 0.24 11.5 0.2 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB32520.1 - 3.7e-07 30.1 2.3 0.024 15.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB32520.1 - 4.1e-05 23.3 9.0 0.17 11.8 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB32520.1 - 0.00013 22.1 0.2 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32520.1 - 0.00015 22.2 6.5 1.5 9.4 1.6 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB32520.1 - 0.00022 21.2 1.3 0.0096 16.0 0.1 3.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 VBB32520.1 - 0.0071 16.4 5.1 1.4 9.1 0.1 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 VBB32520.1 - 0.012 16.2 8.8 0.95 10.2 0.0 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat SPO22 PF08631.10 VBB32520.1 - 0.027 13.9 0.3 0.071 12.6 0.1 1.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF5113 PF17140.4 VBB32520.1 - 0.028 14.2 3.4 1.2 8.9 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5113) TPR_3 PF07720.12 VBB32520.1 - 0.099 12.7 14.0 0.15 12.1 4.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP13 PF12921.7 VBB32520.1 - 0.14 12.0 0.6 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase expression SHNi-TPR PF10516.9 VBB32520.1 - 0.97 8.9 3.3 38 3.8 0.3 3.2 3 0 0 3 3 3 0 SHNi-TPR ANAPC3 PF12895.7 VBB32520.1 - 3.8 7.8 6.8 5.2 7.4 0.9 3.1 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MCRS_N PF13325.6 VBB32524.1 - 3.5e-44 151.2 1.6 3.5e-44 151.2 1.6 1.5 2 0 0 2 2 2 1 N-terminal region of micro-spherule protein FHA PF00498.26 VBB32524.1 - 0.0006 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 VBB32524.1 - 0.092 13.0 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 FHA domain RGS PF00615.19 VBB32525.1 - 7.3e-33 113.3 0.1 1.6e-32 112.3 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain G-gamma PF00631.22 VBB32525.1 - 3.6e-11 42.9 0.1 9.2e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 GGL domain dCache_1 PF02743.18 VBB32526.1 - 1.9e-07 31.1 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 2 Cache domain LRV_FeS PF05484.11 VBB32526.1 - 0.0015 18.5 0.8 0.19 11.8 0.0 2.8 2 0 0 2 2 2 2 LRV protein FeS4 cluster TRP_2 PF08344.11 VBB32527.1 - 1.3e-10 41.3 1.4 2.3e-10 40.5 1.4 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II DUF2650 PF10853.8 VBB32529.1 - 3.9e-05 23.3 1.2 8e-05 22.3 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) RNase_P_p30 PF01876.16 VBB32530.1 - 4.5e-36 124.3 0.0 9.8e-36 123.2 0.0 1.6 1 1 0 1 1 1 1 RNase P subunit p30 CS PF04969.16 VBB32530.1 - 6e-11 43.2 0.2 2.7e-10 41.1 0.1 2.3 2 0 0 2 2 2 1 CS domain tRNA_m1G_MT PF01746.21 VBB32531.1 - 2.1e-22 79.8 0.0 3.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase zf-AN1 PF01428.16 VBB32532.1 - 5.6e-06 26.4 6.0 1.2e-05 25.3 6.0 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 VBB32532.1 - 6.7e-05 22.6 0.4 0.0002 21.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family FYVE PF01363.21 VBB32532.1 - 0.043 13.9 3.5 0.12 12.5 3.5 1.8 1 0 0 1 1 1 0 FYVE zinc finger PP2C PF00481.21 VBB32534.1 - 7.4e-17 61.8 0.0 1.9e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C4 PF00105.18 VBB32535.1 - 1.7e-29 102.1 13.1 1.7e-29 102.1 13.1 2.7 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB32535.1 - 1.1e-21 77.4 0.9 1.1e-21 77.4 0.9 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Adeno_GP19K PF04881.13 VBB32535.1 - 0.1 12.6 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Adenovirus GP19K Sin_N PF04801.13 VBB32536.1 - 2.6e-91 307.0 0.0 3e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region DUF5452 PF17533.2 VBB32536.1 - 0.018 15.2 2.1 0.04 14.0 2.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5452) SIS PF01380.22 VBB32537.1 - 1.3e-54 183.6 0.0 4.4e-33 113.9 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 VBB32537.1 - 7.2e-20 71.6 0.0 1.6e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 VBB32537.1 - 7.8e-15 54.9 0.2 3.4e-14 52.8 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_4 PF13230.6 VBB32537.1 - 1.2e-06 27.6 0.1 2.4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 VBB32537.1 - 0.00059 19.9 0.0 0.0099 15.9 0.0 2.6 2 1 1 3 3 3 1 SIS domain GATase_2 PF00310.21 VBB32537.1 - 0.094 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II RhoGEF PF00621.20 VBB32538.1 - 6.9e-13 49.2 0.2 1.5e-12 48.1 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 VBB32538.1 - 5.3e-12 46.2 0.1 2.3e-08 34.5 0.3 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 VBB32538.1 - 0.43 11.0 2.0 3 8.3 0.5 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain PIG-X PF08320.12 VBB32539.1 - 1.8e-16 60.7 0.1 2.1e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.25 VBB32540.1 - 2.4e-68 230.3 0.0 2.9e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32540.1 - 8.7e-47 159.6 0.0 1.1e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32540.1 - 1.9e-07 30.7 0.0 6.5e-07 29.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 VBB32540.1 - 2.6e-07 29.8 0.0 7.9e-07 28.2 0.0 1.5 1 1 1 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 VBB32540.1 - 4.7e-06 25.8 0.1 9.6e-06 24.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 VBB32540.1 - 0.0019 17.6 0.2 0.0031 16.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 VBB32540.1 - 0.018 14.7 0.6 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 APH PF01636.23 VBB32540.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 VBB32540.1 - 0.08 12.6 1.5 0.5 10.0 0.4 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Roc PF08477.13 VBB32541.1 - 4.7e-14 52.6 0.2 6.2e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB32541.1 - 1.1e-13 51.1 0.1 1.4e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Ras family AAA_7 PF12775.7 VBB32541.1 - 0.00057 19.5 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 VBB32541.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 VBB32541.1 - 0.002 18.4 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 VBB32541.1 - 0.0031 17.0 0.0 0.0038 16.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 VBB32541.1 - 0.004 16.6 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 VBB32541.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 VBB32541.1 - 0.021 13.9 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 VBB32541.1 - 0.026 13.7 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 VBB32541.1 - 0.034 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 VBB32541.1 - 0.035 13.8 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 VBB32541.1 - 0.041 13.6 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 VBB32541.1 - 0.051 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB32541.1 - 0.098 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 VBB32541.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 VBB32541.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ras PF00071.22 VBB32542.1 - 3.2e-15 56.1 0.0 4.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 VBB32542.1 - 0.0021 17.5 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB32542.1 - 0.0042 17.3 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 VBB32542.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain eRF1_2 PF03464.15 VBB32542.1 - 0.026 14.8 0.0 0.047 14.0 0.0 1.4 1 1 0 1 1 1 0 eRF1 domain 2 GTP_EFTU PF00009.27 VBB32542.1 - 0.042 13.4 0.0 0.057 12.9 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MelC1 PF06236.11 VBB32544.1 - 0.083 13.0 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 PET PF06297.14 VBB32545.1 - 1.8e-29 101.9 0.1 3.6e-29 100.9 0.0 1.5 2 0 0 2 2 2 1 PET Domain LIM PF00412.22 VBB32545.1 - 2.1e-10 40.6 5.6 2.1e-10 40.6 5.6 2.7 3 1 0 3 3 3 1 LIM domain RNA_pol_A_bac PF01000.26 VBB32548.1 - 8.2e-37 126.0 0.1 1.4e-36 125.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 VBB32548.1 - 1.1e-19 69.6 0.0 1.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain E7 PF00527.18 VBB32548.1 - 0.034 14.3 0.4 0.21 11.8 0.3 2.2 2 0 0 2 2 2 0 E7 protein, Early protein Actin PF00022.19 VBB32549.1 - 1.1e-91 307.5 0.0 3.7e-90 302.5 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 VBB32549.1 - 0.0001 21.2 0.0 0.32 9.8 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 VBB32549.1 - 0.006 17.0 0.0 0.028 14.8 0.0 2.2 2 1 0 2 2 2 1 Cell division protein FtsA Hexapep PF00132.24 VBB32550.1 - 4.5e-09 35.7 21.9 2.1e-06 27.2 10.3 4.9 4 1 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 VBB32550.1 - 7.2e-05 22.4 5.3 7.2e-05 22.4 5.3 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Piwi PF02171.17 VBB32552.1 - 5.8e-21 75.0 0.1 9.2e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 VBB32552.1 - 2.5e-14 53.3 0.5 1.8e-13 50.5 0.2 2.2 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 VBB32552.1 - 0.00088 19.5 0.1 0.003 17.8 0.1 2.0 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 VBB32552.1 - 0.0014 19.2 0.0 0.0034 18.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute EF-hand_14 PF17959.1 VBB32552.1 - 0.12 12.7 0.3 0.62 10.5 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain CLASP_N PF12348.8 VBB32555.1 - 6.5e-14 52.0 8.3 8e-07 28.8 0.2 3.3 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 VBB32555.1 - 1e-08 34.7 4.3 0.12 12.7 0.0 5.4 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 VBB32555.1 - 2e-07 31.3 4.4 0.053 13.9 0.1 4.7 4 0 0 4 4 4 3 HEAT repeats Cnd1 PF12717.7 VBB32555.1 - 8.1e-06 26.0 16.3 0.023 14.7 0.2 5.4 3 3 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 VBB32555.1 - 4.2e-05 24.1 3.7 1.1 9.9 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 VBB32555.1 - 0.0012 18.5 1.0 0.39 10.3 0.0 3.9 3 1 0 3 3 3 1 NUC173 domain NopRA1 PF16201.5 VBB32555.1 - 0.012 15.2 1.7 0.69 9.5 0.3 3.1 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 ArsA_ATPase PF02374.15 VBB32555.1 - 0.013 14.7 0.3 0.063 12.5 0.0 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase RTP1_C1 PF10363.9 VBB32555.1 - 0.016 15.4 0.1 0.23 11.7 0.0 3.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 VBB32555.1 - 0.018 15.5 1.2 29 5.3 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat CNOT11 PF10155.9 VBB32555.1 - 0.19 11.9 2.3 2.9 8.1 0.3 3.1 1 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Baculo_p24 PF05073.12 VBB32555.1 - 0.67 9.7 3.1 1.1 9.0 0.7 2.5 1 1 1 2 2 2 0 Baculovirus P24 capsid protein ANAPC4_WD40 PF12894.7 VBB32556.1 - 1.4e-10 41.3 2.6 0.0002 21.6 0.1 5.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 VBB32556.1 - 0.0001 21.5 1.4 0.00045 19.4 0.6 2.5 3 0 0 3 3 3 1 Coatomer WD associated region Ge1_WD40 PF16529.5 VBB32556.1 - 0.0018 17.3 0.1 0.68 8.8 0.0 3.4 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 VBB32556.1 - 0.0035 17.2 0.0 0.81 9.7 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 VBB32556.1 - 0.0087 16.9 2.3 23 6.1 0.1 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat CDC37_C PF08564.10 VBB32556.1 - 0.13 12.4 0.3 0.31 11.2 0.3 1.6 1 0 0 1 1 1 0 Cdc37 C terminal domain AAA_19 PF13245.6 VBB32556.1 - 0.16 12.3 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain TFIIF_alpha PF05793.12 VBB32557.1 - 4.1e-99 332.6 43.5 1.5e-78 264.7 32.0 2.4 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP_sp32 PF07222.12 VBB32557.1 - 3.7 6.9 12.8 2.7 7.4 0.8 2.4 2 0 0 2 2 2 0 Proacrosin binding protein sp32 SCO1-SenC PF02630.14 VBB32558.1 - 2.5e-47 160.2 0.0 4e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 VBB32558.1 - 0.0014 18.9 1.2 0.0038 17.5 0.0 2.3 2 2 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 VBB32558.1 - 0.0072 16.2 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Ras PF00071.22 VBB32560.1 - 5.7e-55 185.3 0.0 7.3e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB32560.1 - 2.9e-18 66.2 0.0 7.9e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB32560.1 - 1.3e-10 41.1 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB32560.1 - 8.5e-06 25.4 0.0 3.1e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 VBB32560.1 - 0.0001 22.3 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 VBB32560.1 - 0.00016 21.6 1.7 0.0012 18.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 VBB32560.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 VBB32560.1 - 0.014 14.6 3.0 1.1 8.3 0.2 2.4 1 1 2 3 3 3 0 G-protein alpha subunit FeoB_N PF02421.18 VBB32560.1 - 0.018 14.6 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 VBB32560.1 - 0.084 13.2 0.2 0.19 12.1 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain SUIM_assoc PF16619.5 VBB32560.1 - 2.1 8.5 14.8 2.2 8.4 11.0 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA PF00004.29 VBB32561.1 - 9.9e-46 155.4 0.0 4.8e-37 127.3 0.1 3.0 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB32561.1 - 1.9e-09 37.2 0.3 2.5e-06 27.2 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 VBB32561.1 - 1.5e-06 28.7 0.1 0.15 12.4 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 VBB32561.1 - 7.4e-06 26.0 0.0 0.059 13.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 VBB32561.1 - 2.4e-05 23.8 0.5 0.019 14.4 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 VBB32561.1 - 3.3e-05 24.4 0.0 0.24 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 VBB32561.1 - 0.00033 20.6 0.1 2 8.3 0.0 3.4 3 1 0 3 3 2 2 NACHT domain AAA_22 PF13401.6 VBB32561.1 - 0.00054 20.2 0.1 0.072 13.4 0.1 3.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 VBB32561.1 - 0.00086 19.7 0.0 0.083 13.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 VBB32561.1 - 0.0021 18.0 0.1 0.83 9.6 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 VBB32561.1 - 0.0022 17.8 0.1 0.13 12.0 0.0 3.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 VBB32561.1 - 0.0028 17.2 0.0 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 VBB32561.1 - 0.0039 16.4 0.0 0.88 8.7 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 VBB32561.1 - 0.0044 17.1 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 VBB32561.1 - 0.0081 15.9 0.0 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 VBB32561.1 - 0.026 14.9 0.1 8.5 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 VBB32561.1 - 0.03 13.5 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_2 PF07724.14 VBB32561.1 - 0.033 14.3 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 VBB32561.1 - 0.036 14.1 0.1 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 VBB32561.1 - 0.042 14.0 0.0 8.4 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 VBB32561.1 - 0.046 13.1 0.2 4.9 6.4 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 VBB32561.1 - 0.048 13.4 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 VBB32561.1 - 0.05 13.3 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 VBB32561.1 - 0.071 12.2 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 VBB32561.1 - 0.077 12.2 0.1 0.51 9.5 0.1 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 VBB32561.1 - 0.079 12.7 0.0 16 5.2 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 VBB32561.1 - 0.16 11.7 0.0 21 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 VBB32561.1 - 3.4 7.2 5.1 2.4 7.7 0.1 2.8 3 0 0 3 3 3 0 AAA domain Collagen PF01391.18 VBB32562.1 - 7e-24 83.4 74.0 1.8e-10 40.4 20.5 3.4 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32562.1 - 3.2e-18 65.5 0.6 4.4e-18 65.1 0.6 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain zf-rbx1 PF12678.7 VBB32563.1 - 1.6e-07 31.5 4.9 3e-07 30.6 4.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 VBB32563.1 - 5.1e-07 29.9 6.9 5.1e-07 29.9 6.9 1.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 VBB32563.1 - 3.6e-06 26.8 6.8 6.1e-06 26.1 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 VBB32563.1 - 9.6e-06 25.3 7.8 2e-05 24.4 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB32563.1 - 2.1e-05 24.3 5.9 4e-05 23.4 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB32563.1 - 2.8e-05 23.9 5.6 7.2e-05 22.6 5.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 VBB32563.1 - 0.00086 19.0 3.9 0.0026 17.4 3.9 1.9 1 1 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 VBB32563.1 - 0.004 17.2 1.4 0.009 16.0 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 VBB32563.1 - 0.012 15.6 5.1 0.04 13.9 5.0 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 VBB32563.1 - 0.014 15.5 3.9 0.038 14.2 3.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 VBB32563.1 - 0.018 14.9 6.5 0.018 14.9 6.5 1.6 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 DUF2118 PF09891.9 VBB32563.1 - 0.018 15.0 0.2 0.024 14.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Rad50_zn_hook PF04423.14 VBB32563.1 - 0.024 14.5 2.3 4.4 7.2 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 VBB32563.1 - 0.049 13.8 3.6 0.084 13.0 3.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Rtf2 PF04641.12 VBB32563.1 - 0.06 12.7 2.6 0.15 11.4 2.6 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger DZR PF12773.7 VBB32563.1 - 0.092 12.8 2.9 6 7.0 0.5 2.2 1 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 VBB32563.1 - 0.092 12.6 6.9 0.53 10.2 6.9 2.2 1 1 2 3 3 3 0 PHD-finger Prok-RING_1 PF14446.6 VBB32563.1 - 0.46 10.4 7.9 4.7 7.2 0.4 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-TFIIIC PF12660.7 VBB32563.1 - 0.57 10.2 3.9 1.3 9.1 3.9 1.7 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Zf_RING PF16744.5 VBB32563.1 - 0.77 9.9 4.4 29 4.8 4.7 2.9 1 1 1 2 2 2 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 VBB32563.1 - 0.86 9.3 10.8 0.066 12.8 4.9 2.1 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type EF-hand_7 PF13499.6 VBB32564.1 - 9.1e-15 54.9 7.7 2.1e-12 47.3 3.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB32564.1 - 1.9e-11 42.7 4.7 9.5e-05 21.7 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 VBB32564.1 - 9.3e-09 34.5 5.5 0.00063 19.5 0.5 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 VBB32564.1 - 0.00055 19.7 8.0 0.0019 18.0 1.3 2.9 2 1 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB32564.1 - 0.0016 18.7 0.3 0.003 17.8 0.3 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 VBB32564.1 - 0.044 13.3 0.8 1.3 8.6 0.0 2.9 2 0 0 2 2 2 0 EF hand DUF3349 PF11829.8 VBB32564.1 - 0.054 14.3 0.1 0.092 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) PMBR PF09373.10 VBB32564.1 - 0.11 12.7 0.1 5.2 7.4 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat Band_7 PF01145.25 VBB32565.1 - 3.6e-28 98.8 1.0 3.6e-28 98.8 1.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 VBB32565.1 - 6.4e-24 83.8 0.5 6.4e-24 83.8 0.5 2.5 4 0 0 4 4 4 1 C-terminal region of band_7 Band_7_1 PF13421.6 VBB32565.1 - 0.028 14.1 0.2 0.058 13.1 0.2 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family NSP2_assoc PF14758.6 VBB32565.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein SH2 PF00017.24 VBB32566.1 - 6.1e-15 55.1 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain PID PF00640.23 VBB32566.1 - 1.1e-12 48.1 0.1 1.7e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) FAD-oxidase_C PF02913.19 VBB32567.1 - 4.6e-52 177.1 0.0 5.5e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 VBB32567.1 - 7.5e-12 45.2 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Carb_kinase PF01256.17 VBB32568.1 - 9e-58 195.6 0.0 1e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 VBB32568.1 - 4.3e-06 26.3 0.0 6.5e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 VBB32568.1 - 0.081 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase BAR PF03114.18 VBB32569.1 - 6.9e-19 68.4 2.6 8.6e-19 68.1 2.6 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 VBB32569.1 - 0.00041 19.6 3.1 0.00041 19.6 3.1 1.7 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Imm59 PF15597.6 VBB32569.1 - 0.029 14.8 0.2 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 59 DUF16 PF01519.16 VBB32569.1 - 1.4 9.4 5.6 5.1 7.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DnaJ PF00226.31 VBB32570.1 - 0.0007 19.7 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 2 DnaJ domain Fic PF02661.18 VBB32571.1 - 3.9e-25 88.6 0.0 1.3e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family TPR_19 PF14559.6 VBB32571.1 - 0.00018 22.0 0.5 0.039 14.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB32571.1 - 0.0029 17.6 0.3 0.57 10.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB32571.1 - 0.0041 17.8 1.6 3.5 8.7 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB32571.1 - 0.0043 17.7 1.1 0.07 13.8 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB32571.1 - 0.017 14.9 0.1 0.25 11.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 VBB32571.1 - 0.026 14.6 0.3 1.8 8.8 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB32571.1 - 0.098 13.1 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Alpha-amylase PF00128.24 VBB32572.1 - 1.2e-39 136.8 0.6 1.7e-39 136.3 0.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 VBB32572.1 - 2e-22 78.6 2.3 3.4e-22 77.8 2.3 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus RRM_1 PF00076.22 VBB32573.1 - 7.6e-17 60.9 0.0 1.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.6 VBB32574.1 - 1.7e-22 79.7 6.7 2.3e-14 53.6 0.7 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 VBB32574.1 - 2.3e-21 73.7 9.5 1e-06 27.8 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 VBB32574.1 - 8.4e-21 72.1 4.7 3.9e-05 23.2 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 VBB32574.1 - 2.2e-16 58.5 4.1 9.1e-05 21.8 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 VBB32574.1 - 5.3e-16 58.2 4.5 7.3e-08 32.1 0.1 3.5 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB32574.1 - 2.3e-06 27.9 2.6 0.11 12.9 0.2 3.3 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 VBB32574.1 - 0.00063 19.7 5.9 2.4 8.1 0.6 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 VBB32574.1 - 0.0014 18.9 1.8 1.2 9.5 0.3 3.6 2 1 1 3 3 3 1 EF-hand domain EF-hand_13 PF17958.1 VBB32574.1 - 0.0047 16.7 0.1 5.7 6.8 0.1 3.1 3 1 0 3 3 3 2 EF-hand domain OST-HTH PF12872.7 VBB32574.1 - 0.016 15.1 0.3 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Caleosin PF05042.13 VBB32574.1 - 0.098 12.6 3.8 13 5.6 0.0 3.6 2 1 2 4 4 4 0 Caleosin related protein MORN_2 PF07661.13 VBB32574.1 - 0.19 12.1 2.7 38 5.0 0.0 3.7 3 1 1 4 4 4 0 MORN repeat variant Dockerin_1 PF00404.18 VBB32574.1 - 0.9 9.8 3.2 9.1 6.6 0.2 2.8 2 1 0 2 2 2 0 Dockerin type I domain Glyco_transf_21 PF13506.6 VBB32575.1 - 1.7e-39 135.0 0.0 3.1e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 VBB32575.1 - 5.3e-10 39.6 0.0 8.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 VBB32575.1 - 4.2e-05 23.5 3.1 7.9e-05 22.6 3.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Vps35 PF03635.17 VBB32576.1 - 2.8e-266 885.7 13.1 3.1e-266 885.5 13.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF758 PF05527.11 VBB32576.1 - 0.096 12.7 0.2 0.29 11.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF758) zf-H2C2_2 PF13465.6 VBB32577.1 - 1.1e-10 41.4 10.3 8e-07 29.2 3.5 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB32577.1 - 8.4e-10 38.6 27.5 0.0018 18.7 5.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB32577.1 - 3e-06 27.6 26.2 0.0088 16.8 5.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 VBB32577.1 - 0.0032 18.0 6.2 0.67 10.6 1.5 2.9 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 VBB32577.1 - 0.16 12.3 9.5 0.36 11.1 7.2 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 VBB32577.1 - 0.83 10.0 7.4 12 6.3 0.8 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB32577.1 - 1.1 9.7 11.6 5.9 7.4 3.7 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TP1 PF02079.16 VBB32577.1 - 8 6.4 8.8 2.2 8.2 5.5 1.9 2 0 0 2 2 2 0 Nuclear transition protein 1 HABP4_PAI-RBP1 PF04774.15 VBB32578.1 - 6.2e-21 75.4 6.9 6.2e-21 75.4 6.9 2.6 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 VBB32578.1 - 5.8e-06 27.0 9.1 5.8e-06 27.0 9.1 2.7 2 1 1 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal Stm1_N PF09598.10 VBB32578.1 - 3.3 8.6 11.1 3.6 8.5 7.3 3.1 2 1 0 2 2 2 0 Stm1 PX PF00787.24 VBB32579.1 - 2.5e-26 91.8 0.1 3.1e-26 91.6 0.1 1.1 1 0 0 1 1 1 1 PX domain Vps51 PF08700.11 VBB32580.1 - 8.2e-21 73.9 5.0 8.2e-21 73.9 5.0 2.5 3 0 0 3 3 3 1 Vps51/Vps67 Dor1 PF04124.12 VBB32580.1 - 1e-07 31.0 5.1 1e-07 31.0 5.1 2.3 3 0 0 3 3 3 1 Dor1-like family Sec5 PF15469.6 VBB32580.1 - 4.7e-06 26.5 11.5 7.6e-05 22.6 9.2 3.0 2 1 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.11 VBB32580.1 - 0.00041 20.4 7.3 0.00041 20.4 7.3 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 VBB32580.1 - 0.0029 17.8 4.6 0.0029 17.8 4.6 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Occludin_ELL PF07303.13 VBB32580.1 - 0.018 15.8 1.7 0.064 14.0 1.7 2.0 1 0 0 1 1 1 0 Occludin homology domain DUF4472 PF14739.6 VBB32580.1 - 0.025 15.3 1.3 0.092 13.5 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) SKA2 PF16740.5 VBB32580.1 - 0.043 13.6 6.6 0.34 10.7 3.5 3.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 MbeB_N PF04837.12 VBB32580.1 - 0.29 11.5 3.1 0.93 9.9 0.9 2.8 2 1 1 3 3 3 0 MbeB-like, N-term conserved region TMF_TATA_bd PF12325.8 VBB32580.1 - 0.46 10.7 8.0 0.25 11.6 4.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 VBB32580.1 - 0.54 10.3 8.1 0.044 13.8 1.4 2.8 4 0 0 4 4 4 0 Laminin Domain II MCPsignal PF00015.21 VBB32580.1 - 1.2 8.9 4.3 0.44 10.3 0.4 2.3 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Snapin_Pallidin PF14712.6 VBB32580.1 - 2.1 8.8 6.7 1.8 9.1 3.0 2.9 2 1 0 2 2 2 0 Snapin/Pallidin GAT PF03127.14 VBB32580.1 - 2.6 8.4 7.6 2.6 8.4 0.1 4.3 4 1 1 5 5 5 0 GAT domain BRE1 PF08647.11 VBB32580.1 - 6.9 6.8 11.1 5.1 7.2 8.0 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ShK PF01549.24 VBB32581.1 - 1.8e-07 31.6 4.9 2.6e-07 31.1 4.9 1.3 1 0 0 1 1 1 1 ShK domain-like CBFD_NFYB_HMF PF00808.23 VBB32582.1 - 2.8e-22 78.7 0.3 8.3e-22 77.3 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB32582.1 - 0.0003 21.1 0.1 0.0018 18.6 0.0 2.0 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF5598 PF18127.1 VBB32583.1 - 5.6e-35 119.7 0.4 1.3e-34 118.5 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5598) Flavokinase PF01687.17 VBB32583.1 - 7.9e-26 90.5 0.0 1.4e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Carn_acyltransf PF00755.20 VBB32584.1 - 5.6e-104 348.9 0.1 6.4e-104 348.7 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 VBB32584.1 - 1.6e-20 72.8 0.1 3e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus R3H-assoc PF13902.6 VBB32585.1 - 4.1e-29 101.7 0.4 8.2e-29 100.7 0.4 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 VBB32585.1 - 0.045 13.8 1.4 0.32 11.0 0.0 2.6 2 1 0 2 2 2 0 R3H domain 2-oxoacid_dh PF00198.23 VBB32586.1 - 2.5e-77 259.5 0.0 3.3e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 VBB32586.1 - 1e-21 76.5 0.5 2.3e-21 75.4 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 VBB32586.1 - 0.0021 17.8 0.0 0.011 15.5 0.0 2.2 2 1 0 2 2 2 1 Biotin-lipoyl like EAL PF00563.20 VBB32586.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 EAL domain QRPTase_N PF02749.16 VBB32586.1 - 0.03 14.3 0.1 0.095 12.8 0.1 1.9 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain AMP-binding PF00501.28 VBB32587.1 - 1.2e-27 96.6 0.0 1.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB32587.1 - 4.5e-12 46.8 1.1 1.1e-11 45.6 1.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CX PF01705.19 VBB32587.1 - 5.8e-06 26.7 2.3 1.4e-05 25.6 2.3 1.6 1 0 0 1 1 1 1 CX module RWP-RK PF02042.15 VBB32587.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain G-alpha PF00503.20 VBB32588.1 - 4.1e-90 302.5 3.1 4.7e-90 302.3 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB32588.1 - 1.4e-11 44.1 1.3 3e-11 43.1 0.9 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB32588.1 - 0.0004 19.8 0.9 0.00058 19.3 0.9 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 VBB32588.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase_Tyr PF07714.17 VBB32589.1 - 1.1e-55 188.8 0.1 1.3e-47 162.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 VBB32589.1 - 8e-34 117.2 0.0 1.5e-25 90.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain SH2 PF00017.24 VBB32589.1 - 0.00065 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 VBB32589.1 - 0.061 12.7 0.1 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 SH2 domain M16C_assoc PF08367.11 VBB32589.1 - 0.12 11.5 0.1 0.26 10.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase M16C associated DUF5134 PF17197.4 VBB32591.1 - 0.085 12.8 1.6 0.23 11.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) DUF4233 PF14017.6 VBB32591.1 - 1.8 9.0 7.9 1.6 9.1 6.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) TFB6 PF17110.5 VBB32592.1 - 0.056 13.2 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pkinase PF00069.25 VBB32593.1 - 1.3e-06 28.0 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Shisa PF13908.6 VBB32595.1 - 1.1 9.5 2.6 0.95 9.7 0.0 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DnaJ PF00226.31 VBB32596.1 - 6.8e-13 48.5 0.5 6.8e-13 48.5 0.5 2.3 2 1 0 2 2 2 1 DnaJ domain DUF3391 PF11871.8 VBB32596.1 - 0.017 15.7 1.7 0.017 15.7 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Asp_Arg_Hydrox PF05118.15 VBB32596.1 - 0.24 11.2 1.4 0.56 10.0 1.4 1.6 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase dCMP_cyt_deam_1 PF00383.23 VBB32597.1 - 6.7e-26 90.1 0.0 9.7e-26 89.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 VBB32597.1 - 2.3e-14 53.3 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase NAD2 PF18782.1 VBB32597.1 - 0.058 13.5 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 SNAD4 PF18750.1 VBB32597.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 PIH1 PF08190.12 VBB32598.1 - 1.5e-25 89.6 0.3 2.9e-25 88.6 0.3 1.3 1 1 0 1 1 1 1 PIH1 N-terminal domain Yip1 PF04893.17 VBB32599.1 - 3.6e-08 33.3 18.5 5.1e-08 32.8 18.5 1.2 1 0 0 1 1 1 1 Yip1 domain DUF4006 PF13179.6 VBB32599.1 - 0.29 11.1 0.2 0.29 11.1 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF3377 PF11857.8 VBB32599.1 - 0.6 10.1 3.0 13 5.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF2059 PF09832.9 VBB32600.1 - 0.12 12.5 0.0 0.44 10.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) Phage_min_cap2 PF06152.11 VBB32600.1 - 0.15 11.0 1.4 0.45 9.3 0.0 2.3 3 0 0 3 3 3 0 Phage minor capsid protein 2 tRNA-synt_1e PF01406.19 VBB32601.1 - 0.14 11.4 0.3 3.3 6.9 0.2 2.0 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Trehalase PF01204.18 VBB32602.1 - 9.3e-141 470.1 9.4 6.1e-74 249.7 3.3 2.0 1 1 1 2 2 2 2 Trehalase GDE_C PF06202.14 VBB32602.1 - 6.4e-05 22.1 3.1 0.00017 20.6 3.1 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.16 VBB32602.1 - 0.16 10.7 4.4 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 C-terminal domain Glyco_transf_25 PF01755.17 VBB32603.1 - 0.12 12.2 5.1 0.1 12.4 0.5 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) F-box PF00646.33 VBB32604.1 - 2.3e-06 27.3 0.1 1e-05 25.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 VBB32604.1 - 1.2e-05 25.1 1.0 4.7e-05 23.2 1.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 VBB32604.1 - 0.00019 21.8 2.0 7.6 7.1 0.0 4.4 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB32604.1 - 0.00037 20.7 2.9 1.6 9.6 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat F-box_4 PF15966.5 VBB32604.1 - 0.0065 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 VBB32604.1 - 0.038 13.8 3.6 2.3 8.1 0.0 4.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 VBB32604.1 - 0.19 11.9 0.4 51 4.3 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Cyclin_N PF00134.23 VBB32605.1 - 3.3e-15 56.0 0.0 5.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 VBB32606.1 - 1e-67 228.3 0.0 1.5e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32606.1 - 5e-31 107.9 0.0 1e-30 106.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32606.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB32606.1 - 0.00011 21.3 0.0 0.0019 17.2 0.0 2.4 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 VBB32606.1 - 0.0077 16.2 0.1 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 VBB32606.1 - 0.013 14.9 0.3 0.046 13.1 0.3 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 VBB32606.1 - 0.043 12.9 0.0 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 Patatin PF01734.22 VBB32607.1 - 1.7e-24 87.2 0.0 2.8e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Malic_M PF03949.15 VBB32608.1 - 5.9e-102 340.4 0.0 7e-102 340.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 VBB32608.1 - 9.9e-48 162.3 0.0 2.1e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 VBB32609.1 - 9.9e-92 306.8 0.1 6.7e-91 304.1 0.1 1.9 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 VBB32609.1 - 5.3e-76 254.5 0.0 8.6e-76 253.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Gemini_AL3 PF01407.17 VBB32610.1 - 0.037 13.9 0.2 0.041 13.7 0.2 1.2 1 0 0 1 1 1 0 Geminivirus AL3 protein Y_phosphatase PF00102.27 VBB32611.1 - 1.5e-36 126.2 1.4 7.8e-21 74.7 0.0 2.4 2 1 1 3 3 3 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 VBB32611.1 - 0.0026 17.9 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 VBB32611.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain YEATS PF03366.16 VBB32612.1 - 5.3e-34 116.0 1.5 5.3e-34 116.0 1.5 1.6 2 0 0 2 2 2 1 YEATS family RPW8 PF05659.11 VBB32612.1 - 0.063 13.0 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Coilin_N PF15862.5 VBB32613.1 - 0.053 13.3 3.9 0.18 11.6 3.9 1.8 1 0 0 1 1 1 0 Coilin N-terminus Selenoprotein_S PF06936.11 VBB32613.1 - 0.28 11.0 7.7 0.052 13.4 3.2 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) ACBP PF00887.19 VBB32615.1 - 9.7e-20 70.6 0.0 2.4e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2951 PF11166.8 VBB32615.1 - 0.0071 16.5 9.7 0.0071 16.5 9.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) YL1 PF05764.13 VBB32615.1 - 0.062 13.4 7.3 0.13 12.4 7.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein ATP-synt_G PF04718.15 VBB32615.1 - 0.092 13.6 0.9 0.27 12.1 0.9 1.8 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit DUF5423 PF17461.2 VBB32615.1 - 0.14 11.0 0.1 0.14 11.0 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Myb_DNA-bind_3 PF12776.7 VBB32615.1 - 0.44 11.5 5.3 0.32 12.0 2.5 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain BAR PF03114.18 VBB32616.1 - 4e-10 39.7 13.6 5e-10 39.4 13.6 1.1 1 0 0 1 1 1 1 BAR domain RasGAP PF00616.19 VBB32616.1 - 0.019 14.7 5.0 0.034 13.8 5.0 1.5 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF1664 PF07889.12 VBB32616.1 - 0.54 10.3 8.7 1.9 8.5 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 VBB32616.1 - 0.55 10.9 4.1 16 6.2 1.2 2.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GIDA_assoc PF13932.6 VBB32616.1 - 1.2 9.3 8.3 1.1 9.4 7.6 1.4 1 1 0 1 1 1 0 GidA associated domain Phlebovirus_NSM PF07246.11 VBB32616.1 - 3 7.1 13.7 0.31 10.4 8.3 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Gp_dh_C PF02800.20 VBB32618.1 - 7.8e-70 233.5 0.0 1.2e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 VBB32618.1 - 5e-33 113.5 0.1 1.2e-32 112.3 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 VBB32618.1 - 0.036 14.1 0.1 0.094 12.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.20 VBB32619.1 - 5.6e-69 230.7 0.0 8.8e-69 230.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 VBB32619.1 - 5.2e-33 113.4 0.1 1.2e-32 112.3 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 VBB32619.1 - 0.029 14.3 0.1 0.094 12.7 0.1 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SET PF00856.28 VBB32620.1 - 1.3e-17 64.7 1.7 1.3e-17 64.7 1.7 3.9 3 2 0 3 3 3 1 SET domain BAH PF01426.18 VBB32620.1 - 1.5e-11 44.2 0.3 6.6e-11 42.1 0.1 2.2 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 VBB32620.1 - 3.7e-08 33.1 7.5 1.7e-07 31.0 7.5 2.3 1 0 0 1 1 1 1 PHD-finger AWS PF17907.1 VBB32620.1 - 0.0063 16.5 12.2 0.033 14.2 12.2 2.4 1 0 0 1 1 1 1 AWS domain C1_2 PF03107.16 VBB32620.1 - 1.4 9.3 8.1 1.5 9.2 5.0 2.8 2 0 0 2 2 2 0 C1 domain DMAP1 PF05499.12 VBB32622.1 - 2.7e-60 203.0 1.8 5.5e-60 202.0 1.8 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 VBB32622.1 - 1.5e-29 102.0 0.7 1.5e-29 102.0 0.7 2.3 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 TcA_TcB_BD PF18276.1 VBB32622.1 - 0.061 12.4 1.7 1.2 8.2 1.9 2.1 2 0 0 2 2 2 0 Tc toxin complex TcA C-terminal TcB-binding domain Methyltransf_24 PF13578.6 VBB32622.1 - 0.083 13.9 0.1 0.3 12.1 0.1 2.0 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.6 VBB32622.1 - 0.18 12.1 2.9 4.3 7.7 2.9 2.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain CENP-B_N PF04218.13 VBB32623.1 - 3.6e-09 36.1 0.2 7.6e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain SUIM_assoc PF16619.5 VBB32623.1 - 0.0038 17.3 17.5 0.033 14.3 5.2 2.9 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 HTH_23 PF13384.6 VBB32623.1 - 0.0083 15.9 0.2 0.019 14.8 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 VBB32623.1 - 0.037 13.6 0.1 0.098 12.2 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2481 PF10654.9 VBB32623.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) HTH_38 PF13936.6 VBB32623.1 - 0.046 13.5 0.3 0.094 12.5 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain COX4 PF02936.14 VBB32623.1 - 0.069 13.2 1.3 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV HTH_IclR PF09339.10 VBB32623.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Requiem_N PF14051.6 VBB32624.1 - 2.4e-26 91.7 1.0 5.6e-26 90.6 1.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. zf-C2H2_11 PF16622.5 VBB32624.1 - 0.0073 16.0 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 VBB32624.1 - 0.047 14.5 1.0 0.047 14.5 1.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB32624.1 - 8.5 7.1 7.0 0.49 11.0 1.1 2.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type SURF1 PF02104.15 VBB32625.1 - 7.4e-40 137.0 0.0 9.4e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family HSP20 PF00011.21 VBB32626.1 - 4.7e-12 45.9 0.2 5.9e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Homeodomain PF00046.29 VBB32627.1 - 3.4e-23 81.2 3.8 5.9e-23 80.5 3.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB32627.1 - 0.022 14.7 0.6 0.073 13.0 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain HAD_2 PF13419.6 VBB32628.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CLP1_P PF16575.5 VBB32629.1 - 6.3e-33 114.2 0.0 1e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 VBB32629.1 - 0.0017 18.4 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 VBB32629.1 - 0.002 17.6 0.1 0.0045 16.4 0.0 1.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 VBB32629.1 - 0.022 15.1 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB32629.1 - 0.036 14.5 0.0 0.074 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 VBB32629.1 - 0.15 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Homeodomain PF00046.29 VBB32631.1 - 5.7e-11 42.1 0.2 9.3e-11 41.4 0.2 1.3 1 0 0 1 1 1 1 Homeodomain Peptidase_M8 PF01457.16 VBB32632.1 - 1e-07 31.1 0.0 1.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin VWC PF00093.18 VBB32633.1 - 0.00078 19.7 18.5 0.0013 19.0 18.5 1.4 1 0 0 1 1 1 1 von Willebrand factor type C domain TMEM154 PF15102.6 VBB32633.1 - 0.14 12.1 0.3 0.23 11.4 0.1 1.5 1 1 0 1 1 1 0 TMEM154 protein family zf-RING_5 PF14634.6 VBB32634.1 - 2e-08 34.0 11.0 3.8e-08 33.1 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 VBB32634.1 - 0.0028 17.5 7.0 0.006 16.4 7.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 VBB32634.1 - 0.037 13.9 9.1 0.087 12.7 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 VBB32634.1 - 0.04 13.9 3.6 0.11 12.6 3.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Endostatin PF06482.11 VBB32634.1 - 0.068 12.6 6.2 0.091 12.2 6.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin zf-C3HC4_2 PF13923.6 VBB32634.1 - 0.23 11.3 8.9 0.69 9.8 8.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 VBB32634.1 - 0.37 11.0 5.1 0.72 10.0 5.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 VBB32634.1 - 0.57 10.1 5.6 0.45 10.4 3.1 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 VBB32634.1 - 1.1 9.7 9.9 2 8.8 9.9 1.5 1 0 0 1 1 1 0 Ring finger domain Exonuc_VII_L PF02601.15 VBB32634.1 - 4.3 6.8 10.2 5.7 6.4 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 VBB32635.1 - 3e-40 138.3 1.5 1e-39 136.5 1.5 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32635.1 - 4.4e-19 68.8 0.3 5.9e-19 68.4 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32635.1 - 3.5e-08 33.1 0.0 4.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF3314 PF11771.8 VBB32635.1 - 0.12 12.5 1.2 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) SNAP PF14938.6 VBB32636.1 - 2.3e-13 50.2 5.7 3.8e-13 49.5 5.7 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 VBB32636.1 - 8.9e-06 25.9 0.4 0.0014 18.9 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 VBB32636.1 - 0.00018 21.0 0.1 0.00021 20.8 0.1 1.1 1 0 0 1 1 1 1 MalT-like TPR region DUF4810 PF16068.5 VBB32636.1 - 0.0024 18.4 0.2 0.0068 16.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) TPR_1 PF00515.28 VBB32636.1 - 0.0055 16.5 2.1 1.1 9.2 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF2989 PF11207.8 VBB32636.1 - 0.0065 16.3 0.6 0.033 14.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2989) TPR_7 PF13176.6 VBB32636.1 - 0.0097 15.9 0.1 4.6 7.5 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB32636.1 - 0.017 15.2 2.0 10 6.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32636.1 - 0.033 14.7 0.3 0.21 12.1 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 VBB32636.1 - 0.033 13.9 1.5 0.33 10.6 0.6 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain Foie-gras_1 PF11817.8 VBB32636.1 - 0.1 12.2 0.5 0.14 11.7 0.1 1.4 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_8 PF13181.6 VBB32636.1 - 0.11 12.8 2.3 12 6.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4806 PF16064.5 VBB32637.1 - 0.0081 16.4 0.1 0.097 13.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) FlaC_arch PF05377.11 VBB32637.1 - 0.042 14.3 0.8 1.8 9.0 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Snurportin1 PF11538.8 VBB32637.1 - 0.1 12.8 0.1 0.31 11.2 0.1 1.9 1 0 0 1 1 1 0 Snurportin1 Beta-lactamase PF00144.24 VBB32637.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase Xan_ur_permease PF00860.20 VBB32638.1 - 6.1e-103 344.5 29.9 6.1e-103 344.5 29.9 1.4 2 0 0 2 2 2 1 Permease family ADH_zinc_N PF00107.26 VBB32639.1 - 3.6e-22 78.7 0.0 5.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 VBB32639.1 - 3.6e-09 37.8 0.1 7.1e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 VBB32639.1 - 5e-08 32.8 0.1 9.7e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TGT PF01702.18 VBB32640.1 - 2.6e-30 105.8 0.0 3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TGT PF01702.18 VBB32641.1 - 5.4e-96 321.8 0.3 6.1e-96 321.6 0.3 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M14 PF00246.24 VBB32642.1 - 4.1e-74 250.0 0.0 5.6e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 VBB32642.1 - 3.3e-14 52.9 0.0 7.6e-14 51.8 0.1 1.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 VBB32642.1 - 2.2e-06 27.6 0.1 4.7e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 VBB32642.1 - 0.0026 17.6 0.1 0.0056 16.5 0.1 1.5 1 0 0 1 1 1 1 PEGA domain phage_tail_N PF08400.10 VBB32642.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal AstE_AspA PF04952.14 VBB32642.1 - 0.088 11.9 0.0 0.21 10.6 0.0 1.7 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family SdrD_B PF17210.3 VBB32642.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 SdrD B-like domain RINGv PF12906.7 VBB32643.1 - 8.6e-14 51.4 9.1 8.6e-14 51.4 9.1 2.3 2 0 0 2 2 2 1 RING-variant domain SUR7 PF06687.12 VBB32643.1 - 0.092 12.4 8.7 0.04 13.5 7.0 1.4 1 1 0 1 1 1 0 SUR7/PalI family Ion_trans PF00520.31 VBB32644.1 - 2.1e-101 338.2 25.7 1.6e-51 174.9 4.1 3.1 2 1 0 2 2 2 2 Ion transport protein FAM176 PF14851.6 VBB32644.1 - 0.00015 21.4 0.2 0.24 11.1 0.0 2.7 2 0 0 2 2 2 2 FAM176 family DUF3935 PF13071.6 VBB32644.1 - 0.0091 16.5 2.6 1.5 9.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3935) DPM3 PF08285.11 VBB32644.1 - 0.01 16.0 2.1 0.39 11.0 0.2 3.1 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2938 PF11158.8 VBB32644.1 - 0.025 14.1 0.5 6.1 6.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2938) DUF1221 PF06760.11 VBB32644.1 - 0.11 12.0 1.9 0.16 11.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1221) PKD_channel PF08016.12 VBB32644.1 - 3.3 6.3 35.7 0.14 10.8 0.7 4.7 4 2 1 5 5 5 0 Polycystin cation channel AP_endonuc_2 PF01261.24 VBB32645.1 - 1.8e-05 24.3 0.1 5.8e-05 22.6 0.0 1.7 1 1 0 2 2 2 1 Xylose isomerase-like TIM barrel Fe_bilin_red PF05996.12 VBB32645.1 - 0.025 14.3 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Collagen PF01391.18 VBB32646.1 - 6.4e-25 86.7 75.0 4.7e-10 39.1 25.6 3.7 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32646.1 - 5.2e-16 58.4 0.1 7.3e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 VBB32647.1 - 0.00037 20.0 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 VBB32647.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Bromodomain PF00439.25 VBB32648.1 - 1.5e-22 79.5 0.5 3.2e-22 78.4 0.5 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 VBB32648.1 - 1.2e-19 70.0 27.0 4.9e-11 42.3 7.8 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 VBB32648.1 - 0.0089 15.6 15.3 0.066 12.8 5.2 2.6 2 0 0 2 2 2 2 PHD-finger PHD_4 PF16866.5 VBB32648.1 - 0.087 12.9 17.4 1.2 9.3 3.5 3.1 2 0 0 2 2 2 0 PHD-finger DUF3716 PF12511.8 VBB32648.1 - 2 8.6 13.8 0.87 9.7 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Collagen PF01391.18 VBB32649.1 - 2.1e-07 30.6 19.6 2.5e-07 30.4 19.6 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) I-set PF07679.16 VBB32650.1 - 0.054 13.6 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Innexin PF00876.18 VBB32651.1 - 1.4e-71 241.7 11.5 4e-68 230.3 8.2 2.0 1 1 1 2 2 2 2 Innexin DEAD_2 PF06733.15 VBB32653.1 - 2.2e-34 118.6 0.9 3.4e-34 118.0 0.9 1.2 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 VBB32653.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB32653.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase MRP-S26 PF14943.6 VBB32654.1 - 1.2e-48 165.2 13.5 1.7e-48 164.7 13.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 WH2 PF02205.20 VBB32654.1 - 3.1e-08 33.2 0.3 8.4e-08 31.8 0.3 1.8 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 VBB32654.1 - 0.0009 18.8 1.1 0.0009 18.8 1.1 5.5 5 2 1 7 7 7 1 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.8 VBB32654.1 - 0.051 13.0 0.3 0.051 13.0 0.3 3.8 4 1 1 5 5 5 0 Nepovirus subgroup A polyprotein NPHI_C PF08469.10 VBB32654.1 - 0.21 11.6 1.4 0.34 10.9 1.4 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal AAA_23 PF13476.6 VBB32654.1 - 1.6 9.2 9.7 2.5 8.6 9.7 1.2 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 VBB32654.1 - 2.5 5.9 4.4 3.9 5.3 4.4 1.2 1 0 0 1 1 1 0 Prominin DUF883 PF05957.13 VBB32654.1 - 3.3 8.4 5.8 8 7.1 5.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Peptidase_S46 PF10459.9 VBB32654.1 - 7.2 5.1 8.6 10 4.6 8.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Med11 PF10280.9 VBB32655.1 - 2.9e-12 47.2 1.3 3.5e-12 46.9 1.3 1.2 1 0 0 1 1 1 1 Mediator complex protein Interferon PF00143.19 VBB32655.1 - 0.0042 17.3 2.7 0.27 11.4 0.4 2.1 1 1 1 2 2 2 2 Interferon alpha/beta domain Golgin_A5 PF09787.9 VBB32655.1 - 0.0049 16.4 1.4 0.006 16.1 1.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DHR10 PF18595.1 VBB32655.1 - 0.01 15.9 1.1 0.01 15.9 1.1 2.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Acyl_transf_3 PF01757.22 VBB32656.1 - 1.1e-07 31.2 9.4 1.2e-07 31.1 9.4 1.0 1 0 0 1 1 1 1 Acyltransferase family Proteasome PF00227.26 VBB32658.1 - 2.8e-39 134.6 0.3 3.7e-39 134.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit REV1_C PF16727.5 VBB32659.1 - 0.15 12.5 2.2 19 5.7 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Caudo_TAP PF02413.17 VBB32659.1 - 2 8.6 8.0 5.6 7.1 3.8 2.4 1 1 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Homeobox_KN PF05920.11 VBB32660.1 - 1.5e-18 66.3 0.1 3.6e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Meis_PKNOX_N PF16493.5 VBB32660.1 - 3.3e-15 56.2 0.1 1.1e-14 54.5 0.1 1.8 2 0 0 2 2 2 1 N-terminal of Homeobox Meis and PKNOX1 Homeodomain PF00046.29 VBB32660.1 - 3.7e-07 29.9 0.2 9.1e-07 28.6 0.2 1.7 1 0 0 1 1 1 1 Homeodomain DUF2701 PF10857.8 VBB32660.1 - 0.095 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) GHMP_kinases_N PF00288.26 VBB32661.1 - 5.7e-14 52.1 0.3 1.3e-13 51.0 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 VBB32661.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Collagen PF01391.18 VBB32662.1 - 1.8e-27 94.9 86.4 8.3e-10 38.3 33.5 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32662.1 - 0.64 10.1 9.2 6.9 6.8 9.2 2.0 1 1 0 1 1 1 0 Nematode cuticle collagen N-terminal domain BAR PF03114.18 VBB32663.1 - 4.6e-12 46.1 6.5 6e-12 45.7 6.5 1.1 1 0 0 1 1 1 1 BAR domain Bcr-Abl_Oligo PF09036.10 VBB32663.1 - 0.0053 16.7 0.7 0.013 15.5 0.7 1.7 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain Exonuc_VII_L PF02601.15 VBB32663.1 - 5.2 6.5 7.7 7.4 6.0 7.4 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ephrin PF00812.17 VBB32664.1 - 0.00048 20.1 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Ephrin NHL PF01436.21 VBB32665.1 - 4.8e-30 102.1 3.7 1.5e-08 34.2 0.1 4.7 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 VBB32665.1 - 2.7e-07 30.4 0.1 0.0066 16.1 0.0 3.4 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 VBB32665.1 - 0.00054 20.0 0.0 0.12 12.3 0.0 2.5 1 1 1 2 2 2 2 Esterase-like activity of phytase Arylesterase PF01731.20 VBB32665.1 - 0.018 15.2 1.6 0.74 10.0 0.0 3.4 4 1 0 4 4 4 0 Arylesterase Reg_prop PF07494.11 VBB32665.1 - 0.045 14.0 0.1 32 5.2 0.1 4.0 3 0 0 3 3 3 0 Two component regulator propeller LRR_8 PF13855.6 VBB32666.1 - 9.2e-14 51.0 14.4 1.1e-06 28.3 7.0 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 VBB32666.1 - 1.1e-13 51.1 19.1 2.7e-06 27.6 0.7 4.7 2 1 5 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB32666.1 - 3e-07 30.1 3.2 5.1e-06 26.1 2.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 VBB32666.1 - 0.0011 18.9 10.3 0.027 14.5 0.4 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 VBB32666.1 - 1.2 10.0 13.1 98 4.1 0.0 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat C1_1 PF00130.22 VBB32667.1 - 1.8e-30 104.6 19.7 2.8e-17 62.3 9.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 VBB32667.1 - 3.1e-16 59.6 0.0 5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain C1_2 PF03107.16 VBB32667.1 - 0.0022 18.2 16.7 0.039 14.3 2.5 3.1 3 0 0 3 3 3 2 C1 domain FYVE_2 PF02318.16 VBB32667.1 - 0.0081 16.4 9.1 0.19 12.0 2.1 2.4 1 1 0 2 2 2 2 FYVE-type zinc finger Zf_RING PF16744.5 VBB32667.1 - 0.11 12.6 8.3 0.1 12.8 2.2 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger DZR PF12773.7 VBB32667.1 - 0.15 12.1 8.3 0.74 9.9 0.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 VBB32667.1 - 0.31 11.0 16.0 0.71 9.8 6.8 2.6 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 VBB32667.1 - 0.63 10.0 11.7 0.14 12.2 3.9 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-ribbon_3 PF13248.6 VBB32667.1 - 1.8 8.0 5.5 7.8 6.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain MIP PF00230.20 VBB32668.1 - 3.9e-23 82.4 1.5 4.4e-23 82.2 1.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein RdRP PF05183.12 VBB32669.1 - 5.1e-86 289.6 0.0 9.7e-86 288.7 0.0 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase Pkinase PF00069.25 VBB32669.1 - 3.4e-13 49.6 0.0 6.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32669.1 - 3.2e-10 39.7 0.0 5.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CUE PF02845.16 VBB32669.1 - 0.00046 19.8 0.0 0.0014 18.3 0.0 1.9 1 0 0 1 1 1 1 CUE domain Orai-1 PF07856.12 VBB32670.1 - 2.5e-47 160.8 7.5 2.5e-47 160.8 7.5 1.6 2 0 0 2 2 2 1 Mediator of CRAC channel activity DUF4805 PF16063.5 VBB32670.1 - 0.11 11.8 12.3 0.39 10.0 6.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4805) FSA_C PF10479.9 VBB32670.1 - 1.2 7.2 15.5 1.8 6.6 15.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 VBB32670.1 - 5.7 6.9 47.6 0.16 12.0 40.3 2.1 3 0 0 3 3 3 0 Mucin-like glycoprotein LNS2 PF08235.13 VBB32672.1 - 4.3e-91 304.4 0.0 1.1e-90 303.1 0.0 1.7 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 VBB32672.1 - 4.1e-39 132.7 0.0 7.7e-39 131.8 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region FH2 PF02181.23 VBB32673.1 - 6.1e-69 232.9 10.0 6.1e-69 232.9 10.0 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 VBB32673.1 - 1.1e-35 123.0 0.0 1.1e-35 123.0 0.0 3.4 3 1 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 VBB32673.1 - 2.7e-18 66.2 3.4 2.7e-18 66.2 3.4 3.1 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Taxilin PF09728.9 VBB32673.1 - 0.51 9.5 17.4 0.028 13.6 1.3 3.3 3 0 0 3 3 3 0 Myosin-like coiled-coil protein SET PF00856.28 VBB32675.1 - 2e-05 25.1 2.8 7.9e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 SET domain TFIIA PF03153.13 VBB32675.1 - 0.015 15.3 17.3 0.022 14.7 17.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3012 PF11216.8 VBB32675.1 - 0.062 13.3 1.0 0.16 12.1 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Suf PF05843.14 VBB32675.1 - 0.19 11.7 7.9 0.32 10.9 7.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Coilin_N PF15862.5 VBB32675.1 - 1.1 9.1 9.4 2 8.2 9.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUF4770 PF15994.5 VBB32675.1 - 9.4 6.4 16.3 4.6 7.5 11.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Pkinase PF00069.25 VBB32677.1 - 1.5e-17 63.9 0.1 2.5e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32677.1 - 1.2e-08 34.6 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_8 PF05148.15 VBB32678.1 - 4.4e-87 291.5 1.3 8.3e-87 290.6 0.2 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase NOG1_N PF17835.1 VBB32678.1 - 5.6e-50 169.4 3.1 5.6e-50 169.4 3.1 2.6 2 0 0 2 2 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 VBB32678.1 - 3.3e-25 87.6 0.2 8e-25 86.4 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 VBB32678.1 - 6.1e-22 77.4 1.6 1.4e-21 76.2 1.6 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 VBB32678.1 - 2.1e-16 60.0 0.0 6.7e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_11 PF08241.12 VBB32678.1 - 2e-08 34.8 0.9 1.9e-07 31.6 0.0 3.2 3 1 0 3 3 2 1 Methyltransferase domain FeoB_N PF02421.18 VBB32678.1 - 1.2e-07 31.4 0.2 4.5e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Methyltransf_25 PF13649.6 VBB32678.1 - 2e-06 28.4 0.1 0.00079 20.1 0.1 3.9 2 1 0 2 2 2 1 Methyltransferase domain RsgA_GTPase PF03193.16 VBB32678.1 - 0.00031 20.7 0.1 0.27 11.1 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 VBB32678.1 - 0.0014 18.0 0.3 0.011 15.1 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.23 VBB32678.1 - 0.0023 18.0 1.9 3.5 7.7 0.0 3.8 4 0 0 4 4 4 2 Dynamin family Methyltransf_12 PF08242.12 VBB32678.1 - 0.028 15.1 0.6 8.6 7.2 0.0 4.0 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 VBB32678.1 - 0.037 13.8 4.5 0.58 9.9 0.3 3.4 2 2 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.6 VBB32678.1 - 0.058 13.7 0.2 3 8.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain MTS PF05175.14 VBB32678.1 - 0.1 12.2 0.4 2.6 7.6 0.1 2.6 1 1 1 2 2 2 0 Methyltransferase small domain AAA_16 PF13191.6 VBB32678.1 - 0.14 12.6 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Homeodomain PF00046.29 VBB32679.1 - 7.8e-21 73.7 3.1 1.4e-20 72.8 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB32679.1 - 0.009 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Hist_deacetyl PF00850.19 VBB32680.1 - 1.6e-38 133.0 2.8 2.2e-38 132.5 2.8 1.2 1 0 0 1 1 1 1 Histone deacetylase domain An_peroxidase PF03098.15 VBB32681.1 - 1.4e-97 327.5 0.0 1.8e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PAP2_C PF14360.6 VBB32683.1 - 7.6e-21 74.4 12.2 7.6e-21 74.4 12.2 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 VBB32683.1 - 0.0012 18.6 5.3 0.0012 18.6 5.3 2.5 2 1 0 2 2 2 1 PAP2 superfamily PIG-P PF08510.12 VBB32683.1 - 0.59 10.1 3.9 1.1 9.1 0.1 2.7 2 1 0 2 2 2 0 PIG-P Snf7 PF03357.21 VBB32685.1 - 1e-40 139.2 31.4 1e-40 139.2 31.4 1.5 2 0 0 2 2 2 1 Snf7 Peptidase_M57 PF12388.8 VBB32685.1 - 0.09 12.4 1.8 0.16 11.5 1.0 1.8 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF4845 PF16137.5 VBB32685.1 - 0.76 10.7 11.8 0.28 12.1 3.3 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4845) 2OG-FeII_Oxy_2 PF13532.6 VBB32686.1 - 5.2e-09 36.6 0.4 1.7e-07 31.6 0.3 2.1 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ammonium_transp PF00909.21 VBB32687.1 - 5.3e-54 183.4 11.0 1.9e-51 175.0 9.8 2.1 1 1 1 2 2 2 2 Ammonium Transporter Family CDP-OH_P_tran_2 PF08009.11 VBB32687.1 - 0.2 11.6 1.1 0.48 10.4 1.1 1.6 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 SH3_1 PF00018.28 VBB32688.1 - 5.3e-12 45.1 0.0 1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB32688.1 - 2.5e-11 43.3 0.0 5.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB32688.1 - 2e-09 36.9 0.0 3.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 VBB32688.1 - 7e-09 35.9 0.1 7e-09 35.9 0.1 3.4 4 1 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain GARP PF16731.5 VBB32688.1 - 0.0054 16.4 1.9 0.013 15.2 1.9 1.6 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma SH3_10 PF17902.1 VBB32688.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Headcase PF16002.5 VBB32689.1 - 8.1e-52 175.6 3.2 1.2e-51 175.0 3.2 1.2 1 0 0 1 1 1 1 Headcase protein TSP_1 PF00090.19 VBB32690.1 - 3e-06 27.3 11.0 4.9e-06 26.7 11.0 1.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain Astacin PF01400.24 VBB32691.1 - 2.5e-66 223.0 1.8 5.7e-66 221.8 1.8 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Endopep_inhib PF16800.5 VBB32691.1 - 0.011 15.6 2.0 0.026 14.4 2.0 1.5 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor Peptidase_M10 PF00413.24 VBB32691.1 - 0.11 12.3 0.6 0.48 10.2 0.3 1.8 1 1 0 2 2 2 0 Matrixin RabGAP-TBC PF00566.18 VBB32692.1 - 4e-54 183.5 3.8 1e-53 182.2 3.8 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PWWP PF00855.17 VBB32693.1 - 1.4e-06 28.6 0.0 3.4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 PWWP domain WIF PF02019.18 VBB32694.1 - 1e-26 93.2 0.0 1.1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 WIF domain DUF5626 PF18540.1 VBB32694.1 - 0.078 13.5 0.2 0.13 12.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5626) Fcf1 PF04900.12 VBB32695.1 - 4.7e-24 84.7 2.4 8.2e-24 83.9 0.3 2.2 2 0 0 2 2 2 1 Fcf1 CX9C PF16860.5 VBB32695.1 - 0.017 15.1 0.8 0.065 13.3 0.8 2.0 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Peroxin-3 PF04882.12 VBB32696.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.4 1 1 0 1 1 1 0 Peroxin-3 PGI PF00342.19 VBB32697.1 - 3.7e-46 157.8 0.0 4.1e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PASTA PF03793.19 VBB32697.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 PASTA domain UQ_con PF00179.26 VBB32698.1 - 2.2e-49 166.7 0.0 3.9e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med9 PF07544.13 VBB32698.1 - 0.096 12.8 0.4 0.096 12.8 0.4 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 UDPG_MGDP_dh_N PF03721.14 VBB32699.1 - 5.9e-64 215.1 0.0 9.4e-64 214.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 VBB32699.1 - 8.1e-28 96.9 0.1 2.1e-24 85.9 0.1 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 VBB32699.1 - 2.4e-27 95.0 0.0 5.7e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 VBB32699.1 - 0.0069 16.6 0.0 0.092 12.9 0.0 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 VBB32699.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 VBB32699.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RasGAP PF00616.19 VBB32700.1 - 1.5e-19 70.5 9.8 4.2e-15 56.0 0.0 3.2 3 2 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 VBB32700.1 - 3.3e-10 40.4 2.1 1.3e-09 38.5 0.1 2.8 4 0 0 4 4 4 1 PH domain PH_6 PF15406.6 VBB32700.1 - 0.00019 21.7 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 VBB32700.1 - 0.095 13.1 0.2 1 9.7 0.0 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain F-box PF00646.33 VBB32700.1 - 0.4 10.6 2.7 28 4.7 0.1 3.4 3 0 0 3 3 3 0 F-box domain Thymosin PF01290.20 VBB32701.1 - 6.8e-16 57.7 0.3 3.5e-08 33.1 0.1 2.1 2 0 0 2 2 2 2 Thymosin beta-4 family ANAPC3 PF12895.7 VBB32702.1 - 4.1e-21 75.0 24.6 3.1e-15 56.1 9.2 4.9 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 VBB32702.1 - 3.8e-20 70.3 17.6 0.0042 17.1 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 VBB32702.1 - 2.4e-19 68.3 9.8 2.8e-05 23.8 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32702.1 - 3.3e-19 69.2 7.7 2.6e-07 31.0 0.3 7.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 VBB32702.1 - 4.7e-16 57.6 3.3 0.14 12.4 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB32702.1 - 2.3e-14 52.6 8.8 0.00079 19.6 1.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB32702.1 - 6.5e-13 48.1 0.0 0.0093 15.6 0.0 5.4 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 VBB32702.1 - 8.5e-11 42.3 10.3 0.4 11.4 0.2 7.9 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB32702.1 - 5.7e-09 36.1 12.1 0.059 14.2 0.0 7.9 6 1 2 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB32702.1 - 2.5e-08 34.0 13.6 0.023 15.3 0.2 8.2 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB32702.1 - 1.4e-07 31.6 5.4 0.29 11.3 0.2 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB32702.1 - 1.7e-07 31.4 22.8 1.2 9.5 0.0 8.1 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_15 PF13429.6 VBB32702.1 - 5.7e-06 25.7 0.8 1.4 8.1 0.1 4.1 3 2 1 4 4 4 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 VBB32702.1 - 0.00097 19.2 5.8 0.016 15.2 1.3 2.9 3 0 0 3 3 3 1 Putative TPR-like repeat HrpB1_HrpK PF09613.10 VBB32702.1 - 0.0085 15.7 3.1 0.44 10.2 0.1 3.3 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) ChAPs PF09295.10 VBB32702.1 - 0.044 12.8 0.3 3 6.8 0.2 2.7 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 VBB32702.1 - 1 9.8 4.1 0.89 9.9 0.5 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 VBB32702.1 - 6 7.8 0.0 6 7.8 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ODC_AZ PF02100.17 VBB32703.1 - 4.6e-13 49.2 0.0 5.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Tam41_Mmp37 PF09139.11 VBB32704.1 - 4.3e-46 157.8 0.1 4.7e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF573 PF04504.14 VBB32705.1 - 0.091 13.4 1.9 9.7 6.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Beta-lactamase PF00144.24 VBB32706.1 - 3.2e-09 36.5 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Biopterin_H PF00351.21 VBB32707.1 - 1.5e-98 329.9 5.4 9e-97 324.1 5.4 2.1 1 1 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Pkinase PF00069.25 VBB32707.1 - 4.1e-22 78.8 0.0 8.5e-22 77.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32707.1 - 3e-14 52.9 0.0 4.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_11 PF08279.12 VBB32707.1 - 0.0047 16.8 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 HTH domain Tyrosinase PF00264.20 VBB32709.1 - 2.1e-33 116.5 0.9 2.1e-33 116.5 0.9 2.3 2 1 0 2 2 2 1 Common central domain of tyrosinase ShK PF01549.24 VBB32709.1 - 1.8e-11 44.4 30.9 3.1e-07 30.8 14.4 4.3 5 0 0 5 5 5 2 ShK domain-like ubiquitin PF00240.23 VBB32710.1 - 2.9e-32 110.3 0.9 4.6e-32 109.6 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 VBB32710.1 - 2.8e-26 91.4 4.2 6.6e-26 90.2 4.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 VBB32710.1 - 1.3e-15 56.9 0.4 2.6e-15 56.0 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 VBB32710.1 - 9.1e-05 22.8 0.5 0.00076 19.9 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 VBB32710.1 - 0.0014 18.7 0.7 0.0037 17.3 0.7 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_ribbon_SprT PF17283.2 VBB32710.1 - 0.0058 16.5 0.5 0.012 15.5 0.5 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain TBK1_ULD PF18396.1 VBB32710.1 - 0.0066 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 VBB32710.1 - 0.033 14.4 0.7 0.059 13.6 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF2407 PF10302.9 VBB32710.1 - 0.097 13.2 0.6 0.15 12.6 0.6 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.12 VBB32710.1 - 0.34 9.5 3.1 7.9 5.0 0.3 2.2 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain CTP_transf_1 PF01148.20 VBB32711.1 - 0.0015 18.3 4.4 0.0022 17.8 4.4 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family YhhN PF07947.14 VBB32711.1 - 0.0033 17.1 4.5 0.0056 16.3 4.5 1.3 1 0 0 1 1 1 1 YhhN family LtrA PF06772.11 VBB32711.1 - 0.079 12.2 3.1 0.032 13.5 0.7 1.5 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) LIM PF00412.22 VBB32712.1 - 1.7e-11 44.1 16.6 2.2e-11 43.8 16.6 1.1 1 0 0 1 1 1 1 LIM domain zf_UBZ PF18439.1 VBB32712.1 - 0.64 9.7 0.1 0.64 9.7 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 VBB32712.1 - 0.91 9.8 10.8 2.2 8.6 10.9 1.7 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.6 VBB32712.1 - 3.6 7.4 14.4 0.43 10.4 0.6 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 VBB32712.1 - 8.2 6.6 15.7 2.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Spc7 PF08317.11 VBB32713.1 - 0.0051 15.7 28.6 0.0051 15.7 28.6 4.2 3 1 0 4 4 4 3 Spc7 kinetochore protein Cytochrome_C7 PF14522.6 VBB32713.1 - 4.4 7.4 6.5 1.3 9.1 0.8 3.1 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF236 PF03057.14 VBB32715.1 - 1.1e-74 246.0 28.5 3.7e-16 58.8 1.2 5.3 5 0 0 5 5 5 5 DUF236 repeat DUF2722 PF10846.8 VBB32715.1 - 0.0063 15.5 0.1 0.0063 15.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 VBB32715.1 - 0.3 10.7 9.6 0.4 10.3 9.6 1.1 1 0 0 1 1 1 0 Spt20 family TMEM51 PF15345.6 VBB32715.1 - 0.42 10.4 2.6 0.63 9.8 2.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 YccV-like PF08755.11 VBB32717.1 - 5.1e-25 87.8 0.1 8.1e-25 87.2 0.1 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like pEK499_p136 PF18736.1 VBB32717.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 HEPN pEK499 p136 DUF2124 PF09897.9 VBB32717.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) RCC1 PF00415.18 VBB32718.1 - 3.3e-48 162.1 12.1 4.4e-13 49.6 0.2 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB32718.1 - 9e-39 130.5 19.7 1.9e-08 33.9 0.9 7.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 VBB32718.1 - 0.048 13.4 0.2 12 5.5 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF5071 PF16804.5 VBB32719.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) Innexin PF00876.18 VBB32720.1 - 4.5e-41 141.3 2.6 1.3e-37 129.9 1.3 2.1 2 0 0 2 2 2 2 Innexin SGIII PF15467.6 VBB32720.1 - 0.13 11.5 0.3 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Secretogranin-3 Ank_2 PF12796.7 VBB32721.1 - 1.3e-16 61.0 1.7 1.7e-07 31.8 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Death PF00531.22 VBB32721.1 - 1.4e-16 60.5 0.1 4.6e-16 58.7 0.1 2.0 1 0 0 1 1 1 1 Death domain Ank_5 PF13857.6 VBB32721.1 - 1.6e-15 57.0 0.3 7.1e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 VBB32721.1 - 3.9e-15 56.0 1.6 1.6e-06 28.5 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB32721.1 - 2.7e-13 49.7 4.9 0.0015 18.9 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 VBB32721.1 - 2.2e-10 39.8 3.4 0.0077 16.7 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat COR PF16095.5 VBB32721.1 - 4.6e-07 29.9 0.0 8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 VBB32721.1 - 0.00017 21.8 0.0 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase eIF-1a PF01176.19 VBB32722.1 - 6.6e-13 48.3 0.1 1e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 SDA1 PF05285.12 VBB32722.1 - 5.8 6.2 10.2 8.2 5.7 10.2 1.2 1 0 0 1 1 1 0 SDA1 Ank_2 PF12796.7 VBB32723.1 - 2.2e-27 95.4 10.5 1.2e-13 51.4 0.2 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 VBB32723.1 - 1.9e-15 56.5 10.9 4.1e-05 23.8 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 VBB32723.1 - 1.8e-14 53.9 5.1 2.1e-09 37.7 0.4 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB32723.1 - 4.7e-14 51.1 3.4 0.00067 19.9 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 VBB32723.1 - 5.1e-14 52.2 7.2 1.1e-06 28.8 0.6 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ilm1 PF10311.9 VBB32723.1 - 0.062 12.9 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF5517 PF17639.2 VBB32724.1 - 0.0089 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5517) ThiF PF00899.21 VBB32724.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family RhoGEF PF00621.20 VBB32725.1 - 2.2e-24 86.7 0.2 2.2e-24 86.7 0.2 2.9 2 2 1 3 3 3 1 RhoGEF domain PH_13 PF16652.5 VBB32725.1 - 1.4e-12 47.7 0.3 4.8e-12 46.0 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 VBB32725.1 - 3.9e-05 24.1 0.6 0.00019 21.9 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_5 PF15405.6 VBB32725.1 - 0.00043 20.4 0.2 0.0023 18.0 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 VBB32725.1 - 0.00049 19.9 0.5 0.0019 18.0 0.5 2.0 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 VBB32725.1 - 0.014 15.7 0.4 0.039 14.2 0.4 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 VBB32725.1 - 0.089 12.8 5.7 0.066 13.2 2.4 2.3 2 1 0 2 2 2 0 PH domain Astacin PF01400.24 VBB32726.1 - 2.7e-69 232.6 0.2 2.7e-69 232.6 0.2 3.2 2 1 0 3 3 3 1 Astacin (Peptidase family M12A) PIN_4 PF13638.6 VBB32726.1 - 1.7e-17 63.9 0.0 5.9e-17 62.2 0.0 2.0 1 0 0 1 1 1 1 PIN domain ShK PF01549.24 VBB32726.1 - 5.9e-08 33.1 17.6 5.3e-07 30.1 5.9 3.2 3 0 0 3 3 3 2 ShK domain-like Patatin PF01734.22 VBB32726.1 - 0.056 13.6 0.0 0.15 12.3 0.0 1.8 1 1 0 1 1 1 0 Patatin-like phospholipase Mucin PF01456.17 VBB32726.1 - 0.68 9.9 43.5 1.4 8.9 43.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 VBB32726.1 - 8.3 4.4 16.7 13 3.8 16.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Nkap_C PF06047.11 VBB32728.1 - 2.6e-41 139.9 3.7 2.6e-41 139.9 3.7 3.9 3 1 1 4 4 4 1 NF-kappa-B-activating protein C-terminal domain OAD_gamma PF04277.13 VBB32728.1 - 8.1 7.1 7.5 28 5.4 7.5 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ZU5 PF00791.20 VBB32730.1 - 2.9e-31 107.7 0.0 8.6e-31 106.2 0.0 1.9 1 0 0 1 1 1 1 ZU5 domain PDZ PF00595.24 VBB32730.1 - 4.5e-11 43.0 0.8 1.3e-10 41.5 0.8 1.8 1 0 0 1 1 1 1 PDZ domain Guanylate_kin PF00625.21 VBB32730.1 - 4.2e-09 36.3 0.1 4.2e-09 36.3 0.1 2.6 2 1 1 3 3 3 1 Guanylate kinase PDZ_2 PF13180.6 VBB32730.1 - 7.9e-07 29.3 0.2 1.9e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB32730.1 - 2.4e-06 27.3 0.2 8.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 VBB32730.1 - 0.00052 19.6 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AreA_N PF07573.11 VBB32730.1 - 0.42 11.3 6.2 1.7 9.3 0.4 3.7 2 1 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus ANAPC_CDC26 PF10471.9 VBB32730.1 - 1.9 9.3 19.3 0.15 12.9 12.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FA_desaturase PF00487.24 VBB32732.1 - 2.6e-11 43.9 3.0 4e-11 43.3 3.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PDZ PF00595.24 VBB32733.1 - 3.1e-10 40.3 0.0 6.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB32733.1 - 1e-06 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB32733.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 PDZ domain ARPC4 PF05856.12 VBB32734.1 - 5.1e-74 247.4 4.7 5.1e-74 247.4 4.7 2.2 2 0 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) Integrase_H2C2 PF17921.1 VBB32734.1 - 1.1e-10 41.5 2.1 1.9e-10 40.7 1.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain DUF1759 PF03564.15 VBB32734.1 - 4.4e-07 29.9 1.5 6.5e-07 29.4 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) zf-H2C2 PF09337.10 VBB32734.1 - 8.5e-07 29.1 1.9 1.4e-05 25.2 0.3 2.8 3 0 0 3 3 3 1 H2C2 zinc finger eIF3g PF12353.8 VBB32734.1 - 0.029 14.8 0.3 0.081 13.3 0.3 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Get5_C PF18514.1 VBB32734.1 - 0.071 12.8 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Get5 C-terminal domain GvpK PF05121.12 VBB32734.1 - 0.096 12.7 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Gas vesicle protein K DUF2012 PF09430.10 VBB32735.1 - 3.8e-31 107.8 0.0 5.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 VBB32735.1 - 0.0068 16.6 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SOP4 PF17081.5 VBB32735.1 - 0.051 13.1 0.4 0.64 9.5 0.1 2.4 2 1 1 3 3 3 0 Suppressor of PMA 1-7 protein CarbopepD_reg_2 PF13715.6 VBB32735.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Arf PF00025.21 VBB32736.1 - 7.8e-30 103.6 0.0 8.8e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 VBB32736.1 - 6.3e-10 38.7 0.2 0.00016 21.0 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 VBB32736.1 - 7.6e-08 32.4 0.0 9.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 VBB32736.1 - 1.4e-06 27.9 0.0 1.6e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 VBB32736.1 - 0.00013 22.2 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 VBB32736.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 VBB32736.1 - 0.0011 18.5 0.1 0.0017 17.9 0.1 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B 6PF2K PF01591.18 VBB32736.1 - 0.0071 15.7 0.1 0.035 13.4 0.1 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Ras PF00071.22 VBB32736.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.23 VBB32736.1 - 0.024 14.7 0.0 2.2 8.3 0.1 2.1 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 VBB32736.1 - 0.029 14.3 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 VBB32736.1 - 0.03 14.6 0.0 0.27 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain PK PF00224.21 VBB32737.1 - 1.3e-159 530.8 3.3 1.6e-159 530.4 3.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 VBB32737.1 - 2.4e-31 108.4 0.0 7.3e-31 106.8 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 VBB32737.1 - 0.0081 15.3 0.7 0.02 14.0 0.7 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AMPKBI PF04739.15 VBB32737.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain PK PF00224.21 VBB32738.1 - 6.6e-84 281.8 0.5 7.4e-84 281.6 0.5 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 VBB32738.1 - 7.4e-08 31.8 0.1 9.8e-08 31.4 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Metallophos PF00149.28 VBB32739.1 - 2.3e-41 142.5 0.0 3.2e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB32739.1 - 0.00013 22.3 0.7 0.00027 21.3 0.7 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glutaredoxin PF00462.24 VBB32740.1 - 5.6e-14 52.1 0.0 8.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin PP2C PF00481.21 VBB32741.1 - 1.9e-52 178.4 0.0 2.2e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C HMG_box PF00505.19 VBB32742.1 - 4.6e-15 55.8 1.7 6.9e-15 55.2 1.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB32742.1 - 7.9e-06 26.4 1.6 1.4e-05 25.6 1.6 1.4 1 0 0 1 1 1 1 HMG-box domain K_channel_TID PF07941.11 VBB32742.1 - 0.0029 18.0 13.3 0.0054 17.2 13.3 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain DUF4521 PF15021.6 VBB32742.1 - 0.063 13.2 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Ribosomal_60s PF00428.19 VBB32742.1 - 0.12 13.0 7.9 0.23 12.1 7.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Focal_AT PF03623.13 VBB32742.1 - 2.7 8.0 4.7 3.5 7.6 0.4 2.1 2 0 0 2 2 2 0 Focal adhesion targeting region Homeobox_KN PF05920.11 VBB32743.1 - 0.011 15.6 1.0 0.044 13.7 0.8 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF3439 PF11921.8 VBB32743.1 - 2.2 8.3 20.7 7.7 6.5 20.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3693 PF12472.8 VBB32743.1 - 3.6 7.3 4.9 22 4.8 0.1 2.5 2 0 0 2 2 2 0 Phage related protein DUF5401 PF17380.2 VBB32743.1 - 3.8 5.5 13.1 5.5 4.9 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PGA2 PF07543.12 VBB32743.1 - 5.7 6.9 8.0 0.86 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 zf-H2C2_2 PF13465.6 VBB32744.1 - 1.4e-05 25.2 4.4 0.0019 18.6 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB32744.1 - 0.075 13.5 0.7 0.075 13.5 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB32744.1 - 0.14 13.1 0.6 0.14 13.1 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SLC12 PF03522.15 VBB32744.1 - 4.1 6.3 17.0 6.7 5.6 17.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Utp14 PF04615.13 VBB32744.1 - 5.7 5.4 14.5 6.4 5.2 14.5 1.2 1 0 0 1 1 1 0 Utp14 protein Ub-Mut7C PF14451.6 VBB32745.1 - 0.064 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin MRC1 PF09444.10 VBB32745.1 - 0.26 11.8 8.4 0.33 11.4 7.7 1.5 1 1 0 1 1 1 0 MRC1-like domain TMF_DNA_bd PF12329.8 VBB32745.1 - 0.38 10.8 4.8 0.87 9.6 4.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GNAT_acetyltran PF12746.7 VBB32745.1 - 4.3 6.8 8.0 15 5.0 3.9 2.8 2 1 1 3 3 3 0 GNAT acetyltransferase DUF4175 PF13779.6 VBB32746.1 - 0.062 11.2 12.6 0.066 11.1 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Roughex PF06020.11 VBB32746.1 - 0.064 12.3 11.3 0.086 11.9 11.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Resistin PF06954.11 VBB32746.1 - 0.068 13.7 0.6 0.13 12.9 0.6 1.4 1 0 0 1 1 1 0 Resistin FAM199X PF15814.5 VBB32746.1 - 0.15 11.1 8.1 0.19 10.7 8.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X GREB1 PF15782.5 VBB32746.1 - 0.16 9.0 10.9 0.2 8.8 10.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CobT PF06213.12 VBB32746.1 - 1.1 8.6 15.5 1.6 8.1 15.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 VBB32746.1 - 1.6 8.8 16.4 0.73 10.0 13.6 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S64 PF08192.11 VBB32746.1 - 1.8 6.9 16.3 2.2 6.7 16.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.8 VBB32746.1 - 2.2 7.8 29.9 0.61 9.7 26.3 1.7 2 0 0 2 2 2 0 Spt20 family DUF4718 PF15842.5 VBB32746.1 - 2.3 8.0 13.4 0.41 10.4 8.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Pex26 PF07163.12 VBB32746.1 - 3.1 7.0 8.2 5.2 6.3 8.2 1.4 1 0 0 1 1 1 0 Pex26 protein DUF1180 PF06679.12 VBB32746.1 - 3.2 8.1 7.7 5.3 7.4 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Rrn6 PF10214.9 VBB32746.1 - 6.5 5.1 23.0 8.6 4.7 23.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ndc1_Nup PF09531.10 VBB32746.1 - 7 5.2 14.9 7 5.2 14.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AbLIM_anchor PF16182.5 VBB32746.1 - 8.4 6.1 19.1 1.5 8.6 14.3 1.7 1 1 1 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Zona_pellucida PF00100.23 VBB32747.1 - 2.4e-15 57.0 2.3 4.1e-15 56.3 2.3 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Septin PF00735.18 VBB32748.1 - 3.7e-52 177.4 0.1 6.9e-52 176.5 0.1 1.4 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 VBB32748.1 - 0.22 11.0 1.6 0.77 9.3 1.6 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF4011 PF13195.6 VBB32748.1 - 1.9 8.4 6.9 3.3 7.6 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) DZR PF12773.7 VBB32750.1 - 0.0088 16.1 10.0 0.04 14.0 1.9 2.4 2 0 0 2 2 2 2 Double zinc ribbon MAT1 PF06391.13 VBB32750.1 - 0.05 13.4 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 zinc_ribbon_2 PF13240.6 VBB32750.1 - 0.82 9.5 11.6 2 8.3 6.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 VBB32750.1 - 2.1 8.1 9.5 0.16 11.8 0.7 3.0 3 0 0 3 3 3 0 InsA N-terminal domain Exo_endo_phos PF03372.23 VBB32751.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hydrolase_4 PF12146.8 VBB32752.1 - 2.7e-13 49.7 0.0 3.4e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 VBB32752.1 - 4.3e-10 39.7 0.0 2.9e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 VBB32752.1 - 0.00011 21.8 0.0 0.00054 19.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 VBB32752.1 - 0.00017 21.0 0.7 0.21 10.9 0.2 2.1 1 1 0 2 2 2 2 Secretory lipase FSH1 PF03959.13 VBB32752.1 - 0.00033 20.4 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 VBB32752.1 - 0.00036 19.6 0.1 0.00053 19.0 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 VBB32752.1 - 0.00062 20.4 0.0 0.013 16.1 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 VBB32752.1 - 0.00082 19.2 0.0 0.0027 17.5 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 VBB32752.1 - 0.0039 16.8 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 VBB32752.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC2_membrane_2 PF12679.7 VBB32754.1 - 4 6.6 4.4 7.5 5.7 4.4 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Oxidored_FMN PF00724.20 VBB32755.1 - 4.8e-21 75.4 0.0 4.9e-20 72.1 0.0 2.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UDPG_MGDP_dh_N PF03721.14 VBB32755.1 - 0.091 12.3 2.9 0.2 11.2 2.9 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BAP PF06639.11 VBB32755.1 - 0.16 12.3 0.7 0.58 10.5 0.7 1.9 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) TipAS PF07739.13 VBB32755.1 - 1.4 9.5 4.8 4.7 7.8 0.8 3.4 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain T4_Rnl2_C PF18043.1 VBB32755.1 - 5.9 7.1 7.2 4 7.6 1.5 3.7 2 1 1 3 3 3 0 T4 RNA ligase 2 C-terminal SH3BP5 PF05276.14 VBB32756.1 - 4.3e-74 249.2 22.2 9.1e-74 248.1 22.2 1.6 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF1664 PF07889.12 VBB32756.1 - 3.9 7.5 10.2 0.12 12.4 1.2 3.0 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Acetyltransf_1 PF00583.25 VBB32757.1 - 2.5e-10 40.6 0.1 3.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 VBB32757.1 - 2.2e-07 31.2 0.2 3.8e-07 30.4 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 VBB32757.1 - 3.8e-06 26.8 0.0 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 VBB32757.1 - 5.3e-06 26.4 0.2 8.9e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 VBB32757.1 - 6.2e-05 23.1 0.2 0.00023 21.2 0.1 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain TPR_15 PF13429.6 VBB32757.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 VBB32759.1 - 1.5e-20 73.3 11.3 3.4e-20 72.1 11.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 VBB32759.1 - 6.6e-16 58.2 7.7 1.6e-15 56.9 7.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 VBB32759.1 - 0.0075 16.0 2.0 0.0075 16.0 2.0 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 VBB32759.1 - 0.048 14.0 17.4 0.066 13.5 12.6 2.9 2 1 0 2 2 2 0 Ring finger domain HemY_N PF07219.13 VBB32759.1 - 0.073 13.3 0.4 0.22 11.7 0.4 1.8 1 0 0 1 1 1 0 HemY protein N-terminus zf-C3HC4_2 PF13923.6 VBB32759.1 - 2.2 8.2 13.2 78 3.2 13.2 2.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB32759.1 - 4.9 7.1 15.9 1.3 9.0 10.2 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 VBB32759.1 - 8.7 6.6 12.4 1.8 8.8 8.0 2.2 2 1 1 3 3 3 0 FANCL C-terminal domain Arm_vescicular PF18770.1 VBB32760.1 - 0.03 14.2 0.2 0.29 11.1 0.1 2.5 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor PSD4 PF07631.11 VBB32760.1 - 0.99 10.0 14.4 0.41 11.2 2.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) HBS1_N PF08938.10 VBB32760.1 - 8.4 6.8 9.7 1.2 9.5 1.3 3.9 2 1 1 3 3 3 0 HBS1 N-terminus Peptidase_S9 PF00326.21 VBB32761.1 - 5.6e-60 202.4 0.0 6.7e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 VBB32761.1 - 0.093 12.6 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9_N PF02897.15 VBB32761.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pkinase PF00069.25 VBB32763.1 - 1.1e-23 84.0 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32763.1 - 2e-10 40.4 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB32763.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Neur_chan_LBD PF02931.23 VBB32764.1 - 2.5e-40 138.2 1.4 4.2e-40 137.5 1.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB32764.1 - 4.1e-27 95.8 4.2 2.6e-23 83.3 0.4 2.8 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region D123 PF07065.14 VBB32764.1 - 0.028 13.6 0.1 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 D123 Ribosomal_L26 PF16906.5 VBB32765.1 - 5e-39 132.6 3.5 7.6e-39 132.0 3.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 VBB32765.1 - 4.3e-06 26.5 2.1 4.3e-06 26.5 2.1 2.2 3 0 0 3 3 3 1 KOW motif Phage_portal PF04860.12 VBB32765.1 - 0.095 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein KIP1 PF07765.12 VBB32766.1 - 0.06 13.5 0.8 0.33 11.1 0.8 2.3 1 0 0 1 1 1 0 KIP1-like protein Glyco_tran_10_N PF17039.5 VBB32766.1 - 0.52 10.8 2.1 49 4.4 0.1 3.2 3 0 0 3 3 3 0 Fucosyltransferase, N-terminal PIN_9 PF18477.1 VBB32766.1 - 2.9 8.2 5.9 1.6 9.1 0.1 3.3 2 1 1 3 3 3 0 PIN like domain TMPIT PF07851.13 VBB32766.1 - 3.4 6.8 8.8 6.8 5.8 8.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF3395 PF11875.8 VBB32768.1 - 0.0082 16.0 1.5 0.0094 15.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) FoP_duplication PF13865.6 VBB32768.1 - 0.013 16.0 0.0 0.013 16.0 0.0 2.7 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Cation_ATPase_C PF00689.21 VBB32769.1 - 4.6e-33 114.5 2.5 7.1e-33 113.8 2.5 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 VBB32769.1 - 2.1e-13 51.0 0.1 9.8e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 VBB32769.1 - 6.1e-13 48.7 0.1 1.2e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 VBB32769.1 - 0.00078 19.3 0.6 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Rhodanese PF00581.20 VBB32770.1 - 1.4e-18 67.4 0.4 1.1e-08 35.5 0.1 2.5 2 0 0 2 2 2 2 Rhodanese-like domain LRR_8 PF13855.6 VBB32771.1 - 8e-29 99.2 51.4 8.8e-09 35.0 6.8 8.3 7 2 2 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 VBB32771.1 - 8.8e-20 70.5 54.2 1.1e-07 32.0 2.6 9.8 7 1 4 11 11 11 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB32771.1 - 1.1e-05 25.0 14.5 0.0036 16.8 1.3 4.5 2 1 1 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.6 VBB32771.1 - 0.0023 17.9 6.6 0.25 11.3 0.2 3.3 3 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 VBB32771.1 - 0.038 14.5 63.5 0.35 11.6 0.5 14.6 14 3 1 15 15 15 0 Leucine Rich Repeat Ribosomal_L19 PF01245.20 VBB32772.1 - 2e-16 59.9 1.3 3.4e-16 59.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L19 PA28_beta PF02252.18 VBB32772.1 - 0.086 12.5 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit TRC8_N PF13705.6 VBB32773.1 - 5.2e-76 256.6 38.7 6.1e-76 256.3 38.7 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 VBB32773.1 - 1.7e-09 37.9 8.6 4.8e-09 36.4 8.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB32773.1 - 3.6e-09 36.3 9.0 1.1e-08 34.8 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB32773.1 - 2.7e-08 33.6 8.4 6.5e-08 32.3 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB32773.1 - 1.4e-06 28.5 9.9 5.6e-06 26.6 9.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 VBB32773.1 - 1.1e-05 25.0 2.8 1.1e-05 25.0 2.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 VBB32773.1 - 0.00073 19.4 7.3 0.0018 18.2 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB32773.1 - 0.0008 19.4 4.2 0.00096 19.1 2.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 VBB32773.1 - 0.0075 16.3 3.8 0.019 15.0 3.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 VBB32773.1 - 0.031 14.1 9.7 0.075 12.9 9.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 VBB32773.1 - 0.096 12.6 4.7 0.26 11.2 4.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 VBB32773.1 - 0.81 9.6 10.7 1.8 8.5 10.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 VBB32773.1 - 2.4 7.8 10.0 1.3 8.7 7.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF2045 PF09741.9 VBB32774.1 - 1.2e-86 289.9 0.2 2e-86 289.2 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) HCO3_cotransp PF00955.21 VBB32775.1 - 4.3e-95 319.5 8.1 5.9e-95 319.0 8.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 VBB32775.1 - 4.8e-93 311.8 0.3 9.4e-93 310.9 0.0 1.6 2 0 0 2 2 2 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 VBB32775.1 - 0.0087 16.0 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 BTB PF00651.31 VBB32776.1 - 0.0002 21.5 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 VBB32776.1 - 0.00033 21.0 24.8 0.021 15.3 1.9 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 VBB32776.1 - 0.00039 20.1 12.3 0.0025 17.5 1.8 3.0 3 0 0 3 3 3 2 C2H2-type zinc-finger domain SLY PF12485.8 VBB32776.1 - 0.035 14.8 2.9 0.11 13.3 0.3 2.3 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein zf-Di19 PF05605.12 VBB32776.1 - 0.058 13.7 4.5 2.1 8.7 0.1 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3490 PF11995.8 VBB32776.1 - 0.064 13.1 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) RNA_POL_M_15KD PF02150.16 VBB32776.1 - 0.11 12.3 5.0 2.5 8.1 0.1 2.9 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_4 PF13894.6 VBB32776.1 - 0.26 12.2 26.6 0.75 10.8 1.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 VBB32776.1 - 0.47 10.1 7.3 0.48 10.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 VBB32776.1 - 0.54 10.6 12.9 0.23 11.8 1.2 3.3 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Seryl_tRNA_N PF02403.22 VBB32776.1 - 1.9 8.7 5.2 0.36 11.1 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glyco_transf_11 PF01531.16 VBB32778.1 - 3.4e-24 85.6 5.8 3.6e-24 85.5 5.8 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 11 CsgA PF17334.2 VBB32778.1 - 0.0045 17.7 0.9 0.024 15.4 0.5 2.3 2 1 0 2 2 2 1 Minor curli fiber component A An_peroxidase PF03098.15 VBB32779.1 - 1e-21 77.1 0.6 1.3e-21 76.9 0.0 1.4 2 0 0 2 2 2 1 Animal haem peroxidase VWC PF00093.18 VBB32779.1 - 0.006 16.9 3.5 0.018 15.3 3.5 1.9 1 1 0 1 1 1 1 von Willebrand factor type C domain ORC5_C PF14630.6 VBB32783.1 - 1.2e-37 129.9 0.0 1.5e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus TPR_MLP1_2 PF07926.12 VBB32784.1 - 3.2e-05 24.0 59.8 0.00051 20.1 7.0 5.1 3 2 1 4 4 4 3 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 VBB32784.1 - 0.0044 16.8 2.1 0.0044 16.8 2.1 6.6 5 2 2 7 7 7 2 GIT coiled-coil Rho guanine nucleotide exchange factor ERM PF00769.19 VBB32784.1 - 0.012 15.4 60.6 0.4 10.5 18.2 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 VBB32784.1 - 0.013 15.5 24.9 0.013 15.5 24.9 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.12 VBB32784.1 - 0.07 13.4 0.6 0.07 13.4 0.6 4.3 3 2 1 5 5 5 0 Proteins of 100 residues with WXG Halo_GVPC PF05465.13 VBB32784.1 - 0.21 11.9 0.3 0.21 11.9 0.3 3.6 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat Zw10 PF06248.13 VBB32784.1 - 0.25 9.9 25.7 0.0065 15.1 15.4 2.2 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 KASH_CCD PF14662.6 VBB32784.1 - 0.29 11.0 66.8 0.16 11.7 24.6 4.5 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 VBB32784.1 - 0.36 10.1 63.9 0.26 10.6 4.3 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 VBB32784.1 - 0.58 9.6 63.6 0.32 10.4 20.4 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 PspA_IM30 PF04012.12 VBB32784.1 - 1.3 8.5 44.0 3.4 7.2 2.9 3.6 2 2 1 3 3 3 0 PspA/IM30 family Lebercilin PF15619.6 VBB32784.1 - 1.6 8.4 66.4 3.5 7.2 24.1 4.1 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Leu_zip PF15294.6 VBB32784.1 - 3 7.3 56.2 0.87 9.0 18.4 3.4 1 1 1 3 3 3 0 Leucine zipper UPF0242 PF06785.11 VBB32784.1 - 7.7 6.6 64.8 0.56 10.3 6.5 3.9 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 VBB32784.1 - 9.1 6.8 40.7 9 6.8 2.3 6.9 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) TPR_2 PF07719.17 VBB32787.1 - 5.2e-13 48.0 9.7 0.034 14.3 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32787.1 - 1.4e-10 41.5 12.0 0.056 14.0 0.2 5.6 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB32787.1 - 3.2e-08 33.7 11.8 0.0012 19.5 0.4 5.7 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB32787.1 - 7.6e-08 32.9 7.0 0.035 14.8 0.1 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB32787.1 - 2.1e-06 27.3 13.1 0.14 12.1 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB32787.1 - 6e-06 26.4 22.3 0.0098 16.1 2.9 4.7 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 VBB32787.1 - 9e-06 25.5 4.6 0.4 11.0 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB32787.1 - 3e-05 23.6 1.2 0.0032 17.1 0.1 4.2 5 0 0 5 5 5 1 TPR repeat TPR_21 PF09976.9 VBB32787.1 - 0.00052 19.8 9.3 0.012 15.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain ELYS PF13934.6 VBB32787.1 - 0.0013 18.8 6.9 0.048 13.6 1.8 3.6 2 2 2 4 4 4 1 Nuclear pore complex assembly TPR_15 PF13429.6 VBB32787.1 - 0.0019 17.4 16.0 0.044 13.0 2.9 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB32787.1 - 0.003 17.8 13.6 10 6.5 0.0 6.6 5 3 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 VBB32787.1 - 0.017 15.0 5.5 6.2 6.8 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TED_complement PF07678.14 VBB32787.1 - 0.032 13.2 2.3 0.5 9.3 0.5 2.6 1 1 1 2 2 2 0 A-macroglobulin TED domain TPR_17 PF13431.6 VBB32787.1 - 0.039 14.3 0.5 1.2e+02 3.4 0.0 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 VBB32787.1 - 0.14 11.8 7.8 1.3 8.6 0.6 3.3 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) CRISPR_Cse2 PF09485.10 VBB32787.1 - 0.15 12.6 4.5 2 8.9 0.7 2.9 2 1 1 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_6 PF13174.6 VBB32787.1 - 0.88 10.3 7.9 90 4.0 0.1 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 VBB32787.1 - 1.7 8.8 13.4 16 5.8 0.1 6.1 7 1 0 7 7 6 0 Tetratricopeptide repeat Rib_5-P_isom_A PF06026.14 VBB32788.1 - 4.7e-61 205.4 0.0 5.7e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 VBB32788.1 - 0.01 15.8 0.1 0.24 11.3 0.0 2.2 1 1 0 2 2 2 0 DeoR C terminal sensor domain BpuJI_N PF11564.8 VBB32788.1 - 0.089 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal Sugar-bind PF04198.13 VBB32788.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DUF2290 PF10053.9 VBB32788.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) OST3_OST6 PF04756.13 VBB32789.1 - 0.011 15.0 0.5 0.018 14.4 0.5 1.4 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family MFS_1 PF07690.16 VBB32790.1 - 2e-12 46.7 18.5 6.3e-10 38.5 20.3 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 VBB32790.1 - 6.5e-10 38.8 9.9 9.3e-10 38.3 9.9 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Ank_2 PF12796.7 VBB32792.1 - 1.5e-58 195.4 25.6 2.4e-13 50.5 1.1 4.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB32792.1 - 2.5e-39 128.8 11.7 0.00019 21.6 0.0 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 VBB32792.1 - 7.4e-38 127.4 19.4 3.7e-06 27.1 0.2 7.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 VBB32792.1 - 1.1e-37 127.9 9.0 7e-11 42.4 0.0 6.1 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB32792.1 - 2.7e-35 120.0 20.6 3.6e-08 33.5 0.1 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) CX PF01705.19 VBB32793.1 - 3.8e-09 36.9 3.8 7e-09 36.1 3.8 1.5 1 0 0 1 1 1 1 CX module DUF2076 PF09849.9 VBB32793.1 - 0.011 15.8 8.9 0.016 15.3 8.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 VBB32793.1 - 0.023 15.4 0.7 0.031 15.0 0.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region C2 PF00168.30 VBB32794.1 - 1e-51 173.5 0.1 2.1e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 VBB32794.1 - 2.4e-05 24.3 0.1 0.011 15.6 0.0 2.6 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 PTEN_C2 PF10409.9 VBB32794.1 - 0.014 15.1 1.0 1.7 8.4 0.0 3.0 2 1 1 3 3 3 0 C2 domain of PTEN tumour-suppressor protein CEP76-C2 PF15627.6 VBB32794.1 - 0.021 14.4 0.1 3.2 7.3 0.0 2.4 2 1 0 2 2 2 0 CEP76 C2 domain Carb_anhydrase PF00194.21 VBB32795.1 - 6.2e-53 179.9 0.0 8.1e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Wtap PF17098.5 VBB32796.1 - 1e-24 87.2 13.4 1e-24 87.2 13.4 2.3 2 1 0 2 2 2 1 WTAP/Mum2p family ADIP PF11559.8 VBB32796.1 - 0.011 15.8 6.0 0.011 15.8 6.0 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding zf_C2H2_ZHX PF18387.1 VBB32796.1 - 0.05 13.2 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain bZIP_2 PF07716.15 VBB32797.1 - 3.5e-10 39.8 16.4 4.6e-10 39.4 16.4 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 VBB32797.1 - 1.4e-05 25.0 11.5 2e-05 24.6 11.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor GBR2_CC PF18455.1 VBB32797.1 - 0.017 15.3 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF5320 PF17253.2 VBB32797.1 - 0.055 14.5 0.7 0.073 14.1 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) bZIP_Maf PF03131.17 VBB32797.1 - 0.066 13.7 8.1 0.086 13.4 8.1 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor Nup54_57_C PF18570.1 VBB32797.1 - 0.11 12.2 1.8 0.17 11.5 0.8 1.9 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain APG6_N PF17675.1 VBB32797.1 - 0.2 12.2 3.5 0.24 11.9 3.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region MAS20 PF02064.15 VBB32798.1 - 6.9e-40 136.1 0.9 2.2e-39 134.5 0.9 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor Tmemb_55A PF09788.9 VBB32799.1 - 2.5e-09 36.6 3.2 4.1e-09 35.9 3.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 55A zf-H2C2_2 PF13465.6 VBB32799.1 - 0.0094 16.3 1.9 2.3 8.8 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger double domain A2L_zn_ribbon PF08792.10 VBB32799.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain zinc_ribbon_9 PF14369.6 VBB32799.1 - 0.012 15.9 1.5 0.54 10.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-TFIIB PF13453.6 VBB32799.1 - 0.044 13.1 0.2 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_Tnp_IS1595 PF12760.7 VBB32799.1 - 0.11 12.5 5.2 1.2 9.1 0.8 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Phage_holin_3_6 PF07332.11 VBB32799.1 - 0.15 12.1 2.9 0.19 11.8 2.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1451 PF07295.11 VBB32799.1 - 0.15 12.1 0.1 0.22 11.6 0.1 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-LSD1 PF06943.12 VBB32799.1 - 0.19 11.6 2.1 0.44 10.4 2.1 1.7 1 0 0 1 1 1 0 LSD1 zinc finger Ribosomal_L37ae PF01780.19 VBB32799.1 - 0.25 11.4 0.4 0.4 10.8 0.4 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family TF_Zn_Ribbon PF08271.12 VBB32799.1 - 0.4 10.2 3.1 9.1 5.9 3.8 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding DUF5641 PF18701.1 VBB32800.1 - 9.8e-11 41.7 0.2 1.7e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) NUMOD4 PF07463.11 VBB32800.1 - 0.025 14.7 0.1 0.055 13.7 0.1 1.6 1 0 0 1 1 1 0 NUMOD4 motif Pribosyl_synth PF14572.6 VBB32801.1 - 1.7e-89 298.7 0.2 3e-89 297.9 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 VBB32801.1 - 5e-38 129.6 0.5 5e-38 129.6 0.5 1.6 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 VBB32801.1 - 8.8e-06 25.3 0.2 2.9e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 Phosphoribosyl transferase domain DAHP_synth_2 PF01474.16 VBB32801.1 - 0.13 10.8 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Class-II DAHP synthetase family PEX-2N PF09263.10 VBB32801.1 - 0.21 11.9 0.2 0.82 10.0 0.0 2.0 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Thioredoxin PF00085.20 VBB32803.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin SHR3_chaperone PF08229.11 VBB32803.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 DnaJ PF00226.31 VBB32804.1 - 1e-23 83.2 0.5 4e-23 81.3 0.5 2.1 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 VBB32804.1 - 1.9e-08 34.4 9.2 1.9e-08 34.4 9.2 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 VBB32804.1 - 8.5e-05 22.8 3.9 8.5e-05 22.8 3.9 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 VBB32804.1 - 0.00014 22.1 8.2 0.11 12.8 5.2 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 VBB32804.1 - 0.00056 20.5 10.0 0.036 14.9 1.0 3.8 4 0 0 4 4 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB32804.1 - 0.0014 19.0 10.6 0.2 12.1 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type RPT PF13446.6 VBB32804.1 - 0.011 15.7 0.0 0.4 10.7 0.1 3.4 3 1 1 4 4 4 0 A repeated domain in UCH-protein DUF4187 PF13821.6 VBB32804.1 - 0.031 14.1 0.6 0.031 14.1 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Phage_X PF05155.15 VBB32804.1 - 0.086 13.3 0.0 0.51 10.8 0.0 2.5 2 0 0 2 2 2 0 Phage X family zf-C2H2_6 PF13912.6 VBB32804.1 - 0.2 11.7 10.3 1.6 8.8 4.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Ripply PF14998.6 VBB32804.1 - 0.27 11.9 2.4 0.91 10.2 0.0 3.1 2 1 0 2 2 2 0 Transcription Regulator LIM PF00412.22 VBB32804.1 - 0.45 10.8 4.1 1.1 9.5 1.4 2.7 2 0 0 2 2 2 0 LIM domain DUF4718 PF15842.5 VBB32804.1 - 0.69 9.7 6.7 0.7 9.7 4.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4718) SPATA3 PF15662.5 VBB32804.1 - 2.8 8.5 5.5 6.4 7.4 5.5 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family F-box-like PF12937.7 VBB32806.1 - 1.5e-09 37.6 0.6 3.4e-09 36.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB32806.1 - 3.1e-07 30.1 0.0 8.2e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ribosomal_S2 PF00318.20 VBB32806.1 - 0.0059 15.9 1.6 0.012 14.9 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S2 TetR_C_30 PF17939.1 VBB32806.1 - 0.017 15.4 0.2 0.035 14.3 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Metalloenzyme PF01676.18 VBB32807.1 - 1.3e-77 260.5 0.2 1.5e-77 260.3 0.2 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 VBB32807.1 - 8.2e-74 247.7 0.2 1.3e-73 247.1 0.2 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 VBB32807.1 - 5.4e-06 26.2 0.0 9.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 VBB32807.1 - 0.00013 21.4 0.0 0.00079 18.9 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 VBB32807.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Alkaline phosphatase PglZ PF08665.12 VBB32807.1 - 0.11 12.6 0.0 0.93 9.6 0.0 2.1 2 0 0 2 2 2 0 PglZ domain Collagen PF01391.18 VBB32808.1 - 1.4e-26 92.0 96.2 9.9e-11 41.2 35.7 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB32808.1 - 0.0042 17.1 0.0 0.0057 16.7 0.0 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain DNA_repr_REX1B PF14966.6 VBB32811.1 - 2.6e-05 24.8 0.8 8.2e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 DNA repair REX1-B BBS2_C PF14782.6 VBB32811.1 - 0.0049 15.7 0.8 0.0066 15.3 0.8 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal DUF4407 PF14362.6 VBB32811.1 - 0.0082 15.5 3.8 0.014 14.7 3.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 VBB32811.1 - 0.018 15.1 3.6 0.024 14.7 1.5 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 VBB32811.1 - 0.021 14.7 4.2 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Med11 PF10280.9 VBB32811.1 - 0.027 14.9 1.0 0.074 13.5 1.0 1.9 1 1 0 1 1 1 0 Mediator complex protein MHB PF16525.5 VBB32811.1 - 0.029 14.6 0.5 0.13 12.5 0.0 2.3 2 2 1 3 3 3 0 Haemophore, haem-binding Phage_min_cap2 PF06152.11 VBB32811.1 - 0.031 13.2 4.6 0.038 12.9 4.6 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 Snapin_Pallidin PF14712.6 VBB32811.1 - 0.053 14.0 4.2 4 7.9 0.2 2.7 1 1 2 3 3 3 0 Snapin/Pallidin DASH_Duo1 PF08651.10 VBB32811.1 - 0.055 13.2 1.2 0.33 10.7 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 BAR_3 PF16746.5 VBB32811.1 - 0.073 12.8 5.1 0.12 12.0 5.1 1.5 1 1 0 1 1 1 0 BAR domain of APPL family DUF1664 PF07889.12 VBB32811.1 - 0.11 12.5 1.9 0.3 11.1 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) KELK PF15796.5 VBB32811.1 - 0.13 12.8 2.8 0.38 11.2 0.6 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FlaC_arch PF05377.11 VBB32811.1 - 0.18 12.2 3.0 4.8 7.6 0.7 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.6 VBB32811.1 - 0.27 11.6 6.3 1 9.8 3.7 2.2 1 1 1 2 2 2 0 Syntaxin-like protein CREPT PF16566.5 VBB32811.1 - 0.35 11.0 3.3 0.28 11.3 0.6 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SDF PF00375.18 VBB32812.1 - 2.8e-122 408.5 39.3 3.4e-122 408.2 39.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2457 PF10446.9 VBB32814.1 - 0.75 8.9 35.7 0.9 8.6 35.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 VBB32814.1 - 0.96 7.5 33.9 1.1 7.3 33.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 VBB32814.1 - 3.6 5.7 20.7 4 5.6 20.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 VBB32814.1 - 7 5.0 19.8 7.4 4.9 19.8 1.0 1 0 0 1 1 1 0 Mpp10 protein Ribosom_S12_S23 PF00164.25 VBB32815.1 - 1e-47 160.4 0.3 1.6e-47 159.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Pkinase PF00069.25 VBB32816.1 - 8.9e-59 199.0 0.0 1.5e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32816.1 - 2.3e-25 89.4 0.0 4.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32816.1 - 5.8e-07 29.1 0.0 9.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB32816.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB32816.1 - 0.00028 19.8 0.0 0.00078 18.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 VBB32816.1 - 0.0017 18.0 0.1 0.0052 16.4 0.1 1.8 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 VBB32816.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 VBB32816.1 - 0.093 12.3 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 UPF0172 PF03665.13 VBB32816.1 - 0.14 12.2 1.0 0.49 10.4 1.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) LUC7 PF03194.15 VBB32817.1 - 2.8e-55 187.7 12.9 2.8e-55 187.7 12.9 1.5 2 0 0 2 2 2 1 LUC7 N_terminus Cytochrom_B562 PF07361.11 VBB32817.1 - 1.5 9.5 5.9 18 6.0 0.1 3.4 3 1 0 4 4 4 0 Cytochrome b562 NPV_P10 PF05531.12 VBB32818.1 - 0.00078 19.9 1.2 0.0032 17.9 0.1 2.4 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 VBB32818.1 - 0.029 14.4 2.2 0.029 14.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 VBB32818.1 - 0.041 14.2 1.0 0.19 12.1 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 VBB32818.1 - 0.09 12.8 1.3 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myelin_PLP PF01275.19 VBB32819.1 - 6.8e-28 98.1 17.4 4e-20 72.7 9.0 2.0 1 1 1 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) Abhydrolase_9_N PF15420.6 VBB32819.1 - 0.12 12.4 8.5 0.087 12.8 6.8 1.6 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Tmemb_cc2 PF10267.9 VBB32819.1 - 0.51 9.4 0.7 0.73 8.9 0.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein LapA_dom PF06305.11 VBB32819.1 - 0.56 10.1 5.0 15 5.5 0.1 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF373 PF04123.13 VBB32819.1 - 1.4 8.3 6.2 1.9 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Saf_2TM PF18303.1 VBB32819.1 - 6.5 6.3 7.2 2.5 7.7 3.5 2.2 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Astacin PF01400.24 VBB32820.1 - 2e-45 154.8 0.1 3.1e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 VBB32820.1 - 4.3e-06 27.0 0.4 1.1e-05 25.7 0.1 1.8 2 0 0 2 2 2 1 CUB domain Peptidase_M10 PF00413.24 VBB32820.1 - 9.2e-05 22.3 0.1 0.023 14.6 0.0 2.3 2 0 0 2 2 2 2 Matrixin Reprolysin_5 PF13688.6 VBB32820.1 - 0.0084 16.3 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 VBB32820.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 VBB32820.1 - 0.061 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 VBB32820.1 - 0.078 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 VBB32820.1 - 0.13 12.8 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 VBB32820.1 - 0.13 11.5 0.3 0.2 10.8 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Motile_Sperm PF00635.26 VBB32821.1 - 9.8e-26 89.7 0.0 1.1e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Rab5-bind PF09311.11 VBB32823.1 - 3.9e-62 210.4 41.6 6.5e-62 209.7 41.6 1.4 1 0 0 1 1 1 1 Rabaptin-like protein FYVE PF01363.21 VBB32823.1 - 2.6e-12 46.7 10.2 2.6e-12 46.7 10.2 2.5 2 1 0 2 2 2 1 FYVE zinc finger Med9 PF07544.13 VBB32823.1 - 0.0028 17.7 1.2 0.0028 17.7 1.2 4.2 3 1 2 5 5 5 1 RNA polymerase II transcription mediator complex subunit 9 HTH_Tnp_Tc3_1 PF11427.8 VBB32823.1 - 0.02 14.7 0.1 0.073 12.9 0.1 1.9 1 0 0 1 1 1 0 Tc3 transposase IBR PF01485.21 VBB32823.1 - 0.23 11.7 9.5 0.059 13.6 4.6 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CREPT PF16566.5 VBB32823.1 - 1.1 9.4 31.4 0.035 14.3 4.3 3.8 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour FUSC PF04632.12 VBB32823.1 - 3.2 6.2 8.4 4 5.8 7.5 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family 4F5 PF04419.14 VBB32824.1 - 4.3e-10 40.3 7.8 6.6e-10 39.7 7.8 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 VBB32824.1 - 0.032 14.6 0.5 0.063 13.7 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-met2 PF12907.7 VBB32824.1 - 0.75 10.0 5.8 6.5 7.0 5.8 2.2 1 1 0 1 1 1 0 Zinc-binding Ribosomal_L12 PF00542.19 VBB32825.1 - 1e-20 73.8 4.6 2.1e-20 72.8 4.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 VBB32825.1 - 3.7e-05 23.3 3.4 8.8e-05 22.1 0.0 2.7 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DUF4479 PF14794.6 VBB32825.1 - 0.05 13.5 0.6 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) MRP-S27 PF10037.9 VBB32825.1 - 0.076 11.9 0.7 0.11 11.3 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Bromodomain PF00439.25 VBB32826.1 - 7.1e-23 80.5 0.3 1.7e-22 79.3 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Cullin PF00888.22 VBB32826.1 - 0.0011 17.6 0.2 0.0016 17.1 0.2 1.1 1 0 0 1 1 1 1 Cullin family LapA_dom PF06305.11 VBB32827.1 - 0.015 15.1 1.2 0.034 14.0 1.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DHHC PF01529.20 VBB32827.1 - 0.098 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_S9 PF00380.19 VBB32828.1 - 2.5e-20 73.2 0.0 6.1e-20 72.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 RGS PF00615.19 VBB32829.1 - 1e-23 83.8 0.3 1.7e-23 83.1 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ig_3 PF13927.6 VBB32830.1 - 1.3e-21 77.0 0.0 6.4e-11 42.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 VBB32830.1 - 8.4e-20 70.6 0.1 1.4e-10 41.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 VBB32830.1 - 6.1e-19 68.0 0.0 7.8e-10 38.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 VBB32830.1 - 4.9e-18 65.3 0.0 1.9e-07 31.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 VBB32830.1 - 2.6e-08 34.2 0.0 0.012 16.0 0.0 3.3 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 VBB32830.1 - 2.6e-07 30.8 0.8 0.091 13.0 0.0 3.6 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 VBB32830.1 - 0.00099 19.3 0.7 4.8 7.4 0.0 3.8 3 1 1 4 4 4 1 Immunoglobulin V-set domain Ig_6 PF18452.1 VBB32830.1 - 0.0021 17.6 0.0 2.4 7.8 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 VBB32830.1 - 0.011 15.8 0.0 0.48 10.5 0.0 2.9 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain NAGidase PF07555.13 VBB32830.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Laminin_G_2 PF02210.24 VBB32831.1 - 1.2e-25 90.6 0.0 3.6e-15 56.7 0.0 2.6 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.23 VBB32831.1 - 4.1e-23 82.0 0.0 4.8e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Ig_3 PF13927.6 VBB32831.1 - 8.1e-08 32.8 0.0 2.8e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Laminin_G_3 PF13385.6 VBB32831.1 - 1e-06 28.9 0.0 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Ig_2 PF13895.6 VBB32831.1 - 2.1e-06 28.0 1.0 4.1e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 VBB32831.1 - 3.2e-05 23.9 0.0 8.7e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 VBB32831.1 - 0.00066 19.8 0.2 0.12 12.5 0.1 3.3 2 1 1 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 VBB32831.1 - 0.0033 17.6 0.0 0.0093 16.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain EGF PF00008.27 VBB32831.1 - 0.018 15.4 14.3 0.38 11.1 2.1 2.5 1 1 1 2 2 2 0 EGF-like domain Vps26 PF03643.15 VBB32831.1 - 0.053 12.5 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Peptidase_M14 PF00246.24 VBB32832.1 - 3.5e-85 286.3 0.0 4e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase SBP_bac_6 PF13343.6 VBB32832.1 - 0.0046 16.4 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Ank_2 PF12796.7 VBB32833.1 - 3.2e-131 428.2 31.4 7.7e-16 58.5 3.5 11.2 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 VBB32833.1 - 7.2e-116 374.1 55.1 2.6e-08 33.9 0.1 21.3 20 1 1 21 21 21 19 Ankyrin repeat Ank_4 PF13637.6 VBB32833.1 - 1.1e-107 351.1 47.3 9.2e-12 45.2 0.4 14.2 6 5 10 16 16 16 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB32833.1 - 1.8e-104 340.4 40.4 1.9e-13 50.3 0.0 16.0 3 3 15 18 18 18 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB32833.1 - 8.4e-104 326.9 29.2 1.9e-06 27.7 0.0 21.1 21 0 0 21 21 21 17 Ankyrin repeat ZU5 PF00791.20 VBB32833.1 - 1.2e-35 121.8 0.8 4.6e-29 100.6 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain UPA_2 PF17809.1 VBB32833.1 - 1.6e-26 92.7 0.0 4e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 UPA domain DAG1 PF05454.11 VBB32833.1 - 0.1 12.0 0.3 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 VBB32833.1 - 0.13 12.2 0.7 0.26 11.2 0.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family PK_C PF02887.16 VBB32833.1 - 0.3 11.3 2.2 2.8 8.2 0.1 3.7 4 1 0 4 4 4 0 Pyruvate kinase, alpha/beta domain Imm_superinfect PF14373.6 VBB32833.1 - 9.8 6.2 5.7 1.3e+02 2.6 0.0 5.6 8 0 0 8 8 8 0 Superinfection immunity protein TMEM51 PF15345.6 VBB32834.1 - 0.43 10.4 7.4 1.2 8.9 7.4 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 RLI PF04068.15 VBB32837.1 - 0.43 10.4 4.3 3 7.7 1.6 2.4 2 0 0 2 2 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI Peptidase_A17 PF05380.13 VBB32838.1 - 6.2e-23 81.6 0.3 2.1e-22 79.9 0.1 2.0 2 0 0 2 2 2 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 VBB32838.1 - 0.0065 16.6 0.6 0.018 15.1 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain HTH_16 PF12645.7 VBB32838.1 - 0.063 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain BBIP10 PF14777.6 VBB32838.1 - 0.064 12.8 0.1 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 ERAP1_C PF11838.8 VBB32839.1 - 4.4e-06 26.5 0.0 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Inhibitor_I29 PF08246.12 VBB32839.1 - 0.11 13.0 1.9 24 5.5 0.3 3.0 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) Ly-6_related PF06579.12 VBB32840.1 - 9.4e-38 129.3 2.9 1.3e-37 128.8 2.9 1.2 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein QVR PF17064.5 VBB32840.1 - 1 9.6 8.7 22 5.4 8.7 2.8 1 1 0 1 1 1 0 Sleepless protein TGF_beta PF00019.20 VBB32843.1 - 4e-31 108.1 0.5 1.1e-30 106.7 0.5 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain RecQ_Zn_bind PF16124.5 VBB32843.1 - 0.045 14.5 0.7 0.31 11.8 0.4 2.3 2 0 0 2 2 2 0 RecQ zinc-binding Glyco_hydro_47 PF01532.20 VBB32844.1 - 3.5e-48 164.6 0.0 2.9e-47 161.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Zip PF02535.22 VBB32844.1 - 1.1e-35 123.4 0.2 1.8e-35 122.8 0.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter zf-CSL PF05207.13 VBB32845.1 - 3.1e-19 68.4 2.7 4.7e-19 67.9 2.7 1.3 1 0 0 1 1 1 1 CSL zinc finger Pkinase PF00069.25 VBB32846.1 - 9.7e-54 182.5 0.0 1.2e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32846.1 - 1.5e-40 139.2 0.0 1.9e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB32846.1 - 9.2e-06 25.2 0.0 3.2e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 VBB32846.1 - 0.00041 19.2 0.0 0.0014 17.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB32846.1 - 0.0012 18.0 0.2 0.0019 17.3 0.2 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 VBB32846.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB32846.1 - 0.037 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sid-5 PF17204.3 VBB32847.1 - 0.00042 20.4 0.5 0.00065 19.8 0.5 1.3 1 0 0 1 1 1 1 Sid-5 family CD34_antigen PF06365.12 VBB32847.1 - 0.0025 17.5 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Laminin_EGF PF00053.24 VBB32847.1 - 0.0041 17.2 3.0 0.0084 16.2 3.0 1.6 1 0 0 1 1 1 1 Laminin EGF domain Luteo_P1-P2 PF08467.10 VBB32847.1 - 0.019 14.2 0.9 0.023 14.0 0.9 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase EphA2_TM PF14575.6 VBB32847.1 - 0.027 15.3 1.1 0.042 14.7 0.1 1.8 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Afaf PF15339.6 VBB32847.1 - 0.044 13.5 0.1 0.076 12.7 0.0 1.4 1 1 0 1 1 1 0 Acrosome formation-associated factor DUF2207 PF09972.9 VBB32847.1 - 0.088 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CSG2 PF16965.5 VBB32847.1 - 0.15 10.9 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Pox_G9-A16 PF03003.16 VBB32847.1 - 1.9 8.2 8.1 2.3 8.0 0.2 2.5 2 1 1 3 3 3 0 Pox virus entry-fusion-complex G9/A16 Hexokinase_1 PF00349.21 VBB32848.1 - 1.1e-67 227.9 0.0 1.4e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 VBB32848.1 - 1.6e-17 63.8 0.0 2.7e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Raco_middle PF17651.1 VBB32848.1 - 0.017 14.8 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 RACo middle region FGGY_N PF00370.21 VBB32848.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain FeoC PF09012.10 VBB32848.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator AAA_29 PF13555.6 VBB32849.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain COMM_domain PF07258.14 VBB32851.1 - 5.8e-08 32.7 1.8 6.5e-08 32.6 0.4 1.7 2 0 0 2 2 2 1 COMM domain Voldacs PF03517.13 VBB32852.1 - 2.7e-27 95.6 8.3 7e-27 94.3 7.4 2.0 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling CBM_14 PF01607.24 VBB32854.1 - 1.8e-27 95.2 50.4 3e-11 43.3 4.6 5.5 3 2 2 5 5 5 5 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 VBB32854.1 - 0.0018 18.2 13.7 0.8 9.7 0.0 4.2 4 0 0 4 4 4 3 Carbohydrate binding domain (family 19) AXH PF08517.12 VBB32855.1 - 4.6e-37 127.1 0.0 8.4e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Pkinase_Tyr PF07714.17 VBB32856.1 - 7.3e-93 310.6 0.0 1.2e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB32856.1 - 1.7e-43 148.9 0.0 2.3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 VBB32856.1 - 1.5e-18 66.7 0.0 3.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 VBB32856.1 - 1.3e-14 53.5 0.2 3.5e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 VBB32856.1 - 2.4e-14 52.9 0.1 5.9e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB32856.1 - 6e-09 35.4 0.0 1.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 VBB32856.1 - 0.0027 17.8 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 VBB32856.1 - 0.031 14.6 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_4 PF06347.13 VBB32856.1 - 0.087 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain LysM PF01476.20 VBB32857.1 - 1.3e-05 25.1 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain DUF2556 PF10831.8 VBB32857.1 - 0.014 15.3 0.8 0.026 14.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Iso_dh PF00180.20 VBB32858.1 - 5.9e-104 348.0 0.0 7e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 VBB32858.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA ATP-synt_DE_N PF02823.16 VBB32861.1 - 6.6e-16 58.0 0.0 9.7e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF4175 PF13779.6 VBB32861.1 - 4.9e-05 21.5 1.6 6.1e-05 21.1 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) ATP-synt_DE PF00401.20 VBB32861.1 - 0.0036 17.5 5.2 0.0036 17.5 5.2 1.7 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Noc2 PF03715.13 VBB32863.1 - 1.4e-80 270.8 8.4 1.4e-80 270.8 8.4 2.0 2 1 1 3 3 3 1 Noc2p family RFC1 PF08519.12 VBB32863.1 - 0.019 15.1 1.1 0.061 13.5 0.4 2.2 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain RIX1 PF08167.12 VBB32863.1 - 0.48 10.1 3.8 0.19 11.4 0.5 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CH PF00307.31 VBB32865.1 - 5.3e-19 68.4 0.1 6.6e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 VBB32865.1 - 5.4e-14 51.5 0.1 8.2e-14 50.9 0.1 1.3 1 0 0 1 1 1 1 Calponin family repeat Nucleoside_tran PF01733.18 VBB32866.1 - 4.1e-14 52.7 1.3 5.8e-14 52.2 0.3 1.7 1 1 1 2 2 2 1 Nucleoside transporter MADF_DNA_bdg PF10545.9 VBB32867.1 - 0.082 13.2 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.25 VBB32868.1 - 1.2e-85 287.1 0.1 1.4e-50 172.1 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32868.1 - 1.1e-39 136.3 0.1 1.4e-24 86.7 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase PH PF00169.29 VBB32868.1 - 3e-15 56.6 0.0 1e-14 54.9 0.0 1.9 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 VBB32868.1 - 5.1e-09 36.7 2.6 1.4e-08 35.3 2.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 VBB32868.1 - 2.7e-07 30.2 0.0 5.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 VBB32868.1 - 0.013 15.9 1.3 0.37 11.2 1.3 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Haspin_kinase PF12330.8 VBB32868.1 - 0.046 12.7 1.3 0.43 9.5 0.1 2.1 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 VBB32868.1 - 0.063 12.9 0.3 0.61 9.7 0.1 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SNAP-25 PF00835.19 VBB32869.1 - 1.9e-21 76.1 0.2 4.3e-21 75.0 0.2 1.6 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 VBB32869.1 - 0.04 13.8 6.6 0.61 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 VBB32869.1 - 0.056 13.7 4.3 0.36 11.2 0.1 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus STAG PF08514.11 VBB32869.1 - 0.09 12.7 0.9 0.16 11.9 0.9 1.4 1 0 0 1 1 1 0 STAG domain SNARE PF05739.19 VBB32869.1 - 0.099 12.7 2.5 29 4.8 0.2 3.2 3 0 0 3 3 3 0 SNARE domain Rx_N PF18052.1 VBB32869.1 - 0.15 12.4 1.3 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DUF16 PF01519.16 VBB32869.1 - 0.2 12.1 3.8 2.6 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Laminin_II PF06009.12 VBB32869.1 - 0.32 11.0 5.8 4.5 7.3 5.0 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 VBB32869.1 - 0.33 11.0 5.4 6 6.9 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SOAR PF16533.5 VBB32869.1 - 0.51 10.3 4.5 3.7 7.6 0.0 2.8 2 1 1 3 3 3 0 STIM1 Orai1-activating region XhlA PF10779.9 VBB32869.1 - 0.82 9.9 6.7 2.8 8.2 0.1 2.9 2 1 0 2 2 2 0 Haemolysin XhlA TolA_bind_tri PF16331.5 VBB32869.1 - 2.8 8.1 10.8 0.21 11.7 3.7 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 VBB32869.1 - 5.2 7.8 6.0 8 7.2 1.4 2.5 2 1 0 2 2 2 0 SlyX Y_phosphatase PF00102.27 VBB32870.1 - 1.8e-70 237.1 2.2 6.9e-45 153.4 0.1 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 VBB32870.1 - 5.3e-05 23.0 0.0 0.00017 21.4 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB32870.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.7 2 1 0 2 2 2 1 Tyrosine phosphatase family Phi-29_GP16_7 PF06720.11 VBB32870.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.8 1 1 1 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 IL34 PF15036.6 VBB32870.1 - 0.043 13.9 0.3 0.1 12.6 0.3 1.6 1 0 0 1 1 1 0 Interleukin 34 CPT PF07931.12 VBB32870.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PTPlike_phytase PF14566.6 VBB32870.1 - 0.09 12.9 0.1 0.41 10.8 0.1 2.2 2 1 0 2 2 2 0 Inositol hexakisphosphate ATG101 PF07855.12 VBB32870.1 - 0.14 12.1 0.1 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Autophagy-related protein 101 Phosphodiest PF01663.22 VBB32871.1 - 3.6e-40 138.7 0.0 4.2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase 7tm_1 PF00001.21 VBB32872.1 - 2.2e-46 158.3 11.7 2.2e-46 158.3 11.7 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 VBB32872.1 - 3.2e-06 27.0 13.5 3.2e-06 27.0 13.5 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 VBB32872.1 - 0.00011 22.0 9.9 0.00029 20.7 9.9 1.7 1 1 0 1 1 1 1 Olfactory receptor MFS_1 PF07690.16 VBB32873.1 - 4.3e-38 131.1 69.3 2.6e-29 102.3 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 VBB32873.1 - 2.9e-05 23.1 4.1 2.9e-05 23.1 4.1 4.1 1 1 1 4 4 4 3 MFS_1 like family UPF0060 PF02694.15 VBB32873.1 - 0.14 12.4 0.2 0.14 12.4 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family Pkinase PF00069.25 VBB32874.1 - 1.4e-64 218.0 0.6 2.7e-64 217.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32874.1 - 4.8e-63 212.8 0.0 8.1e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 VBB32874.1 - 0.00051 19.7 1.3 0.0023 17.6 0.1 2.5 2 1 1 3 3 3 1 RIO1 family Kinase-like PF14531.6 VBB32874.1 - 0.0023 17.3 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 VBB32874.1 - 0.0047 16.9 0.1 0.015 15.2 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 VBB32874.1 - 0.0083 14.9 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 VBB32874.1 - 0.021 14.5 0.1 1.3 8.6 0.1 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pfg27 PF09216.10 VBB32874.1 - 0.21 11.4 4.6 0.14 12.0 2.6 1.7 2 0 0 2 2 2 0 Pfg27 Bac_small_YrzI PF09501.10 VBB32874.1 - 2.2 8.5 4.5 6 7.1 1.2 2.5 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) PGAP1 PF07819.13 VBB32875.1 - 0.00021 21.1 0.1 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 VBB32875.1 - 0.0038 17.8 0.1 0.0077 16.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 VBB32875.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 VBB32875.1 - 0.0077 15.4 0.0 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase GMC_oxred_N PF00732.19 VBB32876.1 - 1.4e-86 290.6 0.0 2e-86 290.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 VBB32876.1 - 3e-34 118.6 0.0 4.8e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 VBB32876.1 - 2e-05 23.8 0.0 3.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 VBB32876.1 - 0.00042 20.5 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 VBB32876.1 - 0.006 15.7 0.0 0.021 13.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 VBB32876.1 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 VBB32876.1 - 0.048 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 VBB32876.1 - 0.087 11.5 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 VBB32876.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 VBB32876.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 VBB32876.1 - 0.18 12.1 0.0 0.52 10.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 VBB32876.1 - 0.23 10.6 0.0 0.49 9.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Nuc_deoxyri_tr2 PF15891.5 VBB32877.1 - 6.7e-12 45.7 0.0 4.9e-10 39.7 0.0 3.0 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like Tubulin PF00091.25 VBB32878.1 - 4.9e-67 226.0 0.0 6.4e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB32878.1 - 8.9e-42 142.2 0.0 1.5e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 VBB32878.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain bZIP_1 PF00170.21 VBB32880.1 - 5.1e-06 26.5 7.0 1.4e-05 25.1 7.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 VBB32880.1 - 0.00027 20.9 8.0 0.00073 19.6 8.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 VBB32880.1 - 1.3 9.6 9.0 0.27 11.8 4.8 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Cpn60_TCP1 PF00118.24 VBB32881.1 - 7.1e-151 503.2 5.4 9.4e-151 502.8 5.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LSM PF01423.22 VBB32882.1 - 1e-14 54.0 0.3 1.5e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 LSM domain Borealin PF10512.9 VBB32883.1 - 0.00069 19.6 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Cut12 PF11500.8 VBB32883.1 - 0.12 12.3 0.3 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 Spindle pole body formation-associated protein YjcZ_2 PF09680.10 VBB32884.1 - 0.16 11.6 0.4 0.16 11.6 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function Innexin PF00876.18 VBB32886.1 - 2.1e-79 267.4 7.0 2.6e-79 267.1 7.0 1.0 1 0 0 1 1 1 1 Innexin tRNA-synt_1c PF00749.21 VBB32888.1 - 4.2e-22 78.4 0.0 7.2e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HEAT_2 PF13646.6 VBB32888.1 - 0.00018 21.8 0.0 0.0088 16.4 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats CECR6_TMEM121 PF14997.6 VBB32889.1 - 5.8e-28 98.0 13.8 5e-21 75.4 2.8 2.6 2 1 1 3 3 3 2 CECR6/TMEM121 family PX PF00787.24 VBB32890.1 - 1.1e-11 44.7 0.1 1.8e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 PX domain EGF PF00008.27 VBB32891.1 - 0.0024 18.1 4.2 0.0043 17.3 4.2 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 VBB32891.1 - 0.01 16.4 0.9 0.028 15.0 0.9 1.8 1 1 0 1 1 1 0 Human growth factor-like EGF Orai-1 PF07856.12 VBB32891.1 - 0.015 15.0 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity EGF_2 PF07974.13 VBB32891.1 - 0.049 14.0 6.4 0.094 13.1 6.4 1.5 1 0 0 1 1 1 0 EGF-like domain cEGF PF12662.7 VBB32891.1 - 0.1 12.6 0.9 0.25 11.3 0.9 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like TTL PF03133.15 VBB32892.1 - 1.6e-58 198.2 1.5 2.5e-58 197.5 1.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family T-box PF00907.22 VBB32893.1 - 3e-07 30.9 0.1 5.8e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 T-box Ig_3 PF13927.6 VBB32894.1 - 0.022 15.3 0.1 0.04 14.5 0.1 1.4 1 1 0 1 1 1 0 Immunoglobulin domain Evr1_Alr PF04777.13 VBB32895.1 - 8.3e-19 67.9 0.5 8.3e-19 67.9 0.5 2.2 2 0 0 2 2 2 1 Erv1 / Alr family FAD_SOX PF18371.1 VBB32895.1 - 5.1e-17 62.1 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin PF00085.20 VBB32895.1 - 4.4e-15 55.5 0.1 1.3e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin RNA_pol_L PF01193.24 VBB32895.1 - 0.047 13.1 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Thioredoxin_8 PF13905.6 VBB32895.1 - 0.079 13.3 0.2 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like GNT-I PF03071.15 VBB32896.1 - 6.1e-96 321.8 0.5 4.6e-85 286.0 0.2 2.0 1 1 1 2 2 2 2 GNT-I family Glycos_transf_2 PF00535.26 VBB32896.1 - 0.014 15.2 0.5 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 MGAT2 PF05060.14 VBB32896.1 - 0.14 11.2 0.2 0.42 9.6 0.1 1.7 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) HEAT_EZ PF13513.6 VBB32898.1 - 6.4e-17 61.7 8.0 1.7e-07 31.6 0.0 6.9 7 0 0 7 7 7 4 HEAT-like repeat HEAT PF02985.22 VBB32898.1 - 1.7e-15 55.8 19.4 0.00052 20.0 0.1 10.5 13 0 0 13 13 13 3 HEAT repeat IBN_N PF03810.19 VBB32898.1 - 1.7e-11 43.8 0.8 2.1e-09 37.2 0.0 4.3 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 VBB32898.1 - 1.2e-08 35.2 4.9 0.66 10.4 0.2 7.3 4 2 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 VBB32898.1 - 1.3e-07 31.8 4.0 0.00095 19.2 0.0 5.0 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 VBB32898.1 - 0.00022 20.9 0.1 35 3.8 0.0 5.2 2 2 2 5 5 5 0 CLASP N terminal Cnd3 PF12719.7 VBB32898.1 - 0.014 14.6 2.2 0.072 12.3 0.8 2.9 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_PBS PF03130.16 VBB32898.1 - 0.041 14.5 1.4 42 5.2 0.0 5.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TAF6_C PF07571.13 VBB32898.1 - 0.094 13.0 0.6 2.8 8.3 0.0 3.7 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 VBB32898.1 - 0.17 12.0 8.1 0.72 10.0 0.4 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GST_N_3 PF13417.6 VBB32900.1 - 1.4e-11 44.7 0.1 2.4e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 VBB32900.1 - 3.9e-10 39.8 0.1 9.4e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 VBB32900.1 - 5.1e-07 29.9 0.0 3.2e-06 27.3 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 VBB32900.1 - 0.00016 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 VBB32900.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 VBB32900.1 - 0.0031 18.2 0.2 0.042 14.6 0.0 2.5 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 VBB32900.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 VBB32900.1 - 0.0087 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Acetyltransf_16 PF05301.11 VBB32901.1 - 1.9e-54 184.1 0.0 2.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 VBB32901.1 - 0.00085 19.7 0.1 0.0056 17.1 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB32901.1 - 0.0031 17.7 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 VBB32901.1 - 0.0089 16.0 0.0 0.025 14.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ANAPC4_WD40 PF12894.7 VBB32902.1 - 3.2e-12 46.6 0.1 0.0034 17.6 0.0 5.3 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB32902.1 - 5.7e-08 33.3 3.2 1 10.4 0.4 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.12 VBB32902.1 - 0.00063 19.6 1.6 12 5.9 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 VBB32902.1 - 0.00066 17.8 0.0 0.047 11.7 0.0 2.6 2 1 1 3 3 3 1 IKI3 family DPPIV_N PF00930.21 VBB32902.1 - 0.0022 16.8 0.0 2.3 6.9 0.0 3.1 2 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 VBB32902.1 - 0.0039 17.1 0.1 0.25 11.2 0.0 2.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 VBB32902.1 - 0.0059 16.0 0.1 0.0097 15.3 0.1 1.4 1 0 0 1 1 1 1 WD40-like domain TFIIIC_delta PF12657.7 VBB32902.1 - 0.014 15.3 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Frtz PF11768.8 VBB32902.1 - 0.038 12.3 0.0 1.9 6.7 0.0 2.8 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Gmad1 PF10647.9 VBB32902.1 - 0.042 13.6 0.0 0.094 12.5 0.0 1.6 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PSII_BNR PF14870.6 VBB32902.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 HAD_2 PF13419.6 VBB32903.1 - 9.8e-21 74.6 0.0 2.4e-20 73.4 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB32903.1 - 7.3e-16 59.1 0.0 2e-15 57.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 VBB32903.1 - 2.5e-09 37.1 0.0 6.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 VBB32903.1 - 3.3e-05 24.4 0.0 0.00013 22.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 VBB32903.1 - 0.00063 19.6 0.1 2.2 8.0 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DrsE PF02635.15 VBB32903.1 - 0.02 15.2 0.1 0.17 12.2 0.0 2.2 1 1 1 2 2 2 0 DsrE/DsrF-like family Hydrolase_6 PF13344.6 VBB32903.1 - 0.11 12.6 0.1 2.3 8.4 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NTPase_1 PF03266.15 VBB32905.1 - 0.035 14.0 0.9 0.76 9.7 0.1 2.3 2 0 0 2 2 2 0 NTPase Cys_rich_KTR PF14205.6 VBB32905.1 - 0.14 12.0 0.7 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Cysteine-rich KTR ANTH PF07651.16 VBB32906.1 - 7.6e-60 202.2 0.9 7.6e-60 202.2 0.9 2.6 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 VBB32906.1 - 8.6e-49 165.7 11.0 8.6e-49 165.7 11.0 4.9 3 1 2 5 5 5 1 I/LWEQ domain FliJ PF02050.16 VBB32906.1 - 0.21 11.8 38.2 0.065 13.5 7.6 4.8 2 1 2 4 4 4 0 Flagellar FliJ protein PX PF00787.24 VBB32906.1 - 0.52 10.3 3.4 2.5 8.1 0.9 3.2 3 1 1 4 4 4 0 PX domain Sugarporin_N PF11471.8 VBB32906.1 - 3.3 7.7 14.1 1 9.4 1.3 3.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF724 PF05266.14 VBB32906.1 - 7.5 6.3 47.6 0.06 13.2 13.9 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF724) VWA PF00092.28 VBB32909.1 - 2.4e-21 76.7 1.2 6.5e-21 75.4 1.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 VBB32909.1 - 0.00047 20.8 0.0 0.002 18.8 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Phi-29_GP16_7 PF06720.11 VBB32910.1 - 0.053 13.4 0.4 0.099 12.5 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 Homeodomain PF00046.29 VBB32911.1 - 6.5e-23 80.3 3.0 6.5e-23 80.3 3.0 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB32911.1 - 0.089 12.7 1.3 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain 7tm_1 PF00001.21 VBB32912.1 - 1.4e-08 34.4 0.1 1.8e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DC_STAMP PF07782.13 VBB32912.1 - 0.0025 17.7 0.4 0.021 14.7 0.2 2.0 2 0 0 2 2 2 1 DC-STAMP-like protein KASH PF10541.9 VBB32915.1 - 1.9e-22 79.3 3.5 3.7e-22 78.3 3.5 1.5 1 0 0 1 1 1 1 Nuclear envelope localisation domain DUF4736 PF15883.5 VBB32915.1 - 4.8 6.9 10.1 0.071 12.8 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4736) KH_1 PF00013.29 VBB32916.1 - 2.6e-10 40.0 3.9 4.2e-09 36.1 0.9 2.4 2 0 0 2 2 2 2 KH domain DUF2171 PF09939.9 VBB32916.1 - 0.05 13.9 0.1 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) Homeodomain PF00046.29 VBB32917.1 - 5.7e-21 74.1 2.9 5.7e-21 74.1 2.9 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB32917.1 - 0.0061 16.4 1.1 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 VBB32917.1 - 0.059 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez TPR_1 PF00515.28 VBB32918.1 - 3.8e-41 137.3 34.2 9.4e-05 22.1 0.0 15.8 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_2 PF07719.17 VBB32918.1 - 1.1e-38 128.2 40.2 0.00028 20.8 0.0 15.8 17 0 0 17 17 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 VBB32918.1 - 2.3e-29 101.7 18.0 6.2e-06 26.6 0.0 11.4 12 1 2 14 14 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 VBB32918.1 - 2.7e-28 96.2 15.3 0.01 16.6 0.0 13.7 9 3 5 14 14 13 6 Tetratricopeptide repeat TPR_12 PF13424.6 VBB32918.1 - 2.3e-27 95.1 28.9 5.6e-05 23.4 0.4 11.4 9 4 3 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 VBB32918.1 - 2.4e-27 92.8 27.2 0.00039 20.4 0.1 13.2 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 VBB32918.1 - 1.1e-22 80.4 0.7 9.3e-08 32.6 0.0 9.4 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 VBB32918.1 - 2.5e-21 75.1 13.9 0.043 13.5 0.0 11.5 11 1 1 12 12 12 6 TPR repeat TPR_17 PF13431.6 VBB32918.1 - 2.8e-19 68.0 23.9 0.13 12.7 0.0 15.3 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_7 PF13176.6 VBB32918.1 - 2.3e-18 64.8 14.0 0.0053 16.7 0.0 11.8 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 VBB32918.1 - 1.3e-16 59.9 14.4 0.0028 17.5 0.0 11.9 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 VBB32918.1 - 3.5e-13 49.3 31.6 0.18 12.5 0.1 13.3 14 1 0 14 14 13 5 Tetratricopeptide repeat TPR_9 PF13371.6 VBB32918.1 - 1.1e-09 38.2 7.4 0.022 14.9 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 VBB32918.1 - 3.9e-07 30.1 0.2 0.25 11.4 0.0 4.8 4 0 0 4 4 4 2 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 VBB32918.1 - 9.3e-07 28.9 0.2 13 6.8 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB32918.1 - 0.00066 19.8 29.6 0.0018 18.5 1.7 7.7 5 3 4 10 10 10 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 VBB32918.1 - 0.013 15.6 16.6 0.48 10.5 0.1 6.5 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 VBB32918.1 - 0.24 11.4 21.7 12 6.0 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF4810 PF16068.5 VBB32918.1 - 0.48 11.0 0.0 0.48 11.0 0.0 4.7 5 1 0 5 5 3 0 Domain of unknown function (DUF4810) CCP_MauG PF03150.14 VBB32918.1 - 1.2 9.7 6.1 0.39 11.3 0.1 3.0 3 0 0 3 3 3 0 Di-haem cytochrome c peroxidase 3Beta_HSD PF01073.19 VBB32919.1 - 2.4e-27 95.6 0.0 3.2e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 VBB32919.1 - 8.7e-20 71.2 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 VBB32919.1 - 3.2e-13 49.5 0.0 3.3e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 VBB32919.1 - 1.2e-06 27.9 0.0 3.3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 VBB32919.1 - 2e-06 27.9 0.0 4.1e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 VBB32919.1 - 2.6e-05 23.8 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_transf_10 PF00852.19 VBB32920.1 - 1.9e-55 187.3 2.6 3e-55 186.7 2.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 VBB32920.1 - 1.8e-26 92.8 0.5 1.8e-26 92.8 0.5 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Hormone_3 PF00159.18 VBB32920.1 - 0.011 15.8 1.5 4.5 7.4 0.2 2.8 2 0 0 2 2 2 0 Pancreatic hormone peptide Eisosome1 PF12757.7 VBB32920.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Eisosome protein 1 Sugar_tr PF00083.24 VBB32921.1 - 1.5e-30 106.5 16.9 2e-30 106.1 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB32921.1 - 5.4e-16 58.5 17.7 5.8e-15 55.1 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 VBB32922.1 - 3.3e-127 425.1 13.8 4.3e-127 424.7 13.8 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 VBB32922.1 - 7.8e-15 54.6 32.9 1.4e-13 50.5 10.3 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 VBB32922.1 - 0.036 14.2 10.6 0.13 12.4 10.6 2.1 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain RbsD_FucU PF05025.13 VBB32922.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RbsD / FucU transport protein family Vut_1 PF02592.15 VBB32924.1 - 0.13 12.6 6.3 0.17 12.2 6.3 1.2 1 0 0 1 1 1 0 Putative vitamin uptake transporter DNA_pol_A PF00476.20 VBB32925.1 - 1.4e-35 123.1 0.0 2.3e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNApol_Exo PF18136.1 VBB32925.1 - 0.0038 16.4 0.4 0.0069 15.6 0.4 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain Surp PF01805.20 VBB32925.1 - 0.0041 17.1 0.9 0.0041 17.1 0.9 2.6 3 0 0 3 3 3 1 Surp module Glyco_hydro_15 PF00723.21 VBB32928.1 - 9.8e-77 258.6 0.0 1.2e-76 258.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ank_2 PF12796.7 VBB32929.1 - 3.2e-18 66.1 1.6 8.2e-09 35.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB32929.1 - 5.6e-15 55.5 2.1 3.6e-06 27.4 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB32929.1 - 2e-14 53.2 0.9 1.6e-06 28.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 VBB32929.1 - 1.7e-11 43.2 2.9 3e-06 27.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 VBB32929.1 - 1.4e-10 41.2 0.3 2.1e-06 27.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Cation_ATPase_N PF00690.26 VBB32930.1 - 7.6e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus zf-CCHC_3 PF13917.6 VBB32932.1 - 1.2e-05 25.2 0.7 1.2e-05 25.2 0.7 1.8 2 1 0 2 2 2 1 Zinc knuckle Spt5_N PF11942.8 VBB32932.1 - 0.64 11.0 6.2 0.85 10.6 6.2 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Neur_chan_memb PF02932.16 VBB32932.1 - 0.94 9.5 3.4 0.97 9.4 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-CCHC PF00098.23 VBB32932.1 - 1.3 9.3 6.2 5.6 7.2 6.2 2.2 1 1 0 1 1 1 0 Zinc knuckle KxDL PF10241.9 VBB32933.1 - 1.1e-24 86.6 1.2 1.3e-24 86.2 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein TssC PF17541.2 VBB32933.1 - 0.018 13.9 1.2 0.021 13.7 1.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Atg14 PF10186.9 VBB32933.1 - 0.075 12.1 3.1 0.079 12.0 3.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1043 PF06295.12 VBB32933.1 - 0.14 12.1 3.3 7.3 6.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) NT-C2 PF10358.9 VBB32936.1 - 1.2e-18 67.2 0.0 2.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CH PF00307.31 VBB32936.1 - 1.9e-15 57.0 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB32936.1 - 4.7e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Tho2 PF11262.8 VBB32936.1 - 0.11 11.7 1.3 0.23 10.6 1.3 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 VCX_VCY PF15231.6 VBB32937.1 - 0.11 13.2 29.8 5.7 7.6 5.0 3.2 1 1 2 3 3 3 0 Variable charge X/Y family Pkinase PF00069.25 VBB32938.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain TC1 PF15063.6 VBB32939.1 - 0.041 13.7 0.0 0.074 12.9 0.0 1.4 1 1 0 1 1 1 0 Thyroid cancer protein 1 Nuf2 PF03800.14 VBB32939.1 - 0.055 13.6 0.1 0.066 13.3 0.1 1.1 1 0 0 1 1 1 0 Nuf2 family Guanylate_cyc PF00211.20 VBB32940.1 - 2.8e-08 33.6 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ULD PF16534.5 VBB32942.1 - 1.1e-05 25.5 0.5 2.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like oligomerisation domain of SATB 7TM_GPCR_Srw PF10324.9 VBB32944.1 - 3.5e-30 105.4 4.0 4e-30 105.2 4.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 VBB32944.1 - 0.00069 19.0 2.0 0.0018 17.6 2.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TPPK_C PF12555.8 VBB32944.1 - 0.0033 17.4 0.7 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphokinase C terminal DUF1664 PF07889.12 VBB32945.1 - 0.014 15.4 0.2 0.032 14.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ArAE_2_N PF10337.9 VBB32947.1 - 0.18 10.8 0.3 0.27 10.2 0.3 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Protocadherin PF08374.11 VBB32947.1 - 0.48 10.4 4.8 0.91 9.5 4.8 1.4 1 0 0 1 1 1 0 Protocadherin HscB_4_cys PF18256.1 VBB32947.1 - 5.7 6.8 12.3 0.36 10.7 1.3 3.0 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif LRR_4 PF12799.7 VBB32948.1 - 3.5e-07 30.4 5.9 0.0044 17.4 0.0 4.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB32948.1 - 4.3e-05 23.1 0.0 9.4e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 VBB32948.1 - 0.0001 22.0 0.4 0.33 10.8 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 VBB32948.1 - 0.0002 21.1 3.4 0.95 9.7 0.2 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 VBB32948.1 - 0.0022 18.3 5.3 2.6 8.9 1.2 5.5 4 1 0 4 4 4 1 Leucine Rich Repeat Cyclin_N PF00134.23 VBB32949.1 - 3.2e-14 52.8 2.0 3.8e-12 46.1 0.4 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain AadA_C PF18280.1 VBB32949.1 - 0.11 12.6 0.1 20 5.4 0.0 2.3 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain CNOT11 PF10155.9 VBB32949.1 - 0.11 12.6 0.2 0.43 10.8 0.0 2.0 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Patched PF02460.18 VBB32950.1 - 2.6e-155 518.7 11.4 3.1e-155 518.4 11.4 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB32950.1 - 3.5e-23 82.1 1.0 3.5e-23 82.1 1.0 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SH3_14 PF18343.1 VBB32950.1 - 0.071 13.2 0.9 2.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Dda helicase SH3 domain Glyco_hydro_18 PF00704.28 VBB32951.1 - 1.6e-15 57.6 0.3 2.2e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RuBisCO_small PF00101.20 VBB32951.1 - 0.078 13.0 0.1 1.7 8.6 0.1 2.6 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain ECSCR PF15820.5 VBB32951.1 - 0.2 11.5 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Collagen PF01391.18 VBB32952.1 - 3e-24 84.5 84.6 1e-09 38.0 27.7 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) DM PF00751.18 VBB32953.1 - 1.7e-22 79.0 38.4 6.4e-13 48.4 15.7 2.4 2 0 0 2 2 2 2 DM DNA binding domain DUF4367 PF14285.6 VBB32953.1 - 0.014 15.9 3.9 0.1 13.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Glyco_tran_10_N PF17039.5 VBB32953.1 - 2.5 8.6 7.4 0.64 10.5 0.3 2.5 2 0 0 2 2 2 0 Fucosyltransferase, N-terminal ANF_receptor PF01094.28 VBB32954.1 - 2.5e-52 178.1 0.3 3.1e-52 177.8 0.3 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 VBB32954.1 - 2.5e-05 24.1 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein FAM184 PF15665.5 VBB32955.1 - 0.29 10.9 35.9 36 4.0 32.2 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 VBB32955.1 - 0.41 10.7 12.0 0.38 10.8 2.3 3.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 VBB32955.1 - 8.4 5.7 33.7 26 4.1 4.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) ZnuA PF01297.17 VBB32955.1 - 8.5 5.7 12.3 7.9 5.8 0.7 2.4 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Aconitase PF00330.20 VBB32956.1 - 4.4e-149 497.4 0.0 5.5e-149 497.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 VBB32956.1 - 7.9e-42 142.7 0.0 2.9e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 Aconitase C-terminal domain Tim17 PF02466.19 VBB32957.1 - 8.3e-26 90.5 3.0 1.5e-25 89.7 2.9 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MtN3_slv PF03083.16 VBB32958.1 - 2.3e-39 133.3 13.6 1.9e-22 79.1 0.4 3.3 2 1 1 3 3 3 3 Sugar efflux transporter for intercellular exchange Mago_nashi PF02792.14 VBB32959.1 - 4.1e-75 250.6 0.3 4.8e-75 250.4 0.3 1.1 1 0 0 1 1 1 1 Mago nashi protein T_cell_tran_alt PF15128.6 VBB32959.1 - 0.15 11.9 0.0 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AAA PF00004.29 VBB32960.1 - 7e-07 29.7 0.1 1.7e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB32960.1 - 0.0011 19.3 0.0 0.0039 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 VBB32960.1 - 0.0019 18.0 0.1 0.0034 17.2 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 VBB32960.1 - 0.002 18.1 0.3 0.0041 17.1 0.3 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 VBB32960.1 - 0.0024 17.3 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 VBB32960.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 VBB32960.1 - 0.0082 16.7 0.1 0.028 14.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 VBB32960.1 - 0.0089 16.3 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 VBB32960.1 - 0.018 14.5 0.2 0.073 12.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 VBB32960.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 VBB32960.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DsbD PF02683.15 VBB32960.1 - 0.046 13.6 0.2 0.073 13.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region PhoH PF02562.16 VBB32960.1 - 0.054 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 VBB32960.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 VBB32960.1 - 0.066 13.8 0.1 0.17 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 VBB32960.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 VBB32960.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 VBB32960.1 - 0.086 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 VBB32960.1 - 0.12 12.3 0.9 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 VBB32960.1 - 0.14 11.8 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 VBB32960.1 - 0.16 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB32960.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 VBB32960.1 - 0.21 11.3 0.2 0.37 10.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain FCH PF00611.23 VBB32961.1 - 2.4e-18 66.2 0.9 3.6e-18 65.6 0.9 1.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain MatP PF06303.12 VBB32961.1 - 0.044 14.3 0.1 0.076 13.6 0.1 1.4 1 0 0 1 1 1 0 MatP N-terminal domain NYD-SP28_assoc PF14775.6 VBB32961.1 - 0.13 12.3 1.1 0.73 10.0 0.1 2.4 3 0 0 3 3 3 0 Sperm tail C-terminal domain Pkinase PF00069.25 VBB32962.1 - 1.7e-25 89.9 0.2 2.2e-25 89.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32962.1 - 1.4e-14 54.1 0.2 1.7e-14 53.7 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB32962.1 - 0.0025 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 VBB32962.1 - 0.0072 15.1 0.2 0.0091 14.8 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 VBB32963.1 - 2.6e-89 298.9 0.0 3e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB32963.1 - 1.9e-44 152.0 0.0 2.5e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 VBB32963.1 - 7e-06 25.2 0.1 1.1e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB32963.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB32963.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SRP19 PF01922.17 VBB32964.1 - 6.3e-27 94.4 0.0 7.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein DEAD PF00270.29 VBB32965.1 - 2.6e-51 173.9 0.2 1.5e-50 171.4 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 VBB32965.1 - 4.4e-23 81.8 0.0 5.2e-22 78.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RabGAP-TBC PF00566.18 VBB32966.1 - 2.4e-49 167.9 1.3 2.4e-49 167.9 1.3 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain IER PF05760.12 VBB32967.1 - 8e-07 29.7 8.1 7.5e-06 26.5 8.1 2.5 1 1 0 1 1 1 1 Immediate early response protein (IER) Peptidase_M14 PF00246.24 VBB32968.1 - 2.2e-74 250.9 0.3 4.6e-74 249.8 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 VBB32968.1 - 3.1e-09 37.1 0.3 6.8e-09 36.0 0.3 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF2817 PF10994.8 VBB32968.1 - 0.12 11.8 0.1 26 4.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2817) Metallophos PF00149.28 VBB32969.1 - 2.7e-16 60.7 0.3 4.1e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB32969.1 - 9.8e-08 32.4 0.0 2.2e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 VBB32970.1 - 1.4e-13 51.8 0.1 2.1e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB32970.1 - 1.6e-06 28.4 0.0 9.3e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HTH_40 PF14493.6 VBB32971.1 - 0.66 10.5 4.5 0.29 11.6 0.3 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Syntaxin PF00804.25 VBB32972.1 - 8.1e-05 22.4 9.3 0.00017 21.3 9.3 1.6 1 1 0 1 1 1 1 Syntaxin DAPDH_C PF16654.5 VBB32972.1 - 0.037 13.9 0.1 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain DUF3456 PF11938.8 VBB32972.1 - 0.12 12.8 1.2 0.3 11.6 0.2 2.0 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP PCI PF01399.27 VBB32974.1 - 9.7e-12 45.3 0.1 9.7e-12 45.3 0.1 4.8 5 0 0 5 5 5 2 PCI domain DUF3928 PF13065.6 VBB32974.1 - 0.039 14.7 0.2 0.17 12.7 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) Bin3 PF06859.12 VBB32975.1 - 7.2e-25 87.7 0.0 1.5e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 VBB32975.1 - 2.4e-12 47.4 0.0 4.9e-11 43.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB32975.1 - 9.3e-12 45.1 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB32975.1 - 8.8e-11 42.4 0.0 5.4e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 VBB32975.1 - 3.9e-09 37.0 0.0 0.00076 20.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 VBB32975.1 - 5.2e-09 36.1 0.0 1.2e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 VBB32975.1 - 2.4e-07 30.5 0.0 1e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 VBB32975.1 - 1.5e-05 25.0 0.0 6.1e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 VBB32975.1 - 8.2e-05 22.1 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 VBB32975.1 - 8.8e-05 21.9 0.0 0.3 10.3 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Spermine_synth PF01564.17 VBB32975.1 - 0.00033 20.1 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 2 Spermine/spermidine synthase domain PCMT PF01135.19 VBB32975.1 - 0.0004 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 VBB32975.1 - 0.00083 19.4 0.0 0.00083 19.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 VBB32975.1 - 0.0013 18.3 0.0 0.0058 16.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 VBB32975.1 - 0.0019 17.6 0.0 0.37 10.1 0.0 2.8 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_9 PF08003.11 VBB32975.1 - 0.0057 15.6 0.1 0.0092 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 VBB32975.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.20 VBB32975.1 - 0.035 13.2 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase XRN_M PF17846.1 VBB32975.1 - 0.18 10.7 4.1 0.25 10.2 4.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain UCH PF00443.29 VBB32976.1 - 3.6e-28 98.7 0.0 6e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNA_pol_Rpc34 PF05158.12 VBB32978.1 - 3.4e-59 200.9 2.6 2.8e-58 197.9 2.6 1.9 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 VBB32978.1 - 0.00026 21.1 0.1 0.0072 16.5 0.1 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 VBB32978.1 - 0.00098 19.0 0.3 0.17 11.8 0.1 3.1 3 0 0 3 3 3 1 MarR family TFIIE_alpha PF02002.17 VBB32978.1 - 0.0013 18.6 1.1 0.18 11.7 0.1 2.3 2 0 0 2 2 2 2 TFIIE alpha subunit RPA_C PF08784.11 VBB32978.1 - 0.0023 18.6 0.5 4.1 8.1 0.0 2.4 2 0 0 2 2 2 2 Replication protein A C terminal HTH_IclR PF09339.10 VBB32978.1 - 0.003 17.3 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 VBB32978.1 - 0.0044 17.3 0.5 0.017 15.4 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulator HTH_20 PF12840.7 VBB32978.1 - 0.049 13.7 0.0 0.59 10.2 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain TrmB PF01978.19 VBB32978.1 - 0.057 13.3 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FaeA PF04703.12 VBB32978.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein GntR PF00392.21 VBB32978.1 - 0.099 12.3 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PDZ_6 PF17820.1 VBB32979.1 - 3.1e-08 33.4 0.0 3.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 VBB32979.1 - 4.9e-05 23.6 0.0 4.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB32979.1 - 0.00015 22.0 0.0 0.00018 21.8 0.0 1.1 1 0 0 1 1 1 1 PDZ domain 7tm_2 PF00002.24 VBB32982.1 - 1.4e-39 135.9 16.3 1.4e-39 135.9 16.3 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 VBB32982.1 - 2.8e-10 40.3 6.6 2.8e-10 40.3 6.6 2.6 2 0 0 2 2 2 1 Hormone receptor domain Rax2 PF12768.7 VBB32982.1 - 0.0045 16.5 1.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 2 Cortical protein marker for cell polarity Ninjurin PF04923.12 VBB32982.1 - 2.2 8.3 6.6 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 Ninjurin DUF4006 PF13179.6 VBB32982.1 - 9 6.3 7.5 3.1 7.8 0.3 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF4006) DUF1751 PF08551.10 VBB32983.1 - 9.5e-15 55.0 6.9 2e-14 53.9 6.9 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Mob1_phocein PF03637.17 VBB32984.1 - 4.2e-28 98.5 0.3 1.1e-27 97.1 0.3 1.7 1 0 0 1 1 1 1 Mob1/phocein family Rad51 PF08423.11 VBB32984.1 - 6.5e-17 61.6 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 VBB32984.1 - 9.1e-05 21.9 0.6 0.00019 20.8 0.0 1.9 2 0 0 2 2 2 1 KaiC RecA PF00154.21 VBB32984.1 - 0.0005 19.6 0.0 0.00096 18.7 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DUF2113 PF09886.9 VBB32984.1 - 0.017 14.5 0.5 0.037 13.4 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) DUF445 PF04286.12 VBB32984.1 - 0.076 12.8 9.0 0.16 11.7 9.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RecX PF02631.16 VBB32984.1 - 0.33 11.4 2.4 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 RecX family UPF0004 PF00919.20 VBB32985.1 - 2.4e-21 75.6 0.0 4.5e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 VBB32985.1 - 0.0006 20.2 0.0 0.002 18.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily RhoGAP PF00620.27 VBB32986.1 - 1.8e-23 83.0 0.0 3.3e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 VBB32986.1 - 2.2e-20 73.2 0.0 5.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 VBB32986.1 - 5.3e-09 36.0 7.7 1.4e-05 25.1 4.5 2.6 2 0 0 2 2 2 2 WW domain ABC_membrane_2 PF06472.15 VBB32987.1 - 2.5e-56 191.1 4.5 3.3e-56 190.7 4.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 VBB32987.1 - 3.9e-15 56.6 0.0 7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 VBB32987.1 - 0.00045 20.0 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 VBB32987.1 - 0.00053 20.0 0.1 0.0042 17.0 0.1 2.5 3 0 0 3 3 3 1 NACHT domain RsgA_GTPase PF03193.16 VBB32987.1 - 0.0008 19.3 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 VBB32987.1 - 0.0015 19.0 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 VBB32987.1 - 0.0038 17.6 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 VBB32987.1 - 0.0052 16.6 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 VBB32987.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 VBB32987.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB32987.1 - 0.022 15.1 0.6 0.25 11.7 0.1 2.6 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 VBB32987.1 - 0.051 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 VBB32987.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 VBB32987.1 - 0.085 13.1 0.3 0.35 11.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 VBB32987.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 VBB32987.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 VBB32987.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 VBB32987.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 VBB32987.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 VBB32987.1 - 0.2 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 NTPase Oxysterol_BP PF01237.18 VBB32988.1 - 2.7e-120 401.6 3.4 3.1e-120 401.4 3.4 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Lipase_2 PF01674.18 VBB32990.1 - 9.9e-53 178.9 0.2 9.9e-53 178.9 0.2 1.3 2 0 0 2 2 2 1 Lipase (class 2) Palm_thioest PF02089.15 VBB32990.1 - 3.4e-06 27.1 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 VBB32990.1 - 0.00085 19.1 0.3 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 VBB32990.1 - 0.0025 17.0 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 VBB32990.1 - 0.0065 17.1 0.0 0.0083 16.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 VBB32990.1 - 0.044 13.3 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.12 VBB32990.1 - 0.047 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 VBB32990.1 - 0.099 11.9 0.5 0.28 10.4 0.5 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Yip1 PF04893.17 VBB32991.1 - 8.1e-12 45.2 13.9 1.4e-11 44.4 13.9 1.4 1 1 0 1 1 1 1 Yip1 domain LisH_2 PF16045.5 VBB32991.1 - 0.021 13.9 0.3 0.073 12.1 0.3 2.0 1 0 0 1 1 1 0 LisH zf-RanBP PF00641.18 VBB32992.1 - 9.3e-10 37.7 14.2 6.5e-07 28.6 6.6 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Pkinase PF00069.25 VBB32993.1 - 3.6e-57 193.7 0.0 1.8e-56 191.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB32993.1 - 2.4e-31 109.0 0.0 4.3e-30 104.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB32993.1 - 8.2e-06 24.8 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 VBB32993.1 - 9.7e-05 21.8 0.0 0.00063 19.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 VBB32993.1 - 0.014 15.0 0.2 4.5 6.8 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-C2H2 PF00096.26 VBB32994.1 - 2.5e-14 52.8 26.8 9.6e-05 22.6 3.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB32994.1 - 6.6e-13 48.4 27.5 4.5e-09 36.3 1.2 4.9 5 1 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB32994.1 - 3.9e-10 39.7 25.6 0.0012 19.5 0.8 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 VBB32994.1 - 0.00015 22.5 17.3 0.11 13.2 1.1 3.6 3 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 VBB32994.1 - 0.00067 19.2 7.6 3.2 7.4 1.4 4.4 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 VBB32994.1 - 0.0094 15.7 3.5 0.0094 15.7 3.5 3.6 4 0 0 4 4 3 2 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 VBB32994.1 - 0.072 13.0 0.1 0.072 13.0 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 VBB32994.1 - 0.11 12.8 8.8 1.2 9.5 0.2 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 VBB32994.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.5 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 VBB32994.1 - 0.27 11.1 25.1 0.18 11.6 2.1 4.5 5 0 0 5 5 5 0 zinc-finger C2H2-type ADK_lid PF05191.14 VBB32994.1 - 0.68 10.0 9.3 0.44 10.6 3.6 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 VBB32994.1 - 0.76 10.0 16.5 5.3 7.2 0.8 4.3 3 1 2 5 5 5 0 Zinc ribbon domain XPA_N PF01286.18 VBB32994.1 - 0.82 9.8 12.9 5.6 7.1 0.1 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Rubredoxin_2 PF18073.1 VBB32994.1 - 0.86 9.4 0.1 0.86 9.4 0.1 3.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain zinc_ribbon_15 PF17032.5 VBB32994.1 - 1.1 10.0 10.5 1.9 9.3 0.7 2.5 1 1 0 2 2 2 0 zinc-ribbon family zf-met PF12874.7 VBB32994.1 - 1.2 9.6 20.5 0.83 10.1 2.1 4.6 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 VBB32994.1 - 1.3 9.1 27.0 0.15 12.1 3.7 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-dskA_traR PF01258.17 VBB32994.1 - 1.3 9.0 5.6 6.3 6.8 0.0 3.1 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2H2_2 PF12756.7 VBB32994.1 - 1.7 9.0 15.1 10 6.5 0.2 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 VBB32994.1 - 3.4 7.6 12.0 0.39 10.6 0.4 3.3 1 1 2 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3446 PF11928.8 VBB32994.1 - 5.1 7.5 11.8 0.16 12.3 2.1 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain zf-MYST PF17772.1 VBB32994.1 - 6.2 6.5 10.1 8.5 6.1 0.1 4.1 3 1 1 4 4 4 0 MYST family zinc finger domain zf-trcl PF13451.6 VBB32994.1 - 7.7 6.5 11.1 26 4.8 0.1 4.0 4 0 0 4 4 4 0 Probable zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 VBB32994.1 - 8.4 6.5 8.7 75 3.5 0.3 3.8 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger Ion_trans PF00520.31 VBB32995.1 - 1.4e-19 70.3 15.7 2.7e-19 69.4 15.7 1.4 1 0 0 1 1 1 1 Ion transport protein TRPM_tetra PF16519.5 VBB32995.1 - 6.7e-06 26.1 5.6 9.5e-05 22.4 2.5 2.6 2 0 0 2 2 2 2 Tetramerisation domain of TRPM PI3_PI4_kinase PF00454.27 VBB32996.1 - 3.3e-26 92.6 0.0 8.2e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Peptidase_M14 PF00246.24 VBB32997.1 - 6.3e-92 308.5 0.0 8.3e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 VBB32997.1 - 4.9e-19 68.5 0.2 1.5e-18 66.9 0.2 1.9 1 0 0 1 1 1 1 Carboxypeptidase activation peptide VWA PF00092.28 VBB32998.1 - 8.1e-51 172.7 0.3 2.3e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 VBB32998.1 - 5.6e-25 88.1 1.3 8.8e-12 45.6 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 VBB32998.1 - 0.00016 21.1 0.3 0.044 13.2 0.0 2.5 2 1 0 2 2 2 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 VBB32998.1 - 0.00042 20.5 0.1 0.013 15.6 0.0 2.5 2 1 0 2 2 2 1 vWA found in TerF C terminus CCDC53 PF10152.9 VBB32998.1 - 0.0041 17.5 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex SSP160 PF06933.11 VBB32998.1 - 0.028 12.7 7.7 0.035 12.3 7.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PurL_C PF16904.5 VBB32998.1 - 0.087 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus Mucin PF01456.17 VBB32998.1 - 0.11 12.5 15.3 0.18 11.8 15.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 VBB32998.1 - 0.21 11.5 9.1 0.37 10.7 9.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.12 VBB32998.1 - 2.4 6.0 8.1 3.4 5.5 8.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Bravo_FIGEY PF13882.6 VBB32999.1 - 9.7e-21 74.9 2.7 1.8e-20 74.1 2.7 1.5 1 0 0 1 1 1 1 Bravo-like intracellular region DUF2207 PF09972.9 VBB32999.1 - 0.00047 19.0 0.0 0.00063 18.6 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Herpes_gE PF02480.16 VBB32999.1 - 0.0015 17.4 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E WBP-1 PF11669.8 VBB32999.1 - 0.009 16.6 0.1 0.079 13.6 0.0 2.1 2 0 0 2 2 2 1 WW domain-binding protein 1 EphA2_TM PF14575.6 VBB32999.1 - 0.012 16.5 0.0 0.058 14.3 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM156 PF15106.6 VBB32999.1 - 0.021 14.2 0.5 0.036 13.5 0.5 1.3 1 0 0 1 1 1 0 TMEM156 protein family fn3 PF00041.21 VBB32999.1 - 0.023 15.0 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain TMEM154 PF15102.6 VBB32999.1 - 0.028 14.3 0.0 0.028 14.3 0.0 1.6 2 0 0 2 2 1 0 TMEM154 protein family LYRIC PF15686.5 VBB32999.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SIT PF15330.6 VBB32999.1 - 0.032 14.7 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT BatD PF13584.6 VBB32999.1 - 0.033 13.0 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance SID-1_RNA_chan PF13965.6 VBB32999.1 - 0.044 12.2 0.0 0.064 11.7 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4381 PF14316.6 VBB32999.1 - 0.1 12.9 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMIE PF16038.5 VBB32999.1 - 0.1 12.5 0.5 0.1 12.5 0.5 1.6 2 0 0 2 2 1 0 TMIE protein tRNA_anti-like PF12869.7 VBB32999.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 tRNA_anti-like VirB8 PF04335.13 VBB32999.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein Hum_adeno_E3A PF05393.11 VBB32999.1 - 0.13 12.2 0.3 0.13 12.2 0.3 1.7 2 0 0 2 2 1 0 Human adenovirus early E3A glycoprotein SARAF PF06682.12 VBB32999.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis OATP PF03137.20 VBB32999.1 - 0.14 10.4 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pur_ac_phosph_N PF16656.5 VBB32999.1 - 0.16 12.5 0.0 0.41 11.2 0.0 1.8 2 1 0 2 2 1 0 Purple acid Phosphatase, N-terminal domain RCR PF12273.8 VBB32999.1 - 0.21 12.3 2.5 1.7 9.3 3.1 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red ATP-synt_8 PF00895.20 VBB32999.1 - 3.8 8.1 8.9 3.2 8.3 6.6 1.9 2 0 0 2 2 2 0 ATP synthase protein 8 NIDO PF06119.14 VBB33000.1 - 4.6e-29 101.2 1.7 3.7e-16 59.8 0.8 2.4 2 0 0 2 2 2 2 Nidogen-like cEGF PF12662.7 VBB33000.1 - 1.2e-07 31.5 12.4 0.00029 20.7 3.4 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.7 VBB33000.1 - 2.4e-07 30.8 6.4 2.4e-07 30.8 6.4 3.4 3 2 0 3 3 3 2 EGF domain EGF_CA PF07645.15 VBB33000.1 - 9.1e-07 29.0 7.6 9.1e-07 29.0 7.6 3.9 2 1 1 3 3 3 1 Calcium-binding EGF domain Astacin PF01400.24 VBB33001.1 - 3.9e-66 222.3 0.0 6.3e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Tetraspanin PF00335.20 VBB33002.1 - 2e-42 145.5 10.4 2.4e-42 145.2 10.4 1.1 1 0 0 1 1 1 1 Tetraspanin family CCG PF02754.16 VBB33002.1 - 0.16 12.2 1.3 30 4.9 0.1 3.2 3 0 0 3 3 3 0 Cysteine-rich domain DUF3810 PF12725.7 VBB33002.1 - 0.23 10.7 1.6 0.47 9.7 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2569 PF10754.9 VBB33002.1 - 0.55 10.7 5.9 1 9.8 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4870 PF09685.10 VBB33002.1 - 5.9 7.0 13.5 0.46 10.6 6.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Ski_Sno PF02437.17 VBB33003.1 - 2.4e-18 65.8 0.5 4.7e-18 64.9 0.5 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family PapC_N PF13954.6 VBB33003.1 - 0.029 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 PapC N-terminal domain Skp1 PF01466.19 VBB33004.1 - 5e-23 81.0 0.2 5e-23 81.0 0.2 2.1 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 VBB33004.1 - 2.8e-10 40.2 0.5 7e-10 38.9 0.5 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain HSP20 PF00011.21 VBB33005.1 - 4.7e-12 45.9 0.2 5.9e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family EB1 PF03271.17 VBB33006.1 - 6.9e-11 42.2 1.0 1.4e-10 41.3 1.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 VBB33006.1 - 1.2e-07 31.8 0.8 1.2e-07 31.8 0.8 2.0 3 0 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB33006.1 - 0.0041 16.9 0.0 0.0096 15.7 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain HSP20 PF00011.21 VBB33007.1 - 4.7e-12 45.9 0.2 5.9e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Glycohydro_20b2 PF14845.6 VBB33008.1 - 3.1e-19 70.0 0.0 3.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 VBB33008.1 - 5.1e-06 27.3 0.0 7.5e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 VBB33009.1 - 1.1e-55 189.4 1.9 1.7e-42 146.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Ion_trans_2 PF07885.16 VBB33010.1 - 2.1e-32 110.9 16.0 7.5e-16 57.9 0.8 3.1 3 0 0 3 3 3 2 Ion channel Sigma_reg_N PF13800.6 VBB33010.1 - 2.4 8.5 9.1 4.7 7.6 0.0 3.8 4 0 0 4 4 4 0 Sigma factor regulator N-terminal PH PF00169.29 VBB33011.1 - 1e-09 38.9 1.3 2.6e-09 37.5 1.3 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 VBB33011.1 - 6 7.3 9.1 0.17 12.3 2.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain bZIP_2 PF07716.15 VBB33012.1 - 4.3e-09 36.3 29.9 4.6e-08 33.0 21.2 3.3 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 VBB33012.1 - 3.8e-05 23.7 16.6 3.8e-05 23.7 16.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor SUIM_assoc PF16619.5 VBB33012.1 - 0.0011 18.9 5.4 0.0011 18.9 5.4 3.6 4 0 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 GSHPx PF00255.19 VBB33014.1 - 5.1e-32 109.7 0.8 7.1e-32 109.2 0.8 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 VBB33014.1 - 0.05 13.5 0.1 0.085 12.8 0.1 1.6 1 1 0 1 1 1 0 AhpC/TSA family Lipoprotein_15 PF03640.15 VBB33014.1 - 0.084 12.4 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Secreted repeat of unknown function Pkinase_Tyr PF07714.17 VBB33015.1 - 3.5e-90 301.8 0.0 4.6e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB33015.1 - 2.9e-35 121.9 0.0 2.3e-26 92.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain UPF0640 PF15114.6 VBB33015.1 - 0.088 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 C2 PF00168.30 VBB33016.1 - 6.1e-08 32.9 0.0 1.5e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 C2 domain DUF5451 PF17532.2 VBB33016.1 - 0.0086 16.4 3.5 0.017 15.4 3.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5451) CaKB PF03185.15 VBB33017.1 - 0.099 12.3 0.3 0.24 11.0 0.3 1.6 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Mito_carr PF00153.27 VBB33018.1 - 5.6e-47 157.6 1.6 1.4e-18 66.6 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Peptidase_C97 PF05903.14 VBB33019.1 - 8.5e-43 145.8 0.0 1.2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain TUTF7_u4 PF16631.5 VBB33020.1 - 0.057 14.0 1.1 0.61 10.8 0.2 2.7 2 0 0 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 Ras PF00071.22 VBB33021.1 - 3.8e-14 52.6 1.8 4.2e-14 52.5 0.2 1.9 2 0 0 2 2 2 1 Ras family DUF1827 PF08860.10 VBB33021.1 - 0.025 14.8 0.1 0.071 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) DUF4663 PF15668.5 VBB33021.1 - 0.067 12.3 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) RINGv PF12906.7 VBB33022.1 - 8.6e-12 45.0 9.4 8.6e-12 45.0 9.4 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 VBB33022.1 - 0.0041 17.4 11.1 0.024 15.0 8.5 3.1 2 1 1 3 3 3 2 Ring finger domain Sprouty PF05210.13 VBB33022.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.5 3 0 0 3 3 3 0 Sprouty protein (Spry) zf-ANAPC11 PF12861.7 VBB33022.1 - 0.61 10.2 7.3 0.18 11.9 3.1 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 VBB33022.1 - 4.5 7.6 10.2 1.2e+02 3.0 10.5 2.9 1 1 1 2 2 2 0 RING-H2 zinc finger domain Mesd PF10185.9 VBB33023.1 - 8.6e-36 123.2 5.2 3.9e-35 121.1 3.2 2.8 2 2 1 3 3 3 1 Chaperone for wingless signalling and trafficking of LDL receptor UBA_4 PF14555.6 VBB33023.1 - 3.8e-08 33.0 0.0 8.4e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain TraB PF01963.17 VBB33023.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 TraB family Mesd PF10185.9 VBB33024.1 - 1.1e-36 126.1 3.2 6.3e-36 123.7 3.2 1.8 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor TraB PF01963.17 VBB33024.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 TraB family FRG1 PF06229.12 VBB33025.1 - 2.6e-61 206.7 0.3 2.6e-61 206.7 0.3 1.3 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 VBB33025.1 - 1.6e-05 25.1 0.0 0.00013 22.2 0.0 2.3 2 1 1 3 3 3 1 Fascin domain DUF1754 PF08555.10 VBB33025.1 - 0.0091 16.8 1.2 0.0091 16.8 1.2 2.3 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MFS_1 PF07690.16 VBB33026.1 - 2.2e-34 118.9 33.6 1.2e-32 113.2 34.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 VBB33026.1 - 6e-12 44.6 28.9 1.3e-07 30.3 0.7 4.2 2 2 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 VBB33026.1 - 7.8e-12 44.8 13.3 7.8e-12 44.8 13.3 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter YrhC PF14143.6 VBB33026.1 - 4.7 7.4 6.7 0.98 9.6 0.7 3.0 3 0 0 3 3 3 0 YrhC-like protein MIF4G PF02854.19 VBB33027.1 - 0.044 13.4 0.7 0.074 12.7 0.1 1.7 2 0 0 2 2 2 0 MIF4G domain Pro_isomerase PF00160.21 VBB33028.1 - 5.9e-39 133.9 1.0 1.3e-38 132.8 0.1 2.0 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 VBB33028.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 VBB33028.1 - 0.058 13.2 0.2 0.62 9.9 0.2 2.5 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PRCH PF03967.13 VBB33028.1 - 0.12 12.6 0.3 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region bZIP_2 PF07716.15 VBB33030.1 - 4e-10 39.6 18.9 4e-10 39.6 18.9 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 VBB33030.1 - 0.00024 21.1 17.3 0.00024 21.1 17.3 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 VBB33030.1 - 0.023 15.2 15.6 0.023 15.2 15.6 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor PA26 PF04636.13 VBB33030.1 - 0.072 12.0 1.5 0.088 11.7 1.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Mito_fiss_reg PF05308.11 VBB33030.1 - 0.075 13.1 23.3 1.2 9.1 16.7 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator UPF0242 PF06785.11 VBB33030.1 - 0.62 10.1 12.3 1 9.5 12.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3292 PF11696.8 VBB33030.1 - 0.62 8.4 6.1 0.76 8.1 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) VIR_N PF15912.5 VBB33030.1 - 3.1 7.3 14.8 6.4 6.3 14.8 1.5 1 1 0 1 1 1 0 Virilizer, N-terminal PRKCSH-like PF12999.7 VBB33030.1 - 3.4 7.5 5.1 5 6.9 5.1 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF3410 PF11890.8 VBB33030.1 - 4 7.3 9.5 21 5.0 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3410) Rep_fac-A_C PF08646.10 VBB33031.1 - 8.8e-40 135.8 6.3 2.1e-39 134.6 3.5 2.5 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 VBB33031.1 - 8.7e-24 83.3 0.7 6.1e-20 71.0 0.1 3.2 3 1 0 3 3 3 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 VBB33031.1 - 2.3e-14 53.1 2.7 1.2e-09 38.0 0.2 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 VBB33031.1 - 2.7e-07 30.5 0.0 7.6e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.14 VBB33031.1 - 0.0017 18.6 0.0 0.021 15.1 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF223 SSB PF00436.25 VBB33031.1 - 0.019 15.0 0.1 0.25 11.4 0.0 2.8 2 1 0 2 2 2 0 Single-strand binding protein family C1_2 PF03107.16 VBB33031.1 - 0.025 14.9 1.0 0.052 13.9 1.0 1.5 1 0 0 1 1 1 0 C1 domain Mor PF08765.11 VBB33032.1 - 0.1 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Mor transcription activator family DUF572 PF04502.13 VBB33033.1 - 1.3e-75 255.1 4.0 1.5e-75 254.9 4.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.11 VBB33033.1 - 0.16 11.9 1.0 3.9 7.5 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) LisH PF08513.11 VBB33034.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 LisH zf-C3Hc3H PF13891.6 VBB33035.1 - 2.1e-16 60.0 26.8 1.1e-09 38.5 4.6 3.4 2 1 0 2 2 2 2 Potential DNA-binding domain DUF4175 PF13779.6 VBB33035.1 - 3.6 5.4 24.3 5.1 4.9 24.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EPL1 PF10513.9 VBB33035.1 - 4.2 7.8 13.4 1.8 8.9 9.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like CD20 PF04103.15 VBB33036.1 - 0.0054 16.8 1.7 0.0085 16.2 1.7 1.2 1 0 0 1 1 1 1 CD20-like family CBFD_NFYB_HMF PF00808.23 VBB33037.1 - 1.8e-10 40.9 0.2 1.8e-10 40.9 0.2 2.0 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB33037.1 - 2.6e-06 27.8 0.2 2.6e-06 27.8 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Branch PF02485.21 VBB33038.1 - 5.6e-17 62.1 0.0 8.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme PDZ PF00595.24 VBB33039.1 - 1.1e-32 112.2 7.1 9.6e-17 61.1 0.7 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 VBB33039.1 - 2.5e-14 52.9 0.6 4.1e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 VBB33039.1 - 6.6e-09 36.0 3.1 0.0078 16.5 0.1 3.6 3 0 0 3 3 3 2 PDZ domain DBB PF14545.6 VBB33039.1 - 0.0052 16.7 0.2 1.3 9.0 0.2 2.5 2 0 0 2 2 2 2 Dof, BCAP, and BANK (DBB) motif, PDZ_4 PF17816.1 VBB33039.1 - 0.024 15.0 0.0 5.7 7.4 0.0 3.3 3 0 0 3 3 3 0 PDZ domain GRASP55_65 PF04495.14 VBB33039.1 - 0.035 14.4 0.1 0.42 10.9 0.0 2.4 2 1 0 2 2 2 0 GRASP55/65 PDZ-like domain DUF2577 PF10844.8 VBB33039.1 - 0.043 14.0 0.2 8.5 6.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2577) AAA_5 PF07728.14 VBB33041.1 - 9.2e-91 301.0 0.0 1.8e-27 96.0 0.0 6.6 6 1 0 6 6 6 6 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 VBB33041.1 - 3.4e-23 81.9 0.0 7.6e-07 29.1 0.0 5.9 5 1 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 VBB33041.1 - 7e-22 77.6 1.3 5.1e-11 42.7 0.1 3.0 2 0 0 2 2 2 2 Midasin AAA lid domain AAA PF00004.29 VBB33041.1 - 5.2e-19 69.0 0.0 0.00067 20.1 0.0 5.2 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 VBB33041.1 - 5.2e-18 65.3 0.2 0.0007 19.7 0.0 5.8 6 0 0 6 6 5 3 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 VBB33041.1 - 1.8e-14 54.5 2.4 0.041 14.3 0.0 5.6 5 1 0 6 6 5 4 AAA ATPase domain AAA_7 PF12775.7 VBB33041.1 - 6.2e-14 51.9 3.9 0.00066 19.2 0.0 5.2 6 0 0 6 6 4 4 P-loop containing dynein motor region Rad17 PF03215.15 VBB33041.1 - 1.5e-13 51.0 3.2 0.017 15.1 0.0 4.6 4 0 0 4 4 4 3 Rad17 P-loop domain AAA_14 PF13173.6 VBB33041.1 - 2.2e-13 50.4 0.0 0.017 15.1 0.0 5.8 6 0 0 6 6 5 3 AAA domain AAA_lid_5 PF17865.1 VBB33041.1 - 1.9e-12 47.2 0.1 1.8e-11 44.1 0.1 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain ABC_tran PF00005.27 VBB33041.1 - 5.9e-12 46.3 0.9 0.0041 17.6 0.0 4.5 4 0 0 4 4 4 2 ABC transporter AAA_6 PF12774.7 VBB33041.1 - 1.6e-11 43.8 2.9 0.8 8.6 0.1 8.0 7 1 0 7 7 7 2 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 VBB33041.1 - 7.2e-11 42.2 0.0 0.012 15.4 0.0 5.4 5 1 0 5 5 5 2 AAA domain AAA_18 PF13238.6 VBB33041.1 - 5.4e-10 39.9 0.4 0.37 11.3 0.0 5.0 5 0 0 5 5 4 3 AAA domain Sigma54_activat PF00158.26 VBB33041.1 - 5.8e-10 39.1 0.1 0.0041 16.9 0.0 5.7 6 0 0 6 6 6 1 Sigma-54 interaction domain RNA_helicase PF00910.22 VBB33041.1 - 1.6e-09 38.1 1.2 0.34 11.3 0.0 5.2 5 0 0 5 5 4 1 RNA helicase Mg_chelatase PF01078.21 VBB33041.1 - 2.4e-09 36.9 3.9 1.5 8.2 0.1 6.7 7 1 1 8 8 7 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 VBB33041.1 - 3.5e-09 36.9 0.0 0.64 10.2 0.0 4.6 4 0 0 4 4 4 3 AAA domain AAA_22 PF13401.6 VBB33041.1 - 8.4e-09 35.8 8.5 0.025 14.9 0.0 6.3 7 1 0 7 7 4 2 AAA domain AAA_29 PF13555.6 VBB33041.1 - 9.7e-09 34.8 0.9 0.11 12.3 0.1 4.5 4 0 0 4 4 4 3 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 VBB33041.1 - 1e-08 35.2 0.0 0.13 12.0 0.0 4.9 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 VBB33041.1 - 2.8e-08 33.9 4.2 0.17 11.8 0.0 5.1 5 0 0 5 5 4 2 NACHT domain TsaE PF02367.17 VBB33041.1 - 9e-08 32.2 0.7 0.44 10.5 0.0 4.4 4 0 0 4 4 4 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 VBB33041.1 - 1.6e-07 31.5 0.2 0.021 15.0 0.0 5.0 5 1 1 6 6 4 1 Sigma-54 interaction domain AAA_25 PF13481.6 VBB33041.1 - 2.1e-07 30.7 2.6 0.22 11.1 0.0 4.3 4 0 0 4 4 4 2 AAA domain DUF815 PF05673.13 VBB33041.1 - 3e-06 26.6 0.1 0.29 10.2 0.0 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 VBB33041.1 - 9.1e-06 26.0 6.1 0.2 11.9 0.1 4.5 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 VBB33041.1 - 1.6e-05 24.1 0.0 3.1 6.8 0.0 4.4 4 0 0 4 4 4 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 VBB33041.1 - 1.7e-05 24.2 0.1 2.1 7.5 0.0 4.6 5 0 0 5 5 4 1 Zeta toxin AAA_23 PF13476.6 VBB33041.1 - 1.8e-05 25.3 3.5 0.41 11.1 0.0 4.4 5 0 0 5 5 3 1 AAA domain RuvB_N PF05496.12 VBB33041.1 - 2.1e-05 24.3 1.5 0.14 11.9 0.0 4.4 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 VBB33041.1 - 3.7e-05 23.6 0.6 0.32 10.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 VBB33041.1 - 4.5e-05 23.3 1.8 0.69 9.6 0.0 3.8 4 1 0 4 4 4 2 AAA ATPase domain PduV-EutP PF10662.9 VBB33041.1 - 4.6e-05 23.2 0.6 0.0037 17.0 0.0 3.7 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_8 PF12780.7 VBB33041.1 - 6.1e-05 22.5 0.1 1.3 8.3 0.1 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 RsgA_GTPase PF03193.16 VBB33041.1 - 8.2e-05 22.6 0.3 3.9 7.4 0.0 4.3 4 0 0 4 4 4 0 RsgA GTPase TIP49 PF06068.13 VBB33041.1 - 0.00013 21.3 0.7 4 6.5 0.0 4.3 5 0 0 5 5 4 0 TIP49 P-loop domain IstB_IS21 PF01695.17 VBB33041.1 - 0.00026 20.8 0.0 1.4 8.6 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein dNK PF01712.19 VBB33041.1 - 0.0016 18.4 3.8 23 4.8 0.0 4.7 4 0 0 4 4 4 0 Deoxynucleoside kinase DUF87 PF01935.17 VBB33041.1 - 0.0016 18.6 0.5 1 9.4 0.5 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain NB-ARC PF00931.22 VBB33041.1 - 0.0017 17.6 0.1 2.6 7.1 0.0 3.8 4 0 0 4 4 3 1 NB-ARC domain SRP54 PF00448.22 VBB33041.1 - 0.0029 17.3 4.2 1.1 8.8 0.0 3.7 4 0 0 4 4 3 1 SRP54-type protein, GTPase domain ATPase PF06745.13 VBB33041.1 - 0.0036 16.7 0.1 9.8 5.4 0.0 4.1 4 0 0 4 4 4 0 KaiC CPT PF07931.12 VBB33041.1 - 0.004 17.0 4.4 42 3.9 0.0 6.6 8 1 0 8 8 6 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 VBB33041.1 - 0.005 17.2 3.3 8.7 6.7 0.1 4.8 4 0 0 4 4 3 0 AAA domain PhoH PF02562.16 VBB33041.1 - 0.0097 15.4 0.2 3 7.2 0.0 3.4 4 0 0 4 4 3 0 PhoH-like protein DEAD PF00270.29 VBB33041.1 - 0.013 15.2 0.0 5.6 6.7 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 VBB33041.1 - 0.016 15.3 0.1 31 4.7 0.0 4.2 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_11 PF13086.6 VBB33041.1 - 0.026 14.3 0.0 0.6 9.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 VBB33041.1 - 0.029 13.8 0.2 8.1 5.8 0.0 3.5 4 0 0 4 4 3 0 Bacterial TniB protein IPT PF01745.16 VBB33041.1 - 0.029 13.8 3.8 1.8 7.9 0.0 3.6 4 0 0 4 4 3 0 Isopentenyl transferase AAA_2 PF07724.14 VBB33041.1 - 0.032 14.4 0.1 34 4.5 0.0 4.5 5 0 0 5 5 4 0 AAA domain (Cdc48 subfamily) FtsK_SpoIIIE PF01580.18 VBB33041.1 - 0.035 13.4 0.1 2.4 7.4 0.1 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family ResIII PF04851.15 VBB33041.1 - 0.041 13.9 0.1 7 6.6 0.0 3.7 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Roc PF08477.13 VBB33041.1 - 0.072 13.3 0.7 2 8.7 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 VBB33041.1 - 0.078 12.8 1.0 1.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein VirE PF05272.11 VBB33041.1 - 0.079 12.7 0.0 5.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Virulence-associated protein E Thymidylate_kin PF02223.17 VBB33041.1 - 0.081 12.6 0.1 2.9 7.5 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase SKI PF01202.22 VBB33041.1 - 0.093 12.9 1.5 4.2 7.5 0.0 3.5 3 0 0 3 3 3 0 Shikimate kinase AAA_21 PF13304.6 VBB33041.1 - 0.11 12.3 0.8 1.8 8.3 0.1 2.7 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 VBB33041.1 - 0.12 12.0 0.1 0.71 9.5 0.0 2.3 3 0 0 3 3 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 VBB33041.1 - 0.15 11.9 2.8 68 3.3 0.1 3.7 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.6 VBB33041.1 - 0.21 12.0 2.6 76 3.7 0.1 3.7 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 VBB33041.1 - 0.4 9.8 4.5 13 4.8 0.0 3.8 5 0 0 5 5 4 0 G-protein alpha subunit AI-2E_transport PF01594.16 VBB33042.1 - 0.54 9.4 10.0 1.6 7.8 10.0 1.7 1 1 0 1 1 1 0 AI-2E family transporter LRR_4 PF12799.7 VBB33043.1 - 0.29 11.6 4.9 22 5.7 0.2 4.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) MCM_OB PF17207.3 VBB33044.1 - 0.062 13.1 2.1 0.64 9.9 1.7 2.3 2 0 0 2 2 2 0 MCM OB domain Nuc_recep-AF1 PF11825.8 VBB33044.1 - 0.35 10.9 8.3 0.64 10.1 8.3 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 LRR_8 PF13855.6 VBB33045.1 - 3.4e-29 100.4 38.7 1.5e-11 43.8 2.6 5.9 2 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 VBB33045.1 - 3.3e-18 65.5 43.2 9.4e-06 25.9 0.6 7.0 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 VBB33045.1 - 9.1e-09 36.0 0.0 2.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 VBB33045.1 - 1.7e-08 34.4 1.3 0.0085 16.1 0.1 3.5 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 VBB33045.1 - 2.5e-06 27.1 18.2 8.1e-05 22.2 3.4 4.5 3 2 1 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 VBB33045.1 - 0.00011 21.9 18.0 5.4 7.3 0.1 7.8 8 0 0 8 8 8 2 Leucine Rich repeat TIR PF01582.20 VBB33045.1 - 0.0028 17.5 0.2 0.0048 16.7 0.2 1.3 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 VBB33045.1 - 0.085 13.5 30.0 11 7.0 0.7 9.6 9 2 0 9 9 9 0 Leucine Rich Repeat CSTF_C PF14304.6 VBB33045.1 - 0.23 11.1 1.6 1.8 8.2 0.4 2.7 1 1 1 2 2 2 0 Transcription termination and cleavage factor C-terminal PRANC PF09372.10 VBB33045.1 - 0.9 9.9 5.9 0.28 11.5 1.0 2.7 3 0 0 3 3 3 0 PRANC domain Ku PF02735.16 VBB33046.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Oxidored_q5_N PF01059.17 VBB33046.1 - 0.15 12.1 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus VWA_2 PF13519.6 VBB33046.1 - 0.17 12.5 0.2 0.44 11.2 0.2 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain 7tm_1 PF00001.21 VBB33047.1 - 2.7e-36 125.2 10.6 3.6e-36 124.9 10.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB33047.1 - 4.1e-06 26.4 3.2 5.4e-06 26.0 3.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 VBB33047.1 - 2.1e-05 24.3 15.2 2.5e-05 24.0 15.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SplA PF11132.8 VBB33047.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) SET PF00856.28 VBB33048.1 - 2.5e-08 34.5 0.1 1.2e-07 32.3 0.1 2.0 1 1 0 1 1 1 1 SET domain DDE_Tnp_1_6 PF13751.6 VBB33048.1 - 0.009 16.2 1.2 0.016 15.5 1.2 1.4 1 0 0 1 1 1 1 Transposase DDE domain MIP PF00230.20 VBB33049.1 - 3.5e-40 138.1 10.1 4.5e-40 137.8 10.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein SH3_2 PF07653.17 VBB33050.1 - 4.1e-12 45.6 0.1 1.7e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 VBB33050.1 - 1.3e-11 43.9 0.3 6.8e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 VBB33050.1 - 1.9e-10 40.5 0.0 3.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Rrf2 PF02082.20 VBB33050.1 - 0.035 14.5 0.0 5.5 7.4 0.1 2.9 2 0 0 2 2 2 0 Transcriptional regulator DUF1043 PF06295.12 VBB33050.1 - 0.088 12.8 5.4 0.11 12.5 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Tox-REase-7 PF15649.6 VBB33050.1 - 2.8 8.3 8.6 2.1 8.7 1.6 3.5 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 7 GrpE PF01025.19 VBB33050.1 - 8 6.1 13.6 1.7 8.2 10.1 1.8 2 0 0 2 2 2 0 GrpE WD40 PF00400.32 VBB33051.1 - 2.2e-30 104.3 8.2 0.00014 22.5 0.1 9.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB33051.1 - 3.2e-13 49.8 0.0 3.9e-05 23.9 0.0 5.6 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB33051.1 - 0.0031 16.5 0.0 2.6 6.9 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 VBB33051.1 - 0.0088 15.9 0.0 53 3.6 0.0 4.3 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 VBB33051.1 - 0.0093 15.3 0.3 6.9 5.9 0.0 3.0 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 VBB33051.1 - 0.014 14.0 0.2 5.1 5.5 0.0 2.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain Methyltr_RsmB-F PF01189.17 VBB33051.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F SGL PF08450.12 VBB33051.1 - 0.074 12.6 0.7 6.3 6.3 0.1 3.7 3 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 VBB33051.1 - 0.081 12.9 5.6 5.5 7.1 0.1 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.6 VBB33051.1 - 0.21 12.2 1.3 1.4e+02 3.1 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain Solute_trans_a PF03619.16 VBB33052.1 - 9e-91 304.1 18.1 1.2e-90 303.6 18.1 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CBFB_NFYA PF02045.15 VBB33052.1 - 2.3e-26 92.2 4.6 4.1e-26 91.4 4.6 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DMAP_binding PF06464.11 VBB33053.1 - 3.9e-23 82.4 2.2 3.9e-23 82.4 2.2 2.6 1 1 3 4 4 4 1 DMAP1-binding Domain GvpG PF05120.12 VBB33053.1 - 0.00014 21.8 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Gas vesicle protein G LRR_8 PF13855.6 VBB33054.1 - 1.7e-40 136.5 55.1 1.4e-14 53.6 5.3 8.2 4 3 5 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 VBB33054.1 - 7e-26 89.9 52.6 1e-05 25.8 3.5 9.3 4 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB33054.1 - 4.7e-09 36.0 19.1 0.0009 18.8 0.4 4.7 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 VBB33054.1 - 7e-08 32.0 47.1 1.1 10.1 0.0 13.0 13 2 1 14 14 14 5 Leucine Rich Repeat LRR_5 PF13306.6 VBB33054.1 - 8.3e-08 32.2 4.5 0.0073 16.3 0.0 3.9 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 VBB33054.1 - 1.1e-07 31.3 32.6 2.2 8.6 1.4 11.9 13 0 0 13 13 13 3 Leucine Rich repeat LRR_2 PF07723.13 VBB33054.1 - 0.096 13.4 3.9 5.2 7.9 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_12 PF18837.1 VBB33054.1 - 0.35 10.6 4.9 2.6 7.8 0.0 4.5 5 0 0 5 5 5 0 Leucine-rich repeat XhlA PF10779.9 VBB33055.1 - 0.23 11.7 2.9 1 9.6 0.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA CID_GANP PF16766.5 VBB33055.1 - 0.26 11.5 2.9 11 6.3 0.0 3.7 2 1 2 4 4 4 0 Binding region of GANP to ENY2 DUF2714 PF10896.8 VBB33055.1 - 0.48 10.5 4.6 3.7 7.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2714) Jnk-SapK_ap_N PF09744.9 VBB33055.1 - 5.2 7.3 9.7 0.62 10.3 1.6 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CP2 PF04516.15 VBB33056.1 - 2e-58 197.4 0.4 2e-58 197.4 0.4 2.1 2 0 0 2 2 2 1 CP2 transcription factor DUF3413 PF11893.8 VBB33056.1 - 0.0014 17.9 1.3 0.0031 16.7 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3413) JHY PF15261.6 VBB33056.1 - 0.0014 19.4 3.3 0.0014 19.4 3.3 2.2 2 0 0 2 2 2 1 Jhy protein Ank_2 PF12796.7 VBB33057.1 - 4e-25 88.2 6.4 8.9e-11 42.2 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB33057.1 - 1.6e-21 76.4 1.7 5.4e-05 23.7 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB33057.1 - 6e-18 64.7 6.9 1.1e-05 25.5 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB33057.1 - 9.4e-18 62.5 1.3 0.00017 21.8 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 VBB33057.1 - 3e-16 59.0 5.5 2.4e-05 24.5 0.1 5.7 5 0 0 5 5 5 5 Ankyrin repeat Brix PF04427.18 VBB33058.1 - 1.8e-32 113.0 0.2 2.7e-32 112.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain LBP_BPI_CETP_C PF02886.17 VBB33059.1 - 1.3e-41 142.7 0.0 1.5e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain VWA_N2 PF16164.5 VBB33060.1 - 0.05 13.7 0.6 0.12 12.5 0.2 1.9 2 0 0 2 2 2 0 VWA N-terminal RPAP1_N PF08621.10 VBB33060.1 - 0.11 12.3 0.3 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 RPAP1-like, N-terminal Bromodomain PF00439.25 VBB33061.1 - 8.7e-108 352.6 17.7 7e-20 70.9 0.2 6.6 6 0 0 6 6 6 6 Bromodomain BAH PF01426.18 VBB33061.1 - 2.8e-14 53.0 0.1 7.1e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 BAH domain DUF4250 PF14056.6 VBB33061.1 - 3 7.9 5.0 1.6 8.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Parathyroid PF01279.17 VBB33062.1 - 0.088 13.4 1.2 0.17 12.5 1.2 1.5 1 0 0 1 1 1 0 Parathyroid hormone family Cullin PF00888.22 VBB33063.1 - 2.3e-164 548.4 12.4 2.8e-164 548.2 12.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 VBB33063.1 - 1.8e-17 63.1 1.9 6.1e-17 61.4 1.9 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Stork_head PF10264.9 VBB33063.1 - 0.0093 16.1 0.0 0.032 14.4 0.0 1.9 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain PMP22_Claudin PF00822.20 VBB33065.1 - 0.059 13.2 0.6 0.085 12.7 0.4 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family UvsW PF11637.8 VBB33066.1 - 0.021 14.9 0.1 0.021 14.9 0.1 2.5 3 0 0 3 3 3 0 ATP-dependant DNA helicase UvsW Arfaptin PF06456.13 VBB33067.1 - 5.7e-52 176.6 9.9 6.7e-52 176.3 9.9 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 VBB33067.1 - 3.9e-10 39.8 9.3 6.6e-10 39.0 9.3 1.4 1 1 0 1 1 1 1 BAR domain GPS2_interact PF15784.5 VBB33067.1 - 0.057 13.9 0.5 0.12 12.8 0.5 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain YjbH PF06082.11 VBB33067.1 - 0.13 11.0 0.7 0.18 10.6 0.3 1.4 1 1 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Lipase_GDSL PF00657.22 VBB33068.1 - 1.2e-05 25.3 0.0 3.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4604 PF15377.6 VBB33069.1 - 9.3e-09 35.9 9.2 3e-07 31.0 9.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) NYD-SP12_N PF15015.6 VBB33069.1 - 0.036 12.5 4.2 0.043 12.2 4.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DB PF01682.19 VBB33070.1 - 2.2e-23 82.4 28.0 3e-12 46.7 10.9 2.4 2 0 0 2 2 2 2 DB module fn3 PF00041.21 VBB33070.1 - 7.3e-13 48.7 1.7 9e-12 45.2 0.2 2.7 3 0 0 3 3 3 1 Fibronectin type III domain Ig_3 PF13927.6 VBB33070.1 - 1.4e-05 25.6 0.0 4.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 VBB33070.1 - 0.00015 21.7 0.0 0.00075 19.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 VBB33070.1 - 0.00016 21.8 0.0 0.00043 20.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB33070.1 - 0.00086 19.5 0.1 0.0035 17.5 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain fn3_2 PF16893.5 VBB33070.1 - 0.0018 18.4 0.1 0.0035 17.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain SusE PF14292.6 VBB33070.1 - 0.071 13.4 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 SusE outer membrane protein fn3_4 PF16794.5 VBB33070.1 - 0.17 11.8 1.0 6.6 6.7 0.3 3.4 2 2 1 3 3 3 0 Fibronectin-III type domain DUF2228 PF10228.9 VBB33071.1 - 6.6e-58 196.4 0.0 1e-57 195.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) PH_14 PF17787.1 VBB33071.1 - 0.14 12.0 0.6 7.3 6.5 0.0 2.8 3 0 0 3 3 3 0 PH domain PH_17 PF18012.1 VBB33072.1 - 2.5e-21 75.1 0.1 1e-19 70.0 0.0 2.4 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 VBB33072.1 - 6.7e-19 68.0 0.9 1.1e-18 67.3 0.9 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 VBB33072.1 - 3.3e-13 50.0 0.2 3.5e-08 33.9 0.0 2.8 2 1 0 2 2 2 2 PH domain PDZ_6 PF17820.1 VBB33072.1 - 5.2e-08 32.6 0.1 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB33072.1 - 0.00043 20.5 0.1 0.00077 19.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Fcf1 PF04900.12 VBB33073.1 - 9e-36 122.2 1.9 9e-36 122.2 1.9 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 VBB33073.1 - 1e-13 51.6 0.2 6.2e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 PIN like domain Moulting_cycle PF04870.16 VBB33073.1 - 0.04 13.2 0.2 0.041 13.2 0.2 1.2 1 0 0 1 1 1 0 Moulting cycle ETC_C1_NDUFA4 PF04800.12 VBB33074.1 - 1.2e-27 96.0 0.2 1.9e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region SSXT PF05030.12 VBB33074.1 - 1.4e-25 88.7 1.9 2.6e-25 87.8 1.9 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Hid1 PF12722.7 VBB33075.1 - 5.6e-46 157.1 0.2 6.1e-46 157.0 0.2 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 VBB33075.1 - 3e-33 115.1 0.0 3.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein BTB PF00651.31 VBB33076.1 - 1.9e-25 89.3 0.4 1.9e-25 89.3 0.4 2.3 3 0 0 3 3 3 1 BTB/POZ domain zf-H2C2_2 PF13465.6 VBB33076.1 - 3.5e-17 62.0 67.7 1.8e-05 24.9 1.0 10.4 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 VBB33076.1 - 3.4e-16 58.7 84.7 0.00057 20.2 5.3 9.8 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB33076.1 - 8.7e-13 47.9 78.1 0.032 15.1 0.5 9.9 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_5 PF13909.6 VBB33076.1 - 1.8e-11 43.6 69.6 7.4e-06 25.6 5.6 8.8 9 0 0 9 9 9 6 C2H2-type zinc-finger domain BACK PF07707.15 VBB33076.1 - 3.3e-06 27.1 0.1 8e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-Di19 PF05605.12 VBB33076.1 - 0.013 15.8 5.0 0.013 15.8 5.0 5.3 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF3342 PF11822.8 VBB33076.1 - 0.014 15.6 0.3 0.048 13.9 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Actin_micro PF17003.5 VBB33076.1 - 0.92 8.6 28.1 0.015 14.5 3.4 4.5 1 1 3 4 4 4 0 Putative actin-like family GILT PF03227.16 VBB33077.1 - 4.1e-29 101.0 0.8 5.8e-29 100.4 0.8 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) EGF PF00008.27 VBB33077.1 - 0.54 10.6 5.0 0.38 11.1 2.6 2.0 2 0 0 2 2 2 0 EGF-like domain Rho_GDI PF02115.17 VBB33078.1 - 0.068 12.9 0.7 0.079 12.7 0.7 1.1 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor eIF3_N PF09440.10 VBB33079.1 - 9.6e-36 123.2 1.5 9.6e-36 123.2 1.5 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 VBB33079.1 - 2.4e-18 66.6 2.5 5.6e-18 65.4 0.1 2.7 3 0 0 3 3 3 1 PCI domain SHNi-TPR PF10516.9 VBB33079.1 - 0.024 14.1 0.9 0.51 9.8 0.0 3.2 4 0 0 4 4 4 0 SHNi-TPR CSN8_PSD8_EIF3K PF10075.9 VBB33079.1 - 0.029 14.4 0.1 0.094 12.7 0.1 1.8 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family Takusan PF04822.13 VBB33079.1 - 1.1 9.2 6.7 0.29 11.1 0.3 2.9 3 0 0 3 3 3 0 Takusan GST_C_2 PF13410.6 VBB33080.1 - 0.013 15.5 0.1 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 VBB33080.1 - 0.08 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TspO_MBR PF03073.15 VBB33081.1 - 1.9e-14 53.9 4.6 2.3e-14 53.6 4.6 1.1 1 0 0 1 1 1 1 TspO/MBR family Fijivirus_P9-2 PF06837.11 VBB33081.1 - 0.044 13.2 1.7 0.059 12.8 1.7 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein TspO_MBR PF03073.15 VBB33082.1 - 1.2e-18 67.4 7.2 1.7e-18 67.0 7.2 1.1 1 0 0 1 1 1 1 TspO/MBR family SMN PF06003.12 VBB33083.1 - 9.3e-12 44.8 2.0 1.5e-07 30.9 0.2 2.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) TUDOR PF00567.24 VBB33083.1 - 0.00019 21.5 0.1 0.00026 21.0 0.1 1.2 1 0 0 1 1 1 1 Tudor domain SIN1 PF05422.12 VBB33083.1 - 0.059 13.9 0.0 0.079 13.5 0.0 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Coatomer_WDAD PF04053.14 VBB33084.1 - 0.00017 20.8 8.7 0.0049 16.0 0.1 3.6 2 2 0 3 3 3 2 Coatomer WD associated region Clathrin PF00637.20 VBB33084.1 - 0.00047 20.0 10.3 6.5 6.6 0.0 5.3 3 2 2 5 5 5 1 Region in Clathrin and VPS TPR_12 PF13424.6 VBB33084.1 - 0.0088 16.3 23.3 0.45 10.8 0.7 7.1 7 1 2 9 9 9 2 Tetratricopeptide repeat PPR PF01535.20 VBB33084.1 - 0.022 15.0 0.6 1.3e+02 3.1 0.1 5.1 5 1 1 6 6 6 0 PPR repeat Vps39_1 PF10366.9 VBB33084.1 - 0.18 12.1 2.1 14 6.0 0.1 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 RPN7 PF10602.9 VBB33084.1 - 0.22 11.2 5.9 2 8.1 0.6 4.0 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_1 PF00515.28 VBB33084.1 - 0.44 10.4 13.5 3.8 7.5 0.2 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33084.1 - 0.51 10.6 18.4 1.7 9.0 0.2 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF1771 PF08590.10 VBB33084.1 - 1.2 9.6 7.4 4.1 7.9 0.7 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) TPR_19 PF14559.6 VBB33084.1 - 2.5 8.7 19.8 6.6 7.3 0.4 6.2 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33084.1 - 2.7 8.4 17.0 14 6.2 0.3 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat Clathrin PF00637.20 VBB33085.1 - 3.3e-07 30.3 11.5 0.012 15.5 0.1 5.9 3 2 4 7 7 7 2 Region in Clathrin and VPS DUF410 PF04190.13 VBB33085.1 - 0.0013 18.6 3.5 0.17 11.7 0.2 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF410) TPR_7 PF13176.6 VBB33085.1 - 0.0023 17.9 13.7 1 9.6 0.0 7.1 7 1 1 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33085.1 - 0.003 17.7 0.4 0.003 17.7 0.4 4.9 6 1 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 VBB33085.1 - 0.0041 16.9 12.6 4.4 7.3 0.1 6.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 VBB33085.1 - 0.0042 17.6 3.1 3.7 8.5 0.2 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33085.1 - 0.0045 17.7 20.1 36 5.5 0.0 9.5 6 4 4 11 11 11 0 Tetratricopeptide repeat RGS PF00615.19 VBB33085.1 - 0.013 15.7 2.0 0.16 12.3 0.1 3.1 2 1 0 3 3 3 0 Regulator of G protein signaling domain SNAP PF14938.6 VBB33085.1 - 0.02 14.4 11.8 0.037 13.4 0.7 3.9 2 2 1 3 3 3 0 Soluble NSF attachment protein, SNAP VWA_3 PF13768.6 VBB33085.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain TPR_11 PF13414.6 VBB33085.1 - 0.089 12.5 4.0 34 4.2 0.1 5.2 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 VBB33085.1 - 0.15 12.3 28.3 3.1 8.1 0.1 9.0 9 3 1 11 11 10 0 Tetratricopeptide repeat MIT PF04212.18 VBB33085.1 - 0.26 11.4 2.8 53 4.0 0.0 4.5 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 VBB33085.1 - 0.62 10.6 11.5 16 6.1 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB33085.1 - 2.5 8.7 4.3 87 3.9 0.0 4.7 6 1 1 7 7 5 0 Tetratricopeptide repeat bZIP_2 PF07716.15 VBB33087.1 - 3.9e-13 49.3 14.2 3.9e-13 49.3 14.2 2.1 2 0 0 2 2 2 1 Basic region leucine zipper SUIM_assoc PF16619.5 VBB33087.1 - 0.00022 21.2 1.8 0.00022 21.2 1.8 4.3 3 1 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 bZIP_1 PF00170.21 VBB33087.1 - 0.0023 18.0 12.2 0.0032 17.5 11.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 VBB33087.1 - 2.7 8.7 7.2 0.64 10.7 2.4 2.3 1 1 2 3 3 3 0 Initiation control protein YabA SAM_decarbox PF01536.16 VBB33089.1 - 6.7e-102 341.1 0.1 8.1e-102 340.9 0.1 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TPR_19 PF14559.6 VBB33090.1 - 3.8e-05 24.1 0.0 0.0036 17.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33090.1 - 0.0036 17.4 0.1 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33090.1 - 0.046 13.9 0.0 0.24 11.6 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33090.1 - 0.069 13.4 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Astro_capsid_p PF12226.8 VBB33090.1 - 0.25 10.5 12.6 0.4 9.8 12.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TAP42 PF04177.12 VBB33090.1 - 0.33 10.0 10.6 8.4 5.4 10.6 2.1 1 1 0 1 1 1 0 TAP42-like family FAD_binding_6 PF00970.24 VBB33091.1 - 3.3e-34 117.2 0.0 4.9e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 VBB33091.1 - 7.1e-19 68.5 0.0 1.3e-11 45.1 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 VBB33091.1 - 2.3e-06 27.8 0.1 1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain eRF1_2 PF03464.15 VBB33092.1 - 3.6e-47 160.0 0.1 5.9e-47 159.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 VBB33092.1 - 1.2e-34 119.2 0.3 3.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 VBB33092.1 - 1.2e-18 67.3 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 VBB33092.1 - 1.8e-09 38.0 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 VBB33092.1 - 7.8e-09 35.9 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ank_2 PF12796.7 VBB33093.1 - 4.3e-13 49.7 0.0 2.1e-05 25.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB33093.1 - 4.5e-10 39.6 0.1 1e-05 25.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB33093.1 - 1.1e-09 38.3 0.0 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 VBB33093.1 - 3.5e-09 37.0 0.1 0.00032 21.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB33093.1 - 7.4e-09 35.2 0.0 0.0051 17.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat MIF4G_like_2 PF09090.11 VBB33095.1 - 1.7e-31 109.7 3.9 2e-31 109.5 3.9 1.1 1 0 0 1 1 1 1 MIF4G like Nucleoside_tran PF01733.18 VBB33095.1 - 0.076 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter Dynactin_p62 PF05502.13 VBB33095.1 - 0.12 11.1 0.3 0.13 11.0 0.3 1.0 1 0 0 1 1 1 0 Dynactin p62 family 3HCDH_N PF02737.18 VBB33096.1 - 1.7e-55 187.7 2.6 2.2e-55 187.3 2.6 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 VBB33096.1 - 1.3e-34 118.7 0.0 3.3e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.14 VBB33096.1 - 2.5e-06 26.9 0.2 3.5e-06 26.5 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 VBB33096.1 - 0.00021 20.7 1.0 0.00037 19.8 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 VBB33096.1 - 0.00031 21.2 0.4 0.0011 19.5 0.2 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 VBB33096.1 - 0.00058 20.1 1.3 0.00092 19.4 1.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 VBB33096.1 - 0.00069 19.6 0.3 0.0011 18.9 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 VBB33096.1 - 0.00088 18.9 1.9 0.0018 17.9 1.9 1.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 VBB33096.1 - 0.0048 16.5 0.1 0.007 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 VBB33096.1 - 0.0052 16.1 0.1 0.007 15.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 VBB33096.1 - 0.0072 16.6 1.9 0.021 15.1 1.8 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Iso_dh PF00180.20 VBB33096.1 - 0.0085 15.3 0.5 0.013 14.6 0.5 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ELFV_dehydrog PF00208.21 VBB33096.1 - 0.025 14.3 0.7 0.066 12.9 0.7 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase StbA PF06406.11 VBB33096.1 - 0.025 13.8 1.2 0.033 13.4 1.2 1.1 1 0 0 1 1 1 0 StbA protein DFP PF04127.15 VBB33096.1 - 0.044 13.6 1.4 0.1 12.4 1.3 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 VBB33096.1 - 0.045 13.4 0.2 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 VBB33096.1 - 0.049 13.9 0.4 0.098 12.9 0.4 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 VBB33096.1 - 0.053 14.0 0.3 0.097 13.1 0.3 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 VBB33096.1 - 0.066 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 VBB33096.1 - 0.12 12.6 1.1 0.33 11.2 1.1 1.7 1 1 0 1 1 1 0 TrkA-N domain MRP-S22 PF10245.9 VBB33096.1 - 0.39 10.4 5.5 0.56 9.9 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 RCC1 PF00415.18 VBB33097.1 - 5.9e-67 222.1 24.4 9e-13 48.6 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 VBB33097.1 - 1.7e-54 180.6 30.2 1.5e-11 43.8 0.6 7.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Prefoldin_2 PF01920.20 VBB33099.1 - 1.2e-19 70.2 4.5 1.5e-19 69.9 4.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit STAT_alpha PF01017.20 VBB33099.1 - 0.014 15.3 2.0 0.019 14.9 2.0 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Spc7 PF08317.11 VBB33099.1 - 0.019 13.8 3.3 0.024 13.5 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein T6PP_N PF18572.1 VBB33099.1 - 0.049 13.5 1.8 0.09 12.6 0.3 2.0 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain LPP PF04728.13 VBB33099.1 - 0.11 12.9 3.3 8.7 6.8 0.1 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper YabA PF06156.13 VBB33099.1 - 0.43 11.2 5.9 12 6.6 0.1 2.4 1 1 2 3 3 3 0 Initiation control protein YabA XhlA PF10779.9 VBB33099.1 - 1.4 9.2 7.1 2.7 8.3 0.7 2.4 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.21 VBB33099.1 - 2.8 8.1 7.0 9.3 6.4 0.8 2.4 2 1 0 2 2 2 0 bZIP transcription factor Spc24 PF08286.11 VBB33099.1 - 3.2 8.0 9.7 8.1e+02 0.3 9.7 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Clathrin_lg_ch PF01086.17 VBB33100.1 - 5.1e-10 39.8 0.0 7.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Clathrin light chain C1_1 PF00130.22 VBB33101.1 - 8.9e-13 47.9 5.6 8.9e-13 47.9 5.6 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_6 PF13405.6 VBB33101.1 - 1.5e-10 40.2 0.1 2.5e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 VBB33101.1 - 6.3e-10 37.9 0.6 0.00015 21.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 VBB33101.1 - 8.3e-10 37.7 6.2 9e-05 21.8 0.0 3.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 VBB33101.1 - 1.1e-08 35.3 0.6 0.00082 19.8 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB33101.1 - 0.00085 19.1 0.1 1.6 8.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB33101.1 - 0.018 15.4 0.0 0.12 12.7 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PINIT PF14324.6 VBB33101.1 - 0.097 13.0 0.3 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 PINIT domain DUF2102 PF09875.9 VBB33101.1 - 1.4 8.6 7.7 2.6 7.8 1.1 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2102) SAM_1 PF00536.30 VBB33102.1 - 9.2e-28 96.5 0.0 7.7e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 VBB33102.1 - 1.8e-22 79.2 0.0 1.7e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Caskin-tail PF16632.5 VBB33102.1 - 4.3e-07 30.2 3.6 3.1e-06 27.5 0.1 3.0 3 0 0 3 3 3 1 C-terminal region of Caskin Ku PF02735.16 VBB33103.1 - 1.5e-19 70.5 0.0 2.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 VBB33103.1 - 1e-07 32.5 0.4 1.6e-07 31.9 0.4 1.3 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm EF-hand_7 PF13499.6 VBB33104.1 - 5.7e-08 33.1 12.4 8.5e-06 26.1 0.9 3.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 VBB33104.1 - 7.8e-08 31.7 4.0 0.022 14.7 0.2 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_13 PF17958.1 VBB33104.1 - 3.7e-05 23.5 0.1 0.0014 18.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 VBB33104.1 - 4.7e-05 22.6 4.3 0.017 14.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 VBB33104.1 - 0.00011 21.5 0.4 0.45 10.1 0.1 2.9 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 VBB33104.1 - 0.014 15.7 1.7 2.2 8.6 0.1 2.8 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CK2S PF15011.6 VBB33104.1 - 0.077 12.9 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate EF-hand_8 PF13833.6 VBB33104.1 - 0.34 10.8 3.3 1.7 8.6 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair RRS1 PF04939.12 VBB33105.1 - 1.1e-50 171.6 8.5 1.1e-50 171.6 8.5 2.2 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) GILT PF03227.16 VBB33106.1 - 7.6e-23 80.8 2.7 7.6e-23 80.8 2.7 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Vps39_2 PF10367.9 VBB33106.1 - 0.52 10.8 3.7 0.67 10.4 0.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Pkinase_Tyr PF07714.17 VBB33108.1 - 3.4e-79 265.8 0.2 4.3e-79 265.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB33108.1 - 1.1e-46 159.4 0.1 1.4e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 VBB33108.1 - 2.3e-10 40.4 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.14 VBB33108.1 - 0.027 13.8 0.7 0.041 13.2 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CP_ATPgrasp_1 PF04174.13 VBB33108.1 - 0.03 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Bac_chlorC PF02043.17 VBB33108.1 - 0.097 12.7 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein CD4-extracel PF09191.10 VBB33109.1 - 0.035 14.5 0.2 0.041 14.3 0.2 1.1 1 0 0 1 1 1 0 CD4, extracellular Laminin_N PF00055.17 VBB33110.1 - 2.9e-83 279.0 0.0 2.9e-83 279.0 0.0 2.5 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 VBB33110.1 - 4.4e-58 193.2 181.4 3.1e-11 43.2 12.0 10.4 11 0 0 11 11 11 9 Laminin EGF domain Laminin_B PF00052.18 VBB33110.1 - 6.2e-23 81.2 0.0 9e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) UPF0564 PF10595.9 VBB33111.1 - 4e-14 52.5 39.5 4e-14 52.5 39.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 Myosin-VI_CBD PF16521.5 VBB33112.1 - 4.1e-40 135.7 0.1 4.1e-40 135.7 0.1 2.1 2 1 0 2 2 2 1 Myosin VI cargo binding domain Herpes_capsid PF06112.11 VBB33112.1 - 0.95 9.5 5.6 1.7 8.7 5.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CTNNBL PF08216.11 VBB33113.1 - 9.7e-35 118.9 1.2 3.3e-34 117.2 1.2 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear TFCD_C PF12612.8 VBB33113.1 - 1.1e-33 116.7 1.8 1e-31 110.2 0.6 3.0 2 0 0 2 2 2 2 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 VBB33113.1 - 0.22 11.9 2.4 2 8.9 0.2 3.5 3 0 0 3 3 3 0 HEAT repeats Cnd1 PF12717.7 VBB33113.1 - 0.87 9.6 9.6 4.4 7.3 0.1 4.8 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Kinesin PF00225.23 VBB33114.1 - 0.0033 16.4 0.0 0.0033 16.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Tubulin PF00091.25 VBB33116.1 - 6.5e-52 176.6 0.1 7.1e-52 176.5 0.1 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 VBB33116.1 - 1e-06 29.0 0.0 1.5e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain COX15-CtaA PF02628.15 VBB33117.1 - 2.4e-89 299.6 17.3 6.3e-88 295.0 10.6 2.1 2 0 0 2 2 2 2 Cytochrome oxidase assembly protein Cyto_heme_lyase PF01265.17 VBB33117.1 - 7e-65 219.5 12.0 3.8e-64 217.1 12.0 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase N6_Mtase PF02384.16 VBB33117.1 - 2.3 7.4 4.0 0.62 9.3 0.1 2.1 3 0 0 3 3 3 0 N-6 DNA Methylase WCCH PF03716.14 VBB33117.1 - 3 7.6 7.5 2.8 7.7 1.3 2.6 2 0 0 2 2 2 0 WCCH motif Sec10 PF07393.11 VBB33119.1 - 1.4e-138 463.5 18.5 7.7e-135 451.0 15.8 3.7 1 1 1 2 2 2 1 Exocyst complex component Sec10 FAM184 PF15665.5 VBB33119.1 - 0.16 11.7 6.8 0.049 13.4 2.3 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B APP_E2 PF12925.7 VBB33119.1 - 0.17 11.6 5.1 0.43 10.3 3.9 2.3 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein Patched PF02460.18 VBB33120.1 - 5.8e-57 193.4 0.0 7.1e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Patched family Oxysterol_BP PF01237.18 VBB33121.1 - 9.8e-137 455.7 0.5 1.6e-136 455.0 0.5 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 VBB33121.1 - 1.3e-13 51.0 0.1 3e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 VBB33121.1 - 1.2e-11 45.1 0.5 4.4e-11 43.2 0.5 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 VBB33121.1 - 0.001 19.4 5.8 0.0021 18.4 2.4 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain NAD_binding_1 PF00175.21 VBB33121.1 - 0.13 12.9 0.7 0.99 10.1 0.2 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ank_2 PF12796.7 VBB33122.1 - 5.6e-29 100.6 0.5 5.9e-17 62.0 0.5 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 VBB33122.1 - 7.2e-25 86.3 8.4 2.8e-08 33.8 0.3 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 VBB33122.1 - 5.4e-24 83.9 11.1 1.3e-10 41.3 1.1 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 VBB33122.1 - 1.1e-21 76.9 10.7 2.1e-10 40.9 0.2 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB33122.1 - 5.3e-20 69.4 5.2 1.3e-05 25.2 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Imm49 PF15575.6 VBB33122.1 - 0.042 13.6 4.8 0.21 11.3 0.2 2.9 4 0 0 4 4 4 0 Immunity protein 49 DUF1768 PF08719.11 VBB33123.1 - 9.1e-28 97.5 0.8 3e-16 60.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) Annexin PF00191.20 VBB33123.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Annexin P21-Arc PF04062.14 VBB33124.1 - 0.12 12.4 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 ARP2/3 complex ARPC3 (21 kDa) subunit Costars PF14705.6 VBB33125.1 - 1.7e-25 88.9 0.0 4.1e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Costars TUDOR PF00567.24 VBB33125.1 - 1.2e-16 60.8 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Tudor domain DUF5072 PF16807.5 VBB33125.1 - 0.1 12.6 0.1 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) DMAP1 PF05499.12 VBB33125.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) zf-MYND PF01753.18 VBB33126.1 - 1.6e-10 40.9 8.4 1.6e-10 40.9 8.4 3.5 2 1 1 3 3 3 1 MYND finger TPR_12 PF13424.6 VBB33126.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TERF2_RBM PF16772.5 VBB33126.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif NPDC1 PF06809.11 VBB33128.1 - 3.2e-15 56.0 0.0 4.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) DUF2781 PF10914.8 VBB33129.1 - 0.035 14.5 0.2 0.038 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Hexokinase_1 PF00349.21 VBB33130.1 - 1.6e-52 178.3 0.0 2.2e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 VBB33130.1 - 3.2e-51 174.1 0.4 2e-48 164.9 1.0 2.6 2 1 0 2 2 2 1 Hexokinase WD40_4 PF16300.5 VBB33131.1 - 7.2e-16 57.8 0.1 1.2e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 VBB33131.1 - 1.6e-08 35.0 2.6 0.00017 22.3 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1899 PF08953.11 VBB33131.1 - 1.5e-06 27.9 0.2 5.3e-06 26.2 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1899) PQQ_2 PF13360.6 VBB33131.1 - 0.0011 18.6 0.0 0.094 12.3 0.0 2.3 1 1 1 2 2 2 1 PQQ-like domain eIF2A PF08662.11 VBB33131.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 VBB33131.1 - 0.0084 16.4 4.1 0.063 13.6 0.2 3.5 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 VBB33131.1 - 0.013 14.4 0.0 0.037 13.0 0.0 1.8 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SlyX PF04102.12 VBB33131.1 - 8.1 7.1 7.4 1.1 10.0 2.6 2.0 2 0 0 2 2 2 0 SlyX 7tm_1 PF00001.21 VBB33132.1 - 6.6e-38 130.5 6.5 8.6e-38 130.2 6.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB33132.1 - 1.1e-05 25.0 2.6 1.5e-05 24.5 2.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 VBB33132.1 - 0.0042 16.6 4.4 0.0056 16.2 4.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc Phage_holin_3_6 PF07332.11 VBB33132.1 - 4 7.5 9.0 0.39 10.8 3.7 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Cwf_Cwc_15 PF04889.12 VBB33133.1 - 0.071 12.8 10.4 0.08 12.7 10.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ELH PF02323.15 VBB33133.1 - 0.1 11.9 4.2 0.1 11.9 4.2 1.0 1 0 0 1 1 1 0 Egg-laying hormone precursor CENP-B_dimeris PF09026.10 VBB33133.1 - 0.13 12.7 15.9 0.16 12.4 15.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 VBB33133.1 - 0.86 8.9 11.6 0.96 8.7 11.6 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 VBB33133.1 - 1 8.4 11.2 1.1 8.3 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.8 VBB33133.1 - 8.2 5.5 11.7 9 5.3 11.7 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3295 PF11702.8 VBB33133.1 - 9.1 5.5 10.6 9.4 5.5 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pou PF00157.17 VBB33134.1 - 3.3e-37 126.3 0.1 8.4e-37 125.0 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 VBB33134.1 - 8.4e-13 48.0 3.2 1.3e-12 47.3 1.6 2.3 2 0 0 2 2 2 1 Homeodomain Spt20 PF12090.8 VBB33134.1 - 7.5e-05 22.4 43.7 0.0049 16.5 24.5 2.5 2 0 0 2 2 2 2 Spt20 family HTH_31 PF13560.6 VBB33134.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain EPL1 PF10513.9 VBB33134.1 - 0.37 11.2 25.6 0.37 11.2 10.0 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like Calc_CGRP_IAPP PF00214.19 VBB33134.1 - 0.68 10.3 6.0 0.49 10.8 0.3 2.6 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Forkhead PF00250.18 VBB33135.1 - 8.1e-13 48.4 0.0 1.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain G_path_suppress PF15991.5 VBB33135.1 - 0.19 11.9 1.3 0.3 11.2 1.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor PDZ PF00595.24 VBB33137.1 - 1.8e-11 44.2 0.0 3.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB33137.1 - 7.4e-11 41.7 0.0 2.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB33137.1 - 5.1e-06 26.7 0.0 1.5e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PPS_PS PF02006.16 VBB33137.1 - 0.038 13.5 0.3 0.072 12.6 0.3 1.4 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Tricorn_PDZ PF14685.6 VBB33137.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Mucin PF01456.17 VBB33137.1 - 0.21 11.6 13.6 0.55 10.2 13.6 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 VBB33137.1 - 0.46 10.5 12.1 1.2 9.1 12.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UCH PF00443.29 VBB33139.1 - 9.3e-10 38.4 18.8 3.5e-08 33.3 16.1 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.16 VBB33140.1 - 4.2e-42 144.3 30.9 3.4e-39 134.8 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB33140.1 - 1.6e-07 30.6 9.3 1.6e-07 30.6 9.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF872 PF05915.12 VBB33140.1 - 2.5 8.3 7.6 16 5.7 0.1 4.1 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) THUMP PF02926.17 VBB33141.1 - 3.2e-09 37.0 0.2 9.9e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 THUMP domain Pho88 PF10032.9 VBB33141.1 - 0.097 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphate transport (Pho88) Reprolysin PF01421.19 VBB33142.1 - 5.7e-14 52.5 0.0 1.2e-13 51.5 0.0 1.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 VBB33142.1 - 1.6e-09 38.2 0.1 2.9e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.19 VBB33142.1 - 5.6e-09 36.4 0.1 9.4e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.6 VBB33142.1 - 1.2e-05 25.9 0.2 2.4e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 VBB33142.1 - 0.00058 20.3 0.1 0.0013 19.2 0.1 1.6 1 0 0 1 1 1 1 ADAM cysteine-rich domain Peptidase_M57 PF12388.8 VBB33142.1 - 0.0034 17.0 0.2 0.0058 16.3 0.2 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 VBB33142.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 VBB33142.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DNTTIP1_dimer PF18192.1 VBB33142.1 - 0.097 13.0 0.4 2.1 8.8 0.0 3.0 3 1 0 3 3 3 0 DNTTIP1 dimerisation domain LptD PF04453.14 VBB33142.1 - 0.21 10.8 0.2 0.88 8.7 0.0 1.9 2 0 0 2 2 2 0 LPS transport system D Ion_trans PF00520.31 VBB33143.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 VBB33144.1 - 1.4e-52 178.4 10.9 1.5e-52 178.3 10.9 1.0 1 0 0 1 1 1 1 Ion transport protein DSL PF01414.19 VBB33144.1 - 0.096 13.0 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Delta serrate ligand PKD_channel PF08016.12 VBB33144.1 - 0.12 11.0 0.1 0.12 11.0 0.1 2.9 2 1 1 3 3 3 0 Polycystin cation channel Ldl_recept_a PF00057.18 VBB33145.1 - 2.2e-18 66.2 59.2 1.1e-05 25.5 7.3 6.9 3 1 3 6 6 6 4 Low-density lipoprotein receptor domain class A EGF_CA PF07645.15 VBB33145.1 - 1e-08 35.2 18.6 6.6e-06 26.2 5.5 8.1 7 2 0 7 7 7 3 Calcium-binding EGF domain EGF PF00008.27 VBB33145.1 - 2.4e-06 27.7 15.5 2.2e-05 24.6 4.2 7.4 6 1 0 6 6 6 2 EGF-like domain EGF_3 PF12947.7 VBB33145.1 - 1.7e-05 24.9 15.8 0.00087 19.4 4.9 6.4 5 1 0 5 5 5 3 EGF domain EGF_MSP1_1 PF12946.7 VBB33145.1 - 7.6e-05 22.7 12.4 0.00055 19.9 2.0 5.3 4 1 0 4 4 4 2 MSP1 EGF domain 1 hEGF PF12661.7 VBB33145.1 - 0.00053 20.5 10.3 0.0024 18.5 1.8 8.1 6 1 0 6 6 6 2 Human growth factor-like EGF CBM_14 PF01607.24 VBB33147.1 - 6.5e-14 51.8 18.5 7e-07 29.3 4.0 2.6 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain WAP PF00095.21 VBB33147.1 - 0.83 10.1 0.1 0.83 10.1 0.1 3.6 4 1 0 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Brr6_like_C_C PF10104.9 VBB33147.1 - 4.2 7.1 5.7 5.3 6.8 0.1 2.9 2 2 1 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain SHMT PF00464.19 VBB33148.1 - 2.6e-189 628.9 0.0 3.1e-189 628.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 VBB33148.1 - 0.0059 15.8 0.0 0.0099 15.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II UCH PF00443.29 VBB33149.1 - 6.5e-68 229.0 0.0 1e-67 228.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB33149.1 - 4e-14 53.0 3.8 2.1e-07 30.8 0.7 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 VBB33149.1 - 2e-10 41.2 0.7 9.1e-10 39.0 0.7 2.1 2 0 0 2 2 2 1 DUSP domain EF-hand_6 PF13405.6 VBB33149.1 - 1.7e-08 33.7 1.8 0.0027 17.5 0.1 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 VBB33149.1 - 1.2e-07 30.8 4.1 0.0063 16.0 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 VBB33149.1 - 6.4e-07 29.7 1.6 0.016 15.7 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB33149.1 - 8.1e-07 28.8 2.6 0.02 14.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB33149.1 - 6.6e-06 25.4 3.3 0.039 13.5 1.0 2.9 2 0 0 2 2 2 2 EF hand RGS_DHEX PF18148.1 VBB33150.1 - 5.1e-25 87.5 0.2 8.2e-25 86.8 0.2 1.4 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain DEP PF00610.21 VBB33150.1 - 5.5e-12 45.6 0.0 3.5e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Neur_chan_memb PF02932.16 VBB33151.1 - 5e-68 229.7 13.5 4.1e-66 223.5 13.5 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 VBB33151.1 - 5e-11 42.5 0.0 6.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Claudin_2 PF13903.6 VBB33151.1 - 0.088 12.6 2.7 0.12 12.1 2.0 1.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.9 VBB33151.1 - 2.1 7.7 11.0 3.4 7.0 9.1 2.0 2 1 0 2 2 2 0 Region of unknown function (DUF2417) Pkinase PF00069.25 VBB33152.1 - 2e-61 207.7 0.3 7.7e-61 205.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33152.1 - 6e-39 133.9 0.0 1.4e-38 132.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB33152.1 - 0.08 12.8 0.0 0.08 12.8 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.29 VBB33153.1 - 7.9e-44 149.3 0.2 2.6e-43 147.6 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB33153.1 - 3.4e-12 46.0 0.1 7.9e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 VBB33153.1 - 7.9e-08 32.6 0.8 4.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 VBB33153.1 - 1e-06 28.8 0.0 4e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 VBB33153.1 - 1.2e-06 28.4 0.2 3.3e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 VBB33153.1 - 2.5e-06 28.0 0.1 4.8e-05 23.8 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 VBB33153.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB33153.1 - 0.00011 22.5 2.9 0.013 15.8 0.1 2.8 2 1 1 3 3 3 1 AAA domain DUF1090 PF06476.12 VBB33153.1 - 0.00074 19.6 3.8 0.014 15.5 1.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1090) APG6_N PF17675.1 VBB33153.1 - 0.0011 19.5 1.9 0.0023 18.5 1.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region AAA_33 PF13671.6 VBB33153.1 - 0.0013 19.0 0.4 0.0032 17.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain Filament PF00038.21 VBB33153.1 - 0.0015 18.1 4.9 0.0027 17.3 4.9 1.3 1 0 0 1 1 1 1 Intermediate filament protein IstB_IS21 PF01695.17 VBB33153.1 - 0.0018 18.0 0.3 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 VBB33153.1 - 0.002 17.4 0.0 0.0053 16.0 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain MscS_porin PF12795.7 VBB33153.1 - 0.003 17.1 3.3 0.0049 16.4 3.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain AAA_18 PF13238.6 VBB33153.1 - 0.0032 18.0 0.1 0.015 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 VBB33153.1 - 0.0068 15.8 0.5 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 VBB33153.1 - 0.0077 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 VBB33153.1 - 0.0086 15.9 2.4 0.39 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 VBB33153.1 - 0.0088 15.9 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 VBB33153.1 - 0.01 15.3 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF2072 PF09845.9 VBB33153.1 - 0.011 16.0 3.3 0.022 15.0 3.3 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Prominin PF05478.11 VBB33153.1 - 0.015 13.3 1.0 0.021 12.8 1.0 1.1 1 0 0 1 1 1 0 Prominin AAA_28 PF13521.6 VBB33153.1 - 0.017 15.4 0.7 0.034 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 VBB33153.1 - 0.022 14.5 0.1 0.065 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 VBB33153.1 - 0.023 14.4 0.1 0.12 12.0 0.0 2.2 2 1 1 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 VBB33153.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Spc7 PF08317.11 VBB33153.1 - 0.038 12.9 4.0 0.069 12.0 4.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF815 PF05673.13 VBB33153.1 - 0.041 13.0 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 VBB33153.1 - 0.043 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 VBB33153.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 VBB33153.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 VBB33153.1 - 0.051 13.1 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain GAS PF13851.6 VBB33153.1 - 0.062 12.6 10.9 0.32 10.3 7.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Parvo_NS1 PF01057.17 VBB33153.1 - 0.064 12.3 0.4 0.11 11.5 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 VBB33153.1 - 0.081 13.4 0.5 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 VBB33153.1 - 0.11 11.8 1.2 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 VBB33153.1 - 0.12 12.7 0.2 0.28 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain SKI PF01202.22 VBB33153.1 - 0.12 12.5 1.2 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase V_ATPase_I PF01496.19 VBB33153.1 - 0.17 9.8 1.6 0.26 9.2 1.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 VBB33153.1 - 0.18 12.4 2.5 0.59 10.8 2.5 1.9 1 0 0 1 1 1 0 SlyX AAA_17 PF13207.6 VBB33153.1 - 0.2 12.1 2.1 0.64 10.4 0.0 2.7 3 1 0 3 3 2 0 AAA domain Atg14 PF10186.9 VBB33153.1 - 0.22 10.6 2.2 0.33 10.0 2.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RILP PF11461.8 VBB33153.1 - 0.24 11.7 4.9 0.32 11.3 3.8 1.8 1 1 0 1 1 1 0 Rab interacting lysosomal protein DivIC PF04977.15 VBB33153.1 - 0.24 11.2 2.3 0.62 9.9 2.3 1.7 1 0 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.10 VBB33153.1 - 0.29 11.3 2.8 0.76 10.0 2.8 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 VBB33153.1 - 0.41 10.2 5.7 0.65 9.5 5.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 VBB33153.1 - 0.71 10.4 3.4 4 8.0 1.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 VBB33153.1 - 0.77 9.8 5.6 3.6 7.6 3.1 2.7 3 0 0 3 3 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 VBB33153.1 - 2.1 9.0 4.9 2 9.0 0.8 2.7 4 0 0 4 4 2 0 Syntaxin 6, N-terminal V-SNARE PF05008.15 VBB33153.1 - 2.5 8.5 8.7 0.91 9.9 1.4 2.9 2 1 1 3 3 2 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.11 VBB33153.1 - 2.6 8.5 6.4 3.2 8.2 3.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 VBB33153.1 - 3.5 7.7 6.3 2 8.4 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FAO_M PF16350.5 VBB33154.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase central domain zf-C2HC5 PF06221.13 VBB33155.1 - 2.5 8.2 11.4 0.45 10.5 0.4 3.4 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type Sugar_tr PF00083.24 VBB33156.1 - 2.8e-44 151.7 16.3 3.9e-44 151.3 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB33156.1 - 1.2e-26 93.4 33.0 5.2e-18 65.1 16.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 VBB33156.1 - 0.0042 16.4 18.2 0.15 11.4 4.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB HEAT PF02985.22 VBB33158.1 - 2.5e-08 33.5 2.9 0.0012 18.9 0.0 4.1 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.8 VBB33158.1 - 9.7e-07 28.6 0.1 1.8e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 VBB33158.1 - 7.7e-05 23.0 1.1 0.011 16.1 0.2 2.9 1 1 3 4 4 4 4 HEAT repeats Cnd1 PF12717.7 VBB33158.1 - 0.00035 20.6 0.4 1.5 8.9 0.0 2.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 VBB33158.1 - 0.00091 19.7 2.7 1.4 9.5 0.3 3.0 3 0 0 3 3 3 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 VBB33158.1 - 0.0016 19.0 0.1 0.49 11.0 0.1 2.2 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 VBB33158.1 - 0.0064 16.5 0.1 0.044 13.9 0.0 2.3 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 VBB33158.1 - 0.0081 16.4 1.2 0.097 13.0 0.0 2.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.12 VBB33158.1 - 0.031 14.0 2.3 0.13 12.0 0.8 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 VBB33158.1 - 0.049 13.5 0.1 0.092 12.6 0.1 1.4 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RasGEF_N_2 PF14663.6 VBB33158.1 - 0.13 12.7 1.7 9.3 6.7 0.1 3.2 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Annexin PF00191.20 VBB33159.1 - 0.00013 22.0 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Annexin DUF273 PF03314.14 VBB33160.1 - 1.6e-43 148.8 11.8 1.7e-27 96.4 4.1 2.4 1 1 1 2 2 2 2 Protein of unknown function, DUF273 GRIM-19 PF06212.12 VBB33160.1 - 0.034 14.1 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 GRIM-19 protein APG6_N PF17675.1 VBB33161.1 - 0.00083 19.9 13.6 0.00083 19.9 13.6 2.1 1 1 1 2 2 2 1 Apg6 coiled-coil region BRE1 PF08647.11 VBB33161.1 - 0.059 13.4 25.8 0.35 11.0 4.8 3.4 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Phage_capsid PF05065.13 VBB33161.1 - 0.1 11.9 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Phage capsid family DUF2203 PF09969.9 VBB33161.1 - 0.36 11.6 14.4 0.37 11.5 9.5 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) GAS PF13851.6 VBB33161.1 - 1 8.7 31.6 0.093 12.1 9.2 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 VBB33161.1 - 1.4 9.0 24.8 3.8 7.7 3.3 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 LMBR1 PF04791.16 VBB33161.1 - 1.6 7.5 10.4 2.1 7.2 10.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2730 PF10805.8 VBB33161.1 - 4.4 7.4 14.5 0.48 10.6 1.4 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) FliJ PF02050.16 VBB33161.1 - 4.6 7.5 23.7 11 6.3 0.3 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein Cluap1 PF10234.9 VBB33161.1 - 6.5 6.1 24.5 2.3 7.6 19.7 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4407 PF14362.6 VBB33161.1 - 8.3 5.7 14.6 0.71 9.2 5.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ras PF00071.22 VBB33162.1 - 3.6e-42 143.7 0.0 4.5e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB33162.1 - 1.3e-18 67.4 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB33162.1 - 1.4e-07 31.2 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 VBB33162.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB33162.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 VBB33162.1 - 0.08 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AMP-binding PF00501.28 VBB33164.1 - 6.5e-68 229.3 0.0 7.3e-55 186.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Guanylate_cyc PF00211.20 VBB33165.1 - 3e-70 235.6 0.3 1.6e-69 233.2 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 VBB33165.1 - 2.5e-33 115.5 0.0 4.6e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB33165.1 - 2e-31 109.4 0.0 3.8e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 VBB33165.1 - 0.0027 17.2 1.0 0.0027 17.2 1.0 1.8 2 0 0 2 2 2 1 Heme NO binding associated Methyltransf_16 PF10294.9 VBB33166.1 - 8.9e-26 90.7 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 VBB33166.1 - 0.00042 19.9 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DegV PF02645.16 VBB33166.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 COMM_domain PF07258.14 VBB33168.1 - 0.0049 16.9 0.9 0.031 14.4 0.1 2.4 2 1 0 2 2 2 1 COMM domain SH2 PF00017.24 VBB33169.1 - 4.4e-26 90.8 0.1 7.7e-26 90.0 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 VBB33169.1 - 8.8e-15 54.0 0.1 2.1e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB33169.1 - 7.1e-12 45.0 0.1 1.8e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 VBB33169.1 - 6.8e-11 41.7 0.0 3e-09 36.4 0.0 2.5 2 1 0 2 2 2 1 Variant SH3 domain DUF707 PF05212.12 VBB33169.1 - 0.0078 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF707) Ribosomal_L24e PF01246.20 VBB33170.1 - 3.8e-14 52.7 5.3 8.5e-14 51.5 5.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Defensin_big PF14862.6 VBB33170.1 - 0.35 11.2 2.3 0.67 10.3 2.3 1.4 1 0 0 1 1 1 0 Big defensin Keratin_assoc PF09775.9 VBB33171.1 - 5.7e-39 132.7 13.6 6.3e-39 132.6 13.6 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 Herpes_LMP1 PF05297.11 VBB33171.1 - 8.1 5.5 5.2 9.1 5.4 5.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Myosin_head PF00063.21 VBB33172.1 - 2.8e-145 485.2 0.0 3.5e-145 484.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) LRR_8 PF13855.6 VBB33172.1 - 4.6e-16 58.3 21.8 2.5e-10 40.0 4.7 4.2 1 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 VBB33172.1 - 2.4e-12 46.9 30.6 2.9e-06 27.5 1.7 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) Myosin_N PF02736.19 VBB33172.1 - 0.00023 20.9 0.3 0.00049 19.9 0.3 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 VBB33172.1 - 0.00047 20.4 0.2 0.0017 18.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB33172.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain LRR_1 PF00560.33 VBB33172.1 - 0.81 10.5 33.8 2.3 9.1 0.2 7.9 8 0 0 8 8 8 0 Leucine Rich Repeat MyTH4 PF00784.17 VBB33173.1 - 1.5e-25 89.8 0.0 1.5e-25 89.8 0.0 2.4 2 1 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 VBB33173.1 - 1.7e-10 41.3 0.0 2.9e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 FERM central domain RA PF00788.23 VBB33173.1 - 4.5e-05 24.0 0.3 0.00013 22.5 0.3 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 VBB33173.1 - 0.0019 18.5 2.2 0.018 15.3 0.3 2.5 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Endonuclea_NS_2 PF13930.6 VBB33174.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Cyclin_C_2 PF16899.5 VBB33175.1 - 2.5e-17 63.1 0.5 1.6e-15 57.3 0.1 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 VBB33175.1 - 1.8e-07 30.9 1.0 7.1e-07 29.0 0.3 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 VBB33175.1 - 0.00067 19.7 0.2 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 VBB33175.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIIB repeat UPF0561 PF10573.9 VBB33176.1 - 0.39 10.9 5.8 0.52 10.4 2.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF4592 PF15262.6 VBB33176.1 - 1.1 10.0 10.6 0.31 11.7 6.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) Globin PF00042.22 VBB33177.1 - 0.0073 16.9 0.2 0.02 15.4 0.0 1.9 2 1 0 2 2 2 1 Globin VAPB_antitox PF02697.14 VBB33177.1 - 0.012 16.4 2.2 0.015 16.1 0.7 2.0 2 0 0 2 2 2 0 Putative antitoxin Med2 PF11214.8 VBB33177.1 - 0.016 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 Mediator complex subunit 2 CHD5 PF04420.14 VBB33178.1 - 2e-07 31.0 0.1 2.3e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein PUMA PF15826.5 VBB33180.1 - 0.044 14.0 0.0 0.054 13.7 0.0 1.1 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis EGF_CA PF07645.15 VBB33181.1 - 1.3e-17 63.7 34.1 1.6e-07 31.4 2.9 4.2 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_3 PF12947.7 VBB33181.1 - 3.7e-11 43.0 36.4 7e-05 22.9 8.0 4.6 4 1 0 4 4 4 4 EGF domain hEGF PF12661.7 VBB33181.1 - 2.4e-10 40.6 33.5 4.8e-06 27.0 1.7 5.7 6 1 0 6 6 6 3 Human growth factor-like EGF EGF PF00008.27 VBB33181.1 - 7.1e-10 39.0 33.3 7.7e-05 22.9 2.6 5.0 6 0 0 6 6 6 4 EGF-like domain Plasmod_Pvs28 PF06247.11 VBB33181.1 - 1.5e-08 34.8 23.4 3.6e-05 24.0 3.1 4.6 4 1 0 4 4 4 2 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 VBB33181.1 - 3.8e-05 23.6 30.3 0.0019 18.2 2.8 4.6 5 0 0 5 5 5 2 MSP1 EGF domain 1 FXa_inhibition PF14670.6 VBB33181.1 - 0.00024 21.3 26.6 0.0082 16.4 2.0 4.5 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB33181.1 - 0.00096 19.0 2.7 0.038 13.9 0.2 5.0 5 1 0 5 5 5 3 Complement Clr-like EGF-like S_locus_glycop PF00954.20 VBB33181.1 - 0.028 14.9 12.0 0.043 14.3 1.2 2.5 2 0 0 2 2 2 0 S-locus glycoprotein domain IRK_C PF17655.1 VBB33183.1 - 2.9e-72 241.9 0.0 5e-72 241.2 0.0 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 VBB33183.1 - 2.8e-08 33.7 2.4 8.8e-07 28.8 0.9 2.3 1 1 1 2 2 2 2 Inward rectifier potassium channel transmembrane domain PRIMA1 PF16101.5 VBB33184.1 - 0.083 12.9 5.2 0.063 13.3 2.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 VBB33184.1 - 2.5 7.6 11.0 0.19 11.3 5.9 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal Ran_BP1 PF00638.18 VBB33185.1 - 8.5e-12 45.4 0.1 3.1e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 VBB33185.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 WH1 domain fn3 PF00041.21 VBB33186.1 - 7.9e-108 353.0 43.7 9.4e-13 48.3 0.5 13.6 13 1 0 13 13 13 11 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB33186.1 - 9.7e-36 122.2 18.2 0.00029 21.4 0.0 12.2 11 1 0 11 11 11 9 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 VBB33186.1 - 7.5e-14 51.9 0.1 15 6.0 0.0 10.2 11 0 0 11 11 11 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 VBB33186.1 - 4.2e-08 33.5 0.0 0.44 11.0 0.0 7.0 7 1 0 7 7 7 1 Uncharacterised conserved protein (DUF2369) Glyco_hydro_36C PF16874.5 VBB33186.1 - 1.9e-05 25.1 0.0 32 5.1 0.0 6.9 9 0 0 9 9 9 0 Glycosyl hydrolase family 36 C-terminal domain Tissue_fac PF01108.17 VBB33186.1 - 4e-05 23.4 9.4 0.092 12.6 1.4 6.3 7 2 0 7 7 7 2 Tissue factor fn3_2 PF16893.5 VBB33186.1 - 0.00029 20.9 0.7 6.1 7.1 0.0 5.9 7 0 0 7 7 7 1 Fibronectin type III domain PhoD_N PF16655.5 VBB33186.1 - 0.00095 19.7 0.4 0.4 11.2 0.0 4.8 5 0 0 5 5 5 1 PhoD-like phosphatase, N-terminal domain Arylsulfotran_N PF17425.2 VBB33186.1 - 0.0055 16.7 0.0 0.98 9.5 0.0 4.4 5 0 0 5 5 5 1 Arylsulfotransferase Ig-like domain CBM_4_9 PF02018.17 VBB33186.1 - 0.058 13.7 3.4 5 7.4 0.0 5.4 6 1 0 6 6 6 0 Carbohydrate binding domain LSM PF01423.22 VBB33187.1 - 2.1e-17 62.5 0.3 2.5e-17 62.3 0.3 1.1 1 0 0 1 1 1 1 LSM domain RRM_1 PF00076.22 VBB33188.1 - 6.3e-38 128.4 0.2 3.7e-19 68.3 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB33188.1 - 1e-18 67.2 0.3 7.5e-10 38.8 0.0 2.7 1 1 1 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB33188.1 - 2.5e-08 33.8 0.3 0.00011 22.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 VBB33188.1 - 0.002 18.1 0.9 0.18 11.9 0.2 2.3 1 1 1 2 2 2 2 RNA binding motif RL PF17797.1 VBB33188.1 - 0.011 15.6 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 RL domain PseudoU_synth_1 PF01416.20 VBB33188.1 - 0.027 14.9 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridine synthase HMG_box PF00505.19 VBB33189.1 - 7.5e-14 51.9 1.7 1.4e-13 51.0 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB33189.1 - 2.1e-10 41.1 1.8 4.1e-10 40.1 1.8 1.4 1 0 0 1 1 1 1 HMG-box domain FOXP-CC PF16159.5 VBB33189.1 - 0.0019 18.8 1.2 0.32 11.7 0.1 2.7 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 VBB33189.1 - 0.0074 16.5 0.9 0.012 15.8 0.9 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 VBB33189.1 - 0.0083 16.9 2.5 1.5 9.9 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB33189.1 - 0.0091 16.4 3.4 0.32 11.5 0.2 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type CHDNT PF08073.12 VBB33189.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain Zap1_zf2 PF18217.1 VBB33189.1 - 0.11 12.6 0.6 0.11 12.6 0.6 2.3 2 0 0 2 2 2 0 Zap1 zinc finger 2 BAH PF01426.18 VBB33191.1 - 1.4e-13 50.7 0.4 2.5e-13 50.0 0.1 1.6 2 0 0 2 2 2 1 BAH domain KCNQ2_u3 PF16642.5 VBB33191.1 - 5.7 8.0 8.0 9.9 7.2 0.1 3.1 2 1 1 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DUF501 PF04417.12 VBB33192.1 - 0.00024 20.9 0.7 0.0004 20.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF501) PH PF00169.29 VBB33193.1 - 9.3e-10 39.0 1.3 2.3e-09 37.7 1.3 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 VBB33193.1 - 0.048 14.1 2.0 0.15 12.5 2.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain FlaG PF03646.15 VBB33193.1 - 0.6 10.3 6.7 0.076 13.2 1.1 2.3 2 0 0 2 2 2 0 FlaG protein Caskin-Pro-rich PF16907.5 VBB33193.1 - 1.2 9.7 7.3 0.64 10.6 3.2 2.5 2 0 0 2 2 2 0 Proline rich region of Caskin proteins FAT PF02259.23 VBB33194.1 - 6e-72 242.7 5.4 1.6e-54 185.4 9.9 2.4 2 0 0 2 2 2 2 FAT domain PI3_PI4_kinase PF00454.27 VBB33194.1 - 4.2e-71 239.7 0.2 7.2e-71 238.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 VBB33194.1 - 3.5e-34 117.2 12.6 6.1e-33 113.2 3.8 5.4 5 1 0 5 5 5 1 FKBP12-rapamycin binding domain FATC PF02260.20 VBB33194.1 - 9.1e-14 51.0 0.4 9.1e-14 51.0 0.4 2.2 2 0 0 2 2 2 1 FATC domain TPR_17 PF13431.6 VBB33194.1 - 0.017 15.5 0.9 0.017 15.5 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 VBB33194.1 - 0.17 11.9 1.0 0.5 10.4 0.5 2.0 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_19 PF14559.6 VBB33194.1 - 0.28 11.7 5.0 11 6.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33194.1 - 0.33 11.2 7.8 1.7 8.9 0.2 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 VBB33195.1 - 0.007 15.8 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Nodulin PF02451.15 VBB33195.1 - 0.077 12.5 0.1 0.091 12.2 0.1 1.1 1 0 0 1 1 1 0 Nodulin HEAT PF02985.22 VBB33197.1 - 1.5e-46 152.4 23.0 0.0005 20.1 0.0 13.5 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 VBB33197.1 - 7.6e-36 122.4 12.6 3.7e-07 30.4 0.1 8.5 2 1 6 9 9 9 8 HEAT repeats Vac14_Fab1_bd PF12755.7 VBB33197.1 - 7.3e-16 58.5 3.1 7.2e-05 23.3 0.0 7.7 3 1 3 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 VBB33197.1 - 2.4e-11 44.0 11.5 0.00043 20.4 0.1 5.9 2 1 3 6 6 6 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 VBB33197.1 - 2.3e-10 39.7 1.3 7.7e-05 21.4 0.1 3.1 1 1 1 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.8 VBB33197.1 - 5.2e-09 36.0 2.0 0.0022 17.6 0.1 4.7 1 1 3 5 5 5 2 CLASP N terminal Ecm29 PF13001.7 VBB33197.1 - 1.1e-05 24.3 1.3 0.88 8.2 0.1 3.8 4 0 0 4 4 4 3 Proteasome stabiliser HEAT_EZ PF13513.6 VBB33197.1 - 1.1e-05 25.8 13.5 9.1 6.9 0.1 9.6 9 4 1 11 11 11 1 HEAT-like repeat TAF6_C PF07571.13 VBB33197.1 - 0.00025 21.3 0.1 8.4 6.8 0.0 4.8 4 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain Nipped-B_C PF12830.7 VBB33197.1 - 0.001 19.1 0.3 0.99 9.3 0.0 3.4 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus HEAT_PBS PF03130.16 VBB33197.1 - 0.037 14.7 1.5 65 4.6 0.0 5.0 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 VBB33197.1 - 0.089 12.7 1.0 15 5.5 0.0 3.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central IFRD PF05004.13 VBB33197.1 - 0.11 11.5 8.8 0.34 10.0 0.1 4.2 2 1 2 5 5 5 0 Interferon-related developmental regulator (IFRD) MIP PF00230.20 VBB33198.1 - 2.9e-36 125.3 11.3 3.6e-36 125.0 11.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein An_peroxidase PF03098.15 VBB33199.1 - 5.6e-61 206.7 0.0 6.2e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF974 PF06159.13 VBB33200.1 - 1.6e-73 247.5 0.1 1.9e-73 247.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) NAC PF01849.18 VBB33201.1 - 8.1e-24 83.4 0.3 2.1e-23 82.0 0.3 1.8 1 0 0 1 1 1 1 NAC domain DUF3440 PF11922.8 VBB33201.1 - 0.0085 15.8 0.3 0.015 15.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3440) TFIIE-A_C PF11521.8 VBB33201.1 - 0.083 13.2 0.5 0.083 13.2 0.5 2.2 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Peptidase_M1 PF01433.20 VBB33202.1 - 1.9e-60 204.1 1.5 3e-60 203.5 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 VBB33202.1 - 5.6e-32 111.4 0.0 1.3e-31 110.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 VBB33202.1 - 8.2e-17 61.7 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Glyco_hydro_31 PF01055.26 VBB33203.1 - 1.1e-127 426.9 5.2 1.5e-127 426.5 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 VBB33203.1 - 6.2e-16 58.6 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 VBB33203.1 - 2.7e-08 34.0 0.4 2.7e-08 34.0 0.4 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Trefoil PF00088.18 VBB33203.1 - 3.6e-08 33.1 1.4 3.6e-08 33.1 1.4 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Transposase_1 PF01359.18 VBB33203.1 - 0.13 12.1 0.4 0.3 10.9 0.4 1.6 1 0 0 1 1 1 0 Transposase (partial DDE domain) NUDIX_2 PF13869.6 VBB33204.1 - 4.8e-36 124.1 0.2 5.1e-36 124.0 0.2 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RrnaAD PF00398.20 VBB33205.1 - 1.9e-33 115.7 0.0 2.2e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 VBB33205.1 - 0.0051 16.4 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 VBB33205.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 VBB33205.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Guanylate_kin PF00625.21 VBB33206.1 - 1.9e-53 180.9 0.3 1.7e-43 148.4 0.0 2.0 2 0 0 2 2 2 2 Guanylate kinase AAA_16 PF13191.6 VBB33206.1 - 0.00099 19.5 0.1 0.1 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 VBB33206.1 - 0.0017 18.6 0.1 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 VBB33206.1 - 0.0078 16.3 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 VBB33206.1 - 0.019 15.1 0.1 0.11 12.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 VBB33206.1 - 0.051 14.1 0.1 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 VBB33206.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 VBB33206.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 VBB33206.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NTPase Leader_Erm PF08253.11 VBB33206.1 - 0.1 12.9 1.3 0.13 12.5 0.1 1.8 2 0 0 2 2 1 0 Erm Leader peptide Zeta_toxin PF06414.12 VBB33206.1 - 0.13 11.5 0.3 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 VBB33206.1 - 0.15 12.6 0.1 0.65 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 VBB33206.1 - 0.39 11.2 4.6 2.8 8.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 VBB33207.1 - 2e-17 63.5 0.5 2.5e-17 63.3 0.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Metallophos PF00149.28 VBB33209.1 - 2.6e-34 119.5 0.0 4.1e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 VBB33209.1 - 0.0042 17.3 0.1 0.0091 16.3 0.1 1.6 1 1 0 1 1 1 1 PPP5 TPR repeat region DUF5378 PF17349.2 VBB33209.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5378) P21-Arc PF04062.14 VBB33209.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.1 3 0 0 3 3 3 0 ARP2/3 complex ARPC3 (21 kDa) subunit EB PF01683.18 VBB33210.1 - 3.8e-15 55.9 34.9 3.6e-08 33.6 6.4 6.9 3 3 4 7 7 7 4 EB module DJ-1_PfpI PF01965.24 VBB33211.1 - 4.2e-51 173.0 0.2 4.8e-51 172.8 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 VBB33211.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 VBB33211.1 - 0.2 11.3 0.1 21 4.7 0.1 2.4 1 1 1 2 2 2 0 ThiJ/PfpI family-like Mito_carr PF00153.27 VBB33212.1 - 3.4e-58 193.6 1.3 7.7e-20 70.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GST_C_3 PF14497.6 VBB33213.1 - 3.8e-10 39.8 0.0 2.2e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 VBB33213.1 - 2.4e-07 30.9 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 VBB33213.1 - 5.5e-06 26.7 0.0 8.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 VBB33213.1 - 0.00073 19.5 0.0 0.0022 18.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 VBB33213.1 - 0.002 18.5 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HECA PF15353.6 VBB33214.1 - 0.028 14.6 2.2 0.093 13.0 2.2 1.9 1 0 0 1 1 1 0 Headcase protein family homologue Acyltransferase PF01553.21 VBB33215.1 - 5.1e-20 71.5 0.1 7.7e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 VBB33215.1 - 4.8e-10 39.4 0.3 1e-09 38.3 0.1 1.7 2 0 0 2 2 2 1 Acyltransferase C-terminus Rft-1 PF04506.13 VBB33217.1 - 2.1e-73 247.8 22.1 3e-73 247.3 22.1 1.1 1 0 0 1 1 1 1 Rft protein APG12 PF04110.13 VBB33217.1 - 4.8e-29 100.6 0.1 1e-28 99.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 VBB33217.1 - 3.5e-05 23.9 0.0 0.00017 21.7 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like 7tm_1 PF00001.21 VBB33219.1 - 3.6e-05 23.2 8.9 4.7e-05 22.9 8.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NOA36 PF06524.12 VBB33219.1 - 0.0018 17.6 5.9 0.0023 17.3 5.9 1.3 1 0 0 1 1 1 1 NOA36 protein Cwf_Cwc_15 PF04889.12 VBB33219.1 - 0.005 16.6 6.1 0.0058 16.4 6.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 VBB33219.1 - 0.029 14.4 2.8 0.042 13.9 2.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4781 PF16013.5 VBB33219.1 - 0.054 12.3 1.1 0.29 9.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) 7TM_GPCR_Srsx PF10320.9 VBB33219.1 - 0.058 12.8 3.6 0.073 12.4 3.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Sigma70_ner PF04546.13 VBB33219.1 - 0.067 13.1 1.2 0.077 12.9 1.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 VBB33219.1 - 0.28 10.8 1.6 0.47 10.1 1.6 1.4 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 VBB33219.1 - 0.68 9.0 16.4 0.86 8.7 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 VBB33219.1 - 0.87 10.0 19.4 1.9 8.9 19.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 VBB33219.1 - 0.91 9.9 12.5 1.6 9.2 12.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2076 PF09849.9 VBB33219.1 - 1.8 8.5 6.7 2.4 8.1 6.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_phi PF04931.13 VBB33219.1 - 4.9 5.1 16.5 7.2 4.6 16.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpb1_2 PF00623.20 VBB33220.1 - 1.9e-58 197.4 0.3 4.7e-58 196.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 VBB33220.1 - 2.1e-29 102.5 0.0 3.9e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 VBB33220.1 - 2.3e-22 79.8 9.8 4.1e-22 78.9 3.7 3.5 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 Phtf-FEM1B_bdg PF12129.8 VBB33221.1 - 0.44 10.4 2.4 0.2 11.5 0.5 1.4 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor TM2 PF05154.16 VBB33222.1 - 0.0063 16.8 1.9 0.0063 16.8 1.9 2.8 3 0 0 3 3 3 1 TM2 domain zf-C4 PF00105.18 VBB33223.1 - 2e-30 105.1 17.3 2e-30 105.1 17.3 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB33223.1 - 1.2e-25 90.4 2.8 6.5e-25 87.9 2.8 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor GTP_EFTU PF00009.27 VBB33224.1 - 1.9e-60 203.7 0.2 4e-60 202.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 VBB33224.1 - 1.1e-36 125.2 0.0 3e-36 123.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 VBB33224.1 - 3.3e-27 94.4 0.0 7.4e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 VBB33224.1 - 1.4e-11 44.6 0.0 4.5e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 VBB33224.1 - 2.9e-05 23.9 0.0 9.9e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_C PF00679.24 VBB33224.1 - 0.0013 18.7 0.0 0.004 17.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 VBB33224.1 - 0.0022 18.1 0.0 0.0066 16.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 VBB33224.1 - 0.0054 17.2 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain AIG1 PF04548.16 VBB33224.1 - 0.0093 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF442 PF04273.13 VBB33224.1 - 0.061 13.4 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) SnoaL_2 PF12680.7 VBB33224.1 - 0.1 13.2 0.0 0.46 11.2 0.0 2.1 1 0 0 1 1 1 0 SnoaL-like domain SAC3_GANP PF03399.16 VBB33225.1 - 4.9e-99 331.4 11.0 6.7e-99 331.0 11.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 VBB33225.1 - 5.5e-06 26.4 0.8 2.8e-05 24.1 0.1 2.1 1 1 1 2 2 2 1 CSN8/PSMD8/EIF3K family EMP24_GP25L PF01105.24 VBB33226.1 - 3e-15 56.6 4.1 3.7e-15 56.3 4.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arm-DNA-bind_5 PF17293.2 VBB33226.1 - 0.0085 16.5 0.6 0.014 15.8 0.6 1.3 1 0 0 1 1 1 1 Arm DNA-binding domain CorA PF01544.18 VBB33226.1 - 0.015 14.6 0.9 0.018 14.4 0.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TraC_F_IV PF11130.8 VBB33226.1 - 0.11 12.0 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Coat_X PF07552.11 VBB33226.1 - 0.49 10.2 6.5 1.1 9.2 6.5 1.5 1 0 0 1 1 1 0 Spore Coat Protein X and V domain HMG_box PF00505.19 VBB33227.1 - 3.7e-16 59.3 6.4 7.5e-16 58.3 6.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB33227.1 - 6.6e-09 36.2 4.8 2e-08 34.7 4.8 1.9 1 0 0 1 1 1 1 HMG-box domain Peptidase_M48_N PF16491.5 VBB33230.1 - 5.9e-61 205.5 8.0 5.9e-61 205.5 8.0 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 VBB33230.1 - 1.2e-46 158.9 0.0 2.4e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 La PF05383.17 VBB33231.1 - 6.6e-20 70.9 0.0 1.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 VBB33231.1 - 3.9e-18 65.4 2.5 3.9e-18 65.4 2.5 3.3 3 1 0 3 3 3 2 RNA binding motif RRM_1 PF00076.22 VBB33231.1 - 1.4e-13 50.5 2.7 2.2e-09 37.0 0.9 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRO8NT PF08082.11 VBB33231.1 - 0.0031 17.5 0.7 0.01 15.8 0.4 2.0 1 1 1 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain BRAP2 PF07576.12 VBB33231.1 - 0.017 15.4 0.3 0.04 14.1 0.3 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 PHM7_cyt PF14703.6 VBB33231.1 - 0.05 13.8 9.6 0.59 10.3 1.4 3.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF1738 PF08401.11 VBB33231.1 - 8.3 6.5 9.6 0.66 10.1 2.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1738) LSM PF01423.22 VBB33233.1 - 9.5e-18 63.7 0.4 3.7e-17 61.8 0.0 2.1 3 0 0 3 3 3 1 LSM domain TTR-52 PF01060.23 VBB33233.1 - 7.1e-16 58.7 0.0 1.5e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Transthyretin-like family RhlB PF12300.8 VBB33233.1 - 0.85 9.7 6.9 1.3 9.1 6.9 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Arteri_GP4 PF02497.15 VBB33234.1 - 0.1 12.7 0.5 0.16 12.1 0.4 1.4 1 1 0 1 1 1 0 Arterivirus glycoprotein TPR_12 PF13424.6 VBB33235.1 - 1.2e-71 236.9 25.5 6e-20 71.3 0.9 4.6 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 VBB33235.1 - 1.2e-59 196.7 15.0 3.1e-14 52.3 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 VBB33235.1 - 6.5e-33 110.4 14.2 2.4e-06 27.2 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33235.1 - 3.8e-28 96.1 29.1 1.4e-07 31.0 0.2 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33235.1 - 1.3e-21 74.9 27.5 0.00011 22.0 1.7 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33235.1 - 1.8e-15 55.8 25.9 0.011 15.9 1.4 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 VBB33235.1 - 1.9e-14 53.8 0.3 1.9e-14 53.8 0.3 2.6 3 0 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 VBB33235.1 - 2.4e-13 50.5 11.2 0.0021 18.7 0.1 5.6 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33235.1 - 2e-10 40.6 11.5 0.32 11.9 0.0 6.6 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 VBB33235.1 - 2.3e-10 40.1 6.8 0.25 11.8 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33235.1 - 1.3e-09 38.5 18.2 0.0015 19.0 0.1 4.7 3 1 1 5 5 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 VBB33235.1 - 3e-06 27.3 0.0 11 6.9 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33235.1 - 3.6e-06 27.1 10.8 0.0079 16.4 0.2 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 VBB33235.1 - 0.0003 20.8 1.2 0.96 9.8 0.0 5.0 6 0 0 6 6 5 1 PPR repeat JIP_LZII PF16471.5 VBB33235.1 - 0.0021 18.2 2.5 0.0021 18.2 2.5 3.0 3 0 0 3 3 2 1 JNK-interacting protein leucine zipper II NUDE_C PF04880.13 VBB33235.1 - 0.0034 17.9 0.7 0.0079 16.7 0.7 1.6 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Wzy_C_2 PF11846.8 VBB33235.1 - 0.019 14.9 1.0 7.3 6.5 0.0 3.6 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal SHNi-TPR PF10516.9 VBB33235.1 - 0.035 13.6 3.1 2 8.0 0.1 4.1 4 0 0 4 4 4 0 SHNi-TPR TPR_11 PF13414.6 VBB33235.1 - 0.04 13.6 0.5 0.04 13.6 0.5 6.1 6 0 0 6 6 6 0 TPR repeat PPR_2 PF13041.6 VBB33235.1 - 0.083 13.1 0.5 22 5.3 0.0 3.3 3 0 0 3 3 2 0 PPR repeat family Csm1_N PF18504.1 VBB33235.1 - 0.1 12.9 8.5 0.099 13.0 5.5 2.7 1 1 0 2 2 1 0 Csm1 N-terminal domain TPR_3 PF07720.12 VBB33235.1 - 0.25 11.4 15.2 0.88 9.6 0.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 VBB33235.1 - 0.32 11.0 9.6 5 7.2 0.1 4.8 4 1 1 5 5 4 0 Protein of unknown function (DUF627) Mod_r PF07200.13 VBB33235.1 - 0.59 10.2 16.7 2.6 8.2 9.7 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.11 VBB33235.1 - 0.66 10.1 7.5 0.39 10.8 3.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 VBB33235.1 - 1 7.2 5.9 1.5 6.6 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 VBB33235.1 - 3.4 7.9 19.7 0.095 12.9 10.0 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 VBB33235.1 - 4.5 7.7 9.7 2.1 8.8 4.3 3.1 2 1 2 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 VBB33235.1 - 9.2 6.3 9.2 20 5.2 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_17 PF13431.6 VBB33236.1 - 9.1e-09 35.1 0.6 3.5e-05 23.9 0.8 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33236.1 - 5.4e-08 33.2 1.7 8.7e-08 32.6 1.3 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33236.1 - 1.2e-07 31.3 3.3 0.049 13.7 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33236.1 - 1.7e-06 27.6 1.1 0.055 13.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33236.1 - 1.6e-05 24.7 0.1 0.0073 16.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB33236.1 - 0.00011 22.2 0.8 0.12 12.5 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB33236.1 - 0.00012 21.7 0.1 0.013 15.1 0.1 2.4 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 VBB33236.1 - 0.001 19.2 0.9 0.01 16.0 0.6 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB33236.1 - 0.0013 19.2 1.2 9.4 7.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 VBB33236.1 - 0.0034 18.0 0.6 1.2 9.9 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB33236.1 - 0.0063 16.8 1.1 0.033 14.5 0.9 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 VBB33236.1 - 0.0078 15.5 0.1 0.068 12.4 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33236.1 - 0.008 16.9 0.4 0.48 11.4 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 VBB33236.1 - 0.033 14.5 0.3 0.048 14.0 0.3 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 VBB33237.1 - 2.1e-10 40.3 0.0 3.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB33237.1 - 5.8e-06 25.9 0.0 9.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 VBB33237.1 - 0.032 14.7 0.9 14 6.4 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB33237.1 - 1.1 10.3 4.0 8.3 7.6 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger TPR_17 PF13431.6 VBB33238.1 - 8.8e-09 35.2 0.6 3.4e-05 23.9 0.8 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33238.1 - 3.3e-07 30.7 1.6 5.2e-07 30.1 1.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33238.1 - 4e-07 29.7 2.9 0.049 13.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33238.1 - 6.7e-06 25.7 0.9 0.054 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33238.1 - 7.9e-05 22.6 0.1 0.0072 16.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB33238.1 - 0.00019 21.5 0.6 0.076 13.2 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB33238.1 - 0.00049 19.7 0.1 0.058 13.1 0.0 2.4 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 VBB33238.1 - 0.0058 16.8 1.0 0.067 13.4 0.6 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB33238.1 - 0.0059 17.2 1.0 9.3 7.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB33238.1 - 0.0089 16.3 1.2 0.033 14.5 1.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB33238.1 - 0.012 16.2 0.7 4.2 8.1 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 VBB33238.1 - 0.02 14.1 0.0 0.062 12.5 0.0 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 VBB33238.1 - 0.042 14.2 0.4 0.063 13.6 0.4 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33238.1 - 0.045 14.6 0.3 3 8.9 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat Cu2_monoox_C PF03712.15 VBB33239.1 - 6.4e-31 107.0 0.0 1.1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain NHL PF01436.21 VBB33239.1 - 1.7e-24 84.5 1.8 1.5e-06 28.0 0.0 4.9 4 0 0 4 4 4 4 NHL repeat Cu2_monooxygen PF01082.20 VBB33239.1 - 3.4e-16 59.7 0.0 7.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Lactonase PF10282.9 VBB33239.1 - 2.7e-05 23.6 0.6 0.25 10.6 0.1 2.6 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 VBB33239.1 - 0.00019 21.1 0.1 0.5 9.9 0.1 3.3 2 2 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 VBB33239.1 - 0.00069 19.6 0.1 0.15 12.0 0.0 2.9 2 1 0 2 2 2 1 Esterase-like activity of phytase Sigma_reg_N PF13800.6 VBB33239.1 - 0.11 12.7 1.3 5 7.5 0.9 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal His_Phos_2 PF00328.22 VBB33240.1 - 8e-21 74.8 0.0 4.4e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CGI-121 PF08617.10 VBB33241.1 - 8.6e-38 130.0 0.1 9.8e-38 129.8 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 pP_pnuc_1 PF18165.1 VBB33241.1 - 0.037 13.9 0.3 0.97 9.3 0.1 2.2 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease DUF2774 PF11242.8 VBB33241.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Ldh_1_C PF02866.18 VBB33242.1 - 9.9e-50 168.7 0.1 2.2e-49 167.6 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 VBB33242.1 - 5.5e-46 156.2 0.0 1.1e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MRP-S31 PF15433.6 VBB33242.1 - 2.7e-14 53.6 15.2 4.7e-14 52.8 15.2 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 3Beta_HSD PF01073.19 VBB33242.1 - 0.0042 16.1 0.0 0.009 15.0 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Alanine_zipper PF11839.8 VBB33242.1 - 0.05 14.0 5.9 0.97 9.9 0.5 2.6 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Semialdhyde_dh PF01118.24 VBB33242.1 - 0.13 12.7 0.2 1 9.8 0.0 2.7 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 VBB33243.1 - 1.6e-39 135.3 0.1 4.4e-39 133.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB33243.1 - 1e-06 28.5 0.1 2.5e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 VBB33243.1 - 1.4e-06 28.7 0.1 0.0061 16.8 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 VBB33243.1 - 4.3e-06 27.0 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 VBB33243.1 - 8.1e-06 26.3 0.1 0.0046 17.4 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 VBB33243.1 - 1.1e-05 25.5 0.2 9.6e-05 22.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 VBB33243.1 - 9.9e-05 22.1 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 VBB33243.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 VBB33243.1 - 0.0043 16.3 0.0 0.0082 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 VBB33243.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 VBB33243.1 - 0.012 15.3 0.1 0.053 13.2 0.1 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 VBB33243.1 - 0.012 14.9 0.1 0.19 11.1 0.1 2.3 1 1 1 2 2 2 0 KaiC TIP49 PF06068.13 VBB33243.1 - 0.013 14.7 0.4 0.042 13.1 0.1 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 VBB33243.1 - 0.022 14.3 0.1 0.11 12.0 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 VBB33243.1 - 0.024 14.1 0.1 0.12 11.8 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 VBB33243.1 - 0.027 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRAF_BIRC3_bd PF16673.5 VBB33243.1 - 0.038 13.8 0.2 0.86 9.4 0.0 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain AAA_33 PF13671.6 VBB33243.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 VBB33243.1 - 0.053 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 VBB33243.1 - 0.079 12.0 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_18 PF13238.6 VBB33243.1 - 0.088 13.4 0.1 0.36 11.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 VBB33243.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 VBB33243.1 - 0.11 12.4 0.4 0.59 10.0 0.1 2.3 2 1 1 3 3 3 0 NACHT domain TsaE PF02367.17 VBB33243.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 VBB33243.1 - 0.14 12.1 2.3 3.6 7.5 0.3 3.1 3 1 0 3 3 3 0 NTPase AAA_24 PF13479.6 VBB33243.1 - 0.16 11.7 0.1 0.42 10.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 VBB33243.1 - 0.16 11.5 0.1 0.36 10.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 VBB33243.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 VBB33243.1 - 0.18 10.9 0.3 3.2 6.9 0.1 2.4 3 0 0 3 3 3 0 NB-ARC domain fn3 PF00041.21 VBB33246.1 - 5.4e-56 186.9 7.9 1.2e-16 60.8 1.5 5.2 4 1 0 4 4 4 4 Fibronectin type III domain Ig_3 PF13927.6 VBB33246.1 - 2.8e-13 50.3 0.3 2.4e-06 28.1 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 VBB33246.1 - 6e-13 48.7 0.0 5.7e-05 23.1 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 VBB33246.1 - 1.8e-11 44.4 0.7 0.016 15.8 0.4 4.8 4 1 0 4 4 4 4 Purple acid Phosphatase, N-terminal domain ig PF00047.25 VBB33246.1 - 2.4e-10 40.4 0.0 4.8e-05 23.5 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 VBB33246.1 - 1.1e-05 25.7 0.2 0.1 13.0 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain fn3_2 PF16893.5 VBB33246.1 - 0.00036 20.6 1.0 0.19 11.9 0.1 3.7 4 0 0 4 4 4 1 Fibronectin type III domain Interfer-bind PF09294.10 VBB33246.1 - 0.0044 17.3 3.4 16 5.9 0.8 4.6 4 2 2 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III FAM53 PF15242.6 VBB33246.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Family of FAM53 Kinesin PF00225.23 VBB33247.1 - 8.8e-98 327.3 0.4 1.7e-97 326.3 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain BBS1 PF14779.6 VBB33247.1 - 1.7e-92 309.4 0.1 5.4e-91 304.5 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 Microtub_bd PF16796.5 VBB33247.1 - 1.2e-45 155.1 4.5 6.2e-45 152.8 0.1 3.0 2 1 0 2 2 2 1 Microtubule binding FHA PF00498.26 VBB33248.1 - 2.3e-13 50.3 0.1 3.1e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 VBB33248.1 - 0.0019 18.5 0.0 0.0032 17.7 0.0 1.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain WD40_like PF17005.5 VBB33250.1 - 0.00012 21.5 0.1 0.03 13.7 0.1 2.4 2 0 0 2 2 2 2 WD40-like domain WD40 PF00400.32 VBB33250.1 - 0.00091 20.0 6.7 0.034 15.0 0.2 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB33250.1 - 0.067 13.5 0.0 17 5.8 0.0 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Erf4 PF10256.9 VBB33251.1 - 0.0026 17.9 0.3 0.55 10.4 0.0 3.6 3 0 0 3 3 3 1 Golgin subfamily A member 7/ERF4 family RhaA PF06134.11 VBB33251.1 - 0.012 14.8 0.3 0.28 10.3 0.2 2.1 2 0 0 2 2 2 0 L-rhamnose isomerase (RhaA) Sec7_N PF12783.7 VBB33251.1 - 0.045 13.7 2.9 0.094 12.6 1.4 2.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 VBB33251.1 - 0.05 13.9 0.1 22 5.7 0.0 3.6 2 0 0 2 2 2 0 HEAT repeat Myosin_head PF00063.21 VBB33252.1 - 9.8e-64 215.8 0.0 9.8e-64 215.8 0.0 2.9 3 0 0 3 3 3 1 Myosin head (motor domain) DUF4472 PF14739.6 VBB33252.1 - 0.0051 17.5 8.3 0.0051 17.5 8.3 7.8 2 2 3 7 7 7 2 Domain of unknown function (DUF4472) IQ PF00612.27 VBB33252.1 - 0.27 11.2 1.0 17 5.6 0.0 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF948 PF06103.11 VBB33252.1 - 4.8 7.5 31.3 1.9 8.8 0.5 5.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Recep_L_domain PF01030.24 VBB33253.1 - 1.7e-27 95.7 0.3 2e-27 95.5 0.3 1.1 1 0 0 1 1 1 1 Receptor L domain Metallophos PF00149.28 VBB33254.1 - 4.6e-14 53.4 0.1 5.5e-09 36.8 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB33254.1 - 1.6e-06 28.4 0.1 2.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 VBB33256.1 - 1.6e-61 208.0 0.0 3e-61 207.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33256.1 - 1.1e-27 96.9 0.0 1.8e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB33256.1 - 3.9e-08 33.0 0.0 6.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB33256.1 - 0.00012 21.0 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB33256.1 - 0.0091 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB33256.1 - 0.031 14.2 0.1 0.091 12.7 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family G-patch PF01585.23 VBB33257.1 - 2.7e-11 43.2 0.4 5.3e-11 42.2 0.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 VBB33257.1 - 0.00074 19.6 0.3 0.00074 19.6 0.3 2.1 2 0 0 2 2 2 1 G-patch domain COesterase PF00135.28 VBB33258.1 - 7.2e-16 58.1 0.0 8.4e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF148 PF02520.17 VBB33260.1 - 0.00093 19.3 1.1 0.0016 18.6 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 RRM_1 PF00076.22 VBB33261.1 - 1.5e-19 69.6 0.0 2.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB33261.1 - 2.4e-06 27.6 0.0 4.8e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 VBB33261.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 VBB33262.1 - 3.2e-10 39.7 0.0 4.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB33262.1 - 3.3e-05 23.5 0.0 4.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KorB_C PF06613.11 VBB33262.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Ank_4 PF13637.6 VBB33263.1 - 7.8e-18 64.6 4.0 2.7e-07 31.0 0.4 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB33263.1 - 6.1e-16 58.8 0.3 9.4e-08 32.5 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB33263.1 - 1.1e-12 47.9 0.9 5.1e-05 23.5 0.1 3.3 2 1 0 3 3 3 2 Ankyrin repeats (many copies) FERM_M PF00373.18 VBB33263.1 - 1.6e-12 47.9 0.1 4.1e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 FERM central domain Ank PF00023.30 VBB33263.1 - 2.2e-12 46.8 3.4 0.0018 18.6 0.0 4.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 VBB33263.1 - 7.6e-12 44.3 0.4 0.011 16.2 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat NUDIX_5 PF16705.5 VBB33263.1 - 0.00059 19.6 0.0 0.014 15.2 0.0 2.3 1 1 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT DUF4427 PF14468.6 VBB33263.1 - 0.1 12.7 0.0 7.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) AA_permease PF00324.21 VBB33264.1 - 7.8e-72 242.4 14.1 9.3e-72 242.1 14.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 VBB33264.1 - 1.4e-66 225.4 0.2 3.6e-49 167.9 0.1 2.1 2 0 0 2 2 2 2 Solute carrier family 12 Patched PF02460.18 VBB33265.1 - 6.9e-12 44.3 0.0 1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Patched family HRM PF02793.22 VBB33266.1 - 2.1e-06 27.9 1.1 3.6e-06 27.2 1.1 1.4 1 0 0 1 1 1 1 Hormone receptor domain Macoilin PF09726.9 VBB33267.1 - 0.093 11.3 25.3 0.11 11.0 25.3 1.2 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 VBB33267.1 - 0.16 11.3 11.1 0.2 11.0 11.1 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 VBB33267.1 - 0.55 9.7 11.7 0.76 9.3 11.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TLV_coat PF00429.19 VBB33267.1 - 2.2 6.8 10.3 3 6.4 10.3 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) SPX PF03105.19 VBB33267.1 - 2.8 7.7 20.6 3.7 7.4 20.6 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 VBB33267.1 - 4.3 6.1 17.3 5.1 5.8 17.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PNISR PF15996.5 VBB33267.1 - 6.5 7.0 8.2 9.4 6.5 8.2 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Herpes_pp85 PF04637.12 VBB33267.1 - 8 4.7 15.0 12 4.1 15.0 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CBM_14 PF01607.24 VBB33268.1 - 7.3e-08 32.5 17.7 2.2e-05 24.5 3.5 2.9 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain CSN7a_helixI PF18392.1 VBB33268.1 - 0.047 13.6 1.2 0.09 12.7 1.2 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain PNP_phzG_C PF10590.9 VBB33269.1 - 3.2e-18 65.5 1.3 5.6e-18 64.8 1.3 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 VBB33269.1 - 1.5e-16 60.3 0.0 2.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 VBB33269.1 - 3.5e-06 27.5 0.0 8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 VBB33269.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Pkinase PF00069.25 VBB33270.1 - 4.2e-07 29.6 0.1 5.6e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33270.1 - 0.00076 18.8 0.1 0.0009 18.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RabGAP-TBC PF00566.18 VBB33271.1 - 2.2e-25 89.6 4.1 1.1e-22 80.8 0.5 2.7 1 1 1 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 VBB33271.1 - 1.9e-05 24.2 0.2 0.003 17.1 0.2 2.5 2 1 0 2 2 2 2 Rab-binding domain (RBD) Dynein_light PF01221.18 VBB33272.1 - 1.5e-18 66.9 0.1 2.1e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 SRP1_TIP1 PF00660.17 VBB33272.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Seripauperin and TIP1 family 7tm_1 PF00001.21 VBB33273.1 - 7.4e-08 32.0 8.4 1.3e-07 31.2 6.5 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Treslin_N PF15292.6 VBB33274.1 - 3.5e-07 29.0 0.7 5.5e-07 28.3 0.7 1.2 1 0 0 1 1 1 1 Treslin N-terminus MFS_1 PF07690.16 VBB33275.1 - 2.2e-54 184.7 50.7 2.6e-52 177.9 40.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB33275.1 - 0.0016 17.4 36.9 0.0093 14.9 36.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Ni_hydr_CYTB PF01292.20 VBB33275.1 - 3.9 7.0 16.6 0.076 12.6 3.2 3.3 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 IL17 PF06083.11 VBB33276.1 - 3.8e-08 33.7 0.3 6.5e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Interleukin-17 DUF229 PF02995.17 VBB33277.1 - 1.8e-14 53.3 0.4 2.3e-14 52.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Branch PF02485.21 VBB33278.1 - 5.7e-36 124.3 0.1 1e-35 123.5 0.1 1.4 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Ins_beta PF03488.14 VBB33279.1 - 0.018 15.0 0.4 0.032 14.2 0.4 1.5 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Insulin PF00049.18 VBB33279.1 - 0.15 13.1 0.6 0.27 12.3 0.2 1.6 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family Arm_2 PF04826.13 VBB33280.1 - 1.2e-08 34.8 4.0 3.3e-08 33.3 4.0 1.7 1 1 0 1 1 1 1 Armadillo-like HlyIII PF03006.20 VBB33281.1 - 5e-41 140.9 19.2 5.9e-41 140.6 19.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_4 PF12730.7 VBB33281.1 - 0.091 12.7 5.8 0.71 9.8 5.8 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein PsbN PF02468.15 VBB33281.1 - 7.1 6.6 5.5 18 5.3 0.9 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) CUB PF00431.20 VBB33282.1 - 2.8e-05 24.4 0.0 4.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 CUB domain Tweety PF04906.13 VBB33283.1 - 5.4e-34 117.6 11.6 6.6e-34 117.3 11.6 1.1 1 0 0 1 1 1 1 Tweety IncD PF17628.2 VBB33283.1 - 0.0039 17.0 0.1 0.0039 17.0 0.1 2.5 3 0 0 3 3 3 1 Inclusion membrane protein D DUF1345 PF07077.11 VBB33283.1 - 0.012 15.3 3.6 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) NPV_P10 PF05531.12 VBB33283.1 - 0.016 15.6 3.1 4.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4131 PF13567.6 VBB33283.1 - 0.019 14.6 1.8 0.019 14.6 1.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3810 PF12725.7 VBB33283.1 - 0.76 9.1 5.6 1.5 8.1 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2207 PF09972.9 VBB33283.1 - 1.6 7.4 12.2 0.33 9.7 1.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 VBB33283.1 - 3.1 7.5 14.3 0.82 9.4 1.7 2.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF373 PF04123.13 VBB33283.1 - 4 6.8 7.3 6.8 6.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) TMEM52 PF14979.6 VBB33283.1 - 7.5 6.5 8.5 14 5.6 4.2 2.7 2 0 0 2 2 2 0 Transmembrane 52 FYVE_2 PF02318.16 VBB33284.1 - 1.2e-05 25.5 8.7 1.6e-05 25.1 8.7 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger Taxilin PF09728.9 VBB33284.1 - 0.00047 19.4 7.7 0.00053 19.3 7.7 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1367 PF07105.11 VBB33284.1 - 0.0054 16.4 0.2 0.0064 16.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1367) ComX PF05952.12 VBB33284.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Ser_hydrolase PF06821.13 VBB33284.1 - 0.06 13.2 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase LMBR1 PF04791.16 VBB33284.1 - 0.19 10.6 0.5 0.2 10.5 0.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Tubulin PF00091.25 VBB33285.1 - 6.5e-68 228.8 0.1 8.4e-68 228.5 0.1 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB33285.1 - 1.5e-41 141.5 0.0 2.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 VBB33285.1 - 0.00048 19.9 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Cadherin PF00028.17 VBB33286.1 - 6.8e-20 71.3 0.1 1.2e-14 54.5 0.1 3.6 3 0 0 3 3 3 2 Cadherin domain Cadherin_3 PF16184.5 VBB33286.1 - 0.00069 19.6 0.0 12 6.0 0.0 3.7 3 0 0 3 3 3 3 Cadherin-like Cadherin_2 PF08266.12 VBB33286.1 - 0.033 14.0 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Cadherin-like ThiF PF00899.21 VBB33287.1 - 3.2e-66 223.2 0.0 5.3e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family DnaJ PF00226.31 VBB33287.1 - 2.7e-19 69.0 0.4 5.6e-19 68.0 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain UAE_UbL PF14732.6 VBB33287.1 - 7.1e-18 65.0 0.3 2.4e-17 63.3 0.3 2.0 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 VBB33287.1 - 3.8e-07 30.3 4.6 0.00076 19.5 0.0 3.2 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 VBB33287.1 - 0.01 16.3 0.1 0.031 14.7 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding TM_helix PF05552.12 VBB33287.1 - 0.11 12.4 1.6 0.27 11.2 1.6 1.6 1 0 0 1 1 1 0 Conserved TM helix TUDOR PF00567.24 VBB33289.1 - 1.3e-42 144.7 0.1 8.6e-18 64.5 0.0 3.4 3 0 0 3 3 3 3 Tudor domain SMN PF06003.12 VBB33289.1 - 2.2e-05 23.9 0.1 0.017 14.4 0.0 3.2 3 0 0 3 3 3 2 Survival motor neuron protein (SMN) Agenet PF05641.12 VBB33289.1 - 0.021 15.3 0.5 22 5.6 0.0 3.5 3 0 0 3 3 3 0 Agenet domain DUF4537 PF15057.6 VBB33289.1 - 0.16 12.0 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) 7tm_1 PF00001.21 VBB33290.1 - 5.5e-08 32.5 23.7 9.7e-08 31.6 23.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SH3_1 PF00018.28 VBB33291.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 SH3 domain DUF1768 PF08719.11 VBB33292.1 - 1.5e-23 83.8 0.6 2.3e-23 83.2 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) CortBP2 PF09727.9 VBB33292.1 - 0.0021 18.0 0.6 0.004 17.1 0.6 1.4 1 0 0 1 1 1 1 Cortactin-binding protein-2 DDE_Tnp_IS240 PF13610.6 VBB33292.1 - 0.0034 17.6 0.2 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 DDE domain BRE1 PF08647.11 VBB33292.1 - 0.016 15.3 2.1 0.044 13.8 2.1 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 VBB33292.1 - 0.02 15.1 1.3 0.02 15.1 1.3 2.2 2 0 0 2 2 2 0 Haemolysin XhlA HMMR_C PF15908.5 VBB33292.1 - 0.77 10.0 5.6 0.22 11.8 2.1 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF1071 PF06378.11 VBB33293.1 - 0.0022 17.6 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1071) DUF1180 PF06679.12 VBB33294.1 - 0.065 13.7 0.2 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CLIP1_ZNF PF16641.5 VBB33297.1 - 1.2e-16 60.1 17.8 1.8e-08 34.1 5.2 2.3 2 0 0 2 2 2 2 CLIP1 zinc knuckle CENP-F_leu_zip PF10473.9 VBB33297.1 - 0.014 15.4 7.0 0.014 15.4 7.0 4.1 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 VBB33297.1 - 0.029 14.9 8.9 0.029 14.9 8.9 4.8 3 2 1 4 4 4 0 Apg6 coiled-coil region ERM PF00769.19 VBB33297.1 - 0.25 11.1 36.6 0.23 11.2 11.1 3.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family zf-CCHC_4 PF14392.6 VBB33297.1 - 0.38 10.5 3.7 3 7.6 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle MYO10_CC PF16735.5 VBB33297.1 - 1.3 9.2 16.6 3 8.0 1.6 4.6 3 1 1 4 4 4 0 Unconventional myosin-X coiled coil domain DUF1192 PF06698.11 VBB33297.1 - 2.3 8.3 13.7 6.3 6.9 1.6 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 VBB33297.1 - 7.9 6.0 34.9 0.43 10.1 2.1 4.4 1 1 4 5 5 5 0 HAUS augmin-like complex subunit 3 MFS_1_like PF12832.7 VBB33298.1 - 5.7e-48 163.7 10.8 7.7e-48 163.3 10.8 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 VBB33298.1 - 7e-11 41.6 20.9 2.3e-10 40.0 16.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 VBB33298.1 - 7.2e-06 25.2 5.7 7.2e-06 25.2 5.7 2.2 3 0 0 3 3 3 1 Nucleoside H+ symporter MFS_3 PF05977.13 VBB33298.1 - 5.3e-05 21.8 0.4 8.4e-05 21.2 0.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector LacY_symp PF01306.19 VBB33298.1 - 0.0037 16.1 9.7 0.12 11.1 0.1 2.1 2 0 0 2 2 2 2 LacY proton/sugar symporter DUF2873 PF11395.8 VBB33298.1 - 0.051 13.4 0.6 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) zf-C4 PF00105.18 VBB33299.1 - 3.3e-08 33.9 0.2 6.5e-08 32.9 0.1 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) tRNA-synt_2 PF00152.20 VBB33299.1 - 0.37 9.8 2.5 0.89 8.6 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) DUF3560 PF12083.8 VBB33300.1 - 0.059 13.5 0.3 0.17 12.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) AstA PF04958.12 VBB33300.1 - 0.29 9.6 1.6 31 3.0 0.0 3.2 1 1 3 4 4 4 0 Arginine N-succinyltransferase beta subunit zf-C4 PF00105.18 VBB33301.1 - 7.6e-30 103.2 10.6 1.5e-29 102.2 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) WH2 PF02205.20 VBB33302.1 - 2.6e-31 106.5 8.6 9.7e-10 38.0 0.3 4.9 4 0 0 4 4 4 4 WH2 motif zf-HC5HC2H_2 PF13832.6 VBB33303.1 - 1.7e-34 118.3 9.2 1.7e-34 118.3 9.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 VBB33303.1 - 2.4e-24 85.4 6.6 2.4e-24 85.4 6.6 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 VBB33303.1 - 6.6e-16 57.6 4.0 6.6e-16 57.6 4.0 3.4 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 VBB33303.1 - 1e-15 58.5 1.5 1.6e-15 57.9 1.2 1.4 1 1 1 2 2 2 1 Enhancer of polycomb-like PHD PF00628.29 VBB33303.1 - 2.2e-09 37.0 30.5 3.5e-09 36.4 9.6 3.3 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.22 VBB33303.1 - 0.0069 16.2 5.7 0.0069 16.2 5.7 3.7 3 2 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 VBB33303.1 - 0.012 15.9 7.7 0.012 15.9 7.7 3.0 3 0 0 3 3 3 0 RING-like domain C1_2 PF03107.16 VBB33303.1 - 0.014 15.7 2.8 0.014 15.7 2.8 3.7 3 1 0 3 3 3 0 C1 domain Rad21_Rec8_N PF04825.13 VBB33304.1 - 1.1e-39 135.0 0.1 2e-39 134.1 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 VBB33304.1 - 7.7e-19 66.7 0.1 3.1e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 VBB33304.1 - 0.0035 17.3 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 Segregation and condensation protein ScpA EF-hand_7 PF13499.6 VBB33305.1 - 1.1e-07 32.2 1.0 2.1e-07 31.3 1.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB33305.1 - 1.8e-05 24.3 2.7 0.027 14.4 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 VBB33305.1 - 0.00012 21.4 1.1 0.028 14.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 VBB33305.1 - 0.0069 16.3 0.5 0.66 10.0 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 VBB33305.1 - 0.016 15.0 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB33305.1 - 0.026 14.9 6.7 1.2 9.4 0.0 2.9 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 VBB33305.1 - 0.034 13.6 0.8 0.065 12.8 0.1 1.8 2 0 0 2 2 2 0 EF hand SNARE PF05739.19 VBB33306.1 - 9.3e-17 60.8 1.8 1.1e-16 60.6 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 VBB33306.1 - 4e-07 29.9 9.6 5e-06 26.3 9.6 2.1 1 1 0 1 1 1 1 Syntaxin Syntaxin-5_N PF11416.8 VBB33306.1 - 0.00073 18.7 0.0 0.0019 17.3 0.0 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain BLOC1_2 PF10046.9 VBB33306.1 - 0.037 14.3 7.5 0.8 10.0 1.6 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 VBB33306.1 - 0.17 12.4 6.9 0.26 11.8 0.4 2.8 2 2 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 VBB33306.1 - 2.1 8.4 8.6 13 5.9 0.9 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Nup_retrotrp_bd PF10599.9 VBB33306.1 - 3 8.5 6.3 28 5.4 0.0 2.6 2 0 0 2 2 2 0 Retro-transposon transporting motif UPF0242 PF06785.11 VBB33306.1 - 7.3 6.7 15.5 2.3 8.3 3.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus zf-A20 PF01754.16 VBB33308.1 - 1.1e-12 47.6 6.2 1.1e-12 47.6 6.2 2.3 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 VBB33308.1 - 9e-09 35.4 7.6 9e-09 35.4 7.6 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger zf-C5HC2 PF02928.16 VBB33308.1 - 0.054 13.9 5.9 0.076 13.4 3.8 2.3 3 0 0 3 3 3 0 C5HC2 zinc finger RhoGEF PF00621.20 VBB33309.1 - 2.4e-36 125.7 0.7 4.1e-36 124.9 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.31 VBB33309.1 - 1.1e-16 60.9 0.2 3.2e-16 59.4 0.1 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB33309.1 - 3e-09 36.6 0.7 6.1e-09 35.6 0.2 1.8 2 0 0 2 2 2 1 CAMSAP CH domain CDC24 PF06395.11 VBB33309.1 - 2.3e-05 24.6 0.1 7.2e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 CDC24 Calponin Kelch_1 PF01344.25 VBB33310.1 - 3.2e-88 289.1 25.3 5.1e-17 61.2 0.3 6.3 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 VBB33310.1 - 5.9e-36 122.7 1.2 1.2e-35 121.6 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 VBB33310.1 - 7.6e-36 121.2 5.5 9e-07 29.0 0.1 6.5 2 2 4 6 6 6 5 Kelch motif BTB PF00651.31 VBB33310.1 - 1.6e-33 115.3 0.5 2.8e-33 114.4 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 VBB33310.1 - 5.6e-32 108.5 7.6 4.8e-06 26.3 0.0 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 VBB33310.1 - 9.6e-23 80.0 15.3 0.00081 19.6 0.4 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 VBB33310.1 - 3.2e-22 78.3 5.8 5.8e-05 23.0 0.1 6.3 2 2 3 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 VBB33310.1 - 3.2e-07 30.2 5.8 1.3 9.1 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Glu_cyclase_2 PF05096.12 VBB33310.1 - 0.0019 17.7 0.0 0.32 10.4 0.0 2.4 1 1 1 2 2 2 1 Glutamine cyclotransferase PQQ_3 PF13570.6 VBB33310.1 - 0.042 14.3 15.3 0.64 10.6 0.2 5.6 6 0 0 6 6 6 0 PQQ-like domain DUF3342 PF11822.8 VBB33310.1 - 0.076 13.2 1.3 2.8 8.2 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) DUF684 PF05075.14 VBB33310.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF684) PK PF00224.21 VBB33313.1 - 3.2e-83 279.5 1.0 3.7e-83 279.3 1.0 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 VBB33313.1 - 6.5e-08 32.0 0.1 8.5e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GHMP_kinases_C PF08544.13 VBB33314.1 - 8.3e-16 58.1 0.1 3.8e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 VBB33314.1 - 1.7e-13 50.6 1.7 3e-13 49.8 0.8 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 VBB33314.1 - 1.4e-07 31.0 0.1 2.5e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DBINO PF13892.6 VBB33314.1 - 0.095 13.1 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA-binding domain DUF4187 PF13821.6 VBB33315.1 - 0.09 12.6 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) EnY2 PF10163.9 VBB33315.1 - 0.12 12.7 0.9 0.81 10.1 0.1 2.6 2 2 0 2 2 2 0 Transcription factor e(y)2 CX9C PF16860.5 VBB33315.1 - 0.39 10.8 3.2 0.54 10.3 1.2 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Kunitz_BPTI PF00014.23 VBB33316.1 - 2.3e-73 242.3 35.5 2.8e-15 56.3 2.7 5.5 5 0 0 5 5 5 5 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 VBB33316.1 - 1e-28 99.4 50.9 6.3e-11 42.5 7.0 4.9 4 0 0 4 4 4 4 Lustrin, cysteine-rich repeated domain RRM_7 PF16367.5 VBB33317.1 - 0.0065 16.6 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif DUF229 PF02995.17 VBB33318.1 - 2.3e-54 184.8 3.0 6.4e-54 183.4 3.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 VBB33318.1 - 5.5e-05 22.7 0.0 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 Sulfatase CG-1 PF03859.16 VBB33318.1 - 0.063 13.1 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 CG-1 domain Urm1 PF09138.11 VBB33318.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Meis_PKNOX_N PF16493.5 VBB33320.1 - 1.4e-07 31.7 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 DUF3446 PF11928.8 VBB33320.1 - 0.0013 18.9 0.2 0.0013 18.9 0.2 1.8 2 1 0 2 2 2 1 Early growth response N-terminal domain Myosin_head PF00063.21 VBB33320.1 - 0.065 11.4 0.0 0.081 11.1 0.0 1.0 1 0 0 1 1 1 0 Myosin head (motor domain) WD40 PF00400.32 VBB33322.1 - 3.3e-05 24.6 8.8 0.0062 17.4 0.9 4.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Vps52 PF04129.12 VBB33325.1 - 7.8e-08 31.5 0.4 7.8e-08 31.5 0.4 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 VBB33325.1 - 0.00032 19.3 0.6 0.00052 18.6 0.5 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF4901 PF16244.5 VBB33325.1 - 0.011 15.1 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) C2 PF00168.30 VBB33326.1 - 8.2e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain zf-met PF12874.7 VBB33326.1 - 0.15 12.5 0.2 0.31 11.5 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type JmjC PF02373.22 VBB33327.1 - 2.5e-29 102.0 0.9 2.5e-29 102.0 0.9 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase TPR_1 PF00515.28 VBB33327.1 - 1.5e-14 53.1 1.8 0.00013 21.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33327.1 - 1.3e-08 34.3 5.1 0.00029 20.7 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB33327.1 - 3.2e-07 30.3 0.8 0.089 13.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB33327.1 - 1.1e-05 25.9 0.5 0.037 14.7 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB33327.1 - 2e-05 24.8 2.4 0.073 13.4 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33327.1 - 0.0035 18.0 0.3 0.54 11.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33327.1 - 0.0055 16.8 4.8 3.2 8.2 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 VBB33327.1 - 0.01 15.5 1.5 4 7.2 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 VBB33327.1 - 0.027 15.0 1.8 0.41 11.2 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 VBB33327.1 - 0.029 14.5 0.2 0.1 12.8 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 VBB33327.1 - 0.17 12.6 0.5 21 6.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 VBB33327.1 - 0.19 11.9 1.6 57 4.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat I-set PF07679.16 VBB33328.1 - 1.8e-41 140.1 0.0 4.7e-21 74.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB33328.1 - 3e-38 130.3 0.0 7.8e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain An_peroxidase PF03098.15 VBB33328.1 - 2.8e-26 92.2 0.2 4.8e-26 91.4 0.0 1.4 2 0 0 2 2 2 1 Animal haem peroxidase ig PF00047.25 VBB33328.1 - 4.3e-21 74.9 0.0 2.6e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 VBB33328.1 - 1.4e-19 70.2 0.0 1.3e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 VBB33328.1 - 1.6e-09 37.9 0.6 0.0056 16.9 0.0 4.2 2 2 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB33328.1 - 3.2e-09 36.7 0.0 0.0058 16.7 0.0 3.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 VBB33328.1 - 0.00012 22.5 0.0 0.035 14.5 0.0 2.7 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 VBB33328.1 - 0.00013 22.0 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 2 C17orf99 Ig domain LRRNT PF01462.18 VBB33328.1 - 0.00017 21.1 4.3 0.00017 21.1 4.3 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 VBB33328.1 - 0.00031 20.4 0.4 0.00099 18.8 0.1 2.0 2 0 0 2 2 2 1 Leucine rich repeat Ig_4 PF16680.5 VBB33328.1 - 0.0012 19.0 0.0 0.53 10.6 0.0 2.9 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain DUF1320 PF07030.12 VBB33328.1 - 0.068 13.3 0.1 7 6.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) BiPBP_C PF06832.12 VBB33328.1 - 0.072 13.1 0.0 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family LRR_4 PF12799.7 VBB33328.1 - 0.086 13.3 0.4 0.086 13.3 0.4 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ANAPC4_WD40 PF12894.7 VBB33329.1 - 8.3e-07 29.2 0.0 0.00037 20.7 0.0 3.5 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 VBB33329.1 - 9e-05 23.2 3.4 0.43 11.5 0.0 3.9 4 1 0 4 4 4 2 WD domain, G-beta repeat Tubulin PF00091.25 VBB33330.1 - 4.8e-45 154.2 0.0 7.1e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB33330.1 - 3.1e-10 40.3 0.0 4.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 VBB33330.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin like DUF3602 PF12223.8 VBB33330.1 - 0.027 15.0 0.0 0.055 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Tubulin PF00091.25 VBB33331.1 - 4.2e-70 236.0 0.0 7.2e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 VBB33331.1 - 1.1e-40 138.6 0.1 1.7e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 VBB33331.1 - 8.3e-07 29.3 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 VBB33331.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like DUF4041 PF13250.6 VBB33332.1 - 0.041 13.7 0.8 0.75 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Snf7 PF03357.21 VBB33333.1 - 1.4e-10 41.1 10.1 1.4e-10 41.1 10.1 1.5 1 1 1 2 2 2 1 Snf7 DUF3708 PF12501.8 VBB33333.1 - 0.041 13.7 1.6 0.054 13.3 1.6 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter IZUMO PF15005.6 VBB33333.1 - 0.18 12.3 1.5 0.28 11.7 1.5 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DMSP_lyase PF16867.5 VBB33333.1 - 0.23 11.1 0.8 0.36 10.5 0.4 1.5 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase T2SSM PF04612.12 VBB33333.1 - 0.59 10.2 9.3 0.25 11.4 1.4 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Ins_P5_2-kin PF06090.12 VBB33334.1 - 3.8e-55 187.6 0.1 5e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF3786 PF12654.7 VBB33334.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) AAR2 PF05282.11 VBB33336.1 - 2.8e-91 306.6 0.0 3.4e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein RNHCP PF12647.7 VBB33337.1 - 0.019 15.0 0.2 0.026 14.5 0.2 1.2 1 0 0 1 1 1 0 RNHCP domain Zn_ribbon_SprT PF17283.2 VBB33337.1 - 0.97 9.4 6.9 2.1 8.3 5.3 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Nup54 PF13874.6 VBB33338.1 - 0.0017 18.4 1.7 0.0021 18.2 0.6 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF5376 PF17346.2 VBB33338.1 - 0.019 15.3 2.2 0.26 11.6 0.0 3.3 3 2 1 4 4 4 0 Family of unknown function (DUF5376) Syntaxin_2 PF14523.6 VBB33338.1 - 0.077 13.4 5.5 1.4 9.3 1.8 3.1 2 1 0 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.9 VBB33339.1 - 0.0019 18.4 4.5 0.3 11.4 0.2 2.4 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 PTRF_SDPR PF15237.6 VBB33339.1 - 0.0029 17.3 1.9 0.0043 16.7 1.7 1.4 1 1 0 1 1 1 1 PTRF/SDPR family MIF4G_like_2 PF09090.11 VBB33339.1 - 0.026 14.0 0.6 0.042 13.3 0.6 1.3 1 0 0 1 1 1 0 MIF4G like DASH_Duo1 PF08651.10 VBB33339.1 - 0.034 13.9 2.3 0.23 11.2 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 TerD PF02342.18 VBB33339.1 - 0.045 13.2 0.9 0.07 12.6 0.4 1.5 1 1 1 2 2 2 0 TerD domain CdvA PF18822.1 VBB33339.1 - 0.045 13.6 2.6 0.78 9.6 0.1 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 VBB33339.1 - 0.055 13.4 6.6 1.5 8.8 0.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit Toxin_trans PF07952.12 VBB33339.1 - 0.056 12.5 2.2 0.077 12.1 2.1 1.3 1 1 0 1 1 1 0 Clostridium neurotoxin, Translocation domain GAS PF13851.6 VBB33339.1 - 0.077 12.3 5.3 0.26 10.6 5.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SOAR PF16533.5 VBB33339.1 - 0.11 12.5 0.7 13 5.8 0.1 2.4 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF1366 PF07104.11 VBB33339.1 - 0.13 11.9 1.3 0.22 11.2 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1366) RmuC PF02646.16 VBB33339.1 - 0.13 11.3 3.4 1.6 7.8 0.4 2.0 2 0 0 2 2 2 0 RmuC family zf-C4H2 PF10146.9 VBB33339.1 - 0.17 12.2 4.1 0.65 10.3 4.1 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein TP_methylase PF00590.20 VBB33339.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases MCR_C PF04609.12 VBB33339.1 - 0.21 10.7 1.6 4.1 6.4 1.6 2.0 1 1 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C CorA PF01544.18 VBB33339.1 - 0.21 10.8 2.0 0.28 10.4 2.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 VBB33339.1 - 0.29 11.4 2.1 6.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 VBB33339.1 - 1.1 9.8 7.1 11 6.5 1.7 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Uso1_p115_C PF04871.13 VBB33339.1 - 1.2 9.5 7.9 4.4 7.7 1.3 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MH2 PF03166.14 VBB33340.1 - 5.1e-10 39.9 0.0 7.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 MH2 domain PHO4 PF01384.20 VBB33341.1 - 1.2e-100 336.9 19.0 3.9e-60 203.7 1.2 2.7 3 0 0 3 3 3 2 Phosphate transporter family HTH_IclR PF09339.10 VBB33341.1 - 0.23 11.3 1.5 0.75 9.6 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain CPP1-like PF11833.8 VBB33341.1 - 0.94 9.1 7.8 0.79 9.4 2.4 2.5 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pkinase PF00069.25 VBB33342.1 - 5.9e-23 81.6 0.0 7.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33342.1 - 3.2e-10 39.7 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB33342.1 - 4.2e-05 22.5 0.0 4.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB33342.1 - 0.00065 19.7 0.0 0.0037 17.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 VBB33342.1 - 0.059 13.0 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 VBB33342.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Caprin-1_dimer PF18293.1 VBB33343.1 - 0.00059 20.3 2.0 0.0018 18.7 0.2 2.6 1 1 2 3 3 3 1 Caprin-1 dimerization domain Syntaxin_2 PF14523.6 VBB33343.1 - 0.023 15.0 10.2 0.023 15.0 10.2 2.8 2 1 1 3 3 3 0 Syntaxin-like protein TPR_2 PF07719.17 VBB33344.1 - 6.9e-25 85.1 44.1 0.00016 21.5 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 VBB33344.1 - 1.1e-19 70.5 35.4 2.6e-05 24.4 0.3 8.1 6 1 3 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33344.1 - 2.7e-15 55.2 48.4 0.039 14.2 0.1 12.4 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33344.1 - 1.2e-13 50.2 55.0 0.0026 17.5 0.1 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 VBB33344.1 - 7.9e-11 41.5 26.1 3.5e-06 26.6 0.1 7.8 7 1 1 8 8 8 4 TPR repeat TPR_7 PF13176.6 VBB33344.1 - 6.7e-09 35.2 24.6 0.13 12.4 0.3 9.9 9 2 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33344.1 - 2.2e-07 31.1 15.7 0.26 12.2 0.0 9.2 10 1 2 12 12 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 VBB33344.1 - 2.8e-07 31.1 14.9 0.053 14.2 0.7 6.1 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33344.1 - 1.2e-06 28.9 26.1 0.016 15.7 0.1 8.6 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 VBB33344.1 - 5.6e-06 26.4 5.6 0.081 13.1 0.0 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 VBB33344.1 - 1.7e-05 24.9 22.2 0.09 13.2 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB33344.1 - 0.00076 19.5 5.2 0.015 15.4 0.2 4.6 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 VBB33344.1 - 0.0054 16.9 30.9 0.93 9.8 1.1 7.6 5 3 3 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 CRAL_TRIO_2 PF13716.6 VBB33344.1 - 0.014 15.5 0.6 0.056 13.6 0.6 2.0 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TPR_10 PF13374.6 VBB33344.1 - 0.022 14.6 34.6 0.62 10.0 0.1 8.6 11 0 0 11 11 10 0 Tetratricopeptide repeat DUF3261 PF11659.8 VBB33344.1 - 0.023 14.6 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) TPR_4 PF07721.14 VBB33344.1 - 0.05 14.2 0.0 0.72 10.7 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat ATP13 PF12921.7 VBB33344.1 - 0.073 12.9 1.4 1.3 8.9 0.1 3.3 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_6 PF13174.6 VBB33344.1 - 0.59 10.9 24.5 3.4 8.5 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 VBB33344.1 - 1.3 9.1 14.1 4.3 7.5 0.1 5.7 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Peptidase_M13_N PF05649.13 VBB33345.1 - 1.1e-54 186.6 6.4 1.2e-43 150.3 0.0 2.6 2 1 1 3 3 3 2 Peptidase family M13 Peptidase_M13 PF01431.21 VBB33345.1 - 4.9e-51 173.3 0.5 8.4e-51 172.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M4 PF01447.18 VBB33345.1 - 0.023 15.2 3.2 0.07 13.6 3.2 1.8 1 1 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain RIH_assoc PF08454.11 VBB33345.1 - 0.028 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 RyR and IP3R Homology associated MIF4G_like PF09088.11 VBB33346.1 - 1.1e-33 116.6 4.4 1.9e-33 115.9 1.2 2.4 2 1 1 3 3 3 1 MIF4G like MIF4G PF02854.19 VBB33346.1 - 8.2e-13 48.5 0.2 9.3e-07 28.7 0.0 2.5 1 1 1 2 2 2 2 MIF4G domain MIF4G_like_2 PF09090.11 VBB33346.1 - 4.4e-09 36.2 0.1 4.4e-09 36.2 0.1 2.3 3 0 0 3 3 3 1 MIF4G like Spectrin PF00435.21 VBB33347.1 - 9.6e-137 447.1 108.2 1.7e-19 70.3 1.5 12.2 12 0 0 12 12 12 12 Spectrin repeat CH PF00307.31 VBB33347.1 - 5.7e-26 90.8 2.5 4.5e-25 87.9 0.0 3.4 3 0 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB33347.1 - 2.8e-06 27.0 0.0 7.6e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain SH3_9 PF14604.6 VBB33347.1 - 3.2e-06 26.9 0.2 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 VBB33347.1 - 6e-06 25.8 0.1 1.8e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB33347.1 - 1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 VBB33347.1 - 8.6e-05 22.7 0.1 0.00032 20.9 0.1 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 VBB33347.1 - 0.0067 16.5 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 SH3 domain PMC2NT PF08066.12 VBB33347.1 - 4.2 8.1 16.4 8.8 7.1 0.3 5.7 6 0 0 6 6 6 0 PMC2NT (NUC016) domain FRQ PF09421.10 VBB33349.1 - 0.32 9.0 11.4 0.4 8.7 11.4 1.0 1 0 0 1 1 1 0 Frequency clock protein SDA1 PF05285.12 VBB33349.1 - 2.3 7.6 22.3 3.1 7.1 22.3 1.1 1 0 0 1 1 1 0 SDA1 DUF1619 PF07773.11 VBB33350.1 - 2.5e-10 40.8 0.1 4.5e-10 40.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1619) His_binding PF02098.16 VBB33350.1 - 0.011 15.8 0.1 0.024 14.7 0.0 1.6 1 1 0 1 1 1 0 Tick histamine binding protein EFF-AFF PF14884.6 VBB33352.1 - 1.8e-152 508.5 3.8 2.5e-152 508.1 3.8 1.1 1 0 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen PRC PF05239.16 VBB33352.1 - 0.18 11.9 0.3 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 PRC-barrel domain zf-CCHC PF00098.23 VBB33354.1 - 3.6e-38 127.9 48.0 4.1e-08 32.9 4.6 5.6 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 VBB33354.1 - 7.7e-09 35.2 29.3 0.0048 16.6 0.9 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 VBB33354.1 - 3.1e-08 33.5 35.0 0.0082 16.1 1.1 5.3 2 2 3 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 VBB33354.1 - 1.3e-07 31.3 31.7 0.014 15.2 1.8 5.3 4 1 1 5 5 5 4 Zinc knuckle Coagulin PF02035.15 VBB33354.1 - 8.5e-07 29.0 12.6 0.29 11.0 0.1 5.1 1 1 4 5 5 5 4 Coagulin zf-CCHC_5 PF14787.6 VBB33354.1 - 0.00015 21.4 26.9 0.14 11.9 0.9 5.3 5 0 0 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 VBB33354.1 - 0.00038 20.2 42.5 0.019 14.8 1.7 5.4 5 0 0 5 5 5 4 Zinc knuckle Fer4_20 PF14691.6 VBB33354.1 - 0.15 11.8 0.0 0.15 11.8 0.0 4.0 4 1 1 5 5 5 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster RNase_T PF00929.24 VBB33355.1 - 4.9e-13 50.0 0.0 7.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 VBB33355.1 - 0.0029 17.3 0.0 0.0067 16.1 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease DUF755 PF05501.11 VBB33355.1 - 1.9 8.8 9.6 3.1 8.1 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF1794 PF08768.11 VBB33356.1 - 1.6e-31 109.2 0.0 1.9e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) DUF229 PF02995.17 VBB33358.1 - 1.2e-109 367.2 0.7 1.5e-109 366.9 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 VBB33358.1 - 0.00035 20.1 0.0 0.00078 18.9 0.0 1.4 1 1 0 1 1 1 1 Sulfatase EFF-AFF PF14884.6 VBB33359.1 - 3.1e-65 220.4 7.9 1.1e-64 218.6 7.9 1.7 1 1 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen Myosin_head PF00063.21 VBB33360.1 - 8.5e-73 245.7 11.3 1.7e-72 244.7 11.3 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 VBB33360.1 - 2.3e-14 53.8 3.1 1.4e-13 51.3 0.0 3.7 4 0 0 4 4 4 1 MyTH4 domain IQ PF00612.27 VBB33360.1 - 5.3e-08 32.0 1.2 0.0018 17.9 0.3 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF3439 PF11921.8 VBB33360.1 - 0.057 13.4 3.6 0.12 12.3 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 VBB33362.1 - 1.2e-05 24.9 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33362.1 - 0.0019 17.6 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 VBB33363.1 - 8e-10 38.9 0.6 1.7e-08 34.7 0.1 2.5 2 0 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.10 VBB33363.1 - 0.025 15.0 1.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding IL12p40_C PF10420.9 VBB33363.1 - 0.2 12.2 3.0 7.1 7.2 0.4 2.6 1 1 1 2 2 2 0 Cytokine interleukin-12p40 C-terminus GPP34 PF05719.11 VBB33364.1 - 4.5e-18 66.0 0.1 6e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Arf PF00025.21 VBB33365.1 - 1.2e-37 129.1 0.0 1.4e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 VBB33365.1 - 9.4e-14 51.7 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 VBB33365.1 - 7.1e-13 48.5 0.0 8.9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 VBB33365.1 - 1.4e-10 40.9 0.1 1.4e-06 27.7 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 VBB33365.1 - 2.9e-10 39.9 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 VBB33365.1 - 2.9e-09 36.6 0.1 3.4e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB33365.1 - 1.2e-06 28.5 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 VBB33365.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 Thymidylate kinase Pox_A32 PF04665.12 VBB33365.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein GTP_EFTU PF00009.27 VBB33365.1 - 0.099 12.2 0.0 14 5.2 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 VBB33365.1 - 0.13 11.8 0.2 0.5 9.9 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 VBB33365.1 - 0.15 11.9 0.0 5.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 VBB33365.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 VBB33365.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 VBB33365.1 - 0.19 12.3 0.1 0.33 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain NUDIX PF00293.28 VBB33366.1 - 1.3e-17 64.1 1.7 2.4e-17 63.2 1.7 1.4 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.21 VBB33366.1 - 5.1e-06 27.0 0.1 1.7e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 VBB33366.1 - 2.3e-05 24.3 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 TRAM domain SDA1 PF05285.12 VBB33367.1 - 1.6e-05 24.5 28.3 2.3e-05 24.0 17.9 2.1 2 0 0 2 2 2 2 SDA1 Cwf_Cwc_15 PF04889.12 VBB33367.1 - 0.0015 18.3 4.2 0.0015 18.3 4.2 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 VBB33367.1 - 0.27 10.5 37.6 0.012 15.0 20.6 2.1 2 0 0 2 2 2 0 BUD22 Zip PF02535.22 VBB33367.1 - 1.1 8.5 14.5 0.071 12.3 7.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter NOA36 PF06524.12 VBB33367.1 - 1.5 8.1 22.3 0.17 11.2 10.2 2.3 2 0 0 2 2 2 0 NOA36 protein Strabismus PF06638.11 VBB33367.1 - 2 7.0 13.2 0.14 10.8 7.2 1.9 2 0 0 2 2 2 0 Strabismus protein SAPS PF04499.15 VBB33367.1 - 4.7 5.9 20.8 0.13 11.0 11.7 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PNISR PF15996.5 VBB33367.1 - 5.4 7.2 31.6 2.8 8.2 21.3 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM76 PF16046.5 VBB33367.1 - 6.6 6.0 27.1 1.4 8.2 16.5 2.2 2 0 0 2 2 2 0 FAM76 protein SpoIIIAH PF12685.7 VBB33367.1 - 8.4 6.2 33.6 0.24 11.2 22.6 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein FAM60A PF15396.6 VBB33367.1 - 9.3 6.2 25.5 9.9 6.1 3.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A FANCI_HD2 PF14680.6 VBB33368.1 - 0.41 9.9 4.7 0.72 9.1 4.7 1.5 1 0 0 1 1 1 0 FANCI helical domain 2 Homeodomain PF00046.29 VBB33370.1 - 9.6e-20 70.2 2.6 9.6e-20 70.2 2.6 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 VBB33370.1 - 0.0045 16.9 1.7 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain DNA_pol3_tau_5 PF12170.8 VBB33372.1 - 0.031 14.3 0.2 0.04 14.0 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha DUF5320 PF17253.2 VBB33372.1 - 0.072 14.2 0.7 0.11 13.6 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF2621 PF11084.8 VBB33372.1 - 0.13 12.2 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) ZapB PF06005.12 VBB33372.1 - 0.24 11.9 3.6 0.39 11.2 3.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB PAS_4 PF08448.10 VBB33375.1 - 0.0009 19.5 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 VBB33375.1 - 0.0074 16.5 0.1 0.021 15.0 0.1 1.8 1 1 0 1 1 1 1 PAS domain PAS PF00989.25 VBB33375.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.6 1 1 0 1 1 1 0 PAS fold LIM PF00412.22 VBB33376.1 - 1.8e-14 53.7 19.1 4.9e-10 39.5 1.0 5.7 6 1 1 7 7 7 2 LIM domain PET PF06297.14 VBB33377.1 - 1.4e-31 108.6 0.6 6.4e-31 106.5 0.0 1.9 1 1 1 2 2 2 1 PET Domain LIM PF00412.22 VBB33377.1 - 2.3e-09 37.4 5.6 4.3e-09 36.5 5.6 1.5 1 0 0 1 1 1 1 LIM domain VATC PF18716.1 VBB33377.1 - 0.15 12.0 5.1 1.8 8.5 1.3 2.5 2 0 0 2 2 2 0 Vms1-associating treble clef domain Ras PF00071.22 VBB33379.1 - 1.3e-53 180.9 1.2 1.6e-53 180.6 1.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB33379.1 - 6.8e-27 94.1 0.3 1.3e-26 93.1 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB33379.1 - 5.8e-08 32.4 0.1 7.9e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 VBB33379.1 - 0.0022 17.9 0.5 0.16 11.9 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 VBB33379.1 - 0.005 16.4 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 VBB33379.1 - 0.021 14.4 0.0 0.089 12.3 0.0 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 VBB33379.1 - 0.042 13.9 0.0 0.13 12.4 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF2757 PF10955.8 VBB33379.1 - 0.058 13.6 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) SRPRB PF09439.10 VBB33379.1 - 0.14 11.6 0.2 0.55 9.6 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 VBB33379.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain GCFC PF07842.12 VBB33380.1 - 4e-81 272.6 12.2 5.6e-81 272.2 12.2 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 VBB33380.1 - 3.1e-18 66.1 3.0 3.1e-18 66.1 3.0 2.4 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 VBB33380.1 - 3.3e-16 58.9 0.6 6.4e-16 58.0 0.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 VBB33380.1 - 0.00026 21.0 0.4 0.00026 21.0 0.4 2.7 2 0 0 2 2 2 1 G-patch domain FAM178 PF14816.6 VBB33380.1 - 0.16 10.9 4.3 0.27 10.2 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 FUSC PF04632.12 VBB33380.1 - 1.5 7.3 4.6 2.9 6.3 4.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 VBB33380.1 - 3.1 8.0 9.9 6.4 7.0 9.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AP2 PF00847.20 VBB33381.1 - 0.15 12.3 0.1 0.22 11.8 0.1 1.2 1 0 0 1 1 1 0 AP2 domain DUF3439 PF11921.8 VBB33382.1 - 0.0051 16.8 10.3 0.0051 16.8 10.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Homeodomain PF00046.29 VBB33383.1 - 3.5e-15 55.6 0.1 5.5e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 VBB33383.1 - 1.6e-08 34.7 1.6 3.5e-08 33.6 1.6 1.5 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 VBB33383.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain NAD_binding_1 PF00175.21 VBB33383.1 - 0.063 13.9 0.1 9.5 6.9 0.1 2.2 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain bZIP_2 PF07716.15 VBB33384.1 - 5.6e-12 45.5 13.0 1.1e-11 44.6 13.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 VBB33384.1 - 1.8e-05 24.8 11.3 3.9e-05 23.7 11.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 VBB33384.1 - 0.015 15.8 8.2 0.032 14.7 8.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.18 VBB33384.1 - 0.022 15.0 1.7 0.057 13.7 1.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mto2_bdg PF12808.7 VBB33384.1 - 0.5 10.7 13.7 4 7.8 13.7 2.2 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FYVE PF01363.21 VBB33385.1 - 1.6e-17 63.4 9.2 6.4e-17 61.5 9.2 2.1 1 1 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 VBB33385.1 - 1.6e-11 43.7 1.9 1.6e-11 43.7 1.9 2.0 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 VBB33385.1 - 0.082 13.2 0.2 0.082 13.2 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE_2 PF02318.16 VBB33385.1 - 2.4 8.4 11.7 0.37 11.0 3.3 3.5 3 0 0 3 3 3 0 FYVE-type zinc finger DZF PF07528.14 VBB33386.1 - 1.8e-43 149.0 0.1 2.3e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 DZF domain UQ_con PF00179.26 VBB33387.1 - 1.2e-41 141.7 0.0 1.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB33387.1 - 0.077 12.7 0.1 0.35 10.6 0.1 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B LSM PF01423.22 VBB33388.1 - 3.1e-20 71.6 0.1 3.7e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 VBB33388.1 - 3e-06 27.3 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 VBB33388.1 - 0.0047 17.0 0.1 0.0056 16.7 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain UBA2_C PF16195.5 VBB33389.1 - 0.0068 17.1 0.2 0.0068 17.1 0.2 1.9 3 0 0 3 3 3 1 SUMO-activating enzyme subunit 2 C-terminus I-set PF07679.16 VBB33390.1 - 3e-17 62.4 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB33390.1 - 1.8e-09 38.0 0.1 3.6e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 VBB33390.1 - 8.9e-05 22.8 0.1 0.0058 16.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 VBB33390.1 - 0.00083 19.5 0.0 0.0027 17.9 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.6 VBB33390.1 - 0.091 12.9 0.2 26 5.2 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat BACK PF07707.15 VBB33391.1 - 2.9e-10 40.1 0.3 5.6e-10 39.3 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 VBB33391.1 - 0.034 14.4 0.2 0.08 13.2 0.1 1.7 2 0 0 2 2 2 0 BTB/POZ domain PH PF00169.29 VBB33392.1 - 1e-09 38.8 1.3 2.5e-09 37.6 1.3 1.7 1 0 0 1 1 1 1 PH domain Caskin-Pro-rich PF16907.5 VBB33392.1 - 1.1 9.9 7.3 0.68 10.5 3.2 2.6 2 0 0 2 2 2 0 Proline rich region of Caskin proteins PH_11 PF15413.6 VBB33392.1 - 4.6 7.7 8.6 0.17 12.4 2.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain UNC-93 PF05978.16 VBB33393.1 - 2.1e-49 167.2 17.9 2.1e-49 167.2 17.9 3.3 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 VBB33393.1 - 1.9e-17 63.2 50.2 3.5e-14 52.5 34.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX_2 PF13869.6 VBB33394.1 - 3e-53 180.2 0.0 3.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Acatn PF13000.7 VBB33395.1 - 2.9e-60 204.3 2.5 3.6e-60 204.0 2.5 1.1 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 MFS_2 PF13347.6 VBB33395.1 - 0.01 14.4 3.5 0.27 9.7 3.6 2.5 1 1 1 2 2 2 0 MFS/sugar transport protein MFS_1 PF07690.16 VBB33395.1 - 0.017 14.0 8.6 0.036 13.0 8.6 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Glyco_transf_92 PF01697.27 VBB33396.1 - 1.5e-41 142.8 5.7 2.5e-41 142.1 5.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 VBB33396.1 - 0.0018 18.7 0.0 0.006 17.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Telomere_reg-2 PF10193.9 VBB33397.1 - 4.7e-24 84.9 0.5 1.1e-22 80.6 0.1 2.6 3 0 0 3 3 3 1 Telomere length regulation protein Ly-6_related PF06579.12 VBB33398.1 - 3e-30 105.0 0.2 3.7e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein RhoGEF PF00621.20 VBB33401.1 - 8.9e-36 123.8 1.5 1.6e-35 123.0 1.5 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 VBB33401.1 - 4.2e-12 45.7 0.1 8e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB33401.1 - 1.3e-08 34.3 0.1 2.3e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 VBB33401.1 - 5.7e-08 32.3 0.0 1.5e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 VBB33401.1 - 0.0015 19.0 0.0 0.0066 16.9 0.0 2.1 2 0 0 2 2 2 1 PH domain SH3_16 PF18348.1 VBB33401.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF5362 PF17319.2 VBB33402.1 - 0.021 14.7 2.4 0.025 14.4 2.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5362) DUF4134 PF13572.6 VBB33402.1 - 0.036 14.4 2.7 3.7 7.9 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4134) PsbN PF02468.15 VBB33402.1 - 0.27 11.1 1.0 0.44 10.4 1.0 1.5 1 1 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) ETF PF01012.21 VBB33403.1 - 4.1e-43 147.4 0.6 4.9e-43 147.1 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Tmemb_185A PF10269.9 VBB33404.1 - 2.6e-06 27.3 8.6 1.1e-05 25.3 8.6 1.8 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF202 PF02656.15 VBB33404.1 - 0.078 13.4 0.4 0.078 13.4 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DPM3 PF08285.11 VBB33404.1 - 0.73 10.1 7.3 0.38 11.0 0.8 2.1 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RNase_T PF00929.24 VBB33405.1 - 1.4e-29 103.8 0.5 3.4e-29 102.5 0.0 1.9 2 1 0 2 2 2 1 Exonuclease SAP PF02037.27 VBB33405.1 - 1.4e-06 27.9 0.1 3.3e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 SAP domain Pkinase PF00069.25 VBB33406.1 - 2.6e-59 200.7 0.0 3.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33406.1 - 1e-23 84.0 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB33406.1 - 2.1e-07 30.6 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB33406.1 - 0.00015 20.7 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 VBB33406.1 - 0.003 17.1 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 VBB33406.1 - 0.0034 16.8 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 VBB33406.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Homeodomain PF00046.29 VBB33408.1 - 3.4e-20 71.6 1.3 5.4e-20 71.0 1.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB33408.1 - 6.3e-06 26.0 0.1 1.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Myosin_tail_1 PF01576.19 VBB33409.1 - 1.5e-128 430.4 249.8 6.2e-112 375.3 219.9 2.3 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.21 VBB33409.1 - 1.6e-43 149.0 0.1 1.6e-43 149.0 0.1 3.0 2 0 0 2 2 1 1 Myosin head (motor domain) DUF745 PF05335.13 VBB33409.1 - 0.0003 20.6 17.3 0.0003 20.6 17.3 10.1 1 1 10 13 13 12 1 Protein of unknown function (DUF745) BST2 PF16716.5 VBB33409.1 - 0.0049 17.4 9.8 0.0049 17.4 9.8 15.6 4 3 12 17 17 17 3 Bone marrow stromal antigen 2 ATG16 PF08614.11 VBB33409.1 - 0.0054 17.0 39.7 0.0054 17.0 39.7 9.6 1 1 9 10 10 8 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 VBB33409.1 - 0.0086 16.6 18.7 0.0086 16.6 18.7 12.3 3 2 8 11 11 8 1 Apg6 coiled-coil region BRE1 PF08647.11 VBB33409.1 - 0.0095 16.0 14.2 0.0095 16.0 14.2 15.1 2 1 14 16 16 15 6 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 VBB33409.1 - 0.015 15.9 3.3 0.015 15.9 3.3 14.1 3 2 8 13 13 11 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 VBB33409.1 - 0.017 14.7 216.8 0.041 13.5 33.4 7.4 1 1 5 6 6 6 0 Intermediate filament protein TFA2_Winged_2 PF18121.1 VBB33409.1 - 0.033 13.9 0.5 0.34 10.6 0.1 3.1 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 DUF812 PF05667.11 VBB33409.1 - 1.5 7.6 219.6 0.16 10.8 49.0 7.1 1 1 5 6 6 6 0 Protein of unknown function (DUF812) DUF4554 PF15091.6 VBB33410.1 - 1.7 7.5 7.3 2 7.2 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Presenilin PF01080.17 VBB33410.1 - 4.3 6.0 9.6 7 5.3 9.6 1.4 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 VBB33410.1 - 8 6.5 17.8 11 6.0 17.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_S8e PF01201.22 VBB33411.1 - 1.4e-48 164.5 3.4 1.9e-48 164.1 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Kdo PF06293.14 VBB33412.1 - 1.4e-11 44.1 0.0 2.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 VBB33412.1 - 1.3e-09 37.9 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 VBB33412.1 - 2e-09 37.2 0.0 3.3e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33412.1 - 2e-05 24.0 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB33412.1 - 5.5e-05 23.2 0.0 0.0039 17.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 VBB33412.1 - 0.00094 18.6 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 VBB33412.1 - 0.064 12.0 0.1 0.18 10.5 0.0 1.5 1 1 1 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 VBB33412.1 - 0.094 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF812 PF05667.11 VBB33419.1 - 1.7e-50 172.6 27.6 4.3e-36 125.0 25.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF812) YliH PF10799.8 VBB33419.1 - 0.011 15.7 1.2 2.1 8.3 0.2 2.7 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) TRIQK PF15168.6 VBB33419.1 - 0.16 11.9 1.8 0.38 10.7 0.2 2.4 1 1 1 2 2 2 0 Triple QxxK/R motif-containing protein family EGF PF00008.27 VBB33420.1 - 0.046 14.0 3.0 0.071 13.4 3.0 1.3 1 0 0 1 1 1 0 EGF-like domain HLH PF00010.26 VBB33421.1 - 2.7e-16 59.2 2.4 5.8e-16 58.2 2.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3231 PF11553.8 VBB33421.1 - 0.055 13.1 0.0 0.43 10.2 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3231) YojJ PF10372.9 VBB33423.1 - 0.15 12.2 0.3 0.15 12.2 0.3 2.5 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus LZ3wCH PF18517.1 VBB33423.1 - 0.22 11.6 1.9 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Leucine zipper with capping helix domain V_ATPase_I PF01496.19 VBB33423.1 - 0.43 8.4 7.7 0.56 8.0 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FCH PF00611.23 VBB33423.1 - 1.2 9.4 9.7 0.069 13.4 2.8 2.7 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 VBB33423.1 - 1.5 8.1 7.9 2.4 7.4 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 VBB33423.1 - 2.2 8.1 9.7 1.6 8.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 VBB33423.1 - 2.6 8.1 19.2 0.5 10.4 6.6 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tox-GHH PF15636.6 VBB33426.1 - 1.2e-05 25.2 0.1 1.9e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin PCI PF01399.27 VBB33426.1 - 0.033 14.7 0.1 0.056 14.0 0.1 1.5 1 0 0 1 1 1 0 PCI domain FAD_binding_5 PF00941.21 VBB33426.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase SLH PF00395.20 VBB33426.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 S-layer homology domain Patched PF02460.18 VBB33427.1 - 1.6e-32 112.5 5.3 2e-32 112.3 5.3 1.0 1 0 0 1 1 1 1 Patched family AAA_28 PF13521.6 VBB33428.1 - 1.1e-21 77.8 0.0 2.1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 VBB33428.1 - 0.0041 16.8 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 VBB33428.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DRE2_N PF16803.5 VBB33428.1 - 0.091 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus LSDAT_euk PF18139.1 VBB33429.1 - 1.1e-110 369.3 0.0 1.5e-110 368.8 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 VBB33429.1 - 3.2e-16 59.2 0.0 7e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ank_2 PF12796.7 VBB33429.1 - 0.094 13.3 0.4 2.1 9.0 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Proteasome PF00227.26 VBB33430.1 - 7.1e-23 81.1 0.0 8.3e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit UPF0149 PF03695.13 VBB33430.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Dus PF01207.17 VBB33431.1 - 5.6e-67 226.0 0.0 7.9e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 VBB33431.1 - 0.0067 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 VBB33431.1 - 0.033 13.6 0.1 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase HTH_25 PF13413.6 VBB33431.1 - 0.41 10.6 1.9 0.64 9.9 0.7 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Cofilin_ADF PF00241.20 VBB33433.1 - 5.8e-25 87.5 0.8 8.5e-19 67.5 0.4 2.4 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Tweety PF04906.13 VBB33435.1 - 0.029 13.0 0.1 0.043 12.5 0.1 1.1 1 0 0 1 1 1 0 Tweety TMEM154 PF15102.6 VBB33435.1 - 0.056 13.3 1.1 0.17 11.8 0.2 2.1 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 VBB33435.1 - 0.074 13.9 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 VBB33435.1 - 0.083 13.3 1.9 1 9.9 0.1 2.5 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF98 PF01947.16 VBB33436.1 - 0.083 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase SNF PF00209.18 VBB33438.1 - 3.7e-171 570.4 42.5 4.3e-171 570.2 42.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Presenilin PF01080.17 VBB33439.1 - 0.11 11.3 6.0 0.12 11.1 6.0 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 VBB33439.1 - 0.2 10.6 5.5 0.24 10.3 5.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 VBB33439.1 - 4.3 6.5 5.2 5 6.3 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.19 VBB33439.1 - 5.9 5.7 9.2 6.8 5.5 9.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TB2_DP1_HVA22 PF03134.19 VBB33440.1 - 4.8e-22 77.7 0.3 8.7e-22 76.9 0.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Aa_trans PF01490.18 VBB33442.1 - 2.1e-67 227.7 19.6 2.7e-67 227.3 19.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 VBB33442.1 - 0.042 12.7 21.8 0.022 13.6 0.8 3.6 3 0 0 3 3 3 0 Spore germination protein Peptidase_M22 PF00814.25 VBB33443.1 - 2.5e-85 286.5 0.0 4e-85 285.8 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family Tmemb_55A PF09788.9 VBB33444.1 - 4.9e-57 192.8 19.1 5.9e-57 192.6 19.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A CK_II_beta PF01214.18 VBB33444.1 - 0.028 14.2 2.4 0.078 12.8 2.4 1.8 1 0 0 1 1 1 0 Casein kinase II regulatory subunit dsrm PF00035.26 VBB33444.1 - 0.17 12.6 2.7 0.68 10.7 0.2 2.4 1 1 1 2 2 2 0 Double-stranded RNA binding motif IBR PF01485.21 VBB33444.1 - 1.4 9.2 24.9 4 7.7 2.7 4.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain Integrase_H2C2 PF17921.1 VBB33444.1 - 2.8 8.1 9.5 1.6 8.9 0.8 2.7 2 1 1 3 3 3 0 Integrase zinc binding domain DUF4674 PF15719.5 VBB33444.1 - 6.6 6.7 13.1 0.29 11.2 3.4 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4674) Prominin PF05478.11 VBB33445.1 - 1.9e-35 122.1 15.2 1.9e-35 122.1 15.2 1.5 1 1 1 2 2 2 1 Prominin DUF5084 PF16894.5 VBB33445.1 - 0.13 12.7 0.9 0.48 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) ApoLp-III PF07464.11 VBB33445.1 - 0.18 11.9 7.7 0.32 11.1 0.9 3.6 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) AATF-Che1 PF13339.6 VBB33445.1 - 0.52 11.0 2.7 25 5.6 2.6 3.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor TPR_MLP1_2 PF07926.12 VBB33445.1 - 1.2 9.3 9.1 0.051 13.6 0.9 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 VBB33445.1 - 1.2 8.9 9.8 4.1 7.2 0.5 3.8 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF2203 PF09969.9 VBB33445.1 - 1.5 9.5 4.4 42 4.9 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Cob_adeno_trans PF01923.18 VBB33445.1 - 4.6 7.4 5.9 11 6.2 0.5 3.3 2 1 1 3 3 3 0 Cobalamin adenosyltransferase fn3 PF00041.21 VBB33446.1 - 0.016 15.6 0.0 0.075 13.4 0.0 2.1 2 1 0 2 2 2 0 Fibronectin type III domain DUF1664 PF07889.12 VBB33448.1 - 0.25 11.4 19.0 0.45 10.6 10.5 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Rimk_N PF18030.1 VBB33448.1 - 0.68 10.4 3.4 2.9 8.3 0.8 3.1 2 2 2 4 4 4 0 RimK PreATP-grasp domain DUF2407 PF10302.9 VBB33448.1 - 2.6 8.7 8.2 1.4 9.5 3.7 2.7 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Peptidase_M16_M PF16187.5 VBB33449.1 - 3e-82 276.1 7.5 3.3e-82 276.0 5.2 2.0 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 VBB33449.1 - 1.5e-10 41.4 0.8 5.2e-09 36.4 0.2 2.9 4 0 0 4 4 4 1 Peptidase M16 inactive domain Fibrillarin PF01269.17 VBB33451.1 - 3.9e-107 356.5 0.0 4.8e-107 356.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 VBB33451.1 - 0.00078 19.2 0.1 0.0015 18.3 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 VBB33451.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C4 PF00105.18 VBB33452.1 - 5.8e-31 106.8 14.2 1.7e-30 105.3 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Bestrophin PF01062.21 VBB33453.1 - 2.6e-92 309.4 10.6 2.6e-92 309.4 10.6 1.9 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel DUF4300 PF14133.6 VBB33453.1 - 0.0075 16.0 0.1 0.0075 16.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4300) DUF4694 PF15765.5 VBB33453.1 - 2.9 7.9 11.9 1.4 8.9 0.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4694) DUF1757 PF08560.10 VBB33455.1 - 9.1e-53 178.3 0.0 1.1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) TRP_2 PF08344.11 VBB33456.1 - 8.6e-27 93.1 4.8 2.2e-26 91.8 4.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 VBB33456.1 - 5.1e-14 52.6 4.3 3.2e-08 34.0 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB33456.1 - 3.7e-11 43.3 0.3 0.00027 21.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB33456.1 - 1.1e-09 38.3 3.0 0.0015 18.8 0.3 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB33456.1 - 1.7e-08 34.0 3.8 0.0024 18.2 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 VBB33456.1 - 4.6e-07 30.0 5.5 0.03 14.8 0.3 3.5 2 1 1 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 VBB33456.1 - 0.076 13.0 0.4 0.076 13.0 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) LRR19-TM PF15176.6 VBB33456.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Glyco_hydro_38N PF01074.22 VBB33457.1 - 1.3e-63 215.0 1.1 1.6e-63 214.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 VBB33457.1 - 1.6e-18 66.6 1.5 3.9e-18 65.4 0.9 1.9 2 0 0 2 2 2 1 Alpha mannosidase middle domain MFS_1 PF07690.16 VBB33459.1 - 1.4e-37 129.5 33.2 1.4e-37 129.5 33.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM234 PF10639.9 VBB33459.1 - 0.052 13.6 4.2 4.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF4212 PF13937.6 VBB33459.1 - 7.7 7.0 17.5 1.1 9.7 0.6 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) 7tm_1 PF00001.21 VBB33460.1 - 1e-29 103.7 21.0 1.3e-29 103.4 21.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Anp1 PF03452.14 VBB33461.1 - 0.00038 20.0 0.0 0.16 11.3 0.1 2.5 1 1 1 2 2 2 2 Anp1 DivIVA PF05103.13 VBB33461.1 - 0.066 13.3 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 DivIVA protein Anp1 PF03452.14 VBB33462.1 - 0.0001 21.8 0.1 0.16 11.4 0.0 3.1 3 0 0 3 3 3 3 Anp1 2OG-FeII_Oxy_3 PF13640.6 VBB33462.1 - 0.00019 22.2 0.1 0.00039 21.2 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Caprin-1_dimer PF18293.1 VBB33463.1 - 2.6e-08 34.4 1.6 4.6e-08 33.5 0.9 1.7 1 1 0 1 1 1 1 Caprin-1 dimerization domain V-set PF07686.17 VBB33464.1 - 3.8e-16 59.2 1.1 1.3e-09 38.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 VBB33464.1 - 4.2e-15 55.6 0.1 2.8e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB33464.1 - 5.1e-14 52.6 0.5 3.1e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 VBB33464.1 - 2.3e-13 50.1 0.8 2e-05 24.7 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 VBB33464.1 - 2.5e-08 34.1 0.5 0.00061 20.1 0.3 2.5 1 1 1 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.11 VBB33464.1 - 6.2e-06 26.2 3.3 0.001 19.1 2.3 2.2 1 1 1 2 2 2 2 CD47 immunoglobulin-like domain Ig_4 PF16680.5 VBB33464.1 - 8.6e-06 25.9 1.4 0.0098 16.1 0.1 3.4 2 2 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 VBB33464.1 - 0.00011 21.7 0.1 0.53 9.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 VBB33464.1 - 0.0032 17.2 0.4 0.68 9.8 0.0 2.3 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 C1-set PF07654.15 VBB33464.1 - 0.0035 17.7 0.3 0.08 13.3 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 VBB33464.1 - 0.0057 17.0 2.4 3.3 8.2 0.7 3.3 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 VBB33464.1 - 0.0063 16.6 0.1 0.6 10.2 0.1 3.0 2 1 0 2 2 2 1 Izumo-like Immunoglobulin domain zf-H2C2_2 PF13465.6 VBB33466.1 - 3.2e-05 24.1 14.5 8.7e-05 22.8 6.5 9.0 9 1 1 10 10 10 3 Zinc-finger double domain zf-C2H2 PF00096.26 VBB33466.1 - 0.00032 21.0 92.1 0.014 15.8 4.8 9.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type Kunitz_BPTI PF00014.23 VBB33467.1 - 3.5e-71 235.3 77.7 1e-17 64.1 5.0 7.0 7 0 0 7 7 7 5 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 VBB33467.1 - 1.3e-29 102.2 137.0 2.1e-08 34.4 4.7 11.2 11 0 0 11 11 11 8 Lustrin, cysteine-rich repeated domain EB PF01683.18 VBB33467.1 - 7.7e-10 38.9 7.8 7.7e-10 38.9 7.8 9.1 6 4 2 8 8 8 2 EB module Cytochrom_C552 PF02335.15 VBB33469.1 - 0.0082 15.1 0.5 0.011 14.7 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c552 Atg14 PF10186.9 VBB33469.1 - 0.011 14.9 5.0 0.013 14.6 4.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FtsX_ECD PF18075.1 VBB33469.1 - 0.3 11.8 6.3 4.8 7.9 1.0 2.5 2 1 0 2 2 2 0 FtsX extracellular domain DUF5339 PF17274.2 VBB33469.1 - 0.4 11.6 3.2 3.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Fez1 PF06818.15 VBB33469.1 - 0.89 10.0 9.7 1.4 9.3 4.3 2.1 1 1 1 2 2 2 0 Fez1 zf-C4H2 PF10146.9 VBB33469.1 - 1.1 9.5 7.6 0.29 11.4 2.6 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 VBB33469.1 - 2.3 8.9 7.9 8.5 7.1 0.1 3.6 3 1 0 3 3 3 0 SlyX Spc24 PF08286.11 VBB33469.1 - 4 7.7 12.6 4.9 7.4 0.5 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Fzo_mitofusin PF04799.13 VBB33469.1 - 4.7 6.7 8.6 0.42 10.2 1.5 2.6 1 1 2 3 3 3 0 fzo-like conserved region DUF1192 PF06698.11 VBB33469.1 - 7.1 6.8 9.4 25 5.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Motile_Sperm PF00635.26 VBB33470.1 - 9.8e-26 89.7 0.0 1.1e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CPSF_A PF03178.15 VBB33471.1 - 7.4e-58 196.4 0.0 8.4e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region CBFD_NFYB_HMF PF00808.23 VBB33472.1 - 2.5e-18 66.1 2.0 2.8e-18 66.0 0.6 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 VBB33472.1 - 2.4e-12 47.3 1.8 3.9e-12 46.6 1.6 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 VBB33472.1 - 0.006 16.7 0.5 0.015 15.4 0.3 1.8 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) DUF2990 PF11693.8 VBB33472.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Ins145_P3_rec PF08709.11 VBB33473.1 - 2.6e-75 252.3 0.0 1.1e-73 247.0 0.0 2.5 1 1 2 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 VBB33473.1 - 1e-37 129.8 0.9 1.4e-33 116.3 0.2 2.5 2 0 0 2 2 2 2 MIR domain Mucin_bdg PF03272.13 VBB33473.1 - 0.03 14.3 0.3 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Putative mucin or carbohydrate-binding module AA_permease PF00324.21 VBB33474.1 - 5.4e-27 94.5 8.9 6.9e-27 94.2 8.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 VBB33474.1 - 3.7e-06 26.3 0.0 8.6e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Amino acid permease N-terminal HSF_DNA-bind PF00447.17 VBB33475.1 - 2.5e-28 98.5 0.7 5.5e-28 97.4 0.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Leu_zip PF15294.6 VBB33475.1 - 0.00071 19.2 1.6 0.0014 18.2 1.6 1.4 1 0 0 1 1 1 1 Leucine zipper ZapB PF06005.12 VBB33475.1 - 0.0092 16.4 6.2 0.029 14.8 6.2 1.8 1 0 0 1 1 1 1 Cell division protein ZapB Tup_N PF08581.10 VBB33475.1 - 0.049 13.9 3.2 0.13 12.6 3.2 1.6 1 0 0 1 1 1 0 Tup N-terminal BRE1 PF08647.11 VBB33475.1 - 0.051 13.7 3.2 0.086 12.9 2.1 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase YscO PF07321.12 VBB33475.1 - 0.068 13.1 3.0 0.14 12.1 3.0 1.5 1 0 0 1 1 1 0 Type III secretion protein YscO TRAF_BIRC3_bd PF16673.5 VBB33475.1 - 0.097 12.5 2.3 0.3 10.9 2.3 1.9 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain GHD PF17834.1 VBB33475.1 - 0.11 12.6 0.2 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Ets PF00178.22 VBB33475.1 - 0.11 12.9 0.1 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 Ets-domain YabA PF06156.13 VBB33475.1 - 0.24 12.0 3.0 0.63 10.7 3.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA GIT_CC PF16559.5 VBB33475.1 - 0.5 10.3 4.6 1.9 8.4 4.6 2.0 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 VBB33475.1 - 3.3 7.8 5.8 1.9 8.6 1.4 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Btz PF09405.10 VBB33476.1 - 3.3e-16 59.7 16.0 3.3e-16 59.7 16.0 4.2 2 2 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ntox5 PF15543.6 VBB33476.1 - 0.013 15.3 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial toxin 5 zf-C4 PF00105.18 VBB33477.1 - 7.9e-29 99.9 15.1 1.6e-28 99.0 15.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB33477.1 - 1e-15 57.9 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Xpo1 PF08389.12 VBB33478.1 - 1.3e-06 28.6 1.3 1.3e-06 28.6 1.3 2.1 2 1 0 2 2 2 1 Exportin 1-like protein MOR2-PAG1_C PF14225.6 VBB33478.1 - 0.015 15.2 1.3 0.047 13.6 0.3 2.2 2 1 0 2 2 2 0 Cell morphogenesis C-terminal IBN_N PF03810.19 VBB33478.1 - 0.05 13.5 0.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain Methyltransf_3 PF01596.17 VBB33479.1 - 1.5e-46 158.3 0.3 1.8e-46 158.0 0.3 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 VBB33479.1 - 3.3e-08 34.5 0.0 5.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB33479.1 - 2e-05 24.4 0.0 3.1e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB33479.1 - 8.8e-05 23.1 0.0 0.00029 21.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 VBB33479.1 - 0.0019 17.6 0.0 0.0038 16.6 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 VBB33479.1 - 0.012 16.3 0.0 0.024 15.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 VBB33479.1 - 0.017 15.8 0.0 0.25 12.0 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain PAP_assoc PF03828.19 VBB33480.1 - 2.3e-13 50.1 0.2 4.8e-13 49.1 0.1 1.6 2 0 0 2 2 2 1 Cid1 family poly A polymerase Nrap_D2 PF17403.2 VBB33480.1 - 0.012 15.3 0.0 0.44 10.3 0.0 2.1 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain Pkinase PF00069.25 VBB33483.1 - 4.5e-20 72.1 0.0 5.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33483.1 - 8.7e-10 38.3 0.0 1.5e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB33483.1 - 2.2e-06 26.8 0.1 5.9e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 VBB33483.1 - 0.0054 16.4 0.0 0.08 12.6 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PP1_inhibitor PF05361.12 VBB33483.1 - 0.1 12.6 0.3 0.24 11.4 0.2 1.6 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor zf-CCCH PF00642.24 VBB33484.1 - 3.6e-09 36.3 1.6 3.6e-09 36.3 1.6 1.8 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 VBB33484.1 - 1.3e-07 31.3 8.6 2.4e-07 30.5 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 VBB33484.1 - 1.9e-06 27.7 3.3 1.9e-06 27.7 3.3 1.9 2 0 0 2 2 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 VBB33484.1 - 1.1e-05 25.2 11.3 1.1e-05 25.2 11.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 VBB33484.1 - 1.1e-05 25.1 1.9 1.1e-05 25.1 1.9 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 VBB33484.1 - 2.4e-05 24.1 12.1 5.2e-05 23.0 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB33484.1 - 3.2e-05 23.8 13.2 6.1e-05 22.9 13.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB33484.1 - 4.9e-05 23.3 8.9 0.00011 22.1 8.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 VBB33484.1 - 0.00036 20.6 6.2 0.00036 20.6 6.2 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 VBB33484.1 - 0.00048 20.4 10.3 0.00048 20.4 10.3 1.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 VBB33484.1 - 0.0034 17.2 8.0 0.0065 16.3 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 VBB33484.1 - 0.038 14.2 10.9 0.1 12.8 10.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_8 PF18633.1 VBB33484.1 - 0.16 12.1 0.2 0.16 12.1 0.2 2.8 4 0 0 4 4 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 zf-Nse PF11789.8 VBB33484.1 - 0.48 10.3 8.1 0.34 10.8 6.0 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 VBB33484.1 - 1.2 9.7 7.4 0.11 13.0 2.3 2.0 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger CUE PF02845.16 VBB33486.1 - 2.5e-08 33.5 0.9 6.3e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 CUE domain zf-rbx1 PF12678.7 VBB33486.1 - 0.00048 20.4 1.0 0.0064 16.8 1.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 VBB33486.1 - 0.0075 16.6 2.6 0.024 14.9 1.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 VBB33486.1 - 0.064 13.1 0.8 0.064 13.1 0.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4685 PF15737.5 VBB33486.1 - 0.076 13.5 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) CDP-OH_P_transf PF01066.21 VBB33489.1 - 1.5e-13 51.3 0.3 1.5e-13 51.3 0.3 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase VIT1 PF01988.19 VBB33489.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.4 1 1 2 3 3 3 0 VIT family NAD_Gly3P_dh_N PF01210.23 VBB33490.1 - 4.6e-51 172.9 0.1 8.9e-51 172.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 VBB33490.1 - 2.5e-45 154.3 0.1 5.7e-45 153.1 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 VBB33490.1 - 9.7e-05 22.9 0.2 0.0077 16.8 0.0 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TSP_1 PF00090.19 VBB33492.1 - 2.9e-15 56.2 73.3 6.4e-05 23.1 2.6 8.2 7 2 0 7 7 7 5 Thrombospondin type 1 domain I-set PF07679.16 VBB33492.1 - 4.8e-10 39.4 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB33492.1 - 1.4e-09 38.4 0.0 5.3e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 VBB33492.1 - 7.2e-07 29.3 0.1 3.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 VBB33492.1 - 0.00012 22.3 0.0 0.00055 20.2 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 VBB33492.1 - 0.00034 21.0 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 VBB33492.1 - 0.0032 17.6 0.1 0.081 13.1 0.0 2.5 1 1 1 2 2 2 1 Immunoglobulin V-set domain An_peroxidase PF03098.15 VBB33493.1 - 3e-99 333.0 0.0 3.4e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase PAT1 PF09770.9 VBB33494.1 - 3.7 5.7 6.4 5.8 5.0 6.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TP6A_N PF04406.14 VBB33495.1 - 2.9e-14 52.8 0.1 5.2e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase AAA PF00004.29 VBB33496.1 - 1e-12 48.6 0.0 2.8e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB33496.1 - 1.4e-06 28.8 0.0 8.5e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 VBB33496.1 - 2.8e-06 27.4 0.0 6.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 VBB33496.1 - 2.9e-05 23.9 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 VBB33496.1 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 VBB33496.1 - 0.00026 21.2 0.1 0.00026 21.2 0.1 2.2 3 1 0 3 3 1 1 AAA domain AAA_22 PF13401.6 VBB33496.1 - 0.00032 21.0 0.4 0.016 15.4 0.2 3.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 VBB33496.1 - 0.00038 20.3 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 VBB33496.1 - 0.00046 20.7 0.2 0.002 18.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 VBB33496.1 - 0.00081 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 VBB33496.1 - 0.0011 19.0 0.0 0.074 13.0 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 VBB33496.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 VBB33496.1 - 0.0015 18.0 0.0 0.0048 16.4 0.0 1.8 2 0 0 2 2 1 1 PhoH-like protein AAA_24 PF13479.6 VBB33496.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 VBB33496.1 - 0.003 17.7 0.0 0.0097 16.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 VBB33496.1 - 0.0058 16.9 0.5 0.013 15.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 VBB33496.1 - 0.0084 15.6 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 VBB33496.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 VBB33496.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain TIP49 PF06068.13 VBB33496.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_6 PF12774.7 VBB33496.1 - 0.015 14.3 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 VBB33496.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 VBB33496.1 - 0.035 14.0 0.4 0.17 11.8 0.1 2.3 3 0 0 3 3 2 0 NACHT domain IPT PF01745.16 VBB33496.1 - 0.038 13.4 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Cytidylate_kin PF02224.18 VBB33496.1 - 0.045 13.5 1.0 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase ATPase PF06745.13 VBB33496.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 VBB33496.1 - 0.11 12.4 0.0 0.83 9.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 VBB33496.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Melibiase_2 PF16499.5 VBB33497.1 - 8.9e-133 441.8 6.1 1.1e-132 441.6 6.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 VBB33497.1 - 2e-08 34.2 0.0 8.7e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 VBB33497.1 - 1.6e-06 27.3 0.0 2.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 VBB33497.1 - 0.0038 17.4 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain TPT PF03151.16 VBB33499.1 - 5.4e-13 48.9 2.2 6.4e-13 48.7 2.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 VBB33499.1 - 2.4e-05 24.5 19.5 0.00013 22.1 4.6 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 VBB33499.1 - 0.0054 16.0 6.4 0.0055 16.0 5.9 1.3 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 VBB33499.1 - 0.0061 15.8 6.0 0.0093 15.2 5.9 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Tlr3_TMD PF17968.1 VBB33499.1 - 1.7 8.9 9.1 2.2 8.6 1.3 3.0 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain IPK PF03770.16 VBB33500.1 - 1.1e-47 162.5 0.1 1.7e-47 161.9 0.1 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase NUC153 PF08159.12 VBB33501.1 - 2e-10 40.3 0.1 4.1e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 NUC153 domain Ank_4 PF13637.6 VBB33502.1 - 1.3e-21 76.7 4.5 3.3e-09 37.1 0.2 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB33502.1 - 4e-20 72.2 3.5 2.6e-09 37.5 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB33502.1 - 2.4e-14 53.2 8.0 5.7e-08 32.9 0.4 3.6 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB33502.1 - 1.5e-12 46.5 7.2 0.0004 20.6 0.1 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 VBB33502.1 - 1e-09 38.4 13.9 0.00028 21.2 0.7 5.0 5 0 0 5 5 5 3 Ankyrin repeat DUF249 PF03158.13 VBB33502.1 - 0.0086 15.8 0.2 0.11 12.2 0.2 2.2 1 1 0 1 1 1 1 Multigene family 530 protein FAM176 PF14851.6 VBB33503.1 - 0.22 11.1 1.1 0.4 10.3 1.1 1.4 1 0 0 1 1 1 0 FAM176 family ANF_receptor PF01094.28 VBB33504.1 - 5.3e-23 81.7 0.2 6.1e-23 81.5 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ANAPC_CDC26 PF10471.9 VBB33504.1 - 0.006 17.4 0.1 0.013 16.3 0.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Peptidase_M28 PF04389.17 VBB33506.1 - 7.7e-20 71.4 0.0 1.8e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 VBB33506.1 - 5.9e-13 48.6 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.15 VBB33506.1 - 3.5e-12 46.5 0.8 7e-12 45.5 0.1 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Nicastrin PF05450.15 VBB33506.1 - 0.0012 18.4 0.1 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 Nicastrin Peptidase_M20 PF01546.28 VBB33506.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF3987 PF13148.6 VBB33507.1 - 0.1 11.6 0.7 0.13 11.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IF4E PF01652.18 VBB33508.1 - 1.8e-49 167.6 1.1 2.4e-49 167.2 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peroxin-3 PF04882.12 VBB33509.1 - 2.1e-14 53.4 0.3 5.1e-08 32.4 0.1 2.0 1 1 1 2 2 2 2 Peroxin-3 OAD_gamma PF04277.13 VBB33511.1 - 0.017 15.7 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Syndecan PF01034.20 VBB33511.1 - 0.018 14.9 2.1 0.035 14.0 2.1 1.6 1 1 0 1 1 1 0 Syndecan domain ECSCR PF15820.5 VBB33511.1 - 0.03 14.1 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 VBB33511.1 - 0.044 14.7 0.0 0.051 14.5 0.0 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.19 VBB33511.1 - 0.045 13.5 0.6 0.045 13.5 0.6 1.7 2 0 0 2 2 2 0 Vpu protein ODV-E18 PF10717.9 VBB33511.1 - 0.055 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PspB PF06667.12 VBB33511.1 - 0.089 12.9 0.3 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Phage shock protein B DUF1418 PF07214.12 VBB33511.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Epimerase PF01370.21 VBB33512.1 - 6.1e-21 75.0 0.0 9.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 VBB33512.1 - 4.5e-15 55.4 0.0 8.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 VBB33512.1 - 2.7e-10 39.8 0.0 7.6e-08 31.8 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 VBB33512.1 - 4.8e-10 39.6 0.0 8.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 VBB33512.1 - 6e-05 22.6 0.0 0.00065 19.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Coatomer_E PF04733.14 VBB33513.1 - 4.6e-95 318.4 11.5 5.4e-95 318.1 11.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 VBB33513.1 - 1e-07 32.4 10.2 0.00092 19.7 0.7 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33513.1 - 1.3e-05 24.9 4.3 0.0018 18.2 0.3 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33513.1 - 1.5e-05 25.1 5.4 0.01 16.0 0.1 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 VBB33513.1 - 0.00058 20.1 2.1 0.59 10.5 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 VBB33513.1 - 0.00082 20.0 8.6 0.091 13.6 0.4 4.0 3 1 1 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 VBB33513.1 - 0.0028 17.9 2.3 0.9 9.9 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB33513.1 - 0.0056 16.5 2.1 0.095 12.6 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33513.1 - 0.006 16.7 3.2 0.5 10.7 0.4 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 VBB33513.1 - 0.01 15.5 0.6 0.61 9.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 VBB33513.1 - 0.032 14.9 1.4 0.18 12.5 0.1 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat UPF0121 PF03661.13 VBB33513.1 - 0.035 13.5 0.2 0.052 12.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) TPR_11 PF13414.6 VBB33513.1 - 0.057 13.1 1.5 0.13 12.0 0.9 1.9 2 0 0 2 2 2 0 TPR repeat Bin3 PF06859.12 VBB33513.1 - 0.089 13.4 0.2 8 7.1 0.0 2.6 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) TPR_7 PF13176.6 VBB33513.1 - 0.096 12.8 2.0 5.9 7.2 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.8 VBB33513.1 - 0.11 12.4 3.4 1.4 8.8 0.1 3.1 2 1 0 2 2 2 0 YfdX protein TPR_1 PF00515.28 VBB33513.1 - 1.8 8.5 8.3 0.3 11.0 1.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HR1 PF02185.16 VBB33514.1 - 9.6e-12 44.9 1.8 9.6e-12 44.9 1.8 2.1 2 0 0 2 2 2 1 Hr1 repeat SH3_1 PF00018.28 VBB33514.1 - 8.8e-09 34.8 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB33514.1 - 2.5e-06 27.2 0.0 4.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Dynamitin PF04912.14 VBB33514.1 - 2.2e-05 24.0 0.5 0.00071 19.0 0.2 2.2 2 0 0 2 2 2 1 Dynamitin NPR2 PF06218.11 VBB33514.1 - 0.0092 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Nitrogen permease regulator 2 DUF1192 PF06698.11 VBB33514.1 - 0.03 14.4 1.8 0.074 13.1 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF2274 PF10038.9 VBB33514.1 - 0.043 14.3 0.4 5.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) SH3_3 PF08239.11 VBB33514.1 - 0.086 13.1 0.0 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain Uds1 PF15456.6 VBB33514.1 - 1.9 8.6 7.6 0.29 11.3 1.0 2.5 2 0 0 2 2 2 0 Up-regulated During Septation FliJ PF02050.16 VBB33514.1 - 2.2 8.5 14.3 0.27 11.5 1.7 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein rve PF00665.26 VBB33515.1 - 8.5e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain EF-hand_7 PF13499.6 VBB33517.1 - 8.5e-09 35.7 1.3 8.5e-09 35.7 1.3 2.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB33517.1 - 3.6e-07 29.6 0.9 0.00068 19.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 VBB33517.1 - 3.5e-05 23.1 0.1 0.14 11.8 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 VBB33517.1 - 0.00026 20.8 0.1 0.59 10.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB33517.1 - 0.012 15.1 0.1 2.8 7.6 0.0 3.1 2 0 0 2 2 2 0 EF hand WBP-1 PF11669.8 VBB33517.1 - 1.5 9.5 4.0 1.4 9.6 0.2 2.6 2 0 0 2 2 2 0 WW domain-binding protein 1 Tmemb_9 PF05434.11 VBB33517.1 - 8.2 6.3 9.1 23 4.9 5.4 2.7 2 0 0 2 2 2 0 TMEM9 SelK_SelG PF10961.8 VBB33518.1 - 6.1e-15 55.6 1.3 9.1e-15 55.1 1.3 1.3 1 0 0 1 1 1 1 Selenoprotein SelK_SelG zf-BED PF02892.15 VBB33519.1 - 1.5e-05 24.9 0.7 3.8e-05 23.6 0.7 1.7 1 0 0 1 1 1 1 BED zinc finger Cep57_CLD PF14073.6 VBB33519.1 - 0.06 13.4 0.2 0.06 13.4 0.2 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Trp_repressor PF01371.19 VBB33519.1 - 0.066 13.4 0.1 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Trp repressor protein DUF641 PF04859.12 VBB33519.1 - 0.081 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Med4 PF10018.9 VBB33519.1 - 0.084 12.5 2.6 0.066 12.9 0.7 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 YpsA PF06908.11 VBB33520.1 - 0.028 14.4 0.2 0.036 14.1 0.2 1.1 1 0 0 1 1 1 0 YspA SLOG family Collagen PF01391.18 VBB33521.1 - 1.2e-13 50.5 51.5 7.7e-08 32.0 17.1 2.5 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Motile_Sperm PF00635.26 VBB33522.1 - 6.6e-23 80.6 0.0 7.5e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Cytochrom_B561 PF03188.16 VBB33523.1 - 1.6e-40 138.4 6.5 1.6e-40 138.4 6.5 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4131 PF13567.6 VBB33523.1 - 0.023 14.4 2.7 0.84 9.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DDDD PF10161.9 VBB33523.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein RNase_Zc3h12a PF11977.8 VBB33526.1 - 7.4e-14 51.8 0.1 1.4e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 VBB33526.1 - 7.4e-05 22.4 0.3 0.00011 21.8 0.3 1.2 1 0 0 1 1 1 1 Protein-only RNase P Motile_Sperm PF00635.26 VBB33528.1 - 3.6e-07 30.0 0.1 7.4e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain I_LWEQ PF01608.17 VBB33528.1 - 0.023 15.0 11.0 0.053 13.8 11.0 1.6 1 0 0 1 1 1 0 I/LWEQ domain LRS4 PF10422.9 VBB33528.1 - 0.039 13.5 9.3 0.057 13.0 9.3 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ArnB_C PF18677.1 VBB33528.1 - 0.082 13.0 6.9 0.19 11.8 6.9 1.7 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain TolA_bind_tri PF16331.5 VBB33528.1 - 0.71 10.0 12.8 0.9 9.7 10.1 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation S_4TM PF18159.1 VBB33529.1 - 0.18 11.1 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Y_phosphatase PF00102.27 VBB33530.1 - 2.6e-67 226.8 2.3 3.4e-67 226.5 2.3 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB33530.1 - 0.0033 17.4 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 VBB33530.1 - 0.034 13.9 1.2 0.034 13.9 1.2 2.4 2 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 VBB33531.1 - 1e-07 31.5 0.1 2.6e-05 23.6 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 LIP PF03583.14 VBB33531.1 - 0.013 14.9 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.16 VBB33531.1 - 0.052 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 VBB33531.1 - 0.055 13.1 0.1 0.07 12.8 0.1 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0258 PF06789.12 VBB33531.1 - 0.068 13.3 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DLH PF01738.18 VBB33531.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family zf-C3HC4_5 PF17121.5 VBB33531.1 - 0.12 12.3 1.4 0.2 11.6 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_1 PF00561.20 VBB33531.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 VBB33531.1 - 0.24 10.9 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family CYYR1 PF10873.8 VBB33532.1 - 0.011 16.2 8.2 0.018 15.5 8.2 1.4 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 CD34_antigen PF06365.12 VBB33532.1 - 0.012 15.2 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family NrfD PF03916.14 VBB33532.1 - 0.033 13.8 0.3 0.045 13.4 0.3 1.1 1 0 0 1 1 1 0 Polysulphide reductase, NrfD MscL PF01741.18 VBB33532.1 - 0.038 14.3 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF4834 PF16118.5 VBB33532.1 - 0.42 11.6 1.6 0.46 11.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) His_Phos_1 PF00300.22 VBB33533.1 - 1.3e-15 57.6 0.0 1.7e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Patatin PF01734.22 VBB33534.1 - 4.1e-17 63.0 1.2 2.9e-16 60.3 1.2 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Ground-like PF04155.18 VBB33537.1 - 4.7e-22 78.4 1.5 1.2e-21 77.2 1.5 1.7 1 0 0 1 1 1 1 Ground-like domain zf-CCCH PF00642.24 VBB33538.1 - 2.7e-17 62.2 3.3 4.8e-09 35.9 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB33538.1 - 2.5e-11 43.2 5.2 1.6e-05 24.8 0.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB33538.1 - 3.1e-08 33.2 3.2 8.9e-05 22.2 0.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 VBB33538.1 - 6.7e-05 23.2 2.8 0.032 14.7 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 VBB33538.1 - 0.012 16.3 1.3 2.6 8.8 0.2 2.4 2 0 0 2 2 2 0 Torus domain oligo_HPY PF08352.12 VBB33538.1 - 0.97 10.0 5.0 7.4 7.2 0.1 2.9 3 0 0 3 3 3 0 Oligopeptide/dipeptide transporter, C-terminal region Neur_chan_LBD PF02931.23 VBB33541.1 - 4.5e-38 130.9 0.9 6.1e-38 130.4 0.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Cyclin_N PF00134.23 VBB33542.1 - 2.7e-10 40.1 0.2 2.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 VBB33542.1 - 0.023 14.7 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C PF02984.19 VBB33542.1 - 0.51 10.4 0.0 0.51 10.4 0.0 2.5 3 0 0 3 3 3 0 Cyclin, C-terminal domain Snf7 PF03357.21 VBB33543.1 - 2.9e-24 85.6 11.8 5.5e-24 84.7 11.8 1.5 1 0 0 1 1 1 1 Snf7 HORMA PF02301.18 VBB33543.1 - 2.6e-08 33.7 0.4 7.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 HORMA domain HSBP1 PF06825.12 VBB33543.1 - 0.2 11.5 5.4 3.6 7.5 1.4 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tugs PF17840.1 VBB33543.1 - 0.37 11.0 2.7 1.2 9.4 0.5 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain AAA_23 PF13476.6 VBB33543.1 - 1.7 9.1 5.3 2.7 8.5 5.3 1.4 1 0 0 1 1 1 0 AAA domain Amino_oxidase PF01593.24 VBB33545.1 - 3.9e-14 52.8 0.0 5.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 VBB33545.1 - 5.5e-14 52.3 0.1 1.6e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 VBB33545.1 - 8.2e-10 38.8 0.1 2.2e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 VBB33545.1 - 2.9e-06 26.9 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 VBB33545.1 - 7.1e-06 25.5 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 VBB33545.1 - 2.4e-05 24.1 0.5 4e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 VBB33545.1 - 3.9e-05 22.6 0.4 5.8e-05 22.0 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 VBB33545.1 - 0.00011 21.4 0.9 0.00015 20.9 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 VBB33545.1 - 0.00032 19.9 0.1 0.00057 19.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 VBB33545.1 - 0.00036 19.9 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 VBB33545.1 - 0.002 18.7 0.5 0.0051 17.3 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 VBB33545.1 - 0.0027 17.0 0.9 0.0043 16.3 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 VBB33545.1 - 0.0033 16.7 0.2 0.0056 15.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 VBB33545.1 - 0.0069 15.7 0.2 0.014 14.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 VBB33545.1 - 0.015 14.4 0.3 0.021 13.9 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein eIF3_subunit PF08597.10 VBB33546.1 - 9.4e-20 71.5 18.1 1.5e-19 70.9 18.1 1.3 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit Peptidase_C12 PF01088.21 VBB33546.1 - 0.3 10.8 4.0 0.34 10.6 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Str_synth PF03088.16 VBB33547.1 - 1.4e-26 92.5 0.0 3.5e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 VBB33547.1 - 3.9e-09 36.5 0.0 8.4e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 VBB33547.1 - 0.039 14.1 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Sgf11 PF08209.11 VBB33548.1 - 7.3e-18 63.8 0.3 1.1e-17 63.2 0.3 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) PGA2 PF07543.12 VBB33548.1 - 0.0049 16.8 3.5 0.0077 16.2 3.5 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 PBP1_TM PF14812.6 VBB33548.1 - 0.13 12.6 5.9 0.26 11.7 5.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTG PF07742.12 VBB33549.1 - 1.4e-09 37.8 0.0 3.8e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 BTG family GHMP_kinases_C PF08544.13 VBB33549.1 - 1.3e-07 31.9 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Ig_5 PF16681.5 VBB33550.1 - 0.2 12.1 0.1 0.4 11.1 0.1 1.5 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Cor1 PF04803.12 VBB33551.1 - 0.033 14.4 0.5 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Pkinase PF00069.25 VBB33553.1 - 3.1e-12 46.4 0.0 1.6e-09 37.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33553.1 - 3.6e-08 33.0 0.0 7.9e-07 28.6 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB33553.1 - 0.0058 15.5 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB33553.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 VBB33554.1 - 0.16 11.3 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain PFU PF09070.11 VBB33555.1 - 4.8e-28 97.7 0.2 5e-14 52.5 0.1 2.6 1 1 1 2 2 2 2 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 VBB33555.1 - 1e-15 57.8 7.8 0.0012 19.6 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 VBB33555.1 - 1.7e-05 24.8 0.1 0.093 12.8 0.0 3.7 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Mlf1IP PF10248.9 VBB33555.1 - 0.051 13.6 0.2 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein WD40_like PF17005.5 VBB33555.1 - 0.062 12.6 1.3 9.9 5.4 0.0 3.5 1 1 1 3 3 3 0 WD40-like domain SF3A3 PF16837.5 VBB33556.1 - 3.9e-26 91.4 1.2 3.9e-26 91.4 1.2 2.5 4 0 0 4 4 4 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Telomere_Sde2_2 PF13297.6 VBB33556.1 - 8.4e-26 89.4 3.8 1.9e-25 88.2 3.8 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.8 VBB33556.1 - 3.5e-12 46.0 0.2 1.1e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain DUF148 PF02520.17 VBB33556.1 - 0.48 10.6 4.0 4.1 7.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF148 VWA PF00092.28 VBB33557.1 - 3.5e-35 121.8 1.0 5.1e-35 121.3 1.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 VBB33557.1 - 3e-15 56.8 0.4 6.1e-15 55.8 0.4 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 VBB33557.1 - 3.1e-06 27.2 0.1 4.9e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Zona_pellucida PF00100.23 VBB33557.1 - 1.4e-05 25.0 2.3 2.5e-05 24.2 2.3 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C4 PF00105.18 VBB33558.1 - 7.5e-30 103.2 13.0 1.4e-29 102.3 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 VBB33558.1 - 9.6e-16 58.0 0.0 5.5e-15 55.5 0.0 2.0 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LAP1C PF05609.12 VBB33559.1 - 5.6 5.9 16.6 10 5.1 16.6 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 VBB33560.1 - 0.0082 15.5 9.0 0.0082 15.5 9.0 2.9 1 1 1 2 2 2 1 BUD22 RNA_pol_Rpa2_4 PF06883.12 VBB33561.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain Kunitz_BPTI PF00014.23 VBB33562.1 - 7.5e-12 45.3 19.4 5e-06 26.7 6.5 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Helicase_C PF00271.31 VBB33563.1 - 0.0071 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.25 VBB33564.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33564.1 - 3.2e-39 134.8 0.0 6.4e-39 133.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB33564.1 - 1e-05 25.0 0.0 0.0018 17.6 0.0 3.0 2 1 0 2 2 2 1 Kinase-like PB1 PF00564.24 VBB33564.1 - 1.1e-05 25.3 0.3 2e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 VBB33564.1 - 0.0018 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 VBB33564.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 VBB33564.1 - 0.15 11.4 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Filament PF00038.21 VBB33565.1 - 1.7e-68 231.5 50.4 3.4e-67 227.2 50.4 2.1 1 1 0 1 1 1 1 Intermediate filament protein APG6_N PF17675.1 VBB33565.1 - 0.00019 21.9 47.2 0.34 11.4 5.0 5.3 2 1 2 4 4 4 2 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 VBB33565.1 - 0.00096 19.2 8.7 0.00096 19.2 8.7 5.0 1 1 4 5 5 5 4 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.19 VBB33565.1 - 0.0049 14.8 43.6 1.3 6.8 43.6 2.9 1 1 0 1 1 1 1 Myosin tail Herpes_UL6 PF01763.16 VBB33565.1 - 0.019 13.5 21.5 0.15 10.6 0.5 3.2 1 1 1 3 3 3 0 Herpesvirus UL6 like GAS PF13851.6 VBB33565.1 - 0.023 14.0 46.7 0.014 14.8 6.7 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 VBB33565.1 - 0.034 13.8 42.2 0.37 10.4 19.1 3.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SOGA PF11365.8 VBB33565.1 - 0.053 14.7 32.3 0.43 11.7 2.6 6.2 2 1 3 5 5 5 0 Protein SOGA Metal_resist PF13801.6 VBB33565.1 - 0.059 13.6 0.7 0.059 13.6 0.7 3.5 3 0 0 3 3 3 0 Heavy-metal resistance Spc7 PF08317.11 VBB33565.1 - 0.059 12.2 39.0 0.082 11.8 12.1 3.4 1 1 2 4 4 4 0 Spc7 kinetochore protein KASH_CCD PF14662.6 VBB33565.1 - 0.068 13.0 42.1 0.42 10.4 1.1 3.7 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 VBB33565.1 - 0.099 12.7 47.1 0.73 9.9 16.9 4.2 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 VBB33565.1 - 0.5 11.0 34.0 1.4 9.6 2.1 5.4 1 1 3 5 5 5 0 Initiation control protein YabA Fez1 PF06818.15 VBB33565.1 - 0.6 10.5 40.8 2.1 8.8 5.3 3.5 1 1 1 3 3 3 0 Fez1 DHR10 PF18595.1 VBB33565.1 - 0.73 9.9 47.2 0.032 14.3 7.9 5.0 3 2 0 4 4 4 0 Designed helical repeat protein 10 domain ADIP PF11559.8 VBB33565.1 - 0.95 9.5 36.1 0.76 9.9 5.3 4.9 2 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 VBB33565.1 - 1.2 9.2 41.5 3.9 7.6 14.5 3.4 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 VBB33565.1 - 1.3 9.5 20.0 0.49 10.8 1.5 5.6 5 2 1 6 6 5 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 VBB33565.1 - 1.4 8.3 45.0 0.78 9.1 3.6 3.5 1 1 1 3 3 3 0 Golgin subfamily A member 5 CCDC144C PF14915.6 VBB33565.1 - 2.4 7.2 40.4 1.2 8.2 17.5 3.2 1 1 2 3 3 3 0 CCDC144C protein coiled-coil region SNCAIP_SNCA_bd PF16700.5 VBB33565.1 - 4.2 7.2 9.5 0.16 11.7 0.5 3.3 4 0 0 4 4 3 0 Synphilin-1 alpha-Synuclein-binding domain Tweety PF04906.13 VBB33565.1 - 5.4 5.6 8.8 0.44 9.2 1.0 2.6 3 0 0 3 3 3 0 Tweety WD40 PF00400.32 VBB33566.1 - 2.3e-25 88.4 4.2 7.9e-08 32.8 0.2 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 VBB33566.1 - 0.00082 18.1 2.1 0.058 12.0 0.1 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1416 PF07210.12 VBB33566.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) STAT_bind PF02864.15 VBB33567.1 - 1.1e-37 129.5 0.1 2.9e-37 128.2 0.1 1.8 1 0 0 1 1 1 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 VBB33567.1 - 4.4e-20 72.3 11.5 7e-20 71.6 11.5 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain SH2 PF00017.24 VBB33567.1 - 6.7e-07 29.3 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Tup_N PF08581.10 VBB33567.1 - 0.0022 18.2 4.0 0.011 16.0 0.3 3.0 2 1 0 3 3 3 1 Tup N-terminal EF-hand_12 PF17901.1 VBB33567.1 - 0.031 14.7 2.9 0.23 11.9 2.9 2.4 1 1 0 1 1 1 0 EF-hand fold domain Virulence_fact PF13769.6 VBB33567.1 - 0.04 14.2 0.4 2.5 8.4 0.0 2.8 3 0 0 3 3 3 0 Virulence factor EF-hand_7 PF13499.6 VBB33568.1 - 8.2e-12 45.4 0.0 2.4e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB33568.1 - 9e-07 28.3 0.3 0.012 15.5 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 VBB33568.1 - 4.8e-06 26.3 0.0 0.21 11.4 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 VBB33568.1 - 1.1e-05 24.6 0.0 0.046 13.3 0.0 3.0 3 0 0 3 3 3 2 EF hand LPD11 PF18824.1 VBB33568.1 - 0.041 14.0 0.6 3.9 7.6 0.2 2.8 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 OmpH PF03938.14 VBB33569.1 - 0.093 13.1 6.1 1.9 8.9 6.3 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SMYLE_N PF18615.1 VBB33569.1 - 0.15 11.6 3.0 0.24 10.9 3.0 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain VSG_B PF13206.6 VBB33569.1 - 4.9 6.3 5.7 1.5 8.0 2.8 1.5 2 0 0 2 2 2 0 Trypanosomal VSG domain SCIMP PF15050.6 VBB33570.1 - 0.012 16.0 0.5 4.8 7.7 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein DM PF00751.18 VBB33571.1 - 5.9e-06 26.1 7.5 1e-05 25.3 7.5 1.4 1 0 0 1 1 1 1 DM DNA binding domain FpoO PF10621.9 VBB33571.1 - 0.065 13.5 0.0 0.076 13.3 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO AAA PF00004.29 VBB33572.1 - 1.1e-16 61.4 0.0 2.7e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 VBB33572.1 - 1.4e-15 57.5 0.1 5.5e-15 55.6 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 VBB33572.1 - 3.5e-11 43.1 4.3 1.8e-10 40.8 0.1 2.6 2 1 0 2 2 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 VBB33572.1 - 0.0001 22.1 0.0 0.00027 20.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 VBB33572.1 - 0.00013 22.0 0.2 0.0017 18.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 VBB33572.1 - 0.00015 21.8 0.0 0.00015 21.8 0.0 2.2 2 1 0 2 2 1 1 Rad17 P-loop domain AAA_11 PF13086.6 VBB33572.1 - 0.0002 21.3 8.2 0.0092 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 VBB33572.1 - 0.0017 18.8 0.9 0.027 14.8 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 VBB33572.1 - 0.0029 17.9 0.0 0.0029 17.9 0.0 2.6 3 0 0 3 3 2 1 AAA C-terminal domain AAA_7 PF12775.7 VBB33572.1 - 0.0045 16.5 0.0 0.024 14.2 0.0 2.1 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 VBB33572.1 - 0.0062 16.8 1.8 0.93 9.8 0.4 3.3 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 VBB33572.1 - 0.0071 15.8 0.1 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein DDHD PF02862.17 VBB33572.1 - 0.0071 16.5 3.8 0.011 15.9 3.8 1.3 1 0 0 1 1 1 1 DDHD domain AAA_24 PF13479.6 VBB33572.1 - 0.0086 15.8 1.9 0.01 15.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 VBB33572.1 - 0.03 13.5 0.0 0.075 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RecR PF02132.15 VBB33572.1 - 0.068 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 RecR protein Mg_chelatase PF01078.21 VBB33572.1 - 0.16 11.4 2.5 0.81 9.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Hid1 PF12722.7 VBB33572.1 - 0.18 9.9 11.0 0.27 9.3 11.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 VBB33572.1 - 0.2 10.4 6.1 0.34 9.6 6.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Miga PF10265.9 VBB33572.1 - 0.41 9.6 6.2 0.59 9.0 6.2 1.2 1 0 0 1 1 1 0 Mitoguardin PAT1 PF09770.9 VBB33572.1 - 0.45 8.7 18.5 0.63 8.2 18.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 VBB33572.1 - 1.1 9.1 10.0 1.7 8.4 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Auxin_canalis PF05703.11 VBB33572.1 - 1.2 9.0 6.5 2.1 8.2 6.5 1.5 1 0 0 1 1 1 0 Auxin canalisation TFIIA PF03153.13 VBB33572.1 - 1.5 8.7 31.3 2.3 8.1 31.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 VBB33572.1 - 4 6.1 15.2 5.9 5.5 15.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 VBB33572.1 - 7.2 5.9 11.8 14 5.0 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Med19 PF10278.9 VBB33573.1 - 7e-44 149.9 2.7 9.2e-44 149.5 2.7 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 GEN1_C PF18380.1 VBB33573.1 - 0.74 10.7 5.8 1.5 9.7 5.8 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Gcd10p PF04189.13 VBB33574.1 - 9.7e-28 97.1 0.1 1.1e-27 96.9 0.1 1.1 1 0 0 1 1 1 1 Gcd10p family RBD-FIP PF09457.10 VBB33576.1 - 3.9e-11 42.7 1.2 3.9e-11 42.7 1.2 3.1 3 0 0 3 3 3 1 FIP domain MbeD_MobD PF04899.12 VBB33576.1 - 0.27 11.4 12.4 3.6 7.8 0.2 4.6 3 1 2 5 5 5 0 MbeD/MobD like ATG16 PF08614.11 VBB33576.1 - 0.55 10.4 37.9 2.2 8.5 10.2 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) YabA PF06156.13 VBB33576.1 - 1.3 9.7 35.1 0.16 12.6 4.4 4.7 1 1 2 3 3 3 0 Initiation control protein YabA Leu_zip PF15294.6 VBB33576.1 - 1.3 8.4 34.6 0.27 10.7 10.6 2.4 1 1 1 2 2 2 0 Leucine zipper TPR_MLP1_2 PF07926.12 VBB33576.1 - 6.7 6.8 39.9 16 5.6 9.1 3.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4704 PF15787.5 VBB33578.1 - 0.045 13.0 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Ribosomal_S13_N PF08069.12 VBB33579.1 - 2.4e-31 107.5 0.2 5.6e-31 106.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 VBB33579.1 - 5.7e-15 55.3 2.2 1e-14 54.5 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 YflT PF11181.8 VBB33579.1 - 0.005 17.3 0.0 0.0082 16.6 0.0 1.4 1 0 0 1 1 1 1 Heat induced stress protein YflT PAX PF00292.18 VBB33579.1 - 0.01 15.8 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 'Paired box' domain BTRD1 PF17660.1 VBB33579.1 - 0.021 14.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 LexA_DNA_bind PF01726.16 VBB33579.1 - 0.027 14.2 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 LexA DNA binding domain DUF3140 PF11338.8 VBB33579.1 - 0.071 13.6 0.3 0.11 13.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) ANAPC4_WD40 PF12894.7 VBB33580.1 - 3.5e-11 43.3 0.1 6.5e-05 23.2 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 VBB33580.1 - 4.3e-05 21.7 0.1 6.7e-05 21.1 0.1 1.2 1 0 0 1 1 1 1 IKI3 family WD40 PF00400.32 VBB33580.1 - 0.00032 21.4 0.0 1 10.3 0.0 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 VBB33580.1 - 0.0026 16.9 0.0 0.0028 16.8 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 VBB33580.1 - 0.015 15.2 0.0 2.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 VBB33581.1 - 5.1e-16 58.8 7.3 1.6e-06 28.8 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB33581.1 - 2.7e-10 40.4 0.0 0.064 13.6 0.0 5.9 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 VBB33581.1 - 6.3e-06 25.5 7.8 0.0044 16.1 0.2 5.3 4 1 2 6 6 6 2 Coatomer WD associated region PHTB1_N PF14727.6 VBB33581.1 - 0.00043 19.8 0.1 0.0048 16.3 0.1 2.2 1 1 1 2 2 2 1 PTHB1 N-terminus eIF2A PF08662.11 VBB33581.1 - 0.001 19.0 0.1 0.022 14.6 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 VBB33581.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split YhdB PF14148.6 VBB33581.1 - 0.5 10.5 3.5 6 7.1 3.5 2.9 1 1 0 1 1 1 0 YhdB-like protein Laminin_N PF00055.17 VBB33582.1 - 1.1e-71 241.1 0.0 1.1e-71 241.1 0.0 2.9 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 VBB33582.1 - 8.3e-30 103.4 0.0 1.4e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_EGF PF00053.24 VBB33582.1 - 1.7e-21 76.1 109.8 3.3e-07 30.3 12.9 7.4 7 0 0 7 7 7 5 Laminin EGF domain F5_F8_type_C PF00754.25 VBB33582.1 - 0.00024 21.2 0.0 0.0061 16.7 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain Retrotran_gag_3 PF14244.6 VBB33582.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HLH PF00010.26 VBB33583.1 - 1.5e-13 50.5 0.4 1.7e-13 50.3 0.4 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ctr PF04145.15 VBB33584.1 - 3.8e-28 99.0 5.9 4.7e-28 98.7 5.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SH PF01445.17 VBB33584.1 - 3.1 7.8 7.3 0.25 11.4 1.6 2.0 2 0 0 2 2 2 0 Viral small hydrophobic protein Septin PF00735.18 VBB33586.1 - 5.5e-37 127.6 0.1 7.6e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 VBB33586.1 - 0.00034 20.7 0.2 0.00085 19.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 VBB33586.1 - 0.0025 18.1 0.1 0.005 17.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 VBB33586.1 - 0.0065 16.7 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 VBB33586.1 - 0.0093 15.5 1.6 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 VBB33586.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 VBB33586.1 - 0.015 15.2 0.4 0.095 12.6 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding Pox_A32 PF04665.12 VBB33586.1 - 0.036 13.5 0.1 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein AMPKBI PF04739.15 VBB33586.1 - 0.054 13.8 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain PduV-EutP PF10662.9 VBB33586.1 - 0.056 13.2 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 VBB33586.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras family NB-ARC PF00931.22 VBB33586.1 - 0.086 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 VBB33586.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Alpha-amylase_C PF02806.18 VBB33587.1 - 4.5e-22 78.3 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain tRNA-synt_1b PF00579.25 VBB33588.1 - 2.2e-88 296.4 0.0 3.5e-60 203.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Peptidase_M13 PF01431.21 VBB33589.1 - 1.5e-60 204.3 0.1 1.7e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 FGE-sulfatase PF03781.16 VBB33589.1 - 0.061 12.9 0.1 0.086 12.4 0.1 1.2 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 Carb_anhydrase PF00194.21 VBB33590.1 - 5.8e-35 121.0 0.0 6.7e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CAP PF00188.26 VBB33591.1 - 4.7e-25 88.9 1.7 5.8e-25 88.6 1.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Collagen PF01391.18 VBB33592.1 - 8.6e-11 41.4 28.2 1.1e-10 41.1 28.2 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) WH1 PF00568.23 VBB33593.1 - 0.0044 16.9 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Pneumovirus_M2 PF06436.11 VBB33593.1 - 0.017 14.6 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) MH2 PF03166.14 VBB33595.1 - 2.3e-61 207.3 0.2 3.1e-61 206.9 0.2 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 VBB33595.1 - 1.8e-37 127.7 0.5 3.6e-37 126.7 0.5 1.5 1 0 0 1 1 1 1 MH1 domain SapB_1 PF05184.15 VBB33596.1 - 0.041 13.9 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Exog_C PF18026.1 VBB33596.1 - 0.079 13.0 0.8 0.75 9.9 0.1 2.5 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain DUF3837 PF12939.7 VBB33596.1 - 0.22 11.9 3.0 6.5 7.2 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3837) BRAP2 PF07576.12 VBB33596.1 - 0.28 11.4 2.2 0.4 10.9 0.4 2.1 2 1 0 2 2 2 0 BRCA1-associated protein 2 Dehydrin PF00257.19 VBB33596.1 - 1.9 9.0 6.5 9.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Dehydrin TFIIA PF03153.13 VBB33596.1 - 5.4 6.9 23.0 7.9 6.4 23.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TetR_C_8 PF14278.6 VBB33596.1 - 6.5 6.9 7.7 28 4.9 1.9 3.2 1 1 2 3 3 3 0 Transcriptional regulator C-terminal region Ras PF00071.22 VBB33597.1 - 2.6e-08 33.6 0.0 5.9e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Ras family DnaG_DnaB_bind PF08278.11 VBB33598.1 - 0.016 15.8 0.0 0.046 14.3 0.0 1.8 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Symplekin_C PF12295.8 VBB33598.1 - 0.039 14.0 2.3 9.1 6.3 0.3 3.0 2 1 2 4 4 4 0 Symplekin tight junction protein C terminal NDUF_B4 PF07225.12 VBB33599.1 - 9.8e-35 119.2 0.2 1.3e-34 118.8 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) TPR_14 PF13428.6 VBB33600.1 - 0.00055 20.5 0.1 0.44 11.5 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33600.1 - 0.0011 19.4 0.4 0.51 10.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 VBB33600.1 - 0.0057 16.3 1.5 0.015 15.0 0.7 2.0 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 VBB33600.1 - 0.017 15.3 0.4 0.067 13.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 VBB33600.1 - 0.1 12.7 0.2 0.81 9.9 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33600.1 - 0.14 12.3 3.6 0.81 10.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33600.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 VBB33603.1 - 9.2e-26 87.4 6.8 9.2e-07 28.0 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB33603.1 - 4.8e-25 87.8 4.3 3.1e-12 46.8 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB33603.1 - 2.9e-23 79.8 0.8 4.4e-05 23.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 VBB33603.1 - 2.3e-19 67.9 5.9 2e-05 23.9 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 VBB33603.1 - 1.7e-17 63.0 4.9 2.3e-05 24.1 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 VBB33603.1 - 1.2e-07 31.9 0.6 0.0019 18.5 0.0 3.0 1 1 2 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.9 VBB33603.1 - 1.9e-06 28.2 0.5 0.00098 19.4 0.2 2.4 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 VBB33603.1 - 1.6e-05 25.0 0.3 0.3 11.3 0.3 3.4 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_4 PF12763.7 VBB33603.1 - 5.4e-05 23.1 2.5 0.034 14.1 0.1 2.8 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 VBB33603.1 - 0.012 15.5 0.3 0.27 11.1 0.0 2.7 2 1 1 3 3 3 0 EF hand CSTF_C PF14304.6 VBB33603.1 - 0.37 10.4 1.3 25 4.5 0.0 2.6 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal F-box PF00646.33 VBB33604.1 - 5.3e-09 35.7 1.6 8e-09 35.2 1.6 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 VBB33604.1 - 2.6e-08 33.6 0.6 3.8e-08 33.1 0.6 1.2 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 VBB33604.1 - 0.067 13.2 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 F-box-like domain ANF_receptor PF01094.28 VBB33605.1 - 5.7e-05 22.4 0.0 8.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DUF782 PF05614.11 VBB33605.1 - 0.077 13.4 0.0 0.89 10.0 0.0 2.4 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) DUF3149 PF11346.8 VBB33605.1 - 4.7 6.9 7.0 0.21 11.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DOMON PF03351.17 VBB33606.1 - 7e-14 52.1 0.0 9.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 DOMON domain RabGAP-TBC PF00566.18 VBB33607.1 - 2.9e-50 170.9 0.1 4.7e-50 170.2 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 VBB33607.1 - 1.1e-23 83.7 0.8 2.6e-23 82.5 0.8 1.7 1 0 0 1 1 1 1 RUN domain SH3_2 PF07653.17 VBB33607.1 - 6e-11 41.9 0.1 1.2e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB33607.1 - 8e-11 41.4 0.0 1.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB33607.1 - 1.2e-09 37.8 0.2 2.9e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain tRNA_Me_trans PF03054.16 VBB33608.1 - 0.1 11.4 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Sugar_tr PF00083.24 VBB33609.1 - 2.3e-21 76.2 5.0 2.8e-21 75.9 5.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB33609.1 - 1.5e-20 73.4 8.8 1.9e-20 73.1 8.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Galactosyl_T PF01762.21 VBB33609.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Galactosyltransferase AMP-binding PF00501.28 VBB33610.1 - 2.7e-21 75.7 0.0 4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB33610.1 - 2.9e-06 28.2 0.0 9.6e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glycos_transf_2 PF00535.26 VBB33612.1 - 1.6e-31 109.4 0.0 2.8e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 VBB33612.1 - 2.7e-14 53.5 0.3 2.1e-12 47.4 0.3 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 VBB33612.1 - 1.6e-07 30.9 0.1 3.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 VBB33612.1 - 2.1e-06 27.8 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 VBB33612.1 - 0.0011 18.6 0.0 0.005 16.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CDtoxinA PF03498.14 VBB33612.1 - 0.13 11.9 0.1 0.53 9.9 0.0 1.9 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain Prolamin_like PF05617.11 VBB33614.1 - 0.29 11.3 4.9 0.69 10.1 2.9 2.1 1 1 0 2 2 2 0 Prolamin-like MADF_DNA_bdg PF10545.9 VBB33615.1 - 4.2e-10 39.8 1.4 5.8e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 VBB33615.1 - 0.0077 16.6 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Inhibitor_I78 PF11720.8 VBB33616.1 - 0.1 12.7 0.2 24 5.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase inhibitor I78 family 2OG-FeII_Oxy_2 PF13532.6 VBB33617.1 - 5.5e-19 69.1 0.0 1e-18 68.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 VBB33617.1 - 2.3e-14 53.8 0.0 5.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB33617.1 - 2.8e-12 47.2 0.0 6.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB33617.1 - 1.8e-05 24.6 0.4 0.00012 21.9 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB33617.1 - 5.4e-05 23.9 0.1 0.00024 21.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 VBB33617.1 - 0.00018 20.9 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 VBB33617.1 - 0.0012 18.7 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 VBB33617.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 VBB33617.1 - 0.004 17.0 0.3 0.012 15.4 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tir_receptor_M PF03549.14 VBB33617.1 - 0.16 12.3 0.0 0.42 11.0 0.0 1.7 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain zf-C3HC4_3 PF13920.6 VBB33618.1 - 0.0011 18.8 13.2 0.0011 18.8 13.2 4.5 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) HscB_4_cys PF18256.1 VBB33618.1 - 2.6 7.9 7.0 14 5.6 1.4 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-C2H2_11 PF16622.5 VBB33618.1 - 7.5 6.4 7.5 33 4.3 0.7 3.8 3 1 0 3 3 3 0 zinc-finger C2H2-type GST_N_3 PF13417.6 VBB33619.1 - 5.1e-10 39.6 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 VBB33619.1 - 4e-08 33.5 0.5 1.5e-07 31.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 VBB33619.1 - 5.5e-06 26.3 0.1 9.2e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 VBB33619.1 - 4.8e-05 23.6 0.1 0.00028 21.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 VBB33619.1 - 0.00026 21.2 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 VBB33619.1 - 0.0035 17.5 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 VBB33619.1 - 0.027 14.3 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DnaJ_C PF01556.18 VBB33620.1 - 1.5e-27 96.5 0.0 2.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 VBB33620.1 - 1.6e-25 89.0 5.5 2.8e-25 88.2 5.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 VBB33620.1 - 5.4e-08 33.1 13.0 1.3e-07 31.9 13.0 1.7 1 0 0 1 1 1 1 DnaJ central domain GST_C_2 PF13410.6 VBB33620.1 - 2.7e-05 24.1 0.1 5.8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 VBB33620.1 - 0.0015 18.7 0.2 0.0035 17.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 VBB33620.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 VBB33620.1 - 0.067 13.0 0.1 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 VBB33620.1 - 0.19 12.1 0.2 0.8 10.2 0.1 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF5351 PF17302.2 VBB33620.1 - 0.49 10.6 21.9 0.032 14.4 11.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 VBB33620.1 - 1.3 9.1 12.4 3.2 7.8 1.3 3.5 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Mannitol_dh PF01232.23 VBB33621.1 - 0.094 12.9 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Abhydrolase_2 PF02230.16 VBB33622.1 - 3.9e-75 252.4 0.0 4.4e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 VBB33622.1 - 2.4e-06 27.0 0.5 0.0016 17.8 0.1 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 VBB33622.1 - 5.4e-06 26.1 0.0 8.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 VBB33622.1 - 9.7e-06 26.3 0.0 1.1e-05 26.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 VBB33622.1 - 0.00017 21.3 1.7 0.0015 18.2 1.7 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 VBB33622.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 VBB33622.1 - 0.044 13.6 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 VBB33622.1 - 0.047 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2048 PF09752.9 VBB33622.1 - 0.15 11.1 0.2 1.3 8.0 0.1 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 EMP70 PF02990.16 VBB33623.1 - 2e-160 534.9 0.0 2.3e-160 534.7 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 CopD PF05425.13 VBB33623.1 - 0.024 15.0 4.8 0.034 14.6 3.9 1.7 1 1 0 1 1 1 0 Copper resistance protein D DUF3139 PF11337.8 VBB33623.1 - 0.13 12.9 0.0 0.6 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF1523 PF07509.11 VBB33623.1 - 0.17 11.2 1.0 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1523) UDPGT PF00201.18 VBB33624.1 - 6e-34 117.7 0.1 8.1e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Not3 PF04065.15 VBB33624.1 - 5.3e-12 45.7 3.6 9.4e-12 44.9 3.6 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Glyco_tran_28_C PF04101.16 VBB33624.1 - 1.4e-05 25.2 0.1 3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Copine PF07002.16 VBB33626.1 - 1.3e-69 234.0 0.0 1.6e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 VBB33626.1 - 7.6e-07 29.4 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 VBB33626.1 - 0.0046 17.1 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus MaoC_dehydratas PF01575.19 VBB33627.1 - 0.19 11.3 2.2 0.28 10.8 2.2 1.2 1 0 0 1 1 1 0 MaoC like domain KH_1 PF00013.29 VBB33628.1 - 1.4e-28 98.5 3.9 2.5e-19 68.9 0.7 2.7 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 VBB33628.1 - 1.7e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KH domain RskA PF10099.9 VBB33628.1 - 0.0031 17.8 1.0 0.0058 16.9 1.0 1.5 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Med3 PF11593.8 VBB33628.1 - 0.0052 16.0 6.4 0.0065 15.7 6.4 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 VBB33628.1 - 0.0098 15.9 5.2 0.025 14.7 5.2 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 VBB33628.1 - 0.04 13.9 2.2 0.043 13.8 2.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 VBB33628.1 - 0.056 13.0 4.7 0.076 12.6 4.7 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 VBB33628.1 - 1.3 7.7 11.8 2.6 6.8 11.8 1.4 1 0 0 1 1 1 0 Androgen receptor SAC3_GANP PF03399.16 VBB33629.1 - 7e-15 55.2 0.8 8.3e-15 54.9 0.8 1.1 1 0 0 1 1 1 1 SAC3/GANP family CLU_N PF15044.6 VBB33629.1 - 0.09 13.1 0.4 0.21 12.0 0.1 1.7 1 1 1 2 2 2 0 Mitochondrial function, CLU-N-term MIF PF01187.18 VBB33630.1 - 7.5e-51 171.2 0.0 8.3e-51 171.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF3268 PF11672.8 VBB33630.1 - 0.05 13.9 0.0 0.24 11.8 0.0 1.9 2 1 1 3 3 3 0 zinc-finger-containing domain SRP54_N PF02881.19 VBB33631.1 - 0.089 13.0 0.2 0.18 12.1 0.2 1.5 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain CBM_14 PF01607.24 VBB33632.1 - 1.7e-23 82.5 54.5 1.1e-07 31.9 7.9 6.7 4 2 2 6 6 6 5 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 VBB33632.1 - 0.0014 18.6 19.0 0.072 13.1 0.0 5.2 4 1 0 4 4 4 3 Carbohydrate binding domain (family 19) WD40 PF00400.32 VBB33633.1 - 1.7e-21 76.1 5.0 0.0037 18.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 VBB33633.1 - 1.1e-06 27.7 3.1 0.044 12.4 0.5 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 VBB33633.1 - 0.013 14.8 0.0 0.065 12.6 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain eIF2A PF08662.11 VBB33633.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ricin_B_lectin PF00652.22 VBB33633.1 - 0.035 14.3 2.8 0.12 12.6 1.4 2.5 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain zf-H2C2_2 PF13465.6 VBB33635.1 - 1.3e-12 47.5 17.6 4.9e-06 26.7 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 VBB33635.1 - 8.8e-12 44.7 14.9 1.2e-06 28.4 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB33635.1 - 2.6e-11 43.3 26.6 6.8e-05 23.1 1.2 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB33635.1 - 2.1e-09 37.4 15.0 0.00038 21.1 0.6 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 VBB33635.1 - 3.8e-08 33.4 8.6 0.0024 18.2 0.0 4.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB33635.1 - 8.7e-06 25.9 14.2 0.0078 16.5 0.1 4.3 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 VBB33635.1 - 0.00098 19.8 0.2 0.00098 19.8 0.2 2.9 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 VBB33635.1 - 0.0014 18.7 9.4 0.17 12.0 0.4 2.9 2 1 0 2 2 2 2 Zinc ribbon domain C1_4 PF07975.12 VBB33635.1 - 0.017 15.3 5.7 0.16 12.2 3.0 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain BolA PF01722.18 VBB33635.1 - 0.037 14.3 1.4 0.95 9.8 0.6 2.8 1 1 2 3 3 3 0 BolA-like protein zf_UBZ PF18439.1 VBB33635.1 - 0.043 13.4 7.2 1.8 8.2 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 VBB33635.1 - 0.047 13.8 6.0 8.7 6.6 0.7 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 VBB33635.1 - 0.19 12.0 8.0 1.2 9.5 0.7 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zinc-ribbons_6 PF07191.12 VBB33635.1 - 0.25 11.3 9.4 11 6.1 9.4 2.9 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.19 VBB33635.1 - 0.27 11.3 7.4 0.82 9.7 1.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 VBB33635.1 - 0.29 11.5 16.1 0.15 12.4 2.4 3.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 VBB33635.1 - 0.39 10.5 7.3 3.5 7.5 0.3 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type XPA_N PF01286.18 VBB33635.1 - 0.55 10.3 10.2 10 6.3 1.1 3.7 3 0 0 3 3 3 0 XPA protein N-terminal zf_C2H2_ZHX PF18387.1 VBB33635.1 - 0.77 9.5 10.5 1.4 8.6 0.1 3.4 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 VBB33635.1 - 3.6 7.9 13.1 7.3 6.9 4.8 3.4 3 1 1 4 4 4 0 LIM domain GATA PF00320.27 VBB33635.1 - 3.8 7.2 12.6 35 4.1 0.3 4.2 3 1 1 4 4 4 0 GATA zinc finger C1_2 PF03107.16 VBB33635.1 - 5.6 7.4 16.7 4.1 7.8 6.8 3.5 2 1 1 3 3 2 0 C1 domain TFIIS_C PF01096.18 VBB33635.1 - 9.7 6.1 12.2 11 5.9 0.1 3.5 4 0 0 4 4 3 0 Transcription factor S-II (TFIIS) Acetyltransf_1 PF00583.25 VBB33637.1 - 5.3e-09 36.3 0.0 8.3e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 VBB33637.1 - 1.5e-05 25.2 0.3 3.2e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 VBB33637.1 - 8.6e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 VBB33637.1 - 0.00015 22.1 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 VBB33637.1 - 0.0044 17.1 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Glyco_hydro_4 PF02056.16 VBB33637.1 - 0.025 14.2 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase LuxT_C PF18285.1 VBB33637.1 - 0.055 14.0 0.2 0.13 12.9 0.2 1.6 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain Acetyltransf_3 PF13302.7 VBB33637.1 - 0.073 13.8 0.3 0.13 12.9 0.3 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain T3RM_EcoP15I_C PF18273.1 VBB33637.1 - 0.12 12.7 0.8 8.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain FR47 PF08445.10 VBB33637.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Ras PF00071.22 VBB33639.1 - 3.9e-42 143.6 0.0 5e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB33639.1 - 3.9e-18 65.8 0.0 7.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB33639.1 - 0.0041 16.6 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 VBB33639.1 - 0.022 15.1 0.0 0.3 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 VBB33639.1 - 0.065 13.3 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 VBB33639.1 - 0.075 12.4 0.0 0.47 9.8 0.0 2.2 3 0 0 3 3 3 0 Bacterial TniB protein FeoB_N PF02421.18 VBB33639.1 - 0.13 11.8 0.0 8.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B WD40 PF00400.32 VBB33640.1 - 2.9e-09 37.4 3.7 0.00013 22.7 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB33640.1 - 0.00068 19.9 0.0 2.2 8.6 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4221 PF13970.6 VBB33640.1 - 0.1 12.2 0.0 0.91 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) Phage_capsid PF05065.13 VBB33641.1 - 0.039 13.2 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Phage capsid family Dynein_light PF01221.18 VBB33641.1 - 0.048 14.0 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light chain type 1 Acatn PF13000.7 VBB33642.1 - 1.6e-41 142.4 13.2 8.7e-27 93.8 5.4 3.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Pex24p PF06398.11 VBB33642.1 - 0.08 11.9 0.0 0.08 11.9 0.0 2.4 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Cadherin_C_2 PF16492.5 VBB33642.1 - 0.087 13.6 0.3 0.49 11.2 0.1 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4519 PF15012.6 VBB33642.1 - 0.13 12.5 0.4 0.43 10.8 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) FixQ PF05545.11 VBB33642.1 - 1.7 8.7 7.0 4.5 7.3 0.0 3.7 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ zf-CDGSH PF09360.10 VBB33643.1 - 1.9e-18 66.4 3.0 1.1e-08 35.1 0.2 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type dTDP_sugar_isom PF00908.17 VBB33646.1 - 7.9e-60 201.4 0.0 1e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase zf-RanBP PF00641.18 VBB33647.1 - 3.7e-08 32.5 2.1 8.9e-08 31.3 2.1 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others YAF2_RYBP PF17219.3 VBB33647.1 - 1.2e-06 28.0 0.0 3.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-CCCH PF00642.24 VBB33648.1 - 1e-08 34.9 6.3 1.6e-07 31.1 4.8 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB33648.1 - 1.2e-05 25.2 2.9 1.2e-05 25.2 2.9 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 VBB33648.1 - 0.0062 16.3 3.8 0.0062 16.3 3.8 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 VBB33648.1 - 0.086 13.5 1.2 0.18 12.5 1.2 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 VBB33648.1 - 1.8 9.1 6.4 0.61 10.7 1.4 2.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CD52 PF15116.6 VBB33648.1 - 5.8 7.0 8.8 1.3 9.1 4.5 2.0 2 0 0 2 2 2 0 CAMPATH-1 antigen ALIX_LYPXL_bnd PF13949.6 VBB33649.1 - 0.008 15.5 2.7 0.012 15.0 1.1 2.2 1 1 2 3 3 3 2 ALIX V-shaped domain binding to HIV CENP-F_leu_zip PF10473.9 VBB33649.1 - 0.021 14.8 1.6 0.021 14.8 1.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 VBB33649.1 - 0.055 13.9 2.0 0.19 12.2 0.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin PI3K_P85_iSH2 PF16454.5 VBB33649.1 - 0.6 9.7 6.6 0.057 13.0 1.6 1.8 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tmp39 PF10271.9 VBB33651.1 - 6.2e-84 282.5 17.9 1.2e-34 120.1 11.0 3.0 2 1 1 3 3 3 3 Putative transmembrane protein SSP160 PF06933.11 VBB33651.1 - 1.1 7.4 8.1 1.6 6.8 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 POT1PC PF16686.5 VBB33652.1 - 5.6e-24 84.8 0.0 3.7e-23 82.1 0.0 2.1 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 VBB33652.1 - 5e-14 52.3 0.2 2.6e-12 46.8 0.1 2.7 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 VBB33652.1 - 0.12 12.1 0.3 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 PRKCSH PF07915.13 VBB33653.1 - 1.6e-28 99.5 11.4 4.2e-14 53.3 3.2 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 VBB33653.1 - 5.1e-09 36.0 0.0 0.00092 18.9 0.0 2.7 2 2 0 2 2 2 2 Glucosidase II beta subunit-like protein CENP-Q PF13094.6 VBB33653.1 - 0.023 14.9 0.1 0.043 14.0 0.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.20 VBB33654.1 - 1.1e-18 67.2 5.9 1.6e-18 66.6 5.9 1.3 1 0 0 1 1 1 1 Prefoldin subunit Vps39_1 PF10366.9 VBB33654.1 - 0.039 14.2 2.8 0.36 11.1 0.4 2.4 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 APG6_N PF17675.1 VBB33654.1 - 2.6 8.6 13.3 1.3 9.6 5.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Vinculin PF01044.19 VBB33656.1 - 1e-210 702.6 40.6 8.6e-159 530.7 24.6 2.8 1 1 1 2 2 2 2 Vinculin family U62_UL91 PF17442.2 VBB33656.1 - 0.0039 17.2 0.1 0.16 12.0 0.0 3.2 2 0 0 2 2 2 1 Functional domain of U62 and UL91 proteins ODR4-like PF14778.6 VBB33656.1 - 0.0069 15.4 1.1 0.016 14.1 0.1 2.1 2 0 0 2 2 2 1 Olfactory receptor 4-like DUF4363 PF14276.6 VBB33656.1 - 0.047 13.8 2.6 2.7 8.1 0.0 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) DUF2120 PF09893.9 VBB33656.1 - 0.55 10.3 9.2 2.8 8.0 1.6 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2120) DUF2115 PF09888.9 VBB33656.1 - 5.4 7.5 9.1 3 8.4 0.1 3.6 4 1 1 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2115) Pkinase PF00069.25 VBB33657.1 - 6.2e-20 71.7 0.0 6.2e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33657.1 - 6.2e-14 51.9 0.3 1.8e-13 50.4 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB33657.1 - 4.4e-06 25.7 4.5 1.7e-05 23.8 4.5 2.2 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 VBB33657.1 - 0.023 14.3 9.2 0.13 11.8 0.0 3.2 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DDHD PF02862.17 VBB33657.1 - 0.027 14.6 0.4 0.034 14.3 0.4 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 VBB33657.1 - 0.13 11.0 2.9 0.16 10.7 2.9 1.1 1 0 0 1 1 1 0 Presenilin RAB3GAP2_N PF14655.6 VBB33657.1 - 0.24 10.6 6.6 0.36 10.0 6.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.8 VBB33657.1 - 0.3 10.0 15.3 0.41 9.5 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Band_3_cyto PF07565.13 VBB33657.1 - 0.3 10.8 4.1 0.51 10.1 4.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.8 VBB33657.1 - 1.4 8.5 26.4 2.8 7.5 26.4 1.5 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 VBB33657.1 - 1.8 7.7 15.1 2.4 7.3 15.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med15 PF09606.10 VBB33657.1 - 8.5 4.9 18.0 12 4.4 18.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTG PF07742.12 VBB33659.1 - 9.9e-22 77.0 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 BTG family Synaphin PF05835.12 VBB33660.1 - 1.2e-37 129.4 12.8 1.4e-37 129.1 12.8 1.0 1 0 0 1 1 1 1 Synaphin protein Mlp PF03304.13 VBB33660.1 - 0.083 13.1 1.7 0.29 11.3 0.2 2.3 3 0 0 3 3 3 0 Mlp lipoprotein family Atrophin-1 PF03154.15 VBB33660.1 - 1.6 7.0 4.1 1.6 6.9 4.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family MAM PF00629.23 VBB33661.1 - 8.1e-07 29.1 0.2 0.00055 19.9 0.4 3.0 2 1 0 2 2 2 2 MAM domain, meprin/A5/mu GSH_synth_ATP PF03917.17 VBB33662.1 - 3.9e-114 381.3 0.0 4.5e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 VBB33662.1 - 1.4e-30 105.8 0.1 1.5e-29 102.5 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic glutathione synthase RNA_pol_Rpb1_4 PF05000.17 VBB33665.1 - 0.0098 15.8 0.5 4.9 7.2 0.3 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 4 Lactamase_B PF00753.27 VBB33665.1 - 0.016 15.2 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Trypsin PF00089.26 VBB33666.1 - 8.8e-07 29.0 0.0 9.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin COMP PF11598.8 VBB33668.1 - 0.18 12.3 0.6 0.46 11.0 0.6 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein CDC45 PF02724.14 VBB33668.1 - 0.31 9.3 9.4 0.42 8.8 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Striatin PF08232.12 VBB33668.1 - 0.59 10.7 18.1 1.1 9.8 18.1 1.4 1 0 0 1 1 1 0 Striatin family Atg14 PF10186.9 VBB33668.1 - 1.6 7.7 11.8 2.4 7.2 11.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Neur_chan_memb PF02932.16 VBB33668.1 - 4 7.4 4.8 6.3 6.8 4.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 VBB33668.1 - 7.7 6.2 19.0 12 5.6 19.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Na_K-ATPase PF00287.18 VBB33669.1 - 2.2e-72 243.6 0.0 2.5e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DUF2417 PF10329.9 VBB33669.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Neur_chan_memb PF02932.16 VBB33670.1 - 5.9e-06 26.5 0.2 1e-05 25.7 0.2 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GCIP PF13324.6 VBB33670.1 - 0.094 12.3 0.3 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ribosomal_L30_N PF08079.12 VBB33670.1 - 2 8.7 4.7 0.34 11.2 0.6 1.7 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Toprim_C_rpt PF13368.6 VBB33671.1 - 0.23 11.5 5.9 2.7 8.0 0.2 3.5 1 1 2 3 3 3 0 Topoisomerase C-terminal repeat TDP43_N PF18694.1 VBB33672.1 - 2.8e-19 68.7 0.0 4.5e-19 68.1 0.0 1.3 1 1 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain GATA PF00320.27 VBB33673.1 - 2e-14 52.9 3.8 3.5e-14 52.1 3.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 VBB33673.1 - 0.02 14.4 0.5 0.04 13.4 0.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding ArfGap PF01412.18 VBB33673.1 - 0.047 13.8 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Prim_Zn_Ribbon PF08273.12 VBB33673.1 - 0.12 12.7 1.7 0.27 11.5 1.7 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase ShK PF01549.24 VBB33674.1 - 4.6e-21 75.1 63.1 4e-08 33.7 7.5 5.7 6 0 0 6 6 6 5 ShK domain-like Tudor_2 PF18104.1 VBB33675.1 - 0.44 10.3 2.2 1.2 8.8 2.2 1.7 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain zf-CCCH_2 PF14608.6 VBB33677.1 - 0.00052 20.4 2.9 0.00052 20.4 2.9 3.5 4 0 0 4 4 4 1 RNA-binding, Nab2-type zinc finger YidD PF01809.18 VBB33677.1 - 0.44 10.5 3.7 0.8 9.6 2.5 2.0 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor DUF4834 PF16118.5 VBB33677.1 - 1.7 9.7 12.5 0.23 12.4 2.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ldl_recept_a PF00057.18 VBB33678.1 - 3.2e-51 171.3 123.2 3.3e-11 43.2 12.2 7.1 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 VBB33678.1 - 5.8e-13 49.1 10.5 0.0012 19.3 0.0 5.4 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B EF-hand_1 PF00036.32 VBB33679.1 - 3.3e-41 135.8 10.8 3.3e-10 38.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB33679.1 - 3e-33 114.1 5.1 2.7e-17 63.0 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB33679.1 - 8.3e-32 108.8 12.7 7.9e-13 48.0 2.2 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 VBB33679.1 - 6.2e-30 100.5 3.6 4.6e-09 35.5 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 VBB33679.1 - 8.6e-23 78.8 6.1 4.5e-06 25.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 VBB33679.1 - 1.9e-12 47.3 0.1 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 VBB33679.1 - 1.2e-06 28.4 1.8 0.03 14.3 0.5 3.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 VBB33679.1 - 0.00024 21.1 0.0 3.2 7.9 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 VBB33679.1 - 0.0004 21.2 0.1 0.0021 18.9 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 VBB33679.1 - 0.00094 19.2 1.7 0.0014 18.7 0.3 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 VBB33679.1 - 0.001 19.4 0.1 1.6 9.1 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 VBB33679.1 - 0.0079 16.4 0.5 0.49 10.6 0.1 3.0 1 1 1 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 VBB33679.1 - 0.016 15.1 0.7 12 5.7 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein PY_rept_46 PF09689.10 VBB33679.1 - 0.031 14.8 0.7 5.8 7.6 0.7 2.6 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Phage_TAC_12 PF12363.8 VBB33679.1 - 0.067 13.6 0.0 0.87 10.0 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC PMBR PF09373.10 VBB33679.1 - 0.084 13.1 0.0 1e+02 3.3 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat EF-hand_10 PF14788.6 VBB33679.1 - 6.4 6.7 8.4 0.54 10.2 0.3 3.2 4 1 1 5 5 5 0 EF hand Gal-bind_lectin PF00337.22 VBB33680.1 - 7.7e-41 138.8 0.0 2.2e-37 127.5 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin tRNA_anti-codon PF01336.25 VBB33680.1 - 0.0003 20.7 0.0 0.0058 16.6 0.1 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Pkinase PF00069.25 VBB33681.1 - 1.7e-27 96.5 0.1 2.3e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33681.1 - 5e-14 52.2 0.0 6.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB33681.1 - 0.00027 19.9 0.0 0.00043 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB33681.1 - 0.023 14.1 0.3 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.12 VBB33682.1 - 3.2e-41 141.7 21.3 2.2e-31 109.3 12.5 2.9 1 1 2 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) TOPRIM_C PF16898.5 VBB33682.1 - 0.036 14.4 0.6 0.036 14.4 0.6 1.9 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM End3 PF12761.7 VBB33682.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.9 4 0 0 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 Ras PF00071.22 VBB33683.1 - 6.7e-59 198.1 0.1 7.8e-59 197.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB33683.1 - 4.9e-32 110.7 0.0 7.4e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB33683.1 - 5.9e-11 42.1 0.0 7.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB33683.1 - 8.2e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB33683.1 - 0.0001 22.2 0.1 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 VBB33683.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 VBB33683.1 - 0.0015 18.1 0.0 0.052 13.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 VBB33683.1 - 0.0047 17.3 0.0 0.0087 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 VBB33683.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 VBB33683.1 - 0.0082 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 VBB33683.1 - 0.014 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 VBB33683.1 - 0.015 14.6 0.1 0.03 13.6 0.1 1.5 2 0 0 2 2 2 0 Septin cobW PF02492.19 VBB33683.1 - 0.016 14.8 0.0 0.073 12.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 VBB33683.1 - 0.021 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 VBB33683.1 - 0.025 14.3 0.5 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 VBB33683.1 - 0.035 14.0 0.1 0.037 13.9 0.1 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 VBB33683.1 - 0.056 13.2 0.0 2.2 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 VBB33683.1 - 0.063 12.5 0.1 0.093 11.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 VBB33683.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 VBB33683.1 - 0.092 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 VBB33683.1 - 0.096 12.6 0.2 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 VBB33683.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 VBB33683.1 - 0.15 11.2 0.7 0.53 9.4 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 VBB33683.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 VBB33683.1 - 0.19 12.2 0.3 0.26 11.8 0.3 1.6 1 1 0 1 1 1 0 ABC transporter PDZ PF00595.24 VBB33684.1 - 9.8e-27 93.1 0.1 5.9e-12 45.8 0.1 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB33684.1 - 7.8e-19 67.3 0.1 8.5e-09 35.1 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB33684.1 - 6.9e-10 39.1 0.2 0.0014 18.9 0.1 2.2 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.14 VBB33684.1 - 7.2e-06 26.4 0.0 0.035 14.4 0.0 2.1 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 VBB33684.1 - 0.0064 16.4 0.1 2.7 8.0 0.0 2.5 2 1 0 2 2 2 2 Tricorn protease PDZ domain LSM14 PF12701.7 VBB33685.1 - 8.2e-30 102.7 0.2 3.4e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.10 VBB33685.1 - 1.1e-14 55.2 10.2 1.8e-14 54.4 10.2 1.4 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 VBB33685.1 - 4.1e-08 33.3 0.0 7.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3621 PF12285.8 VBB33686.1 - 0.05 14.0 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Haspin_kinase PF12330.8 VBB33687.1 - 2.7e-38 131.9 0.1 5.3e-38 130.9 0.0 1.4 1 1 1 2 2 2 1 Haspin like kinase domain RhoGEF PF00621.20 VBB33689.1 - 1.4e-21 77.5 4.9 3.6e-21 76.2 4.9 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 VBB33689.1 - 0.016 15.7 0.7 0.037 14.5 0.1 1.9 2 0 0 2 2 2 0 PH domain RBD PF02196.15 VBB33689.1 - 0.016 15.3 0.1 0.047 13.8 0.1 1.8 1 0 0 1 1 1 0 Raf-like Ras-binding domain G10 PF01125.17 VBB33689.1 - 0.027 14.2 2.7 0.033 14.0 0.6 2.1 2 0 0 2 2 2 0 G10 protein UL41A PF17591.2 VBB33689.1 - 0.08 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL41A Retrotrans_gag PF03732.17 VBB33689.1 - 0.3 11.4 2.2 22 5.4 0.2 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein H-kinase_dim PF02895.14 VBB33689.1 - 2.8 8.4 5.6 1.5e+02 2.8 4.9 3.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Motile_Sperm PF00635.26 VBB33691.1 - 6.2e-06 26.0 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PKD PF00801.20 VBB33692.1 - 6.9e-07 29.0 0.1 0.0044 16.8 0.0 2.9 2 0 0 2 2 2 2 PKD domain He_PIG PF05345.12 VBB33692.1 - 0.021 15.0 0.4 6.7 7.0 0.0 3.9 4 0 0 4 4 4 0 Putative Ig domain Y_Y_Y PF07495.13 VBB33692.1 - 0.037 14.0 0.1 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Y_Y_Y domain Xylo_C PF12529.8 VBB33694.1 - 0.014 15.1 0.5 0.033 13.8 0.5 1.8 1 0 0 1 1 1 0 Xylosyltransferase C terminal Viral_protease PF08715.10 VBB33694.1 - 0.059 12.7 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Papain like viral protease PKcGMP_CC PF16808.5 VBB33694.1 - 0.22 11.4 10.2 7 6.6 0.2 4.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 VBB33694.1 - 0.33 10.3 26.7 1.3 8.3 7.0 3.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding MADF_DNA_bdg PF10545.9 VBB33694.1 - 2.1 8.7 9.7 3.5 8.0 0.1 3.7 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Frizzled PF01534.17 VBB33696.1 - 2.1e-101 339.2 24.2 2.8e-101 338.8 24.2 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 VBB33696.1 - 7.4e-32 110.3 2.1 2.1e-31 108.8 2.1 1.8 1 0 0 1 1 1 1 Fz domain DUF261 PF03196.13 VBB33696.1 - 0.55 10.3 2.5 2.1 8.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Myotub-related PF06602.14 VBB33697.1 - 2.8e-48 164.6 2.4 5e-40 137.5 0.6 2.2 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 VBB33697.1 - 1e-05 25.3 0.0 4.1e-05 23.3 0.0 2.0 2 1 0 2 2 2 1 Myotubularin-associated protein I-set PF07679.16 VBB33698.1 - 1.6e-38 130.7 0.1 5.2e-12 45.7 0.0 5.0 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB33698.1 - 3.8e-38 129.9 0.3 2.3e-11 44.1 0.0 5.1 4 1 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 VBB33698.1 - 1e-20 73.8 0.7 8.2e-07 29.3 0.0 5.6 5 1 0 5 5 4 3 Immunoglobulin domain ig PF00047.25 VBB33698.1 - 1.1e-20 73.6 0.3 1.7e-07 31.3 0.0 4.9 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 VBB33698.1 - 1.8e-12 47.4 2.4 0.0034 17.6 0.1 5.7 5 1 1 6 6 6 2 Immunoglobulin V-set domain fn3 PF00041.21 VBB33698.1 - 2.4e-11 43.8 0.1 5.5e-05 23.4 0.0 3.3 4 0 0 4 4 4 2 Fibronectin type III domain Izumo-Ig PF16706.5 VBB33698.1 - 8.6e-06 25.7 0.0 1.7 8.8 0.0 4.0 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 VBB33698.1 - 0.00013 21.9 0.0 6.3 6.9 0.0 4.4 4 1 0 4 4 4 2 C17orf99 Ig domain Egh16-like PF11327.8 VBB33698.1 - 0.0019 18.6 0.1 0.061 13.7 0.0 2.3 2 0 0 2 2 2 1 Egh16-like virulence factor Ig_6 PF18452.1 VBB33698.1 - 0.0034 16.9 0.0 20 4.8 0.0 4.2 4 0 0 4 4 4 0 Immunoglobulin domain Ig_4 PF16680.5 VBB33698.1 - 0.013 15.7 0.4 28 5.0 0.0 4.4 5 0 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain Polyhedrin PF00738.18 VBB33698.1 - 0.053 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin UQ_con PF00179.26 VBB33699.1 - 5e-31 107.2 0.0 8.7e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 VBB33699.1 - 0.0017 18.2 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 UEV domain Imm41 PF15592.6 VBB33699.1 - 0.04 14.3 0.3 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 41 MAGE PF01454.19 VBB33700.1 - 1.5e-08 34.6 0.0 2.2e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 MAGE family CCDC85 PF10226.9 VBB33700.1 - 0.00074 19.3 1.1 0.001 18.8 1.1 1.2 1 0 0 1 1 1 1 CCDC85 family Ribosomal_L50 PF10501.9 VBB33701.1 - 1.9e-12 47.3 0.1 4.2e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S PXB PF12828.7 VBB33701.1 - 0.0079 16.2 0.5 0.18 11.8 0.1 2.2 2 0 0 2 2 2 1 PX-associated RPA_C PF08784.11 VBB33702.1 - 0.00047 20.8 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal DeoC PF01791.9 VBB33703.1 - 7.5e-07 29.0 0.0 8e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Cytochrome_CBB3 PF13442.6 VBB33703.1 - 0.084 13.2 0.1 0.099 13.0 0.1 1.3 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Pyr_redox_2 PF07992.14 VBB33704.1 - 1.3e-27 96.8 0.1 4e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 VBB33704.1 - 8.2e-07 28.9 0.5 7.2e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 Rubredoxin NAD+ reductase C-terminal domain K_oxygenase PF13434.6 VBB33704.1 - 0.00013 21.3 0.3 0.00037 19.7 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 VBB33704.1 - 0.0095 16.4 1.7 5.1 7.6 0.1 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 VBB33704.1 - 0.012 16.2 1.2 7.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 VBB33704.1 - 0.099 11.9 0.4 24 4.0 0.0 3.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 VBB33704.1 - 0.15 11.1 1.9 8 5.4 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain PDZ_2 PF13180.6 VBB33706.1 - 2.7e-07 30.8 0.0 0.0035 17.6 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB33706.1 - 4.1e-06 26.5 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB33706.1 - 0.00083 19.7 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 VBB33706.1 - 0.0059 16.9 1.0 0.022 15.0 0.3 2.1 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 VBB33706.1 - 0.069 13.5 0.6 0.35 11.3 0.1 2.4 2 2 0 2 2 2 0 PDZ domain DUF883 PF05957.13 VBB33706.1 - 0.15 12.6 0.1 0.37 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Tricorn_PDZ PF14685.6 VBB33706.1 - 0.18 11.8 0.0 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain TPR_1 PF00515.28 VBB33707.1 - 3.7e-25 86.6 6.1 2.4e-06 27.1 0.4 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33707.1 - 9.8e-22 75.3 4.3 3.2e-05 23.7 0.7 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33707.1 - 6.1e-20 69.7 5.2 0.00011 22.1 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33707.1 - 5.6e-15 55.6 2.7 0.00012 22.5 0.3 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 VBB33707.1 - 2.6e-14 53.5 0.6 6.7e-06 26.7 1.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 VBB33707.1 - 1.8e-13 49.8 12.5 2.4e-05 24.4 0.5 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 VBB33707.1 - 2.2e-13 50.3 9.9 0.0072 16.6 0.0 4.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 VBB33707.1 - 2.9e-13 49.3 3.0 7.5e-05 22.3 0.5 4.6 2 2 3 5 5 5 3 TPR repeat TPR_14 PF13428.6 VBB33707.1 - 1.1e-10 41.3 0.2 0.027 15.3 0.1 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 VBB33707.1 - 9.7e-10 38.0 10.2 0.016 15.0 0.5 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 VBB33707.1 - 6.1e-09 35.3 2.2 0.069 13.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33707.1 - 7.5e-09 35.7 5.6 0.0012 19.1 0.1 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 VBB33707.1 - 7.3e-07 29.4 0.9 0.16 12.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 VBB33707.1 - 5.5e-05 23.2 0.4 0.45 10.7 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 VBB33707.1 - 0.0053 16.8 0.3 2.5 8.2 0.2 2.3 1 1 1 2 2 2 2 Rapsyn N-terminal myristoylation and linker region Coatomer_E PF04733.14 VBB33707.1 - 0.0066 15.9 0.4 3 7.2 0.0 2.8 1 1 2 3 3 3 2 Coatomer epsilon subunit TPR_15 PF13429.6 VBB33707.1 - 0.0071 15.6 2.8 0.036 13.3 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB33707.1 - 0.013 15.6 1.9 0.21 11.7 0.0 3.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Wzy_C_2 PF11846.8 VBB33707.1 - 0.02 14.8 0.4 0.21 11.5 0.3 2.3 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal tRNA-synt_His PF13393.6 VBB33708.1 - 6.1e-37 127.5 0.0 3.4e-36 125.1 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 VBB33708.1 - 2.6e-05 24.2 0.1 8.3e-05 22.6 0.1 1.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 VBB33708.1 - 0.00022 20.4 0.0 0.0031 16.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 VBB33708.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PAM2 PF07145.15 VBB33709.1 - 0.00017 21.0 1.4 0.00042 19.8 1.4 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region ZapB PF06005.12 VBB33710.1 - 0.0059 17.0 0.2 0.0059 17.0 0.2 11.7 7 4 3 10 10 10 3 Cell division protein ZapB CENP-F_leu_zip PF10473.9 VBB33710.1 - 0.0069 16.4 11.8 0.0069 16.4 11.8 10.9 5 5 7 12 12 12 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HLH PF00010.26 VBB33712.1 - 7.2e-13 48.3 5.6 9.2e-13 47.9 5.6 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.24 VBB33715.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB33715.1 - 0.086 11.7 0.9 0.14 11.0 0.1 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Peptidase_C1 PF00112.23 VBB33717.1 - 3.7e-21 76.2 0.3 4.5e-21 75.9 0.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Na_H_Exchanger PF00999.21 VBB33718.1 - 3.3e-73 246.7 37.0 3.8e-73 246.5 37.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PHD PF00628.29 VBB33720.1 - 0.001 18.9 9.0 0.0022 17.9 9.0 1.6 1 0 0 1 1 1 1 PHD-finger SUIM_assoc PF16619.5 VBB33720.1 - 0.36 10.9 0.1 0.36 10.9 0.1 4.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-RING_2 PF13639.6 VBB33720.1 - 0.96 9.8 9.3 6.8 7.1 9.2 2.4 1 1 0 1 1 1 0 Ring finger domain I-set PF07679.16 VBB33721.1 - 2.4e-142 463.4 1.3 3.9e-16 58.9 0.0 11.1 11 0 0 11 11 11 11 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB33721.1 - 4.9e-117 382.7 9.2 1.3e-13 51.4 0.1 11.1 11 0 0 11 11 11 10 Immunoglobulin domain Ig_2 PF13895.6 VBB33721.1 - 1.5e-88 291.2 0.3 2.2e-09 37.5 0.0 11.1 11 0 0 11 11 11 11 Immunoglobulin domain ig PF00047.25 VBB33721.1 - 7.3e-74 244.0 0.0 1.1e-09 38.3 0.0 11.6 11 0 0 11 11 11 10 Immunoglobulin domain V-set PF07686.17 VBB33721.1 - 1.6e-27 95.8 9.7 0.17 12.0 0.0 15.6 12 6 3 15 15 14 6 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB33721.1 - 7.1e-26 90.4 0.0 0.02 15.3 0.0 10.0 10 0 0 10 10 10 6 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 VBB33721.1 - 3.7e-24 84.6 0.5 0.009 16.1 0.0 9.4 10 0 0 10 10 10 5 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 VBB33721.1 - 5.7e-22 77.8 0.3 0.012 15.8 0.0 10.4 10 1 0 10 10 10 4 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 VBB33721.1 - 9.9e-21 73.1 0.0 0.02 14.4 0.0 8.4 8 0 0 8 8 8 6 Immunoglobulin domain C1-set PF07654.15 VBB33721.1 - 1.4e-17 63.9 1.1 0.025 14.9 0.1 10.0 11 0 0 11 11 10 3 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 VBB33721.1 - 1.5e-08 34.6 0.4 1.6 8.8 0.0 7.4 8 0 0 8 8 7 2 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 VBB33721.1 - 3.6e-08 33.5 2.7 0.25 11.3 0.0 6.7 6 1 0 6 6 6 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 VBB33721.1 - 5.1e-07 29.4 1.6 0.93 9.3 0.0 7.5 9 0 0 9 9 9 1 Adenovirus E3 region protein CR1 Herpes_gE PF02480.16 VBB33721.1 - 1.2e-05 24.3 0.0 2.5 6.8 0.0 4.6 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein E ACAS_N PF16177.5 VBB33721.1 - 0.034 14.1 0.1 4.4 7.3 0.0 4.1 6 0 0 6 6 5 0 Acetyl-coenzyme A synthetase N-terminus BslA PF17735.1 VBB33721.1 - 0.25 11.3 0.7 93 3.0 0.0 4.6 7 0 0 7 7 7 0 Biofilm surface layer A DAGK_acc PF00609.19 VBB33722.1 - 2.3e-53 180.8 0.0 4e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain RA PF00788.23 VBB33722.1 - 1.5e-25 89.7 0.7 2.7e-11 43.9 0.1 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DAGK_cat PF00781.24 VBB33722.1 - 3.3e-23 81.7 0.0 6.5e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 VBB33722.1 - 5.8e-08 32.5 8.8 1.1e-07 31.6 8.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TUG-UBL1 PF11470.8 VBB33722.1 - 0.006 16.8 0.0 2.4 8.5 0.0 2.6 2 0 0 2 2 2 2 TUG ubiquitin-like domain Desmo_N PF06771.11 VBB33722.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus RRM_1 PF00076.22 VBB33723.1 - 3.6e-17 61.9 0.3 7.4e-17 60.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 VBB33723.1 - 0.00013 21.5 0.0 0.00036 20.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB33723.1 - 0.0019 18.0 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF2615 PF11027.8 VBB33730.1 - 0.0083 16.2 0.1 0.0099 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) CLTH PF10607.9 VBB33731.1 - 3.5e-06 27.0 1.2 7.3e-06 25.9 1.2 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 VBB33731.1 - 0.00098 19.1 0.7 0.0023 17.9 0.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 VBB33731.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger GyrB_insert PF18053.1 VBB33731.1 - 0.023 14.6 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain ELYS PF13934.6 VBB33731.1 - 0.034 14.1 0.3 0.37 10.7 0.1 2.4 2 1 0 2 2 2 0 Nuclear pore complex assembly DNA_pol_D_N PF18018.1 VBB33731.1 - 0.086 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain WD40 PF00400.32 VBB33732.1 - 1.3e-39 133.4 23.7 3.6e-08 33.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB33732.1 - 1.2e-12 48.0 0.1 0.072 13.4 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB33732.1 - 5e-06 26.0 0.0 0.69 9.2 0.0 3.6 2 2 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 VBB33732.1 - 5.6e-06 26.4 0.0 0.0082 16.0 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 VBB33732.1 - 0.00025 20.1 0.0 0.36 9.7 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RraA-like PF03737.15 VBB33732.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Aldolase/RraA Rsm22 PF09243.10 VBB33733.1 - 7.8e-21 74.6 1.0 9e-12 44.8 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Patched PF02460.18 VBB33734.1 - 2e-05 22.9 21.6 2.6e-05 22.5 21.6 1.1 1 0 0 1 1 1 1 Patched family Lipocalin PF00061.23 VBB33737.1 - 5.4e-12 46.1 0.2 6e-12 46.0 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 VBB33737.1 - 0.022 14.7 0.2 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Adeno_E3_CR2 PF02439.15 VBB33738.1 - 4.1 7.3 6.1 0.66 9.8 1.5 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Lsm_interact PF05391.11 VBB33739.1 - 0.83 9.2 4.4 3.2 7.4 4.4 2.1 1 0 0 1 1 1 0 Lsm interaction motif DUF4634 PF15465.6 VBB33739.1 - 1.1 9.6 4.6 2 8.8 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) Collectrin PF16959.5 VBB33740.1 - 0.0018 18.0 1.6 0.003 17.4 1.6 1.3 1 0 0 1 1 1 1 Renal amino acid transporter ArsP_1 PF03773.13 VBB33740.1 - 0.018 14.2 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Predicted permease DUF3629 PF12302.8 VBB33740.1 - 0.046 13.2 0.2 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) Mid2 PF04478.12 VBB33740.1 - 3.5 7.5 8.8 5.2 6.9 8.2 1.5 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor SIR2 PF02146.17 VBB33741.1 - 3.2e-24 85.8 0.3 8.2e-18 64.9 0.1 2.6 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 VBB33741.1 - 0.014 15.2 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Branch PF02485.21 VBB33742.1 - 1e-20 74.3 0.1 1.8e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Xylo_C PF12529.8 VBB33742.1 - 4.2e-10 39.5 0.1 6.2e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal MCM_bind PF09739.9 VBB33743.1 - 1.5e-26 93.0 6.3 8.9e-25 87.2 4.6 3.0 2 1 0 2 2 2 1 Mini-chromosome maintenance replisome factor Hemolysin_N PF12563.8 VBB33743.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Hemolytic toxin N terminal E_raikovi_mat PF06360.11 VBB33743.1 - 5 7.6 4.7 1.8 9.1 0.8 2.1 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone ApoL PF05461.11 VBB33745.1 - 1.6e-09 37.6 0.0 7e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 Apolipoprotein L Mce4_CUP1 PF11887.8 VBB33745.1 - 0.00078 19.0 0.4 0.0013 18.3 0.4 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF3482 PF11981.8 VBB33745.1 - 0.56 9.5 3.7 0.32 10.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) DUF4838 PF16126.5 VBB33747.1 - 1.4e-09 37.7 0.8 5.2e-09 35.9 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4838) Glyco_hydro_20 PF00728.22 VBB33747.1 - 3.7e-09 36.4 0.1 7.5e-09 35.4 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Na_sulph_symp PF00939.19 VBB33748.1 - 1.6e-16 60.4 11.0 1.7e-16 60.3 11.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 VBB33748.1 - 1.3e-08 34.5 9.7 1.4e-08 34.3 9.7 1.1 1 0 0 1 1 1 1 Citrate transporter DcuA_DcuB PF03605.14 VBB33748.1 - 0.00065 18.7 6.3 0.00079 18.4 6.3 1.0 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DcuC PF03606.15 VBB33748.1 - 0.0052 15.3 7.0 0.0058 15.1 7.0 1.1 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier Rsm22 PF09243.10 VBB33749.1 - 2.5e-08 33.5 0.1 3.4e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 VWA_2 PF13519.6 VBB33750.1 - 0.0035 18.0 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain CHASE8 PF17152.4 VBB33751.1 - 0.022 15.0 0.8 0.052 13.8 0.3 1.8 1 1 1 2 2 2 0 Periplasmic sensor domain DUF4639 PF15479.6 VBB33751.1 - 0.056 12.4 5.9 0.064 12.2 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) CENP-K PF11802.8 VBB33751.1 - 2.8 7.5 16.5 5.9 6.4 16.5 1.6 1 1 0 1 1 1 0 Centromere-associated protein K SAE2 PF08573.10 VBB33751.1 - 2.8 9.1 9.0 3.3 8.9 9.0 1.1 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus UNC-93 PF05978.16 VBB33752.1 - 3.6e-33 114.5 14.7 6.4e-33 113.7 14.7 1.4 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 VBB33752.1 - 0.00038 19.5 22.5 0.0011 18.0 11.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily WW PF00397.26 VBB33753.1 - 2.7e-25 88.1 33.5 5.8e-10 39.1 6.9 3.9 4 0 0 4 4 4 3 WW domain FF PF01846.19 VBB33753.1 - 1e-23 83.2 6.3 1.8e-11 44.0 0.9 2.7 2 0 0 2 2 2 2 FF domain Glyco_hyd_101C PF17451.2 VBB33753.1 - 0.0014 18.9 5.9 0.43 10.9 0.1 3.5 3 0 0 3 3 3 2 Glycosyl hydrolase 101 beta sandwich domain EF-hand_2 PF09068.11 VBB33756.1 - 5e-34 117.1 1.0 1.1e-33 116.0 1.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 VBB33756.1 - 2.2e-24 85.7 0.0 6e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 VBB33756.1 - 6.4e-10 38.7 8.3 1.6e-09 37.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 VBB33756.1 - 0.00025 21.3 5.6 0.00025 21.3 5.6 2.0 2 0 0 2 2 2 1 C1 domain DUF812 PF05667.11 VBB33756.1 - 0.00059 18.8 1.2 0.0008 18.4 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 VBB33756.1 - 0.0017 17.3 6.8 0.0029 16.6 6.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein RasGAP_C PF03836.15 VBB33756.1 - 0.014 15.6 1.4 0.014 15.6 1.4 1.9 2 0 0 2 2 2 0 RasGAP C-terminus FTA4 PF13093.6 VBB33756.1 - 0.02 14.8 2.7 0.037 13.9 2.7 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FapA PF03961.13 VBB33756.1 - 0.16 10.5 4.7 0.25 9.9 4.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A mRNA_cap_enzyme PF01331.19 VBB33757.1 - 2.7e-66 223.1 0.2 4.2e-66 222.5 0.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 VBB33757.1 - 3e-19 69.6 0.0 6.3e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 VBB33757.1 - 8e-12 45.1 0.0 2.4e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 VBB33757.1 - 8.6e-08 32.1 0.0 7.2e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase3 PF13350.6 VBB33757.1 - 0.00067 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 VBB33757.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 VBB33757.1 - 0.049 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Sp38 PF07354.12 VBB33758.1 - 0.14 11.6 0.8 0.21 11.0 0.8 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) P-mevalo_kinase PF04275.14 VBB33759.1 - 1.3e-36 124.9 0.0 2.4e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase SecE PF00584.20 VBB33759.1 - 3.7e-11 42.8 0.0 7.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DotA PF11388.8 VBB33759.1 - 0.04 14.1 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 Phagosome trafficking protein DotA LCIB_C_CA PF18599.1 VBB33760.1 - 0.17 11.1 0.1 0.2 10.9 0.1 1.0 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Acyltransferase PF01553.21 VBB33761.1 - 3e-25 88.4 0.0 4e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 VBB33761.1 - 1.6e-10 40.9 0.1 3.7e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus 4F5 PF04419.14 VBB33762.1 - 9.2e-11 42.4 7.5 9.2e-11 42.4 7.5 2.4 2 1 0 2 2 2 1 4F5 protein family DUF4574 PF15141.6 VBB33762.1 - 2.5 8.1 6.7 3.4 7.6 6.7 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SMN PF06003.12 VBB33763.1 - 0.51 9.5 8.6 0.084 12.1 3.9 1.9 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) Ephrin_rec_like PF07699.13 VBB33764.1 - 2.8e-06 27.0 35.1 3.4e-05 23.5 5.5 4.9 3 2 1 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 VBB33764.1 - 0.00011 22.1 27.2 0.027 14.4 0.6 5.1 3 2 3 6 6 6 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 VBB33764.1 - 1.4 9.4 27.6 1.4 9.4 0.8 6.0 5 1 0 5 5 5 0 TNFR/NGFR cysteine-rich region PHR PF08005.12 VBB33765.1 - 6.5e-09 36.6 0.7 1.7e-07 32.1 0.1 2.1 2 0 0 2 2 2 1 PHR domain NUC205 PF08168.11 VBB33765.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NUC205 domain Glycos_transf_1 PF00534.20 VBB33766.1 - 1.3e-36 125.7 0.1 2.3e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 VBB33766.1 - 5.3e-17 62.5 0.0 9.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 VBB33766.1 - 4.7e-11 43.0 0.2 0.00025 21.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 VBB33766.1 - 8.9e-10 38.8 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 VBB33766.1 - 2.1e-05 25.0 0.0 0.16 12.4 0.0 2.5 2 1 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_4_5 PF16994.5 VBB33766.1 - 0.0058 16.3 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl-transferase family 4 AhpC-TSA PF00578.21 VBB33767.1 - 1.2e-39 135.0 0.0 1.7e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB33767.1 - 5.5e-19 68.3 0.0 8.1e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Pkinase_Tyr PF07714.17 VBB33768.1 - 2.6e-93 312.0 0.0 3.8e-93 311.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB33768.1 - 3.5e-48 164.3 0.0 6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 VBB33768.1 - 2e-17 63.9 0.0 3.7e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 VBB33768.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4381 PF14316.6 VBB33768.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SAM_2 PF07647.17 VBB33768.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNF PF00209.18 VBB33769.1 - 9.4e-41 140.1 4.4 1.3e-40 139.6 4.4 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Dicty_REP PF05086.12 VBB33769.1 - 4.6 5.1 7.5 5.7 4.8 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sugar_tr PF00083.24 VBB33770.1 - 1.9e-40 139.1 18.6 2.8e-40 138.6 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB33770.1 - 7.7e-14 51.4 31.1 2e-12 46.7 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RepB PF07506.11 VBB33771.1 - 0.016 15.3 0.2 0.031 14.4 0.2 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein TAFII28 PF04719.14 VBB33771.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Zip PF02535.22 VBB33772.1 - 9.5e-37 127.0 9.1 1.1e-36 126.7 9.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1673 PF07895.11 VBB33772.1 - 0.28 10.9 3.4 0.36 10.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Endonuclease_NS PF01223.23 VBB33773.1 - 1.1e-51 175.8 0.0 7.6e-50 169.8 0.0 2.3 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease HNHc_6 PF16784.5 VBB33773.1 - 0.013 15.1 0.3 0.038 13.6 0.2 1.6 1 1 1 2 2 2 0 Putative HNHc nuclease DUF1493 PF07377.12 VBB33773.1 - 0.022 15.2 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Endonuclea_NS_2 PF13930.6 VBB33773.1 - 0.033 14.3 0.3 0.18 11.9 0.3 2.0 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease IRF-2BP1_2 PF11261.8 VBB33774.1 - 2.3e-33 113.6 3.8 3.9e-33 112.8 3.8 1.4 1 0 0 1 1 1 1 Interferon regulatory factor 2-binding protein zinc finger TSA PF03249.13 VBB33774.1 - 0.91 8.2 5.5 1.5 7.5 5.5 1.3 1 0 0 1 1 1 0 Type specific antigen TFIIA PF03153.13 VBB33774.1 - 2.1 8.2 8.6 2.8 7.9 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 VBB33775.1 - 4.1e-61 206.6 0.0 9.7e-61 205.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33775.1 - 1.5e-24 86.7 1.3 5.8e-23 81.5 1.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Haspin_kinase PF12330.8 VBB33775.1 - 0.00026 20.1 0.1 0.00041 19.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Acyl-CoA_dh_M PF02770.19 VBB33775.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain UPAR_LY6_2 PF16975.5 VBB33777.1 - 0.00026 21.1 1.9 0.00026 21.1 1.9 1.6 2 0 0 2 2 2 1 Ly6/PLAUR domain-containing protein 6, Lypd6 GATA PF00320.27 VBB33778.1 - 7.8e-13 47.8 7.7 1.6e-12 46.8 7.7 1.6 1 0 0 1 1 1 1 GATA zinc finger eIF-5_eIF-2B PF01873.17 VBB33778.1 - 0.0073 16.2 0.7 0.014 15.3 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Ribosomal_L37ae PF01780.19 VBB33778.1 - 0.072 13.2 0.9 0.16 12.0 0.9 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family Elf1 PF05129.13 VBB33778.1 - 0.084 12.9 1.2 0.23 11.5 1.2 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2387 PF09526.10 VBB33778.1 - 0.09 12.9 1.0 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF4916 PF16262.5 VBB33778.1 - 0.19 11.2 0.2 0.26 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) Syntaxin PF00804.25 VBB33779.1 - 6e-32 111.0 12.1 7.5e-32 110.6 12.1 1.1 1 0 0 1 1 1 1 Syntaxin HeLo PF14479.6 VBB33779.1 - 0.054 13.3 4.5 0.035 13.9 1.7 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation Fez1 PF06818.15 VBB33779.1 - 0.067 13.6 4.8 1.8 9.0 0.0 2.4 1 1 0 2 2 2 0 Fez1 Microvir_H PF04687.12 VBB33779.1 - 0.077 12.4 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) eIF-5_eIF-2B PF01873.17 VBB33779.1 - 0.26 11.2 1.4 9.7 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 EGF_CA PF07645.15 VBB33780.1 - 2.2e-48 162.2 152.1 1.4e-07 31.6 3.0 14.1 11 3 2 13 13 13 11 Calcium-binding EGF domain VWA PF00092.28 VBB33780.1 - 2.8e-42 144.9 0.2 4.1e-42 144.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 VBB33780.1 - 1.5e-36 124.2 133.4 7.6e-05 22.9 5.4 13.8 13 0 0 13 13 13 12 EGF-like domain hEGF PF12661.7 VBB33780.1 - 1.9e-36 123.4 106.9 2.9e-05 24.5 3.6 14.9 13 1 0 13 13 13 11 Human growth factor-like EGF EGF_3 PF12947.7 VBB33780.1 - 2e-35 120.7 152.8 2.7e-05 24.3 4.0 14.0 13 1 0 13 13 13 11 EGF domain VWA_2 PF13519.6 VBB33780.1 - 1.3e-15 58.0 0.1 2.1e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Plasmod_Pvs28 PF06247.11 VBB33780.1 - 5.5e-13 49.0 122.8 0.00055 20.2 2.1 13.5 13 0 0 13 13 13 9 Pvs28 EGF domain cEGF PF12662.7 VBB33780.1 - 4e-12 45.8 96.7 0.0074 16.2 0.3 13.8 12 2 0 12 12 12 9 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 VBB33780.1 - 5.4e-12 45.6 110.1 0.0018 18.3 4.0 12.8 12 0 0 12 12 12 7 MSP1 EGF domain 1 FXa_inhibition PF14670.6 VBB33780.1 - 9.7e-11 41.8 137.5 0.089 13.1 2.0 13.7 11 2 2 13 13 13 10 Coagulation Factor Xa inhibitory site GBP_PSP PF02425.15 VBB33780.1 - 0.00093 18.8 1.5 0.00093 18.8 1.5 3.0 2 0 0 2 2 1 1 Paralytic/GBP/PSP peptide VWA_CoxE PF05762.14 VBB33780.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Pkinase_Tyr PF07714.17 VBB33781.1 - 2.5e-70 236.7 0.0 4e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB33781.1 - 1.4e-41 142.6 0.0 2.9e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 VBB33781.1 - 7.2e-09 35.6 0.0 1.9e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.14 VBB33781.1 - 0.076 12.4 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L35p PF01632.19 VBB33782.1 - 0.00015 22.2 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 PDZ_2 PF13180.6 VBB33785.1 - 1.1e-09 38.4 0.3 0.00088 19.6 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 VBB33785.1 - 6.9e-07 29.0 0.4 0.0032 17.3 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB33785.1 - 3.2e-06 27.4 0.4 0.11 12.9 0.1 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 VBB33785.1 - 0.0059 16.6 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain DUF1977 PF09320.11 VBB33786.1 - 2e-29 101.9 0.1 6.5e-29 100.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 VBB33786.1 - 4.7e-23 81.1 1.3 1.2e-22 79.8 1.3 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 VBB33786.1 - 0.021 14.9 0.0 0.51 10.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33786.1 - 0.089 12.7 0.4 7.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Tmemb_cc2 PF10267.9 VBB33786.1 - 0.21 10.7 3.1 0.1 11.7 0.7 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein BRO1 PF03097.18 VBB33787.1 - 4.3e-92 308.9 0.9 4.3e-92 308.9 0.9 1.9 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 VBB33787.1 - 5.6e-28 98.1 6.9 5.6e-28 98.1 6.9 2.4 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV BioW PF03744.13 VBB33787.1 - 0.0082 15.7 0.2 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 6-carboxyhexanoate--CoA ligase Pkinase PF00069.25 VBB33788.1 - 4.5e-15 55.7 0.0 7.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB33788.1 - 1.7e-10 40.6 0.0 3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB33788.1 - 0.053 12.8 0.2 3.5 6.9 0.2 2.3 2 0 0 2 2 2 0 Kinase-like DUF4411 PF14367.6 VBB33789.1 - 0.0068 16.3 3.3 0.01 15.8 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4411) HlyD_D23 PF16576.5 VBB33789.1 - 0.02 14.1 11.9 0.026 13.7 11.9 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion dsRBD2 PF17842.1 VBB33789.1 - 0.029 14.6 4.4 0.035 14.3 4.4 1.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 RskA PF10099.9 VBB33789.1 - 0.051 13.9 2.9 0.052 13.8 2.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA KfrA_N PF11740.8 VBB33789.1 - 0.058 14.1 14.0 0.082 13.6 14.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Pex14_N PF04695.13 VBB33789.1 - 0.086 13.5 16.0 0.12 13.1 16.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR1 PF08505.10 VBB33789.1 - 0.1 12.9 16.6 0.13 12.6 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Connexin PF00029.19 VBB33789.1 - 0.1 12.4 3.5 0.13 12.0 3.5 1.2 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 VBB33789.1 - 0.19 10.0 17.9 0.19 10.0 17.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 VBB33789.1 - 0.27 11.2 30.4 0.32 10.9 30.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 VBB33789.1 - 0.28 10.7 4.9 0.31 10.5 4.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 VBB33789.1 - 0.31 10.4 9.1 0.32 10.3 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Piezo_RRas_bdg PF12166.8 VBB33789.1 - 0.33 10.2 10.4 0.38 10.0 10.4 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain DUF4199 PF13858.6 VBB33789.1 - 0.37 11.2 3.5 0.48 10.8 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Glyco_transf_41 PF13844.6 VBB33789.1 - 0.45 8.9 5.9 0.51 8.7 5.9 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 Suf PF05843.14 VBB33789.1 - 0.45 10.4 12.5 0.59 10.1 12.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PepSY_TM PF03929.16 VBB33789.1 - 0.5 10.0 2.8 0.54 9.9 2.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region 5_nucleotid PF05761.14 VBB33789.1 - 0.55 9.1 9.8 0.65 8.8 9.8 1.0 1 0 0 1 1 1 0 5' nucleotidase family Bud13 PF09736.9 VBB33789.1 - 0.88 10.0 10.7 1.3 9.4 10.7 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF4175 PF13779.6 VBB33789.1 - 0.88 7.4 21.7 0.9 7.4 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 VBB33789.1 - 1.2 7.8 9.6 1.3 7.7 9.6 1.1 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 VBB33789.1 - 1.4 7.6 18.7 1.6 7.5 18.7 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FTZ PF03867.14 VBB33789.1 - 1.6 8.2 13.1 2 7.9 13.1 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region LMBR1 PF04791.16 VBB33789.1 - 1.8 7.4 10.0 2 7.2 10.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein O-antigen_lig PF13425.6 VBB33789.1 - 2.7 6.7 4.7 2.9 6.6 4.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Exonuc_VII_L PF02601.15 VBB33789.1 - 2.8 7.4 15.0 3.2 7.2 15.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit 7tm_7 PF08395.12 VBB33789.1 - 3 7.0 12.3 4.7 6.3 12.3 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Neur_chan_memb PF02932.16 VBB33789.1 - 3.1 7.8 7.4 3.7 7.5 7.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 VBB33789.1 - 3.5 7.3 8.3 4.5 7.0 8.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GTA_holin_3TM PF11351.8 VBB33789.1 - 4.2 7.9 7.6 6.9 7.2 7.6 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release TssO PF17561.2 VBB33789.1 - 4.4 7.4 15.0 5 7.2 14.4 1.3 1 1 0 1 1 1 0 Type VI secretion system, TssO CSG2 PF16965.5 VBB33789.1 - 4.7 6.1 6.3 5.1 5.9 6.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Band_3_cyto PF07565.13 VBB33789.1 - 5 6.8 15.1 6.5 6.5 15.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Y_phosphatase PF00102.27 VBB33790.1 - 1.1e-47 162.6 1.0 1.5e-47 162.2 1.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB33790.1 - 6.8e-05 22.7 2.2 0.00073 19.4 0.1 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB33790.1 - 0.016 15.2 0.2 0.03 14.3 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family MRPL52 PF18699.1 VBB33791.1 - 1.5e-27 95.6 0.1 2.4e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Mitoribosomal protein mL52 WD40 PF00400.32 VBB33791.1 - 5.1e-15 55.6 7.3 8.3e-05 23.3 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB33791.1 - 0.0015 18.8 0.2 0.011 16.0 0.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_28 PF00295.17 VBB33791.1 - 0.047 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 TcpS PF17456.2 VBB33791.1 - 0.062 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S NAD_kinase PF01513.21 VBB33792.1 - 2.1e-13 50.1 0.0 3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 VBB33792.1 - 0.0023 17.6 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain UQ_con PF00179.26 VBB33793.1 - 1.3e-48 164.2 0.0 1.5e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SMC_ScpB PF04079.16 VBB33795.1 - 0.031 13.9 0.0 0.037 13.7 0.0 1.0 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB PAN_1 PF00024.26 VBB33797.1 - 7.6e-17 61.1 15.9 2.9e-11 43.2 4.4 2.7 2 0 0 2 2 2 2 PAN domain TSP_1 PF00090.19 VBB33797.1 - 5.7 7.2 13.2 0.14 12.4 5.8 2.3 2 0 0 2 2 2 0 Thrombospondin type 1 domain Metallophos PF00149.28 VBB33798.1 - 1.1e-24 88.1 1.6 1.8e-24 87.4 1.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PADR1 PF08063.12 VBB33798.1 - 0.057 13.2 1.9 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 PADR1 (NUC008) domain PSI_integrin PF17205.3 VBB33798.1 - 0.059 13.1 0.5 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 Integrin plexin domain Metallophos PF00149.28 VBB33799.1 - 4.6e-06 27.3 0.0 5.6e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Patched PF02460.18 VBB33801.1 - 1.5e-14 53.1 0.5 2e-14 52.7 0.5 1.1 1 0 0 1 1 1 1 Patched family Ribosomal_L28 PF00830.19 VBB33801.1 - 0.019 15.1 0.4 0.085 13.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L28 family DUF932 PF06067.11 VBB33802.1 - 0.023 14.5 0.5 0.023 14.5 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF932) DUF3323 PF11796.8 VBB33802.1 - 0.062 13.2 0.9 0.091 12.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Fib_alpha PF08702.10 VBB33802.1 - 2.1 8.5 9.2 0.75 10.0 1.7 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 VBB33802.1 - 2.7 8.5 10.1 0.84 10.2 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Prot_ATP_OB_N PF17758.1 VBB33803.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Cyt-b5 PF00173.28 VBB33804.1 - 2.8e-13 49.8 0.2 5.3e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Neur_chan_LBD PF02931.23 VBB33805.1 - 6.4e-10 38.8 0.1 1.1e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Fun_ATP-synt_8 PF05933.13 VBB33805.1 - 0.0061 16.7 4.9 0.0061 16.7 4.9 2.4 2 1 0 2 2 2 1 Fungal ATP synthase protein 8 (A6L) DUF1700 PF08006.11 VBB33805.1 - 2.9 7.4 10.4 2.7 7.5 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) MFS_1 PF07690.16 VBB33806.1 - 5.9e-05 22.2 18.1 5.9e-05 22.2 18.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 VBB33806.1 - 0.0021 16.7 8.2 0.0021 16.7 8.2 1.9 1 1 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 VBB33806.1 - 0.04 12.8 16.0 0.016 14.1 13.7 1.5 2 0 0 2 2 2 0 Sugar (and other) transporter HMG_box PF00505.19 VBB33807.1 - 7.6e-27 93.5 2.0 1.5e-26 92.6 2.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 VBB33807.1 - 9e-10 39.0 1.2 1.6e-09 38.2 1.2 1.4 1 0 0 1 1 1 1 HMG-box domain Shadoo PF14999.6 VBB33807.1 - 0.069 13.3 0.3 0.069 13.3 0.3 2.3 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective SOXp PF12336.8 VBB33807.1 - 0.3 12.2 0.2 0.3 12.2 0.2 2.5 3 0 0 3 3 3 0 SOX transcription factor Ribosomal_60s PF00428.19 VBB33807.1 - 0.39 11.3 0.1 0.39 11.3 0.1 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein EGF PF00008.27 VBB33809.1 - 0.19 12.0 7.5 1.6 9.1 1.1 3.0 3 0 0 3 3 3 0 EGF-like domain Peptidase_M17 PF00883.21 VBB33811.1 - 8.1e-95 317.7 0.0 1e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 VBB33811.1 - 1.4e-05 25.4 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 Myb_DNA-bind_5 PF13873.6 VBB33813.1 - 7.9e-05 22.6 3.9 0.00039 20.4 0.2 3.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 VBB33813.1 - 0.043 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PhoU PF01895.19 VBB33813.1 - 0.44 11.1 3.1 1.2 9.7 0.5 2.7 3 0 0 3 3 3 0 PhoU domain Xpo1 PF08389.12 VBB33814.1 - 0.037 14.1 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 Exportin 1-like protein ERM PF00769.19 VBB33816.1 - 2.2e-05 24.4 22.3 2.2e-05 24.4 22.3 5.3 1 1 4 5 5 5 3 Ezrin/radixin/moesin family DUF1664 PF07889.12 VBB33816.1 - 0.0029 17.7 5.4 0.0029 17.7 5.4 7.5 2 1 6 9 9 9 4 Protein of unknown function (DUF1664) GAS PF13851.6 VBB33816.1 - 0.006 16.0 15.4 0.006 16.0 15.4 6.2 1 1 4 5 5 5 3 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 VBB33816.1 - 0.022 14.6 14.6 0.32 10.9 0.6 5.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 VBB33816.1 - 0.45 10.7 108.4 0.49 10.6 15.1 6.8 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Hormone_recep PF00104.30 VBB33817.1 - 4e-13 49.4 0.7 9.7e-13 48.2 0.7 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor BTB PF00651.31 VBB33818.1 - 0.00037 20.7 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SSTK-IP PF15836.5 VBB33818.1 - 0.094 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Zip PF02535.22 VBB33819.1 - 1.5e-15 57.2 0.7 1.7e-15 57.1 0.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FAM176 PF14851.6 VBB33820.1 - 6 6.5 7.0 6.3 6.5 7.0 1.1 1 0 0 1 1 1 0 FAM176 family Macoilin PF09726.9 VBB33821.1 - 0.0035 16.0 9.9 0.0035 16.0 9.9 3.6 2 1 2 4 4 4 1 Macoilin family SelP_N PF04592.14 VBB33821.1 - 0.004 16.6 25.7 0.004 16.6 25.7 2.8 3 0 0 3 3 3 1 Selenoprotein P, N terminal region DUF4746 PF15928.5 VBB33821.1 - 8 5.8 14.7 13 5.1 8.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Connexin PF00029.19 VBB33821.1 - 8.3 6.1 19.1 4.7 6.9 1.1 2.7 2 0 0 2 2 2 0 Connexin zf-ribbon_3 PF13248.6 VBB33822.1 - 0.0049 16.2 13.3 0.91 9.0 5.5 3.5 3 0 0 3 3 3 2 zinc-ribbon domain Clathrin PF00637.20 VBB33822.1 - 0.0099 15.8 0.2 0.15 11.9 0.1 2.8 1 1 0 2 2 2 1 Region in Clathrin and VPS DZR PF12773.7 VBB33822.1 - 0.039 14.0 10.4 3.3 7.8 8.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon RIC1 PF07064.13 VBB33822.1 - 0.042 13.2 0.9 4 6.8 0.0 3.1 2 1 1 3 3 3 0 RIC1 Bombinin PF05298.11 VBB33822.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Bombinin TPR_2 PF07719.17 VBB33822.1 - 0.68 10.2 3.1 1.4 9.2 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1644 PF07800.12 VBB33822.1 - 0.97 9.5 4.8 15 5.7 4.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Prok-RING_1 PF14446.6 VBB33822.1 - 1.3 9.0 15.2 8.8 6.3 0.4 3.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 ANAPC3 PF12895.7 VBB33822.1 - 1.8 8.9 6.2 4.1 7.7 0.3 4.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-LITAF-like PF10601.9 VBB33822.1 - 4.2 7.7 9.9 13 6.1 0.4 2.6 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-ANAPC11 PF12861.7 VBB33822.1 - 6 7.0 11.8 17 5.5 7.6 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_15 PF17032.5 VBB33822.1 - 8.4 7.2 13.5 2.1 9.2 2.7 3.6 4 0 0 4 4 4 0 zinc-ribbon family DUF953 PF06110.11 VBB33823.1 - 2.9e-34 117.2 0.2 3.5e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 VBB33823.1 - 0.00044 20.0 0.4 0.0031 17.3 0.4 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 VBB33823.1 - 0.042 14.3 0.0 0.064 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 VBB33823.1 - 0.045 13.7 0.2 0.2 11.6 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin SH3_2 PF07653.17 VBB33825.1 - 2.1e-20 72.2 0.0 7.4e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 VBB33825.1 - 1.3e-15 57.0 0.0 3e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 VBB33825.1 - 1.1e-08 34.6 0.1 0.0026 17.3 0.0 3.1 2 2 0 2 2 2 2 SH3 domain CoaE PF01121.20 VBB33826.1 - 3.1e-37 128.0 0.1 3.6e-37 127.8 0.1 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase RRM_1 PF00076.22 VBB33827.1 - 2.2e-36 123.5 0.1 1.7e-13 50.2 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB33827.1 - 0.004 17.0 0.0 2.9 7.8 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 VBB33827.1 - 0.016 15.0 0.2 4.7 7.0 0.0 3.3 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 VBB33827.1 - 0.024 14.7 0.5 12 6.1 0.1 4.4 4 1 0 4 4 4 0 Limkain b1 Phage_TAC_13 PF16459.5 VBB33827.1 - 0.04 14.4 0.0 0.51 10.8 0.0 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone, TAC Urm1 PF09138.11 VBB33828.1 - 1.8e-27 95.5 0.1 4e-27 94.4 0.0 1.5 2 0 0 2 2 2 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 VBB33828.1 - 6.6e-05 23.5 0.0 0.0001 22.9 0.0 1.4 1 0 0 1 1 1 1 ThiS family MIP PF00230.20 VBB33829.1 - 2.9e-36 125.3 11.3 3.6e-36 125.0 11.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein CDT1 PF08839.11 VBB33830.1 - 8.6e-39 133.6 0.2 8.6e-39 133.6 0.2 2.9 3 1 0 3 3 3 1 DNA replication factor CDT1 like CDT1_C PF16679.5 VBB33830.1 - 3.7e-08 33.7 5.5 6.7e-08 32.9 0.7 3.0 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain Peptidase_A22B PF04258.13 VBB33832.1 - 2e-24 86.6 0.1 1.4e-17 64.1 0.4 2.1 1 1 1 2 2 2 2 Signal peptide peptidase 7TM-7TMR_HD PF07698.11 VBB33832.1 - 0.03 14.1 1.4 0.043 13.6 1.4 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase WD40_3 PF15911.5 VBB33833.1 - 3.3e-19 68.6 0.1 8.6e-19 67.3 0.1 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 VBB33833.1 - 0.036 13.1 3.7 2.3 7.2 0.1 2.8 3 0 0 3 3 3 0 Coatomer WD associated region TPR_2 PF07719.17 VBB33833.1 - 0.27 11.4 8.9 13 6.2 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB33833.1 - 0.47 10.4 4.8 40 4.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat FF PF01846.19 VBB33835.1 - 1.7e-43 146.5 32.7 9.6e-12 44.9 0.4 4.3 4 0 0 4 4 4 4 FF domain DTW PF03942.15 VBB33835.1 - 0.013 15.2 1.0 0.16 11.6 0.1 2.4 2 0 0 2 2 2 0 DTW domain 7tm_1 PF00001.21 VBB33836.1 - 2.5e-19 69.6 0.1 2.8e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) S-methyl_trans PF02574.16 VBB33837.1 - 2.4e-50 171.9 0.0 2.9e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DHO_dh PF01180.21 VBB33837.1 - 0.063 12.5 0.1 0.12 11.5 0.1 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Pep_M12B_propep PF01562.19 VBB33838.1 - 1.4e-10 41.6 0.0 2.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M16_C PF05193.21 VBB33840.1 - 1.8e-28 99.8 0.0 3.2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 VBB33840.1 - 2.6e-24 85.9 0.0 4.1e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Med14 PF08638.11 VBB33842.1 - 0.056 12.9 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 VWA_2 PF13519.6 VBB33843.1 - 1.7e-16 60.8 0.0 2.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 VBB33843.1 - 0.00039 20.7 0.0 0.00071 19.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain bZIP_1 PF00170.21 VBB33844.1 - 6.1e-06 26.2 14.5 6.1e-06 26.2 14.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 VBB33844.1 - 0.00012 22.6 8.8 0.00027 21.4 8.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 VBB33844.1 - 0.0035 17.4 17.8 0.0035 17.4 17.8 2.3 2 1 1 3 3 3 2 Basic region leucine zipper GIT_CC PF16559.5 VBB33844.1 - 0.012 15.5 2.7 0.029 14.2 2.7 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2524 PF10732.9 VBB33844.1 - 0.11 12.8 5.2 0.27 11.6 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) GrpE PF01025.19 VBB33844.1 - 1.7 8.3 10.1 5.1 6.7 10.1 1.9 1 1 0 1 1 1 0 GrpE DivIC PF04977.15 VBB33844.1 - 2.2 8.1 9.0 2.1 8.2 6.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 VBB33844.1 - 8.6 5.6 8.0 55 3.0 7.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 VBB33845.1 - 9.7e-14 51.6 15.2 9.9e-05 23.1 1.0 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat WD40_like PF17005.5 VBB33845.1 - 0.058 12.7 0.0 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain EB PF01683.18 VBB33846.1 - 9.7e-28 96.2 90.6 9.8e-09 35.4 13.7 6.9 4 2 2 6 6 6 5 EB module HLH PF00010.26 VBB33847.1 - 9.9e-18 63.9 0.2 1.4e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain uDENN PF03456.18 VBB33848.1 - 0.0028 18.4 0.0 0.0036 18.0 0.0 1.1 1 0 0 1 1 1 1 uDENN domain uDENN PF03456.18 VBB33849.1 - 0.014 16.1 0.0 0.027 15.2 0.0 1.4 1 0 0 1 1 1 0 uDENN domain Tim17 PF02466.19 VBB33851.1 - 1.1e-10 41.9 6.9 3.1e-09 37.2 6.9 2.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CPBP PF02517.16 VBB33851.1 - 0.42 11.0 3.4 92 3.5 0.1 3.6 3 1 0 3 3 3 0 CPBP intramembrane metalloprotease M_domain PF12938.7 VBB33855.1 - 1.5e-10 41.3 11.6 1.9e-10 41.0 11.6 1.1 1 0 0 1 1 1 1 M domain of GW182 ABC_tran_CTD PF16326.5 VBB33855.1 - 0.017 15.4 3.9 0.24 11.7 0.5 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain PhnH PF05845.12 VBB33855.1 - 0.034 13.9 0.5 0.049 13.4 0.5 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) OmpH PF03938.14 VBB33855.1 - 0.071 13.4 6.4 0.12 12.7 6.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RXT2_N PF08595.11 VBB33855.1 - 0.085 12.9 0.3 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3422 PF11902.8 VBB33855.1 - 1.2 8.1 7.3 0.21 10.6 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3422) Prefoldin PF02996.17 VBB33857.1 - 1.3e-23 83.1 0.8 1.6e-23 82.9 0.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF3734 PF12536.8 VBB33857.1 - 0.029 14.7 0.2 0.095 13.0 0.1 1.7 2 0 0 2 2 2 0 Patatin phospholipase Prefoldin_2 PF01920.20 VBB33857.1 - 0.15 12.0 2.5 0.66 10.0 2.5 1.9 1 1 0 1 1 1 0 Prefoldin subunit RPEL PF02755.15 VBB33858.1 - 2.5e-15 55.6 8.4 2e-07 30.5 4.1 2.8 2 0 0 2 2 2 2 RPEL repeat RecG_wedge PF17191.4 VBB33858.1 - 0.013 15.1 0.3 0.027 14.1 0.3 1.5 1 0 0 1 1 1 0 RecG wedge domain UPF0020 PF01170.18 VBB33859.1 - 1.2e-11 44.7 0.0 7.6e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 VBB33859.1 - 1.8e-06 27.8 0.0 0.00065 19.5 0.0 2.2 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 VBB33859.1 - 0.00013 21.3 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_15 PF09445.10 VBB33859.1 - 0.0083 15.7 0.2 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 VBB33859.1 - 0.012 16.2 0.1 0.2 12.4 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.15 VBB33859.1 - 0.024 14.3 0.1 1.5 8.4 0.1 2.2 1 1 0 1 1 1 0 Conserved hypothetical protein 95 7TM_GPCR_Srab PF10292.9 VBB33860.1 - 4.6e-27 94.8 27.5 3.9e-26 91.7 27.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sre PF03125.18 VBB33860.1 - 2.2e-11 43.5 29.2 3.3e-11 42.9 29.2 1.3 1 0 0 1 1 1 1 C. elegans Sre G protein-coupled chemoreceptor 7TM_GPCR_Sra PF02117.16 VBB33860.1 - 0.00018 20.4 26.2 0.0041 16.0 6.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Sra zf-RING_2 PF13639.6 VBB33861.1 - 8.8e-08 32.4 6.5 1.4e-07 31.7 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 VBB33861.1 - 4.8e-05 23.2 4.7 0.00011 22.1 4.9 1.5 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 VBB33861.1 - 0.00019 21.0 2.7 0.0003 20.4 2.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 VBB33861.1 - 0.0002 21.1 7.6 0.00086 19.1 8.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB33861.1 - 0.00056 19.7 5.2 0.0011 18.8 5.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 VBB33861.1 - 0.0013 18.8 1.7 0.002 18.2 1.7 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 VBB33861.1 - 0.0026 17.6 6.6 0.033 14.0 7.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB33861.1 - 0.0087 16.1 2.2 0.014 15.5 2.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 VBB33861.1 - 0.062 13.6 11.5 0.45 10.8 11.3 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 VBB33861.1 - 0.093 12.6 9.5 2.1 8.2 10.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 C1_2 PF03107.16 VBB33861.1 - 0.1 13.0 2.1 9.2 6.7 0.2 2.3 2 0 0 2 2 2 0 C1 domain zf-RING_11 PF17123.5 VBB33861.1 - 0.12 12.2 5.1 0.096 12.5 1.7 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 VBB33861.1 - 0.15 12.1 6.9 0.41 10.7 5.9 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 VBB33861.1 - 0.71 9.7 6.6 3 7.7 6.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 VBB33861.1 - 1.2 9.3 5.7 2.7 8.2 5.7 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 VBB33861.1 - 2.6 8.4 7.9 7.1 7.0 7.9 1.8 1 1 0 1 1 1 0 RING-like domain PIP49_C PF12260.8 VBB33862.1 - 2.3e-30 105.6 1.7 3.8e-30 104.9 1.7 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 VBB33862.1 - 0.017 15.0 2.9 0.017 15.0 2.9 2.8 2 1 0 2 2 2 0 N-term cysteine-rich ER, FAM69 Ribosom_S12_S23 PF00164.25 VBB33863.1 - 1.1e-15 57.2 0.1 1.2e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 S-AdoMet_synt_C PF02773.16 VBB33864.1 - 5.3e-66 220.8 0.1 7.4e-65 217.1 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 VBB33864.1 - 2.2e-43 147.3 0.0 3.7e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 VBB33864.1 - 5e-41 139.4 1.5 8.2e-41 138.7 0.2 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amidase PF01425.21 VBB33865.1 - 6e-116 388.1 0.0 6.8e-116 387.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Thioredoxin PF00085.20 VBB33866.1 - 2e-05 24.5 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 VBB33866.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE LRR_8 PF13855.6 VBB33867.1 - 5.4e-34 115.8 74.0 8.3e-09 35.1 7.8 11.5 6 4 6 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 VBB33867.1 - 5.8e-28 96.5 74.0 1.5e-05 25.3 4.8 12.2 6 2 6 13 13 13 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 VBB33867.1 - 7.4e-07 28.9 64.8 3.8 8.4 0.2 16.7 16 2 0 16 16 16 2 Leucine Rich Repeat LRR_9 PF14580.6 VBB33867.1 - 5.1e-06 26.1 28.9 0.028 13.9 4.3 5.2 2 2 2 5 5 5 5 Leucine-rich repeat LRR_5 PF13306.6 VBB33867.1 - 6.2e-05 23.0 10.8 0.066 13.2 0.4 3.9 3 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 VBB33867.1 - 2 8.7 73.1 8.5 6.7 0.4 16.0 16 1 1 17 17 17 0 Leucine Rich repeat Metallophos PF00149.28 VBB33868.1 - 7e-38 131.2 0.3 9.3e-38 130.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Band_7 PF01145.25 VBB33870.1 - 1.2e-09 38.5 5.1 0.0001 22.4 2.0 2.3 1 1 1 2 2 2 2 SPFH domain / Band 7 family GP68 PF17469.2 VBB33870.1 - 0.043 14.2 0.2 0.11 13.0 0.2 1.7 1 0 0 1 1 1 0 Phage protein Gp68 DUF4279 PF14106.6 VBB33870.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF1712 PF08217.11 VBB33870.1 - 0.11 11.0 1.4 0.14 10.6 1.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) RhlB PF12300.8 VBB33873.1 - 0.14 12.3 3.6 0.19 11.9 3.6 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB AcetylCoA_hyd_C PF13336.6 VBB33874.1 - 4.1e-57 192.4 0.0 6.6e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 VBB33874.1 - 4.5e-13 49.6 0.0 9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain zf-CCCH_4 PF18044.1 VBB33875.1 - 7.1e-21 73.5 30.7 1.6e-07 31.0 0.6 4.6 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 VBB33875.1 - 2.9e-16 58.9 38.5 1.5e-05 24.8 4.0 5.2 6 0 0 6 6 6 4 Zinc finger domain zf-CCCH PF00642.24 VBB33875.1 - 2.1e-15 56.1 26.7 9.6e-06 25.4 0.4 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 VBB33875.1 - 1.2e-13 51.7 13.6 0.00032 21.4 0.1 4.5 3 1 1 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 VBB33875.1 - 1.3e-05 25.5 31.7 0.0055 17.1 2.0 4.9 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 VBB33875.1 - 0.0059 16.8 0.9 0.0059 16.8 0.9 3.6 2 1 0 3 3 3 2 Zinc-finger containing family PAT1 PF09770.9 VBB33876.1 - 6e-06 24.9 3.0 2.1e-05 23.0 1.7 2.3 2 1 0 2 2 2 1 Topoisomerase II-associated protein PAT1 SRP40_C PF05022.12 VBB33877.1 - 4.4e-23 81.9 7.0 4.4e-23 81.9 7.0 4.0 4 1 0 4 4 4 1 SRP40, C-terminal domain Ribosomal_L7Ae PF01248.26 VBB33878.1 - 2e-23 81.9 0.0 2.8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 VBB33878.1 - 0.014 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Peptidase_M13_N PF05649.13 VBB33879.1 - 1.1e-95 321.6 0.8 1.2e-95 321.4 0.8 1.0 1 0 0 1 1 1 1 Peptidase family M13 RhoGAP PF00620.27 VBB33881.1 - 1.9e-49 167.4 0.2 8.4e-49 165.3 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain ATP-synt_Eps PF04627.13 VBB33882.1 - 1.1e-19 70.1 0.2 1.3e-19 69.9 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Nop53 PF07767.11 VBB33883.1 - 0.006 16.0 7.0 0.0097 15.3 7.0 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3221 PF11518.8 VBB33883.1 - 0.021 15.2 1.9 0.043 14.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Nop25 PF09805.9 VBB33883.1 - 0.32 11.5 11.3 0.75 10.3 11.3 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) PBP_sp32 PF07222.12 VBB33883.1 - 0.43 10.0 3.1 0.61 9.5 3.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec62 PF03839.16 VBB33883.1 - 3.6 7.0 6.3 5 6.6 6.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3246 PF11596.8 VBB33883.1 - 5.3 6.4 11.7 0.3 10.5 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) GST_N_4 PF17172.4 VBB33885.1 - 1.4e-25 89.9 0.0 2.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 VBB33885.1 - 8.8e-08 32.5 0.0 1.4e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Aa_trans PF01490.18 VBB33886.1 - 1.6e-15 56.8 0.8 1.7e-15 56.7 0.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 VBB33886.1 - 6.8e-05 22.1 2.0 6.8e-05 22.1 2.0 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family VIT1 PF01988.19 VBB33886.1 - 0.57 10.0 5.1 0.68 9.8 5.1 1.0 1 0 0 1 1 1 0 VIT family Phage_holin_3_6 PF07332.11 VBB33886.1 - 2.2 8.3 6.4 3.4 7.7 6.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 VBB33886.1 - 2.7 6.6 4.1 3.1 6.4 4.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Myc_N PF01056.18 VBB33887.1 - 0.062 13.2 5.3 0.076 12.9 5.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Neur_chan_LBD PF02931.23 VBB33888.1 - 3.1e-49 167.4 0.6 3e-33 115.1 0.6 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB33888.1 - 8.9e-46 156.9 11.4 2.9e-37 129.0 7.1 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF1129 PF06570.11 VBB33888.1 - 0.26 10.7 1.8 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TRP PF06011.12 VBB33888.1 - 1.4 7.6 6.6 0.75 8.5 0.1 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel BTB PF00651.31 VBB33889.1 - 2.5e-12 47.0 0.1 2.9e-11 43.6 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 VBB33889.1 - 0.00044 20.3 0.7 2 8.5 0.1 3.6 3 1 1 4 4 4 2 BTB And C-terminal Kelch Globin PF00042.22 VBB33890.1 - 5.3e-15 55.9 1.1 7.5e-15 55.4 1.1 1.2 1 0 0 1 1 1 1 Globin Homeodomain PF00046.29 VBB33891.1 - 1.4e-21 76.0 6.3 2.5e-21 75.2 6.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB33891.1 - 0.00069 19.5 0.7 0.0017 18.2 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 VBB33891.1 - 0.0036 16.7 1.1 0.0079 15.6 1.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 VBB33891.1 - 0.022 14.6 0.4 0.056 13.3 0.4 1.7 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PPS_PS PF02006.16 VBB33892.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Sybindin PF04099.12 VBB33894.1 - 9.7e-49 165.0 0.0 1.2e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 VBB33894.1 - 2.3e-08 34.3 0.0 4.5e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Peptidase_A17 PF05380.13 VBB33895.1 - 1.8e-12 47.6 0.1 3.4e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Pao retrotransposon peptidase DUF1758 PF05585.12 VBB33895.1 - 0.0019 18.0 0.2 0.0094 15.7 0.0 1.9 1 1 1 2 2 2 1 Putative peptidase (DUF1758) AP4E_app_platf PF14807.6 VBB33895.1 - 0.077 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Pyr_redox_3 PF13738.6 VBB33896.1 - 8.2e-08 31.9 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 VBB33896.1 - 0.00011 21.5 0.0 0.00071 18.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 VBB33896.1 - 0.00012 21.4 0.0 0.091 12.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 VBB33896.1 - 0.0059 15.9 0.1 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 VBB33896.1 - 0.011 15.8 0.0 0.31 11.0 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FMO-like PF00743.19 VBB33896.1 - 0.012 14.1 0.0 0.09 11.2 0.0 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like SMN PF06003.12 VBB33897.1 - 0.002 17.5 2.8 0.0025 17.1 2.8 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) PEHE PF15275.6 VBB33897.1 - 0.19 12.4 9.5 0.16 12.6 6.5 2.1 2 0 0 2 2 2 0 PEHE domain Transmemb_17 PF09799.9 VBB33898.1 - 7.3e-19 68.3 8.7 7.8e-19 68.2 8.2 1.3 1 1 0 1 1 1 1 Predicted membrane protein Sec62 PF03839.16 VBB33898.1 - 1.6 8.2 3.0 2.3 7.6 3.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF5489 PF17592.2 VBB33898.1 - 8.3 7.0 9.3 8.9 6.9 0.8 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5489) DUF778 PF05608.12 VBB33899.1 - 3.8e-34 118.7 3.5 1.1e-21 78.0 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) ABC_tran PF00005.27 VBB33900.1 - 3.1e-05 24.5 0.0 8.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 VBB33900.1 - 0.016 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 VBB33900.1 - 0.027 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 VBB33900.1 - 0.041 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase KAP_NTPase PF07693.14 VBB33900.1 - 0.042 13.1 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 VBB33900.1 - 0.042 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 VBB33900.1 - 0.05 14.0 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 VBB33900.1 - 0.055 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 VBB33900.1 - 0.07 13.4 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 VBB33900.1 - 0.083 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 VBB33900.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 VBB33900.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 VBB33900.1 - 0.22 12.0 0.4 0.48 10.9 0.4 1.5 1 0 0 1 1 1 0 AAA domain PPI_Ypi1 PF07491.11 VBB33901.1 - 1e-19 70.1 4.3 2.1e-19 69.1 4.3 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor Ribosomal_L22 PF00237.19 VBB33902.1 - 5.6e-43 145.4 0.8 5.6e-43 145.4 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e NAC PF01849.18 VBB33903.1 - 2.5e-23 81.8 0.0 6.7e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 NAC domain PGA2 PF07543.12 VBB33903.1 - 3.5 7.6 10.6 1.8 8.6 2.9 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 MFS_1 PF07690.16 VBB33904.1 - 2.4e-31 108.9 31.3 9.4e-26 90.6 13.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily PIRT PF15099.6 VBB33904.1 - 4 7.0 5.4 1.9 8.1 0.6 2.5 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family CorA PF01544.18 VBB33905.1 - 1.8e-05 24.2 8.3 1.8e-05 24.2 8.3 2.9 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein Calc_CGRP_IAPP PF00214.19 VBB33905.1 - 0.015 15.7 1.7 0.015 15.7 1.7 3.5 4 1 0 4 4 4 0 Calcitonin / CGRP / IAPP family PMC2NT PF08066.12 VBB33905.1 - 5.1 7.9 9.1 0.6 10.8 1.0 3.5 3 1 0 3 3 3 0 PMC2NT (NUC016) domain TTR-52 PF01060.23 VBB33906.1 - 4.1e-16 59.5 0.0 5.1e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family bMG3 PF11974.8 VBB33906.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TTR-52 PF01060.23 VBB33907.1 - 1e-22 80.6 0.0 1.4e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family MGAT2 PF05060.14 VBB33908.1 - 4.5e-139 463.4 6.9 5.2e-139 463.2 6.9 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) DUF4293 PF14126.6 VBB33909.1 - 0.028 14.7 6.1 0.044 14.0 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) L_HMGIC_fpl PF10242.9 VBB33909.1 - 0.9 9.7 10.3 0.89 9.7 8.2 2.1 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 VBB33909.1 - 0.93 9.4 17.7 6.2 6.7 17.7 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like COG7 PF10191.9 VBB33911.1 - 1.1e-10 40.5 0.3 2.2e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) Glyco_hydro_57 PF03065.15 VBB33911.1 - 0.083 12.1 0.3 0.16 11.1 0.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 ETF_QO PF05187.13 VBB33913.1 - 1.4e-32 112.0 0.2 1.5e-32 111.8 0.2 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 VBB33913.1 - 0.0049 17.4 2.8 0.0075 16.8 2.8 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain TNFR_c6 PF00020.18 VBB33913.1 - 0.01 16.3 3.3 0.75 10.3 0.1 2.2 2 0 0 2 2 2 2 TNFR/NGFR cysteine-rich region Fer4_2 PF12797.7 VBB33913.1 - 0.065 13.4 0.6 0.065 13.4 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 VBB33913.1 - 3.3 8.5 6.9 1.5 9.5 2.3 2.2 2 1 0 2 2 2 0 4Fe-4S binding domain COX6A PF02046.15 VBB33916.1 - 7.5e-10 39.3 0.8 1.1e-09 38.7 0.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Phytochelatin PF05023.14 VBB33918.1 - 1.1e-87 292.8 0.0 2.2e-87 291.8 0.0 1.6 1 0 0 1 1 1 1 Phytochelatin synthase START PF01852.19 VBB33918.1 - 5.2e-14 52.2 0.0 7.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 START domain CLASP_N PF12348.8 VBB33920.1 - 5.5e-11 42.5 0.1 7.8e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 VBB33920.1 - 2.2e-08 33.6 1.5 0.00035 20.6 0.0 4.1 5 0 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.7 VBB33920.1 - 1.1e-05 25.9 0.1 0.00017 22.1 0.0 2.4 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 VBB33920.1 - 3.2e-05 24.2 0.1 0.0016 18.8 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 VBB33920.1 - 0.00016 22.1 0.0 0.0054 17.2 0.0 2.7 2 0 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 VBB33920.1 - 0.00019 20.2 0.1 0.00036 19.2 0.1 1.4 1 1 1 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 VBB33920.1 - 0.014 15.5 0.9 0.05 13.7 0.3 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 VBB33920.1 - 0.026 14.1 0.1 0.55 9.8 0.0 2.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 VBB33920.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Neur_chan_LBD PF02931.23 VBB33921.1 - 1.3e-17 64.0 0.1 1.5e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Glyco_transf_7C PF02709.14 VBB33922.1 - 1.7e-27 94.8 0.4 3.1e-27 94.0 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 VBB33922.1 - 4.1e-08 32.9 0.8 7.1e-08 32.2 0.8 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 VBB33922.1 - 0.16 11.4 1.2 0.65 9.4 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF4131 PF13567.6 VBB33923.1 - 3.2 7.4 11.5 0.42 10.3 6.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF485 PF04341.12 VBB33923.1 - 4.3 7.4 10.9 63 3.6 9.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 CH PF00307.31 VBB33926.1 - 4.1e-22 78.4 0.0 4.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 VBB33926.1 - 2.3e-06 27.3 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Tropomyosin_1 PF12718.7 VBB33927.1 - 4e-08 33.5 12.6 4.1e-08 33.5 12.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 VBB33927.1 - 4e-06 26.4 12.7 4.6e-06 26.2 12.7 1.0 1 0 0 1 1 1 1 Tropomyosin CLZ PF16526.5 VBB33927.1 - 8.7e-05 22.8 9.0 0.00011 22.5 9.0 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HrpB7 PF09486.10 VBB33927.1 - 0.0014 19.0 9.5 0.0015 18.9 9.5 1.0 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Tektin PF03148.14 VBB33927.1 - 0.0052 15.6 7.8 0.0056 15.5 7.8 1.0 1 0 0 1 1 1 1 Tektin family Laminin_II PF06009.12 VBB33927.1 - 0.0095 16.0 6.3 0.012 15.7 6.3 1.0 1 0 0 1 1 1 1 Laminin Domain II GAS PF13851.6 VBB33927.1 - 0.013 14.8 10.7 0.015 14.6 10.7 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 VBB33927.1 - 0.017 15.2 13.4 0.019 15.0 13.4 1.0 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 VBB33927.1 - 0.021 15.1 6.6 0.024 14.9 6.6 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 YkyA PF10368.9 VBB33927.1 - 0.026 14.2 11.7 0.03 14.0 11.7 1.0 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF1664 PF07889.12 VBB33927.1 - 0.03 14.3 5.4 0.034 14.2 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 VBB33927.1 - 0.04 13.3 12.1 0.052 13.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) WXG100 PF06013.12 VBB33927.1 - 0.049 13.9 1.3 0.049 13.9 1.3 1.9 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DLP_helical PF18709.1 VBB33927.1 - 0.063 12.5 5.8 0.062 12.5 5.8 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain Lebercilin PF15619.6 VBB33927.1 - 0.093 12.4 12.3 0.27 10.9 12.6 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.14 VBB33927.1 - 0.11 12.3 7.5 0.12 12.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 VBB33927.1 - 0.12 12.3 12.4 0.33 10.9 3.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF3584 PF12128.8 VBB33927.1 - 0.14 9.7 9.6 0.16 9.5 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3958 PF13125.6 VBB33927.1 - 0.16 12.2 9.8 0.096 12.9 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Exonuc_VII_L PF02601.15 VBB33927.1 - 0.19 11.3 3.7 0.2 11.2 3.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 VBB33927.1 - 0.19 10.9 9.5 0.23 10.6 9.5 1.0 1 0 0 1 1 1 0 Tail length tape measure protein Nup88 PF10168.9 VBB33927.1 - 0.21 9.4 5.8 0.24 9.2 5.8 1.0 1 0 0 1 1 1 0 Nuclear pore component CCDC-167 PF15188.6 VBB33927.1 - 0.28 11.6 8.3 0.69 10.3 8.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 BEX PF04538.12 VBB33927.1 - 0.39 11.3 8.5 0.66 10.6 8.4 1.6 1 1 0 1 1 1 0 Brain expressed X-linked like family Atg14 PF10186.9 VBB33927.1 - 0.56 9.2 5.6 0.62 9.1 5.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 VBB33927.1 - 0.71 10.2 5.4 0.96 9.8 5.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 VBB33927.1 - 1 8.5 5.6 1.1 8.5 5.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein SNARE PF05739.19 VBB33927.1 - 1.7 8.7 5.1 3.3 7.8 0.5 2.3 1 1 2 3 3 3 0 SNARE domain DUF2951 PF11166.8 VBB33927.1 - 1.9 8.8 9.5 2.2 8.5 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) XhlA PF10779.9 VBB33927.1 - 2.3 8.5 10.8 17 5.7 10.8 2.0 1 1 0 1 1 1 0 Haemolysin XhlA DUF5446 PF17522.2 VBB33927.1 - 2.5 8.3 9.6 4.4 7.5 1.7 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5446) His_Phos_1 PF00300.22 VBB33928.1 - 6e-39 133.8 0.0 7.3e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 VBB33930.1 - 2.7e-36 125.2 22.1 3.4e-36 124.9 22.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4992 PF16383.5 VBB33930.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function Globin PF00042.22 VBB33931.1 - 2.2e-05 25.0 0.0 3.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Globin DUF2660 PF10859.8 VBB33931.1 - 0.0023 18.4 1.1 0.5 10.9 0.1 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF2660) CAP18_C PF12153.8 VBB33931.1 - 0.025 14.4 3.0 0.39 10.6 0.9 2.6 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) Protoglobin PF11563.8 VBB33931.1 - 0.047 13.6 0.0 0.076 12.9 0.0 1.3 1 1 0 1 1 1 0 Protoglobin FEZ PF07763.13 VBB33932.1 - 0.0089 15.8 1.3 0.012 15.4 1.3 1.2 1 0 0 1 1 1 1 FEZ-like protein EF-hand_7 PF13499.6 VBB33932.1 - 0.032 14.7 1.4 0.068 13.6 0.9 1.8 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 VBB33932.1 - 0.06 13.3 0.6 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 VBB33932.1 - 0.093 12.3 0.1 0.29 10.8 0.1 1.9 1 0 0 1 1 1 0 EF hand DUF1759 PF03564.15 VBB33932.1 - 0.11 12.5 0.9 0.7 9.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Jiraiya PF15038.6 VBB33932.1 - 0.18 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Jiraiya Ribosomal_S13 PF00416.22 VBB33932.1 - 0.57 10.6 4.1 6.3 7.2 0.1 2.7 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Suppressor_APC PF11414.8 VBB33933.1 - 2.4e-07 30.7 1.2 7e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein DUF2461 PF09365.10 VBB33933.1 - 0.0037 17.2 0.1 0.0066 16.4 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Lem_TRP PF08262.11 VBB33933.1 - 0.29 11.2 0.6 0.52 10.4 0.6 1.4 1 0 0 1 1 1 0 Leucophaea maderae tachykinin-related peptide adh_short PF00106.25 VBB33934.1 - 7.9e-34 116.8 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB33934.1 - 5e-25 88.4 0.0 6.5e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 VBB33934.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_30 PF02055.16 VBB33934.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain HHH PF00633.23 VBB33934.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif MFP2b PF12150.8 VBB33935.1 - 1.9e-20 73.5 0.0 3.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic motility protein Ank_5 PF13857.6 VBB33935.1 - 1.7e-13 50.5 1.5 1.3e-06 28.5 0.3 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB33935.1 - 2.9e-12 45.6 1.9 5.5e-05 23.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 VBB33935.1 - 9.2e-12 45.4 4.1 1.1e-06 29.1 1.9 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB33935.1 - 7.4e-11 42.4 1.0 0.0053 17.3 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 VBB33935.1 - 1.4e-10 41.1 2.2 0.094 13.2 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Cyclin_C_2 PF16899.5 VBB33936.1 - 0.014 15.7 0.1 0.052 13.9 0.0 1.8 2 0 0 2 2 2 0 Cyclin C-terminal domain OLF PF02191.16 VBB33937.1 - 1.5e-20 73.8 0.5 2e-20 73.4 0.5 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_1 PF00001.21 VBB33938.1 - 0.00064 19.1 12.5 0.00084 18.7 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Inhibitor_I68 PF10468.9 VBB33938.1 - 0.057 13.8 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 RseC_MucC PF04246.12 VBB33938.1 - 0.1 12.6 2.0 0.44 10.5 0.1 2.5 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC 7TM_GPCR_Srh PF10318.9 VBB33938.1 - 0.5 9.3 17.8 1.7 7.6 17.8 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh GDPD PF03009.17 VBB33939.1 - 5.2e-33 114.9 0.0 9.4e-33 114.0 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 VBB33939.1 - 0.046 14.2 0.2 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UPF0175 PF03683.13 VBB33939.1 - 0.047 13.4 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) F-box-like PF12937.7 VBB33940.1 - 1.5e-13 50.4 1.8 4e-13 49.0 1.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB33940.1 - 1.8e-08 34.1 2.2 2.9e-08 33.4 0.4 2.1 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 VBB33940.1 - 2.6e-06 27.0 1.3 0.024 14.7 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 VBB33940.1 - 3.8e-06 27.1 2.0 0.2 12.1 0.1 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 VBB33940.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 F-box LRR_1 PF00560.33 VBB33940.1 - 0.013 15.9 10.0 0.52 11.1 0.1 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat PA26 PF04636.13 VBB33944.1 - 7.8e-79 265.7 6.9 1.6e-78 264.6 6.9 1.4 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF3573 PF12097.8 VBB33944.1 - 0.12 11.1 0.7 0.2 10.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Hexokinase_2 PF03727.16 VBB33946.1 - 5e-83 278.2 0.0 6.9e-83 277.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 VBB33946.1 - 7.8e-71 238.1 0.0 1.1e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase GRAM PF02893.20 VBB33946.1 - 0.056 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 GRAM domain BET PF17035.5 VBB33946.1 - 0.16 12.2 0.4 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation SLC35F PF06027.12 VBB33947.1 - 8.7e-33 114.1 15.2 1.2e-32 113.6 15.2 1.2 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 VBB33947.1 - 0.00072 18.8 8.5 0.00093 18.5 8.5 1.1 1 0 0 1 1 1 1 UAA transporter family ICMT PF04140.14 VBB33947.1 - 0.1 13.0 2.0 0.17 12.3 2.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.20 VBB33947.1 - 0.11 12.7 13.5 0.14 12.4 13.5 1.1 1 0 0 1 1 1 0 EamA-like transporter family Det1 PF09737.9 VBB33948.1 - 7.8e-70 236.0 2.0 1.8e-67 228.3 2.0 2.1 1 1 0 1 1 1 1 De-etiolated protein 1 Det1 Ndufs5 PF10200.9 VBB33949.1 - 1.2e-10 41.5 1.8 1.3e-08 34.9 0.3 2.1 2 0 0 2 2 2 2 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 VBB33949.1 - 0.092 12.8 1.7 0.16 12.0 1.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 VBB33949.1 - 0.69 10.2 6.8 1.8 8.9 6.7 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Collagen PF01391.18 VBB33951.1 - 2e-10 40.3 25.8 2.5e-10 40.0 25.8 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB33952.1 - 5.7e-09 35.6 30.7 1.1e-08 34.7 30.7 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB33953.1 - 2.6e-17 62.3 64.4 3.3e-10 39.5 33.1 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SUIM_assoc PF16619.5 VBB33954.1 - 0.043 13.9 2.9 0.082 13.0 2.9 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WBP-1 PF11669.8 VBB33955.1 - 0.0097 16.5 0.1 0.018 15.7 0.1 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 Rab5ip PF07019.12 VBB33955.1 - 0.029 15.0 0.1 0.037 14.6 0.1 1.2 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) OAD_gamma PF04277.13 VBB33955.1 - 0.051 14.2 0.1 0.074 13.6 0.1 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TRAPPC9-Trs120 PF08626.11 VBB33958.1 - 2.6e-21 74.8 0.2 4e-10 37.8 0.0 2.9 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC-Trs85 PF12739.7 VBB33958.1 - 0.0074 15.3 2.3 0.016 14.2 2.2 1.7 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Nop PF01798.18 VBB33959.1 - 1.2e-84 283.3 0.0 1.2e-84 283.3 0.0 2.1 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 VBB33959.1 - 1.9e-20 73.0 0.0 8.2e-20 71.0 0.0 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain AA_permease_2 PF13520.6 VBB33960.1 - 0.011 14.6 4.0 0.014 14.2 4.0 1.2 1 0 0 1 1 1 0 Amino acid permease DUF2298 PF10060.9 VBB33960.1 - 0.011 14.5 0.2 0.013 14.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Exosortase_EpsH PF09721.10 VBB33960.1 - 0.037 13.6 2.9 0.047 13.2 2.9 1.1 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) Wzy_C PF04932.15 VBB33960.1 - 0.065 12.9 0.6 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 O-Antigen ligase DUF5565 PF17720.1 VBB33960.1 - 0.089 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) ABC2_membrane_5 PF13346.6 VBB33960.1 - 0.9 9.1 12.0 0.098 12.2 5.0 2.2 1 1 0 2 2 2 0 ABC-2 family transporter protein Ni_hydr_CYTB PF01292.20 VBB33960.1 - 1 8.9 4.2 0.51 9.9 1.7 1.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4173 PF13777.6 VBB33960.1 - 1.5 8.2 8.1 0.16 11.3 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) Colicin_im PF03857.13 VBB33960.1 - 1.7 8.6 9.0 0.45 10.5 4.8 2.1 1 1 1 2 2 2 0 Colicin immunity protein Glyco_hydro_38N PF01074.22 VBB33961.1 - 2.5e-71 240.4 5.8 2.9e-71 240.2 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_18 PF00704.28 VBB33962.1 - 7.1e-14 52.3 0.0 8e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 VBB33963.1 - 8.2e-13 48.3 4.5 1.2e-12 47.8 4.5 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain BNIP2 PF12496.8 VBB33963.1 - 2 8.9 6.6 3 8.3 6.6 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 MCLC PF05934.11 VBB33963.1 - 4.2 6.0 5.6 5 5.7 5.6 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Ank_2 PF12796.7 VBB33964.1 - 1.1e-15 58.0 0.1 4.2e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB33964.1 - 6.1e-11 42.6 0.0 7.4e-07 29.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB33964.1 - 7.1e-09 35.8 0.1 5.1e-07 29.9 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) SAM_2 PF07647.17 VBB33964.1 - 2.4e-08 33.9 0.6 3.1e-07 30.4 0.1 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 VBB33964.1 - 2.6e-08 33.5 0.4 5.2e-05 23.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat SAM_1 PF00536.30 VBB33964.1 - 3.2e-08 33.9 0.0 9.4e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 VBB33964.1 - 1.4e-06 28.5 0.1 0.0091 16.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat IFT81_CH PF18383.1 VBB33965.1 - 1.3e-08 35.1 0.1 1.3e-08 35.1 0.1 4.5 3 2 1 5 5 5 1 Intraflagellar transport 81 calponin homology domain MbeD_MobD PF04899.12 VBB33965.1 - 0.0053 16.8 9.4 1.7 8.8 0.0 5.4 5 1 0 5 5 5 2 MbeD/MobD like Phage-MuB_C PF09077.11 VBB33965.1 - 0.063 13.2 0.3 0.42 10.5 0.1 2.5 2 0 0 2 2 2 0 Mu B transposition protein, C terminal FUSC PF04632.12 VBB33965.1 - 0.3 9.5 2.9 0.24 9.9 0.5 2.0 1 1 2 3 3 3 0 Fusaric acid resistance protein family Rootletin PF15035.6 VBB33965.1 - 1.4 8.9 56.6 2.9e+02 1.3 25.5 4.2 2 2 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Thioredoxin_8 PF13905.6 VBB33966.1 - 1.6e-18 66.8 0.0 1.9e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 VBB33966.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin PF00085.20 VBB33966.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Strumpellin PF10266.9 VBB33968.1 - 1.9e-199 665.0 6.8 2.1e-199 664.9 6.8 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin KAR9 PF08580.10 VBB33968.1 - 0.0079 14.8 0.5 0.012 14.2 0.5 1.2 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Zip PF02535.22 VBB33969.1 - 3.1e-10 39.8 2.7 3.4e-10 39.7 2.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ebp2 PF05890.12 VBB33970.1 - 4.6e-64 216.6 32.9 5.2e-64 216.4 32.9 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DASH_Dam1 PF08653.10 VBB33970.1 - 0.12 12.2 0.2 4.5 7.1 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Trans_reg_C PF00486.28 VBB33970.1 - 0.28 11.3 4.3 1.4 9.1 0.1 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal tRNA_m1G_MT PF01746.21 VBB33971.1 - 0.011 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase DUF2192 PF09958.9 VBB33971.1 - 0.042 13.4 0.5 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2192) DUF563 PF04577.14 VBB33973.1 - 5.6e-07 29.9 0.0 8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) EF-hand_1 PF00036.32 VBB33974.1 - 1.7e-14 52.2 4.6 1.8e-07 30.2 1.9 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 VBB33974.1 - 1.9e-12 46.0 2.0 2.7e-07 30.0 0.9 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 VBB33974.1 - 2.1e-11 44.1 4.8 4.5e-09 36.6 2.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB33974.1 - 4.8e-10 38.5 1.7 0.00016 21.0 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 VBB33974.1 - 3.6e-07 29.9 2.1 0.01 15.6 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB33974.1 - 6.3e-05 23.3 0.3 6.3e-05 23.3 0.3 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 VBB33974.1 - 0.00077 19.4 2.0 0.27 11.2 1.7 2.2 1 1 1 2 2 2 2 Caleosin related protein DUF188 PF02639.14 VBB33974.1 - 0.079 12.6 0.4 0.17 11.5 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Uteroglobin PF01099.17 VBB33974.1 - 3.8 7.9 5.5 6.3 7.2 0.8 2.3 2 0 0 2 2 2 0 Uteroglobin family FKBP_N PF01346.18 VBB33974.1 - 7.6 7.6 8.2 0.85 10.6 2.7 2.1 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Neur_chan_LBD PF02931.23 VBB33975.1 - 6e-63 212.2 1.5 2e-55 187.6 0.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB33975.1 - 1.3e-13 51.5 3.8 1.9e-13 51.0 3.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SpoIIIAC PF06686.11 VBB33975.1 - 0.012 15.7 1.8 0.02 15.0 1.8 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Mito_carr PF00153.27 VBB33976.1 - 2e-49 165.4 0.2 4.4e-20 71.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 VBB33976.1 - 0.0013 18.0 0.0 0.092 11.9 0.0 2.4 2 1 0 2 2 2 2 Gammaproteobacterial serine protease MH1 PF03165.16 VBB33978.1 - 3.8e-38 129.9 1.9 6.5e-38 129.1 0.6 1.8 2 0 0 2 2 2 1 MH1 domain PSD2 PF07624.11 VBB33978.1 - 0.0024 17.6 0.6 0.0089 15.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1585) ACC_central PF08326.12 VBB33978.1 - 0.012 13.8 0.0 0.016 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF5371 PF17341.2 VBB33978.1 - 0.089 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5371) DDHD PF02862.17 VBB33979.1 - 0.034 14.3 5.2 0.039 14.1 5.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 VBB33979.1 - 0.055 12.8 5.2 0.077 12.3 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 VBB33979.1 - 0.057 11.3 9.4 0.064 11.2 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 VBB33979.1 - 0.06 13.3 17.4 0.07 13.1 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RP-C_C PF11800.8 VBB33979.1 - 0.37 10.9 8.4 0.43 10.6 8.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Adaptin_binding PF10199.9 VBB33979.1 - 0.45 11.1 16.2 3.8 8.2 13.0 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Androgen_recep PF02166.16 VBB33979.1 - 1.2 7.9 15.7 1.6 7.5 15.7 1.1 1 0 0 1 1 1 0 Androgen receptor ALMT PF11744.8 VBB33979.1 - 1.3 7.8 13.8 1.5 7.5 13.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DivIC PF04977.15 VBB33979.1 - 1.6 8.6 15.0 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator Neur_chan_memb PF02932.16 VBB33979.1 - 3.2 7.8 8.5 4 7.4 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 VBB33979.1 - 4.9 5.8 10.9 5.7 5.6 10.9 1.1 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 VBB33979.1 - 4.9 7.0 5.7 7 6.5 5.7 1.4 1 0 0 1 1 1 0 N-glycosylation protein TPR_12 PF13424.6 VBB33980.1 - 3.7e-09 36.8 0.7 5.8e-06 26.5 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 VBB33980.1 - 4.5e-08 32.7 6.1 0.15 12.0 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 VBB33980.1 - 9e-05 22.3 5.3 0.03 14.4 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 VBB33980.1 - 0.018 15.2 5.3 3.4 8.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 VBB33980.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.4 1 1 0 1 1 1 0 MalT-like TPR region TPR_1 PF00515.28 VBB33980.1 - 2.1 8.3 6.2 19 5.3 0.5 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat RHINO PF15319.6 VBB33982.1 - 0.32 11.0 3.2 0.47 10.4 3.2 1.3 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein DEAD_2 PF06733.15 VBB33983.1 - 2.1e-48 164.3 4.2 4.3e-48 163.2 4.2 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 VBB33983.1 - 1.8e-06 28.1 1.3 2.1e-05 24.6 0.6 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 VBB33983.1 - 3.3e-06 27.0 1.9 0.00013 21.8 0.2 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase HBB PF06777.11 VBB33983.1 - 0.0003 20.5 0.2 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 Helical and beta-bridge domain DUF2075 PF09848.9 VBB33983.1 - 0.0016 17.8 0.5 0.07 12.4 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 VBB33983.1 - 0.03 14.6 0.8 4.3 7.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 VBB33983.1 - 0.072 12.5 0.5 0.79 9.1 0.1 2.5 2 1 1 3 3 3 0 PhoH-like protein Y_phosphatase PF00102.27 VBB33984.1 - 0.012 15.2 0.9 0.014 14.9 0.9 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pex14_N PF04695.13 VBB33984.1 - 4.2 8.0 8.5 8.2 7.1 8.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 7tm_1 PF00001.21 VBB33987.1 - 1.1e-41 142.9 8.0 1.1e-41 142.9 8.0 2.1 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB33987.1 - 8.7e-08 31.8 8.0 1.4e-07 31.2 8.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 VBB33987.1 - 0.00011 21.9 14.4 0.00018 21.2 13.6 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 VBB33987.1 - 0.00028 20.5 11.9 0.00053 19.6 11.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srw PF10324.9 VBB33987.1 - 0.00058 19.2 9.0 0.0013 18.1 8.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw G-alpha PF00503.20 VBB33988.1 - 1.6e-107 359.7 0.9 2e-107 359.4 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB33988.1 - 4.9e-18 65.2 0.6 2.6e-13 49.8 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB33988.1 - 2.9e-06 26.8 3.8 0.00026 20.4 0.3 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 VBB33988.1 - 4.9e-05 23.5 0.7 0.097 12.9 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 VBB33988.1 - 0.016 15.2 0.1 0.75 9.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 VBB33988.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 VBB33988.1 - 0.065 12.8 0.5 7.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 VBB33988.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NMT1_3 PF16868.5 VBB33988.1 - 0.18 11.2 0.1 0.34 10.3 0.1 1.4 1 0 0 1 1 1 0 NMT1-like family C9orf72-like PF15019.6 VBB33989.1 - 3.4e-12 46.5 0.0 5.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 C9orf72-like protein family FAM222A PF15258.6 VBB33989.1 - 0.0099 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein family of FAM222A NOC3p PF07540.11 VBB33989.1 - 0.14 12.6 0.0 0.52 10.8 0.0 1.9 1 0 0 1 1 1 0 Nucleolar complex-associated protein Y_phosphatase PF00102.27 VBB33990.1 - 8.9e-61 205.4 0.8 1.1e-60 205.1 0.8 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB33990.1 - 3.1e-05 23.8 0.1 7.3e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB33990.1 - 3.7e-05 23.8 0.0 5.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB33990.1 - 0.073 13.2 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate P4Ha_N PF08336.11 VBB33991.1 - 1.4e-34 119.0 1.0 3.4e-34 117.7 1.0 1.7 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 VBB33991.1 - 7.8e-09 36.3 0.0 2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 VBB33991.1 - 0.00021 21.2 4.0 0.0026 17.8 0.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB33991.1 - 0.0066 16.6 1.3 0.14 12.4 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 VBB33991.1 - 0.0082 16.2 0.3 0.022 14.8 0.3 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 VBB33991.1 - 0.015 14.8 0.2 0.027 14.0 0.2 1.4 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 VBB33991.1 - 0.022 15.4 0.1 0.07 13.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB33991.1 - 0.06 13.9 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DM PF00751.18 VBB33992.1 - 4.5e-18 64.9 14.7 4.5e-18 64.9 14.7 1.8 2 0 0 2 2 2 1 DM DNA binding domain Macoilin PF09726.9 VBB33992.1 - 0.57 8.7 5.5 0.74 8.3 5.5 1.1 1 0 0 1 1 1 0 Macoilin family Myotub-related PF06602.14 VBB33994.1 - 0.071 12.0 0.3 0.077 11.9 0.3 1.0 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glyco_hydro_47 PF01532.20 VBB33995.1 - 5.4e-36 124.5 0.1 1.2e-35 123.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 TTR-52 PF01060.23 VBB33998.1 - 5.8e-29 100.6 0.0 7.4e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Transthyretin-like family DUF4061 PF13270.6 VBB33999.1 - 5.4e-05 23.4 2.2 9.4e-05 22.7 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) Ion_trans PF00520.31 VBB34000.1 - 1.7e-86 289.5 25.1 6.9e-58 195.8 22.5 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 VBB34000.1 - 7.8e-07 28.1 20.1 0.0016 17.2 17.4 3.3 2 1 0 2 2 2 2 Polycystin cation channel PBP1_TM PF14812.6 VBB34000.1 - 0.0023 18.2 0.7 0.0023 18.2 0.7 3.1 3 1 1 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 VBB34000.1 - 0.06 13.0 9.1 1.1 8.9 4.0 2.5 2 0 0 2 2 2 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 VBB34000.1 - 0.12 12.6 13.1 14 5.8 12.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Conotoxin PF02950.17 VBB34000.1 - 0.17 12.9 5.9 4.6 8.3 4.5 3.4 3 0 0 3 3 3 0 Conotoxin zf-C2H2 PF00096.26 VBB34003.1 - 0.00037 20.8 1.3 0.00037 20.8 1.3 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 VBB34003.1 - 0.0017 18.4 1.4 0.24 11.5 0.1 2.6 2 0 0 2 2 2 1 Zinc ribbon domain Baculo_PEP_C PF04513.12 VBB34003.1 - 0.0039 17.2 0.9 0.016 15.2 0.4 2.0 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-ribbon_3 PF13248.6 VBB34003.1 - 0.016 14.6 2.4 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 VBB34003.1 - 0.042 14.7 1.0 0.042 14.7 1.0 2.7 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 VBB34003.1 - 0.065 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 VBB34003.1 - 0.071 13.1 3.3 0.12 12.4 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.7 VBB34003.1 - 0.089 12.8 2.6 0.32 11.0 2.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon Mut7-C PF01927.16 VBB34003.1 - 0.14 12.3 0.1 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Mut7-C RNAse domain Laminin_II PF06009.12 VBB34003.1 - 0.15 12.1 0.9 5.7 7.0 0.1 2.4 1 1 1 2 2 2 0 Laminin Domain II zf-C2H2_jaz PF12171.8 VBB34003.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 VBB34003.1 - 0.19 11.3 1.7 2.4 7.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 VBB34003.1 - 0.24 11.4 1.3 7.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 VBB34003.1 - 0.3 10.9 4.2 9.1 6.2 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 VBB34003.1 - 0.52 10.1 0.1 0.52 10.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 VBB34003.1 - 0.85 9.8 4.4 7.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2_11 PF16622.5 VBB34003.1 - 1.1 9.1 5.3 0.69 9.7 0.6 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Pkinase PF00069.25 VBB34005.1 - 2.5e-69 233.6 0.0 3e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34005.1 - 5.6e-45 153.7 0.0 6.9e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB34005.1 - 6.5e-05 22.4 0.0 0.00052 19.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 VBB34005.1 - 0.00056 19.0 0.0 0.00094 18.2 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 VBB34005.1 - 0.031 13.9 0.6 0.11 12.1 0.0 2.1 3 0 0 3 3 3 0 RIO1 family BTB PF00651.31 VBB34006.1 - 7.1e-17 61.6 0.1 4.7e-09 36.5 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain Pox_MCEL PF03291.16 VBB34007.1 - 1.5e-88 297.1 0.0 1.8e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 VBB34007.1 - 4e-13 49.9 0.0 8.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 VBB34007.1 - 3.9e-09 37.0 0.0 9.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 VBB34007.1 - 1.6e-06 28.0 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB34007.1 - 6.2e-06 26.9 0.0 1.9e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 VBB34007.1 - 7.2e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 VBB34007.1 - 0.00036 20.7 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.17 VBB34007.1 - 0.0054 15.9 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 VBB34007.1 - 0.016 14.7 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 VBB34007.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Lipocalin_3 PF12702.7 VBB34007.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like fn3 PF00041.21 VBB34008.1 - 2.5e-47 159.2 11.2 1.1e-12 48.1 0.5 5.2 5 0 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 VBB34008.1 - 9.9e-10 38.9 13.0 0.00064 20.2 1.2 5.7 3 3 2 5 5 5 3 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 VBB34008.1 - 0.0041 17.0 0.1 15 5.6 0.0 4.8 4 2 0 4 4 4 1 Fibronectin-III type domain Interfer-bind PF09294.10 VBB34008.1 - 0.0043 17.4 0.0 3.8 7.9 0.0 3.2 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III DUF1654 PF07867.11 VBB34008.1 - 0.12 12.1 1.1 0.73 9.6 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1654) DUF4912 PF16258.5 VBB34008.1 - 1 9.6 4.1 16 5.7 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4912) ANAPC4_WD40 PF12894.7 VBB34010.1 - 0.012 15.9 0.1 6.4 7.2 0.0 4.7 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SUKH-4 PF14435.6 VBB34010.1 - 0.097 12.7 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 SUKH-4 immunity protein EMP24_GP25L PF01105.24 VBB34010.1 - 0.15 12.0 0.3 1.7 8.5 0.1 2.1 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FAD-oxidase_C PF02913.19 VBB34011.1 - 5.1e-53 180.3 0.0 6.8e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 VBB34011.1 - 2e-30 105.3 0.1 3.9e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain PIRT PF15099.6 VBB34012.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Transposase_24 PF03004.14 VBB34012.1 - 0.035 14.2 1.0 0.087 12.9 0.6 1.7 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Herpes_UL51 PF04540.13 VBB34012.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL51 protein PBP_N PF17093.5 VBB34013.1 - 0.019 15.2 0.6 0.025 14.8 0.6 1.1 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF4207 PF13904.6 VBB34014.1 - 0.59 9.8 29.4 0.78 9.4 7.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) Sterol-sensing PF12349.8 VBB34015.1 - 0.00037 20.4 2.1 0.00078 19.3 2.1 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation PBP1_TM PF14812.6 VBB34015.1 - 0.69 10.3 4.6 0.16 12.4 1.3 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Neur_chan_memb PF02932.16 VBB34017.1 - 2.1e-61 208.1 2.2 1.6e-29 103.7 0.0 2.7 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region UPF0640 PF15114.6 VBB34017.1 - 0.0037 17.0 2.0 1.1 9.1 0.4 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0640 DUF4396 PF14342.6 VBB34017.1 - 0.01 16.2 0.5 4.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) DUF1634 PF07843.11 VBB34017.1 - 0.34 11.0 9.1 3.3 7.9 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) Sugar_tr PF00083.24 VBB34019.1 - 1e-27 97.2 19.2 3.6e-27 95.3 19.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB34019.1 - 6.7e-20 71.3 32.2 5.7e-13 48.5 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily S8_pro-domain PF16470.5 VBB34020.1 - 7e-06 26.7 0.1 6.5e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase S8 pro-domain Trypsin PF00089.26 VBB34021.1 - 4.5e-25 88.8 0.0 2.4e-24 86.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 VBB34021.1 - 1.4e-09 38.0 0.0 4.3e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 VBB34021.1 - 0.0019 19.1 0.0 0.003 18.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain TPR_2 PF07719.17 VBB34022.1 - 1.5e-30 102.8 24.2 3e-05 23.8 0.2 10.1 11 1 1 12 12 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 VBB34022.1 - 7.1e-30 101.6 32.5 8.4e-07 28.6 0.5 10.1 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 VBB34022.1 - 8.6e-26 88.0 17.8 0.00031 20.6 0.0 9.9 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 VBB34022.1 - 2.2e-25 88.7 19.4 7.9e-07 29.3 0.0 7.5 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 VBB34022.1 - 1.2e-24 84.4 33.7 0.00028 20.9 0.0 11.3 11 1 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 VBB34022.1 - 5.6e-18 64.1 3.0 0.0062 17.3 0.0 7.2 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 VBB34022.1 - 7.7e-18 63.9 17.7 0.0098 16.5 0.1 10.2 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 VBB34022.1 - 1.1e-15 57.9 16.9 0.034 14.7 0.0 7.1 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 VBB34022.1 - 5.2e-14 52.6 9.6 7.6e-05 23.3 1.6 6.6 5 1 2 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.9 VBB34022.1 - 1.6e-13 50.7 0.7 7.4e-06 25.8 0.0 5.2 4 1 2 6 6 5 3 26S proteasome subunit RPN7 TPR_10 PF13374.6 VBB34022.1 - 9.2e-12 44.4 15.7 0.68 9.9 0.0 10.3 11 1 0 11 11 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB34022.1 - 1.2e-11 44.7 21.1 5.1e-05 23.4 0.2 6.2 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 VBB34022.1 - 1.7e-11 44.1 1.4 0.003 17.0 0.0 4.5 3 1 1 4 4 4 3 MalT-like TPR region TPR_11 PF13414.6 VBB34022.1 - 2.8e-10 39.7 36.6 0.00037 20.1 2.4 8.6 7 1 3 10 10 9 4 TPR repeat TPR_17 PF13431.6 VBB34022.1 - 2.6e-09 36.8 20.7 0.31 11.5 0.0 9.1 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 VBB34022.1 - 5.6e-06 26.2 6.8 0.00026 20.8 3.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 VBB34022.1 - 1.1e-05 24.9 7.9 0.008 15.4 3.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 VBB34022.1 - 3.2e-05 23.9 2.0 7.7 7.0 0.1 6.3 7 0 0 7 7 5 0 PPR repeat TPR_9 PF13371.6 VBB34022.1 - 0.00013 22.0 0.1 0.48 10.6 0.1 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 VBB34022.1 - 0.00013 21.9 15.6 0.59 10.2 0.1 6.6 7 0 0 7 7 6 2 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 VBB34022.1 - 0.00062 20.4 15.1 11 6.9 0.2 7.7 7 0 0 7 7 7 0 Sel1 repeat PPR_2 PF13041.6 VBB34022.1 - 0.00074 19.7 2.4 1.3 9.3 0.0 4.5 3 1 0 3 3 3 1 PPR repeat family TPR_5 PF12688.7 VBB34022.1 - 0.00099 19.3 0.3 4.5 7.5 0.0 4.1 6 0 0 6 6 5 1 Tetratrico peptide repeat DUF4456 PF14644.6 VBB34022.1 - 0.0013 18.4 0.1 0.0057 16.4 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF4810 PF16068.5 VBB34022.1 - 0.0048 17.4 5.6 6.8 7.3 0.0 5.2 6 1 1 7 7 4 0 Domain of unknown function (DUF4810) PknG_TPR PF16918.5 VBB34022.1 - 0.0096 14.7 0.2 6.4 5.4 0.0 3.4 3 1 1 4 4 4 0 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 VBB34022.1 - 0.014 15.4 9.4 8.1 6.6 0.2 6.0 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 VBB34022.1 - 0.02 14.5 0.3 4.8 6.8 0.1 3.6 4 0 0 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Foie-gras_1 PF11817.8 VBB34022.1 - 0.039 13.5 0.3 2.1 7.8 0.1 3.0 2 1 1 3 3 3 0 Foie gras liver health family 1 TPR_4 PF07721.14 VBB34022.1 - 0.056 14.1 0.0 51 4.9 0.0 4.4 5 0 0 5 5 2 0 Tetratricopeptide repeat DUF2992 PF11208.8 VBB34022.1 - 0.059 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) TPR_3 PF07720.12 VBB34022.1 - 0.26 11.3 30.2 4.1 7.5 1.7 7.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TAF1_subA PF14929.6 VBB34022.1 - 1.7 7.9 9.9 2.1 7.7 1.5 2.5 3 0 0 3 3 3 0 TAF RNA Polymerase I subunit A Mad3_BUB1_I PF08311.12 VBB34022.1 - 2.1 8.4 7.1 0.37 10.8 0.5 3.1 4 0 0 4 4 3 0 Mad3/BUB1 homology region 1 AF-4 PF05110.13 VBB34022.1 - 8.7 4.3 19.2 12 3.8 19.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase PF00069.25 VBB34025.1 - 4.7e-61 206.5 0.7 1.8e-45 155.4 0.4 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34025.1 - 1.1e-26 93.7 0.2 8e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 VBB34025.1 - 3.5e-05 22.9 0.1 5.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 VBB34025.1 - 0.00029 20.8 0.3 0.014 15.3 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB34025.1 - 0.0012 18.2 1.9 0.0017 17.7 0.0 2.2 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 VBB34025.1 - 0.0013 18.1 0.2 0.0027 17.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 VBB34025.1 - 0.015 14.4 0.1 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_C PF00433.24 VBB34025.1 - 0.046 14.4 3.1 0.1 13.3 3.1 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF5492 PF17596.2 VBB34026.1 - 0.05 13.9 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5492) Homeodomain PF00046.29 VBB34027.1 - 9.7e-14 51.0 3.3 2e-13 50.0 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB34027.1 - 0.12 12.3 0.5 0.12 12.3 0.5 2.2 2 0 0 2 2 2 0 Homeobox KN domain MtrF PF09472.10 VBB34028.1 - 0.045 13.2 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ShK PF01549.24 VBB34029.1 - 1.2e-13 51.3 26.4 1.6e-08 34.9 8.9 3.1 3 1 0 3 3 3 2 ShK domain-like Glycogen_syn PF05693.13 VBB34030.1 - 2.2e-255 849.2 0.3 2.6e-255 848.9 0.3 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 VBB34030.1 - 1.7e-06 27.7 0.0 5.1e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 VBB34030.1 - 3.3e-05 24.3 0.0 0.0026 18.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 VBB34030.1 - 0.021 14.8 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 C1_1 PF00130.22 VBB34032.1 - 1.2e-05 25.1 8.8 2.7e-05 24.0 8.8 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MOZ_SAS PF01853.18 VBB34033.1 - 2.9e-57 193.2 0.1 4.9e-57 192.5 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 VBB34033.1 - 8.4e-21 73.3 6.5 1.7e-20 72.3 6.5 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 VBB34033.1 - 1.5e-12 47.2 0.5 1.6e-11 43.9 0.5 2.6 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 VBB34033.1 - 0.00036 20.9 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 VBB34033.1 - 0.018 15.3 0.0 0.05 13.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family TLE_N PF03920.15 VBB34033.1 - 0.02 15.0 1.7 0.031 14.4 0.7 1.7 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain ApoO PF09769.9 VBB34034.1 - 7.7e-10 38.8 0.1 1.1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein O VPS9 PF02204.18 VBB34035.1 - 2.5e-08 34.0 0.1 2.6e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain YajC PF02699.15 VBB34035.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2140 PF09911.9 VBB34035.1 - 0.095 12.2 0.2 4.7 6.7 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MFS_1 PF07690.16 VBB34037.1 - 1.7e-18 66.7 31.1 4.7e-11 42.2 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 VBB34037.1 - 0.00033 19.3 3.7 0.00033 19.3 3.7 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 VBB34037.1 - 0.0031 16.4 11.1 0.0045 15.9 3.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 VBB34037.1 - 0.023 13.1 2.8 0.029 12.8 2.8 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Sec6 PF06046.13 VBB34041.1 - 7.4e-22 77.4 12.2 4.1e-20 71.7 10.3 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec6 DLIC PF05783.11 VBB34042.1 - 4e-06 25.9 0.0 1.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 VBB34042.1 - 8.8e-06 25.9 0.0 2.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 VBB34042.1 - 0.00043 20.3 0.2 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Ras PF00071.22 VBB34042.1 - 0.0035 16.9 0.0 0.0094 15.6 0.0 1.9 1 1 0 1 1 1 1 Ras family AAA_15 PF13175.6 VBB34042.1 - 0.0084 15.9 0.0 0.022 14.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 VBB34042.1 - 0.019 14.4 0.4 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 VBB34042.1 - 0.094 12.1 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 VBB34042.1 - 0.11 12.8 0.1 0.52 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AKAP7_RIRII_bdg PF10470.9 VBB34042.1 - 0.13 12.3 0.5 0.37 10.9 0.3 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein PP2C_C PF07830.13 VBB34042.1 - 0.35 11.3 1.3 0.84 10.1 1.3 1.6 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1397 PF07165.11 VBB34043.1 - 0.024 14.0 1.0 0.19 11.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) CD20 PF04103.15 VBB34044.1 - 7.2e-21 74.9 11.3 9e-21 74.6 11.3 1.1 1 0 0 1 1 1 1 CD20-like family Rab_bind PF16704.5 VBB34045.1 - 1.1e-14 54.2 5.4 2.8e-14 52.9 5.4 1.7 1 0 0 1 1 1 1 Rab binding domain GRIP PF01465.20 VBB34045.1 - 5.8e-13 48.5 0.3 1.3e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 GRIP domain Pex26 PF07163.12 VBB34045.1 - 0.095 12.0 2.3 0.14 11.5 2.3 1.2 1 0 0 1 1 1 0 Pex26 protein Qua1 PF16274.5 VBB34045.1 - 0.61 10.0 5.6 0.34 10.8 0.5 2.8 3 0 0 3 3 3 0 Qua1 domain Fzo_mitofusin PF04799.13 VBB34045.1 - 0.93 9.0 5.3 1.4 8.4 5.1 1.5 1 1 0 1 1 1 0 fzo-like conserved region DivIC PF04977.15 VBB34045.1 - 5.4 6.9 8.4 1.5 8.6 2.0 2.8 3 0 0 3 3 3 0 Septum formation initiator OST3_OST6 PF04756.13 VBB34046.1 - 0.091 12.1 2.6 0.11 11.9 2.6 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF805 PF05656.14 VBB34046.1 - 0.12 12.8 0.9 0.16 12.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DSPc PF00782.20 VBB34047.1 - 3.3e-27 94.9 2.0 1.8e-26 92.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF2722 PF10846.8 VBB34047.1 - 0.0007 18.7 20.1 0.00098 18.2 20.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 VBB34047.1 - 0.00077 19.6 21.5 0.00091 19.3 21.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 VBB34047.1 - 0.00095 18.6 6.1 0.0013 18.2 6.1 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Suf PF05843.14 VBB34047.1 - 0.0047 17.0 8.9 0.0076 16.3 8.9 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Med15 PF09606.10 VBB34047.1 - 0.0049 15.6 22.3 0.0063 15.3 22.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Coilin_N PF15862.5 VBB34047.1 - 0.0055 16.5 7.2 0.0055 16.5 7.2 1.8 1 1 1 2 2 2 1 Coilin N-terminus Pex14_N PF04695.13 VBB34047.1 - 0.018 15.7 10.1 0.03 15.0 10.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 VBB34047.1 - 0.042 13.9 9.9 0.059 13.4 9.9 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 UPF0560 PF10577.9 VBB34047.1 - 0.063 11.8 12.7 0.085 11.4 12.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4746 PF15928.5 VBB34047.1 - 0.07 12.5 3.2 0.11 11.9 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) eIF-3_zeta PF05091.12 VBB34047.1 - 0.073 12.0 10.9 0.094 11.7 10.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 VBB34047.1 - 0.12 12.1 4.7 0.18 11.5 4.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 VBB34047.1 - 0.27 11.6 9.5 0.42 11.0 9.5 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Pal1 PF08316.11 VBB34047.1 - 0.3 11.8 2.8 0.49 11.2 2.8 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF3371 PF11851.8 VBB34047.1 - 0.34 12.0 10.3 0.64 11.1 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF4228 PF14009.6 VBB34047.1 - 0.54 10.6 5.8 0.83 10.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 VBB34047.1 - 0.74 9.8 5.7 0.95 9.5 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 VBB34047.1 - 0.75 9.5 7.7 1 9.1 7.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 VBB34047.1 - 0.77 9.1 8.3 1.1 8.5 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 VBB34047.1 - 1.4 7.6 13.9 1 8.0 10.8 1.9 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 VBB34047.1 - 1.7 7.6 15.6 2.3 7.1 15.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CLN3 PF02487.17 VBB34047.1 - 2.2 7.3 4.7 2.8 6.9 4.7 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4175 PF13779.6 VBB34047.1 - 4.1 5.2 24.0 5.4 4.8 24.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ndc1_Nup PF09531.10 VBB34047.1 - 6.5 5.3 14.7 8.5 4.9 14.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3464 PF11947.8 VBB34047.1 - 7.6 6.3 10.5 15 5.3 10.5 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EMC3_TMCO1 PF01956.16 VBB34047.1 - 9.9 5.9 9.6 15 5.3 9.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like L27 PF02828.16 VBB34048.1 - 1.1e-07 31.5 0.1 1.9e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 L27 domain PDZ PF00595.24 VBB34048.1 - 0.021 15.2 0.0 0.05 14.0 0.0 1.7 2 0 0 2 2 2 0 PDZ domain ClpS PF02617.17 VBB34048.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Peptidase_M16 PF00675.20 VBB34049.1 - 4.8e-41 140.2 0.0 1.3e-40 138.8 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Actin PF00022.19 VBB34049.1 - 1.1e-35 123.0 0.0 1.5e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Actin Peptidase_M16_C PF05193.21 VBB34049.1 - 2.5e-13 50.4 0.0 5.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Ada_Zn_binding PF02805.16 VBB34051.1 - 0.064 13.3 0.1 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Metal binding domain of Ada zf-RING_2 PF13639.6 VBB34052.1 - 4e-09 36.7 5.6 1.8e-08 34.6 5.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 VBB34052.1 - 1.4e-06 27.9 0.3 1.4e-06 27.9 0.3 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 VBB34052.1 - 0.0024 17.7 7.5 0.05 13.4 7.5 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 VBB34052.1 - 0.016 15.5 9.9 0.095 13.0 9.9 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 VBB34052.1 - 0.023 14.6 4.8 1.7 8.6 0.9 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB34052.1 - 0.026 14.5 3.0 0.14 12.1 3.0 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 VBB34052.1 - 0.066 13.1 7.7 1.3 8.9 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 VBB34052.1 - 0.15 12.3 5.3 1.4 9.1 5.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 VBB34052.1 - 0.2 11.6 7.0 1.5 8.8 1.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 VBB34052.1 - 0.38 10.8 2.6 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger LRR_9 PF14580.6 VBB34053.1 - 1.4e-66 223.3 3.1 1.8e-66 222.9 3.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 VBB34053.1 - 3e-07 30.1 1.4 1.7e-06 27.7 0.4 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 VBB34053.1 - 3.8e-05 24.0 13.4 9.1e-05 22.8 0.8 3.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB34053.1 - 0.24 11.5 1.7 28 5.1 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat zf-CCCH PF00642.24 VBB34054.1 - 6.9e-15 54.5 15.7 1.3e-08 34.6 2.0 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 VBB34054.1 - 6.1e-09 35.6 15.1 4.6e-05 23.3 4.8 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 VBB34054.1 - 3.5e-05 23.5 10.4 0.013 15.3 2.2 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 VBB34054.1 - 0.00062 20.1 9.3 0.12 12.9 3.4 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 VBB34054.1 - 0.15 12.7 8.5 2.3 8.9 0.9 2.4 1 1 1 2 2 2 0 Torus domain dCMP_cyt_deam_1 PF00383.23 VBB34055.1 - 1.1e-17 63.8 0.4 1.4e-17 63.4 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 VBB34055.1 - 1.3e-13 51.3 1.6 2.6e-12 47.1 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 VBB34055.1 - 0.0034 17.0 1.0 1.7 8.2 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases OST3_OST6 PF04756.13 VBB34055.1 - 0.042 13.2 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family GluRS_N PF18466.1 VBB34055.1 - 0.18 12.3 0.1 31 5.1 0.1 2.7 2 1 1 3 3 3 0 Glutamate--tRNA ligase N-terminal domain PH PF00169.29 VBB34056.1 - 6.8e-09 36.2 0.4 1.1e-08 35.5 0.4 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 VBB34056.1 - 1.4e-07 31.9 0.2 2e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain Serglycin PF04360.12 VBB34056.1 - 1.3 9.0 3.4 4 7.4 2.7 2.0 1 1 1 2 2 2 0 Serglycin Thymidylat_synt PF00303.19 VBB34057.1 - 8.7e-109 362.8 0.0 1.1e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase AA_permease PF00324.21 VBB34058.1 - 3.9e-48 164.2 17.4 1.2e-38 133.0 5.8 2.0 2 0 0 2 2 2 2 Amino acid permease Menin PF05053.13 VBB34059.1 - 0.96 7.7 9.5 1 7.6 9.5 1.0 1 0 0 1 1 1 0 Menin ALMT PF11744.8 VBB34059.1 - 0.97 8.2 6.0 1.1 8.0 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 VBB34059.1 - 6.3 5.2 15.9 6.9 5.1 15.9 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 VBB34059.1 - 7 5.3 8.3 7.7 5.2 8.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4614 PF15391.6 VBB34060.1 - 0.019 15.0 0.2 0.1 12.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4614) CEBP1_N PF16368.5 VBB34060.1 - 0.11 12.0 2.1 0.25 10.8 0.3 1.9 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus Glyco_hydro_38C PF07748.13 VBB34062.1 - 2.4e-17 63.7 0.0 3.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain FRD2 PF03197.13 VBB34062.1 - 0.031 14.5 0.1 0.086 13.1 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Biopterin_H PF00351.21 VBB34063.1 - 3.9e-26 91.9 1.3 4.7e-26 91.6 0.4 1.5 2 0 0 2 2 2 1 Biopterin-dependent aromatic amino acid hydroxylase Bmp PF02608.14 VBB34063.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Ilar_coat PF01787.16 VBB34064.1 - 0.0087 15.9 1.5 0.014 15.2 1.5 1.2 1 0 0 1 1 1 1 Ilarvirus coat protein AAA_22 PF13401.6 VBB34064.1 - 0.2 11.9 1.6 0.68 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain wnt PF00110.19 VBB34065.1 - 1.2e-89 301.0 17.4 1.5e-89 300.6 17.4 1.0 1 0 0 1 1 1 1 wnt family Transglut_C PF00927.22 VBB34066.1 - 1.5e-05 25.1 0.7 0.00035 20.7 0.2 2.6 2 1 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain Collagen PF01391.18 VBB34067.1 - 0.0084 15.8 8.3 0.017 14.8 8.3 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TSP_1 PF00090.19 VBB34068.1 - 8.2e-20 70.8 38.2 7.5e-12 45.3 9.5 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain DUF4919 PF16266.5 VBB34069.1 - 0.026 14.5 0.0 0.031 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) Beta-lactamase PF00144.24 VBB34071.1 - 6e-50 170.3 0.0 8.4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Ig_3 PF13927.6 VBB34073.1 - 2e-09 37.9 1.1 0.0014 19.2 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 VBB34073.1 - 2.8e-07 30.5 0.2 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB34073.1 - 2.9e-05 24.3 0.2 0.12 12.8 0.0 3.4 2 1 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 VBB34073.1 - 0.0022 18.1 0.1 3.2 8.0 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain DUF4834 PF16118.5 VBB34073.1 - 0.0062 17.5 0.2 0.015 16.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Ntox4 PF15541.6 VBB34073.1 - 0.16 12.4 0.0 0.62 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial toxin 4 CBS PF00571.28 VBB34074.1 - 1.4e-17 63.8 0.6 1.9e-08 34.6 0.0 3.7 3 1 0 3 3 3 3 CBS domain RNA_lig_T4_1 PF09511.10 VBB34074.1 - 0.056 13.3 0.1 0.21 11.4 0.1 1.6 1 1 1 2 2 2 0 RNA ligase Carb_anhydrase PF00194.21 VBB34076.1 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.7 VBB34077.1 - 5.9e-13 49.2 1.3 4.8e-07 30.3 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB34077.1 - 8.2e-10 39.0 1.9 0.0077 16.8 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB34077.1 - 1.2e-07 31.9 2.8 0.39 11.3 0.9 4.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 VBB34077.1 - 1.7e-06 27.9 4.0 0.057 14.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 VBB34077.1 - 8.9e-06 25.9 0.1 0.019 15.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 VBB34078.1 - 9.4e-47 159.2 0.1 1.1e-46 159.1 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PFO_beta_C PF12367.8 VBB34078.1 - 0.036 14.2 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Pkinase PF00069.25 VBB34079.1 - 6.6e-31 107.6 0.3 8.4e-31 107.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34079.1 - 3.8e-20 72.3 0.1 5e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TORC_N PF12884.7 VBB34080.1 - 1.4e-19 70.7 0.0 1.4e-19 70.7 0.0 2.7 3 1 0 3 3 3 1 Transducer of regulated CREB activity, N terminus Baculo_DNA_bind PF04786.12 VBB34080.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 ssDNA binding protein Porphobil_deam PF01379.20 VBB34080.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain Zip PF02535.22 VBB34082.1 - 3.4e-19 69.3 35.7 4.5e-13 49.1 3.9 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter Orf78 PF06024.12 VBB34082.1 - 0.15 12.3 0.2 0.56 10.5 0.2 2.0 1 1 0 1 1 1 0 Orf78 (ac78) Macoilin PF09726.9 VBB34082.1 - 6.6 5.2 10.6 7.5 5.0 10.6 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 VBB34083.1 - 9.4e-16 57.9 7.0 1e-15 57.8 7.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MpPF26 PF07666.11 VBB34083.1 - 0.0041 17.2 2.1 0.0052 16.9 2.1 1.1 1 0 0 1 1 1 1 M penetrans paralogue family 26 Cytochrome-c551 PF10643.9 VBB34083.1 - 0.09 12.3 1.1 0.1 12.2 1.1 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Phage_holin_5_2 PF16079.5 VBB34083.1 - 0.29 11.5 3.3 0.72 10.2 0.1 2.3 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF2085 PF09858.9 VBB34083.1 - 0.68 10.5 3.7 2.1 8.9 3.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2085) NPA PF16469.5 VBB34084.1 - 1.5e-110 364.7 70.2 4e-29 101.7 7.8 5.3 5 0 0 5 5 5 5 Nematode polyprotein allergen ABA-1 HTH_38 PF13936.6 VBB34084.1 - 0.00074 19.2 4.5 24 4.8 0.0 5.5 5 0 0 5 5 5 1 Helix-turn-helix domain Retrotrans_gag PF03732.17 VBB34084.1 - 0.0019 18.4 1.4 0.0019 18.4 1.4 5.6 4 1 2 6 6 6 1 Retrotransposon gag protein HTH_Tnp_Tc3_1 PF11427.8 VBB34084.1 - 0.034 14.0 4.1 22 5.0 0.1 5.3 5 0 0 5 5 5 0 Tc3 transposase DUF2200 PF09966.9 VBB34084.1 - 0.69 10.1 9.8 2.1 8.5 0.5 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) PMC2NT PF08066.12 VBB34084.1 - 4.3 8.1 10.7 1.1 10.0 0.3 4.5 3 2 0 3 3 3 0 PMC2NT (NUC016) domain BTB PF00651.31 VBB34085.1 - 7.5e-29 100.2 0.3 1.3e-28 99.4 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 VBB34085.1 - 1.6e-06 28.3 0.2 3.2e-06 27.3 0.2 1.6 1 1 0 1 1 1 1 MATH domain Trehalase PF01204.18 VBB34086.1 - 1.1e-121 407.2 0.3 3e-121 405.7 0.3 1.6 1 1 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 VBB34086.1 - 0.002 17.5 1.2 0.16 11.2 0.1 2.3 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 VBB34086.1 - 0.0053 15.7 1.7 0.04 12.9 1.7 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.16 VBB34086.1 - 0.0097 14.7 0.1 0.035 12.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain DUF5013 PF16405.5 VBB34086.1 - 0.086 13.1 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5013) STPPase_N PF16891.5 VBB34086.1 - 0.19 12.2 0.1 0.37 11.3 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_15 PF00723.21 VBB34087.1 - 1.7e-14 53.5 0.0 2.1e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ldl_recept_b PF00058.17 VBB34089.1 - 7.8e-54 179.9 9.9 2.9e-10 40.4 0.0 10.4 11 0 0 11 11 11 8 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 VBB34089.1 - 1.5e-11 44.1 0.1 2e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF5050) FXa_inhibition PF14670.6 VBB34089.1 - 1.5e-09 38.0 33.0 3.1e-06 27.3 9.0 3.3 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site SGL PF08450.12 VBB34089.1 - 6.3e-09 35.8 0.9 0.3 10.6 0.0 4.5 3 2 1 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 VBB34089.1 - 0.00069 19.0 0.0 1.3 8.2 0.0 3.5 4 1 0 4 4 4 2 Lactonase, 7-bladed beta-propeller PH_14 PF17787.1 VBB34089.1 - 0.026 14.4 0.0 2.9 7.8 0.0 3.6 3 0 0 3 3 3 0 PH domain XH PF03469.14 VBB34090.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 1 0 1 1 1 0 XH domain Mucin PF01456.17 VBB34090.1 - 0.026 14.5 15.3 0.03 14.3 15.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 VBB34090.1 - 0.15 10.2 11.6 0.16 10.2 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 VBB34090.1 - 0.31 9.1 5.6 0.31 9.1 5.6 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Viral_env_E26 PF11050.8 VBB34090.1 - 9.2 5.6 7.3 34 3.7 7.3 1.8 1 1 0 1 1 1 0 Virus envelope protein E26 SUI1 PF01253.22 VBB34092.1 - 1.5e-06 28.6 0.0 2.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3338 PF11819.8 VBB34093.1 - 2.9e-31 108.3 5.6 7e-31 107.0 5.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) DUF1287 PF06940.11 VBB34093.1 - 0.03 14.0 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF4564 PF15169.6 VBB34093.1 - 0.59 9.8 3.9 0.39 10.4 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4564) Ig_3 PF13927.6 VBB34094.1 - 1.5e-15 57.5 0.0 2e-12 47.5 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 VBB34094.1 - 2.1e-12 47.2 0.0 8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 VBB34094.1 - 2.1e-10 40.5 0.0 6.2e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 VBB34094.1 - 3.6e-09 36.7 0.0 1.2e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 VBB34094.1 - 6.2e-05 23.1 0.0 0.0022 18.1 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 VBB34094.1 - 0.00017 21.6 0.0 0.043 13.9 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 VBB34094.1 - 0.015 15.3 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain SSP160 PF06933.11 VBB34095.1 - 0.66 8.1 3.5 0.8 7.8 3.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TF_AP-2 PF03299.14 VBB34096.1 - 4.4e-39 134.5 0.0 4.4e-39 134.5 0.0 2.4 2 1 0 2 2 2 1 Transcription factor AP-2 Macoilin PF09726.9 VBB34096.1 - 0.004 15.8 10.4 0.0048 15.5 10.4 1.1 1 0 0 1 1 1 1 Macoilin family DDHD PF02862.17 VBB34096.1 - 0.014 15.5 5.2 0.018 15.2 5.2 1.3 1 0 0 1 1 1 0 DDHD domain Baculo_PP31 PF05311.11 VBB34096.1 - 0.04 13.4 6.3 0.056 12.9 6.3 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Otopetrin PF03189.13 VBB34096.1 - 0.18 10.6 5.2 0.3 9.9 5.2 1.4 1 0 0 1 1 1 0 Otopetrin DUF4407 PF14362.6 VBB34096.1 - 0.43 9.9 6.1 0.57 9.5 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 VBB34096.1 - 0.68 8.9 12.6 0.85 8.5 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 VBB34096.1 - 0.72 8.8 10.4 0.94 8.4 10.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 VBB34096.1 - 0.77 9.9 6.5 1.4 9.0 6.5 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S49_N PF08496.10 VBB34096.1 - 0.85 9.7 6.6 2 8.5 6.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GREB1 PF15782.5 VBB34096.1 - 0.86 6.6 17.3 1 6.4 17.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 VBB34096.1 - 1.1 8.3 11.5 1.7 7.6 11.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 VBB34096.1 - 1.8 8.5 10.4 2.7 8.0 10.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4647 PF15504.6 VBB34096.1 - 1.9 7.5 17.6 1.8 7.6 16.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4647) LMBR1 PF04791.16 VBB34096.1 - 2.2 7.1 9.0 3.1 6.6 9.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 VBB34096.1 - 2.2 7.0 9.0 2.7 6.7 9.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 VBB34096.1 - 2.4 6.8 13.4 2.9 6.6 13.4 1.2 1 0 0 1 1 1 0 Presenilin DivIC PF04977.15 VBB34096.1 - 3.1 7.7 11.5 11 5.9 11.5 1.9 1 0 0 1 1 1 0 Septum formation initiator Connexin PF00029.19 VBB34096.1 - 3.1 7.5 8.0 5.4 6.7 8.0 1.3 1 0 0 1 1 1 0 Connexin GTA_holin_3TM PF11351.8 VBB34096.1 - 4.1 8.0 8.7 4.5 7.8 6.0 2.3 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release FAM176 PF14851.6 VBB34096.1 - 4.1 7.0 7.1 7.9 6.1 7.1 1.4 1 0 0 1 1 1 0 FAM176 family DUF3381 PF11861.8 VBB34096.1 - 5.6 6.7 12.2 11 5.8 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) EIIBC-GUT_N PF03612.14 VBB34096.1 - 6.5 6.4 8.4 13 5.5 8.4 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.8 VBB34096.1 - 7.3 6.3 9.2 28 4.5 8.8 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Med15 PF09606.10 VBB34096.1 - 7.7 5.1 41.8 11 4.6 41.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CLN3 PF02487.17 VBB34096.1 - 8.3 5.3 9.3 2.6 7.0 6.6 1.5 2 0 0 2 2 2 0 CLN3 protein zf-C3HC4 PF00097.25 VBB34097.1 - 2.3e-05 24.1 11.4 5.6e-05 22.9 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB34097.1 - 6.3e-05 23.2 11.1 0.00014 22.1 11.1 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 VBB34097.1 - 0.0019 18.0 9.3 0.0064 16.3 9.3 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 VBB34097.1 - 0.0036 17.3 7.6 0.0036 17.3 7.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 VBB34097.1 - 0.0063 16.7 11.4 0.013 15.6 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 VBB34097.1 - 0.17 11.9 11.1 0.42 10.6 11.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 VBB34097.1 - 0.58 10.0 6.1 1.8 8.4 6.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 VBB34097.1 - 3.5 7.6 15.2 1.5 8.7 12.1 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PDZ_2 PF13180.6 VBB34098.1 - 1.2e-16 60.8 11.8 0.0099 16.2 0.2 5.4 4 1 1 5 5 5 5 PDZ domain PDZ_6 PF17820.1 VBB34098.1 - 5.4e-16 58.2 5.4 0.00041 20.1 0.1 5.5 4 1 1 5 5 5 5 PDZ domain PDZ PF00595.24 VBB34098.1 - 7.8e-14 51.8 10.1 0.00044 20.6 0.1 5.4 4 1 1 5 5 5 5 PDZ domain Tricorn_PDZ PF14685.6 VBB34098.1 - 1.1e-07 31.7 4.2 0.097 12.6 0.1 5.3 4 1 1 5 5 5 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 VBB34098.1 - 0.016 15.2 1.7 3.5 7.7 0.1 3.5 3 2 0 3 3 3 0 PDZ-like domain Tnp_22_trimer PF17489.2 VBB34098.1 - 0.08 12.9 0.2 5 7.2 0.0 2.7 2 0 0 2 2 2 0 L1 transposable element trimerization domain PDZ_4 PF17816.1 VBB34098.1 - 0.13 12.7 2.4 7.7 7.0 0.0 3.6 4 0 0 4 4 4 0 PDZ domain SH3_1 PF00018.28 VBB34100.1 - 3.9e-07 29.6 0.0 9.4e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 VBB34100.1 - 4e-07 29.8 0.1 1.6e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB34100.1 - 0.00038 20.1 0.0 0.00083 19.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1308 PF07000.11 VBB34100.1 - 0.067 13.1 0.1 3.3 7.6 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1308) DUF4894 PF16235.5 VBB34100.1 - 0.1 13.0 0.5 6.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4894) SUIM_assoc PF16619.5 VBB34101.1 - 8.2 6.6 10.3 5.7 7.1 4.1 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ESSS PF10183.9 VBB34102.1 - 0.1 12.8 0.2 0.15 12.3 0.2 1.5 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rho_GDI PF02115.17 VBB34103.1 - 1.9e-59 200.7 0.0 2.2e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SH3_5 PF08460.10 VBB34103.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain CopC PF04234.12 VBB34103.1 - 0.033 15.2 0.0 0.064 14.3 0.0 1.5 1 0 0 1 1 1 0 CopC domain Thyroglobulin_1 PF00086.18 VBB34105.1 - 6.8e-18 64.1 2.3 1.9e-17 62.7 2.3 1.8 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 VBB34105.1 - 1.4e-12 47.9 0.1 2.2e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 VBB34105.1 - 1.6e-06 28.1 4.7 1.7e-06 28.0 2.2 2.4 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 VBB34105.1 - 2.2e-05 24.3 8.6 3.7e-05 23.7 4.1 2.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.6 VBB34105.1 - 4.6e-05 23.0 0.1 0.064 13.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 VBB34105.1 - 0.00031 20.1 0.0 0.1 12.2 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 VBB34105.1 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 VBB34105.1 - 0.0025 17.2 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 EF hand Dockerin_1 PF00404.18 VBB34105.1 - 0.043 14.0 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Dockerin type I domain CTP_transf_like PF01467.26 VBB34106.1 - 4.1e-49 166.5 0.1 3.3e-28 98.7 0.0 2.9 3 0 0 3 3 3 2 Cytidylyltransferase-like FAD_syn PF06574.12 VBB34106.1 - 0.014 15.2 2.9 4.6 7.1 0.2 3.2 3 0 0 3 3 3 0 FAD synthetase SUZ PF12752.7 VBB34107.1 - 5.4e-15 55.9 0.1 9.6e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 SUZ domain Na_Ca_ex PF01699.24 VBB34109.1 - 2.4e-28 99.0 19.8 3.3e-28 98.5 19.8 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF2567 PF10821.8 VBB34109.1 - 0.07 13.2 0.2 0.07 13.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2567) MAP17 PF15807.5 VBB34110.1 - 0.016 15.4 2.9 0.038 14.2 2.9 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RSN1_TM PF13967.6 VBB34110.1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DIRP PF06584.13 VBB34110.1 - 0.099 12.8 1.1 0.25 11.6 1.1 1.7 1 0 0 1 1 1 0 DIRP CLN3 PF02487.17 VBB34110.1 - 0.12 11.4 0.7 0.26 10.3 0.7 1.5 1 0 0 1 1 1 0 CLN3 protein TssO PF17561.2 VBB34110.1 - 0.17 12.0 6.6 0.032 14.3 2.2 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF4065 PF13274.6 VBB34110.1 - 1.7 9.5 6.2 4.2 8.3 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) zf-RING_2 PF13639.6 VBB34111.1 - 1.7e-11 44.2 9.5 1.7e-11 44.2 9.5 1.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 VBB34111.1 - 7.4e-09 35.2 5.9 7.4e-09 35.2 5.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 VBB34111.1 - 2.5e-07 30.6 6.7 2.5e-07 30.6 6.7 1.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 VBB34111.1 - 8.7e-07 28.7 9.4 1.8e-06 27.7 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 VBB34111.1 - 6.3e-06 26.0 7.4 1.2e-05 25.1 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB34111.1 - 6.6e-06 25.9 5.3 1.2e-05 25.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB34111.1 - 0.00026 20.9 5.6 0.00026 20.9 5.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 VBB34111.1 - 0.0022 18.3 12.2 0.0022 18.3 12.2 2.2 2 1 1 3 3 2 1 RING-H2 zinc finger domain FANCL_C PF11793.8 VBB34111.1 - 0.0029 17.7 8.9 0.067 13.4 8.9 2.5 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 VBB34111.1 - 0.02 14.5 5.2 0.02 14.5 5.2 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 VBB34111.1 - 0.023 14.7 7.5 0.17 11.9 7.8 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lenti_VIF_2 PF07401.12 VBB34111.1 - 0.04 13.3 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein Prok-RING_4 PF14447.6 VBB34111.1 - 0.077 12.9 10.7 7.8 6.4 11.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Phage_Treg PF04761.12 VBB34112.1 - 0.0015 18.6 0.0 0.0042 17.2 0.0 1.7 2 0 0 2 2 2 1 Lactococcus bacteriophage putative transcription regulator Phage_Orf51 PF06194.11 VBB34112.1 - 0.0091 16.0 0.0 2.8 8.0 0.0 2.2 1 1 0 2 2 2 2 Phage Conserved Open Reading Frame 51 Pet100 PF09803.9 VBB34112.1 - 0.024 15.1 0.0 0.074 13.6 0.0 1.8 1 1 1 2 2 2 0 Pet100 SEA PF01390.20 VBB34113.1 - 1.7e-05 24.8 0.1 2.3e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 SEA domain RQC PF09382.10 VBB34114.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 RQC domain SieB PF14163.6 VBB34115.1 - 0.006 16.1 0.2 0.009 15.5 0.2 1.3 1 0 0 1 1 1 1 Super-infection exclusion protein B Comm PF15957.5 VBB34115.1 - 0.0082 16.5 0.5 0.014 15.7 0.1 1.6 2 0 0 2 2 2 1 Commissureless HemY_N PF07219.13 VBB34115.1 - 0.0093 16.1 0.1 0.0093 16.1 0.1 1.5 2 0 0 2 2 2 1 HemY protein N-terminus Adeno_E3B PF03376.14 VBB34115.1 - 0.012 15.9 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3B protein MFS_Mycoplasma PF07672.13 VBB34115.1 - 0.024 13.9 0.5 0.031 13.5 0.5 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter COX2_TM PF02790.15 VBB34115.1 - 0.05 13.8 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain F-box PF00646.33 VBB34119.1 - 0.011 15.5 0.8 0.034 14.0 0.8 1.8 1 0 0 1 1 1 0 F-box domain FliG_N PF14842.6 VBB34120.1 - 0.0014 19.1 3.6 0.0014 19.1 3.6 2.7 3 0 0 3 3 3 1 FliG N-terminal domain Patched PF02460.18 VBB34121.1 - 0.33 9.0 3.2 0.49 8.4 3.2 1.2 1 0 0 1 1 1 0 Patched family Dimer_Tnp_hAT PF05699.14 VBB34123.1 - 2.3e-09 36.9 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Imm19 PF15563.6 VBB34124.1 - 0.0042 16.6 0.0 0.005 16.4 0.0 1.0 1 0 0 1 1 1 1 Immunity protein 19 Exog_C PF18026.1 VBB34124.1 - 0.073 13.1 0.6 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain AP_endonuc_2 PF01261.24 VBB34124.1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel FlgN PF05130.12 VBB34125.1 - 0.0045 17.5 3.3 0.0045 17.5 3.3 3.2 1 1 2 3 3 3 2 FlgN protein DivIC PF04977.15 VBB34125.1 - 0.012 15.4 4.2 0.012 15.4 4.2 4.9 4 2 0 4 4 4 0 Septum formation initiator DUF4090 PF13319.6 VBB34125.1 - 0.033 14.4 0.5 0.033 14.4 0.5 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF4090) Nup54_57_C PF18570.1 VBB34125.1 - 4.6 6.9 9.8 0.68 9.6 0.2 3.3 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain tRNA_SAD PF07973.14 VBB34127.1 - 0.00042 20.3 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Ribosomal_S7e PF01251.18 VBB34129.1 - 1.2e-84 282.7 4.7 1.3e-84 282.5 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Neur_chan_LBD PF02931.23 VBB34130.1 - 1.4e-21 77.0 0.1 1.9e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB34130.1 - 7.9e-20 71.9 0.8 6.7e-17 62.3 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Lactamase_B_4 PF13691.6 VBB34131.1 - 0.034 13.8 0.1 0.065 12.9 0.1 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease PBD PF00786.28 VBB34132.1 - 1.6e-10 41.1 2.2 1.9e-10 40.9 0.1 2.1 3 0 0 3 3 3 1 P21-Rho-binding domain Atg14 PF10186.9 VBB34133.1 - 2.3e-13 49.9 7.8 3.9e-13 49.2 7.8 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 VBB34133.1 - 0.0016 18.3 0.6 0.0016 18.3 0.6 1.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain EzrA PF06160.12 VBB34133.1 - 0.0018 16.6 2.1 0.0027 16.0 2.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Tektin PF03148.14 VBB34133.1 - 0.0019 17.0 1.6 0.0028 16.5 1.6 1.2 1 0 0 1 1 1 1 Tektin family Spc7 PF08317.11 VBB34133.1 - 0.014 14.3 1.1 0.022 13.7 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 VBB34133.1 - 0.32 11.1 4.8 2 8.6 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor C2 PF00168.30 VBB34134.1 - 2.4e-46 156.3 0.6 4.4e-23 81.5 0.4 2.1 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 VBB34134.1 - 8e-05 22.3 0.0 0.23 11.0 0.0 2.4 2 1 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.6 VBB34134.1 - 0.00039 20.3 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins YedD PF13987.6 VBB34134.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 YedD-like protein DUF4138 PF13595.6 VBB34134.1 - 0.058 12.7 1.2 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4138) EFG_II PF14492.6 VBB34134.1 - 0.14 12.2 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II Cation_efflux PF01545.21 VBB34136.1 - 1.1e-24 87.3 12.8 1.5e-24 86.9 12.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 VBB34136.1 - 8.4e-07 29.0 3.2 8.4e-07 29.0 3.2 1.6 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter NEMP PF10225.9 VBB34136.1 - 0.0047 16.6 1.7 0.0047 16.6 1.7 2.2 2 1 1 3 3 3 1 NEMP family Voltage_CLC PF00654.20 VBB34136.1 - 0.014 14.7 2.8 0.037 13.3 3.1 1.5 1 1 0 1 1 1 0 Voltage gated chloride channel FTCD_C PF04961.12 VBB34136.1 - 0.025 14.4 0.1 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase COX1 PF00115.20 VBB34136.1 - 0.087 11.7 4.5 0.12 11.2 4.5 1.2 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF1282 PF06930.12 VBB34136.1 - 0.73 9.6 9.6 0.077 12.8 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) VWA PF00092.28 VBB34137.1 - 8.2e-43 146.7 0.5 1.2e-42 146.2 0.5 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.15 VBB34137.1 - 1.3e-35 121.4 112.2 1.4e-07 31.6 4.7 10.6 10 0 0 10 10 10 7 Calcium-binding EGF domain EGF_3 PF12947.7 VBB34137.1 - 2.8e-30 104.2 116.5 3.5e-07 30.3 7.7 10.9 9 1 1 10 10 10 8 EGF domain hEGF PF12661.7 VBB34137.1 - 3.1e-21 75.2 93.9 5.3e-05 23.7 0.7 12.1 11 0 0 11 11 11 7 Human growth factor-like EGF EGF PF00008.27 VBB34137.1 - 4.3e-21 74.9 113.6 3.6e-05 24.0 3.2 11.3 10 1 0 10 10 10 7 EGF-like domain VWA_2 PF13519.6 VBB34137.1 - 2e-17 63.8 0.0 4.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_MSP1_1 PF12946.7 VBB34137.1 - 1.7e-09 37.6 94.1 0.00037 20.5 7.6 9.8 11 1 0 11 11 11 7 MSP1 EGF domain 1 FXa_inhibition PF14670.6 VBB34137.1 - 2e-09 37.6 108.7 0.011 16.0 3.0 10.8 9 1 1 10 10 10 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB34137.1 - 0.00014 21.7 72.1 0.014 15.3 0.3 10.7 11 0 0 11 11 11 6 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 VBB34137.1 - 0.0015 18.8 101.5 0.0033 17.7 7.5 9.3 9 0 0 9 9 9 5 Pvs28 EGF domain ClpB_D2-small PF10431.9 VBB34137.1 - 0.026 14.6 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein ELO PF01151.18 VBB34138.1 - 1.1e-55 188.9 28.6 1.5e-55 188.5 28.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1689 PF07954.11 VBB34138.1 - 0.83 10.1 5.7 1.6 9.1 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Patched PF02460.18 VBB34139.1 - 9.3e-165 549.9 21.7 1.2e-164 549.6 21.7 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB34139.1 - 3.3e-26 92.0 19.7 1.5e-24 86.6 2.7 3.0 2 1 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 VBB34139.1 - 1.2e-05 23.3 3.8 1.2e-05 23.3 3.8 1.6 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Med9 PF07544.13 VBB34139.1 - 0.039 14.0 1.7 0.11 12.6 1.1 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Aminotran_1_2 PF00155.21 VBB34140.1 - 1e-30 107.2 0.0 1.2e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 VBB34140.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase NanE PF04131.14 VBB34140.1 - 0.053 12.7 0.0 0.29 10.3 0.0 2.2 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase 6PF2K PF01591.18 VBB34141.1 - 5.9e-89 297.2 0.0 7e-89 296.9 0.0 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 VBB34141.1 - 1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 VBB34141.1 - 0.0065 16.9 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 VBB34141.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 VBB34141.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 VBB34141.1 - 0.18 11.1 0.0 0.55 9.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Lectin_C PF00059.21 VBB34143.1 - 2.5e-15 57.1 0.0 4.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain CRAL_TRIO PF00650.20 VBB34145.1 - 1.1e-06 28.4 0.0 4.9e-05 23.1 0.0 2.3 1 1 1 2 2 2 1 CRAL/TRIO domain dCache_1 PF02743.18 VBB34145.1 - 0.015 15.1 0.0 0.36 10.6 0.0 2.2 1 1 1 2 2 2 0 Cache domain DUF1967 PF09269.11 VBB34145.1 - 0.046 13.7 0.3 0.54 10.2 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) AP_endonuc_2 PF01261.24 VBB34145.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel RuvB_N PF05496.12 VBB34146.1 - 0.034 13.9 0.0 0.081 12.7 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain CC2D2AN-C2 PF15625.6 VBB34148.1 - 1.2e-26 93.5 0.0 2.5e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 VBB34148.1 - 7.9e-08 32.5 0.1 4.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain V_ATPase_I_N PF18670.1 VBB34150.1 - 0.12 12.8 1.0 0.54 10.7 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain ADAM_spacer1 PF05986.14 VBB34154.1 - 6.7e-30 103.5 0.1 9.8e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 VBB34154.1 - 9.1e-23 80.2 42.5 2.3e-07 30.9 10.1 5.1 4 0 0 4 4 4 4 Thrombospondin type 1 domain Spc7 PF08317.11 VBB34155.1 - 0.00075 18.5 13.9 0.0048 15.8 7.0 3.0 3 0 0 3 3 3 1 Spc7 kinetochore protein Nup54 PF13874.6 VBB34155.1 - 0.0025 17.9 7.1 0.0025 17.9 7.1 2.7 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Lebercilin PF15619.6 VBB34155.1 - 0.0077 15.9 12.3 0.0077 15.9 12.3 2.1 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.18 VBB34155.1 - 0.05 13.9 7.5 0.14 12.5 0.2 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family Viral_P18 PF04521.13 VBB34155.1 - 0.11 12.3 0.8 0.33 10.7 0.8 1.8 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1664 PF07889.12 VBB34155.1 - 0.12 12.4 4.4 1.1 9.3 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 VBB34155.1 - 0.16 12.4 8.7 0.46 10.9 0.5 3.4 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-F_leu_zip PF10473.9 VBB34155.1 - 0.19 11.7 13.0 2.4 8.2 9.5 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PEARLI-4 PF05278.12 VBB34155.1 - 0.49 9.9 8.1 0.6 9.7 0.4 2.8 2 1 1 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) NPV_P10 PF05531.12 VBB34155.1 - 0.59 10.6 3.8 9.9 6.7 0.1 3.1 4 0 0 4 4 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 VBB34155.1 - 1.4 9.4 7.2 6 7.4 0.2 2.8 2 1 0 2 2 2 0 Snapin/Pallidin YabA PF06156.13 VBB34155.1 - 1.6 9.4 8.0 2.9 8.6 3.8 3.0 2 1 0 2 2 2 0 Initiation control protein YabA PspA_IM30 PF04012.12 VBB34155.1 - 2 8.0 9.7 1.3 8.5 0.7 3.1 3 0 0 3 3 3 0 PspA/IM30 family FliD_N PF02465.18 VBB34155.1 - 2.2 9.1 7.0 1.1 10.0 1.5 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus cwf21 PF08312.12 VBB34155.1 - 2.8 8.2 7.8 32 4.8 7.8 2.5 1 1 0 1 1 1 0 cwf21 domain Lzipper-MIP1 PF14389.6 VBB34155.1 - 3.8 7.9 10.6 5.1 7.5 6.4 3.2 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FAM76 PF16046.5 VBB34155.1 - 5.7 6.2 8.4 10 5.3 8.4 1.5 1 0 0 1 1 1 0 FAM76 protein Uso1_p115_C PF04871.13 VBB34155.1 - 8.2 6.8 11.2 0.44 10.9 3.6 2.7 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2205 PF10224.9 VBB34155.1 - 9.1 6.4 10.4 0.19 11.7 1.8 2.6 3 1 1 4 4 4 0 Short coiled-coil protein SlyX PF04102.12 VBB34155.1 - 9.9 6.9 14.8 11 6.7 2.8 3.8 3 1 0 3 3 3 0 SlyX Collagen PF01391.18 VBB34156.1 - 2.3e-21 75.3 94.2 2.1e-09 37.0 30.9 4.4 3 1 0 4 4 4 3 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB34156.1 - 1e-19 70.3 0.0 1.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain PCI PF01399.27 VBB34158.1 - 1.6e-12 47.8 0.5 2.3e-11 44.1 0.0 2.5 2 0 0 2 2 2 1 PCI domain STAT_int PF02865.17 VBB34158.1 - 0.014 15.9 0.7 0.032 14.7 0.1 1.9 2 0 0 2 2 2 0 STAT protein, protein interaction domain A_thal_3526 PF09713.10 VBB34158.1 - 0.016 15.4 0.2 0.052 13.8 0.2 1.9 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Linker_histone PF00538.19 VBB34158.1 - 0.075 13.4 0.2 0.93 9.9 0.0 2.4 2 0 0 2 2 2 0 linker histone H1 and H5 family FeoC PF09012.10 VBB34158.1 - 0.13 12.3 0.3 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator LRR_4 PF12799.7 VBB34159.1 - 7.6e-37 124.7 35.3 7.1e-09 35.8 0.7 7.3 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB34159.1 - 4.1e-22 78.5 18.9 2e-08 34.0 0.7 3.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 VBB34159.1 - 3.2e-20 71.6 23.0 1.8e-06 27.6 1.2 6.2 3 1 3 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 VBB34159.1 - 2.3e-05 24.1 11.0 4.3 7.6 0.1 7.2 6 1 1 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 VBB34159.1 - 0.0016 18.7 23.2 13 6.8 0.1 8.9 9 1 0 9 9 9 2 Leucine Rich Repeat DUF4538 PF15061.6 VBB34159.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Serpin PF00079.20 VBB34160.1 - 5.8e-26 91.7 5.2 7.4e-26 91.3 5.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) HU-CCDC81_euk_1 PF14908.6 VBB34162.1 - 0.13 12.4 0.0 10 6.3 0.0 2.4 1 1 1 2 2 2 0 CCDC81 eukaryotic HU domain 1 CAP PF00188.26 VBB34163.1 - 0.027 15.3 0.0 0.035 14.9 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich secretory protein family bZIP_1 PF00170.21 VBB34164.1 - 2.8e-09 36.9 14.2 4.6e-09 36.2 14.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 VBB34164.1 - 3.9e-06 26.8 11.9 6.7e-06 26.1 11.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 VBB34164.1 - 0.0001 22.8 8.4 0.00021 21.7 8.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor CAS_C PF12026.8 VBB34164.1 - 0.044 13.9 0.7 0.084 13.0 0.7 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Tox-ODYAM1 PF15642.6 VBB34164.1 - 0.41 9.6 3.5 0.56 9.1 3.5 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TSNAXIP1_N PF15739.5 VBB34164.1 - 1.2 9.5 6.0 2 8.8 6.0 1.3 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF1501 PF07394.12 VBB34164.1 - 1.4 7.9 3.9 1.1 8.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) PVL_ORF50 PF07768.11 VBB34164.1 - 2.5 8.5 8.3 1.6 9.1 5.8 1.9 1 1 0 1 1 1 0 PVL ORF-50-like family Y_phosphatase PF00102.27 VBB34166.1 - 8e-42 143.4 1.5 8.9e-42 143.3 1.5 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nudix_N_2 PF14803.6 VBB34166.1 - 0.13 12.2 0.8 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Nudix N-terminal Pkinase PF00069.25 VBB34167.1 - 1.6e-21 76.9 0.1 1.7e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34167.1 - 2.2e-14 53.4 0.1 2.6e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Myco_arth_vir_N PF09610.10 VBB34168.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Ski_Sno PF02437.17 VBB34170.1 - 7.7e-29 99.6 0.7 1.4e-28 98.7 0.1 1.7 2 0 0 2 2 2 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 VBB34170.1 - 2.3e-22 79.0 0.6 3.7e-22 78.4 0.6 1.3 1 0 0 1 1 1 1 c-SKI Smad4 binding domain TSC22 PF01166.18 VBB34171.1 - 0.14 12.5 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Chorion_2 PF03964.15 VBB34172.1 - 0.038 14.8 1.3 0.038 14.8 1.3 1.8 1 1 1 2 2 2 0 Chorion family 2 CytochromB561_N PF09786.9 VBB34172.1 - 0.29 10.1 6.4 0.32 9.9 6.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SR-25 PF10500.9 VBB34172.1 - 2.3 7.8 24.7 3.8 7.1 24.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhlB PF12300.8 VBB34172.1 - 4.8 7.3 10.9 2.1 8.5 8.5 1.5 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Cadherin PF00028.17 VBB34173.1 - 2.9e-40 136.6 7.7 1.9e-11 44.2 0.1 6.7 7 0 0 7 7 7 5 Cadherin domain Cadherin_pro PF08758.11 VBB34173.1 - 0.001 19.2 0.0 2.4 8.4 0.0 4.7 5 0 0 5 5 5 1 Cadherin prodomain like Cadherin_2 PF08266.12 VBB34173.1 - 0.0026 17.5 1.0 1.6 8.6 0.1 4.0 4 1 0 4 4 4 1 Cadherin-like NDT80_PhoG PF05224.12 VBB34173.1 - 0.093 12.9 0.3 12 6.0 0.1 3.1 3 0 0 3 3 3 0 NDT80 / PhoG like DNA-binding family Glyco_hydro2_C5 PF18565.1 VBB34173.1 - 0.19 11.6 0.7 0.98 9.3 0.2 2.4 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 C2-C2_1 PF11618.8 VBB34174.1 - 5.3e-33 114.1 0.0 5.3e-26 91.4 0.3 2.6 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 C2 PF00168.30 VBB34174.1 - 3.1e-07 30.6 0.0 6.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain MCC-bdg_PDZ PF10506.9 VBB34174.1 - 0.026 14.5 0.9 0.069 13.2 0.9 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PKcGMP_CC PF16808.5 VBB34174.1 - 0.067 13.0 0.9 0.18 11.7 0.9 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3585 PF12130.8 VBB34175.1 - 2e-20 73.3 18.5 3e-20 72.7 18.5 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DUF5446 PF17522.2 VBB34175.1 - 0.0029 17.8 7.0 0.11 12.7 4.9 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5446) EF-G-binding_N PF07299.11 VBB34175.1 - 0.039 14.5 5.8 0.11 13.0 1.7 2.6 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal RVT_3 PF13456.6 VBB34175.1 - 0.1 12.4 0.9 0.42 10.4 0.2 2.1 1 1 0 2 2 2 0 Reverse transcriptase-like H-kinase_dim PF02895.14 VBB34175.1 - 0.11 12.9 0.7 0.11 12.9 0.7 3.1 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF4061 PF13270.6 VBB34175.1 - 0.15 12.4 5.0 0.15 12.4 2.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) FapA PF03961.13 VBB34175.1 - 0.36 9.4 8.7 0.83 8.2 8.8 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 VBB34175.1 - 0.51 10.4 4.5 0.4 10.7 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 VBB34175.1 - 6.6 7.1 11.7 0.31 11.3 0.8 3.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain FERM_C PF09380.10 VBB34176.1 - 0.00042 20.6 0.1 0.00097 19.5 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 VBB34176.1 - 0.0052 17.2 0.1 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 FERM central domain Nop53 PF07767.11 VBB34177.1 - 1.3e-56 192.7 30.5 1.3e-56 192.7 30.5 1.7 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) TTR-52 PF01060.23 VBB34178.1 - 3e-15 56.7 0.0 7.4e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 Transthyretin-like family TTR-52 PF01060.23 VBB34179.1 - 1.5e-20 73.6 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Transthyretin-like family Collagen PF01391.18 VBB34180.1 - 2e-11 43.5 37.7 2.9e-09 36.5 37.7 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Zona_pellucida PF00100.23 VBB34182.1 - 3.4e-11 43.4 3.3 3.4e-11 43.4 3.3 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain CAP PF00188.26 VBB34183.1 - 3.2e-22 79.7 0.3 4.1e-22 79.3 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Homeodomain PF00046.29 VBB34184.1 - 1.1e-21 76.4 2.3 1.7e-21 75.8 2.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 VBB34184.1 - 7.4e-08 32.2 0.4 2.2e-07 30.6 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain DEAD PF00270.29 VBB34185.1 - 1.1e-06 28.6 0.1 3e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 VBB34185.1 - 8.6e-06 26.1 0.2 2.4e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 VBB34185.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 VBB34185.1 - 0.0044 17.0 0.4 0.019 14.9 0.4 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 VBB34185.1 - 0.0045 16.1 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 VBB34185.1 - 0.011 15.7 0.0 0.049 13.6 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 VBB34185.1 - 0.037 14.4 0.4 0.13 12.6 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 VBB34185.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 VBB34185.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 VBB34185.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 VBB34185.1 - 2.1 8.8 4.5 1.1 9.8 0.2 2.4 2 1 1 3 3 3 0 ABC transporter PRA1 PF03208.19 VBB34186.1 - 1.5e-09 37.7 2.8 1.9e-09 37.3 2.8 1.1 1 0 0 1 1 1 1 PRA1 family protein TMEM208_SND2 PF05620.11 VBB34186.1 - 7.7 6.3 6.9 0.76 9.5 0.3 2.2 1 1 2 3 3 3 0 SRP-independent targeting protein 2/TMEM208 TFIIS_M PF07500.14 VBB34187.1 - 1.1e-30 106.4 1.3 1.1e-30 106.4 1.3 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 VBB34187.1 - 5.5e-13 48.7 1.9 1e-12 47.9 1.9 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.18 VBB34187.1 - 4.3e-12 45.7 1.6 4.3e-12 45.7 1.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Ku_C PF03730.14 VBB34187.1 - 0.13 13.0 0.8 0.3 11.8 0.1 2.0 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm zf-ZPR1 PF03367.13 VBB34188.1 - 2.2e-106 352.6 8.5 2.6e-55 186.6 2.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain RNHCP PF12647.7 VBB34188.1 - 0.12 12.3 2.1 8 6.5 0.0 3.3 3 0 0 3 3 3 0 RNHCP domain Zn-ribbon_8 PF09723.10 VBB34188.1 - 8.3 6.6 11.8 6.8 6.9 0.2 3.8 4 0 0 4 4 4 0 Zinc ribbon domain 7TM_GPCR_Srw PF10324.9 VBB34189.1 - 1.8e-33 116.2 19.7 4.1e-33 115.0 19.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 VBB34189.1 - 0.00044 19.7 20.3 0.01 15.2 20.3 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_90 PF05686.12 VBB34190.1 - 2.3e-22 79.5 0.9 2.6e-22 79.3 0.9 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 EMP24_GP25L PF01105.24 VBB34191.1 - 1.2e-38 132.8 0.1 1.4e-38 132.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4115 PF13464.6 VBB34191.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) eRF1_2 PF03464.15 VBB34192.1 - 3.6e-47 160.0 0.1 5.9e-47 159.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 VBB34192.1 - 1.2e-34 119.2 0.3 3.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 VBB34192.1 - 1.2e-18 67.3 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 VBB34192.1 - 1.8e-09 38.0 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 VBB34192.1 - 7.8e-09 35.9 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Defensin_beta PF00711.19 VBB34193.1 - 0.039 14.0 0.7 7.5 6.7 0.3 2.4 2 0 0 2 2 2 0 Beta defensin FA_desaturase PF00487.24 VBB34194.1 - 0.041 13.7 2.4 2.9 7.7 0.0 2.5 3 0 0 3 3 3 0 Fatty acid desaturase SSP160 PF06933.11 VBB34194.1 - 0.09 11.0 4.2 0.12 10.6 4.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 E1-E2_ATPase PF00122.20 VBB34194.1 - 0.13 11.8 3.6 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 E1-E2 ATPase 7TM_GPCR_Srw PF10324.9 VBB34195.1 - 0.00068 19.0 8.9 0.0023 17.3 8.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Trypsin PF00089.26 VBB34196.1 - 3.6e-06 26.9 0.1 3.8e-06 26.9 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 VBB34196.1 - 0.039 13.5 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 DUF2868 PF11067.8 VBB34198.1 - 0.17 11.4 0.1 0.21 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MFMR_assoc PF16596.5 VBB34198.1 - 0.22 12.0 5.4 0.38 11.2 5.4 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR DUF4407 PF14362.6 VBB34198.1 - 2.6 7.3 5.6 3.6 6.9 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kelch_6 PF13964.6 VBB34200.1 - 3.3e-25 87.5 13.3 1.6e-07 31.3 0.6 6.0 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 VBB34200.1 - 3.6e-24 84.1 16.4 1.3e-06 27.9 0.4 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 VBB34200.1 - 3.9e-23 81.0 18.7 8.3e-05 22.5 0.0 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 VBB34200.1 - 3.4e-19 68.6 11.8 7e-06 25.9 0.0 5.7 4 1 2 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 VBB34200.1 - 1.5e-17 62.8 15.5 8.6e-05 22.4 0.0 5.9 5 2 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 VBB34200.1 - 1.9e-17 63.1 4.4 6.6e-05 23.1 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Patched PF02460.18 VBB34201.1 - 7.6e-32 110.3 5.7 8.7e-32 110.1 5.7 1.0 1 0 0 1 1 1 1 Patched family ECSCR PF15820.5 VBB34201.1 - 6.8 6.6 6.1 13 5.7 6.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Dicty_REP PF05086.12 VBB34202.1 - 0.0058 14.7 0.7 0.0065 14.5 0.7 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 VBB34202.1 - 0.071 13.1 12.4 0.1 12.6 12.3 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF4834 PF16118.5 VBB34202.1 - 0.15 13.1 0.0 0.19 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SSP160 PF06933.11 VBB34202.1 - 0.19 9.9 2.7 0.19 9.9 2.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 I-set PF07679.16 VBB34203.1 - 1.3e-18 66.8 0.0 2.7e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB34203.1 - 1.3e-18 67.3 3.4 8.5e-11 42.3 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 VBB34203.1 - 4e-11 43.1 0.0 7.4e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 VBB34203.1 - 7.4e-07 29.2 5.3 0.0046 17.0 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Dicty_REP PF05086.12 VBB34203.1 - 0.31 9.0 1.9 0.32 8.9 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 VBB34203.1 - 0.62 10.1 23.2 1.1 9.2 23.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 VBB34203.1 - 2.2 6.4 20.7 3 5.9 20.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 VBB34203.1 - 4.5 5.3 7.7 5.7 4.9 7.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PDZ PF00595.24 VBB34205.1 - 2.1e-08 34.4 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB34205.1 - 1.2e-05 25.0 0.2 2.5e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB34205.1 - 0.001 19.4 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain zf-CXXC PF02008.20 VBB34205.1 - 0.15 12.1 6.3 5 7.2 0.4 2.7 2 0 0 2 2 2 0 CXXC zinc finger domain DUF3725 PF12523.8 VBB34205.1 - 0.18 12.1 4.2 0.36 11.1 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) Homeobox_KN PF05920.11 VBB34206.1 - 0.0017 18.2 0.2 0.0017 18.2 0.2 2.5 2 1 0 2 2 1 1 Homeobox KN domain CDC45 PF02724.14 VBB34206.1 - 0.095 11.0 30.8 0.11 10.8 30.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 VBB34206.1 - 0.1 12.1 35.9 0.12 12.0 35.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MAP7 PF05672.11 VBB34206.1 - 0.16 11.7 56.6 0.19 11.4 56.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Presenilin PF01080.17 VBB34206.1 - 0.16 10.7 40.8 0.18 10.5 40.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 VBB34206.1 - 0.17 11.7 32.5 0.2 11.4 32.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 VBB34206.1 - 0.37 9.8 35.0 0.42 9.6 35.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4045 PF13254.6 VBB34206.1 - 0.4 10.3 28.5 0.44 10.2 28.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.6 VBB34206.1 - 0.49 10.4 26.2 0.62 10.0 26.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Nop53 PF07767.11 VBB34206.1 - 0.55 9.6 37.7 0.65 9.3 37.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hydin_ADK PF17213.3 VBB34206.1 - 0.89 9.8 25.8 1.1 9.5 25.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PAT1 PF09770.9 VBB34206.1 - 0.93 7.7 53.4 1.1 7.5 53.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 VBB34206.1 - 0.95 7.9 27.0 1 7.8 27.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF4569 PF15133.6 VBB34206.1 - 1 9.0 32.9 1.4 8.6 32.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) WTX PF09422.10 VBB34206.1 - 1.1 8.2 23.0 1.2 8.1 23.0 1.1 1 0 0 1 1 1 0 WTX protein AUX_IAA PF02309.16 VBB34206.1 - 1.4 8.7 21.6 1.6 8.5 21.6 1.3 1 0 0 1 1 1 0 AUX/IAA family GAGA_bind PF06217.12 VBB34206.1 - 1.6 9.0 27.7 1.8 8.8 27.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family NPR3 PF03666.13 VBB34206.1 - 1.7 7.3 31.7 1.9 7.2 31.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Smg8_Smg9 PF10220.9 VBB34206.1 - 2.5 6.3 30.4 2.5 6.3 30.4 1.0 1 0 0 1 1 1 0 Smg8_Smg9 CCSAP PF15748.5 VBB34206.1 - 2.5 8.2 38.3 2.9 8.0 38.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 VBB34206.1 - 2.7 7.5 30.4 3.2 7.3 30.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 VBB34206.1 - 2.8 6.7 24.8 3.1 6.6 24.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 VBB34206.1 - 2.9 6.6 29.5 3.6 6.3 29.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 VBB34206.1 - 3.1 4.8 35.6 3.5 4.6 35.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 VBB34206.1 - 3.2 7.1 18.7 4 6.8 18.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ALMT PF11744.8 VBB34206.1 - 4.2 6.1 29.1 5.1 5.8 29.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 VBB34206.1 - 4.5 5.3 34.7 5 5.1 34.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 VBB34206.1 - 4.6 6.6 30.9 6.5 6.1 30.9 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cellulose_synt PF03552.14 VBB34206.1 - 5.2 5.4 13.5 6.4 5.1 13.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Raftlin PF15250.6 VBB34206.1 - 5.4 5.6 27.9 6.3 5.4 27.9 1.1 1 0 0 1 1 1 0 Raftlin MRP-S26 PF14943.6 VBB34206.1 - 5.6 6.8 36.0 8.3 6.3 36.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 eIF3_subunit PF08597.10 VBB34206.1 - 5.9 6.7 33.7 8 6.3 33.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ten_N PF06484.12 VBB34206.1 - 6.4 6.5 22.6 7.1 6.4 22.6 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region AAA_11 PF13086.6 VBB34206.1 - 6.6 6.4 32.6 7.8 6.2 32.6 1.2 1 0 0 1 1 1 0 AAA domain CAC1F_C PF16885.5 VBB34206.1 - 6.9 6.2 24.5 9.9 5.7 24.5 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Myc_N PF01056.18 VBB34206.1 - 8.2 6.2 22.4 13 5.6 22.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region XRN_M PF17846.1 VBB34206.1 - 8.7 5.2 29.6 10 4.9 29.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF966 PF06136.13 VBB34206.1 - 9.8 5.8 25.6 11 5.6 25.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4739 PF15893.5 VBB34207.1 - 0.0074 15.9 0.1 0.0091 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4739) Tetraspanin PF00335.20 VBB34208.1 - 5.6e-14 52.4 3.9 7.5e-14 52.0 3.9 1.2 1 0 0 1 1 1 1 Tetraspanin family Shisa PF13908.6 VBB34208.1 - 0.012 15.8 0.4 0.012 15.8 0.4 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1729 PF08354.10 VBB34209.1 - 0.045 12.6 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) EGF_3 PF12947.7 VBB34211.1 - 2.1e-30 104.6 113.9 2.2e-07 30.9 7.7 10.8 9 2 1 10 10 10 7 EGF domain EGF_CA PF07645.15 VBB34211.1 - 6.3e-30 103.1 111.1 8.6e-08 32.3 4.7 10.6 9 2 1 10 10 10 7 Calcium-binding EGF domain EGF PF00008.27 VBB34211.1 - 1.8e-21 76.1 112.6 2.1e-05 24.7 5.1 11.6 10 1 0 10 10 10 7 EGF-like domain hEGF PF12661.7 VBB34211.1 - 9.3e-15 54.6 96.8 3.4e-05 24.3 0.7 12.9 12 0 0 12 12 12 8 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 VBB34211.1 - 2.8e-09 36.9 80.2 0.00023 21.1 7.6 8.8 9 0 0 9 9 9 5 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 VBB34211.1 - 7.4e-06 26.2 101.2 0.0021 18.3 7.5 8.6 9 0 0 9 9 9 6 Pvs28 EGF domain FXa_inhibition PF14670.6 VBB34211.1 - 8.5e-05 22.7 109.7 0.044 14.1 3.9 11.1 9 2 1 10 10 10 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB34211.1 - 0.0097 15.8 0.2 0.0097 15.8 0.2 11.2 12 0 0 12 12 12 6 Complement Clr-like EGF-like Trehalase PF01204.18 VBB34212.1 - 4.7e-130 434.8 1.8 5.5e-130 434.6 1.8 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 VBB34212.1 - 0.0074 15.1 1.1 0.7 8.6 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain GDE_C PF06202.14 VBB34212.1 - 0.023 13.6 0.3 0.12 11.3 0.3 2.1 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Ig_3 PF13927.6 VBB34213.1 - 1.7e-19 70.2 0.1 8.5e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 VBB34213.1 - 9.1e-19 67.3 0.0 2.7e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 VBB34213.1 - 3.7e-11 43.2 0.0 7.4e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 VBB34213.1 - 4.9e-09 36.2 0.4 1.6e-05 24.9 0.0 2.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 VBB34213.1 - 2.1e-07 30.9 1.3 0.0046 17.0 0.0 3.0 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Glyco_hydro_15 PF00723.21 VBB34214.1 - 1.4e-83 281.2 0.1 1.5e-83 281.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ras PF00071.22 VBB34215.1 - 2.1e-52 177.0 0.2 3.8e-52 176.2 0.2 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 VBB34215.1 - 1.7e-30 105.7 0.0 3.4e-30 104.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB34215.1 - 4.7e-13 49.0 0.1 9.4e-13 48.0 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 VBB34215.1 - 0.00026 21.0 0.0 0.00049 20.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 VBB34215.1 - 0.00029 20.8 0.1 0.033 14.1 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 VBB34215.1 - 0.0009 19.0 0.1 0.0012 18.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.12 VBB34215.1 - 0.0087 15.6 0.1 0.044 13.3 0.0 1.9 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 VBB34215.1 - 0.0099 16.3 0.0 0.028 14.8 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 VBB34215.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 VBB34215.1 - 0.011 15.4 0.1 0.032 14.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 VBB34215.1 - 0.016 14.6 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 VBB34215.1 - 0.034 13.6 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 VBB34215.1 - 0.065 13.8 0.1 0.13 12.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 VBB34215.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 VBB34215.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 VBB34215.1 - 0.15 11.9 0.4 1.7 8.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF3361 PF11841.8 VBB34216.1 - 1.2e-32 113.0 1.2 1.7e-32 112.5 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) SIL1 PF16782.5 VBB34216.1 - 0.0059 15.9 0.7 0.0098 15.1 0.7 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF3384 PF11864.8 VBB34216.1 - 0.027 13.4 0.3 0.037 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Band_3_cyto PF07565.13 VBB34218.1 - 1.6e-16 61.0 0.0 2.8e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DUF5641 PF18701.1 VBB34222.1 - 1.2e-06 28.6 1.1 0.00054 20.1 0.1 2.6 1 1 1 2 2 2 2 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 VBB34222.1 - 0.0073 16.4 0.1 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain UvrD_C PF13361.6 VBB34222.1 - 0.048 13.0 0.2 0.069 12.5 0.2 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Chromo PF00385.24 VBB34223.1 - 1.1e-10 41.3 0.1 2.9e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SOBP PF15279.6 VBB34223.1 - 0.33 11.5 3.2 0.61 10.6 0.1 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein CBM_14 PF01607.24 VBB34224.1 - 5.7e-13 48.8 4.2 9e-13 48.2 4.2 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Pep1_7 PF17232.2 VBB34224.1 - 4.5 7.8 7.4 5.4 7.6 0.5 2.5 1 1 0 2 2 2 0 Elicitor peptide 1-7 Ras PF00071.22 VBB34225.1 - 1.1e-53 181.2 0.0 1.3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 VBB34225.1 - 1.2e-36 125.6 0.0 1.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 VBB34225.1 - 3.2e-14 52.8 0.0 3.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 VBB34225.1 - 2.1e-07 30.5 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 VBB34225.1 - 2.1e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 VBB34225.1 - 1.6e-05 24.6 0.1 7.1e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 VBB34225.1 - 6.9e-05 22.4 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 VBB34225.1 - 0.0007 19.4 0.5 0.13 12.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein NACHT PF05729.12 VBB34225.1 - 0.01 15.7 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 VBB34225.1 - 0.011 15.6 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 VBB34225.1 - 0.012 16.1 0.1 0.018 15.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 VBB34225.1 - 0.016 15.2 0.1 0.034 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 VBB34225.1 - 0.021 15.2 0.0 0.053 13.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 VBB34225.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 VBB34225.1 - 0.027 14.5 0.1 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 VBB34225.1 - 0.044 13.5 0.1 0.19 11.5 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 VBB34225.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 VBB34225.1 - 0.061 13.6 0.4 0.23 11.7 0.2 2.0 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 VBB34225.1 - 0.062 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 VBB34225.1 - 0.18 12.3 0.1 0.39 11.2 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Annexin PF00191.20 VBB34227.1 - 1.7e-78 258.7 12.0 8.5e-24 83.4 0.1 4.0 4 0 0 4 4 4 4 Annexin Sialidase PF02973.16 VBB34227.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Sialidase, N-terminal domain Het-C PF07217.11 VBB34227.1 - 0.12 10.9 0.2 0.54 8.7 0.1 1.8 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF1187 PF06688.11 VBB34229.1 - 0.086 13.2 0.5 1.7 9.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1187) EF-hand_1 PF00036.32 VBB34230.1 - 1.1e-28 96.5 16.3 5.5e-08 31.8 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 VBB34230.1 - 1.1e-27 96.2 6.9 1.8e-14 53.9 1.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 VBB34230.1 - 5.4e-24 82.6 16.1 1.1e-06 27.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 VBB34230.1 - 1.8e-23 80.4 11.9 7.1e-07 28.7 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 VBB34230.1 - 4.3e-21 74.5 12.5 1.1e-07 31.6 1.4 3.4 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 VBB34230.1 - 6e-10 39.4 0.2 3.8e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 VBB34230.1 - 1.9e-07 31.0 7.4 0.00023 21.1 1.0 3.6 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 VBB34230.1 - 7.1e-07 30.1 0.3 0.0048 17.8 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 VBB34230.1 - 3.5e-06 26.9 0.0 0.095 12.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 VBB34230.1 - 0.00032 21.0 0.9 0.033 14.5 0.1 2.5 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 VBB34230.1 - 0.0062 16.5 0.9 6.1 6.8 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 VBB34230.1 - 0.0067 16.6 13.2 0.69 10.2 2.0 3.5 2 2 1 3 3 3 2 Dockerin type I domain HHA PF05321.11 VBB34230.1 - 0.1 12.9 0.1 2 8.8 0.1 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein Homeodomain PF00046.29 VBB34232.1 - 2.9e-21 75.1 7.9 4.9e-21 74.3 7.9 1.4 1 0 0 1 1 1 1 Homeodomain SatD PF16264.5 VBB34232.1 - 0.0019 17.9 0.2 0.0028 17.3 0.2 1.2 1 0 0 1 1 1 1 SatD family (SatD) Homeobox_KN PF05920.11 VBB34232.1 - 0.0063 16.4 0.3 0.017 15.0 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4460 PF14687.6 VBB34232.1 - 0.2 11.7 2.8 0.87 9.7 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4460) TIMELESS PF04821.14 VBB34232.1 - 8.5 5.6 7.9 17 4.6 0.2 2.0 2 0 0 2 2 2 0 Timeless protein CUB PF00431.20 VBB34233.1 - 2.6e-54 182.3 0.0 1.1e-23 83.6 0.0 3.4 3 0 0 3 3 3 3 CUB domain Sushi PF00084.20 VBB34233.1 - 6.5e-28 97.1 19.0 8.1e-07 29.6 0.4 5.1 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) EGF_CA PF07645.15 VBB34233.1 - 8.8e-10 38.6 5.5 8.8e-10 38.6 5.5 4.0 4 0 0 4 4 4 1 Calcium-binding EGF domain Ldl_recept_a PF00057.18 VBB34233.1 - 9.4e-08 32.2 8.0 9.4e-08 32.2 8.0 3.3 2 1 1 3 3 3 1 Low-density lipoprotein receptor domain class A HRM PF02793.22 VBB34233.1 - 5e-07 29.9 10.7 0.042 14.2 0.2 4.7 3 1 1 4 4 4 3 Hormone receptor domain CUB_2 PF02408.20 VBB34233.1 - 1.7e-06 27.8 0.6 0.024 14.4 0.0 3.7 3 0 0 3 3 3 2 CUB-like domain F5_F8_type_C PF00754.25 VBB34233.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain cEGF PF12662.7 VBB34233.1 - 0.071 13.1 0.4 0.071 13.1 0.4 6.3 6 0 0 6 6 6 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 VBB34233.1 - 0.57 10.5 12.3 0.38 11.1 7.3 3.3 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Glyco_hydro_47 PF01532.20 VBB34234.1 - 3.6e-48 164.6 0.0 5.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M24 PF00557.24 VBB34235.1 - 2.6e-21 76.3 0.1 3.2e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Herpes_glycop PF01528.16 VBB34236.1 - 0.0034 16.3 0.2 0.0047 15.8 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus glycoprotein M DUF4381 PF14316.6 VBB34236.1 - 0.038 14.2 1.5 0.043 14.1 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) HemY_N PF07219.13 VBB34236.1 - 0.059 13.6 1.3 0.12 12.5 1.3 1.5 1 0 0 1 1 1 0 HemY protein N-terminus LST1 PF05083.13 VBB34236.1 - 0.13 12.6 1.9 0.71 10.2 0.4 2.5 2 0 0 2 2 2 0 LST-1 protein Cadherin_C_2 PF16492.5 VBB34236.1 - 0.3 11.8 0.1 0.3 11.8 0.1 2.4 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 VBB34236.1 - 0.31 11.9 2.7 0.39 11.6 0.2 2.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4735 PF15882.5 VBB34238.1 - 5.8e-70 236.0 0.1 7e-70 235.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) LSM PF01423.22 VBB34239.1 - 5.8e-20 70.7 0.0 8.3e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Mito_fiss_reg PF05308.11 VBB34240.1 - 0.023 14.8 0.3 0.023 14.8 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 VBB34240.1 - 2.6 7.4 8.0 3.6 7.0 8.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 VBB34241.1 - 0.19 11.8 3.9 0.2 11.7 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 VBB34241.1 - 1.3 9.1 8.8 1.5 8.9 8.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyoxalase PF00903.25 VBB34243.1 - 5.8e-18 65.3 0.0 8.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 VBB34243.1 - 6.1e-06 26.5 0.0 2.7e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 VBB34243.1 - 0.001 19.8 0.0 0.0026 18.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain DUF411 PF04214.13 VBB34243.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF TIP49 PF06068.13 VBB34244.1 - 4.6e-88 295.8 4.1 5.2e-88 295.6 4.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 VBB34244.1 - 9e-08 32.6 0.2 1.4e-07 32.0 0.2 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB34244.1 - 2.7e-06 27.9 0.0 3.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 VBB34244.1 - 3.1e-05 24.0 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 VBB34244.1 - 4.4e-05 23.0 0.6 5.3e-05 22.7 0.6 1.2 1 0 0 1 1 1 1 KaiC RuvB_N PF05496.12 VBB34244.1 - 9.9e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 VBB34244.1 - 0.00016 21.1 0.3 0.00024 20.5 0.3 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 VBB34244.1 - 0.00016 21.0 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 VBB34244.1 - 0.00033 20.1 0.1 0.00041 19.8 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_7 PF12775.7 VBB34244.1 - 0.00038 20.0 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 VBB34244.1 - 0.00062 19.5 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 VBB34244.1 - 0.0014 18.9 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 VBB34244.1 - 0.0022 17.6 0.2 0.0027 17.3 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 VBB34244.1 - 0.0027 18.0 0.2 0.0041 17.4 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 VBB34244.1 - 0.0028 18.2 0.1 0.0033 17.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 VBB34244.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain KTI12 PF08433.10 VBB34244.1 - 0.0031 17.0 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 VBB34244.1 - 0.0033 17.2 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 VBB34244.1 - 0.0042 16.4 0.1 0.0069 15.7 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 VBB34244.1 - 0.0077 16.8 0.1 0.02 15.5 0.1 1.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 VBB34244.1 - 0.0082 16.5 0.4 0.014 15.8 0.4 1.4 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 VBB34244.1 - 0.011 15.7 0.2 0.024 14.6 0.1 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 VBB34244.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 VBB34244.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 VBB34244.1 - 0.015 15.1 0.5 0.019 14.7 0.5 1.4 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 VBB34244.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.12 VBB34244.1 - 0.025 14.4 0.1 0.054 13.3 0.1 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 VBB34244.1 - 0.027 13.9 0.9 0.13 11.7 0.1 2.2 2 1 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 VBB34244.1 - 0.034 14.0 0.2 0.096 12.6 0.2 2.0 1 1 0 1 1 1 0 NTPase AAA_17 PF13207.6 VBB34244.1 - 0.037 14.5 0.1 0.062 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 VBB34244.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 VBB34244.1 - 0.058 13.8 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 VBB34244.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain RHS_repeat PF05593.14 VBB34244.1 - 0.13 12.8 0.1 0.43 11.1 0.0 1.9 2 0 0 2 2 1 0 RHS Repeat AAA_29 PF13555.6 VBB34244.1 - 0.15 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bromodomain PF00439.25 VBB34245.1 - 2.5e-11 43.5 0.0 4.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain PDZ_6 PF17820.1 VBB34247.1 - 1.6e-14 53.5 0.0 1.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 VBB34247.1 - 6.7e-13 48.8 0.0 2.9e-05 24.3 0.0 2.5 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 VBB34247.1 - 3.6e-12 46.5 0.0 7.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 VBB34247.1 - 0.00038 20.8 0.0 0.067 13.6 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 VBB34247.1 - 0.06 13.3 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Tricorn protease PDZ domain COesterase PF00135.28 VBB34248.1 - 1.2e-08 34.3 0.1 1.2e-08 34.3 0.1 1.6 2 0 0 2 2 2 1 Carboxylesterase family TMEM51 PF15345.6 VBB34248.1 - 0.031 14.1 0.4 0.065 13.1 0.4 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 Adeno_E3_CR2 PF02439.15 VBB34248.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 eIF-6 PF01912.18 VBB34250.1 - 0.075 12.4 0.0 0.081 12.3 0.0 1.0 1 0 0 1 1 1 0 eIF-6 family WSC PF01822.19 VBB34251.1 - 1.4e-14 54.0 4.3 1.4e-14 54.0 4.3 1.6 2 0 0 2 2 2 1 WSC domain HEAT PF02985.22 VBB34252.1 - 7.2e-08 32.1 4.6 2.1 8.8 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 VBB34252.1 - 8.8e-05 22.8 0.1 0.074 13.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 VBB34252.1 - 0.00033 20.7 4.3 0.055 13.5 0.2 2.5 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 VBB34252.1 - 0.0033 17.6 0.7 0.042 14.0 0.3 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 VBB34252.1 - 0.0037 15.9 4.1 0.029 12.9 3.5 2.8 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.13 VBB34252.1 - 0.011 15.2 3.6 0.26 10.7 0.1 2.7 3 0 0 3 3 3 0 Armadillo-like Xpo1 PF08389.12 VBB34252.1 - 0.32 11.1 4.9 0.39 10.8 0.1 2.9 3 0 0 3 3 3 0 Exportin 1-like protein Cation_efflux PF01545.21 VBB34253.1 - 1.3e-46 158.8 25.1 1.6e-46 158.5 25.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 VBB34253.1 - 0.03 14.5 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter MCU PF04678.13 VBB34253.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter 7tm_1 PF00001.21 VBB34253.1 - 1.7 7.9 13.6 2.8 7.2 2.2 2.6 1 1 2 3 3 3 0 7 transmembrane receptor (rhodopsin family) DUF4551 PF15087.6 VBB34254.1 - 1.8 7.3 8.0 2.1 7.1 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CREPT PF16566.5 VBB34254.1 - 2 8.6 7.2 1.2 9.4 2.0 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Trypsin PF00089.26 VBB34255.1 - 2e-21 76.9 0.1 6.9e-20 71.8 0.1 2.8 1 1 1 2 2 2 1 Trypsin Adaptin_N PF01602.20 VBB34255.1 - 1.3e-19 70.2 0.0 2.3e-16 59.5 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region DUF316 PF03761.15 VBB34255.1 - 8.6e-11 41.9 0.1 2e-07 30.9 0.0 3.1 3 0 0 3 3 3 2 Chymotrypsin family Peptidase-S1 Cnd1 PF12717.7 VBB34255.1 - 0.0045 17.1 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 MSL1_dimer PF16801.5 VBB34256.1 - 0.13 12.1 1.1 0.26 11.1 1.1 1.5 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 DUF19 PF01579.18 VBB34257.1 - 1.1e-05 25.3 6.3 6.6e-05 22.8 5.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF19) Y_phosphatase PF00102.27 VBB34258.1 - 2.1e-24 86.4 0.0 2.3e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB34258.1 - 1.4e-06 28.1 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB34258.1 - 0.00036 20.6 0.0 0.0004 20.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 VBB34258.1 - 0.031 13.2 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 VBB34258.1 - 0.048 13.8 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate bZIP_1 PF00170.21 VBB34259.1 - 2.7e-15 56.2 12.9 8.6e-15 54.6 12.9 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 VBB34259.1 - 2.5e-08 33.9 11.4 1e-07 31.9 11.4 2.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 VBB34259.1 - 1.2e-05 25.7 10.5 1.2e-05 25.7 10.5 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor DivIC PF04977.15 VBB34259.1 - 0.018 14.8 2.6 0.085 12.6 2.6 2.2 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 VBB34259.1 - 0.057 13.7 1.7 0.15 12.3 1.7 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 VBB34259.1 - 0.085 12.4 6.2 0.3 10.6 5.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 AKNA PF12443.8 VBB34259.1 - 0.58 10.8 4.5 0.73 10.5 2.0 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF3450 PF11932.8 VBB34259.1 - 0.64 9.3 6.1 0.26 10.5 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 VBB34259.1 - 4.5 7.8 13.3 0.43 11.1 6.1 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Gelsolin PF00626.22 VBB34260.1 - 7.3e-12 45.0 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Gelsolin repeat fn3 PF00041.21 VBB34261.1 - 5e-07 30.0 0.0 8.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Ank_2 PF12796.7 VBB34261.1 - 0.0084 16.7 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) HIM1 PF08732.10 VBB34261.1 - 0.05 13.1 0.2 0.074 12.6 0.2 1.2 1 0 0 1 1 1 0 HIM1 Ank_4 PF13637.6 VBB34261.1 - 0.074 13.7 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RasGEF PF00617.19 VBB34262.1 - 1.7e-43 148.8 4.1 2.2e-43 148.5 1.2 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 VBB34262.1 - 1.6e-11 44.3 0.5 3.9e-11 43.1 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif LETM1 PF07766.13 VBB34263.1 - 1.3e-24 87.0 9.4 8.4e-18 64.7 1.9 2.1 1 1 1 2 2 2 2 LETM1-like protein OHA PF14418.6 VBB34263.1 - 0.022 14.5 0.2 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain ExoD PF06055.12 VBB34263.1 - 0.034 13.5 0.4 0.12 11.7 0.2 1.9 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD FANCI_HD2 PF14680.6 VBB34265.1 - 0.056 12.7 0.3 0.13 11.4 0.1 1.6 1 1 1 2 2 2 0 FANCI helical domain 2 BUD22 PF09073.10 VBB34265.1 - 1.2 8.4 16.5 1.6 8.0 16.5 1.1 1 0 0 1 1 1 0 BUD22 GCIP PF13324.6 VBB34265.1 - 1.5 8.4 19.8 1.2 8.7 6.3 2.1 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting RRM_5 PF13893.6 VBB34267.1 - 1.5e-09 37.5 0.1 2.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 VBB34267.1 - 2.6e-05 24.0 0.0 9.4e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 VBB34267.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF3855 PF12967.7 VBB34267.1 - 0.035 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) Gemini_AL1_M PF08283.11 VBB34267.1 - 0.045 13.8 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain CUE PF02845.16 VBB34267.1 - 0.062 13.0 0.0 0.35 10.6 0.1 2.1 2 0 0 2 2 2 0 CUE domain Cnn_1N PF07989.11 VBB34272.1 - 0.00096 19.3 13.0 0.0045 17.1 1.8 3.0 2 1 1 3 3 3 2 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 VBB34272.1 - 0.061 13.3 24.8 0.94 9.5 3.4 4.1 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 VBB34272.1 - 0.19 11.9 17.7 0.14 12.3 1.6 4.0 3 1 0 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 VBB34272.1 - 0.2 11.8 7.4 1.9 8.6 0.1 3.7 3 1 1 4 4 4 0 bZIP transcription factor TSC22 PF01166.18 VBB34272.1 - 0.75 10.1 10.9 1.1 9.7 0.1 3.8 4 2 0 4 4 4 0 TSC-22/dip/bun family Csm1_N PF18504.1 VBB34272.1 - 1.2 9.5 12.8 0.14 12.5 0.8 3.6 2 1 1 3 3 3 0 Csm1 N-terminal domain ZapB PF06005.12 VBB34272.1 - 1.9 9.0 22.0 3.4 8.2 1.6 4.2 2 1 2 4 4 4 0 Cell division protein ZapB YabA PF06156.13 VBB34272.1 - 5 7.8 11.9 8.8 7.0 0.9 3.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4738 PF15889.5 VBB34273.1 - 0.011 15.6 0.3 0.016 15.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4738) AcetylCoA_hyd_C PF13336.6 VBB34274.1 - 7.4e-58 194.9 0.0 1.2e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 VBB34274.1 - 9.8e-20 71.4 0.0 1.9e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain UCH PF00443.29 VBB34275.1 - 7.6e-13 48.5 1.2 9.8e-13 48.2 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB34275.1 - 0.052 13.1 3.8 0.47 10.0 3.8 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CD20 PF04103.15 VBB34276.1 - 2.1e-08 34.4 10.6 3.1e-08 33.9 10.6 1.3 1 0 0 1 1 1 1 CD20-like family DUF2101 PF09874.9 VBB34276.1 - 0.2 11.3 1.7 0.27 10.9 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) CENP-F_leu_zip PF10473.9 VBB34277.1 - 0.00031 20.8 92.0 0.0047 17.0 6.1 6.5 1 1 5 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 VBB34277.1 - 0.0027 17.7 22.3 0.0027 17.7 22.3 5.6 2 2 2 4 4 3 2 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 VBB34277.1 - 0.0076 15.9 34.0 0.0076 15.9 34.0 4.9 1 1 4 5 5 5 3 Ciliary protein causing Leber congenital amaurosis disease APC_N_CC PF16689.5 VBB34277.1 - 0.032 14.3 1.3 0.032 14.3 1.3 6.7 6 1 1 7 7 7 0 Coiled-coil N-terminus of APC, dimerisation domain APG6_N PF17675.1 VBB34277.1 - 0.032 14.8 101.0 0.13 12.8 17.7 5.9 1 1 5 6 6 6 0 Apg6 coiled-coil region ERM PF00769.19 VBB34277.1 - 0.042 13.7 105.6 0.033 14.0 21.6 4.7 1 1 3 4 4 4 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 VBB34277.1 - 0.35 10.9 54.7 0.042 13.9 3.2 6.2 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 VBB34277.1 - 0.69 10.1 95.3 0.16 12.2 25.5 5.4 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 VBB34277.1 - 1.1 7.3 87.5 0.46 8.6 9.4 3.3 1 1 2 3 3 3 0 HOOK protein DUF3800 PF12686.7 VBB34277.1 - 1.3 9.7 4.9 1.2e+02 3.3 5.2 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Tropomyosin_1 PF12718.7 VBB34277.1 - 1.4 9.0 88.6 2.3 8.4 20.2 5.1 1 1 2 4 4 4 0 Tropomyosin like Tropomyosin PF00261.20 VBB34277.1 - 3.9 6.8 86.9 0.087 12.2 21.4 4.3 1 1 3 4 4 4 0 Tropomyosin Uso1_p115_C PF04871.13 VBB34277.1 - 5.6 7.3 83.1 4.1 7.8 10.4 5.7 1 1 5 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region PI3_PI4_kinase PF00454.27 VBB34278.1 - 2.8e-13 50.3 0.0 3.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TFIID_20kDa PF03847.13 VBB34279.1 - 6.7e-18 65.0 2.6 1.1e-17 64.3 2.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 VBB34279.1 - 0.00052 20.1 0.1 0.00052 20.1 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 VBB34279.1 - 0.0012 18.8 0.3 0.0035 17.3 0.3 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 VBB34279.1 - 0.0014 18.9 0.4 0.0031 17.8 0.4 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RCDG1 PF15725.5 VBB34279.1 - 0.014 15.8 1.8 0.02 15.3 0.1 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Zip PF02535.22 VBB34279.1 - 3.2 6.9 8.9 4.5 6.4 8.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 VBB34279.1 - 4.6 6.7 8.2 7.8 5.9 8.2 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 MecA PF05389.12 VBB34279.1 - 7.4 6.1 18.9 1.8 8.2 15.3 1.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FAM60A PF15396.6 VBB34279.1 - 8.8 6.3 11.1 19 5.2 11.1 1.7 1 0 0 1 1 1 0 Protein Family FAM60A zf-H2C2_2 PF13465.6 VBB34280.1 - 1.4e-20 72.7 42.5 9.8e-07 28.9 0.3 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 VBB34280.1 - 1e-15 57.2 59.8 0.00034 20.9 3.8 7.6 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB34280.1 - 1.9e-13 50.0 66.3 0.0015 19.2 1.5 8.1 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB34280.1 - 7.5e-08 32.5 35.2 0.017 15.4 1.9 7.6 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 VBB34280.1 - 1.6e-05 25.1 31.0 8.4e-05 22.8 4.1 5.3 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 VBB34280.1 - 0.021 14.6 34.0 0.88 9.4 0.5 6.4 6 0 0 6 6 6 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 VBB34280.1 - 0.021 15.1 10.6 1.9 8.8 0.1 5.1 5 0 0 5 5 5 0 zinc-ribbon zf-met PF12874.7 VBB34280.1 - 0.025 14.9 0.5 0.025 14.9 0.5 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 VBB34280.1 - 0.043 13.4 0.1 0.043 13.4 0.1 6.6 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 VBB34280.1 - 0.045 13.8 1.9 27 4.9 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger domain TerY_C PF15616.6 VBB34280.1 - 0.083 13.0 0.1 0.083 13.0 0.1 2.9 2 1 0 3 3 2 0 TerY-C metal binding domain zf-C2HC_2 PF13913.6 VBB34280.1 - 0.1 12.6 0.3 0.1 12.6 0.3 5.2 6 0 0 6 6 4 0 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.6 VBB34280.1 - 0.2 11.1 5.8 2.2 7.8 0.1 4.2 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 VBB34280.1 - 0.27 10.8 5.3 5.3 6.6 0.2 3.8 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 VBB34280.1 - 2.3 8.2 15.6 0.92 9.5 0.5 3.7 3 1 0 3 3 2 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 VBB34280.1 - 5.5 7.8 25.4 0.67 10.7 4.0 5.4 4 1 1 5 5 5 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 VBB34280.1 - 7.2 6.8 27.1 0.53 10.4 2.6 5.7 3 1 3 6 6 6 0 Zinc ribbon domain FYVE PF01363.21 VBB34280.1 - 9 6.5 33.1 0.51 10.5 3.7 5.0 3 2 1 4 4 4 0 FYVE zinc finger Collagen PF01391.18 VBB34281.1 - 1.4e-10 40.8 44.7 1.9e-08 33.9 44.7 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) CUB PF00431.20 VBB34282.1 - 2.7e-11 43.8 0.0 1.9e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 CUB domain SCIMP PF15050.6 VBB34282.1 - 0.2 12.1 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein Env-gp36 PF09590.10 VBB34284.1 - 0.021 13.3 0.1 0.023 13.2 0.1 1.0 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Orf78 PF06024.12 VBB34284.1 - 0.043 14.1 0.1 0.047 14.0 0.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF5527 PF17665.1 VBB34284.1 - 0.062 12.8 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Baculo_11_kDa PF06143.11 VBB34284.1 - 0.32 10.6 3.3 0.51 9.9 3.3 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1759 PF03564.15 VBB34285.1 - 1.7e-06 28.0 0.1 4.9e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1759) TPKR_C2 PF16920.5 VBB34285.1 - 0.036 14.2 0.9 0.12 12.5 0.9 2.0 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain Pkinase_Tyr PF07714.17 VBB34287.1 - 2.2e-11 43.5 0.0 1.4e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB34287.1 - 5.6e-11 42.3 0.0 1.2e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 VBB34287.1 - 1.5e-05 24.0 0.0 1.5e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 VBB34287.1 - 0.0011 18.4 0.1 0.0068 15.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB34287.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hyccin PF09790.9 VBB34289.1 - 3e-80 269.7 0.1 4.1e-80 269.3 0.1 1.1 1 0 0 1 1 1 1 Hyccin PP2C PF00481.21 VBB34290.1 - 2e-54 185.0 0.1 2.7e-54 184.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Calsequestrin PF01216.17 VBB34291.1 - 9.4e-61 206.0 13.6 1.2e-60 205.6 13.6 1.0 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 VBB34291.1 - 1.4e-13 51.1 0.6 2.1e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 VBB34291.1 - 0.15 12.1 2.3 5.8 7.0 0.0 3.3 4 1 0 4 4 4 0 Thioredoxin Patched PF02460.18 VBB34292.1 - 3e-101 339.9 3.4 3.4e-101 339.7 3.4 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB34292.1 - 3.2e-42 144.0 3.0 6.7e-42 142.9 3.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 VBB34292.1 - 5e-05 22.4 1.2 0.00012 21.2 1.2 1.5 1 1 0 1 1 1 1 MMPL family DUF535 PF04393.13 VBB34292.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Astacin PF01400.24 VBB34294.1 - 2.2e-19 69.9 0.0 5.2e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 VBB34294.1 - 1.8e-08 34.8 30.8 0.00079 19.9 2.8 3.6 3 0 0 3 3 3 3 ShK domain-like DUF1877 PF08974.10 VBB34294.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) SOG2 PF10428.9 VBB34294.1 - 0.17 11.1 15.6 0.014 14.6 10.9 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Podoplanin PF05808.11 VBB34294.1 - 1.7 8.7 19.2 3.3 7.8 19.2 1.4 1 0 0 1 1 1 0 Podoplanin Tudor_FRX1 PF18336.1 VBB34295.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain COesterase PF00135.28 VBB34296.1 - 7.3e-86 289.1 0.0 8.1e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB34296.1 - 1.5e-11 44.6 0.7 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 VBB34296.1 - 0.019 15.6 0.2 0.036 14.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 VBB34296.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 VBB34296.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_2 PF12796.7 VBB34297.1 - 5.7e-42 142.2 11.3 4.9e-13 49.5 0.1 4.9 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB34297.1 - 6.1e-36 122.3 9.2 4.6e-08 33.5 0.2 6.7 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB34297.1 - 8.7e-28 96.0 1.0 1.5e-10 41.1 0.1 5.9 3 3 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB34297.1 - 3.8e-24 82.1 2.8 0.00036 20.7 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 VBB34297.1 - 1.6e-20 72.6 7.3 4.4e-06 26.9 0.1 8.0 8 0 0 8 8 8 5 Ankyrin repeat GATase_7 PF13537.6 VBB34297.1 - 6.8e-06 26.0 0.0 2.2 8.2 0.0 4.0 2 1 2 4 4 4 3 Glutamine amidotransferase domain Cytochrom_B562 PF07361.11 VBB34297.1 - 0.00015 22.3 0.1 2.7 8.7 0.0 3.6 3 0 0 3 3 3 2 Cytochrome b562 DUF1843 PF08898.10 VBB34297.1 - 0.0064 17.0 2.1 11 6.7 0.0 4.4 4 1 0 4 4 4 2 Domain of unknown function (DUF1843) SnoaL_3 PF13474.6 VBB34297.1 - 0.013 15.8 0.0 6.5 7.1 0.0 2.6 2 0 0 2 2 2 0 SnoaL-like domain Y_phosphatase PF00102.27 VBB34298.1 - 4.4e-39 134.4 0.1 7.7e-37 127.1 0.0 2.1 1 1 0 2 2 2 2 Protein-tyrosine phosphatase FANCI_S2 PF14676.6 VBB34298.1 - 0.17 12.2 0.5 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 FANCI solenoid 2 RPAP3_C PF13877.6 VBB34299.1 - 6e-11 42.7 0.0 9.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 CRAL_TRIO PF00650.20 VBB34299.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain DUF3231 PF11553.8 VBB34299.1 - 0.086 12.5 0.2 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) DUF4600 PF15372.6 VBB34300.1 - 0.061 13.8 1.5 1 9.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Microvir_H PF04687.12 VBB34300.1 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) EF-hand_13 PF17958.1 VBB34301.1 - 1.5e-27 95.2 1.1 3.3e-26 90.9 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 VBB34301.1 - 9.7e-15 54.8 2.4 9.2e-14 51.7 0.1 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB34301.1 - 7e-09 34.9 0.6 0.00042 20.0 0.0 4.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 VBB34301.1 - 8.9e-09 34.3 3.0 4.1e-05 22.8 0.4 4.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 VBB34301.1 - 1.1e-07 31.0 2.3 6e-07 28.7 0.1 3.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 VBB34301.1 - 0.0041 16.9 1.4 0.023 14.6 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair PDEase_II PF02112.15 VBB34301.1 - 0.014 14.5 0.5 0.15 11.1 0.1 2.3 2 1 0 2 2 2 0 cAMP phosphodiesterases class-II Vitellogenin_N PF01347.22 VBB34302.1 - 0.0003 19.3 1.5 0.00038 19.0 1.5 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region Ion_trans PF00520.31 VBB34303.1 - 4.5e-33 114.5 19.2 5.5e-33 114.2 19.2 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 VBB34303.1 - 0.022 13.5 18.9 0.43 9.2 3.6 3.2 3 0 0 3 3 3 0 Polycystin cation channel TFIIA PF03153.13 VBB34303.1 - 3.9 7.4 34.1 8.4 6.3 34.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.6 VBB34304.1 - 5e-13 49.1 10.9 7.6e-13 48.6 10.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 VBB34304.1 - 3.3e-10 40.1 7.7 6.5e-10 39.2 7.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 VBB34304.1 - 3.6e-07 29.9 9.9 5.5e-07 29.3 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 VBB34304.1 - 5.5e-07 29.2 9.1 5.5e-07 29.2 9.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 VBB34304.1 - 2e-06 27.6 10.6 3.2e-06 26.9 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 VBB34304.1 - 2.9e-06 27.1 8.8 4.2e-06 26.6 8.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 VBB34304.1 - 2.3e-05 24.3 7.0 4.9e-05 23.3 7.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 VBB34304.1 - 2.4e-05 24.1 9.2 3.8e-05 23.5 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 VBB34304.1 - 0.00015 21.7 6.6 0.00037 20.5 6.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 VBB34304.1 - 0.00038 20.3 8.1 0.00064 19.5 8.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 VBB34304.1 - 0.072 12.7 7.4 0.12 12.0 7.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 VBB34304.1 - 0.47 10.6 10.1 0.85 9.8 10.1 1.4 1 0 0 1 1 1 0 RING-variant domain Vps39_2 PF10367.9 VBB34304.1 - 1.2 9.6 4.4 0.56 10.7 1.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.6 VBB34304.1 - 2.6 8.1 10.4 12 5.9 4.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 VBB34304.1 - 2.7 8.2 8.7 8.8 6.6 8.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 VBB34304.1 - 2.8 8.2 6.0 7.7 6.8 6.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 VBB34304.1 - 3.4 7.5 9.2 11 5.9 9.3 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain GTP_EFTU PF00009.27 VBB34305.1 - 2.8e-58 196.7 0.1 4.7e-58 195.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 VBB34305.1 - 6.5e-24 83.8 0.0 1.5e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 VBB34305.1 - 1.7e-10 40.8 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 VBB34305.1 - 5.7e-05 23.2 0.1 0.00014 21.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 VBB34305.1 - 0.0028 18.0 0.0 0.0085 16.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 VBB34305.1 - 0.0094 15.5 0.2 0.22 11.1 0.0 3.2 3 1 0 3 3 3 1 Ferrous iron transport protein B SRPRB PF09439.10 VBB34305.1 - 0.071 12.5 0.2 0.35 10.3 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3037 PF11236.8 VBB34305.1 - 0.087 13.3 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) AIG1 PF04548.16 VBB34305.1 - 0.091 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 AIG1 family TIP49 PF06068.13 VBB34306.1 - 5.6e-58 196.8 0.0 7.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 VBB34306.1 - 5.5e-20 71.3 0.2 1.2e-19 70.2 0.1 1.6 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA_22 PF13401.6 VBB34306.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain INT_SG_DDX_CT_C PF15300.6 VBB34307.1 - 0.04 13.7 1.0 0.04 13.7 1.0 2.1 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Kinesin PF00225.23 VBB34308.1 - 6.3e-75 252.2 1.6 1.4e-74 251.0 1.6 1.6 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 VBB34308.1 - 0.0053 16.9 11.9 0.015 15.5 8.9 2.8 2 1 0 2 2 2 1 Kinesin-associated DivIC PF04977.15 VBB34308.1 - 0.025 14.3 0.4 0.025 14.3 0.4 5.1 5 1 0 5 5 5 0 Septum formation initiator Thioredoxin_10 PF17991.1 VBB34308.1 - 0.17 12.4 2.1 0.46 11.0 2.1 1.8 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain PYNP_C PF07831.13 VBB34308.1 - 0.2 11.3 0.5 0.67 9.6 0.1 2.1 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Fib_alpha PF08702.10 VBB34308.1 - 9.8 6.4 27.2 0.074 13.2 6.1 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Pou PF00157.17 VBB34309.1 - 8.6e-31 105.7 0.1 8.2e-26 89.8 0.0 2.5 2 0 0 2 2 2 2 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 VBB34309.1 - 3.9e-17 61.8 0.1 1e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 Homeodomain HTH_ABP1_N PF18107.1 VBB34309.1 - 0.032 13.9 0.1 5.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Ins145_P3_rec PF08709.11 VBB34309.1 - 0.043 13.0 0.1 0.082 12.1 0.1 1.4 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF4157 PF13699.6 VBB34309.1 - 0.083 13.1 0.2 9.9 6.5 0.0 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4157) Metallophos PF00149.28 VBB34310.1 - 2.6e-23 83.6 0.2 5e-23 82.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 VBB34311.1 - 2.1e-06 26.8 1.9 0.22 11.2 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 VBB34311.1 - 9.1e-06 24.9 0.3 0.54 9.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 VBB34311.1 - 5.9e-05 22.7 2.1 0.45 10.6 0.0 3.9 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 VBB34311.1 - 0.0053 17.2 7.2 5.6 7.5 0.0 4.0 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 VBB34311.1 - 0.01 15.7 0.3 8 6.4 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain pair TGFb_propeptide PF00688.18 VBB34311.1 - 0.028 14.1 0.8 0.036 13.8 0.8 1.1 1 0 0 1 1 1 0 TGF-beta propeptide fn3_3 PF14686.6 VBB34311.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II OTU PF02338.19 VBB34312.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease Sema PF01403.19 VBB34313.1 - 8.7e-54 182.9 0.0 9.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Sema domain Cation_efflux PF01545.21 VBB34314.1 - 7e-21 74.9 0.1 8.8e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family RR_TM4-6 PF06459.12 VBB34316.1 - 2.2 8.0 18.4 5.6 6.7 18.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.18 VBB34316.1 - 2.9 6.7 21.1 5.3 5.8 21.1 1.4 1 0 0 1 1 1 0 Hsp90 protein CPSF100_C PF13299.6 VBB34316.1 - 3.6 7.7 14.4 0.48 10.6 10.2 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 VBB34316.1 - 5.4 6.7 8.8 12 5.6 8.8 1.5 1 0 0 1 1 1 0 Connexin Zip PF02535.22 VBB34316.1 - 5.9 6.0 5.8 7.5 5.7 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 VBB34316.1 - 9.5 5.1 10.0 17 4.2 10.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tcf25 PF04910.14 VBB34317.1 - 4.8e-56 190.3 3.8 7.4e-56 189.7 3.8 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Rap_GAP PF02145.15 VBB34318.1 - 0.0014 18.2 1.6 0.002 17.7 0.2 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Innexin PF00876.18 VBB34320.1 - 3.8e-74 250.1 14.5 7.2e-69 232.7 13.7 2.1 1 1 1 2 2 2 2 Innexin gerPA PF10676.9 VBB34321.1 - 0.025 14.8 2.3 0.046 14.0 2.3 1.6 1 1 0 1 1 1 0 Spore germination protein gerPA/gerPF Voltage_CLC PF00654.20 VBB34321.1 - 0.057 12.6 4.0 0.073 12.3 4.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel His_Me_b4a2 PF18275.1 VBB34322.1 - 0.019 15.0 0.1 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain Integrase_H2C2 PF17921.1 VBB34323.1 - 3e-06 27.2 0.9 5e-06 26.5 0.9 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain CTK3_C PF12350.8 VBB34323.1 - 0.37 11.0 3.0 0.44 10.7 0.1 2.4 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 C-terminus UCH PF00443.29 VBB34325.1 - 7.9e-15 55.0 3.0 1.3e-14 54.3 3.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 VBB34325.1 - 0.012 15.2 7.1 0.095 12.3 7.1 2.0 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PDZ PF00595.24 VBB34327.1 - 1.9e-31 108.3 0.0 2.2e-11 44.0 0.0 3.1 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 VBB34327.1 - 6.6e-19 67.5 0.0 4.8e-06 26.3 0.0 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 VBB34327.1 - 1.3e-08 35.1 0.0 4.2e-05 23.8 0.0 3.1 3 0 0 3 3 3 2 PDZ domain GRASP55_65 PF04495.14 VBB34327.1 - 0.028 14.8 0.0 0.15 12.4 0.0 2.0 1 1 1 2 2 2 0 GRASP55/65 PDZ-like domain CT_A_B PF02626.15 VBB34327.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B BROMI PF14961.6 VBB34327.1 - 0.2 9.1 0.0 0.27 8.6 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein YTH PF04146.15 VBB34328.1 - 1.1e-20 74.3 0.2 3e-17 63.1 0.0 2.9 2 1 0 2 2 2 1 YT521-B-like domain Cation_efflux PF01545.21 VBB34329.1 - 7.3e-25 87.9 12.9 9.4e-25 87.5 12.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 VBB34329.1 - 6.7e-12 45.4 0.9 1.3e-11 44.4 0.9 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1129 PF06570.11 VBB34329.1 - 0.0017 17.9 0.9 0.0031 17.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Dpy19 PF10034.9 VBB34330.1 - 2.8e-102 343.0 5.2 3.7e-102 342.6 5.2 1.2 1 0 0 1 1 1 1 Q-cell neuroblast polarisation HPIH PF13323.6 VBB34330.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain with HPIH motif Aldo_ket_red PF00248.21 VBB34331.1 - 3.8e-44 151.0 0.0 8.4e-44 149.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family UFD1 PF03152.14 VBB34332.1 - 4.1e-66 221.7 0.0 6.1e-66 221.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 VBB34332.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Neur_chan_LBD PF02931.23 VBB34336.1 - 2.9e-38 131.5 0.4 3.8e-38 131.1 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB34336.1 - 1.3e-19 71.2 1.6 2e-19 70.6 1.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Med26 PF08711.11 VBB34338.1 - 7.9e-13 48.2 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PA PF02225.22 VBB34338.1 - 0.0075 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Carb_anhydrase PF00194.21 VBB34339.1 - 2.9e-09 36.8 0.0 3.3e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.7 VBB34341.1 - 9.5e-12 45.3 1.3 6.9e-07 29.8 0.2 3.1 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB34341.1 - 6.8e-10 39.3 2.3 0.00076 20.0 0.1 4.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) SOCS_box PF07525.16 VBB34341.1 - 7.5e-10 39.0 3.3 2.1e-09 37.6 3.3 1.8 1 0 0 1 1 1 1 SOCS box Ank_5 PF13857.6 VBB34341.1 - 2.6e-05 24.4 3.8 0.00054 20.2 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB34341.1 - 0.0022 18.4 11.3 1.3 9.8 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 VBB34341.1 - 0.01 16.2 15.5 2.1 8.9 0.0 5.8 8 0 0 8 8 8 0 Ankyrin repeat VWA PF00092.28 VBB34344.1 - 1.8e-42 145.6 0.7 2.5e-42 145.1 0.7 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.15 VBB34344.1 - 1.3e-35 121.3 112.2 1.4e-07 31.6 4.7 10.5 10 0 0 10 10 10 7 Calcium-binding EGF domain EGF_3 PF12947.7 VBB34344.1 - 3e-30 104.1 116.5 3.5e-07 30.3 7.7 10.8 9 1 1 10 10 10 8 EGF domain hEGF PF12661.7 VBB34344.1 - 3.2e-21 75.2 93.9 5.3e-05 23.7 0.7 12.1 11 0 0 11 11 11 7 Human growth factor-like EGF EGF PF00008.27 VBB34344.1 - 4.4e-21 74.8 113.6 3.6e-05 24.0 3.2 11.3 10 1 0 10 10 10 7 EGF-like domain VWA_2 PF13519.6 VBB34344.1 - 1e-16 61.5 0.0 2.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_MSP1_1 PF12946.7 VBB34344.1 - 1.5e-09 37.8 94.0 0.00037 20.5 7.6 9.8 11 1 0 11 11 11 7 MSP1 EGF domain 1 FXa_inhibition PF14670.6 VBB34344.1 - 2.1e-09 37.5 108.7 0.011 16.0 3.0 10.8 9 1 1 10 10 10 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB34344.1 - 0.00014 21.7 72.1 0.014 15.3 0.3 10.6 11 0 0 11 11 11 6 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 VBB34344.1 - 0.0019 18.5 101.5 0.0033 17.7 7.5 9.1 9 0 0 9 9 9 5 Pvs28 EGF domain ClpB_D2-small PF10431.9 VBB34344.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein An_peroxidase PF03098.15 VBB34345.1 - 1.7e-100 337.1 0.0 1.9e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase TUDOR PF00567.24 VBB34346.1 - 8.5e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain zf-MYND PF01753.18 VBB34347.1 - 0.0002 21.4 22.0 0.0002 21.4 22.0 3.1 3 0 0 3 3 3 1 MYND finger TPR_12 PF13424.6 VBB34347.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.28 VBB34347.1 - 0.19 12.1 2.8 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 SET domain Moulting_cycle PF04870.16 VBB34349.1 - 3.7e-17 62.6 0.1 3.7e-17 62.6 0.1 2.3 2 1 0 2 2 2 1 Moulting cycle MH2 PF03166.14 VBB34350.1 - 9.2e-66 221.6 0.0 1.5e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 VBB34350.1 - 0.014 15.2 0.1 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Interferon-regulatory factor 3 DUF1325 PF07039.11 VBB34351.1 - 3e-21 75.9 0.1 1.7e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 SGF29 tudor-like domain MOZART1 PF12554.8 VBB34351.1 - 0.00032 20.4 0.4 0.00089 19.0 0.4 1.8 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Spaetzle PF16077.5 VBB34352.1 - 0.04 14.5 2.9 0.042 14.4 1.3 1.9 1 1 1 2 2 2 0 Spaetzle RGS PF00615.19 VBB34352.1 - 0.041 14.2 0.2 0.092 13.0 0.2 1.6 1 1 0 1 1 1 0 Regulator of G protein signaling domain SpoVT_C PF15714.5 VBB34353.1 - 0.49 10.5 3.5 1.7 8.7 0.3 3.0 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Pkinase PF00069.25 VBB34354.1 - 6.7e-44 150.2 0.2 1e-43 149.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34354.1 - 4.8e-24 85.0 0.1 7.3e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 VBB34354.1 - 0.003 17.2 1.1 0.0065 16.1 0.7 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 VBB34354.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cys_Met_Meta_PP PF01053.20 VBB34357.1 - 1.9e-07 30.0 0.0 2.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF5064 PF16703.5 VBB34357.1 - 0.042 14.3 0.1 0.068 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5064) zf-H2C2_5 PF13909.6 VBB34357.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF5305 PF17231.2 VBB34358.1 - 0.0087 15.5 2.3 0.01 15.2 2.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Mtc PF03820.17 VBB34358.1 - 0.043 12.9 5.3 0.048 12.7 5.3 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier Shisa PF13908.6 VBB34358.1 - 0.41 10.9 3.6 0.55 10.4 3.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PCSK9_C3 PF18463.1 VBB34358.1 - 0.49 10.6 8.1 0.65 10.3 8.1 1.3 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain RIFIN PF02009.16 VBB34358.1 - 7.5 6.3 9.1 9.8 6.0 9.1 1.1 1 0 0 1 1 1 0 Rifin NDK PF00334.19 VBB34360.1 - 8e-10 38.9 0.0 9.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Collagen PF01391.18 VBB34362.1 - 2.8e-24 84.6 93.8 4.7e-09 35.9 31.5 4.2 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) DUF5641 PF18701.1 VBB34364.1 - 1.6e-15 57.0 0.2 3e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 VBB34364.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF624 PF04854.14 VBB34364.1 - 0.038 14.1 0.5 0.07 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF624 BTB PF00651.31 VBB34365.1 - 9.2e-10 38.7 0.4 9e-09 35.6 0.0 2.1 1 1 0 2 2 2 1 BTB/POZ domain DUF1265 PF06887.14 VBB34365.1 - 0.0061 16.5 1.6 0.012 15.6 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1265) POTRA PF07244.15 VBB34365.1 - 0.035 14.7 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat Tugs PF17840.1 VBB34366.1 - 0.16 12.2 0.1 0.84 9.9 0.1 2.2 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain IFT20 PF14931.6 VBB34367.1 - 1.9e-29 102.3 7.3 2.1e-29 102.1 7.3 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Morc6_S5 PF17942.1 VBB34367.1 - 0.032 14.3 0.7 0.88 9.6 0.2 2.2 1 1 1 2 2 2 0 Morc6 ribosomal protein S5 domain 2-like CTV_P13 PF06922.11 VBB34367.1 - 0.15 12.2 0.7 0.53 10.4 0.2 1.8 1 1 1 2 2 2 0 Citrus tristeza virus P13 protein DUF3015 PF11220.8 VBB34367.1 - 0.22 11.4 0.4 0.26 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) EGF_CA PF07645.15 VBB34368.1 - 5.8e-09 36.0 17.3 8e-06 26.0 2.3 2.3 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 VBB34368.1 - 2.3e-05 24.5 17.0 3.3e-05 24.0 3.6 2.8 3 1 0 3 3 3 2 EGF domain cEGF PF12662.7 VBB34368.1 - 0.0026 17.6 8.0 0.12 12.3 1.2 3.0 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 VBB34368.1 - 0.012 15.9 3.9 0.012 15.9 3.9 3.1 3 2 0 3 3 3 0 EGF-like domain hEGF PF12661.7 VBB34368.1 - 0.013 16.1 13.1 0.14 12.8 2.5 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF FXa_inhibition PF14670.6 VBB34368.1 - 0.015 15.6 19.6 0.28 11.5 4.8 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 VBB34368.1 - 0.12 12.7 13.3 0.39 11.0 2.9 2.6 2 0 0 2 2 2 0 Pvs28 EGF domain SLC12 PF03522.15 VBB34369.1 - 2.9e-23 82.6 0.9 4e-17 62.4 1.0 2.0 1 1 1 2 2 2 2 Solute carrier family 12 SLC12 PF03522.15 VBB34370.1 - 1.7e-14 53.7 0.1 2.5e-14 53.1 0.0 1.4 1 1 1 2 2 2 1 Solute carrier family 12 Arf PF00025.21 VBB34371.1 - 1e-13 51.1 0.0 1.1e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-FPG_IleRS PF06827.14 VBB34371.1 - 0.074 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS His_Phos_2 PF00328.22 VBB34372.1 - 3.5e-27 95.8 5.5 1.6e-26 93.6 1.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 VBB34372.1 - 0.0062 16.2 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUP PF00674.18 VBB34372.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.4 2 1 0 2 2 2 0 DUP family CKS PF01111.19 VBB34373.1 - 5.5e-31 106.7 2.8 6.8e-31 106.4 2.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Acyl_transf_3 PF01757.22 VBB34375.1 - 3.7e-08 32.8 7.4 6.1e-08 32.1 4.7 2.1 2 0 0 2 2 2 1 Acyltransferase family Saf_2TM PF18303.1 VBB34375.1 - 0.012 15.2 2.4 0.2 11.2 0.1 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PIRT PF15099.6 VBB34375.1 - 0.053 13.1 0.4 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family GPR15L PF15854.5 VBB34375.1 - 0.11 12.7 0.9 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 RCR PF12273.8 VBB34375.1 - 0.36 11.5 1.4 0.77 10.4 0.1 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ferric_reduct PF01794.19 VBB34375.1 - 0.49 10.5 0.0 0.49 10.5 0.0 2.7 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF4957 PF16318.5 VBB34376.1 - 0.049 13.6 0.3 0.091 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) COP-gamma_platf PF08752.10 VBB34376.1 - 0.095 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain Ground-like PF04155.18 VBB34379.1 - 1e-15 58.1 2.5 2.9e-15 56.7 2.5 1.8 1 0 0 1 1 1 1 Ground-like domain EIIBC-GUT_N PF03612.14 VBB34379.1 - 0.3 10.8 4.0 0.61 9.8 4.0 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Papilin_u7 PF16626.5 VBB34380.1 - 0.032 14.8 0.1 0.039 14.5 0.1 1.2 1 0 0 1 1 1 0 Linking region between Kunitz_BPTI and I-set on papilin ATG16 PF08614.11 VBB34381.1 - 0.015 15.5 10.0 0.015 15.5 10.0 5.3 4 2 2 6 6 6 0 Autophagy protein 16 (ATG16) CSTF2_hinge PF14327.6 VBB34383.1 - 1.3e-29 102.4 3.4 1.3e-29 102.4 3.4 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 VBB34383.1 - 2.9e-22 78.2 0.0 5e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 VBB34383.1 - 2.3e-17 62.3 10.7 2.3e-17 62.3 10.7 3.2 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_8 PF11835.8 VBB34383.1 - 0.023 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain RRM_occluded PF16842.5 VBB34383.1 - 0.083 12.8 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Uteroglobin PF01099.17 VBB34383.1 - 0.56 10.6 2.7 1.2 9.5 0.3 2.5 1 1 1 2 2 2 0 Uteroglobin family MCM PF00493.23 VBB34384.1 - 6.4e-100 332.9 0.0 1.1e-99 332.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 VBB34384.1 - 9.2e-33 112.8 1.1 1.7e-32 112.0 1.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 VBB34384.1 - 2e-22 79.4 1.7 4.9e-22 78.2 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 VBB34384.1 - 8.1e-08 31.9 0.0 7.6e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 VBB34384.1 - 8.9e-07 29.0 0.1 5.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 VBB34384.1 - 2.1e-06 28.3 0.3 3.9e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.11 VBB34384.1 - 0.004 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 VBB34384.1 - 0.008 15.9 0.0 0.052 13.2 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_lid_2 PF17863.1 VBB34384.1 - 0.055 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA lid domain zf-C2H2_6 PF13912.6 VBB34385.1 - 0.021 14.8 2.2 0.41 10.7 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 VBB34385.1 - 0.15 13.0 12.9 1.4 10.0 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 VBB34385.1 - 2.5 8.7 12.0 6 7.5 0.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sugar_tr PF00083.24 VBB34386.1 - 4.1e-11 42.4 3.5 5.2e-11 42.1 3.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ANAPC4_WD40 PF12894.7 VBB34387.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_11 PF08241.12 VBB34389.1 - 8.3e-11 42.4 0.2 2.2e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 VBB34389.1 - 2.9e-07 31.1 0.1 8.8e-07 29.6 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 VBB34389.1 - 0.0048 17.6 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain YwiC PF14256.6 VBB34389.1 - 0.16 12.3 0.2 0.3 11.4 0.0 1.5 2 0 0 2 2 2 0 YwiC-like protein Cation_efflux PF01545.21 VBB34390.1 - 6.5e-20 71.7 5.7 1.1e-19 71.0 5.7 1.4 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 VBB34390.1 - 0.0011 18.2 5.0 0.25 10.5 0.1 2.6 2 1 0 2 2 2 2 ZIP Zinc transporter COQ7 PF03232.13 VBB34391.1 - 1.8e-24 86.4 0.0 2.2e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 VBB34391.1 - 0.044 14.2 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Rubrerythrin EF-hand_13 PF17958.1 VBB34394.1 - 1.2e-27 95.5 1.2 3.1e-26 91.0 0.0 3.4 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 VBB34394.1 - 8.7e-15 54.9 2.3 8.7e-14 51.7 0.1 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB34394.1 - 6.2e-09 35.1 0.6 0.00041 20.1 0.0 4.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 VBB34394.1 - 8.3e-09 34.4 3.0 4e-05 22.9 0.4 4.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 VBB34394.1 - 1e-07 31.1 2.3 5.8e-07 28.7 0.1 3.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 VBB34394.1 - 0.0036 17.1 2.3 0.022 14.6 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain pair PDEase_II PF02112.15 VBB34394.1 - 0.013 14.6 0.5 0.15 11.2 0.1 2.4 2 1 0 2 2 2 0 cAMP phosphodiesterases class-II FANCI_S1 PF14675.6 VBB34394.1 - 0.025 14.1 0.3 2.7 7.5 0.1 2.6 2 0 0 2 2 2 0 FANCI solenoid 1 SPARC_Ca_bdg PF10591.9 VBB34394.1 - 0.43 10.9 7.8 13 6.1 0.0 4.0 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Arteri_Gl PF00951.18 VBB34396.1 - 0.16 11.8 1.9 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DBP10CT PF08147.12 VBB34397.1 - 1e-11 44.9 1.5 1e-11 44.9 1.5 2.5 2 1 1 3 3 3 1 DBP10CT (NUC160) domain Cnn_1N PF07989.11 VBB34398.1 - 0.016 15.3 9.0 0.016 15.3 9.0 5.1 1 1 5 6 6 6 0 Centrosomin N-terminal motif 1 PAS_7 PF12860.7 VBB34398.1 - 0.023 14.9 0.3 0.023 14.9 0.3 2.8 1 1 2 4 4 4 0 PAS fold Abi_C PF14355.6 VBB34398.1 - 0.034 14.3 0.3 17 5.6 0.0 3.0 3 0 0 3 3 3 0 Abortive infection C-terminus UPF0242 PF06785.11 VBB34398.1 - 0.071 13.2 51.4 0.04 14.0 8.2 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DegT_DnrJ_EryC1 PF01041.17 VBB34398.1 - 0.13 11.5 5.8 0.062 12.6 3.6 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TPR_MLP1_2 PF07926.12 VBB34398.1 - 1.1 9.3 53.9 0.1 12.7 10.9 4.3 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 VBB34398.1 - 1.8 7.4 48.9 0.1 11.5 7.4 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF2813 PF11398.8 VBB34398.1 - 4.4 6.4 23.4 0.5 9.6 14.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2813) MctB PF11382.8 VBB34398.1 - 4.9 6.8 13.4 0.34 10.6 3.0 2.8 2 2 0 2 2 2 0 Copper transport outer membrane protein, MctB LBP_BPI_CETP PF01273.25 VBB34399.1 - 6.5e-09 35.6 0.1 8.1e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Gcd10p PF04189.13 VBB34400.1 - 4.1e-11 42.5 0.0 4.1e-11 42.5 0.0 2.1 1 1 1 2 2 2 1 Gcd10p family Rtf2 PF04641.12 VBB34400.1 - 0.0033 16.8 2.4 0.0044 16.4 2.4 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger AroM PF07302.11 VBB34400.1 - 0.011 15.1 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 AroM protein DUF2514 PF10721.9 VBB34400.1 - 0.87 9.6 5.7 1.3 9.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MOFRL PF05161.13 VBB34401.1 - 9.1e-32 109.5 0.0 1.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 MOFRL family DUF3867 PF12983.7 VBB34401.1 - 0.0048 17.0 0.0 0.0059 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3867) IMS_C PF11799.8 VBB34402.1 - 2.6e-10 41.0 0.0 6.2e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain YkyA PF10368.9 VBB34402.1 - 0.013 15.2 0.8 0.022 14.4 0.8 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Shikimate_dh_N PF08501.11 VBB34402.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain Patched PF02460.18 VBB34404.1 - 5.3e-26 91.0 0.0 6.3e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Patched family zf-H2C2_2 PF13465.6 VBB34406.1 - 4.4e-41 137.5 61.0 8.1e-09 35.5 1.5 8.5 9 0 0 9 9 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 VBB34406.1 - 2e-36 122.4 58.7 1.3e-05 25.3 0.5 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB34406.1 - 5.2e-26 89.1 57.4 0.0009 19.9 0.5 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB34406.1 - 2.8e-13 49.7 37.5 0.032 14.5 0.2 8.0 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB34406.1 - 1.2e-08 34.7 59.8 0.0027 17.6 1.4 7.9 8 0 0 8 8 7 5 C2H2-type zinc finger PyrI_C PF02748.15 VBB34406.1 - 0.00012 21.9 30.8 0.13 12.2 0.6 6.2 6 0 0 6 6 6 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 VBB34406.1 - 0.002 18.8 23.1 0.83 10.3 5.3 6.2 2 2 2 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 VBB34406.1 - 0.036 14.4 5.9 0.036 14.4 5.9 5.7 2 1 4 6 6 5 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 VBB34406.1 - 0.052 14.0 0.2 0.052 14.0 0.2 7.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Acetone_carb_G PF08882.11 VBB34406.1 - 0.089 12.9 3.2 2.2 8.5 0.2 2.9 2 2 0 2 2 2 0 Acetone carboxylase gamma subunit CobN-Mg_chel PF02514.16 VBB34406.1 - 0.13 10.0 0.0 0.16 9.7 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase zf-LYAR PF08790.11 VBB34406.1 - 0.21 11.5 0.3 0.21 11.5 0.3 6.2 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 VBB34406.1 - 0.22 11.2 27.5 0.33 10.6 0.4 7.1 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 VBB34406.1 - 0.43 11.3 28.8 2 9.2 2.1 4.5 2 1 2 4 4 3 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 VBB34406.1 - 0.68 9.9 37.4 10 6.1 0.3 6.6 5 2 1 6 6 6 0 SprT-like zinc ribbon domain FYVE PF01363.21 VBB34406.1 - 0.95 9.6 35.5 3.9 7.7 10.6 4.8 1 1 1 2 2 1 0 FYVE zinc finger C1_4 PF07975.12 VBB34406.1 - 1.1 9.6 33.9 1.2 9.5 1.0 5.3 2 2 4 6 6 6 0 TFIIH C1-like domain HalOD2 PF18547.1 VBB34406.1 - 1.6 8.7 5.1 3.4 7.6 0.3 3.2 3 0 0 3 3 3 0 Halobacterial output domain 2 zf-AN1 PF01428.16 VBB34406.1 - 1.7 8.9 39.9 0.55 10.4 2.1 7.8 8 0 0 8 8 8 0 AN1-like Zinc finger zinc_ribbon_9 PF14369.6 VBB34406.1 - 1.8 8.9 17.0 16 5.9 0.1 6.2 6 0 0 6 6 6 0 zinc-ribbon zf-MYST PF17772.1 VBB34406.1 - 1.9 8.1 0.0 1.9 8.1 0.0 5.4 4 2 2 7 7 7 0 MYST family zinc finger domain DUF3268 PF11672.8 VBB34406.1 - 2.4 8.5 26.9 0.3 11.4 1.5 4.4 1 1 4 6 6 6 0 zinc-finger-containing domain zf-C2HC_2 PF13913.6 VBB34406.1 - 4.5 7.3 32.3 11 6.0 0.1 7.1 7 0 0 7 7 6 0 zinc-finger of a C2HC-type APP_N PF02177.16 VBB34406.1 - 8.9 6.7 12.0 6.8 7.1 1.3 3.0 1 1 2 3 3 3 0 Amyloid A4 N-terminal heparin-binding Globin PF00042.22 VBB34407.1 - 1e-06 29.3 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Globin Sugar_tr PF00083.24 VBB34408.1 - 9.9e-09 34.5 8.3 3.6e-08 32.7 8.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Neur_chan_LBD PF02931.23 VBB34409.1 - 3.6e-06 26.6 0.8 2.1e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 VBB34409.1 - 5.9e-05 23.2 10.6 6.8e-05 23.0 7.9 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region RseC_MucC PF04246.12 VBB34409.1 - 0.58 10.1 3.0 0.25 11.3 0.6 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EamA PF00892.20 VBB34409.1 - 1.6 8.9 13.0 0.16 12.1 6.9 2.0 2 0 0 2 2 2 0 EamA-like transporter family DUF4131 PF13567.6 VBB34409.1 - 6 6.5 6.0 52 3.4 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) eIF_4G1 PF12152.8 VBB34410.1 - 0.052 13.7 0.1 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 Pkinase_Tyr PF07714.17 VBB34411.1 - 0.024 13.9 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Collagen PF01391.18 VBB34412.1 - 4.1e-11 42.5 30.9 1.7e-10 40.5 30.9 1.8 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M24 PF00557.24 VBB34413.1 - 9.5e-09 35.2 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Astacin PF01400.24 VBB34414.1 - 4.2e-69 232.0 0.1 5.9e-69 231.5 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 VBB34414.1 - 1.7e-39 134.6 0.1 4.2e-30 104.3 0.1 2.4 2 0 0 2 2 2 2 CUB domain Peptidase_M10 PF00413.24 VBB34414.1 - 0.025 14.5 0.3 0.091 12.6 0.3 1.9 1 1 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 VBB34414.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Desulfoferrod_N PF06397.12 VBB34414.1 - 0.037 13.6 0.4 0.54 9.9 0.1 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain GST_N_3 PF13417.6 VBB34415.1 - 3.2e-19 69.1 0.0 5.9e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 VBB34415.1 - 2.7e-12 46.8 0.4 8.3e-12 45.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 VBB34415.1 - 4.8e-11 42.8 0.1 2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 VBB34415.1 - 9.1e-06 25.6 0.1 1.5e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 VBB34415.1 - 7.7e-05 22.8 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 VBB34415.1 - 0.00046 20.4 0.0 0.00079 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 VBB34415.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 VBB34415.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain SARAF PF06682.12 VBB34416.1 - 7.4e-78 262.5 0.0 9.6e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Pkinase PF00069.25 VBB34417.1 - 1.2e-62 211.7 0.0 1.4e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34417.1 - 1.1e-29 103.5 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB34417.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB34417.1 - 0.00025 20.1 0.1 0.00034 19.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain POR PF01558.18 VBB34417.1 - 0.028 14.5 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Nucleotid_trans PF03407.16 VBB34418.1 - 8.7e-27 94.5 1.7 1.4e-26 93.8 1.7 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Collagen PF01391.18 VBB34420.1 - 1.3e-17 63.2 58.9 6.9e-10 38.5 26.2 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CAP_GLY PF01302.25 VBB34423.1 - 1e-20 73.5 0.7 1.5e-20 72.9 0.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain AMP-binding PF00501.28 VBB34424.1 - 7.9e-13 47.8 0.0 9.1e-13 47.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PAN_1 PF00024.26 VBB34425.1 - 1.3e-09 37.8 15.3 6e-06 26.1 7.9 2.7 2 0 0 2 2 2 2 PAN domain DUF3859 PF12975.7 VBB34425.1 - 0.061 13.3 0.4 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Ribosomal_60s PF00428.19 VBB34426.1 - 0.0073 16.9 6.8 0.0089 16.6 6.8 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein TALPID3 PF15324.6 VBB34426.1 - 0.22 9.2 7.1 0.26 8.9 7.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Ground-like PF04155.18 VBB34429.1 - 1.9e-13 50.8 0.0 1.9e-13 50.8 0.0 2.8 2 1 0 2 2 1 1 Ground-like domain TFIIA PF03153.13 VBB34429.1 - 5.8e-06 26.6 37.8 7.5e-06 26.2 37.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 VBB34429.1 - 0.0071 15.4 19.0 0.0092 15.0 19.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MRP-S31 PF15433.6 VBB34429.1 - 0.017 14.8 16.7 0.024 14.3 16.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.9 VBB34429.1 - 0.029 12.9 22.0 0.039 12.5 22.0 1.1 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 VBB34429.1 - 0.034 14.8 25.9 0.067 13.8 25.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 VBB34429.1 - 0.041 13.5 23.3 0.1 12.1 22.9 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 VBB34429.1 - 0.045 12.5 20.6 0.055 12.2 20.6 1.2 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 VBB34429.1 - 0.056 13.0 16.1 0.081 12.5 16.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCSAP PF15748.5 VBB34429.1 - 0.094 12.9 18.3 0.13 12.5 18.3 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hamartin PF04388.12 VBB34429.1 - 0.14 10.8 16.0 0.15 10.7 16.0 1.1 1 0 0 1 1 1 0 Hamartin protein TERB2 PF15101.6 VBB34429.1 - 0.14 12.2 24.2 0.28 11.2 24.2 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 VIR_N PF15912.5 VBB34429.1 - 0.17 11.5 17.3 0.26 10.9 17.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PAT1 PF09770.9 VBB34429.1 - 0.19 10.0 33.3 0.23 9.7 33.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TT_ORF1 PF02956.14 VBB34429.1 - 0.22 10.2 16.3 0.29 9.7 16.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 Otopetrin PF03189.13 VBB34429.1 - 0.26 10.1 7.2 0.29 9.9 7.2 1.1 1 0 0 1 1 1 0 Otopetrin Nop53 PF07767.11 VBB34429.1 - 0.38 10.1 24.2 0.54 9.6 24.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SpoIIP PF07454.11 VBB34429.1 - 0.38 10.2 20.5 0.61 9.5 19.3 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 VBB34429.1 - 0.39 10.1 13.6 0.54 9.6 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1788 PF08747.11 VBB34429.1 - 0.39 10.7 5.9 0.76 9.8 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) Ndc1_Nup PF09531.10 VBB34429.1 - 0.48 9.1 16.3 0.56 8.8 16.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 VBB34429.1 - 0.5 9.1 16.0 0.64 8.7 16.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 VBB34429.1 - 0.59 8.2 18.3 0.69 8.0 18.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 VBB34429.1 - 0.6 10.1 13.2 0.81 9.7 13.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 VBB34429.1 - 1 9.1 22.1 1.9 8.3 22.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Slu7 PF11708.8 VBB34429.1 - 1.2 8.8 23.6 2.5 7.8 23.6 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF853 PF05872.12 VBB34429.1 - 1.3 7.5 16.9 2 6.9 16.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Folliculin PF11704.8 VBB34429.1 - 1.3 8.9 11.8 2.2 8.2 11.8 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport MDM10 PF12519.8 VBB34429.1 - 1.3 7.8 15.1 1.6 7.5 15.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 VBB34429.1 - 1.3 7.7 15.5 1.9 7.2 15.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CSRNP_N PF16019.5 VBB34429.1 - 1.4 8.8 17.4 2.3 8.1 17.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tim54 PF11711.8 VBB34429.1 - 2.2 7.0 18.4 3.3 6.4 18.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0560 PF10577.9 VBB34429.1 - 2.3 6.6 31.7 3.3 6.1 31.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PepSY_TM PF03929.16 VBB34429.1 - 2.3 7.8 9.2 3.6 7.2 9.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM region PMSI1 PF15322.6 VBB34429.1 - 2.9 7.2 14.3 4.5 6.6 14.3 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF1764 PF08576.10 VBB34429.1 - 3 8.8 16.3 8.4 7.4 16.3 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GREB1 PF15782.5 VBB34429.1 - 3.8 4.5 21.9 4.4 4.3 21.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Radial_spoke_3 PF06098.11 VBB34429.1 - 4.1 6.6 29.5 5.4 6.2 28.9 1.4 2 0 0 2 2 1 0 Radial spoke protein 3 NARP1 PF12569.8 VBB34429.1 - 4.2 6.2 19.8 5.9 5.7 19.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EOS1 PF12326.8 VBB34429.1 - 4.2 7.3 10.2 8.2 6.3 10.2 1.5 1 0 0 1 1 1 0 N-glycosylation protein SWI-SNF_Ssr4 PF08549.10 VBB34429.1 - 4.4 5.8 26.8 5.8 5.4 26.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GET2 PF08690.10 VBB34429.1 - 4.9 6.7 22.8 6.8 6.3 22.8 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 MAJIN PF15077.6 VBB34429.1 - 5 6.8 15.5 7.6 6.3 15.5 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein FAM60A PF15396.6 VBB34429.1 - 5.1 7.1 17.1 9.3 6.2 17.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 VBB34429.1 - 5.4 5.2 20.1 7.3 4.8 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 VBB34429.1 - 5.6 5.9 15.1 7.6 5.5 15.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3408 PF11888.8 VBB34429.1 - 6.1 7.0 21.4 4.2 7.5 19.3 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3408) Baculo_PP31 PF05311.11 VBB34429.1 - 6.3 6.2 18.7 9.5 5.6 18.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SLC12 PF03522.15 VBB34429.1 - 7.2 5.5 24.3 10 5.0 24.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 VBB34429.1 - 7.8 5.3 15.4 11 4.8 15.4 1.3 1 0 0 1 1 1 0 Xrn1 helical domain PRC2_HTH_1 PF18118.1 VBB34429.1 - 9.7 7.1 15.8 2.6 8.9 12.0 2.0 2 1 0 2 2 1 0 Polycomb repressive complex 2 tri-helical domain Kelch_1 PF01344.25 VBB34430.1 - 1.5e-59 197.4 3.6 5e-14 51.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 VBB34430.1 - 1.9e-33 113.6 0.4 2e-08 34.2 0.0 6.2 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 VBB34430.1 - 3.7e-28 96.4 1.0 2e-08 33.9 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 VBB34430.1 - 1.1e-21 76.6 2.2 4.8e-05 23.3 0.0 5.9 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 VBB34430.1 - 7.9e-20 70.7 0.2 7.6e-05 22.9 0.0 6.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 VBB34430.1 - 4.6e-12 45.6 7.6 0.036 14.1 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Myb_DNA-bind_6 PF13921.6 VBB34430.1 - 0.094 13.0 0.0 40 4.6 0.1 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain Peptidase_C1 PF00112.23 VBB34431.1 - 1e-19 71.5 1.3 1e-19 71.5 1.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 VBB34431.1 - 0.059 12.1 0.2 0.064 12.0 0.2 1.0 1 0 0 1 1 1 0 Peptidase C1-like family Inhibitor_I29 PF08246.12 VBB34432.1 - 3.4e-06 27.4 1.0 3.4e-06 27.4 1.0 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Muted PF14942.6 VBB34432.1 - 0.0054 17.1 4.0 0.0071 16.7 3.5 1.4 1 1 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF349 PF03993.12 VBB34432.1 - 0.053 13.8 1.8 2.8 8.3 0.9 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Cytochrom_B562 PF07361.11 VBB34432.1 - 0.18 12.4 6.0 0.95 10.2 0.7 2.4 1 1 0 2 2 2 0 Cytochrome b562 Syntaxin_2 PF14523.6 VBB34432.1 - 0.4 11.1 2.6 1.9 8.9 0.1 2.4 1 1 1 2 2 2 0 Syntaxin-like protein SCVP PF17619.2 VBB34432.1 - 0.89 10.4 3.3 7.1 7.6 0.2 2.5 1 1 2 3 3 3 0 Secreted clade V proteins Prominin PF05478.11 VBB34433.1 - 5e-09 34.7 2.7 5e-09 34.7 2.7 2.2 1 1 0 1 1 1 1 Prominin Na_Ca_ex_C PF16494.5 VBB34433.1 - 0.0036 17.8 0.3 0.0076 16.7 0.3 1.5 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain CttA_N PF18244.1 VBB34433.1 - 4.5 7.8 6.4 1.4 9.4 0.2 2.8 3 0 0 3 3 3 0 Cellulose-binding protein CttA N-terminal domain HPD PF05044.12 VBB34435.1 - 8.7e-39 132.9 0.1 9.6e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Homeo-prospero domain DUF4422 PF14393.6 VBB34435.1 - 0.02 14.7 0.1 0.022 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Collagen PF01391.18 VBB34436.1 - 3.9e-13 49.0 30.3 1.3e-07 31.3 15.9 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Col_cuticle_N PF01484.17 VBB34436.1 - 8e-05 22.6 0.3 0.00011 22.2 0.3 1.2 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain PMT_4TMC PF16192.5 VBB34436.1 - 0.25 10.9 0.2 0.31 10.6 0.2 1.1 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase UCR_hinge PF02320.16 VBB34437.1 - 4.2e-18 65.3 2.7 5.3e-18 65.0 2.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DNA_pol3_delta2 PF13177.6 VBB34438.1 - 1.5e-12 47.6 0.0 3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 VBB34438.1 - 2.6e-07 30.8 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 VBB34438.1 - 6e-06 26.7 0.2 3.3e-05 24.3 0.0 2.2 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 VBB34438.1 - 5.2e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Rep_fac_C PF08542.11 VBB34438.1 - 9.4e-05 22.8 1.2 0.00048 20.5 0.0 2.6 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 VBB34438.1 - 0.00033 20.5 0.0 0.00084 19.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 VBB34438.1 - 0.0031 17.8 0.0 0.008 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 VBB34438.1 - 0.0088 16.3 0.1 0.098 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPgrasp_ST PF14397.6 VBB34438.1 - 0.0091 15.3 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp AAA_24 PF13479.6 VBB34438.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain S6PP PF05116.13 VBB34438.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Mg_chelatase PF01078.21 VBB34438.1 - 0.089 12.2 0.0 0.42 10.0 0.0 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 VBB34438.1 - 0.15 12.4 0.4 7.5 6.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain Prenyltransf PF01255.19 VBB34438.1 - 0.2 11.1 1.4 0.42 10.1 1.4 1.7 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase TspO_MBR PF03073.15 VBB34439.1 - 3.3e-18 66.0 7.2 4e-18 65.8 7.2 1.0 1 0 0 1 1 1 1 TspO/MBR family Ank_2 PF12796.7 VBB34442.1 - 1.2e-47 160.3 12.2 2.9e-14 53.4 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 VBB34442.1 - 3.1e-31 106.4 13.4 6e-07 29.6 0.2 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 VBB34442.1 - 2.5e-29 101.2 11.4 7.6e-07 29.6 0.1 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB34442.1 - 1.2e-27 95.6 12.0 9.7e-09 35.3 0.0 5.2 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB34442.1 - 3.3e-23 79.2 8.5 0.00078 19.7 0.0 8.4 8 1 0 8 8 8 6 Ankyrin repeat MIP PF00230.20 VBB34443.1 - 1.1e-15 58.0 5.1 1.3e-15 57.8 5.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein ThrE PF06738.12 VBB34443.1 - 0.53 9.6 3.5 0.59 9.5 2.9 1.4 1 1 0 1 1 1 0 Putative threonine/serine exporter MIP PF00230.20 VBB34444.1 - 4.6e-32 111.6 6.6 6e-32 111.2 6.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein EphA2_TM PF14575.6 VBB34445.1 - 0.15 12.9 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SR-25 PF10500.9 VBB34445.1 - 0.71 9.4 9.6 1.1 8.9 9.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chromadorea_ALT PF05535.12 VBB34446.1 - 1.4e-34 118.1 6.6 1.8e-34 117.8 6.6 1.1 1 0 0 1 1 1 1 Chromadorea ALT protein Fringe PF02434.16 VBB34447.1 - 0.061 12.8 0.0 0.091 12.2 0.0 1.3 1 1 0 1 1 1 0 Fringe-like Tubulin_C PF03953.17 VBB34448.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin C-terminal domain TPR_7 PF13176.6 VBB34449.1 - 0.00059 19.7 0.3 0.0017 18.2 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB34449.1 - 0.0023 17.9 2.1 0.005 16.9 1.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 VBB34449.1 - 0.0027 17.8 1.1 0.0064 16.6 1.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB34449.1 - 0.0047 16.7 0.5 0.014 15.2 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB34449.1 - 0.014 15.7 0.4 0.032 14.5 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 VBB34449.1 - 0.034 13.9 0.3 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 VBB34449.1 - 0.14 12.8 0.1 0.57 10.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Moulting_cycle PF04870.16 VBB34450.1 - 3.4e-15 56.2 5.2 3.4e-15 56.2 5.2 3.1 3 1 0 3 3 3 1 Moulting cycle NTR2 PF15458.6 VBB34450.1 - 0.001 18.7 0.1 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Cactin_mid PF10312.9 VBB34450.1 - 0.0018 18.0 3.4 0.0026 17.5 2.4 1.8 2 0 0 2 2 2 1 Conserved mid region of cactin DUF677 PF05055.12 VBB34450.1 - 9.4 5.0 14.4 6.7 5.5 9.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF2397 PF09660.10 VBB34451.1 - 0.15 11.0 0.0 0.19 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) EMI PF07546.13 VBB34452.1 - 0.04 14.7 2.7 0.04 14.7 2.7 2.4 2 1 0 2 2 2 0 EMI domain HSP20 PF00011.21 VBB34453.1 - 6.8e-23 80.8 0.2 9.3e-23 80.3 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 VBB34453.1 - 0.00025 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA COesterase PF00135.28 VBB34456.1 - 1.2e-114 384.0 0.0 1.5e-114 383.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 VBB34456.1 - 1.8e-09 37.8 0.9 2.3e-08 34.1 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.24 VBB34457.1 - 3.5e-57 194.4 0.0 2.3e-36 126.1 0.0 2.0 2 0 0 2 2 2 2 Zinc carboxypeptidase HNH_4 PF13395.6 VBB34457.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease Endostatin PF06482.11 VBB34458.1 - 4.1e-71 240.0 3.5 6.4e-71 239.4 3.1 1.5 1 1 0 1 1 1 1 Collagenase NC10 and Endostatin DUF1554 PF07588.11 VBB34458.1 - 0.00011 22.1 0.2 0.0013 18.6 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1554) Atg14 PF10186.9 VBB34460.1 - 0.033 13.3 2.0 0.037 13.1 2.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chorion_2 PF03964.15 VBB34460.1 - 1.9 9.4 7.3 3.1 8.7 7.2 1.4 1 1 0 1 1 1 0 Chorion family 2 CAP PF00188.26 VBB34461.1 - 1.3e-18 68.1 1.2 1.5e-18 67.8 1.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1041 PF06292.17 VBB34462.1 - 3.2e-19 69.3 4.6 2.5e-17 63.2 4.6 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1041) WD40 PF00400.32 VBB34463.1 - 2.6e-17 62.8 20.9 0.17 12.8 0.1 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB34463.1 - 4.7e-12 46.0 3.4 0.21 11.9 0.1 6.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB34463.1 - 3.3e-07 29.9 5.8 0.0051 16.2 1.2 2.3 1 1 1 2 2 2 2 WD40-like domain PALB2_WD40 PF16756.5 VBB34463.1 - 4.7e-05 22.5 1.8 0.0023 16.9 0.1 3.0 2 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Nitro_FeMo-Co PF02579.17 VBB34463.1 - 0.13 12.6 0.2 5.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor WD40 PF00400.32 VBB34464.1 - 2e-10 41.1 0.0 0.00054 20.7 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB34464.1 - 0.00087 19.5 0.4 0.15 12.4 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB34464.1 - 0.0021 17.5 0.3 0.0025 17.2 0.3 1.2 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 VBB34464.1 - 0.012 14.6 0.1 0.3 10.0 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M28 PF04389.17 VBB34465.1 - 4.6e-17 62.4 0.0 6.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 VBB34465.1 - 1.3e-15 57.2 0.0 3.3e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 VBB34465.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Nicastrin 7tm_1 PF00001.21 VBB34466.1 - 2.2e-15 56.7 18.8 2.2e-15 56.7 18.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TauE PF01925.19 VBB34466.1 - 2.6 7.6 19.2 1.6 8.3 16.5 1.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Actin PF00022.19 VBB34470.1 - 1.1e-96 324.0 0.0 4.4e-96 322.0 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 VBB34472.1 - 9.6e-06 25.1 0.0 1.2e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane PF01061.24 VBB34473.1 - 3.2e-19 69.2 14.0 1.6e-14 53.8 1.2 2.9 2 1 1 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 VBB34473.1 - 0.0024 18.4 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AhpC-TSA PF00578.21 VBB34474.1 - 1.7e-39 134.6 0.0 2.6e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB34474.1 - 8.3e-19 67.8 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 VBB34474.1 - 1.3e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 VBB34475.1 - 1.2e-39 135.0 0.0 1.7e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 VBB34475.1 - 5.5e-19 68.3 0.0 8.1e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Peptidase_C65 PF10275.9 VBB34476.1 - 1e-37 129.9 0.0 1.1e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain Med3 PF11593.8 VBB34478.1 - 0.014 14.6 3.6 0.014 14.6 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ASC PF00858.24 VBB34480.1 - 6.2e-63 213.3 3.2 8.1e-63 212.9 3.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SecA_SW PF07516.13 VBB34480.1 - 0.028 14.5 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 SecA Wing and Scaffold domain DAO_C PF16901.5 VBB34480.1 - 0.062 13.2 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase Ets PF00178.22 VBB34481.1 - 2.1e-35 121.0 0.4 2.1e-35 121.0 0.4 1.8 2 0 0 2 2 2 1 Ets-domain SUIM_assoc PF16619.5 VBB34481.1 - 0.004 17.2 2.9 0.0049 16.9 0.7 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Nucleo_P87 PF07267.11 VBB34481.1 - 0.031 13.2 5.0 0.04 12.8 5.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SprA-related PF12118.8 VBB34481.1 - 0.032 13.4 5.1 0.049 12.8 5.1 1.2 1 0 0 1 1 1 0 SprA-related family HSF_DNA-bind PF00447.17 VBB34481.1 - 0.033 14.8 2.2 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 HSF-type DNA-binding SelP_N PF04592.14 VBB34481.1 - 0.035 13.5 9.6 0.054 12.9 9.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 VBB34481.1 - 0.4 9.2 7.0 0.5 8.9 7.0 1.1 1 0 0 1 1 1 0 Macoilin family Androgen_recep PF02166.16 VBB34481.1 - 0.68 8.7 7.5 0.88 8.3 7.5 1.2 1 0 0 1 1 1 0 Androgen receptor RVT_1 PF00078.27 VBB34482.1 - 9.7e-10 38.3 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 VBB34482.1 - 4e-06 26.7 0.0 4.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Guanylate_cyc PF00211.20 VBB34483.1 - 1.5e-55 187.7 0.0 2.2e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 VBB34483.1 - 1.3e-15 57.5 1.8 2.6e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 VBB34483.1 - 0.0013 19.3 3.0 0.0023 18.5 3.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) SUIM_assoc PF16619.5 VBB34483.1 - 0.043 13.9 4.3 0.078 13.1 4.3 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 VBB34483.1 - 4.7 5.9 8.0 7.2 5.3 8.0 1.2 1 0 0 1 1 1 0 Androgen receptor Ephrin_rec_like PF07699.13 VBB34484.1 - 1e-38 130.8 49.2 1.9e-11 43.6 6.6 5.4 4 2 1 5 5 5 4 Putative ephrin-receptor like EGF_3 PF12947.7 VBB34484.1 - 2.7e-08 33.9 7.9 2.7e-08 33.9 7.9 2.6 2 0 0 2 2 2 1 EGF domain HYR PF02494.16 VBB34484.1 - 2.7e-05 24.4 0.0 0.00013 22.2 0.0 2.3 1 0 0 1 1 1 1 HYR domain EGF PF00008.27 VBB34484.1 - 0.00023 21.4 5.2 0.00023 21.4 5.2 3.8 3 0 0 3 3 3 1 EGF-like domain cEGF PF12662.7 VBB34484.1 - 0.00086 19.2 6.4 0.00086 19.2 6.4 5.5 7 0 0 7 7 7 1 Complement Clr-like EGF-like EGF_CA PF07645.15 VBB34484.1 - 0.00098 19.3 7.6 0.00098 19.3 7.6 6.5 5 2 1 6 6 6 1 Calcium-binding EGF domain hEGF PF12661.7 VBB34484.1 - 0.032 14.9 2.1 0.032 14.9 2.1 4.5 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 VBB34484.1 - 0.04 14.0 5.8 0.14 12.2 5.8 2.1 1 0 0 1 1 1 0 MSP1 EGF domain 1 LytR_C PF13399.6 VBB34484.1 - 0.075 14.0 0.1 0.14 13.1 0.1 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator DUF2318 PF10080.9 VBB34484.1 - 2.5 8.3 28.8 9.4 6.4 4.3 5.3 3 1 2 5 5 5 0 Predicted membrane protein (DUF2318) Radial_spoke_3 PF06098.11 VBB34485.1 - 0.0048 16.2 26.8 0.0048 16.2 26.8 3.0 1 1 1 3 3 3 1 Radial spoke protein 3 MRP-S31 PF15433.6 VBB34485.1 - 8.8 5.9 31.0 9.8 5.7 31.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 LRR_4 PF12799.7 VBB34486.1 - 1.3e-05 25.5 0.1 0.0034 17.8 0.0 3.4 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 VBB34486.1 - 0.0055 16.4 1.1 0.12 12.1 0.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 VBB34486.1 - 0.11 12.6 2.3 0.57 10.4 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Peptidase_M41 PF01434.18 VBB34488.1 - 1.4e-52 178.3 0.0 2.5e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 VBB34488.1 - 6.8e-45 152.7 0.0 1.5e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 VBB34488.1 - 2.5e-11 43.2 0.1 6.8e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 VBB34488.1 - 3.1e-10 40.4 0.0 8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 VBB34488.1 - 0.00045 20.2 0.0 0.0028 17.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 VBB34488.1 - 0.00053 19.8 0.0 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 VBB34488.1 - 0.00097 19.4 0.0 0.085 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 VBB34488.1 - 0.0023 18.0 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 VBB34488.1 - 0.0068 17.0 0.0 0.19 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 VBB34488.1 - 0.0069 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 VBB34488.1 - 0.0087 15.8 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 VBB34488.1 - 0.017 15.5 0.1 0.47 10.8 0.1 2.6 1 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 VBB34488.1 - 0.036 13.5 0.4 0.31 10.5 0.1 2.4 3 0 0 3 3 3 0 PhoH-like protein AAA_17 PF13207.6 VBB34488.1 - 0.056 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 VBB34488.1 - 0.075 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 VBB34488.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 VBB34488.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain I-set PF07679.16 VBB34492.1 - 6.8e-18 64.5 0.0 7.9e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB34492.1 - 5e-15 55.9 0.0 5.8e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 VBB34492.1 - 4.1e-11 42.9 0.0 5.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 VBB34492.1 - 3.6e-09 36.8 0.1 4.4e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB34492.1 - 0.00018 21.7 0.2 0.0041 17.3 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_5 PF16681.5 VBB34492.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.4 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Beta-Casp PF10996.8 VBB34493.1 - 2.5e-31 108.2 0.0 4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 VBB34493.1 - 7.5e-19 67.9 0.0 7e-18 64.8 0.0 2.1 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 VBB34493.1 - 2e-16 60.6 0.0 2.1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 VBB34493.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 VBB34493.1 - 5.4e-06 26.4 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 VBB34493.1 - 0.00018 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family WD40 PF00400.32 VBB34494.1 - 3.7e-05 24.4 5.3 0.019 15.8 0.9 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Motile_Sperm PF00635.26 VBB34495.1 - 1.5e-18 66.6 0.4 1.8e-18 66.3 0.4 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Eno-Rase_FAD_bd PF07055.12 VBB34496.1 - 0.025 15.0 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain PIF2 PF04631.12 VBB34498.1 - 0.059 12.2 0.1 0.068 12.0 0.1 1.2 1 0 0 1 1 1 0 Per os infectivity factor 2 NUDIX PF00293.28 VBB34499.1 - 1.6e-06 28.2 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ANF_receptor PF01094.28 VBB34500.1 - 9.6e-05 21.6 0.0 0.0003 20.0 0.0 1.7 1 1 1 2 2 2 1 Receptor family ligand binding region DUF383 PF04063.14 VBB34501.1 - 0.0016 18.1 0.1 0.0024 17.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF3870 PF12986.7 VBB34502.1 - 0.027 14.7 0.4 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) NUC173 PF08161.12 VBB34502.1 - 0.037 13.7 0.1 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 NUC173 domain JIP_LZII PF16471.5 VBB34502.1 - 0.037 14.2 0.4 0.15 12.3 0.4 2.0 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II GTP-bdg_N PF13167.6 VBB34502.1 - 0.042 14.5 1.9 0.68 10.6 0.0 3.5 4 0 0 4 4 4 0 GTP-binding GTPase N-terminal MOZ_SAS PF01853.18 VBB34503.1 - 2.6e-30 105.4 0.0 5.3e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 VBB34503.1 - 5.3e-18 64.4 0.2 1.7e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain TSP_1 PF00090.19 VBB34504.1 - 1.1e-30 105.6 84.5 7.8e-12 45.2 12.8 6.6 5 1 0 5 5 5 4 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 VBB34504.1 - 2.1e-10 41.0 1.0 2.1e-10 41.0 1.0 7.0 4 2 3 7 7 7 2 ADAM cysteine-rich domain Pentaxin PF00354.17 VBB34505.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Pentaxin family CC2-LZ PF16516.5 VBB34505.1 - 0.35 11.2 16.4 2.3 8.6 6.8 3.0 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator USP8_interact PF08941.10 VBB34505.1 - 0.38 10.5 5.2 5.7 6.7 0.1 2.5 2 1 0 2 2 2 0 USP8 interacting Filament PF00038.21 VBB34505.1 - 0.57 9.7 25.9 34 3.9 25.0 2.8 2 1 0 2 2 2 0 Intermediate filament protein DUF641 PF04859.12 VBB34505.1 - 1.4 9.2 18.6 1.7 9.0 2.8 3.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) LicD PF04991.13 VBB34505.1 - 2.2 8.4 5.8 12 6.0 4.8 2.0 2 0 0 2 2 2 0 LicD family Lebercilin PF15619.6 VBB34505.1 - 3.1 7.4 27.1 3.2 7.4 21.9 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 VBB34505.1 - 4 7.8 23.1 0.95 9.9 17.6 2.2 1 1 1 2 2 2 0 Fez1 Tetraspanin PF00335.20 VBB34508.1 - 2e-27 96.4 6.5 2.7e-27 96.0 6.5 1.2 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 VBB34508.1 - 0.04 13.7 5.7 0.04 13.7 5.1 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CD52 PF15116.6 VBB34508.1 - 0.061 13.4 0.1 0.061 13.4 0.1 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen Herpes_LMP1 PF05297.11 VBB34508.1 - 3.4 6.8 5.3 5.1 6.2 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4064 PF13273.6 VBB34508.1 - 3.9 7.8 14.3 8.6 6.7 12.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) LBP_BPI_CETP PF01273.25 VBB34509.1 - 4.5e-10 39.4 0.0 8.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain SUIM_assoc PF16619.5 VBB34509.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cytochrom_B558a PF05038.13 VBB34509.1 - 2.6 7.6 6.8 4.2 6.9 0.4 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Collagen PF01391.18 VBB34510.1 - 1.3e-11 44.1 28.8 8.9e-11 41.4 28.8 1.9 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) VWC PF00093.18 VBB34511.1 - 2.5e-24 85.4 161.1 7.1e-10 39.1 13.3 8.5 7 1 0 7 7 7 5 von Willebrand factor type C domain Antistasin PF02822.14 VBB34511.1 - 1.1e-12 48.4 43.8 2.8e-06 27.9 10.9 12.3 15 2 0 15 15 15 3 Antistasin family TILa PF12714.7 VBB34511.1 - 0.0003 20.7 32.2 0.00042 20.2 9.7 9.3 8 2 3 11 11 11 5 TILa domain Pacifastin_I PF05375.13 VBB34511.1 - 0.0072 16.0 3.9 0.0072 16.0 3.9 8.3 8 0 0 8 8 8 5 Pacifastin inhibitor (LCMII) PSP94 PF05825.11 VBB34511.1 - 0.012 16.2 10.3 0.012 16.2 10.3 6.8 4 3 2 6 6 6 0 Beta-microseminoprotein (PSP-94) TPR_14 PF13428.6 VBB34512.1 - 0.02 15.7 0.1 28 5.9 0.0 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 VBB34512.1 - 0.051 14.0 0.9 0.48 10.8 0.9 2.1 1 1 0 1 1 1 0 Bacterial transcriptional activator domain DUF4147 PF13660.6 VBB34513.1 - 6.2e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4147) Mur_ligase_M PF08245.12 VBB34514.1 - 0.0066 16.5 0.8 0.7 9.9 0.1 2.1 1 1 1 2 2 2 2 Mur ligase middle domain zf-C2H2_4 PF13894.6 VBB34515.1 - 0.039 14.8 0.0 0.096 13.6 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 VBB34515.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger AAA_5 PF07728.14 VBB34516.1 - 6.2e-24 84.6 0.0 1.8e-15 57.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 VBB34516.1 - 3.9e-12 46.9 0.0 5.9e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 VBB34516.1 - 8.5e-12 45.6 0.0 7.3e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 VBB34516.1 - 3.5e-09 36.8 1.1 5.2e-09 36.2 0.3 1.8 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_7 PF12775.7 VBB34516.1 - 4.3e-09 36.1 0.0 0.00044 19.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 VBB34516.1 - 1.1e-08 35.2 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 VBB34516.1 - 3.9e-07 30.3 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_6 PF12774.7 VBB34516.1 - 4.4e-07 29.2 0.4 0.00053 19.1 0.1 3.0 2 1 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 VBB34516.1 - 6.4e-07 29.3 0.0 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 VBB34516.1 - 2.3e-06 27.9 0.3 0.042 14.2 0.1 2.8 2 1 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 VBB34516.1 - 1e-05 25.3 0.0 0.08 12.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 VBB34516.1 - 1.3e-05 25.8 0.2 0.14 12.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 VBB34516.1 - 1.5e-05 24.8 0.1 0.051 13.3 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 VBB34516.1 - 2e-05 24.0 0.0 0.039 13.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 VBB34516.1 - 2.7e-05 24.1 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 VBB34516.1 - 3.2e-05 24.5 0.1 0.043 14.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 VBB34516.1 - 6.1e-05 23.0 0.3 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Rad17 PF03215.15 VBB34516.1 - 6.3e-05 23.0 0.1 0.037 13.9 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 VBB34516.1 - 9.8e-05 22.7 0.4 0.14 12.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 VBB34516.1 - 0.00012 22.7 0.0 0.45 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 VBB34516.1 - 0.00025 20.3 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PduV-EutP PF10662.9 VBB34516.1 - 0.00079 19.2 0.1 1.7 8.4 0.0 2.6 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 VBB34516.1 - 0.0024 17.3 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Roc PF08477.13 VBB34516.1 - 0.0028 17.9 0.1 0.51 10.6 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 VBB34516.1 - 0.005 16.6 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Prp19 PF08606.11 VBB34516.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ATPase_2 PF01637.18 VBB34516.1 - 0.0055 16.7 0.5 0.57 10.0 0.0 3.1 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 VBB34516.1 - 0.0089 16.2 0.1 5 7.2 0.1 3.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) SRPRB PF09439.10 VBB34516.1 - 0.011 15.2 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 VBB34516.1 - 0.013 15.6 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 VBB34516.1 - 0.017 14.9 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 VBB34516.1 - 0.018 14.9 0.6 8 6.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 VBB34516.1 - 0.022 15.1 0.1 12 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 VBB34516.1 - 0.025 14.1 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 VBB34516.1 - 0.026 14.3 0.0 0.071 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SSE PF00437.20 VBB34516.1 - 0.029 13.4 0.1 4.8 6.1 0.1 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.22 VBB34516.1 - 0.03 13.5 0.0 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 VBB34516.1 - 0.033 14.2 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 VBB34516.1 - 0.034 13.3 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain MCM PF00493.23 VBB34516.1 - 0.039 13.0 0.0 5.7 6.0 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain dNK PF01712.19 VBB34516.1 - 0.045 13.6 0.0 8.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase Mg_chelatase PF01078.21 VBB34516.1 - 0.055 12.8 0.0 8 5.8 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 VBB34516.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 VBB34516.1 - 0.063 12.9 0.1 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 VBB34516.1 - 0.085 12.9 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 VBB34516.1 - 0.092 12.8 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 VBB34516.1 - 0.1 12.3 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 VBB34516.1 - 0.1 11.8 0.0 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain ATP_bind_1 PF03029.17 VBB34516.1 - 0.13 12.0 0.1 7 6.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein LIM_bind PF01803.16 VBB34516.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Thyroglobulin_1 PF00086.18 VBB34517.1 - 2.2e-12 46.4 2.5 2.2e-12 46.4 2.5 1.8 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 VBB34517.1 - 1.5e-11 44.6 0.7 1.5e-11 44.6 0.7 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 VBB34517.1 - 0.00023 21.6 0.8 0.0043 17.5 0.4 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 VBB34517.1 - 0.0025 17.2 0.1 1.9 8.2 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 VBB34517.1 - 0.01 15.7 0.0 7.8 6.7 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain Glycogen_syn PF05693.13 VBB34519.1 - 1e-117 394.3 1.1 1.2e-85 288.4 0.0 2.0 1 1 1 2 2 2 2 Glycogen synthase Glyco_transf_5 PF08323.11 VBB34519.1 - 0.0019 17.9 0.2 0.0024 17.6 0.2 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 VBB34519.1 - 0.012 15.6 0.9 0.11 12.5 0.9 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Protoglobin PF11563.8 VBB34519.1 - 0.12 12.3 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Protoglobin Histone PF00125.24 VBB34521.1 - 1.7e-07 31.6 0.0 0.00049 20.5 0.0 2.1 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 Pacs-1 PF10254.9 VBB34521.1 - 0.052 12.5 0.1 4.8 6.0 0.0 2.1 1 1 1 2 2 2 0 PACS-1 cytosolic sorting protein Transposase_28 PF04195.12 VBB34521.1 - 0.16 12.2 0.0 0.94 9.7 0.0 2.1 3 0 0 3 3 3 0 Putative gypsy type transposon Histone PF00125.24 VBB34522.1 - 5.7e-24 85.0 9.9 9.7e-24 84.2 9.9 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB34522.1 - 7.8e-05 22.9 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Connexin PF00029.19 VBB34522.1 - 0.001 18.9 4.7 0.0013 18.6 4.7 1.3 1 0 0 1 1 1 1 Connexin DNA_pol_phi PF04931.13 VBB34522.1 - 0.0058 14.8 6.6 0.008 14.3 6.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi DDE_Tnp_1 PF01609.21 VBB34522.1 - 0.011 15.4 3.2 0.016 14.8 3.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain CDC45 PF02724.14 VBB34522.1 - 0.033 12.5 7.2 0.032 12.5 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 VBB34522.1 - 0.07 13.3 3.5 0.085 13.0 3.5 1.2 1 0 0 1 1 1 0 DDHD domain Folate_carrier PF01770.18 VBB34522.1 - 0.22 10.2 0.7 0.27 9.9 0.7 1.4 1 0 0 1 1 1 0 Reduced folate carrier Hid1 PF12722.7 VBB34522.1 - 0.28 9.3 7.8 0.32 9.1 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 VBB34522.1 - 0.3 9.8 7.8 0.34 9.6 7.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4637 PF15470.6 VBB34522.1 - 0.31 10.7 8.9 0.57 9.9 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RR_TM4-6 PF06459.12 VBB34522.1 - 0.39 10.5 13.3 0.53 10.1 13.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1764 PF08576.10 VBB34522.1 - 0.57 11.1 16.0 0.2 12.6 13.2 1.7 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) UNC-79 PF14776.6 VBB34522.1 - 0.58 8.9 4.3 0.68 8.6 4.3 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Neur_chan_memb PF02932.16 VBB34522.1 - 0.69 9.9 5.0 0.91 9.5 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 VBB34522.1 - 0.74 8.7 3.0 0.92 8.4 3.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.6 VBB34522.1 - 0.76 9.5 12.0 1.1 9.0 12.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2514 PF10721.9 VBB34522.1 - 0.81 9.7 6.1 3.5 7.6 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF3464 PF11947.8 VBB34522.1 - 0.87 9.3 5.6 1.5 8.6 5.6 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RNA_pol_Rpc4 PF05132.14 VBB34522.1 - 1.1 9.7 9.3 2.1 8.8 9.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 TCP PF03634.13 VBB34522.1 - 1.4 9.4 16.2 2.3 8.7 16.2 1.3 1 0 0 1 1 1 0 TCP family transcription factor DUF4337 PF14235.6 VBB34522.1 - 1.8 8.7 5.3 2.6 8.2 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_polI_A34 PF08208.11 VBB34522.1 - 2.1 8.4 20.4 2.8 8.0 20.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SID-1_RNA_chan PF13965.6 VBB34522.1 - 3.1 6.1 4.8 3.5 5.9 4.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4666 PF15697.5 VBB34522.1 - 6.2 7.6 10.8 2.3 9.0 7.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4666) DAG_kinase_N PF14513.6 VBB34522.1 - 7.7 6.7 13.2 85 3.3 0.0 2.3 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus Sec62 PF03839.16 VBB34522.1 - 8.3 5.9 11.1 13 5.2 11.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4484 PF14831.6 VBB34522.1 - 8.9 6.3 11.5 13 5.7 11.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) MOLO1 PF17175.4 VBB34523.1 - 1.7e-05 25.0 0.0 4.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 VBB34523.1 - 0.004 17.3 0.0 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 TPM domain Shisa PF13908.6 VBB34523.1 - 0.0052 17.1 0.1 0.0059 16.9 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF496 PF04363.12 VBB34523.1 - 0.047 13.7 0.2 0.2 11.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF496) EphA2_TM PF14575.6 VBB34523.1 - 0.086 13.7 0.1 0.13 13.1 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Thiamine_BP PF01910.17 VBB34524.1 - 0.064 13.2 0.9 0.18 11.7 0.8 2.0 1 1 1 2 2 2 0 Thiamine-binding protein ATG16 PF08614.11 VBB34526.1 - 0.066 13.4 24.4 0.044 14.0 20.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Ubiquitin_4 PF18036.1 VBB34526.1 - 0.25 11.4 3.3 0.29 11.2 0.5 2.5 1 1 0 2 2 2 0 Ubiquitin-like domain Tup_N PF08581.10 VBB34526.1 - 0.31 11.4 16.8 0.043 14.1 4.5 2.6 2 0 0 2 2 2 0 Tup N-terminal DUF724 PF05266.14 VBB34526.1 - 0.93 9.3 24.2 0.091 12.6 7.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) FUSC PF04632.12 VBB34526.1 - 1.4 7.4 5.4 2.1 6.8 5.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1729 PF08354.10 VBB34526.1 - 1.7 7.5 7.9 0.79 8.5 4.6 1.9 1 1 1 3 3 3 0 Domain of unknown function (DUF1729) Atg14 PF10186.9 VBB34526.1 - 4.7 6.2 21.0 0.39 9.7 11.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 VBB34526.1 - 9 5.5 22.2 1.2e+02 1.8 11.0 2.2 1 1 1 2 2 2 0 FAM76 protein SNARE PF05739.19 VBB34528.1 - 1.2e-05 25.2 0.2 1.8e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 SNARE domain Collagen PF01391.18 VBB34529.1 - 1.7e-17 62.9 72.0 1.4e-09 37.5 31.6 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) EcoRII-C PF09019.11 VBB34530.1 - 0.04 14.0 0.2 0.065 13.3 0.2 1.3 1 0 0 1 1 1 0 EcoRII C terminal WD40 PF00400.32 VBB34533.1 - 2.6e-24 85.0 9.4 3.3e-07 30.9 1.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 VBB34533.1 - 1.6e-05 25.1 0.2 0.038 14.3 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 VBB34533.1 - 0.025 13.9 0.0 0.12 11.7 0.0 1.8 1 1 1 2 2 2 0 WD40-like domain Collagen PF01391.18 VBB34535.1 - 0.00022 20.9 7.2 0.00036 20.2 7.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_A17 PF05380.13 VBB34535.1 - 0.00033 20.7 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 VBB34535.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Dicty_REP PF05086.12 VBB34536.1 - 0.13 10.2 7.8 0.14 10.2 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SH3_9 PF14604.6 VBB34537.1 - 2.4e-07 30.5 0.1 5.8e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 VBB34537.1 - 2.7e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain TPD52 PF04201.15 VBB34538.1 - 6.5e-36 123.4 6.0 9.6e-36 122.8 6.0 1.2 1 0 0 1 1 1 1 Tumour protein D52 family Band_3_cyto PF07565.13 VBB34538.1 - 0.0059 16.4 2.4 0.0068 16.2 2.4 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Fib_alpha PF08702.10 VBB34538.1 - 0.22 11.7 7.8 0.74 10.0 1.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ion_trans_2 PF07885.16 VBB34540.1 - 2.8e-21 75.3 14.4 2.8e-16 59.2 7.4 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 VBB34540.1 - 0.00016 21.0 3.3 0.00094 18.5 3.3 2.0 1 1 0 1 1 1 1 Ion transport protein DUF4536 PF15055.6 VBB34540.1 - 0.18 12.0 1.1 13 6.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF2975 PF11188.8 VBB34540.1 - 0.65 9.9 5.9 0.91 9.4 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Collagen PF01391.18 VBB34542.1 - 1.9e-11 43.6 26.2 3.5e-11 42.7 26.2 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Laminin_G_2 PF02210.24 VBB34543.1 - 7e-34 117.1 2.9 7.1e-20 71.9 0.2 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 VBB34543.1 - 1.1e-21 77.4 0.0 2.4e-12 47.2 0.0 3.1 3 0 0 3 3 3 2 Laminin G domain EGF PF00008.27 VBB34543.1 - 3e-05 24.2 3.0 3.3e-05 24.1 1.8 1.8 1 1 0 1 1 1 1 EGF-like domain hEGF PF12661.7 VBB34543.1 - 0.1 13.2 1.0 0.1 13.2 1.0 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 VBB34543.1 - 0.13 12.6 3.2 0.25 11.7 3.2 1.4 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 VBB34543.1 - 1.9 8.9 9.4 3.7 8.0 9.4 1.5 1 0 0 1 1 1 0 EGF-like domain RhoGEF PF00621.20 VBB34544.1 - 1.4e-34 119.9 2.3 2.6e-34 119.0 2.3 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_16 PF17838.1 VBB34544.1 - 6.1e-16 58.4 0.2 1.1e-15 57.6 0.2 1.4 1 0 0 1 1 1 1 PH domain C1_1 PF00130.22 VBB34544.1 - 7.6e-10 38.5 4.2 1.8e-09 37.3 4.2 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB34544.1 - 0.001 19.3 2.0 0.0028 17.9 2.0 1.7 1 0 0 1 1 1 1 C1 domain PHD PF00628.29 VBB34544.1 - 0.59 10.1 5.9 2.5 8.1 5.8 2.1 1 1 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 VBB34544.1 - 1.7 8.4 6.4 0.45 10.2 2.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 VBB34544.1 - 3.6 7.7 8.0 1 9.4 4.2 2.0 2 0 0 2 2 2 0 Double zinc ribbon PHD_2 PF13831.6 VBB34544.1 - 4.8 6.8 11.9 0.13 11.9 1.6 3.1 4 0 0 4 4 4 0 PHD-finger zf-RING_4 PF14570.6 VBB34545.1 - 0.0012 18.6 4.3 0.0022 17.7 4.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain YtfJ_HI0045 PF09695.10 VBB34545.1 - 0.013 15.1 0.6 0.077 12.6 0.4 1.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) zf-C3HC4 PF00097.25 VBB34545.1 - 0.014 15.2 4.5 0.032 14.1 4.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 VBB34545.1 - 0.03 14.2 4.6 0.06 13.2 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kelch_5 PF13854.6 VBB34546.1 - 2.9e-27 94.1 2.4 1.4e-06 28.1 0.0 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 VBB34546.1 - 1.6e-20 72.4 8.1 1.1e-05 24.9 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 VBB34546.1 - 8.2e-20 70.0 1.4 5.6e-06 26.1 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 VBB34546.1 - 2.7e-18 65.7 0.1 2.9e-06 27.2 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 VBB34546.1 - 5.6e-16 58.2 7.4 4e-07 30.1 0.5 5.3 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 VBB34546.1 - 2.8e-15 56.1 0.2 0.008 16.4 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain F5_F8_type_C PF00754.25 VBB34547.1 - 1.7e-15 57.2 0.0 1.1e-13 51.5 0.0 2.1 2 0 0 2 2 2 2 F5/8 type C domain IATP PF04568.12 VBB34548.1 - 3.8e-19 68.9 5.6 5.4e-19 68.4 5.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP rRNA_processing PF08524.11 VBB34548.1 - 0.045 13.8 8.6 0.058 13.4 8.6 1.1 1 0 0 1 1 1 0 rRNA processing Ntox15 PF15604.6 VBB34548.1 - 0.059 13.5 5.1 0.075 13.2 5.1 1.1 1 0 0 1 1 1 0 Novel toxin 15 DUF4407 PF14362.6 VBB34548.1 - 0.12 11.7 0.4 0.13 11.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_32 PF13654.6 VBB34548.1 - 0.18 10.6 4.7 0.2 10.4 4.7 1.0 1 0 0 1 1 1 0 AAA domain Radial_spoke_3 PF06098.11 VBB34548.1 - 5.4 6.2 13.9 7 5.8 13.9 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 Bax1-I PF01027.20 VBB34549.1 - 3.1e-21 76.2 36.8 3.7e-21 75.9 36.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF420 PF04238.12 VBB34549.1 - 0.64 10.3 22.8 3.5 7.9 7.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF420) Cadherin PF00028.17 VBB34550.1 - 5.6e-46 154.9 4.6 2.1e-11 44.1 0.0 5.1 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 VBB34550.1 - 0.00019 21.4 4.6 1.8 8.6 0.1 4.3 4 0 0 4 4 4 3 Cadherin-like RET_CLD1 PF17756.1 VBB34550.1 - 0.00037 20.8 0.0 0.037 14.3 0.0 2.7 2 0 0 2 2 2 1 RET Cadherin like domain 1 PalH PF08733.10 VBB34551.1 - 0.074 12.1 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 GLTT PF01744.20 VBB34551.1 - 0.27 11.0 1.3 0.36 10.6 0.8 1.5 2 0 0 2 2 2 0 GLTT repeat (6 copies) DUF5572 PF17733.1 VBB34552.1 - 5.3 7.0 17.4 6.7 6.6 1.3 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5572) MFS_1 PF07690.16 VBB34553.1 - 7.9e-31 107.2 14.6 9.2e-31 107.0 14.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB34553.1 - 1.4e-06 27.4 9.9 1.7e-06 27.2 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Phage_holin_2_3 PF16080.5 VBB34553.1 - 9.5 6.1 7.0 3.8 7.3 1.3 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Peptidase_C1 PF00112.23 VBB34554.1 - 6.7e-27 95.0 0.0 1.2e-26 94.2 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 VBB34554.1 - 0.0001 22.6 0.0 0.00029 21.2 0.0 1.8 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) 4F5 PF04419.14 VBB34554.1 - 0.00034 21.4 7.1 0.0007 20.4 7.1 1.5 1 0 0 1 1 1 1 4F5 protein family HHH_5 PF14520.6 VBB34556.1 - 0.0002 21.9 0.1 0.00044 20.8 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sigma70_r4 PF04545.16 VBB34556.1 - 0.038 13.5 0.0 14 5.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 Nop14 PF04147.12 VBB34557.1 - 0.19 9.9 18.6 0.2 9.9 18.6 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 VBB34557.1 - 0.33 10.3 12.2 0.37 10.1 12.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop25 PF09805.9 VBB34557.1 - 0.8 10.2 10.0 0.91 10.0 10.0 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CDC45 PF02724.14 VBB34557.1 - 1.2 7.3 15.4 1.4 7.2 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 VBB34557.1 - 2.6 6.0 29.0 2.9 5.9 29.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF727 PF05303.12 VBB34558.1 - 3.9e-35 120.1 0.0 4.5e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) BTB PF00651.31 VBB34559.1 - 2.4e-18 66.4 0.2 3.5e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 VBB34559.1 - 1.5e-11 44.3 0.4 3.1e-09 36.9 0.4 2.6 1 1 1 2 2 2 2 BTB And C-terminal Kelch PDEase_I PF00233.19 VBB34560.1 - 6.9e-66 222.4 6.8 9.2e-66 222.0 6.8 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 VBB34560.1 - 0.071 13.3 0.2 0.15 12.3 0.2 1.8 1 1 0 1 1 1 0 HD domain Opiods_neuropep PF01160.18 VBB34560.1 - 0.11 12.6 0.6 0.24 11.5 0.6 1.6 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Folate_carrier PF01770.18 VBB34563.1 - 1.6e-73 247.8 27.0 3.9e-73 246.6 27.0 1.5 1 1 0 1 1 1 1 Reduced folate carrier DUF3630 PF12305.8 VBB34563.1 - 0.18 11.9 1.2 11 6.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3630) Pkinase PF00069.25 VBB34564.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain EGF PF00008.27 VBB34565.1 - 0.00064 20.0 61.1 0.0081 16.4 8.8 5.6 6 0 0 6 6 6 3 EGF-like domain EGF_2 PF07974.13 VBB34565.1 - 0.0013 19.1 57.9 0.031 14.6 12.2 4.6 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 VBB34565.1 - 0.024 15.3 6.0 0.024 15.3 6.0 5.9 6 0 0 6 6 6 0 Human growth factor-like EGF Cpn10 PF00166.21 VBB34567.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit DUF1616 PF07760.11 VBB34569.1 - 0.041 13.3 0.6 0.055 12.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Bax1-I PF01027.20 VBB34570.1 - 1.7e-22 80.3 37.5 1.9e-22 80.1 37.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF420 PF04238.12 VBB34570.1 - 0.69 10.2 23.1 3.8 7.8 7.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF420) TT_ORF2 PF02957.15 VBB34571.1 - 0.0081 17.1 3.3 0.01 16.7 3.3 1.2 1 0 0 1 1 1 1 TT viral ORF2 PCI PF01399.27 VBB34572.1 - 1.4e-17 64.1 1.3 1.2e-16 61.1 0.2 2.5 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 VBB34572.1 - 0.00022 21.0 0.8 0.00051 19.8 0.8 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 VBB34572.1 - 0.0019 18.7 3.2 0.036 14.6 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB34572.1 - 0.028 14.7 2.8 0.54 10.6 0.6 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB34572.1 - 0.029 14.6 1.5 7.4 7.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN4_RPN5_eIF3a PF18420.1 VBB34572.1 - 0.033 14.3 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain TPR_14 PF13428.6 VBB34572.1 - 0.92 10.5 4.0 35 5.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat An_peroxidase PF03098.15 VBB34573.1 - 4.2e-42 144.4 0.3 1.5e-37 129.4 0.3 3.1 1 1 0 1 1 1 1 Animal haem peroxidase INCENP_ARK-bind PF03941.15 VBB34574.1 - 5.2e-07 29.5 2.2 0.011 15.6 0.1 2.7 2 0 0 2 2 2 2 Inner centromere protein, ARK binding region MFS_1 PF07690.16 VBB34575.1 - 0.00031 19.8 5.7 0.0004 19.4 5.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF21 PF01595.20 VBB34575.1 - 0.011 15.5 1.6 0.018 14.8 1.6 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain TraW_N PF12477.8 VBB34575.1 - 0.1 12.5 0.8 0.32 11.0 0.3 2.0 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal DUF2417 PF10329.9 VBB34575.1 - 0.11 11.9 2.7 0.14 11.6 2.7 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) YfhO PF09586.10 VBB34575.1 - 0.46 8.7 5.9 0.48 8.6 5.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2207 PF09972.9 VBB34575.1 - 1.3 7.7 4.5 1.5 7.5 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC_membrane PF00664.23 VBB34576.1 - 2.8e-42 145.3 17.3 3.6e-42 144.9 17.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 VBB34576.1 - 5.4e-09 36.7 0.1 1.5e-08 35.3 0.1 1.8 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 VBB34576.1 - 0.00081 19.3 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 VBB34576.1 - 0.0074 16.7 0.1 0.24 11.8 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain PRK PF00485.18 VBB34576.1 - 0.013 15.2 1.1 0.077 12.7 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 VBB34576.1 - 0.026 13.7 1.1 0.085 12.0 0.0 2.2 3 0 0 3 3 3 0 G-protein alpha subunit AAA_15 PF13175.6 VBB34576.1 - 0.044 13.5 1.4 0.1 12.3 0.1 2.1 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 VBB34576.1 - 0.046 13.0 0.2 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 VBB34576.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 VBB34576.1 - 0.07 12.9 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 VBB34576.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain COX6C PF02937.15 VBB34576.1 - 0.31 11.2 3.0 1.2 9.3 0.1 3.3 2 1 2 4 4 4 0 Cytochrome c oxidase subunit VIc Cation_efflux PF01545.21 VBB34576.1 - 0.89 9.2 10.2 0.12 12.1 6.0 1.7 2 0 0 2 2 2 0 Cation efflux family Peptidase_M10 PF00413.24 VBB34580.1 - 2.9e-20 72.7 0.1 4.9e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 VBB34580.1 - 0.0024 17.5 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 VBB34580.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_3 PF13582.6 VBB34580.1 - 0.015 15.8 0.0 0.056 14.0 0.0 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like TMEM154 PF15102.6 VBB34580.1 - 0.034 14.0 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Metallopep PF12044.8 VBB34580.1 - 0.034 12.7 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 VBB34580.1 - 0.054 12.4 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 VBB34580.1 - 0.099 12.8 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 VBB34580.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Met-zincin MFS_1 PF07690.16 VBB34581.1 - 1.2e-21 77.0 16.2 3.6e-19 68.9 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB34581.1 - 2.8e-07 29.8 9.6 3.5e-07 29.5 9.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PH PF00169.29 VBB34582.1 - 4.1e-14 53.0 0.2 9e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 VBB34582.1 - 0.0013 18.9 1.1 0.0027 17.9 1.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 VBB34582.1 - 0.012 16.0 2.0 0.012 16.0 2.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain DUF5349 PF17298.2 VBB34582.1 - 0.019 14.8 3.4 0.026 14.3 3.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) PH_4 PF15404.6 VBB34582.1 - 0.021 14.6 0.1 0.021 14.6 0.1 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain MS_channel PF00924.18 VBB34582.1 - 0.12 11.9 1.1 0.15 11.6 1.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel Dicty_REP PF05086.12 VBB34582.1 - 0.22 9.5 8.2 0.24 9.4 8.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 VBB34582.1 - 0.28 9.3 13.9 0.62 8.1 12.6 1.8 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Mucin PF01456.17 VBB34582.1 - 0.42 10.6 26.8 0.67 9.9 26.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 VBB34582.1 - 1.8 8.5 17.4 3.4 7.6 17.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF5401 PF17380.2 VBB34582.1 - 2.4 6.1 6.1 3.3 5.7 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Macoilin PF09726.9 VBB34583.1 - 1.6 7.2 12.1 1.8 7.0 12.1 1.0 1 0 0 1 1 1 0 Macoilin family PDGF_N PF04692.13 VBB34583.1 - 3.1 8.6 5.2 0.69 10.7 1.6 1.8 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region LIM PF00412.22 VBB34584.1 - 0.0022 18.2 0.6 0.0026 17.9 0.6 1.1 1 0 0 1 1 1 1 LIM domain Cytochrome_CBB3 PF13442.6 VBB34584.1 - 0.068 13.5 0.1 0.074 13.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III FRG1 PF06229.12 VBB34585.1 - 0.084 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 FRG1-like domain GMP_PDE_delta PF05351.11 VBB34586.1 - 7.3e-54 182.1 0.6 1.1e-53 181.4 0.6 1.3 1 0 0 1 1 1 1 GMP-PDE, delta subunit E1-E2_ATPase PF00122.20 VBB34587.1 - 1.2e-55 187.8 2.2 1.6e-53 180.9 0.1 2.3 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 VBB34587.1 - 4.8e-18 64.6 2.0 1.7e-17 62.8 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 VBB34587.1 - 2.9e-17 62.5 0.0 5.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 VBB34587.1 - 0.085 13.1 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SirB PF04247.12 VBB34587.1 - 0.16 12.1 1.7 0.27 11.3 0.3 1.9 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Drf_GBD PF06371.13 VBB34588.1 - 0.017 14.7 0.1 0.018 14.6 0.1 1.0 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain SMP_C2CD2L PF18696.1 VBB34589.1 - 1e-06 28.7 0.0 0.0068 16.3 0.0 2.4 2 0 0 2 2 2 2 Synaptotagmin-like, mitochondrial and lipid-binding domain Secretin_N_2 PF07655.13 VBB34589.1 - 9.6e-05 22.9 3.8 0.28 11.7 0.3 2.5 2 0 0 2 2 2 2 Secretin N-terminal domain Herpes_IR6 PF06307.12 VBB34589.1 - 0.00042 19.9 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 2 Herpesvirus IR6 protein Ldl_recept_a PF00057.18 VBB34591.1 - 1.3e-15 57.3 23.4 2e-09 37.5 7.6 3.5 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A DUF3402 PF11882.8 VBB34592.1 - 0.029 13.5 0.1 0.035 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) RED_C PF07807.11 VBB34594.1 - 4.2 7.9 6.7 2.4 8.6 0.5 3.3 2 1 2 4 4 4 0 RED-like protein C-terminal region Cadherin PF00028.17 VBB34596.1 - 8.2e-61 202.5 1.2 2.5e-14 53.5 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 VBB34596.1 - 0.17 11.8 0.0 64 3.5 0.0 3.9 4 0 0 4 4 4 0 Cadherin-like DSPc PF00782.20 VBB34597.1 - 5.8e-34 116.8 0.2 1.5e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 VBB34597.1 - 2.2e-11 43.5 3.0 4.7e-11 42.4 3.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 VBB34597.1 - 0.0022 17.6 0.6 0.0079 15.8 0.6 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Vel1p PF10339.9 VBB34597.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive PTPlike_phytase PF14566.6 VBB34597.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 VBB34597.1 - 0.13 12.6 0.1 2.1 8.7 0.0 2.6 2 1 0 2 2 2 0 Rit1 DUSP-like domain NeA_P2 PF12312.8 VBB34598.1 - 5 6.5 5.9 9.5 5.6 0.1 3.0 3 0 0 3 3 3 0 Nepovirus subgroup A polyprotein HTH_psq PF05225.16 VBB34599.1 - 1.9e-14 53.1 0.4 3.9e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain MT-A70 PF05063.14 VBB34602.1 - 4.3e-27 95.1 0.1 3.4e-26 92.2 0.1 1.9 1 1 0 1 1 1 1 MT-A70 tRNA-synt_1c PF00749.21 VBB34604.1 - 2.2e-70 237.1 0.0 2.9e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PSS PF03034.15 VBB34604.1 - 2.1e-24 86.7 4.2 2.2e-24 86.7 2.3 1.9 2 0 0 2 2 2 1 Phosphatidyl serine synthase Ig_3 PF13927.6 VBB34608.1 - 6.4e-15 55.5 3.0 3.7e-05 24.2 0.1 3.7 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 VBB34608.1 - 1.2e-10 41.3 0.3 0.0018 18.3 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 VBB34608.1 - 6.1e-10 39.1 2.3 0.0013 18.8 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 VBB34608.1 - 1.5e-06 28.5 3.2 0.0098 16.2 0.2 3.4 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 VBB34608.1 - 8.6e-05 22.7 0.6 0.079 13.1 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin V-set domain fn3 PF00041.21 VBB34608.1 - 9.6e-05 22.7 0.0 0.00062 20.1 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III domain Izumo-Ig PF16706.5 VBB34608.1 - 0.0021 18.1 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 VBB34608.1 - 0.0046 16.5 0.0 0.13 11.9 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set_CD47 PF08204.11 VBB34608.1 - 0.11 12.5 2.2 4.2 7.4 0.1 2.7 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Ephrin PF00812.17 VBB34610.1 - 5.4e-22 78.3 0.0 6.5e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Ephrin A_deaminase PF00962.22 VBB34612.1 - 1e-68 232.1 0.0 1.2e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 VBB34612.1 - 0.07 12.4 0.3 0.2 10.9 0.2 1.9 2 1 0 2 2 2 0 Amidohydrolase family eIF-3_zeta PF05091.12 VBB34613.1 - 2.6e-05 23.4 7.9 2.6e-05 23.4 7.9 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AF-4 PF05110.13 VBB34613.1 - 0.016 13.3 14.8 0.015 13.4 14.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3464 PF11947.8 VBB34613.1 - 0.082 12.7 12.9 0.12 12.1 12.9 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 WDCP PF15390.6 VBB34613.1 - 0.13 10.6 7.8 0.15 10.4 7.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family EPL1 PF10513.9 VBB34613.1 - 0.14 12.6 12.0 0.16 12.4 12.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 VBB34613.1 - 0.17 11.8 34.6 0.19 11.7 34.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 VBB34613.1 - 0.22 10.9 21.8 0.33 10.3 21.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 VBB34613.1 - 0.3 10.3 9.3 0.33 10.1 9.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PepSY_TM PF03929.16 VBB34613.1 - 0.52 9.9 5.1 0.58 9.8 5.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region TMEM51 PF15345.6 VBB34613.1 - 0.53 10.1 10.5 0.67 9.7 10.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FAM76 PF16046.5 VBB34613.1 - 0.57 9.5 16.2 0.69 9.2 16.2 1.0 1 0 0 1 1 1 0 FAM76 protein FAM176 PF14851.6 VBB34613.1 - 0.59 9.8 9.3 0.8 9.4 9.3 1.1 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 VBB34613.1 - 0.79 8.4 16.0 0.81 8.4 16.0 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 VBB34613.1 - 0.82 8.1 19.1 0.92 7.9 19.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Orbi_VP2 PF00898.17 VBB34613.1 - 0.97 7.1 8.6 1.1 6.9 8.6 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Membralin PF09746.9 VBB34613.1 - 1.1 8.2 8.0 1.2 8.1 8.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Macoilin PF09726.9 VBB34613.1 - 1.4 7.4 14.2 1.5 7.3 14.2 1.0 1 0 0 1 1 1 0 Macoilin family Tim54 PF11711.8 VBB34613.1 - 1.4 7.6 12.6 1.5 7.5 12.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SRP72 PF08492.12 VBB34613.1 - 1.5 9.3 3.9 3.5 8.1 3.9 1.7 1 1 0 1 1 1 0 SRP72 RNA-binding domain Comm PF15957.5 VBB34613.1 - 1.5 9.2 5.8 2.1 8.7 5.8 1.2 1 0 0 1 1 1 0 Commissureless CDC45 PF02724.14 VBB34613.1 - 1.5 7.0 11.5 1.8 6.8 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.9 VBB34613.1 - 2.3 6.4 28.7 2.4 6.3 28.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 VBB34613.1 - 2.3 7.5 14.2 3.1 7.1 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 VBB34613.1 - 2.5 6.7 9.8 2.5 6.7 9.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 VBB34613.1 - 2.8 8.2 18.4 3.6 7.8 18.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Velvet PF11754.8 VBB34613.1 - 2.9 7.8 15.3 3.2 7.6 15.3 1.1 1 0 0 1 1 1 0 Velvet factor Cellulose_synt PF03552.14 VBB34613.1 - 3.4 6.0 4.5 4 5.8 4.5 1.0 1 0 0 1 1 1 0 Cellulose synthase Suf PF05843.14 VBB34613.1 - 3.5 7.5 17.8 4.4 7.2 17.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 VBB34613.1 - 3.6 7.5 12.7 4.4 7.2 12.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Connexin PF00029.19 VBB34613.1 - 4 7.1 11.3 4.9 6.8 11.3 1.1 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 VBB34613.1 - 4 7.6 12.5 5.3 7.2 12.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ORC_WH_C PF18137.1 VBB34613.1 - 5.1 7.2 13.8 7.6 6.6 13.8 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal EIIBC-GUT_N PF03612.14 VBB34613.1 - 5.3 6.7 11.2 6.7 6.4 11.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Otopetrin PF03189.13 VBB34613.1 - 5.5 5.7 8.7 6.2 5.5 8.7 1.1 1 0 0 1 1 1 0 Otopetrin NST1 PF13945.6 VBB34613.1 - 5.8 7.0 21.5 7.7 6.6 21.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Lin-8 PF03353.15 VBB34613.1 - 6.1 6.3 20.8 6.5 6.2 20.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ureide_permease PF07168.11 VBB34613.1 - 6.4 5.4 7.5 9.4 4.9 7.5 1.2 1 0 0 1 1 1 0 Ureide permease SLC12 PF03522.15 VBB34613.1 - 7.4 5.5 16.0 8.7 5.2 16.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Dynactin_p62 PF05502.13 VBB34613.1 - 7.4 5.2 13.0 8.9 5.0 13.0 1.0 1 0 0 1 1 1 0 Dynactin p62 family DUF4770 PF15994.5 VBB34613.1 - 7.6 6.7 17.0 9.8 6.4 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Gti1_Pac2 PF09729.9 VBB34613.1 - 7.9 6.5 14.0 9.8 6.2 14.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family OATP PF03137.20 VBB34613.1 - 9.5 4.4 10.1 11 4.2 10.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RhoGEF PF00621.20 VBB34614.1 - 6.1e-09 36.4 0.0 9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 VBB34614.1 - 0.041 14.4 0.1 0.079 13.5 0.1 1.4 1 0 0 1 1 1 0 PH domain AMMECR1 PF01871.17 VBB34615.1 - 5.7e-08 32.5 0.0 7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 RRM_1 PF00076.22 VBB34616.1 - 2.6e-17 62.4 0.0 5.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 VBB34616.1 - 0.00058 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 VBB34616.1 - 0.017 15.1 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 VBB34616.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.1 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-B_box PF00643.24 VBB34617.1 - 9.9e-10 38.4 34.3 3.6e-06 27.0 12.2 3.9 4 1 0 4 4 4 2 B-box zinc finger CEBP_ZZ PF16366.5 VBB34617.1 - 1e-05 25.6 3.4 1e-05 25.6 3.4 2.9 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 VBB34617.1 - 4.3 7.6 23.7 0.22 11.8 3.8 3.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Flg_bb_rod PF00460.20 VBB34618.1 - 1.1 9.2 4.5 5.1 7.1 3.9 2.1 2 0 0 2 2 2 0 Flagella basal body rod protein Band_7 PF01145.25 VBB34620.1 - 6.8e-05 22.9 0.0 7.7e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family pPIWI_RE_REase PF18154.1 VBB34620.1 - 0.084 12.8 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 REase associating with pPIWI_RE IRK_C PF17655.1 VBB34621.1 - 1.2e-22 80.4 0.0 1.3e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Bac_transf PF02397.16 VBB34621.1 - 0.039 13.6 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial sugar transferase HicB-like_2 PF15970.5 VBB34621.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system 7tm_1 PF00001.21 VBB34622.1 - 2e-12 47.0 15.1 2.6e-12 46.6 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 VBB34622.1 - 1.2e-09 37.9 13.8 3.5e-08 33.1 13.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Glyco_hydro_31 PF01055.26 VBB34623.1 - 7.1e-74 249.6 0.1 7.9e-74 249.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NUDIX_2 PF13869.6 VBB34623.1 - 2.4e-40 138.1 0.1 3.5e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase Claudin_3 PF06653.11 VBB34624.1 - 2.9e-11 43.6 5.4 5e-11 42.8 5.4 1.4 1 1 0 1 1 1 1 Tight junction protein, Claudin-like SPT_ssu-like PF11779.8 VBB34624.1 - 0.016 14.8 0.4 0.016 14.8 0.4 3.9 4 0 0 4 4 4 0 Small subunit of serine palmitoyltransferase-like Clc-like PF07062.12 VBB34624.1 - 0.71 9.3 16.9 4.2 6.8 12.4 3.0 1 1 1 2 2 2 0 Clc-like DUF2207 PF09972.9 VBB34624.1 - 2.4 6.8 6.5 2.5 6.7 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) VWD PF00094.25 VBB34625.1 - 1.8e-11 44.6 0.0 3.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 VBB34625.1 - 0.00073 19.9 3.5 0.002 18.5 3.5 1.8 1 0 0 1 1 1 1 C8 domain Collagen PF01391.18 VBB34627.1 - 2.6e-16 59.1 73.3 7.2e-07 28.9 45.7 3.1 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) DuoxA PF10204.9 VBB34628.1 - 2.2e-55 187.6 3.2 2.5e-55 187.4 3.2 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Transp_cyt_pur PF02133.15 VBB34628.1 - 0.0043 15.9 2.8 0.0056 15.5 2.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 VBB34629.1 - 6.5e-42 143.7 0.0 1e-41 143.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34629.1 - 2e-40 138.7 0.0 1.1e-39 136.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase zf-C2H2_jaz PF12171.8 VBB34629.1 - 0.01 16.1 0.4 0.01 16.1 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 VBB34629.1 - 0.016 15.6 0.8 0.11 13.0 0.8 2.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB34629.1 - 0.021 15.6 2.3 0.12 13.2 0.7 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 VBB34629.1 - 0.08 13.4 0.7 0.08 13.4 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type G-alpha PF00503.20 VBB34630.1 - 1.8e-103 346.4 2.7 2.2e-103 346.2 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 VBB34630.1 - 8.6e-16 57.9 1.8 1.1e-12 47.8 0.3 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 VBB34630.1 - 2.4e-05 24.5 1.1 0.016 15.4 0.2 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 VBB34630.1 - 2.4e-05 23.8 1.4 0.0012 18.3 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 VBB34630.1 - 0.019 14.5 0.0 0.67 9.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 VBB34630.1 - 0.033 13.6 0.1 0.055 12.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein BAF250_C PF12031.8 VBB34630.1 - 0.036 13.4 0.1 0.057 12.7 0.1 1.2 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa RsgA_GTPase PF03193.16 VBB34630.1 - 0.063 13.2 0.3 15 5.4 0.1 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 VBB34630.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CTV_P33 PF07184.11 VBB34630.1 - 0.13 11.3 1.2 0.43 9.6 0.0 2.1 3 0 0 3 3 3 0 Citrus tristeza virus P33 protein MFS_1 PF07690.16 VBB34631.1 - 1.2e-14 54.0 11.5 1.2e-14 54.0 11.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB34631.1 - 1.1e-13 50.9 13.4 1.4e-13 50.6 13.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Whi5 PF08528.11 VBB34632.1 - 0.038 13.6 0.2 1.2e+02 2.4 0.0 4.4 4 0 0 4 4 4 0 Whi5 like ChW PF07538.11 VBB34632.1 - 0.73 9.8 7.0 2.2 8.3 0.3 3.4 1 1 1 2 2 2 0 Clostridial hydrophobic W COP-gamma_platf PF08752.10 VBB34633.1 - 3.2e-52 176.7 0.1 6.4e-52 175.7 0.1 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 VBB34633.1 - 2.1e-32 111.6 0.0 3.9e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Adaptin_N PF01602.20 VBB34633.1 - 5.6e-25 87.9 0.0 7.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 VBB34633.1 - 6.3e-08 32.9 0.1 1.2e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 VBB34633.1 - 0.0005 20.5 0.5 0.0014 19.1 0.5 1.8 1 0 0 1 1 1 1 HEAT-like repeat Cnd1 PF12717.7 VBB34633.1 - 0.011 15.8 0.1 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 VBB34633.1 - 0.02 15.5 0.8 0.084 13.6 0.4 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Coatomer_b_Cpla PF14806.6 VBB34633.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HEAT PF02985.22 VBB34633.1 - 0.16 12.3 3.7 12 6.5 0.4 3.2 3 0 0 3 3 3 0 HEAT repeat Glyco_hydro_18 PF00704.28 VBB34634.1 - 2.5e-17 63.6 0.0 2.9e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DAG_kinase_N PF14513.6 VBB34634.1 - 0.061 13.5 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF3145 PF11343.8 VBB34634.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) IFT46_B_C PF12317.8 VBB34636.1 - 8.6e-45 153.1 1.8 1e-44 152.8 1.8 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF5641 PF18701.1 VBB34637.1 - 2.5e-08 34.0 0.1 6.7e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5641) Mononeg_RNA_pol PF00946.19 VBB34638.1 - 0.012 13.3 1.5 0.013 13.1 1.5 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase zf-CCHC_4 PF14392.6 VBB34638.1 - 0.028 14.1 0.2 0.028 14.1 0.2 2.5 3 0 0 3 3 3 0 Zinc knuckle Exog_C PF18026.1 VBB34638.1 - 0.19 11.8 0.5 0.77 9.9 0.1 2.1 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Pkinase PF00069.25 VBB34640.1 - 5.7e-32 111.1 0.2 6.5e-32 110.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34640.1 - 2.3e-20 73.0 0.2 2.6e-20 72.8 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Mrpl_C PF18502.1 VBB34640.1 - 0.093 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain ATP-synt_D PF01813.17 VBB34641.1 - 9.7e-72 240.9 0.9 1.2e-71 240.6 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Adenine_glyco PF03352.13 VBB34641.1 - 0.36 10.6 2.4 0.27 11.0 0.3 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase CLASP_N PF12348.8 VBB34642.1 - 9.4e-13 48.2 0.6 9.4e-13 48.2 0.6 1.6 2 0 0 2 2 2 1 CLASP N terminal fn3 PF00041.21 VBB34643.1 - 1.3e-12 47.8 0.2 2.1e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_rec_like PF07699.13 VBB34643.1 - 9.6e-05 22.1 1.8 9.6e-05 22.1 1.8 3.3 2 1 1 3 3 3 2 Putative ephrin-receptor like fn3_2 PF16893.5 VBB34643.1 - 0.074 13.2 0.3 0.96 9.6 0.3 2.6 2 1 0 2 2 2 0 Fibronectin type III domain DUF4945 PF16303.5 VBB34643.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) NCD3G PF07562.14 VBB34643.1 - 3.4 7.7 10.2 22 5.1 4.0 3.2 2 1 1 3 3 3 0 Nine Cysteines Domain of family 3 GPCR IPP-2 PF04979.14 VBB34644.1 - 6.1e-06 27.0 2.5 0.04 14.7 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) HAD_2 PF13419.6 VBB34646.1 - 2.8e-21 76.4 0.0 3.4e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 VBB34646.1 - 2.7e-12 47.4 0.0 1.1e-11 45.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 VBB34646.1 - 0.0035 17.8 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 VBB34646.1 - 0.0063 16.6 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 VBB34646.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Nop14 PF04147.12 VBB34647.1 - 0.12 10.6 16.8 0.11 10.7 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 VBB34647.1 - 2.4 6.5 14.3 2.2 6.6 14.3 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 VBB34647.1 - 5.1 5.6 19.0 5.1 5.6 19.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 VBB34647.1 - 8.6 4.5 17.7 8 4.6 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 VBB34648.1 - 1.2e-14 54.0 11.5 1.2e-14 54.0 11.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 VBB34648.1 - 1.1e-13 50.9 13.4 1.4e-13 50.6 13.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter LRR_4 PF12799.7 VBB34650.1 - 2.8e-32 110.2 41.6 4.1e-07 30.2 5.3 7.6 2 2 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB34650.1 - 6.3e-24 84.4 24.6 2.4e-10 40.2 3.0 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 VBB34650.1 - 3.2e-19 68.4 34.3 1.7e-05 24.5 3.2 7.0 2 2 3 7 7 7 6 Leucine rich repeat LRR_6 PF13516.6 VBB34650.1 - 1.8e-08 33.8 20.2 0.63 10.2 0.2 8.2 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 VBB34650.1 - 0.0003 20.9 28.9 1.1 10.1 0.9 8.5 8 2 0 8 8 8 3 Leucine Rich Repeat Ribosomal_L50 PF10501.9 VBB34650.1 - 0.11 12.7 2.5 13 5.9 0.3 3.0 2 1 1 3 3 3 0 Ribosomal subunit 39S TM2 PF05154.16 VBB34651.1 - 0.66 10.4 5.5 1.6 9.1 5.4 1.8 1 1 0 1 1 1 0 TM2 domain MARVEL PF01284.23 VBB34651.1 - 1.3 9.0 14.6 2.1 8.4 14.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF4748 PF15932.5 VBB34651.1 - 8.5 6.2 6.3 17 5.2 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF2207 PF09972.9 VBB34651.1 - 8.6 5.0 7.6 24 3.5 7.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FGF PF00167.18 VBB34652.1 - 4e-18 65.7 1.0 8.1e-18 64.7 1.0 1.5 1 0 0 1 1 1 1 Fibroblast growth factor RVT_1 PF00078.27 VBB34653.1 - 5.7e-20 71.8 0.0 1.3e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 VBB34653.1 - 0.0006 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TTR-52 PF01060.23 VBB34655.1 - 1.6e-08 35.1 0.0 2.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Transthyretin-like family Lipid_DES PF08557.10 VBB34657.1 - 2.4e-18 65.3 0.1 4.9e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 VBB34657.1 - 1.6e-08 34.7 2.6 1.6e-08 34.7 2.6 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Aph-1 PF06105.12 VBB34659.1 - 2.9e-31 108.7 9.2 3.7e-31 108.3 9.2 1.1 1 0 0 1 1 1 1 Aph-1 protein CM2 PF03021.14 VBB34659.1 - 0.35 10.7 2.1 0.76 9.6 0.3 2.2 2 1 0 2 2 2 0 Influenza C virus M2 protein YoqO PF14037.6 VBB34659.1 - 1.3 9.6 4.8 0.57 10.7 1.7 1.9 2 1 0 2 2 2 0 YoqO-like protein uDENN PF03456.18 VBB34660.1 - 7.7e-20 71.4 0.3 1.8e-19 70.3 0.3 1.7 1 0 0 1 1 1 1 uDENN domain DENN PF02141.21 VBB34660.1 - 8.5e-20 71.5 3.5 3e-19 69.7 3.5 1.8 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 VBB34660.1 - 0.044 13.7 0.5 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 Stabilization of polarity axis SLC12 PF03522.15 VBB34661.1 - 2.9e-10 39.8 7.0 9.5e-06 24.9 6.3 3.0 1 1 1 2 2 2 2 Solute carrier family 12 DUF148 PF02520.17 VBB34663.1 - 0.00061 19.9 0.1 0.0009 19.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 DuoxA PF10204.9 VBB34664.1 - 3e-11 42.9 4.0 3.3e-11 42.7 4.0 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Osw5 PF17062.5 VBB34664.1 - 1.2 9.3 8.6 1.9 8.7 8.6 1.5 1 1 0 1 1 1 0 Outer spore wall 5 AMP-binding PF00501.28 VBB34665.1 - 5.7e-11 41.7 0.0 8.8e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ZapC PF07126.12 VBB34666.1 - 0.068 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Cell-division protein ZapC Patched PF02460.18 VBB34667.1 - 2.2e-37 128.6 17.3 4.2e-18 64.9 2.8 3.0 1 1 2 3 3 3 3 Patched family Sterol-sensing PF12349.8 VBB34667.1 - 2e-14 53.7 1.5 5.6e-14 52.2 1.5 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Aa_trans PF01490.18 VBB34670.1 - 9.8e-31 106.9 9.2 1.1e-30 106.7 9.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 VBB34670.1 - 0.00081 18.3 0.1 0.00081 18.3 0.1 2.7 2 1 1 3 3 3 1 Spore germination protein GPR_Gpa2_C PF11970.8 VBB34670.1 - 0.43 10.7 4.7 0.5 10.5 0.1 2.9 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term SUR7 PF06687.12 VBB34670.1 - 3.7 7.1 15.2 3.2 7.3 10.5 2.6 2 1 1 3 3 3 0 SUR7/PalI family DUF2070 PF09843.9 VBB34670.1 - 5.7 5.1 16.8 23 3.1 16.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) PAN_1 PF00024.26 VBB34672.1 - 4.1e-07 29.9 1.0 4.1e-07 29.9 1.0 3.1 3 0 0 3 3 3 1 PAN domain Mpp10 PF04006.12 VBB34672.1 - 0.00091 17.8 13.3 0.0012 17.5 13.3 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 VBB34672.1 - 0.00094 18.6 7.4 0.0012 18.3 7.4 1.2 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 VBB34672.1 - 0.002 17.7 12.8 0.0027 17.2 12.8 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 VBB34672.1 - 0.062 11.6 7.0 0.077 11.3 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 VBB34672.1 - 3.1 7.4 20.3 6.4 6.4 20.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Inhibitor_I29 PF08246.12 VBB34673.1 - 3.4e-06 27.4 1.0 3.4e-06 27.4 1.0 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Muted PF14942.6 VBB34673.1 - 0.0054 17.1 4.0 0.0071 16.7 3.5 1.4 1 1 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF349 PF03993.12 VBB34673.1 - 0.053 13.8 1.8 2.8 8.3 0.9 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Cytochrom_B562 PF07361.11 VBB34673.1 - 0.18 12.4 6.0 0.95 10.2 0.7 2.4 1 1 0 2 2 2 0 Cytochrome b562 Syntaxin_2 PF14523.6 VBB34673.1 - 0.4 11.1 2.6 1.9 8.9 0.1 2.4 1 1 1 2 2 2 0 Syntaxin-like protein SCVP PF17619.2 VBB34673.1 - 0.89 10.4 3.3 7.1 7.6 0.2 2.5 1 1 2 3 3 3 0 Secreted clade V proteins MIS13 PF08202.11 VBB34675.1 - 0.00038 19.8 7.0 0.00046 19.6 7.0 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family PB1 PF00564.24 VBB34675.1 - 0.01 15.7 0.1 0.061 13.3 0.1 2.1 2 0 0 2 2 2 0 PB1 domain TPR_MLP1_2 PF07926.12 VBB34675.1 - 0.3 11.1 16.3 0.038 14.0 3.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 VBB34675.1 - 0.69 10.4 13.9 0.87 10.1 1.0 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF5320 PF17253.2 VBB34675.1 - 0.88 10.7 4.0 14 6.8 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) FapA PF03961.13 VBB34675.1 - 0.93 8.0 14.1 0.85 8.1 3.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 VBB34675.1 - 0.96 9.0 5.7 1.3 8.6 5.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HNOBA PF07701.14 VBB34675.1 - 0.99 8.8 6.2 1 8.7 1.3 2.2 2 0 0 2 2 2 0 Heme NO binding associated DUF4140 PF13600.6 VBB34675.1 - 1.7 9.2 4.3 23 5.5 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Uso1_p115_C PF04871.13 VBB34675.1 - 2 8.8 15.1 3.4 8.0 3.2 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 VBB34675.1 - 4.9 6.4 13.9 1.1 8.5 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 VBB34675.1 - 6.1 7.4 9.4 4.3 7.9 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Syntaxin_2 PF14523.6 VBB34675.1 - 9.3 6.7 11.0 66 3.9 10.9 2.1 1 1 0 1 1 1 0 Syntaxin-like protein rve_2 PF13333.6 VBB34676.1 - 0.2 11.9 1.8 2.9 8.1 0.2 2.5 2 0 0 2 2 2 0 Integrase core domain DUF19 PF01579.18 VBB34679.1 - 3.9e-11 43.0 16.1 2.7e-10 40.3 6.4 3.6 3 1 1 4 4 4 3 Domain of unknown function (DUF19) DUF4364 PF14277.6 VBB34679.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) p450 PF00067.22 VBB34680.1 - 0.1 11.3 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Cytochrome P450 DNA_pol_E_B PF04042.16 VBB34681.1 - 6.1e-30 104.2 0.0 8.4e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 VBB34682.1 - 2.8e-17 63.0 0.0 3.6e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34682.1 - 1.8e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB34682.1 - 0.0004 19.3 0.0 0.00055 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 VBB34682.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coatomer_g_Cpla PF16381.5 VBB34683.1 - 2e-23 82.7 0.0 2.3e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF19 PF01579.18 VBB34684.1 - 5e-11 42.7 21.6 6.4e-09 35.8 5.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF19) COMM_domain PF07258.14 VBB34684.1 - 0.13 12.4 0.0 0.45 10.7 0.0 2.0 1 0 0 1 1 1 0 COMM domain zf-RING-like PF08746.11 VBB34684.1 - 0.18 12.1 3.7 2.4 8.5 0.0 3.1 2 1 0 2 2 2 0 RING-like domain Glycogen_syn PF05693.13 VBB34685.1 - 4.3e-154 514.5 0.0 5e-154 514.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 VBB34685.1 - 1.9e-05 24.3 0.0 4.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 VBB34685.1 - 5.6e-05 23.6 0.0 0.00058 20.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 MIR PF02815.19 VBB34686.1 - 5.7e-15 55.6 0.1 5.6e-13 49.1 0.0 2.5 1 1 1 3 3 3 3 MIR domain RicinB_lectin_2 PF14200.6 VBB34686.1 - 0.011 16.4 1.7 3 8.6 0.2 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DUF569 PF04601.13 VBB34686.1 - 0.034 13.8 0.2 0.58 9.8 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF569) CAP PF00188.26 VBB34687.1 - 0.0006 20.7 0.2 0.001 19.9 0.0 1.5 1 1 1 2 2 2 1 Cysteine-rich secretory protein family Abhydrolase_3 PF07859.13 VBB34688.1 - 4.1e-47 160.8 0.0 2.1e-35 122.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 VBB34688.1 - 3.6e-08 32.7 0.1 4.7e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 VBB34688.1 - 0.00058 18.9 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 VBB34688.1 - 0.095 12.2 0.1 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 VBB34688.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GreA_GreB_N PF03449.15 VBB34690.1 - 0.12 12.6 1.2 21 5.4 0.1 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal TMP_2 PF06791.13 VBB34690.1 - 3.2 7.4 8.1 0.46 10.1 0.2 2.7 2 1 1 3 3 3 0 Prophage tail length tape measure protein BCIP PF13862.6 VBB34691.1 - 7.5e-17 61.8 0.9 1.9e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 p21-C-terminal region-binding protein Neur_chan_LBD PF02931.23 VBB34692.1 - 6.4e-60 202.3 0.9 7.2e-60 202.1 0.9 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Homeobox_KN PF05920.11 VBB34693.1 - 0.0066 16.3 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Actin PF00022.19 VBB34694.1 - 1.1e-96 324.0 0.0 4.4e-96 322.0 0.0 1.7 1 1 0 1 1 1 1 Actin 7tm_1 PF00001.21 VBB34695.1 - 2.7e-13 49.8 19.9 3.3e-07 29.9 8.1 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) TRSP PF12500.8 VBB34695.1 - 0.094 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 Collagen PF01391.18 VBB34696.1 - 3.5e-10 39.5 37.5 7.5e-10 38.4 37.5 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) SARAF PF06682.12 VBB34696.1 - 0.095 12.3 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis zf-CCCH PF00642.24 VBB34697.1 - 0.00023 21.0 2.8 0.00023 21.0 2.8 1.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 VBB34697.1 - 0.0035 17.1 1.8 0.0069 16.2 1.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 VBB34697.1 - 0.047 13.7 4.7 0.047 13.7 4.7 1.5 2 0 0 2 2 2 0 Zinc finger domain DUF3331 PF11811.8 VBB34697.1 - 0.13 12.2 0.9 0.31 10.9 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3331) ATAD4 PF15321.6 VBB34698.1 - 0.0098 17.2 14.4 0.0098 17.2 14.4 3.0 3 1 0 3 3 3 1 ATPase family AAA domain containing 4 PTPRCAP PF15713.5 VBB34698.1 - 0.61 10.4 17.1 1.1 9.6 17.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PAT1 PF09770.9 VBB34698.1 - 0.93 7.7 29.7 1.2 7.3 29.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 VBB34698.1 - 1.2 7.8 22.0 1.9 7.2 22.0 1.3 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 VBB34698.1 - 2.5 6.8 15.7 3.7 6.2 15.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PepSY_TM PF03929.16 VBB34698.1 - 2.8 7.6 7.0 3.7 7.1 7.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region TMEM51 PF15345.6 VBB34698.1 - 4.3 7.1 17.6 7.9 6.2 17.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Connexin PF00029.19 VBB34698.1 - 4.5 7.0 12.3 7.7 6.2 12.3 1.4 1 0 0 1 1 1 0 Connexin SUFU_C PF12470.8 VBB34698.1 - 8.9 6.3 13.7 21 5.1 13.7 1.6 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain CBM_14 PF01607.24 VBB34699.1 - 6.7e-11 42.2 3.3 1e-10 41.6 3.3 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 VBB34699.1 - 2.2e-08 34.2 1.1 2.9e-08 33.8 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase_Tyr PF07714.17 VBB34700.1 - 6.5e-70 235.4 0.0 7.7e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB34700.1 - 2.2e-39 135.4 0.0 5e-24 85.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 VBB34700.1 - 2.7e-05 24.2 0.0 0.00013 22.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 VBB34700.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FHA_2 PF17913.1 VBB34700.1 - 0.019 15.2 0.1 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 FHA domain Kdo PF06293.14 VBB34700.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 VBB34700.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 VBB34700.1 - 0.14 11.7 0.2 0.7 9.5 0.0 2.1 2 1 0 2 2 2 0 RIO1 family Neur_chan_LBD PF02931.23 VBB34701.1 - 4e-25 88.5 0.0 4.5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Acyl-CoA_dh_M PF02770.19 VBB34702.1 - 3.2e-08 33.7 0.0 5.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Zea_mays_MuDR PF05928.11 VBB34703.1 - 0.017 14.7 2.6 0.18 11.4 1.3 2.2 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) Glyco_hydro_115 PF15979.5 VBB34703.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 UCMA PF17085.5 VBB34704.1 - 0.0091 16.0 3.7 0.011 15.8 3.7 1.1 1 0 0 1 1 1 1 Unique cartilage matrix associated protein NUMOD4 PF07463.11 VBB34704.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 NUMOD4 motif DUF3552 PF12072.8 VBB34704.1 - 0.12 11.8 7.5 0.13 11.7 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CDP-OH_P_transf PF01066.21 VBB34705.1 - 1e-16 61.4 0.2 1e-16 61.4 0.2 3.4 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Metallophos PF00149.28 VBB34707.1 - 2.2e-35 123.0 0.2 2.8e-35 122.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MAGI_u1 PF16663.5 VBB34708.1 - 0.11 12.6 1.5 5.1 7.2 0.4 2.8 2 0 0 2 2 2 0 Unstructured region on MAGI DUF148 PF02520.17 VBB34710.1 - 1.3e-05 25.3 7.0 2.4e-05 24.4 6.8 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF148 GldM_N PF12081.8 VBB34710.1 - 0.0085 16.2 6.5 0.01 15.9 6.5 1.2 1 0 0 1 1 1 1 GldM N-terminal domain Drf_GBD PF06371.13 VBB34710.1 - 0.18 11.4 7.9 0.23 11.0 7.9 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain CotJB PF12652.7 VBB34710.1 - 0.27 11.5 2.3 0.42 10.9 1.6 1.7 1 1 0 1 1 1 0 CotJB protein AD PF09793.9 VBB34710.1 - 0.31 11.2 5.6 1.4 9.1 4.4 2.3 1 1 1 2 2 2 0 Anticodon-binding domain DUF4230 PF14014.6 VBB34710.1 - 0.44 10.8 6.7 0.71 10.1 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) 5_nucleotid PF05761.14 VBB34710.1 - 0.47 9.3 8.3 0.53 9.1 8.3 1.1 1 0 0 1 1 1 0 5' nucleotidase family FapA PF03961.13 VBB34710.1 - 4.3 5.8 10.5 5 5.6 10.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Metallophos PF00149.28 VBB34711.1 - 5.8e-05 23.7 0.0 9.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Frag1 PF10277.9 VBB34714.1 - 0.00021 20.9 2.9 0.00027 20.5 2.9 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family zf-H2C2_5 PF13909.6 VBB34715.1 - 0.00018 21.2 0.9 0.00018 21.2 0.9 6.4 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 VBB34715.1 - 0.033 14.6 0.8 0.033 14.6 0.8 6.2 6 0 0 6 6 6 0 Zinc-finger double domain CIAPIN1 PF05093.13 VBB34715.1 - 0.19 12.3 0.2 0.19 12.3 0.2 3.4 3 2 0 4 4 4 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3449 PF11931.8 VBB34716.1 - 3.6e-74 248.5 0.1 4e-74 248.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 VBB34716.1 - 0.018 15.9 0.1 0.037 14.8 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 VBB34716.1 - 0.097 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type NARG2_C PF10505.9 VBB34717.1 - 4e-22 78.8 0.0 5.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Collagen PF01391.18 VBB34718.1 - 7.7e-15 54.4 69.6 6.6e-09 35.4 33.8 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB34719.1 - 2.3e-14 52.9 63.8 3.6e-08 33.0 31.2 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CCT_2 PF09425.10 VBB34720.1 - 0.27 11.2 1.1 11 6.0 0.3 2.2 2 0 0 2 2 2 0 Divergent CCT motif Nop14 PF04147.12 VBB34720.1 - 1.9 6.6 36.5 2.3 6.4 36.5 1.0 1 0 0 1 1 1 0 Nop14-like family BORG_CEP PF14957.6 VBB34720.1 - 2 9.6 11.0 2.9 9.1 11.0 1.3 1 0 0 1 1 1 0 Cdc42 effector rRNA_processing PF08524.11 VBB34720.1 - 2.7 8.0 32.2 3.1 7.8 32.2 1.1 1 0 0 1 1 1 0 rRNA processing RR_TM4-6 PF06459.12 VBB34720.1 - 3 7.6 28.2 3.5 7.4 28.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 VBB34720.1 - 3.1 6.7 16.6 3.6 6.5 16.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 VBB34720.1 - 3.2 6.4 18.7 3.9 6.2 18.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cupin_8 PF13621.6 VBB34720.1 - 3.8 7.2 9.9 5.1 6.7 9.9 1.3 1 0 0 1 1 1 0 Cupin-like domain DDRGK PF09756.9 VBB34720.1 - 5.3 6.6 44.3 7.6 6.1 44.3 1.2 1 0 0 1 1 1 0 DDRGK domain Endostatin PF06482.11 VBB34720.1 - 6.2 6.2 7.1 6.2 6.2 7.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 VBB34720.1 - 8.3 4.4 19.3 9 4.3 19.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 VBB34720.1 - 8.6 6.3 9.8 10 6.1 9.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC27 PF09507.10 VBB34720.1 - 8.9 5.6 35.8 10 5.3 35.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 fn3 PF00041.21 VBB34721.1 - 7.1e-17 61.5 4.8 1.5e-09 38.1 0.1 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.10 VBB34721.1 - 1e-05 25.7 0.1 0.012 16.0 0.2 2.3 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 VBB34721.1 - 0.0012 19.4 4.6 0.58 10.8 0.4 2.8 2 2 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 VBB34721.1 - 0.02 15.3 0.1 0.27 11.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Cofilin_ADF PF00241.20 VBB34721.1 - 0.021 14.6 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein DUF1410 PF07198.11 VBB34721.1 - 0.75 10.3 4.9 8.2 7.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1410) Glyco_transf_43 PF03360.16 VBB34722.1 - 2.4e-64 216.9 0.0 3.4e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 FTCD_C PF04961.12 VBB34724.1 - 0.023 14.5 2.1 0.085 12.6 0.2 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase RasGEF_N PF00618.20 VBB34725.1 - 0.0027 17.9 0.1 0.011 15.9 0.1 2.0 1 1 0 1 1 1 1 RasGEF N-terminal motif RGS PF00615.19 VBB34726.1 - 4.8e-16 59.1 0.4 5.3e-16 59.0 0.4 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gaa1 PF04114.14 VBB34727.1 - 7.1e-54 183.6 0.7 1.1e-53 183.0 0.7 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component U3snoRNP10 PF12397.8 VBB34727.1 - 0.057 13.8 0.5 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Sugar_tr PF00083.24 VBB34729.1 - 7.9e-10 38.2 4.2 7.9e-10 38.2 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 VBB34729.1 - 6.8e-09 35.1 3.9 9.3e-09 34.7 3.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 VBB34729.1 - 0.8 10.1 4.6 0.22 11.9 1.6 1.6 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V NicO PF03824.16 VBB34731.1 - 0.21 10.9 4.2 0.24 10.7 2.5 1.7 1 1 1 2 2 2 0 High-affinity nickel-transport protein Sporozoite_P67 PF05642.11 VBB34734.1 - 0.0053 14.9 1.2 0.0064 14.6 1.2 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 VBB34734.1 - 0.026 14.9 3.9 0.038 14.4 3.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 VBB34734.1 - 0.21 10.9 6.2 0.27 10.5 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 VBB34734.1 - 4 6.5 9.4 5.2 6.1 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) C1_1 PF00130.22 VBB34735.1 - 9.8e-20 70.2 31.3 2e-12 46.8 14.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB34735.1 - 4.7e-05 23.6 23.2 0.0014 18.9 4.6 2.4 2 0 0 2 2 2 2 C1 domain PHD PF00628.29 VBB34735.1 - 0.00016 21.5 8.7 0.00016 21.5 8.7 2.7 2 1 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 VBB34735.1 - 0.0098 16.0 5.0 0.0098 16.0 5.0 2.2 2 0 0 2 2 2 2 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 VBB34735.1 - 3.4 7.4 28.8 6.1 6.6 8.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C4 PF00105.18 VBB34737.1 - 1.4e-08 35.1 4.9 2.2e-08 34.4 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) HopJ PF08888.11 VBB34737.1 - 0.17 12.1 0.6 0.51 10.6 0.4 1.8 1 1 1 2 2 2 0 HopJ type III effector protein TPR_MLP1_2 PF07926.12 VBB34738.1 - 3.2e-05 24.0 59.8 0.00051 20.1 7.0 5.1 3 2 1 4 4 4 3 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 VBB34738.1 - 0.0044 16.9 2.1 0.0044 16.9 2.1 6.6 5 2 2 7 7 7 2 GIT coiled-coil Rho guanine nucleotide exchange factor ERM PF00769.19 VBB34738.1 - 0.0093 15.8 60.1 0.34 10.7 17.7 2.5 1 1 1 2 2 2 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 VBB34738.1 - 0.013 15.5 24.9 0.013 15.5 24.9 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.12 VBB34738.1 - 0.07 13.4 0.6 0.07 13.4 0.6 4.3 3 2 1 5 5 5 0 Proteins of 100 residues with WXG Zw10 PF06248.13 VBB34738.1 - 0.19 10.3 25.3 0.0056 15.3 15.5 2.2 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 Halo_GVPC PF05465.13 VBB34738.1 - 0.2 11.9 0.3 0.2 11.9 0.3 3.6 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat KASH_CCD PF14662.6 VBB34738.1 - 0.32 10.8 66.9 0.19 11.5 25.1 4.5 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 VBB34738.1 - 0.63 9.4 63.6 0.25 10.8 20.1 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 GAS PF13851.6 VBB34738.1 - 0.73 9.2 64.8 0.32 10.3 22.1 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.12 VBB34738.1 - 1.2 8.6 43.8 2.9 7.4 2.6 3.6 2 2 1 3 3 3 0 PspA/IM30 family Lebercilin PF15619.6 VBB34738.1 - 1.3 8.7 66.1 2.4 7.8 22.8 4.1 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 VBB34738.1 - 2.3 8.3 63.0 0.17 12.0 4.8 3.9 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 VBB34738.1 - 4.1 6.8 56.4 0.88 9.0 18.4 3.4 1 1 1 3 3 3 0 Leucine zipper FlaC_arch PF05377.11 VBB34738.1 - 6.5 7.2 40.1 8.9 6.8 2.3 6.9 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) zf-C4 PF00105.18 VBB34740.1 - 2.7e-12 46.9 5.5 2.7e-12 46.9 5.5 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) MHC_I PF00129.18 VBB34741.1 - 0.073 12.6 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Haspin_kinase PF12330.8 VBB34743.1 - 3e-32 112.0 3.1 4.2e-32 111.5 3.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain PDZ PF00595.24 VBB34744.1 - 6.7e-16 58.4 0.4 1.3e-15 57.5 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB34744.1 - 1.8e-09 37.3 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB34744.1 - 0.00041 20.6 0.1 0.00079 19.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain MapZ_EC1 PF18041.1 VBB34747.1 - 0.016 15.5 1.9 0.079 13.2 1.9 2.2 1 0 0 1 1 1 0 MapZ extracellular domain 1 Baculo_PEP_C PF04513.12 VBB34747.1 - 0.07 13.2 3.1 1.7 8.7 0.2 2.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4239 PF14023.6 VBB34747.1 - 0.091 12.5 1.0 3.7 7.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Phasin PF05597.11 VBB34747.1 - 0.19 11.7 1.9 19 5.3 0.2 3.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SF-assemblin PF06705.11 VBB34747.1 - 0.44 9.9 16.4 0.83 8.9 0.5 3.9 2 1 2 4 4 4 0 SF-assemblin/beta giardin RasGAP_C PF03836.15 VBB34747.1 - 2.2 8.4 8.1 2.8 8.1 0.5 3.2 3 0 0 3 3 3 0 RasGAP C-terminus HrcA PF01628.21 VBB34747.1 - 2.5 8.0 6.0 1.4 8.8 0.4 2.7 2 1 1 3 3 3 0 HrcA protein C terminal domain Swi5 PF07061.11 VBB34747.1 - 7.7 6.7 11.5 2.8 8.1 0.5 3.9 4 0 0 4 4 4 0 Swi5 LRR_4 PF12799.7 VBB34748.1 - 9e-10 38.7 9.9 0.0037 17.6 0.2 4.7 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 VBB34748.1 - 1.2e-07 31.1 15.8 0.0029 17.5 0.4 5.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 VBB34748.1 - 0.00023 21.2 13.8 19 6.3 1.8 6.9 6 1 1 7 7 7 2 Leucine Rich Repeat Sushi PF00084.20 VBB34749.1 - 1e-14 54.9 8.8 2.1e-05 25.0 0.1 3.5 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) Furin-like_2 PF15913.5 VBB34751.1 - 0.023 14.8 1.0 0.048 13.8 0.4 1.8 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich 7TM_GPCR_Srw PF10324.9 VBB34752.1 - 1.5e-12 47.4 14.8 1.9e-12 47.1 14.8 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 VBB34752.1 - 1.3e-09 37.8 12.5 1.9e-09 37.2 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFP2b PF12150.8 VBB34753.1 - 2.1e-19 70.1 0.4 2.5e-19 69.8 0.4 1.0 1 0 0 1 1 1 1 Cytosolic motility protein Spin-Ssty PF02513.17 VBB34753.1 - 0.032 13.9 0.7 0.049 13.4 0.1 1.5 2 0 0 2 2 2 0 Spin/Ssty Family LPD22 PF18834.1 VBB34753.1 - 0.18 12.1 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 ArAE_2_N PF10337.9 VBB34754.1 - 0.44 9.5 1.0 0.47 9.4 1.0 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CAP PF00188.26 VBB34755.1 - 4.8e-08 33.9 2.2 6.6e-08 33.5 2.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PBP1_TM PF14812.6 VBB34758.1 - 0.71 10.3 15.5 0.67 10.4 15.5 1.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 VBB34758.1 - 3.8 7.9 15.6 3.6 8.0 15.6 1.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MBOAT PF03062.19 VBB34760.1 - 9.3e-16 58.1 4.4 1.3e-15 57.7 4.4 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CoA_binding_3 PF13727.6 VBB34760.1 - 3.3 7.7 10.0 0.45 10.5 0.7 2.1 1 1 1 2 2 2 0 CoA-binding domain Neur_chan_memb PF02932.16 VBB34762.1 - 8.8e-31 107.8 4.1 1.1e-30 107.5 4.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 VBB34762.1 - 3e-18 66.1 0.1 1e-17 64.4 0.0 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1634 PF07843.11 VBB34762.1 - 0.0017 18.4 1.3 0.0017 18.4 1.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1634) LRR_8 PF13855.6 VBB34763.1 - 2.7e-18 65.5 27.6 5.4e-07 29.3 1.9 4.5 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 VBB34763.1 - 3.1e-11 43.3 32.6 0.00011 22.4 1.9 5.7 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 VBB34763.1 - 7e-06 25.7 11.7 0.0031 17.1 5.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 VBB34763.1 - 0.00013 21.8 15.4 5.7 7.3 0.0 7.3 8 1 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 VBB34763.1 - 0.0043 17.4 26.5 7.5 7.5 0.2 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat Ank_2 PF12796.7 VBB34764.1 - 1.7e-23 83.0 2.0 2.4e-12 47.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB34764.1 - 5.8e-18 64.7 6.4 2.2e-05 24.6 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 VBB34764.1 - 8.9e-17 60.7 9.0 3.1e-05 24.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 VBB34764.1 - 2.8e-15 56.5 5.0 0.00015 22.3 0.0 5.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB34764.1 - 1.2e-14 52.9 10.8 0.037 14.6 0.1 6.3 6 1 0 6 6 6 4 Ankyrin repeat BORCS8 PF10167.9 VBB34764.1 - 0.024 14.6 0.1 0.084 12.8 0.1 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 Cep57_CLD_2 PF14197.6 VBB34765.1 - 0.00077 19.5 5.0 0.00077 19.5 5.0 5.9 4 2 1 5 5 5 1 Centrosome localisation domain of PPC89 DUF4349 PF14257.6 VBB34765.1 - 0.0018 17.7 2.5 0.0018 17.7 2.5 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4349) HOOK PF05622.12 VBB34765.1 - 0.24 9.5 55.3 0.65 8.1 36.7 2.4 1 1 1 2 2 2 0 HOOK protein YbbR PF07949.12 VBB34765.1 - 0.71 10.3 2.1 1.7 9.0 1.3 2.2 2 1 0 2 2 2 0 YbbR-like protein Filamin PF00630.19 VBB34766.1 - 3.6e-08 34.2 0.1 4.7e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Filamin/ABP280 repeat PapC_N PF13954.6 VBB34766.1 - 0.022 14.8 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 PapC N-terminal domain ER PF01133.17 VBB34767.1 - 3e-42 142.6 0.2 3.4e-42 142.4 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary 7TM_GPCR_Srt PF10321.9 VBB34768.1 - 0.0023 16.9 2.1 0.0028 16.7 2.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF3995 PF13160.6 VBB34768.1 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3995) DUF805 PF05656.14 VBB34768.1 - 0.049 14.0 0.3 0.066 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Presenilin PF01080.17 VBB34768.1 - 0.22 10.2 3.6 0.27 9.9 3.6 1.1 1 0 0 1 1 1 0 Presenilin His_Phos_2 PF00328.22 VBB34769.1 - 3.8e-05 23.2 0.1 0.00015 21.3 0.1 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 VBB34770.1 - 1.6e-13 50.6 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain 7tm_3 PF00003.22 VBB34771.1 - 2e-17 63.8 5.1 2.5e-17 63.4 5.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR TctB PF07331.11 VBB34771.1 - 0.23 11.7 5.6 0.56 10.5 5.5 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Saf_2TM PF18303.1 VBB34771.1 - 2 8.0 4.8 37 3.9 4.3 2.5 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Chloroplast_duf PF14476.6 VBB34772.1 - 0.26 10.2 3.6 0.27 10.2 3.6 1.0 1 0 0 1 1 1 0 Petal formation-expressed FAM199X PF15814.5 VBB34772.1 - 5.1 6.0 8.2 6 5.8 8.2 1.1 1 0 0 1 1 1 0 Protein family FAM199X G2BR PF18442.1 VBB34773.1 - 0.0048 16.5 0.1 0.0089 15.6 0.1 1.4 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) DUF2639 PF11121.8 VBB34773.1 - 0.025 14.6 0.9 0.035 14.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) ELFV_dehydrog PF00208.21 VBB34774.1 - 3e-27 95.9 0.0 1.3e-23 84.1 0.0 2.0 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 VBB34774.1 - 0.14 9.6 0.0 0.18 9.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase MFS_1 PF07690.16 VBB34775.1 - 6.1e-20 71.4 7.7 8e-20 71.1 7.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily EpuA PF11772.8 VBB34775.1 - 0.05 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PUCC PF03209.15 VBB34775.1 - 0.12 11.3 5.7 0.19 10.7 5.7 1.2 1 0 0 1 1 1 0 PUCC protein DUF3509 PF12021.8 VBB34776.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Retrotrans_gag PF03732.17 VBB34776.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH PF17917.1 VBB34777.1 - 4.4e-32 110.5 0.0 7.4e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 VBB34777.1 - 2.9e-31 107.4 0.0 6.4e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 VBB34777.1 - 3.2e-24 85.7 0.1 9.7e-24 84.1 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 VBB34777.1 - 6e-11 42.3 0.1 1.2e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB34777.1 - 0.0024 18.0 1.2 0.0074 16.5 0.8 2.0 2 0 0 2 2 2 1 H2C2 zinc finger RhoGEF PF00621.20 VBB34778.1 - 8.5e-12 45.7 1.0 1.4e-11 45.0 1.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 VBB34778.1 - 2.7e-06 27.0 0.0 6.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB34778.1 - 0.00043 19.8 0.2 0.003 17.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 VBB34778.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Mac PF12464.8 VBB34778.1 - 0.099 12.9 1.0 5.8 7.2 0.4 2.9 3 0 0 3 3 3 0 Maltose acetyltransferase DUF1542 PF07564.11 VBB34778.1 - 0.13 12.3 1.4 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Collagen PF01391.18 VBB34779.1 - 9.1e-08 31.7 57.6 6.5e-05 22.6 57.6 2.3 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ig_3 PF13927.6 VBB34780.1 - 2.1e-09 37.9 0.7 3.2e-09 37.3 0.7 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 VBB34780.1 - 2.3e-06 27.5 0.2 3.4e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 VBB34780.1 - 2.7e-06 27.6 0.6 6.7e-06 26.4 0.6 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 VBB34780.1 - 3.9e-06 26.9 0.1 5.2e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 VBB34780.1 - 3.5e-05 23.8 0.1 5.7e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain YscW PF09619.10 VBB34780.1 - 0.2 12.0 0.0 0.39 11.1 0.0 1.5 1 1 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) Thioredoxin_8 PF13905.6 VBB34781.1 - 1.6e-18 66.8 0.0 1.9e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 VBB34781.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin PF00085.20 VBB34781.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin ANAPC4_WD40 PF12894.7 VBB34782.1 - 0.01 16.1 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain START PF01852.19 VBB34783.1 - 6.4e-14 51.9 0.0 1e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 START domain RYDR_ITPR PF01365.21 VBB34786.1 - 4.8e-51 173.1 0.3 9.2e-51 172.1 0.1 1.6 2 0 0 2 2 2 1 RIH domain MIR PF02815.19 VBB34786.1 - 1.4e-34 119.6 0.0 2.2e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF5354 PF17305.2 VBB34787.1 - 0.088 13.0 1.9 0.11 12.7 0.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5354) ELM2 PF01448.24 VBB34788.1 - 3.2e-05 24.6 0.6 5.2e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 ELM2 domain Lipase_2 PF01674.18 VBB34789.1 - 5.2e-48 163.4 0.1 6.2e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 VBB34789.1 - 0.038 13.8 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 VBB34789.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Collagen PF01391.18 VBB34790.1 - 2.3e-55 184.2 176.4 4e-10 39.3 21.7 7.1 5 2 2 7 7 7 7 Collagen triple helix repeat (20 copies) OLF PF02191.16 VBB34791.1 - 1.9e-21 76.8 0.1 2e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain AKAP7_NLS PF10469.9 VBB34792.1 - 5.4e-47 160.4 0.6 6.3e-47 160.2 0.6 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain HVSL PF09749.9 VBB34792.1 - 4.9e-05 22.9 0.1 6.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 VBB34792.1 - 0.00042 20.3 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 VBB34792.1 - 0.0066 16.6 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 2 LigT like Phosphoesterase UPF0253 PF06786.12 VBB34792.1 - 0.011 16.0 0.0 6 7.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) EFF-AFF PF14884.6 VBB34793.1 - 1.8e-17 62.7 0.0 1.9e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen PHD PF00628.29 VBB34795.1 - 1.7e-18 66.2 31.9 7.7e-11 41.7 8.8 3.1 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.6 VBB34795.1 - 9.6e-05 21.9 19.4 0.0047 16.5 1.2 4.0 4 0 0 4 4 4 2 PHD-finger PHF12_MRG_bd PF16737.5 VBB34795.1 - 0.0002 21.0 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain C1_1 PF00130.22 VBB34795.1 - 0.00039 20.3 18.3 0.0035 17.2 2.4 3.5 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 VBB34795.1 - 0.0034 17.6 16.0 0.31 11.3 5.5 2.8 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 VBB34795.1 - 0.0087 16.2 11.6 0.61 10.3 0.7 2.8 2 0 0 2 2 2 2 PHD-zinc-finger like domain TTSSLRR PF12468.8 VBB34795.1 - 0.028 14.6 0.0 0.089 13.0 0.0 1.9 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Zf_RING PF16744.5 VBB34795.1 - 0.035 14.2 1.3 0.035 14.2 1.3 2.9 3 0 0 3 3 3 0 KIAA1045 RING finger zf-PHD-like PF15446.6 VBB34795.1 - 0.98 9.0 21.5 0.046 13.3 4.3 3.7 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain PAS_3 PF08447.12 VBB34796.1 - 6.6e-13 48.8 0.2 2e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 VBB34796.1 - 1.8e-11 44.2 0.4 4.5e-08 33.2 0.1 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 VBB34796.1 - 4e-10 39.7 0.0 4.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 VBB34796.1 - 7.7e-05 22.9 0.0 0.00027 21.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 VBB34796.1 - 0.028 14.7 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF1759 PF03564.15 VBB34797.1 - 1.9e-10 40.9 1.0 5.3e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1759) Ly49 PF08391.10 VBB34797.1 - 9.1 6.7 14.7 3.3 8.1 0.1 3.0 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Guanylate_cyc PF00211.20 VBB34798.1 - 1.9e-59 200.4 0.5 2.2e-59 200.2 0.5 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kinase-PPPase PF03618.14 VBB34798.1 - 0.069 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Kinase/pyrophosphorylase SH3_1 PF00018.28 VBB34800.1 - 4.1e-16 58.3 0.1 8e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Myosin_TH1 PF06017.13 VBB34800.1 - 7.1e-15 55.2 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 VBB34800.1 - 2.1e-14 53.1 0.0 3.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB34800.1 - 1.3e-10 40.8 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain LIN52 PF10044.9 VBB34801.1 - 0.12 13.1 0.7 1 10.1 0.0 2.7 3 0 0 3 3 3 0 Retinal tissue protein zf-C2H2_6 PF13912.6 VBB34801.1 - 0.4 10.7 0.1 0.4 10.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TT_ORF2 PF02957.15 VBB34801.1 - 0.55 11.2 3.8 0.38 11.7 1.0 2.2 2 1 0 2 2 2 0 TT viral ORF2 zf-C2H2_4 PF13894.6 VBB34801.1 - 0.57 11.2 16.7 2.3 9.3 2.6 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Amnionless PF14828.6 VBB34802.1 - 1e-12 47.7 0.0 1.1e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Amnionless DM13 PF10517.9 VBB34804.1 - 3e-14 53.4 0.4 2.8e-07 31.1 0.1 3.3 3 0 0 3 3 3 2 Electron transfer DM13 Tubulin_C PF03953.17 VBB34804.1 - 0.038 14.2 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin C-terminal domain Myosin_head PF00063.21 VBB34805.1 - 6.9e-155 517.0 0.4 7.8e-155 516.8 0.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 VBB34805.1 - 2.1e-13 49.9 0.3 4.1e-13 48.9 0.3 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.6 VBB34805.1 - 0.03 14.6 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 VBB34805.1 - 0.054 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 VBB34805.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PEHE PF15275.6 VBB34805.1 - 0.11 13.2 0.1 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 PEHE domain Rieske PF00355.26 VBB34806.1 - 1.4e-16 60.2 0.0 2.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 VBB34806.1 - 2.1e-08 34.1 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain RGS PF00615.19 VBB34807.1 - 0.019 15.3 1.3 0.74 10.1 0.1 2.5 2 1 0 2 2 2 0 Regulator of G protein signaling domain TPR_12 PF13424.6 VBB34808.1 - 2e-10 40.8 6.7 0.00015 22.0 0.1 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 VBB34808.1 - 2.4e-09 36.6 10.8 0.14 12.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 VBB34808.1 - 1.3e-08 34.4 1.3 0.0015 18.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 VBB34808.1 - 0.00036 21.0 0.9 0.13 12.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 VBB34808.1 - 0.00053 19.7 15.4 1.1 9.2 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 VBB34808.1 - 0.00058 19.7 11.7 0.63 10.2 0.1 5.9 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 VBB34808.1 - 0.0021 18.6 1.6 27 5.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 VBB34808.1 - 0.0032 16.9 2.4 0.26 10.6 0.1 2.8 2 1 1 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 VBB34808.1 - 0.0046 17.1 14.1 0.56 10.6 0.0 6.6 7 2 2 9 9 9 2 Tetratricopeptide repeat Collagen PF01391.18 VBB34809.1 - 1.3e-10 40.8 39.5 7.9e-10 38.4 38.0 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) EF-hand_7 PF13499.6 VBB34810.1 - 2.5e-05 24.6 4.4 0.00017 22.0 2.4 2.4 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 VBB34810.1 - 3e-05 23.6 5.2 0.017 15.0 0.7 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 VBB34810.1 - 0.0018 17.7 7.1 0.011 15.2 0.5 3.6 3 2 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 VBB34810.1 - 0.002 17.5 4.4 0.079 12.5 0.3 3.3 3 0 0 3 3 3 2 EF hand LBP_BPI_CETP PF01273.25 VBB34812.1 - 0.01 15.5 0.9 0.48 10.0 0.0 2.7 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain HTH_Mga PF08280.11 VBB34812.1 - 0.054 13.5 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain SH2 PF00017.24 VBB34814.1 - 6.9e-05 22.9 0.0 0.00035 20.6 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Peptidase_A17 PF05380.13 VBB34816.1 - 1e-38 132.9 0.7 1.3e-38 132.6 0.7 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase ATLF PF07737.11 VBB34817.1 - 0.075 12.3 0.5 0.13 11.6 0.5 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Neur_chan_LBD PF02931.23 VBB34818.1 - 4.2e-11 42.7 0.3 5e-11 42.5 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain G6PD_N PF00479.22 VBB34819.1 - 0.0011 19.7 0.2 0.0011 19.7 0.2 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain EF-hand_10 PF14788.6 VBB34819.1 - 0.06 13.2 1.4 0.13 12.2 0.2 2.2 2 0 0 2 2 2 0 EF hand LOH1CR12 PF10158.9 VBB34819.1 - 0.18 11.8 1.0 0.71 9.9 0.0 2.4 3 0 0 3 3 3 0 Tumour suppressor protein Tubulin_C PF03953.17 VBB34820.1 - 4.6e-41 139.9 0.0 7.2e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 VBB34820.1 - 2.7e-07 31.0 0.1 5.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain EGF_2 PF07974.13 VBB34821.1 - 0.064 13.6 16.4 1.8 9.0 3.8 3.6 3 1 0 3 3 3 0 EGF-like domain Death PF00531.22 VBB34825.1 - 7.7e-06 26.0 0.0 8.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Death domain DUF4384 PF14326.6 VBB34825.1 - 0.21 11.7 0.0 4.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) FARP PF01581.16 VBB34826.1 - 9.4e-09 34.3 38.9 0.65 10.7 1.0 7.7 9 0 0 9 9 9 6 FMRFamide related peptide family KRTDAP PF15200.6 VBB34826.1 - 0.044 13.6 0.4 0.25 11.2 0.1 2.3 1 1 2 3 3 3 0 Keratinocyte differentiation-associated fn3 PF00041.21 VBB34827.1 - 2.5e-05 24.5 0.1 6.8e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Fibronectin type III domain Y_Y_Y PF07495.13 VBB34827.1 - 0.014 15.3 0.2 0.078 12.9 0.1 1.9 1 1 1 2 2 2 0 Y_Y_Y domain zf-LITAF-like PF10601.9 VBB34829.1 - 5.5e-08 33.0 1.6 7.5e-08 32.5 1.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain TMEM215 PF15746.5 VBB34829.1 - 0.044 13.2 0.4 0.065 12.7 0.4 1.2 1 0 0 1 1 1 0 TMEM215 family CAP PF00188.26 VBB34830.1 - 1.7e-12 48.3 0.1 2.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Squash PF00299.18 VBB34830.1 - 6.6 6.8 7.5 2.7 8.1 4.8 1.7 2 0 0 2 2 2 0 Squash family serine protease inhibitor Pkinase PF00069.25 VBB34831.1 - 7.1e-33 114.1 0.0 9.2e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34831.1 - 2.4e-13 50.0 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TMP_2 PF06791.13 VBB34831.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein Zip PF02535.22 VBB34832.1 - 1.3e-11 44.3 9.8 1.4e-07 31.1 2.1 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter PS_pyruv_trans PF04230.13 VBB34832.1 - 0.063 13.2 0.1 0.069 13.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Pkinase PF00069.25 VBB34833.1 - 1.5e-27 96.6 0.2 3.1e-27 95.6 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB34833.1 - 8.5e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 VBB34833.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family F-box PF00646.33 VBB34834.1 - 0.0043 16.9 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 VBB34834.1 - 0.078 12.8 0.1 1.7 8.5 0.0 2.8 2 1 0 2 2 2 0 Leucine rich repeat MIF4G PF02854.19 VBB34835.1 - 2.4e-08 33.9 0.8 2.4e-08 33.9 0.8 1.7 2 0 0 2 2 2 1 MIF4G domain Sec23_helical PF04815.15 VBB34836.1 - 0.12 12.2 0.4 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 helical domain LIM PF00412.22 VBB34838.1 - 1.1e-25 89.6 25.4 9.7e-14 51.3 10.4 2.1 2 0 0 2 2 2 2 LIM domain DUF627 PF04781.12 VBB34838.1 - 0.021 14.8 0.4 0.044 13.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Aminotran_1_2 PF00155.21 VBB34839.1 - 0.00034 19.9 0.0 0.00041 19.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nfu_N PF08712.11 VBB34840.1 - 0.046 13.8 0.2 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal FHIPEP PF00771.20 VBB34840.1 - 0.047 12.2 2.6 0.075 11.5 2.6 1.2 1 0 0 1 1 1 0 FHIPEP family An_peroxidase PF03098.15 VBB34841.1 - 3.1e-132 441.9 0.0 3.4e-132 441.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase RhoGAP PF00620.27 VBB34842.1 - 8.5e-43 145.8 0.0 1.2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF4357 PF14267.6 VBB34842.1 - 1.8 8.6 4.0 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) LBP_BPI_CETP_C PF02886.17 VBB34843.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain PPL5 PF18168.1 VBB34843.1 - 0.0041 16.5 1.5 0.0054 16.1 1.5 1.1 1 0 0 1 1 1 1 Prim-pol family 5 DNA_pol_B_thumb PF14791.6 VBB34843.1 - 0.075 13.2 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase beta thumb MscL PF01741.18 VBB34844.1 - 0.021 15.1 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Sarcoglycan_2 PF05510.13 VBB34844.1 - 0.042 12.6 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Tetraspanin PF00335.20 VBB34844.1 - 0.18 11.5 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family Baculo_VP91_N PF08475.10 VBB34844.1 - 0.35 10.5 1.9 0.72 9.5 0.0 2.1 2 1 0 2 2 2 0 Viral capsid protein 91 N-terminal Myosin_head PF00063.21 VBB34848.1 - 1.2e-81 275.0 0.2 1.4e-81 274.7 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 VBB34848.1 - 0.0012 18.6 0.2 0.0031 17.3 0.0 1.7 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 VBB34848.1 - 0.0043 17.5 0.0 0.0073 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 VBB34848.1 - 0.0047 17.2 0.0 0.0083 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 VBB34848.1 - 0.032 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 VBB34848.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 VBB34848.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.7 VBB34848.1 - 0.1 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain HisG_C PF08029.11 VBB34849.1 - 0.0024 18.0 0.0 0.0098 16.0 0.0 2.0 2 0 0 2 2 2 1 HisG, C-terminal domain An_peroxidase PF03098.15 VBB34850.1 - 8e-113 377.8 0.0 9.5e-113 377.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Tubulin_C PF03953.17 VBB34851.1 - 1.6e-50 170.5 0.0 2.5e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 VBB34851.1 - 7.1e-42 143.8 0.0 1e-41 143.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 VBB34851.1 - 0.0023 17.6 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MSP PF01716.18 VBB34851.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide ENTH PF01417.20 VBB34852.1 - 1.4e-46 157.6 0.0 2.1e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 VBB34852.1 - 3.5e-06 26.2 0.0 5.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Mito_fiss_reg PF05308.11 VBB34852.1 - 0.37 10.8 5.2 0.73 9.9 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator TMEM171 PF15471.6 VBB34852.1 - 3.7 6.5 6.5 5 6.0 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 An_peroxidase PF03098.15 VBB34853.1 - 5.8e-09 35.1 0.3 1.2e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 Animal haem peroxidase Ribos_L4_asso_C PF14374.6 VBB34853.1 - 0.2 11.7 1.0 3.5 7.7 0.3 2.6 2 1 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain PTB PF08416.13 VBB34854.1 - 2.2e-35 121.7 0.0 2.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain TAL_FSA PF00923.19 VBB34854.1 - 0.14 11.5 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Myosin_head PF00063.21 VBB34855.1 - 2.9e-49 167.9 0.2 4.8e-49 167.2 0.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 VBB34855.1 - 1.8e-21 76.7 0.5 3.6e-21 75.7 0.5 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Collagen PF01391.18 VBB34860.1 - 1.9e-12 46.8 78.4 2.5e-09 36.7 30.1 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF229 PF02995.17 VBB34861.1 - 5.1e-06 25.4 0.4 5.1e-06 25.4 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) RGS-like PF09128.11 VBB34862.1 - 1.8e-35 122.3 0.0 2.7e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RGS PF00615.19 VBB34862.1 - 2.4e-06 27.8 0.0 3.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain TPR_15 PF13429.6 VBB34862.1 - 0.028 13.6 0.1 0.056 12.7 0.1 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat L27_1 PF09058.10 VBB34862.1 - 0.086 12.8 0.3 13 5.8 0.0 2.4 2 1 0 2 2 2 0 L27_1 Ion_trans PF00520.31 VBB34864.1 - 0.00011 21.5 3.3 0.00014 21.2 3.3 1.1 1 0 0 1 1 1 1 Ion transport protein YhhN PF07947.14 VBB34864.1 - 0.017 14.8 1.2 0.021 14.5 1.2 1.1 1 0 0 1 1 1 0 YhhN family DUF3382 PF11862.8 VBB34864.1 - 0.022 15.0 0.3 0.032 14.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Herpes_LMP1 PF05297.11 VBB34864.1 - 0.091 12.0 1.0 0.11 11.7 1.0 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2207 PF09972.9 VBB34864.1 - 0.094 11.5 0.1 0.1 11.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EF-hand_1 PF00036.32 VBB34865.1 - 7.1e-29 97.2 10.0 8.3e-09 34.4 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 VBB34865.1 - 2.7e-23 82.2 1.5 8e-15 55.1 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB34865.1 - 3e-23 79.7 3.4 6.6e-09 35.0 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 VBB34865.1 - 1.6e-18 66.3 8.0 3.8e-13 49.1 0.2 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 VBB34865.1 - 1.4e-16 59.1 4.4 2.6e-06 26.6 0.1 3.4 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 VBB34865.1 - 9.3e-07 29.1 0.1 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 VBB34865.1 - 4.2e-05 23.4 0.3 0.00016 21.6 0.2 2.0 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 VBB34865.1 - 0.00054 20.3 0.0 0.004 17.5 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3016 PF11454.8 VBB34865.1 - 0.043 13.6 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) UPF0154 PF03672.13 VBB34865.1 - 0.044 13.8 2.9 0.13 12.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 VBB34865.1 - 0.045 13.7 0.3 4.6 7.1 0.0 2.7 1 1 2 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.18 VBB34865.1 - 0.083 13.1 0.1 1.7 8.9 0.0 2.5 1 1 1 2 2 2 0 Dockerin type I domain FGAR-AT_linker PF18072.1 VBB34865.1 - 0.099 13.2 0.2 0.28 11.7 0.1 1.8 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain UCH PF00443.29 VBB34866.1 - 0.0013 18.3 0.3 0.002 17.7 0.3 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADAM_CR_2 PF17771.1 VBB34867.1 - 8.4e-15 55.1 5.9 8.4e-15 55.1 5.9 2.8 2 1 1 3 3 3 1 ADAM cysteine-rich domain Reprolysin PF01421.19 VBB34867.1 - 9e-14 51.8 1.8 1.6e-13 51.0 1.8 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 VBB34867.1 - 7.2e-09 36.1 1.7 1.1e-08 35.5 1.7 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 VBB34867.1 - 2e-07 30.8 0.3 3.1e-07 30.2 0.3 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 VBB34867.1 - 1.4e-06 28.8 0.2 2.4e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 VBB34867.1 - 3.8e-06 26.9 0.6 6.8e-06 26.1 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 VBB34867.1 - 0.0076 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 VBB34867.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Patched PF02460.18 VBB34868.1 - 2.1e-08 32.8 0.1 2.5e-08 32.5 0.1 1.0 1 0 0 1 1 1 1 Patched family FeoB_Cyto PF17910.1 VBB34870.1 - 0.1 13.2 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 FeoB cytosolic helical domain DUF4784 PF16023.5 VBB34870.1 - 0.15 11.0 0.0 0.33 9.9 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4784) DUF236 PF03057.14 VBB34872.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 DUF236 repeat Patched PF02460.18 VBB34873.1 - 9.6e-39 133.1 6.0 1.2e-38 132.9 6.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 VBB34873.1 - 9e-18 64.6 4.5 1.6e-17 63.8 4.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Inhibitor_I29 PF08246.12 VBB34873.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) SLATT_2 PF18183.1 VBB34873.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 RSS_P20 PF11757.8 VBB34874.1 - 0.092 13.2 2.8 1.5 9.3 0.3 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Collagen PF01391.18 VBB34875.1 - 6.1e-19 67.5 72.4 1.1e-10 41.1 32.9 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) NOA36 PF06524.12 VBB34876.1 - 1.6 8.0 8.0 1.5 8.1 8.0 1.0 1 0 0 1 1 1 0 NOA36 protein Reprolysin PF01421.19 VBB34877.1 - 1.6e-09 37.9 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 VBB34877.1 - 2.1e-07 31.5 0.0 2.5e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 VBB34877.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 NOA36 PF06524.12 VBB34878.1 - 0.38 10.0 10.2 0.36 10.1 10.2 1.0 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 VBB34878.1 - 0.61 9.8 11.4 0.57 9.9 11.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 VBB34878.1 - 1 9.8 14.4 1.2 9.5 14.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 VBB34878.1 - 1.1 9.5 7.3 1.3 9.3 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 VBB34878.1 - 1.9 8.5 4.1 1.9 8.5 4.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 VBB34878.1 - 2.3 7.2 13.8 2.4 7.2 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 VBB34878.1 - 3.2 7.3 6.4 3.3 7.2 6.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 VBB34878.1 - 7.1 4.6 10.8 7.4 4.5 10.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 VBB34878.1 - 7.9 6.3 7.7 8.4 6.2 7.7 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region CH PF00307.31 VBB34880.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Calponin homology (CH) domain Collagen PF01391.18 VBB34881.1 - 6.2e-12 45.1 31.8 2.8e-10 39.8 31.8 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF4728 PF15860.5 VBB34883.1 - 2.7e-05 24.8 1.4 2.7e-05 24.8 1.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4728) DUF3796 PF12676.7 VBB34883.1 - 0.0056 17.1 4.3 0.0089 16.5 3.5 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3796) PIG-P PF08510.12 VBB34883.1 - 0.24 11.3 5.4 0.068 13.1 2.4 1.6 2 0 0 2 2 2 0 PIG-P Yip1 PF04893.17 VBB34883.1 - 0.37 10.5 9.7 0.98 9.1 0.5 2.1 1 1 1 2 2 2 0 Yip1 domain DUF2070 PF09843.9 VBB34883.1 - 1.2 7.4 6.5 1.4 7.1 6.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) S_4TM PF18159.1 VBB34883.1 - 1.6 7.9 5.9 0.25 10.6 1.5 1.7 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3830 PF12903.7 VBB34884.1 - 0.018 14.8 0.1 0.072 12.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) CRF PF00473.17 VBB34884.1 - 0.38 10.9 9.2 1.1 9.4 0.1 4.6 4 0 0 4 4 4 0 Corticotropin-releasing factor family FAD_binding_5 PF00941.21 VBB34884.1 - 0.66 9.7 7.0 15 5.3 0.0 3.7 3 1 0 3 3 3 0 FAD binding domain in molybdopterin dehydrogenase DUF1398 PF07166.11 VBB34884.1 - 0.95 9.5 6.8 7.2 6.7 0.2 4.6 1 1 3 5 5 5 0 Protein of unknown function (DUF1398) Tim54 PF11711.8 VBB34886.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF747 PF05346.11 VBB34888.1 - 0.11 12.0 1.3 0.14 11.6 1.3 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family AAA_25 PF13481.6 VBB34890.1 - 0.002 17.7 0.1 0.0033 17.0 0.1 1.3 1 1 0 1 1 1 1 AAA domain Glyco_transf_4 PF13439.6 VBB34890.1 - 0.048 13.7 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Rad51 PF08423.11 VBB34890.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Rad51 DUF1329 PF07044.11 VBB34890.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) Homeobox_KN PF05920.11 VBB34891.1 - 7.7e-08 32.1 0.4 1.5e-07 31.2 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain DEAD PF00270.29 VBB34893.1 - 1.7e-48 164.7 0.0 2.6e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 VBB34893.1 - 0.0039 17.2 0.0 0.017 15.1 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 VBB34893.1 - 0.004 16.5 0.0 0.004 16.5 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 VBB34893.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L6e PF01159.19 VBB34893.1 - 9.9 6.8 8.7 28 5.3 3.5 2.5 2 1 0 2 2 2 0 Ribosomal protein L6e Thioredoxin_6 PF13848.6 VBB34894.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain zf-C4H2 PF10146.9 VBB34895.1 - 2.2e-46 158.8 9.1 2.8e-46 158.5 9.1 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 VBB34895.1 - 0.0063 16.5 0.8 0.013 15.5 0.8 1.5 1 0 0 1 1 1 1 Double zinc ribbon Fez1 PF06818.15 VBB34895.1 - 0.013 16.0 1.7 0.018 15.5 1.7 1.4 1 0 0 1 1 1 0 Fez1 CortBP2 PF09727.9 VBB34895.1 - 0.013 15.4 4.1 0.023 14.6 4.1 1.4 1 0 0 1 1 1 0 Cortactin-binding protein-2 AKNA PF12443.8 VBB34895.1 - 0.069 13.8 0.5 0.17 12.5 0.5 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor zf-C4pol PF14260.6 VBB34895.1 - 0.41 11.2 8.8 0.94 10.0 2.9 3.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FapA PF03961.13 VBB34895.1 - 0.42 9.2 4.1 0.59 8.7 4.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMEM154 PF15102.6 VBB34896.1 - 0.022 14.7 0.8 0.042 13.8 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Ninjurin PF04923.12 VBB34896.1 - 0.074 13.0 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Ninjurin adh_short PF00106.25 VBB34898.1 - 1e-28 100.1 0.0 1.5e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB34898.1 - 5.2e-22 78.5 0.0 7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB34898.1 - 3.6e-05 23.7 0.0 5.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 VBB34898.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sigma70_ner PF04546.13 VBB34898.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ABC_tran PF00005.27 VBB34899.1 - 2.3e-07 31.4 0.5 5.2e-07 30.2 0.5 1.7 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 VBB34899.1 - 3.7e-05 23.7 0.1 5.2e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 VBB34899.1 - 0.00027 21.4 0.1 0.00036 21.0 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 VBB34899.1 - 0.00042 20.6 0.0 0.00054 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 VBB34899.1 - 0.00049 20.4 0.0 0.00066 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 VBB34899.1 - 0.00053 20.1 0.1 0.00083 19.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 VBB34899.1 - 0.0009 18.9 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 VBB34899.1 - 0.001 18.7 0.7 0.0021 17.7 0.4 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 VBB34899.1 - 0.0026 17.5 0.1 0.005 16.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 VBB34899.1 - 0.0029 18.2 0.0 0.0043 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 VBB34899.1 - 0.0036 17.2 0.1 0.0062 16.4 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 VBB34899.1 - 0.0047 17.0 0.1 0.0072 16.4 0.1 1.4 1 0 0 1 1 1 1 Dynamin family TsaE PF02367.17 VBB34899.1 - 0.0048 16.9 0.1 0.0071 16.4 0.1 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 VBB34899.1 - 0.0059 16.8 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 VBB34899.1 - 0.0097 15.0 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Septin PF00735.18 VBB34899.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 VBB34899.1 - 0.018 14.8 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 VBB34899.1 - 0.018 15.5 0.2 0.032 14.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 VBB34899.1 - 0.026 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_35 PF14516.6 VBB34899.1 - 0.028 13.3 0.1 0.034 13.0 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 VBB34899.1 - 0.029 14.1 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 VBB34899.1 - 0.031 13.6 0.4 0.13 11.5 0.3 1.9 1 1 1 2 2 2 0 Zeta toxin DUF815 PF05673.13 VBB34899.1 - 0.031 13.4 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 VBB34899.1 - 0.032 14.4 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 VBB34899.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA PF00004.29 VBB34899.1 - 0.053 13.9 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 VBB34899.1 - 0.058 12.6 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DnaB_C PF03796.15 VBB34899.1 - 0.063 12.6 0.2 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 VBB34899.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 VBB34899.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 VBB34899.1 - 0.08 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase NTPase_1 PF03266.15 VBB34899.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.18 VBB34899.1 - 0.089 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.6 VBB34899.1 - 0.094 12.5 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 VBB34899.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 VBB34899.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain BACK PF07707.15 VBB34900.1 - 0.0069 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ion_trans_2 PF07885.16 VBB34901.1 - 1.4e-17 63.4 0.7 1.4e-17 63.4 0.7 2.5 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 VBB34901.1 - 2.2e-05 23.8 2.4 2.2e-05 23.8 2.4 2.5 2 2 0 2 2 2 1 Ion transport protein Orf78 PF06024.12 VBB34901.1 - 0.036 14.3 1.5 0.1 12.9 0.8 2.1 2 0 0 2 2 2 0 Orf78 (ac78) LRRC37AB_C PF14914.6 VBB34901.1 - 0.19 11.6 1.1 15 5.5 0.2 2.4 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Peroxin-13_N PF04088.13 VBB34901.1 - 0.22 11.8 1.9 0.31 11.3 0.1 2.1 3 0 0 3 3 3 0 Peroxin 13, N-terminal region AMP-binding PF00501.28 VBB34902.1 - 2.7e-73 247.0 0.0 3.5e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB34902.1 - 1.5e-05 25.9 0.0 3.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-H2C2_2 PF13465.6 VBB34905.1 - 1.2e-13 50.8 12.1 5.4e-08 32.9 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB34905.1 - 3e-05 24.2 18.8 0.0096 16.3 2.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB34905.1 - 3e-05 24.5 16.3 0.0019 18.9 1.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 VBB34905.1 - 0.0092 16.4 8.0 0.097 13.1 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type C1_2 PF03107.16 VBB34905.1 - 0.013 15.7 5.7 0.51 10.7 1.5 2.5 1 1 1 2 2 2 0 C1 domain zf-C2H2_jaz PF12171.8 VBB34905.1 - 0.017 15.4 4.7 0.059 13.7 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 VBB34905.1 - 2.6 8.1 15.5 0.71 9.9 1.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Astacin PF01400.24 VBB34906.1 - 1.8e-15 57.1 0.0 2.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) NRho PF16733.5 VBB34906.1 - 0.2 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Rhomboid N-terminal domain Collagen PF01391.18 VBB34907.1 - 1.4e-08 34.3 42.6 7.7e-07 28.8 42.6 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ribosomal_L24e PF01246.20 VBB34908.1 - 3.1e-07 30.5 0.1 9.9e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e 3Beta_HSD PF01073.19 VBB34909.1 - 7.3e-42 143.3 0.0 8.1e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 VBB34909.1 - 1.2e-24 87.1 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 VBB34909.1 - 7.8e-12 45.2 0.0 8.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 VBB34909.1 - 2.3e-11 44.0 0.0 5.1e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 VBB34909.1 - 1.9e-09 37.1 0.0 2.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 VBB34909.1 - 2.1e-08 33.6 0.1 7.3e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 VBB34909.1 - 1.2e-05 24.6 0.2 2.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 VBB34909.1 - 2.3e-05 24.1 0.0 4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 VBB34909.1 - 0.00088 19.5 0.0 0.0024 18.1 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 VBB34909.1 - 0.0026 17.3 0.4 0.064 12.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 VBB34909.1 - 0.016 15.1 0.4 0.93 9.4 0.1 2.2 1 1 0 2 2 2 0 KR domain Ferritin PF00210.24 VBB34910.1 - 0.22 11.5 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain DUF3377 PF11857.8 VBB34913.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Laminin_G_2 PF02210.24 VBB34914.1 - 5.6e-27 94.8 0.0 7.5e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 VBB34914.1 - 3.8e-23 82.1 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain EGF_2 PF07974.13 VBB34914.1 - 0.025 14.9 9.4 0.041 14.2 9.4 1.4 1 0 0 1 1 1 0 EGF-like domain Plasmod_Pvs28 PF06247.11 VBB34914.1 - 0.092 13.1 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Pvs28 EGF domain Laminin_EGF PF00053.24 VBB34914.1 - 0.14 12.3 5.3 0.29 11.3 5.3 1.5 1 0 0 1 1 1 0 Laminin EGF domain Pkinase PF00069.25 VBB34916.1 - 0.029 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Cation_ATPase PF13246.6 VBB34919.1 - 1.3e-21 76.4 0.0 1.3e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 VBB34919.1 - 2e-11 44.6 0.0 1.2e-10 42.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 VBB34919.1 - 2e-06 27.4 0.4 2.9e-06 26.9 0.4 1.3 1 0 0 1 1 1 1 E1-E2 ATPase AMP-binding PF00501.28 VBB34920.1 - 7.4e-73 245.5 0.0 9.8e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB34920.1 - 1.4e-05 25.9 0.0 3.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7tm_2 PF00002.24 VBB34921.1 - 1.8e-52 178.1 8.8 2e-52 177.9 8.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPI2 PF06432.11 VBB34921.1 - 1.7 8.0 7.4 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase HU-CCDC81_bac_2 PF18175.1 VBB34922.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Collagen PF01391.18 VBB34923.1 - 5.4e-15 54.9 70.4 1.8e-09 37.2 28.6 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Vps54 PF07928.12 VBB34924.1 - 0.044 14.2 1.0 0.044 14.2 1.0 2.9 2 1 1 3 3 3 0 Vps54-like protein KID PF02524.14 VBB34924.1 - 0.19 11.9 2.0 0.53 10.6 0.1 2.9 2 0 0 2 2 2 0 KID repeat APG17 PF04108.12 VBB34924.1 - 0.26 10.3 31.8 0.24 10.5 9.8 3.0 2 1 0 2 2 2 0 Autophagy protein Apg17 PilJ PF13675.6 VBB34924.1 - 0.54 10.3 8.6 14 5.7 0.2 3.5 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc7 PF08317.11 VBB34924.1 - 0.58 9.0 47.6 0.32 9.8 14.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 VBB34924.1 - 2.3 7.2 34.8 1.3 8.0 18.7 2.1 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4349 PF14257.6 VBB34924.1 - 3.7 6.9 15.3 0.28 10.6 4.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF489 PF04356.12 VBB34924.1 - 6.5 6.7 15.8 0.066 13.2 1.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF489) Metallophos PF00149.28 VBB34925.1 - 2.2e-19 70.8 0.0 2e-16 61.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 VBB34925.1 - 2.9e-07 30.8 0.1 4.5e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BDHCT_assoc PF16204.5 VBB34926.1 - 0.3 10.7 2.1 0.31 10.7 2.1 1.0 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Ldl_recept_a PF00057.18 VBB34927.1 - 8.8e-41 137.8 95.7 8e-12 45.2 9.2 7.7 6 2 0 6 6 6 5 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 VBB34927.1 - 2.2e-12 47.2 3.1 4.2e-07 30.3 0.1 3.5 3 0 0 3 3 3 2 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 VBB34927.1 - 8.7e-08 32.3 20.0 2.9e-07 30.7 9.1 5.0 3 2 1 4 4 4 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB34927.1 - 3.4e-05 23.7 0.3 3.4e-05 23.7 0.3 4.7 4 0 0 4 4 4 1 Complement Clr-like EGF-like EGF_CA PF07645.15 VBB34927.1 - 0.02 15.1 9.4 0.02 15.1 9.4 7.5 3 2 2 5 5 5 0 Calcium-binding EGF domain SGL PF08450.12 VBB34927.1 - 0.025 14.1 2.3 0.39 10.2 0.1 3.0 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region UQ_con PF00179.26 VBB34928.1 - 1.1e-30 106.2 0.2 1.3e-30 105.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 VBB34928.1 - 2.6e-05 23.9 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 VBB34928.1 - 0.055 13.8 0.4 0.065 13.5 0.4 1.4 1 1 0 1 1 1 0 RWD domain WD40 PF00400.32 VBB34930.1 - 7.9e-23 80.3 11.9 5.9e-06 26.9 0.3 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat WGG PF10273.9 VBB34930.1 - 7.8e-16 58.5 0.6 2.2e-15 57.0 0.4 1.9 1 1 1 2 2 2 1 Pre-rRNA-processing protein TSR2 ANAPC4_WD40 PF12894.7 VBB34930.1 - 2.7e-06 27.6 0.1 0.14 12.5 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 VBB34930.1 - 0.003 17.5 0.0 1.3 8.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRP7 PF12923.7 VBB34930.1 - 0.015 15.4 0.2 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PD40 PF07676.12 VBB34930.1 - 0.034 14.1 0.1 5.6 7.0 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat UPF0561 PF10573.9 VBB34931.1 - 1.8 8.7 9.9 1.2 9.2 2.2 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 GIT_CC PF16559.5 VBB34933.1 - 0.0047 16.8 5.4 0.0047 16.8 5.4 5.5 4 1 1 5 5 5 1 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 VBB34933.1 - 0.0058 17.0 0.7 0.0058 17.0 0.7 6.7 6 1 1 7 7 7 3 Cell division protein ZapB PSI PF01437.25 VBB34938.1 - 9.3e-07 29.3 2.6 9.3e-07 29.3 2.6 2.1 3 0 0 3 3 3 1 Plexin repeat PSI_integrin PF17205.3 VBB34938.1 - 0.06 13.1 2.7 0.14 12.0 2.7 1.7 1 0 0 1 1 1 0 Integrin plexin domain Claudin_2 PF13903.6 VBB34938.1 - 0.063 13.0 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CLIP_SPH_Scar PF18399.1 VBB34938.1 - 0.068 13.3 0.2 0.068 13.3 0.2 1.7 2 0 0 2 2 2 0 Clip-domain serine protease homolog Scarface DUF4064 PF13273.6 VBB34938.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Collagen PF01391.18 VBB34939.1 - 2.3e-10 40.0 42.8 9.7e-09 34.9 42.8 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) EGF PF00008.27 VBB34940.1 - 5.6e-38 128.8 110.5 4.6e-07 30.0 5.8 9.0 9 0 0 9 9 9 8 EGF-like domain hEGF PF12661.7 VBB34940.1 - 6.1e-22 77.4 99.3 0.00037 21.0 3.0 10.5 10 0 0 10 10 10 8 Human growth factor-like EGF EGF_3 PF12947.7 VBB34940.1 - 3.6e-11 43.0 97.5 0.0038 17.4 2.6 9.0 8 1 1 9 9 9 8 EGF domain EGF_2 PF07974.13 VBB34940.1 - 5.2e-05 23.5 118.2 0.023 15.1 7.6 9.3 8 1 0 8 8 8 6 EGF-like domain EGF_MSP1_1 PF12946.7 VBB34940.1 - 0.0052 16.8 1.6 0.0052 16.8 1.6 8.5 9 0 0 9 9 9 2 MSP1 EGF domain 1 EGF_CA PF07645.15 VBB34940.1 - 0.021 15.0 111.5 0.043 14.0 6.8 9.6 3 2 6 9 9 9 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 VBB34940.1 - 0.1 12.9 93.1 0.17 12.2 3.6 9.0 4 2 3 7 7 7 0 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 VBB34940.1 - 0.32 11.1 95.3 2.9 8.1 5.9 8.6 1 1 7 8 8 8 0 Laminin EGF domain Annexin PF00191.20 VBB34942.1 - 1.3e-56 188.5 2.9 2.1e-22 79.0 0.0 3.1 3 0 0 3 3 3 3 Annexin YlbE PF14003.6 VBB34942.1 - 0.0061 17.0 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 1 YlbE-like protein FeoB_Cyto PF17910.1 VBB34942.1 - 0.064 13.8 0.4 2.2 8.9 0.0 2.9 2 1 0 3 3 3 0 FeoB cytosolic helical domain TFIID-31kDa PF02291.15 VBB34944.1 - 0.13 12.3 0.1 0.37 10.9 0.1 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit UPF0561 PF10573.9 VBB34944.1 - 1.2 9.3 9.1 1.3 9.1 2.3 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF4592 PF15262.6 VBB34944.1 - 4.2 8.1 12.4 1.4 9.6 8.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4592) PPDFL PF15060.6 VBB34945.1 - 0.036 14.6 2.7 0.043 14.4 2.7 1.1 1 0 0 1 1 1 0 Differentiation and proliferation regulator p450 PF00067.22 VBB34946.1 - 6.5e-78 262.5 0.0 7.6e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF393 PF04134.12 VBB34946.1 - 0.0052 18.1 0.9 0.16 13.3 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function, DUF393 DUF402 PF04167.13 VBB34946.1 - 0.019 15.1 0.6 0.06 13.5 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF402) DUF5641 PF18701.1 VBB34947.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5641) tRNA_synt_1c_R1 PF04558.15 VBB34947.1 - 0.0092 16.0 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 C2 PF00168.30 VBB34948.1 - 3.2e-16 59.5 0.0 1e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain C1_1 PF00130.22 VBB34948.1 - 3.6e-14 52.4 4.7 5.9e-14 51.7 4.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 VBB34948.1 - 0.056 13.8 1.1 0.098 13.0 1.1 1.4 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 VBB34948.1 - 0.066 13.5 3.6 0.22 11.9 3.6 2.0 1 1 0 1 1 1 0 RING-like domain Opi1 PF08618.10 VBB34948.1 - 0.085 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 DUF3967 PF13152.6 VBB34948.1 - 0.089 12.6 0.8 0.45 10.3 0.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3967) PHD_2 PF13831.6 VBB34948.1 - 0.11 12.1 0.8 0.11 12.1 0.8 1.8 2 0 0 2 2 2 0 PHD-finger Collagen PF01391.18 VBB34951.1 - 1.5e-08 34.2 17.8 1.8e-08 34.0 17.8 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) LPAM_2 PF13627.6 VBB34951.1 - 0.089 12.7 0.6 0.089 12.7 0.6 1.6 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site 7tm_1 PF00001.21 VBB34952.1 - 7.1e-38 130.4 9.1 7.9e-38 130.3 9.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB34952.1 - 1.1e-06 28.2 7.4 2.1e-06 27.3 7.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 VBB34952.1 - 0.00071 19.4 2.8 0.001 18.8 2.8 1.3 1 0 0 1 1 1 1 Olfactory receptor DUF2116 PF09889.9 VBB34952.1 - 0.083 12.9 0.4 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) 7TM_GPCR_Srx PF10328.9 VBB34952.1 - 2.2 7.8 15.0 2 8.0 13.7 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx MadM PF03818.13 VBB34952.1 - 3 7.8 11.4 1.7 8.5 0.1 3.6 4 1 1 5 5 5 0 Malonate/sodium symporter MadM subunit Mucin PF01456.17 VBB34953.1 - 0.44 10.5 39.0 0.56 10.2 39.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein NUDE_C PF04880.13 VBB34953.1 - 1.6 9.2 8.1 1.8 9.0 8.1 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DNA_pol_phi PF04931.13 VBB34954.1 - 2.3 6.2 11.4 2.2 6.3 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 VBB34954.1 - 6.8 5.9 17.8 8.1 5.7 17.8 1.1 1 0 0 1 1 1 0 NOA36 protein Collagen PF01391.18 VBB34955.1 - 2.1e-18 65.8 80.6 1.5e-05 24.7 34.2 4.5 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Endostatin PF06482.11 VBB34955.1 - 4.1e-05 23.2 0.0 5.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF4576 PF15144.6 VBB34956.1 - 6.6 6.7 0.0 6.6 6.7 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4576) Spec3 PF15795.5 VBB34957.1 - 3.5e-05 24.2 1.8 6e-05 23.5 1.8 1.4 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein F5_F8_type_C PF00754.25 VBB34958.1 - 2.8e-17 63.0 0.0 4.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Astacin PF01400.24 VBB34959.1 - 4e-34 117.9 0.1 5.6e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 VBB34959.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 VBB34959.1 - 0.027 14.3 3.8 0.16 11.8 0.6 2.6 2 1 1 3 3 3 0 Matrixin Peptidase_M66 PF10462.9 VBB34959.1 - 0.031 13.2 2.3 0.048 12.6 2.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 VBB34959.1 - 0.05 14.1 0.1 0.095 13.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Acyl-CoA_dh_M PF02770.19 VBB34962.1 - 0.0032 17.6 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pkinase_Tyr PF07714.17 VBB34963.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 VBB34963.1 - 0.0049 16.3 0.0 0.0098 15.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain FA_desaturase PF00487.24 VBB34964.1 - 8.4e-25 88.1 5.9 2.3e-20 73.5 2.6 2.1 1 1 1 2 2 2 2 Fatty acid desaturase RVT_1 PF00078.27 VBB34965.1 - 0.0038 16.8 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-ph_phosp PF04029.14 VBB34965.1 - 0.11 11.6 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase PAN_1 PF00024.26 VBB34968.1 - 7.3e-07 29.1 9.6 5.7e-06 26.2 3.6 2.3 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 VBB34968.1 - 1.9e-06 27.7 12.7 2e-05 24.4 5.3 2.6 2 1 0 2 2 2 2 PAN domain PAN_2 PF08276.11 VBB34968.1 - 5.9 7.1 13.0 0.97 9.6 5.4 2.4 2 1 0 2 2 2 0 PAN-like domain hGDE_N PF14699.6 VBB34969.1 - 0.0044 17.1 0.8 0.0076 16.4 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Metallophos PF00149.28 VBB34970.1 - 2.8e-23 83.5 0.3 9.1e-23 81.8 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AHJR-like PF18743.1 VBB34970.1 - 0.092 12.3 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 0 REase_AHJR-like DUF2427 PF10348.9 VBB34970.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Glyco_hydro_38C PF07748.13 VBB34971.1 - 2.8e-09 37.4 0.3 9.3e-08 32.4 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain PhoLip_ATPase_C PF16212.5 VBB34972.1 - 2.1e-39 135.8 21.7 3.8e-31 108.7 5.2 2.0 1 1 1 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 VBB34972.1 - 0.0017 18.1 0.1 0.0026 17.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FmrO PF07091.11 VBB34972.1 - 0.077 12.5 1.1 0.11 12.0 1.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Hydrolase PF00702.26 VBB34972.1 - 0.093 13.0 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase malic PF00390.19 VBB34973.1 - 1.6e-12 47.6 0.0 4.6e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Aconitase PF00330.20 VBB34974.1 - 1.9e-89 300.8 0.0 2.2e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF3579 PF12112.8 VBB34975.1 - 0.052 14.1 0.0 0.053 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) TBD PF12845.7 VBB34975.1 - 0.1 12.5 0.3 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 TBD domain DUF5641 PF18701.1 VBB34979.1 - 1e-14 54.4 0.2 2.4e-14 53.2 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 VBB34979.1 - 0.00014 21.9 1.1 0.0003 20.8 1.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 VBB34979.1 - 0.0045 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-UBR PF02207.20 VBB34983.1 - 0.044 14.0 0.9 0.065 13.4 0.9 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-H2C2_2 PF13465.6 VBB34983.1 - 0.11 12.9 1.8 7.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Patched PF02460.18 VBB34986.1 - 6.3e-15 54.3 2.6 7.5e-15 54.1 2.6 1.0 1 0 0 1 1 1 1 Patched family Inhibitor_I29 PF08246.12 VBB34986.1 - 0.061 13.8 0.0 0.061 13.8 0.0 1.1 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) zf-LITAF-like PF10601.9 VBB34987.1 - 5.7e-07 29.7 1.7 7.8e-07 29.3 1.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain TMEM215 PF15746.5 VBB34987.1 - 0.034 13.6 0.4 0.051 13.0 0.4 1.2 1 0 0 1 1 1 0 TMEM215 family Ion_trans_2 PF07885.16 VBB34988.1 - 1.1e-31 108.6 14.4 5.4e-17 61.5 2.6 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 VBB34988.1 - 2.1e-05 23.9 11.4 0.0065 15.7 4.7 2.2 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 VBB34988.1 - 0.055 13.3 3.4 1.4 8.7 0.1 2.6 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Pou PF00157.17 VBB34990.1 - 1.3e-29 102.0 0.0 2.9e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain HTH_31 PF13560.6 VBB34990.1 - 0.0063 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain CBP_BcsO PF17037.5 VBB34990.1 - 0.034 14.3 6.2 0.052 13.7 6.2 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Adeno_PV PF03910.13 VBB34990.1 - 0.38 9.4 2.0 0.39 9.4 0.4 1.7 2 0 0 2 2 2 0 Adenovirus minor core protein PV Peptidase_A17 PF05380.13 VBB34993.1 - 1e-15 58.1 0.0 1.6e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase Glycoprotein_B PF00606.18 VBB34993.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain TSP_1 PF00090.19 VBB34994.1 - 1.1e-06 28.7 28.1 0.0017 18.6 8.6 3.5 3 1 0 3 3 3 2 Thrombospondin type 1 domain zf-C3HC4 PF00097.25 VBB34995.1 - 2.5e-05 24.0 4.9 5.3e-05 23.0 4.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 VBB34995.1 - 0.0025 17.7 6.1 0.0041 17.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 VBB34995.1 - 0.0036 17.4 3.5 0.0069 16.5 3.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 VBB34995.1 - 0.0073 16.3 1.1 0.0087 16.0 1.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 VBB34995.1 - 0.018 14.9 9.6 0.049 13.5 9.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 VBB34995.1 - 0.041 14.2 7.5 0.073 13.4 7.5 1.5 1 0 0 1 1 1 0 Ring finger domain HSP20 PF00011.21 VBB34997.1 - 3.3e-21 75.3 0.7 4.2e-21 75.0 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 VBB34998.1 - 3.3e-21 75.3 0.7 4.2e-21 75.0 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DSPc PF00782.20 VBB34999.1 - 0.027 14.3 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Sm_like PF16243.5 VBB34999.1 - 0.1 12.7 0.3 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Sm_like domain NTP_transf_2 PF01909.23 VBB34999.1 - 0.16 12.3 0.3 2.9 8.3 0.1 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain Na_Ca_ex PF01699.24 VBB35000.1 - 3.5e-20 72.5 9.2 3.5e-20 72.5 9.2 1.5 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Rav1p_C PF12234.8 VBB35001.1 - 0.0012 17.3 1.3 0.57 8.5 0.0 2.1 1 1 1 2 2 2 2 RAVE protein 1 C terminal Bacillus_HBL PF05791.11 VBB35001.1 - 0.0019 18.0 6.7 0.002 18.0 3.5 2.4 2 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) BAR_3 PF16746.5 VBB35001.1 - 0.0021 17.8 6.4 0.0026 17.5 5.5 1.6 1 1 0 1 1 1 1 BAR domain of APPL family OmpH PF03938.14 VBB35001.1 - 0.0053 17.1 0.9 0.0053 17.1 0.9 2.7 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) DUF948 PF06103.11 VBB35001.1 - 0.02 15.2 1.3 0.44 10.8 0.1 3.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 VBB35001.1 - 0.03 14.3 3.6 1.2 9.2 1.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF668 PF05003.12 VBB35001.1 - 0.084 13.4 0.9 0.3 11.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF668) DUF4407 PF14362.6 VBB35001.1 - 0.086 12.2 2.8 0.2 11.0 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MDD_C PF18376.1 VBB35001.1 - 0.1 12.3 0.3 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain DUF4047 PF13256.6 VBB35001.1 - 0.24 11.6 4.1 0.14 12.4 0.7 2.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4047) DUF87 PF01935.17 VBB35001.1 - 0.27 11.3 4.1 0.63 10.1 4.0 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain DUF883 PF05957.13 VBB35001.1 - 0.29 11.8 2.8 5.4 7.7 0.0 2.8 2 1 0 3 3 2 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.14 VBB35001.1 - 0.63 9.8 5.9 0.21 11.4 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PdaC PF13739.6 VBB35001.1 - 0.96 10.5 6.6 4.8e+02 1.8 6.6 3.3 1 1 0 1 1 1 0 Deacetylase PdaC DUF4154 PF13689.6 VBB35002.1 - 0.083 13.1 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 YfiR/HmsC-like MEDS PF14417.6 VBB35002.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain rve PF00665.26 VBB35005.1 - 1.2e-05 25.5 0.0 2.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain HdeA PF06411.11 VBB35005.1 - 0.049 13.8 0.2 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 HdeA/HdeB family DUF5440 PF17509.2 VBB35005.1 - 0.061 12.9 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5440) CAP PF00188.26 VBB35007.1 - 1.1e-22 81.2 6.4 1.4e-22 80.9 6.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Na_Ca_ex_C PF16494.5 VBB35007.1 - 0.044 14.2 0.0 0.061 13.8 0.0 1.2 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Myticin-prepro PF10690.9 VBB35007.1 - 0.28 11.4 3.2 0.61 10.4 3.2 1.5 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Motile_Sperm PF00635.26 VBB35008.1 - 8.3e-05 22.4 0.1 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PhageMin_Tail PF10145.9 VBB35008.1 - 0.031 14.1 0.6 0.043 13.7 0.6 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein E2F_TDP PF02319.20 VBB35009.1 - 3.2e-07 30.3 0.0 8.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain PDZ PF00595.24 VBB35010.1 - 7.3e-09 35.9 0.0 8.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB35010.1 - 8.5e-05 22.3 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 PDZ domain DUF760 PF05542.11 VBB35011.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF760) Neur_chan_memb PF02932.16 VBB35012.1 - 3.4e-25 89.5 0.0 4e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Sigma70_ner PF04546.13 VBB35013.1 - 7.2 6.4 29.2 7.3 6.4 29.2 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region MtN3_slv PF03083.16 VBB35014.1 - 0.056 13.5 2.0 0.077 13.0 2.0 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange EVC2_like PF12297.8 VBB35014.1 - 0.1 11.3 0.8 0.13 10.9 0.8 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Beta-lactamase PF00144.24 VBB35015.1 - 7.7e-47 160.1 0.0 9.6e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase zf-C2HC PF01530.18 VBB35016.1 - 8.4e-13 48.3 10.6 1.7e-12 47.3 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C2HC type GRP PF07172.11 VBB35018.1 - 0.04 14.6 14.5 0.23 12.2 7.5 2.7 2 1 1 3 3 3 0 Glycine rich protein family Hormone_recep PF00104.30 VBB35019.1 - 4.3e-07 29.7 1.6 5e-07 29.5 1.6 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Telomere_reg-2 PF10193.9 VBB35019.1 - 0.059 13.8 0.2 0.078 13.4 0.2 1.3 1 0 0 1 1 1 0 Telomere length regulation protein Collagen PF01391.18 VBB35020.1 - 6.1e-11 41.9 36.2 1.1e-10 41.1 36.2 1.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) JAKMIP_CC3 PF16034.5 VBB35021.1 - 1.1e-05 25.4 18.5 1.1e-05 25.4 18.5 2.0 1 1 1 2 2 2 1 JAKMIP CC3 domain DUF1758 PF05585.12 VBB35022.1 - 7.4e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) DUF1759 PF03564.15 VBB35022.1 - 0.039 13.9 0.3 1.6 8.6 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) DUF3899 PF13038.6 VBB35022.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Pkinase PF00069.25 VBB35023.1 - 1.7e-10 40.7 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35023.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ets PF00178.22 VBB35025.1 - 2e-35 121.1 1.4 3.2e-35 120.5 1.4 1.3 1 0 0 1 1 1 1 Ets-domain DUF2400 PF09674.10 VBB35026.1 - 0.021 14.8 0.5 1.2 9.1 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2400) EDR1 PF14381.6 VBB35026.1 - 0.032 13.9 0.4 0.05 13.3 0.4 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Herpes_UL3 PF03369.13 VBB35026.1 - 0.15 12.6 0.7 0.25 11.9 0.3 1.6 2 0 0 2 2 2 0 Herpesvirus UL3 protein ANAPC15 PF15243.6 VBB35026.1 - 9.1 6.8 7.5 0.5 10.8 1.9 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 SNF PF00209.18 VBB35028.1 - 1.8e-40 139.2 9.3 2e-40 139.0 9.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3938 PF13074.6 VBB35028.1 - 0.14 12.4 2.4 0.26 11.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Tmemb_18A PF09771.9 VBB35028.1 - 0.16 12.4 0.2 0.31 11.5 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Herpes_LMP1 PF05297.11 VBB35028.1 - 0.36 10.0 4.6 0.44 9.7 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) GSHPx PF00255.19 VBB35029.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase Peptidase_A17 PF05380.13 VBB35029.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Pao retrotransposon peptidase cwf21 PF08312.12 VBB35030.1 - 0.00022 21.3 1.8 0.00025 21.1 0.7 1.6 2 0 0 2 2 2 1 cwf21 domain Forkhead PF00250.18 VBB35031.1 - 2.6e-07 30.8 0.0 5.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Tir_receptor_C PF07489.11 VBB35031.1 - 1.2 9.0 13.5 1.6 8.6 13.5 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus GPCR_chapero_1 PF11904.8 VBB35032.1 - 7.8e-64 216.0 0.1 9e-64 215.8 0.1 1.0 1 0 0 1 1 1 1 GPCR-chaperone ShK PF01549.24 VBB35034.1 - 1.7e-05 25.3 6.2 2.7e-05 24.6 6.2 1.4 1 0 0 1 1 1 1 ShK domain-like Collagen PF01391.18 VBB35035.1 - 8.3e-15 54.3 67.9 1.5e-08 34.3 30.9 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) JAKMIP_CC3 PF16034.5 VBB35036.1 - 2.4e-05 24.4 19.2 2.4e-05 24.4 19.2 2.2 1 1 1 2 2 2 1 JAKMIP CC3 domain PALP PF00291.25 VBB35037.1 - 2.4e-34 119.1 0.0 2.6e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NUDIX_2 PF13869.6 VBB35039.1 - 2.2e-56 190.4 0.1 2.7e-56 190.1 0.1 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase SMC_hinge PF06470.13 VBB35041.1 - 0.007 16.7 0.0 0.0084 16.4 0.0 1.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Annexin PF00191.20 VBB35042.1 - 1.8e-20 72.8 9.9 8.3e-11 41.8 0.2 3.8 3 1 1 4 4 4 3 Annexin GGA_N-GAT PF18308.1 VBB35042.1 - 0.0054 16.3 0.1 0.015 14.9 0.1 1.8 1 0 0 1 1 1 1 GGA N-GAT domain DUF4259 PF14078.6 VBB35042.1 - 0.2 12.4 0.7 1.7 9.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4259) FliL PF03748.14 VBB35042.1 - 1.3 9.6 7.4 28 5.4 5.8 2.9 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL BTB_2 PF02214.22 VBB35043.1 - 1.3e-29 102.3 0.0 1.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 VBB35043.1 - 0.049 13.7 0.0 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 BTB/POZ domain Collagen PF01391.18 VBB35047.1 - 6.1e-11 41.9 36.2 1.1e-10 41.1 36.2 1.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) START PF01852.19 VBB35048.1 - 1.2e-20 73.8 0.0 1.6e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 START domain Ldl_recept_a PF00057.18 VBB35049.1 - 3.3e-09 36.8 12.5 3.3e-09 36.8 12.5 1.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A I-set PF07679.16 VBB35049.1 - 5.4e-07 29.6 0.0 1e-06 28.7 0.0 1.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB35049.1 - 2.6e-05 24.7 0.0 5.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Flagellin_D3 PF08884.11 VBB35049.1 - 0.014 15.8 0.3 0.018 15.4 0.3 1.2 1 0 0 1 1 1 0 Flagellin D3 domain ubiquitin PF00240.23 VBB35049.1 - 0.044 13.5 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family zf-UBR PF02207.20 VBB35050.1 - 0.00011 22.2 5.8 0.00023 21.3 5.8 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Collagen PF01391.18 VBB35051.1 - 5.6e-26 90.1 108.4 4.8e-10 39.0 38.6 4.2 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) DERM PF14704.6 VBB35052.1 - 0.0017 18.8 2.3 0.0026 18.2 2.3 1.2 1 0 0 1 1 1 1 Dermatopontin zf-C4 PF00105.18 VBB35053.1 - 3.6e-16 59.4 0.2 4.2e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) VWA PF00092.28 VBB35054.1 - 6.5e-11 42.8 0.1 1.1e-10 42.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Zona_pellucida PF00100.23 VBB35054.1 - 1.9e-09 37.7 1.2 2.2e-09 37.5 1.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Parvo_coat_N PF08398.10 VBB35054.1 - 0.17 12.0 0.1 25 5.1 0.0 2.4 2 0 0 2 2 2 0 Parvovirus coat protein VP1 Zona_pellucida PF00100.23 VBB35057.1 - 4.9e-07 29.8 0.8 6.4e-07 29.4 0.8 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Nuc_sug_transp PF04142.15 VBB35058.1 - 2.5e-09 36.8 0.0 2.6e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter Patched PF02460.18 VBB35059.1 - 6.9e-07 27.7 0.0 8e-07 27.5 0.0 1.0 1 0 0 1 1 1 1 Patched family RVT_1 PF00078.27 VBB35060.1 - 1.1e-36 126.4 0.0 6.5e-36 123.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 VBB35060.1 - 7.4e-09 35.5 0.3 4e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 VBB35060.1 - 8.5e-06 25.5 0.0 2.8e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family E1-E2_ATPase PF00122.20 VBB35061.1 - 1.9e-45 154.6 4.9 9.7e-33 113.2 0.9 2.1 1 1 1 2 2 2 2 E1-E2 ATPase NLPC_P60 PF00877.19 VBB35061.1 - 0.018 15.1 0.0 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 NlpC/P60 family Hydrolase PF00702.26 VBB35061.1 - 0.028 14.7 0.8 0.075 13.3 0.2 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Collagen PF01391.18 VBB35062.1 - 5.1e-27 93.4 103.2 2.5e-10 39.9 37.8 3.6 2 1 0 3 3 3 3 Collagen triple helix repeat (20 copies) Ig_3 PF13927.6 VBB35065.1 - 6.1e-15 55.6 0.0 9.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 VBB35065.1 - 9.2e-14 51.5 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 VBB35065.1 - 9.8e-14 51.2 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 VBB35065.1 - 9.1e-12 45.0 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 VBB35065.1 - 2.3e-10 40.6 0.1 4.2e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 VBB35065.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 VBB35065.1 - 0.0013 19.1 0.0 0.0035 17.7 0.0 1.6 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 VBB35065.1 - 0.0025 17.9 0.0 0.0038 17.3 0.0 1.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 VBB35065.1 - 0.0029 17.8 0.0 0.0034 17.6 0.0 1.1 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Ig_4 PF16680.5 VBB35065.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 VBB35065.1 - 0.044 13.8 0.2 0.056 13.4 0.2 1.4 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 VBB35065.1 - 0.05 13.6 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 C17orf99 Ig domain Izumo-Ig PF16706.5 VBB35065.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 VBB35065.1 - 0.078 13.4 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Kunitz_BPTI PF00014.23 VBB35066.1 - 1.5e-34 118.0 24.4 9e-18 64.3 6.9 3.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Metallophos PF00149.28 VBB35067.1 - 1.5e-18 68.0 0.3 1.8e-18 67.8 0.3 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PolyG_pol PF01518.16 VBB35067.1 - 0.057 12.1 0.0 0.21 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma NS protein Metallophos_2 PF12850.7 VBB35067.1 - 0.13 12.5 0.0 1.3 9.2 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L40e PF01020.17 VBB35068.1 - 1.8e-31 107.8 11.4 2.6e-31 107.2 11.4 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 VBB35068.1 - 2.6e-08 33.5 0.5 4.5e-08 32.7 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 VBB35068.1 - 0.039 13.8 0.1 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Fer2_3 PF13085.6 VBB35068.1 - 0.11 12.5 2.1 0.24 11.4 0.1 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Patched PF02460.18 VBB35069.1 - 1.2e-08 33.5 0.1 1.3e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 Patched family LPG_synthase_TM PF03706.13 VBB35069.1 - 0.0057 16.2 0.6 0.0068 16.0 0.6 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Phage_holin_3_6 PF07332.11 VBB35069.1 - 7.9 6.6 7.8 40 4.3 7.8 1.9 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 VBB35070.1 - 6.7e-48 163.3 0.0 8.3e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35070.1 - 2e-30 105.9 0.0 2.5e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 VBB35070.1 - 2.3e-05 23.5 0.1 2.9e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 VBB35070.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 VBB35070.1 - 0.0031 16.4 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 VBB35070.1 - 0.0053 16.1 0.2 0.0075 15.6 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB35070.1 - 0.0054 16.7 0.3 0.025 14.5 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 VBB35070.1 - 0.031 13.9 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 RIO1 family PXT1 PF15214.6 VBB35073.1 - 0.075 13.4 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal testis-specific protein 1 Cadherin PF00028.17 VBB35074.1 - 4.4e-09 36.7 0.1 3.6e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Cadherin domain XhlA PF10779.9 VBB35075.1 - 0.098 12.9 5.0 0.49 10.6 5.0 2.2 1 1 0 1 1 1 0 Haemolysin XhlA DUF2968 PF11180.8 VBB35075.1 - 8.2 6.0 13.8 3 7.5 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CDK5_activator PF03261.15 VBB35076.1 - 0.004 16.7 0.0 0.0043 16.7 0.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein tRNA_m1G_MT PF01746.21 VBB35077.1 - 1.2e-16 61.0 0.3 5.2e-16 58.9 0.0 2.0 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase KTI12 PF08433.10 VBB35077.1 - 0.6 9.5 6.1 5.1 6.5 0.0 2.8 1 1 0 2 2 2 0 Chromatin associated protein KTI12 OrfB_IS605 PF01385.19 VBB35077.1 - 1 9.6 5.3 3 8.1 5.3 1.9 1 0 0 1 1 1 0 Probable transposase C2 PF00168.30 VBB35078.1 - 1.6e-08 34.8 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.24 VBB35079.1 - 0.0044 15.9 11.5 0.13 11.0 2.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Transgly_assoc PF04226.13 VBB35079.1 - 0.011 16.0 2.6 0.35 11.2 0.3 2.8 2 0 0 2 2 2 0 Transglycosylase associated protein EF-hand_1 PF00036.32 VBB35080.1 - 2e-23 80.1 15.9 0.00019 20.8 0.0 6.4 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 VBB35080.1 - 6.3e-19 66.2 17.2 0.0012 18.6 0.1 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 VBB35080.1 - 2.2e-18 66.4 27.7 3.2e-06 27.5 0.8 4.7 1 1 5 6 6 6 6 EF-hand domain pair EF-hand_5 PF13202.6 VBB35080.1 - 6.5e-18 63.3 19.0 0.019 14.4 0.5 6.4 6 0 0 6 6 6 6 EF hand SPARC_Ca_bdg PF10591.9 VBB35080.1 - 1.6e-08 34.8 2.2 0.00099 19.4 0.2 3.3 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 VBB35080.1 - 1e-07 31.7 3.1 0.14 12.0 0.0 4.8 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 VBB35080.1 - 5.9e-07 29.2 16.8 0.05 13.5 0.1 5.8 5 1 1 6 6 6 2 EF-hand domain pair Multi_ubiq PF14452.6 VBB35080.1 - 0.0021 18.3 0.3 0.03 14.5 0.2 2.9 3 1 0 3 3 3 1 Multiubiquitin Dockerin_1 PF00404.18 VBB35080.1 - 0.42 10.9 7.6 5.8 7.2 0.0 3.4 3 2 1 4 4 4 0 Dockerin type I domain DUF724 PF05266.14 VBB35081.1 - 0.058 13.2 0.5 0.064 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PDEase_I PF00233.19 VBB35082.1 - 1.1e-65 221.7 2.8 1.3e-65 221.5 2.8 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Collagen PF01391.18 VBB35084.1 - 8.6e-12 44.6 37.4 2e-09 37.1 37.4 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M14 PF00246.24 VBB35085.1 - 6.9e-07 29.4 0.0 7.1e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase CUB PF00431.20 VBB35086.1 - 2.9e-05 24.4 0.0 4.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 CUB domain YlbE PF14003.6 VBB35087.1 - 0.066 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 YlbE-like protein Hamartin PF04388.12 VBB35087.1 - 0.098 11.3 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Hamartin protein PIN_4 PF13638.6 VBB35088.1 - 1.1e-06 28.9 0.4 8.2e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 PIN domain LBP_BPI_CETP PF01273.25 VBB35090.1 - 1e-10 41.5 0.8 1.6e-10 40.8 0.8 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain zf-C2H2 PF00096.26 VBB35091.1 - 0.0058 17.0 0.2 0.0058 17.0 0.2 2.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 VBB35091.1 - 0.08 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 VBB35091.1 - 0.15 13.0 0.2 0.15 13.0 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB35091.1 - 0.17 12.4 7.4 0.27 11.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain RhoGAP PF00620.27 VBB35096.1 - 7.6e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain PutA_N PF18083.1 VBB35096.1 - 0.016 15.2 0.0 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Proline utilization A N-terminal domain SH3_2 PF07653.17 VBB35096.1 - 0.059 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain AMP-binding PF00501.28 VBB35097.1 - 3e-21 75.5 0.0 4.2e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 VBB35097.1 - 3.3e-06 28.0 0.0 1e-05 26.4 0.0 2.0 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF150 PF02576.17 VBB35099.1 - 0.026 14.9 0.5 0.088 13.2 0.2 2.0 2 0 0 2 2 2 0 RimP N-terminal domain Amino_oxidase PF01593.24 VBB35099.1 - 0.054 12.8 0.2 0.069 12.4 0.2 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Swm2 PF17083.5 VBB35099.1 - 0.061 13.3 3.8 0.086 12.8 0.4 2.6 2 1 0 2 2 2 0 Nucleolar protein Swm2 NDUFB11 PF17250.2 VBB35099.1 - 0.086 13.5 0.0 0.68 10.6 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Chordopox_A13L PF05961.11 VBB35099.1 - 0.84 9.9 2.7 4 7.7 0.1 3.2 3 1 1 4 4 4 0 Chordopoxvirus A13L protein DASH_Dad3 PF08656.10 VBB35099.1 - 1.6 8.9 4.9 18 5.5 0.5 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad3 Baculo_PEP_C PF04513.12 VBB35099.1 - 3.7 7.6 8.2 5.9 6.9 0.3 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.9 VBB35099.1 - 5 7.2 8.6 5.8 7.0 0.2 3.5 3 0 0 3 3 3 0 Short coiled-coil protein Nbl1_Borealin_N PF10444.9 VBB35099.1 - 6 6.6 8.1 14 5.4 0.2 4.2 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal CGI-121 PF08617.10 VBB35100.1 - 0.022 14.9 1.0 0.03 14.5 1.0 1.3 1 0 0 1 1 1 0 Kinase binding protein CGI-121 DUF1759 PF03564.15 VBB35102.1 - 1.3e-05 25.2 0.6 1.5e-05 25.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) zf-H2C2_2 PF13465.6 VBB35103.1 - 1.3e-14 53.8 6.5 2.4e-08 34.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB35103.1 - 4.2e-14 52.1 7.4 4.4e-07 30.0 0.1 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB35103.1 - 1.7e-11 43.9 3.9 9.2e-06 26.1 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 VBB35103.1 - 9.7e-08 32.2 4.4 0.0047 17.3 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 VBB35103.1 - 2.5e-06 27.1 0.1 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 VBB35103.1 - 1.3e-05 25.0 2.9 0.028 14.4 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB35103.1 - 2.2e-05 24.6 6.6 0.006 16.8 0.1 2.8 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 VBB35103.1 - 0.0025 17.9 1.4 0.59 10.3 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain zf-MYST PF17772.1 VBB35103.1 - 0.0027 17.3 0.3 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain GAGA PF09237.11 VBB35103.1 - 0.004 16.9 0.4 0.011 15.6 0.2 1.9 1 1 1 2 2 2 1 GAGA factor zf-C2H2_2 PF12756.7 VBB35103.1 - 0.0054 17.0 1.7 2.4 8.6 0.0 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 VBB35103.1 - 0.0056 16.8 0.7 0.51 10.5 0.2 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.12 VBB35103.1 - 0.013 15.7 0.5 0.021 15.1 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 VBB35103.1 - 0.021 15.2 0.7 0.023 15.0 0.7 1.4 1 1 0 1 1 1 0 zinc-finger-containing domain PyrI_C PF02748.15 VBB35103.1 - 0.037 13.9 0.6 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 VBB35103.1 - 0.043 14.0 1.9 3.6 7.8 0.3 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger XPA_N PF01286.18 VBB35103.1 - 0.091 12.8 2.4 2.3 8.3 0.2 2.2 2 0 0 2 2 2 0 XPA protein N-terminal Actin_micro PF17003.5 VBB35103.1 - 0.12 11.6 1.1 0.8 8.8 0.1 1.9 1 1 1 2 2 2 0 Putative actin-like family C1_2 PF03107.16 VBB35103.1 - 0.19 12.1 3.5 1.9 8.8 3.5 2.2 1 1 0 1 1 1 0 C1 domain Desulfoferrod_N PF06397.12 VBB35103.1 - 0.26 10.9 1.9 1 9.0 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-H2C2_5 PF13909.6 VBB35103.1 - 5 7.0 18.6 1.1 9.0 0.7 3.8 3 2 0 3 3 3 0 C2H2-type zinc-finger domain LPD11 PF18824.1 VBB35104.1 - 0.18 11.9 2.3 1.5 9.0 0.5 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Gal-bind_lectin PF00337.22 VBB35106.1 - 7.2e-20 70.9 0.0 8.1e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin TPR_1 PF00515.28 VBB35107.1 - 0.00057 19.6 0.8 0.054 13.3 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB35107.1 - 0.00095 19.1 0.4 0.024 14.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 VBB35107.1 - 0.012 15.9 0.1 0.6 10.4 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 VBB35107.1 - 0.021 14.5 0.9 0.1 12.3 0.8 2.1 1 1 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 VBB35107.1 - 0.047 14.3 0.0 0.077 13.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 VBB35107.1 - 0.05 13.8 3.2 0.14 12.4 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 VBB35107.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 SHNi-TPR NOA36 PF06524.12 VBB35108.1 - 0.13 11.6 24.6 0.16 11.3 24.6 1.2 1 0 0 1 1 1 0 NOA36 protein TSKS PF15358.6 VBB35108.1 - 0.14 10.5 6.6 0.16 10.3 6.6 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate EGF_3 PF12947.7 VBB35109.1 - 3.6e-17 62.3 25.8 6.5e-07 29.5 6.0 3.6 3 1 0 3 3 3 3 EGF domain hEGF PF12661.7 VBB35109.1 - 9.8e-15 54.6 23.8 9.7e-05 22.9 4.3 4.1 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_CA PF07645.15 VBB35109.1 - 5.7e-14 52.0 30.2 2.8e-05 24.2 0.8 3.8 2 1 1 4 4 4 3 Calcium-binding EGF domain EGF PF00008.27 VBB35109.1 - 6.9e-13 48.6 27.5 4.2e-05 23.8 4.0 3.7 3 1 0 3 3 3 3 EGF-like domain VWA PF00092.28 VBB35109.1 - 1.1e-12 48.6 0.2 1.5e-12 48.1 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 VBB35109.1 - 8e-09 35.6 26.6 0.0012 19.1 2.7 3.6 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 VBB35109.1 - 6.6e-08 32.5 25.3 0.00062 19.8 2.2 4.0 4 0 0 4 4 4 3 MSP1 EGF domain 1 cEGF PF12662.7 VBB35109.1 - 3.7e-06 26.7 19.4 0.0034 17.3 0.3 4.2 4 0 0 4 4 4 3 Complement Clr-like EGF-like VWA_2 PF13519.6 VBB35109.1 - 0.00021 21.9 0.0 0.00039 21.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain HipN PF18253.1 VBB35109.1 - 0.17 11.6 0.7 0.4 10.4 0.7 1.6 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Plasmod_Pvs28 PF06247.11 VBB35109.1 - 0.46 10.8 29.7 0.2 12.0 2.8 3.7 4 0 0 4 4 4 0 Pvs28 EGF domain Whirly PF08536.11 VBB35112.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Whirly transcription factor Y_phosphatase PF00102.27 VBB35115.1 - 3.6e-27 95.4 0.2 4.2e-27 95.2 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 VBB35115.1 - 0.00013 22.0 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 VBB35115.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 VBB35115.1 - 0.077 12.8 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain rve PF00665.26 VBB35116.1 - 6.6e-21 74.7 0.1 1.7e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 VBB35116.1 - 5.1e-19 68.7 0.4 8e-17 61.5 0.4 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 VBB35116.1 - 4.9e-15 55.4 2.4 6.2e-15 55.0 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB35116.1 - 2.8e-06 27.4 0.0 8.9e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 VBB35116.1 - 0.00095 18.9 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PapB PF03333.13 VBB35116.1 - 0.094 12.8 0.0 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein fn3 PF00041.21 VBB35117.1 - 1.3e-05 25.4 0.0 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III domain SH3_9 PF14604.6 VBB35118.1 - 2.8e-08 33.5 0.0 5.3e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 VBB35118.1 - 5e-08 32.5 0.0 8.6e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 VBB35118.1 - 1.9e-07 30.6 0.0 2.6e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 SH3 domain PG_binding_4 PF12229.8 VBB35118.1 - 0.037 14.3 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF1380 PF07128.12 VBB35118.1 - 0.052 13.7 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) FliMN_C PF01052.20 VBB35118.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Glyco_hydro_31 PF01055.26 VBB35123.1 - 2.1e-75 254.6 0.1 2.4e-75 254.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Collagen PF01391.18 VBB35124.1 - 5.2e-16 58.2 60.0 0.18 11.6 60.0 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-RING_2 PF13639.6 VBB35125.1 - 2.5e-11 43.7 12.7 7.8e-10 38.9 8.2 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 VBB35125.1 - 1.6e-07 30.9 4.3 4.4e-07 29.5 4.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 VBB35125.1 - 7.5e-05 22.5 14.2 0.00022 21.0 7.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PRP21_like_P PF12230.8 VBB35125.1 - 0.00037 20.4 0.1 0.0004 20.3 0.1 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zf-RING_UBOX PF13445.6 VBB35125.1 - 0.00052 20.0 8.0 0.00052 20.0 8.0 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 VBB35125.1 - 0.00067 19.6 13.3 0.015 15.3 7.3 2.4 2 0 0 2 2 2 2 zinc-RING finger domain FANCL_C PF11793.8 VBB35125.1 - 0.00075 19.6 9.6 0.041 14.1 4.5 2.6 2 1 0 2 2 2 2 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 VBB35125.1 - 0.004 16.8 4.4 0.004 16.8 4.4 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 VBB35125.1 - 0.0053 17.0 13.3 0.0097 16.2 8.9 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain RINGv PF12906.7 VBB35125.1 - 0.01 15.9 5.7 0.01 15.9 5.7 2.4 2 2 0 2 2 2 0 RING-variant domain zf-C3HC4 PF00097.25 VBB35125.1 - 0.011 15.6 15.3 0.012 15.4 8.6 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 VBB35125.1 - 0.024 15.1 1.2 0.81 10.2 0.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_3 PF13920.6 VBB35125.1 - 0.03 14.2 14.5 0.33 10.8 6.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RNF220 PF15926.5 VBB35125.1 - 0.056 13.1 0.7 0.073 12.7 0.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-RING-like PF08746.11 VBB35125.1 - 7.5 7.0 14.2 0.27 11.6 5.9 2.5 2 1 0 2 2 2 0 RING-like domain SNARE PF05739.19 VBB35126.1 - 8.2e-06 25.7 4.6 8.2e-06 25.7 4.6 2.2 2 1 0 2 2 2 1 SNARE domain ShK PF01549.24 VBB35127.1 - 2.7e-20 72.6 19.0 4.6e-10 39.9 4.7 2.6 2 0 0 2 2 2 2 ShK domain-like FSA_C PF10479.9 VBB35127.1 - 0.087 10.9 9.9 0.1 10.7 9.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2722 PF10846.8 VBB35128.1 - 0.0017 17.4 13.7 0.002 17.1 13.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4175 PF13779.6 VBB35128.1 - 0.04 11.8 10.2 0.043 11.7 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Dala_Dala_lig_N PF01820.21 VBB35128.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Lin-8 PF03353.15 VBB35128.1 - 0.19 11.3 9.9 0.27 10.8 9.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 VBB35128.1 - 0.41 9.4 4.1 0.43 9.3 4.1 1.1 1 0 0 1 1 1 0 Presenilin MMPL PF03176.15 VBB35128.1 - 0.65 8.9 3.0 0.84 8.5 3.0 1.1 1 0 0 1 1 1 0 MMPL family DUF4834 PF16118.5 VBB35128.1 - 4.4 8.3 8.0 8 7.5 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) F-box-like PF12937.7 VBB35131.1 - 5.3e-10 39.0 0.5 1.4e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 VBB35131.1 - 5.8e-06 26.0 1.9 7.2e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.6 VBB35131.1 - 0.0099 15.8 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like domain Phosphodiest PF01663.22 VBB35132.1 - 1.6e-20 74.0 1.0 1.8e-20 73.8 1.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Zip PF02535.22 VBB35133.1 - 8.3e-18 64.7 5.8 9e-18 64.6 5.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MpPF26 PF07666.11 VBB35133.1 - 0.0052 16.9 2.1 0.0071 16.5 2.1 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 26 Phage_holin_5_2 PF16079.5 VBB35133.1 - 0.27 11.6 3.0 0.99 9.8 0.1 2.3 1 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Cytochrome-c551 PF10643.9 VBB35133.1 - 0.28 10.7 3.2 0.44 10.1 3.2 1.4 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF2085 PF09858.9 VBB35133.1 - 0.9 10.0 3.6 2.7 8.5 3.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2085) EGF_3 PF12947.7 VBB35134.1 - 3.4e-18 65.5 44.4 6e-05 23.1 7.8 4.6 4 0 0 4 4 4 4 EGF domain EGF_CA PF07645.15 VBB35134.1 - 2e-14 53.5 42.9 2.8e-05 24.2 7.7 4.6 4 1 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.27 VBB35134.1 - 4.6e-14 52.4 43.8 5.2e-06 26.7 5.7 5.0 4 3 0 4 4 4 4 EGF-like domain hEGF PF12661.7 VBB35134.1 - 5.8e-11 42.6 41.2 0.00017 22.1 1.6 6.0 6 0 0 6 6 6 4 Human growth factor-like EGF cEGF PF12662.7 VBB35134.1 - 2.9e-07 30.3 25.3 0.098 12.6 0.5 5.5 4 1 0 4 4 4 4 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 VBB35134.1 - 2.3e-06 27.6 30.9 0.00012 22.0 4.3 4.5 4 0 0 4 4 4 2 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 VBB35134.1 - 1.9e-05 24.9 43.8 0.023 15.0 2.8 4.8 4 1 0 4 4 4 3 Pvs28 EGF domain FXa_inhibition PF14670.6 VBB35134.1 - 7.4e-05 22.9 48.5 0.27 11.6 7.3 4.9 4 1 0 4 4 4 4 Coagulation Factor Xa inhibitory site Toxin_32 PF08120.11 VBB35134.1 - 0.01 15.6 1.1 0.01 15.6 1.1 3.8 4 1 0 4 4 4 0 Tamulustoxin family Ion_trans_2 PF07885.16 VBB35137.1 - 2.2e-15 56.4 2.5 2.2e-15 56.4 2.5 1.5 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 VBB35137.1 - 8.8e-15 54.6 2.5 1e-14 54.4 2.5 1.0 1 0 0 1 1 1 1 Ion transport protein DUF2798 PF11391.8 VBB35137.1 - 0.011 15.7 1.1 0.017 15.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) PKD_channel PF08016.12 VBB35137.1 - 0.03 13.0 0.6 0.031 13.0 0.6 1.0 1 0 0 1 1 1 0 Polycystin cation channel SecE PF00584.20 VBB35137.1 - 0.05 13.5 2.0 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Ion_trans PF00520.31 VBB35138.1 - 4e-16 59.0 3.9 4.8e-16 58.7 3.9 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 VBB35138.1 - 6.2e-13 48.5 8.8 8.6e-13 48.1 8.8 1.2 1 0 0 1 1 1 1 Ion channel Cytochrom_B_C PF00032.17 VBB35138.1 - 0.0028 17.9 1.2 0.0036 17.6 1.2 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD COX2-transmemb PF09125.10 VBB35138.1 - 0.034 14.0 2.2 0.073 12.9 2.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DUF3169 PF11368.8 VBB35139.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1759 PF03564.15 VBB35140.1 - 0.17 11.8 2.2 1.2 9.0 1.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) APG6_N PF17675.1 VBB35141.1 - 0.34 11.5 7.2 0.42 11.1 7.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Zona_pellucida PF00100.23 VBB35142.1 - 3.4e-05 23.8 0.4 4.2e-05 23.5 0.4 1.3 1 1 0 1 1 1 1 Zona pellucida-like domain TSC22 PF01166.18 VBB35144.1 - 8.7e-25 86.8 2.7 1e-24 86.5 2.7 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family Shugoshin_N PF07558.11 VBB35144.1 - 0.0006 19.6 0.1 0.00089 19.1 0.1 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region SOGA PF11365.8 VBB35144.1 - 0.02 16.0 0.1 0.025 15.7 0.1 1.3 1 0 0 1 1 1 0 Protein SOGA bZIP_2 PF07716.15 VBB35144.1 - 0.097 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Motile_Sperm PF00635.26 VBB35147.1 - 4.7e-23 81.1 0.0 5.2e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Motile_Sperm PF00635.26 VBB35148.1 - 6.6e-23 80.6 0.0 7.5e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain E1-E2_ATPase PF00122.20 VBB35151.1 - 1.8e-24 86.3 0.8 1.8e-24 86.3 0.8 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 VBB35151.1 - 1.7e-16 59.7 0.0 3.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cwf_Cwc_15 PF04889.12 VBB35152.1 - 9.4 5.9 17.5 9.1 5.9 17.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EGF_3 PF12947.7 VBB35153.1 - 4.9e-06 26.6 30.7 0.0014 18.8 7.6 3.5 3 0 0 3 3 3 2 EGF domain EGF_CA PF07645.15 VBB35153.1 - 3.2e-05 24.0 31.9 0.00069 19.8 3.7 3.3 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF PF00008.27 VBB35153.1 - 0.0018 18.5 27.8 0.03 14.6 8.0 3.7 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 VBB35153.1 - 0.011 16.3 4.4 0.011 16.3 4.4 4.1 4 1 0 4 4 4 0 Human growth factor-like EGF Collagen PF01391.18 VBB35154.1 - 1.1e-06 28.3 16.2 1.1e-06 28.3 16.2 1.4 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) PDH PF02153.17 VBB35155.1 - 0.12 11.4 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase Carn_acyltransf PF00755.20 VBB35156.1 - 6.3e-69 233.1 0.1 7e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cullin PF00888.22 VBB35157.1 - 0.0044 15.7 0.3 0.007 15.0 0.1 1.3 1 1 0 1 1 1 1 Cullin family DNA_primase_S PF01896.19 VBB35157.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 DNA primase small subunit PTEN_C2 PF10409.9 VBB35159.1 - 1e-11 44.7 1.4 1.4e-11 44.3 1.4 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Pkinase PF00069.25 VBB35160.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35160.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RBD PF02196.15 VBB35161.1 - 0.00015 21.8 0.0 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 Raf-like Ras-binding domain Peptidase_C1 PF00112.23 VBB35162.1 - 1.6e-32 113.3 0.0 3e-32 112.5 0.0 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 VBB35162.1 - 1.8e-08 34.7 0.1 4.1e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 VBB35162.1 - 0.023 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family MBOAT PF03062.19 VBB35163.1 - 5.8e-06 25.9 9.8 1.3e-05 24.8 9.9 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Anoct_dimer PF16178.5 VBB35163.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Microcin PF03526.13 VBB35164.1 - 0.18 11.7 0.0 0.45 10.4 0.0 1.6 2 0 0 2 2 2 0 Colicin E1 (microcin) immunity protein DB PF01682.19 VBB35165.1 - 3e-06 27.5 1.8 3.3e-06 27.3 1.8 1.0 1 0 0 1 1 1 1 DB module PDZ PF00595.24 VBB35167.1 - 8.9e-11 42.0 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB35167.1 - 6.7e-09 35.5 0.0 8.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB35167.1 - 0.056 13.8 0.1 0.13 12.6 0.1 1.6 1 1 0 2 2 2 0 PDZ domain SUIM_assoc PF16619.5 VBB35169.1 - 0.42 10.7 11.3 1.1 9.4 11.0 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 VBB35169.1 - 0.53 10.2 24.2 0.62 10.0 24.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HCO3_cotransp PF00955.21 VBB35170.1 - 1.2e-65 222.3 0.2 1.3e-65 222.2 0.2 1.0 1 0 0 1 1 1 1 HCO3- transporter family Colicin_K PF17500.2 VBB35170.1 - 0.047 14.2 0.5 0.078 13.5 0.5 1.3 1 0 0 1 1 1 0 Colicin-K Sh_2 PF17512.2 VBB35170.1 - 0.051 13.4 0.7 0.33 10.7 0.2 2.1 2 1 0 2 2 2 0 Metapneumovirus Small hydrophobic protein EB PF01683.18 VBB35175.1 - 3.3e-06 27.3 1.0 3.3e-06 27.3 1.0 1.3 1 1 0 1 1 1 1 EB module Neuroparsin PF07327.11 VBB35175.1 - 0.00079 19.8 0.8 0.00091 19.6 0.8 1.1 1 0 0 1 1 1 1 Neuroparsin Pkinase PF00069.25 VBB35176.1 - 3.2e-38 131.6 0.0 3.8e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35176.1 - 1.4e-14 54.0 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB35176.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 VBB35176.1 - 0.011 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 VBB35176.1 - 0.011 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 VBB35176.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 VBB35176.1 - 0.22 10.9 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2-set PF05790.15 VBB35177.1 - 0.083 13.1 1.1 0.18 12.0 1.1 1.5 1 0 0 1 1 1 0 Immunoglobulin C2-set domain PHO4 PF01384.20 VBB35178.1 - 1.5e-27 96.6 0.0 1.5e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family FPP PF05911.11 VBB35178.1 - 0.12 10.6 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil PAN_1 PF00024.26 VBB35179.1 - 2.2e-11 43.5 1.3 3.1e-11 43.1 0.4 1.7 1 1 1 2 2 2 1 PAN domain Carb_anhydrase PF00194.21 VBB35180.1 - 6.2e-45 153.7 0.0 7.2e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Y_phosphatase PF00102.27 VBB35182.1 - 2.5e-16 60.0 0.1 3e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 VBB35182.1 - 0.00012 21.9 2.6 0.0005 19.9 0.6 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 VBB35182.1 - 0.0088 16.0 0.0 0.01 15.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2972 PF11186.8 VBB35182.1 - 0.011 15.6 1.4 0.85 9.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) FliG_M PF14841.6 VBB35182.1 - 0.013 15.7 0.3 0.023 14.9 0.3 1.6 1 1 0 1 1 1 0 FliG middle domain Phage_int_SAM_5 PF13102.6 VBB35182.1 - 0.038 14.3 0.1 0.044 14.1 0.1 1.1 1 0 0 1 1 1 0 Phage integrase SAM-like domain TarH PF02203.15 VBB35182.1 - 0.041 13.8 0.1 0.069 13.1 0.1 1.3 1 1 0 1 1 1 0 Tar ligand binding domain homologue DUF1796 PF08795.10 VBB35182.1 - 0.048 13.6 0.8 1.6 8.6 0.1 2.0 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) PPDK_N PF01326.19 VBB35182.1 - 0.096 11.9 0.2 0.092 12.0 0.2 1.0 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Pkinase PF00069.25 VBB35183.1 - 6.6e-21 74.8 0.0 7.2e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35183.1 - 1.2e-12 47.7 0.0 1.4e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB35183.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_N PF09379.10 VBB35184.1 - 2.8e-09 36.8 0.1 4.9e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 VBB35184.1 - 1.4e-06 28.7 0.0 3.6e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 FERM central domain UPA PF17217.3 VBB35184.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 UPA domain DUF4248 PF14053.6 VBB35184.1 - 0.083 12.9 0.4 0.25 11.4 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4248) CUB PF00431.20 VBB35186.1 - 1.2e-24 86.7 0.0 1.8e-24 86.2 0.0 1.3 1 1 0 1 1 1 1 CUB domain CUB_2 PF02408.20 VBB35186.1 - 0.025 14.3 0.1 0.076 12.8 0.1 2.0 1 1 0 1 1 1 0 CUB-like domain DUF1372 PF07116.11 VBB35186.1 - 0.11 12.6 0.0 2 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) Spt20 PF12090.8 VBB35187.1 - 0.0038 16.9 17.3 0.004 16.8 17.3 1.1 1 0 0 1 1 1 1 Spt20 family DUF4643 PF15485.6 VBB35187.1 - 0.046 13.6 4.4 0.052 13.4 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Peptidase_S15 PF02129.18 VBB35187.1 - 0.055 13.0 3.7 0.065 12.8 3.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SurA_N_2 PF13623.6 VBB35187.1 - 0.27 11.1 16.2 0.32 10.9 16.2 1.2 1 0 0 1 1 1 0 SurA N-terminal domain TFIIA PF03153.13 VBB35187.1 - 0.3 11.0 18.8 0.31 11.0 18.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.11 VBB35187.1 - 0.32 10.4 10.7 0.37 10.1 10.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Band_3_cyto PF07565.13 VBB35187.1 - 1.2 8.9 6.8 1.3 8.8 6.8 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 VBB35187.1 - 2.6 6.8 6.2 2.7 6.7 6.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2722 PF10846.8 VBB35187.1 - 3.2 6.6 18.5 3.6 6.4 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 VBB35187.1 - 4.3 6.0 6.3 4.4 5.9 6.3 1.0 1 0 0 1 1 1 0 Presenilin EGF_3 PF12947.7 VBB35188.1 - 4.3e-15 55.6 47.5 8.8e-07 29.0 6.0 5.9 5 0 0 5 5 5 3 EGF domain EGF PF00008.27 VBB35188.1 - 1.7e-14 53.8 53.2 3.8e-05 23.9 3.5 6.0 6 1 0 6 6 6 5 EGF-like domain EGF_CA PF07645.15 VBB35188.1 - 1e-13 51.2 51.1 3.6e-05 23.9 6.9 5.9 4 1 0 5 5 5 4 Calcium-binding EGF domain hEGF PF12661.7 VBB35188.1 - 5e-11 42.8 49.8 9.8e-05 22.8 3.9 7.4 7 0 0 7 7 7 3 Human growth factor-like EGF cEGF PF12662.7 VBB35188.1 - 8.6e-06 25.6 32.3 0.0046 16.9 0.3 6.3 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 VBB35188.1 - 1.9e-05 24.6 39.5 0.00085 19.3 2.2 5.8 6 0 0 6 6 6 3 MSP1 EGF domain 1 FXa_inhibition PF14670.6 VBB35188.1 - 3.2e-05 24.1 51.3 0.034 14.4 3.0 5.9 4 1 1 5 5 5 3 Coagulation Factor Xa inhibitory site VWA PF00092.28 VBB35188.1 - 0.013 15.8 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain ShK PF01549.24 VBB35189.1 - 2.3e-08 34.4 6.6 2.7e-08 34.2 6.6 1.1 1 0 0 1 1 1 1 ShK domain-like PLAC PF08686.11 VBB35189.1 - 0.0051 17.5 0.8 0.007 17.1 0.8 1.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain zf-CCCH PF00642.24 VBB35190.1 - 4.2e-08 32.9 1.1 6.6e-08 32.3 1.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 VBB35190.1 - 0.0002 21.1 1.3 0.00031 20.5 1.3 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 VBB35190.1 - 0.0014 18.6 1.0 0.004 17.2 1.0 1.8 1 1 0 1 1 1 1 Zinc finger domain Telethonin PF09470.10 VBB35190.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Telethonin protein Torus PF16131.5 VBB35190.1 - 0.38 11.4 2.2 2.9 8.6 0.4 2.8 2 1 1 3 3 3 0 Torus domain SP_C-Propep PF08999.10 VBB35191.1 - 0.022 14.5 3.2 0.024 14.4 3.2 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Band_3_cyto PF07565.13 VBB35192.1 - 1.7e-40 139.5 0.0 2e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain SNF PF00209.18 VBB35193.1 - 4.5e-68 230.2 10.6 5e-68 230.1 10.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4969 PF16339.5 VBB35195.1 - 0.14 12.5 1.1 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) rve_2 PF13333.6 VBB35196.1 - 0.19 11.9 2.8 3 8.1 0.2 2.5 2 0 0 2 2 2 0 Integrase core domain Folate_carrier PF01770.18 VBB35197.1 - 4.4e-50 170.6 13.7 5.4e-50 170.3 13.7 1.1 1 0 0 1 1 1 1 Reduced folate carrier DUF3630 PF12305.8 VBB35197.1 - 0.2 11.8 2.4 5.2 7.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3630) Gal_Lectin PF02140.18 VBB35199.1 - 3.3e-13 49.9 2.6 4.5e-13 49.4 2.6 1.2 1 0 0 1 1 1 1 Galactose binding lectin domain HTH_16 PF12645.7 VBB35199.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Collagen PF01391.18 VBB35201.1 - 1.2e-11 44.2 37.3 2.7e-09 36.6 37.3 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Fungus-induced PF10917.8 VBB35201.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Fungus-induced protein An_peroxidase PF03098.15 VBB35205.1 - 9e-49 166.4 0.0 1.2e-48 166.0 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase RasGEF PF00617.19 VBB35207.1 - 1.1e-15 58.3 0.2 1.2e-15 58.2 0.2 1.0 1 0 0 1 1 1 1 RasGEF domain Inhibitor_I29 PF08246.12 VBB35208.1 - 4.5e-05 23.8 0.0 8.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 VBB35208.1 - 0.00033 20.8 0.0 0.00067 19.8 0.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease CobT PF06213.12 VBB35210.1 - 1.5 8.2 23.2 1.7 8.0 23.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Collagen PF01391.18 VBB35212.1 - 0.0011 18.6 17.9 0.0012 18.6 17.9 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB35213.1 - 3.1e-06 26.8 16.2 3.8e-06 26.6 16.2 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) LPAM_2 PF13627.6 VBB35213.1 - 0.011 15.5 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site RBD PF02196.15 VBB35215.1 - 6e-05 23.0 0.0 8.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Raf-like Ras-binding domain BH4 PF02180.17 VBB35215.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 C1_1 PF00130.22 VBB35216.1 - 4.4e-05 23.3 0.5 6.6e-05 22.7 0.5 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Chromadorea_ALT PF05535.12 VBB35218.1 - 6.9e-33 112.7 8.6 6.9e-33 112.7 8.6 1.6 2 0 0 2 2 2 1 Chromadorea ALT protein Ion_trans PF00520.31 VBB35219.1 - 1.1e-19 70.7 10.4 1.3e-19 70.4 10.4 1.1 1 0 0 1 1 1 1 Ion transport protein rve PF00665.26 VBB35220.1 - 3.1e-09 37.1 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF5641 PF18701.1 VBB35220.1 - 4.2e-09 36.5 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 VBB35220.1 - 1.4e-07 31.5 0.2 3.1e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB35220.1 - 0.091 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 VBB35221.1 - 1.4e-37 129.4 0.1 3.1e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD PF00628.29 VBB35221.1 - 1.3e-06 28.2 7.3 2.8e-06 27.1 7.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 VBB35221.1 - 0.01 15.4 2.1 0.021 14.4 2.1 1.5 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 VBB35221.1 - 0.049 13.8 6.8 0.15 12.3 6.8 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 VBB35221.1 - 0.39 10.9 2.0 1.7 8.9 2.0 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Cpn60_TCP1 PF00118.24 VBB35221.1 - 0.46 9.0 3.4 0.77 8.3 3.4 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family C1_1 PF00130.22 VBB35221.1 - 1 9.3 8.9 0.15 12.0 4.1 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CLASP_N PF12348.8 VBB35224.1 - 0.0001 21.9 1.1 0.00012 21.8 1.1 1.0 1 0 0 1 1 1 1 CLASP N terminal NUC173 PF08161.12 VBB35224.1 - 0.0053 16.4 0.2 0.01 15.5 0.2 1.5 1 1 0 1 1 1 1 NUC173 domain Sec7_N PF12783.7 VBB35224.1 - 0.032 14.1 0.2 0.051 13.5 0.1 1.4 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ParcG PF10274.9 VBB35224.1 - 0.072 13.2 0.1 0.096 12.8 0.1 1.4 1 1 0 1 1 1 0 Parkin co-regulated protein DEK_C PF08766.11 VBB35224.1 - 0.1 12.5 0.7 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 DEK C terminal domain Plasmod_dom_1 PF09715.10 VBB35224.1 - 0.11 12.5 0.7 0.28 11.3 0.4 1.8 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Adaptin_N PF01602.20 VBB35225.1 - 3.2e-43 148.1 0.1 3.5e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 VBB35225.1 - 0.0001 22.4 0.1 0.0003 20.9 0.0 1.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 VBB35225.1 - 0.023 15.0 0.3 0.42 11.0 0.0 2.4 2 1 1 3 3 3 0 HEAT repeats DUF5641 PF18701.1 VBB35226.1 - 6e-11 42.4 0.1 1.8e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5641) DUF810 PF05664.11 VBB35226.1 - 0.041 12.4 0.4 0.35 9.4 0.1 1.9 1 1 1 2 2 2 0 Plant family of unknown function (DUF810) TUDOR PF00567.24 VBB35228.1 - 5.9e-07 29.6 0.0 7.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Tudor domain SL4P PF17618.2 VBB35228.1 - 0.085 12.9 0.1 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein FAR1 PF03101.15 VBB35228.1 - 0.098 13.4 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain Ion_trans_2 PF07885.16 VBB35230.1 - 4e-09 36.3 15.8 7.6e-08 32.2 9.0 2.2 2 0 0 2 2 2 2 Ion channel Pkinase_C PF00433.24 VBB35232.1 - 4.1e-10 40.2 2.1 7e-10 39.5 2.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Myosin_head PF00063.21 VBB35233.1 - 1e-66 225.6 3.8 1.5e-66 225.0 3.8 1.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 VBB35236.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain ABM PF03992.16 VBB35236.1 - 0.034 14.2 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Sushi PF00084.20 VBB35238.1 - 4.3e-13 49.6 1.5 1e-07 32.4 0.1 3.3 2 1 1 3 3 3 3 Sushi repeat (SCR repeat) F5_F8_type_C PF00754.25 VBB35238.1 - 3.2e-10 40.2 0.0 5.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Proteasom_PSMB PF10508.9 VBB35239.1 - 0.033 12.7 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Collagen PF01391.18 VBB35240.1 - 2.1e-11 43.4 28.1 2.7e-11 43.1 28.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB35241.1 - 5.6e-10 38.8 27.5 6.6e-10 38.6 27.5 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TMEM154 PF15102.6 VBB35242.1 - 0.028 14.3 6.6 0.029 14.3 6.6 1.1 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 VBB35242.1 - 0.051 13.9 4.6 0.056 13.7 4.6 1.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF5113 PF17140.4 VBB35242.1 - 0.058 13.2 1.3 0.062 13.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Pox_EPC_I2-L1 PF12575.8 VBB35242.1 - 0.074 13.3 5.1 0.097 12.9 5.1 1.3 1 1 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF5383 PF17355.2 VBB35242.1 - 0.11 12.9 2.6 0.13 12.7 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Synaptobrevin PF00957.21 VBB35242.1 - 0.11 12.3 4.8 0.14 12.0 4.8 1.3 1 0 0 1 1 1 0 Synaptobrevin Tmemb_9 PF05434.11 VBB35242.1 - 0.12 12.2 7.7 0.16 11.9 7.7 1.2 1 0 0 1 1 1 0 TMEM9 Baculo_11_kDa PF06143.11 VBB35242.1 - 0.14 11.7 7.5 0.14 11.7 7.5 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3357 PF11837.8 VBB35242.1 - 0.23 11.9 1.2 0.24 11.9 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4448 PF14610.6 VBB35242.1 - 0.61 9.8 3.4 0.61 9.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Amnionless PF14828.6 VBB35242.1 - 0.66 8.7 3.2 0.67 8.7 3.2 1.0 1 0 0 1 1 1 0 Amnionless ASFV_J13L PF05568.11 VBB35242.1 - 0.94 9.2 5.0 1.1 9.0 5.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein AMA-1 PF02430.15 VBB35242.1 - 1.5 7.7 4.5 1.6 7.6 4.5 1.0 1 0 0 1 1 1 0 Apical membrane antigen 1 UPF0258 PF06789.12 VBB35242.1 - 1.9 8.6 9.7 2.1 8.4 9.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF3827 PF12877.7 VBB35242.1 - 2.3 6.5 8.6 2.3 6.5 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) LRR19-TM PF15176.6 VBB35242.1 - 2.5 8.1 4.1 2.6 8.1 4.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Shisa PF13908.6 VBB35242.1 - 2.9 8.1 10.3 3.1 8.0 10.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RIFIN PF02009.16 VBB35242.1 - 3.3 7.5 9.7 3.5 7.4 9.7 1.1 1 0 0 1 1 1 0 Rifin HemY_N PF07219.13 VBB35242.1 - 3.4 7.9 7.3 4 7.7 7.3 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Protocadherin PF08374.11 VBB35242.1 - 4.2 7.3 8.1 4.5 7.2 8.1 1.1 1 0 0 1 1 1 0 Protocadherin Sporozoite_P67 PF05642.11 VBB35243.1 - 0.029 12.5 0.3 0.037 12.1 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt20 PF12090.8 VBB35244.1 - 0.076 12.6 29.3 0.11 12.1 29.3 1.3 1 0 0 1 1 1 0 Spt20 family Velvet PF11754.8 VBB35244.1 - 0.28 11.1 12.4 0.29 11.0 12.4 1.0 1 0 0 1 1 1 0 Velvet factor Pex14_N PF04695.13 VBB35244.1 - 0.82 10.3 15.6 0.92 10.2 15.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 VBB35244.1 - 1.2 9.1 28.2 1.3 8.9 28.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 VBB35244.1 - 1.4 8.9 12.2 1.7 8.6 12.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Activator_LAG-3 PF11498.8 VBB35244.1 - 2.9 6.8 38.6 3.1 6.7 38.6 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ank_2 PF12796.7 VBB35246.1 - 3e-28 98.2 0.0 3.6e-12 46.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 VBB35246.1 - 6.4e-21 73.8 0.3 0.00059 20.2 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 VBB35246.1 - 5e-20 69.5 0.4 0.0036 17.7 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 VBB35246.1 - 6e-19 68.2 0.4 1.1e-05 25.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB35246.1 - 2.1e-18 66.1 1.3 0.00077 19.7 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Peptidase_A17 PF05380.13 VBB35249.1 - 4.6e-16 59.3 1.0 1.4e-15 57.6 1.0 1.9 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 VBB35249.1 - 1.2e-09 38.0 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C1_1 PF00130.22 VBB35250.1 - 2.5e-24 84.9 19.5 4e-17 61.8 8.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 VBB35250.1 - 0.00031 20.8 9.2 0.12 12.5 0.7 2.3 2 0 0 2 2 2 2 KIAA1045 RING finger C1_2 PF03107.16 VBB35250.1 - 0.017 15.4 14.5 0.9 9.9 6.7 2.7 2 0 0 2 2 2 0 C1 domain PHD_4 PF16866.5 VBB35250.1 - 0.11 12.6 8.6 1.2 9.3 1.0 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 VBB35250.1 - 0.12 12.4 17.8 0.91 9.5 5.7 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 VBB35250.1 - 0.19 11.6 18.4 0.25 11.3 2.3 2.6 2 0 0 2 2 2 0 PHD-finger DUF2321 PF10083.9 VBB35250.1 - 0.41 10.3 4.6 0.13 11.9 1.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) ADK_lid PF05191.14 VBB35250.1 - 0.88 9.6 0.1 0.88 9.6 0.1 3.4 3 1 1 4 4 4 0 Adenylate kinase, active site lid PDZ PF00595.24 VBB35251.1 - 1.5e-13 50.9 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB35251.1 - 3e-11 43.0 0.0 4.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 VBB35251.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 VBB35253.1 - 7.4e-17 61.5 0.2 8.6e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 VBB35254.1 - 3.6e-27 95.4 0.1 4.5e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35254.1 - 3.5e-21 75.6 0.0 4.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Hrs_helical PF12210.8 VBB35254.1 - 0.012 16.1 0.0 0.051 14.1 0.0 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate APOBEC4_like PF18774.1 VBB35254.1 - 0.086 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Metallophos PF00149.28 VBB35255.1 - 3.7e-18 66.8 0.0 5.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 VBB35255.1 - 0.0042 17.3 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 VBB35255.1 - 0.0058 17.0 0.2 0.016 15.6 0.2 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Nop14 PF04147.12 VBB35255.1 - 1.1 7.4 8.3 1.2 7.2 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 VBB35255.1 - 2.1 7.6 9.7 3.1 7.0 9.7 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 VBB35255.1 - 7.1 6.3 15.3 13 5.4 15.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 VBB35255.1 - 8.2 4.4 15.7 11 4.0 15.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPN6_N PF18055.1 VBB35257.1 - 1.5e-05 25.3 1.8 0.0014 19.0 0.0 2.0 1 1 1 2 2 2 2 26S proteasome regulatory subunit RPN6 N-terminal domain Spot_14 PF07084.12 VBB35257.1 - 0.037 14.2 0.5 0.14 12.3 0.5 1.8 1 1 1 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 DUF1456 PF07308.13 VBB35257.1 - 0.15 12.4 0.8 1 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Patched PF02460.18 VBB35258.1 - 4e-20 71.5 0.5 4.6e-20 71.3 0.5 1.0 1 0 0 1 1 1 1 Patched family FixQ PF05545.11 VBB35258.1 - 1.6 8.8 6.0 2.6 8.1 6.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF2195 PF09961.9 VBB35259.1 - 0.032 14.2 6.9 0.51 10.3 2.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) DUF1213 PF06740.12 VBB35259.1 - 5.2 7.7 11.5 25 5.6 1.6 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1213) Tub_N PF16322.5 VBB35259.1 - 9.5 6.6 24.4 1.8 8.9 20.5 1.7 1 1 1 2 2 2 0 Tubby N-terminal ig PF00047.25 VBB35260.1 - 6.9e-11 42.2 0.0 0.00038 20.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 VBB35260.1 - 7.7e-08 32.3 0.1 0.0023 18.0 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB35260.1 - 2.4e-07 31.2 0.0 0.0023 18.5 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 VBB35260.1 - 0.00018 21.7 0.0 0.021 15.0 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 VBB35260.1 - 0.0077 16.5 0.0 2.4 8.6 0.0 2.2 1 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 VBB35260.1 - 0.0089 15.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain QVR PF17064.5 VBB35261.1 - 0.2 11.9 9.4 0.56 10.5 7.9 2.3 1 1 1 2 2 2 0 Sleepless protein DUF753 PF05444.12 VBB35261.1 - 1.6 8.7 9.8 0.29 11.1 3.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF753) Collagen PF01391.18 VBB35263.1 - 7.5e-11 41.6 37.0 4.7e-09 35.9 37.0 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 VBB35264.1 - 6.9e-31 107.6 0.0 7.5e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35264.1 - 1.1e-20 74.0 0.0 1.2e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 VBB35264.1 - 1.8e-05 23.7 0.0 2.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 VBB35264.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Fructosamin_kin PF03881.14 VBB35264.1 - 0.031 13.5 0.0 0.075 12.2 0.0 1.6 1 1 0 1 1 1 0 Fructosamine kinase APH PF01636.23 VBB35264.1 - 0.048 13.6 0.0 8.3 6.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 VBB35264.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Milton PF12448.8 VBB35267.1 - 0.00088 19.4 1.5 0.0014 18.8 1.5 1.5 1 1 0 1 1 1 1 Kinesin associated protein Tubulin PF00091.25 VBB35268.1 - 1.5e-05 25.3 0.0 1.6e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Histone PF00125.24 VBB35271.1 - 4e-17 62.8 2.7 4.7e-17 62.6 2.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 VBB35271.1 - 0.025 14.8 0.6 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 VBB35271.1 - 0.025 14.8 0.4 0.034 14.4 0.4 1.2 1 0 0 1 1 1 0 CENP-W protein WWE PF02825.20 VBB35271.1 - 0.18 12.4 1.6 7.1 7.3 1.5 2.6 2 1 0 2 2 2 0 WWE domain Spt20 PF12090.8 VBB35273.1 - 0.0023 17.6 6.2 0.0034 17.0 6.2 1.3 1 0 0 1 1 1 1 Spt20 family Androgen_recep PF02166.16 VBB35273.1 - 0.007 15.3 0.4 0.0074 15.2 0.4 1.2 1 0 0 1 1 1 1 Androgen receptor DUF2722 PF10846.8 VBB35273.1 - 0.013 14.4 13.5 0.067 12.1 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) WASH-7_C PF14746.6 VBB35273.1 - 0.037 13.7 2.2 0.053 13.2 2.2 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DUF4834 PF16118.5 VBB35273.1 - 0.061 14.3 3.2 0.12 13.3 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PepSY_TM PF03929.16 VBB35273.1 - 0.061 13.0 0.4 0.085 12.5 0.4 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF702 PF05142.12 VBB35273.1 - 0.12 12.8 5.1 0.21 12.0 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) EGF_CA PF07645.15 VBB35274.1 - 1.5e-16 60.3 36.7 4.5e-07 30.0 2.8 4.2 4 0 0 4 4 4 4 Calcium-binding EGF domain hEGF PF12661.7 VBB35274.1 - 1.9e-10 41.0 33.5 6.6e-06 26.6 1.4 5.6 6 1 0 6 6 6 3 Human growth factor-like EGF EGF_3 PF12947.7 VBB35274.1 - 2.3e-10 40.5 38.9 6.4e-05 23.1 7.7 4.6 4 1 1 5 5 5 3 EGF domain EGF PF00008.27 VBB35274.1 - 4.3e-10 39.7 34.2 8.1e-05 22.8 2.6 5.0 6 0 0 6 6 6 4 EGF-like domain Plasmod_Pvs28 PF06247.11 VBB35274.1 - 3.5e-09 36.8 26.0 3.8e-05 23.9 3.1 4.6 4 1 0 4 4 4 3 Pvs28 EGF domain FXa_inhibition PF14670.6 VBB35274.1 - 2.5e-05 24.4 29.0 0.013 15.7 1.9 4.4 3 1 1 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 VBB35274.1 - 0.00015 21.7 31.4 0.002 18.1 2.8 4.7 5 0 0 5 5 5 2 MSP1 EGF domain 1 cEGF PF12662.7 VBB35274.1 - 0.001 18.9 2.6 0.04 13.9 0.2 5.1 5 1 0 5 5 5 3 Complement Clr-like EGF-like S_locus_glycop PF00954.20 VBB35274.1 - 9.4 6.8 21.0 0.19 12.3 3.3 2.9 3 0 0 3 3 3 0 S-locus glycoprotein domain Collagen PF01391.18 VBB35275.1 - 7.4e-11 41.6 35.5 4.9e-10 39.0 35.5 1.9 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Kelch_1 PF01344.25 VBB35278.1 - 0.0028 17.2 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 VBB35278.1 - 0.057 13.4 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Collagen PF01391.18 VBB35279.1 - 1.4e-08 34.4 36.1 1.6e-08 34.2 36.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Rhabdo_ncap PF00945.18 VBB35280.1 - 9.3e-36 123.6 0.0 1.2e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein DUF2511 PF10709.9 VBB35280.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) Arrestin_N PF00339.29 VBB35281.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain zf-C2H2 PF00096.26 VBB35282.1 - 2.7e-11 43.3 11.5 0.0012 19.1 0.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB35282.1 - 1.4e-09 38.0 10.3 0.0039 17.9 0.2 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 VBB35282.1 - 0.00051 20.4 21.8 0.04 14.4 0.4 5.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 VBB35282.1 - 0.0036 17.3 1.2 0.11 12.6 0.2 3.7 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 VBB35282.1 - 0.025 14.9 8.8 0.032 14.6 0.3 3.1 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) SpoOE-like PF09388.10 VBB35282.1 - 0.056 13.3 1.1 7.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein zf-C2H2_3rep PF18868.1 VBB35282.1 - 0.13 13.0 8.3 6.1 7.5 0.5 2.9 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 VBB35282.1 - 0.13 11.9 0.3 4.8 6.9 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 VBB35282.1 - 0.22 11.3 6.3 1.4 8.7 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF4211 PF13926.6 VBB35282.1 - 0.3 11.1 4.1 0.84 9.7 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4211) zf-BED PF02892.15 VBB35282.1 - 0.63 10.1 5.0 0.31 11.1 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger C1_2 PF03107.16 VBB35282.1 - 1.1 9.6 4.4 19 5.7 0.1 3.1 2 1 1 3 3 3 0 C1 domain ASC PF00858.24 VBB35283.1 - 7e-15 54.9 0.3 7.8e-15 54.8 0.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Adaptin_N PF01602.20 VBB35284.1 - 1.2e-32 113.2 0.8 7.5e-17 61.1 0.1 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 VBB35284.1 - 1.1e-06 28.8 0.3 0.0041 17.2 0.1 2.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 B12D PF06522.11 VBB35284.1 - 0.042 13.6 0.9 12 5.8 0.0 2.7 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ScsC_N PF18312.1 VBB35284.1 - 0.053 13.3 0.1 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain EB PF01683.18 VBB35285.1 - 0.0031 17.8 2.7 0.0054 17.0 2.7 1.3 1 0 0 1 1 1 1 EB module Collagen PF01391.18 VBB35286.1 - 0.0001 21.9 11.9 0.0001 21.9 11.9 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) VASt PF16016.5 VBB35287.1 - 7.1e-24 85.0 1.1 8.1e-24 84.8 1.1 1.0 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain zf-C2H2_8 PF15909.5 VBB35287.1 - 0.08 13.2 0.2 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 C2H2-type zinc ribbon CDK5_activator PF03261.15 VBB35288.1 - 2.8e-68 231.1 0.2 3.4e-68 230.8 0.2 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein FGF PF00167.18 VBB35289.1 - 5.3e-17 62.1 0.0 2.6e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 Fibroblast growth factor DUF1962 PF09227.10 VBB35289.1 - 0.18 12.2 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Peptidase_M24 PF00557.24 VBB35291.1 - 1e-09 38.4 0.3 0.00021 21.0 0.1 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 CPSF100_C PF13299.6 VBB35296.1 - 3.5e-24 85.9 0.0 3.8e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Herpes_glycop_D PF01537.17 VBB35297.1 - 0.061 13.5 1.1 0.086 13.0 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain PLCC PF14466.6 VBB35298.1 - 0.0073 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 and C2-like Ca2+-binding lipoprotein Integrase_H2C2 PF17921.1 VBB35299.1 - 2e-07 31.0 0.4 4.8e-07 29.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 VBB35299.1 - 2.8e-05 24.3 0.0 0.0001 22.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 VBB35299.1 - 0.036 13.9 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain DSX_dimer PF08828.10 VBB35300.1 - 0.00016 21.3 6.9 7.1 6.4 0.3 5.2 1 1 4 5 5 5 4 Doublesex dimerisation domain V-ATPase_G_2 PF16999.5 VBB35300.1 - 0.61 10.5 19.0 0.88 10.0 8.5 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Borrelia_P83 PF05262.11 VBB35300.1 - 0.62 8.5 13.1 0.7 8.3 13.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein BAG6 PF12057.8 VBB35300.1 - 0.67 9.6 10.9 3.2 7.5 1.1 3.0 1 1 3 4 4 4 0 BCL2-associated athanogene 6 DUF930 PF06059.12 VBB35300.1 - 1.6 9.4 8.6 13 6.5 0.2 2.3 1 1 0 2 2 2 0 Domain of Unknown Function (DUF930) TSP_1 PF00090.19 VBB35301.1 - 1.5e-07 31.5 11.5 3e-06 27.3 7.4 3.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain Pkinase PF00069.25 VBB35302.1 - 5e-44 150.7 0.0 5.4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35302.1 - 1.1e-24 87.2 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 VBB35302.1 - 0.00014 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 VBB35302.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 VBB35302.1 - 0.026 14.4 0.1 0.039 13.9 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 VBB35302.1 - 0.028 13.4 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DB PF01682.19 VBB35304.1 - 4.2e-20 71.9 11.0 5.2e-20 71.6 11.0 1.0 1 0 0 1 1 1 1 DB module CENP-B_dimeris PF09026.10 VBB35305.1 - 0.36 11.2 17.9 0.43 11.0 17.9 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFAP1 PF06991.11 VBB35305.1 - 2 8.2 7.0 2.2 8.1 7.0 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing CDC45 PF02724.14 VBB35305.1 - 2.2 6.4 7.0 2.2 6.4 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 VBB35305.1 - 3.1 7.4 5.4 3.4 7.3 5.4 1.1 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 VBB35305.1 - 3.3 6.9 17.8 3.5 6.9 17.8 1.0 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 VBB35305.1 - 9.4 6.2 9.3 9.9 6.2 9.3 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Collagen PF01391.18 VBB35307.1 - 1.7e-18 66.1 65.0 2.4e-10 40.0 28.0 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.26 VBB35309.1 - 3e-10 40.0 18.3 0.00036 20.8 0.9 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB35309.1 - 4.2e-09 36.4 19.1 6.3e-06 26.4 1.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 VBB35309.1 - 5.8e-06 26.7 15.1 0.036 14.9 0.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Desulfoferrod_N PF06397.12 VBB35309.1 - 0.0047 16.5 0.7 0.59 9.8 0.1 2.3 2 0 0 2 2 2 1 Desulfoferrodoxin, N-terminal domain zf-C2H2_jaz PF12171.8 VBB35309.1 - 0.022 15.0 5.9 2.7 8.4 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PhnA_Zn_Ribbon PF08274.12 VBB35309.1 - 0.027 14.4 0.1 0.053 13.5 0.1 1.5 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-C2H2_6 PF13912.6 VBB35309.1 - 0.038 14.0 0.4 0.038 14.0 0.4 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger C1_2 PF03107.16 VBB35309.1 - 0.057 13.7 3.8 4.4 7.7 3.8 2.4 1 1 0 1 1 1 0 C1 domain CTU2 PF10288.9 VBB35309.1 - 0.058 13.6 2.1 0.31 11.3 2.1 1.9 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Elf1 PF05129.13 VBB35309.1 - 0.23 11.5 2.4 1 9.4 2.2 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf_UBZ PF18439.1 VBB35309.1 - 0.63 9.7 3.1 3.3 7.4 0.5 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 VBB35309.1 - 0.68 10.4 0.2 0.68 10.4 0.2 3.5 3 1 0 3 3 3 0 Zinc-finger of C2H2 type Ank_2 PF12796.7 VBB35311.1 - 6.3e-15 55.5 0.9 1.4e-07 32.0 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 VBB35311.1 - 1.4e-13 51.0 0.3 5.6e-10 39.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 VBB35311.1 - 4.7e-13 49.1 0.7 1.9e-08 34.4 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB35311.1 - 2.7e-11 42.6 0.8 0.00011 22.4 0.2 3.6 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 VBB35311.1 - 5.5e-10 39.2 1.3 2.2e-05 24.7 0.5 2.6 2 1 0 2 2 2 2 Ankyrin repeat SR1P PF13790.6 VBB35311.1 - 0.15 12.2 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 SR1 protein Laminin_EGF PF00053.24 VBB35314.1 - 1e-45 153.6 101.6 3.7e-10 39.8 15.4 6.2 6 0 0 6 6 6 6 Laminin EGF domain Trypsin PF00089.26 VBB35317.1 - 8.9e-17 61.6 0.0 2.2e-11 44.0 0.1 2.0 2 0 0 2 2 2 2 Trypsin DUF316 PF03761.15 VBB35317.1 - 6.9e-06 25.8 0.0 9.9e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 VBB35317.1 - 0.1 13.5 0.0 0.18 12.7 0.0 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain LIN52 PF10044.9 VBB35318.1 - 0.019 15.7 2.1 0.02 15.6 0.7 1.7 1 1 1 2 2 2 0 Retinal tissue protein DUF4105 PF13387.6 VBB35318.1 - 0.035 13.8 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Neur_chan_LBD PF02931.23 VBB35319.1 - 1.5e-25 89.9 0.3 1.7e-25 89.7 0.3 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain E_raikovi_mat PF06360.11 VBB35319.1 - 0.045 14.2 0.2 0.097 13.1 0.2 1.5 1 0 0 1 1 1 0 Euplotes raikovi mating pheromone Glyco_hydro_18 PF00704.28 VBB35320.1 - 4.5e-32 112.0 2.7 5.3e-32 111.8 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Actin PF00022.19 VBB35321.1 - 1.8e-122 408.9 0.0 6.2e-122 407.1 0.0 1.7 1 1 0 1 1 1 1 Actin DUF5641 PF18701.1 VBB35323.1 - 3.9e-06 26.9 1.1 7.1e-06 26.1 0.7 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 VBB35323.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 VBB35323.1 - 0.13 12.1 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain An_peroxidase PF03098.15 VBB35324.1 - 1.3e-59 202.2 0.0 1.4e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase adh_short PF00106.25 VBB35325.1 - 9.3e-20 70.9 0.0 1.1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB35325.1 - 2.1e-13 50.4 0.0 2.6e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 VBB35325.1 - 0.00073 19.5 0.0 0.00094 19.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 VBB35325.1 - 0.021 14.3 0.5 0.17 11.3 0.5 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sigma70_ner PF04546.13 VBB35325.1 - 0.039 13.8 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region adh_short PF00106.25 VBB35326.1 - 5.4e-11 42.3 0.0 6.4e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 VBB35326.1 - 1.6e-08 34.4 0.0 1.8e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SfsA PF03749.13 VBB35328.1 - 0.033 14.1 0.1 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain Halogen_Hydrol PF10112.9 VBB35328.1 - 0.097 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Auxin_canalis PF05703.11 VBB35328.1 - 0.2 11.5 0.9 0.26 11.2 0.9 1.1 1 0 0 1 1 1 0 Auxin canalisation Takusan PF04822.13 VBB35328.1 - 1.1 9.2 5.2 0.22 11.4 1.2 1.9 2 1 0 2 2 2 0 Takusan Pkinase PF00069.25 VBB35331.1 - 5.1e-07 29.3 0.1 6e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35331.1 - 0.0024 17.2 0.1 0.0031 16.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Collagen PF01391.18 VBB35332.1 - 2.8e-17 62.2 65.4 0.12 12.2 65.4 2.9 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) BrkDBD PF09607.10 VBB35333.1 - 1.2e-05 25.0 0.5 3.6e-05 23.5 0.5 1.8 1 1 0 1 1 1 1 Brinker DNA-binding domain CENP-B_N PF04218.13 VBB35333.1 - 3.5e-05 23.4 0.2 0.00011 21.8 0.2 1.7 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Glyco_transf_56 PF07429.11 VBB35335.1 - 0.021 14.0 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 DUF865 PF05906.11 VBB35336.1 - 0.1 12.4 0.8 0.21 11.4 0.8 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) p450 PF00067.22 VBB35337.1 - 8.9e-11 41.2 0.2 1.1e-10 40.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 VBB35338.1 - 5.1e-13 49.3 0.0 5.6e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 VBB35338.1 - 1.4e-06 27.8 0.0 1.4e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 VBB35338.1 - 0.0089 16.7 0.0 0.0094 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 VBB35338.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Nup153 PF08604.10 VBB35339.1 - 0.16 10.7 4.4 0.22 10.3 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like Dicty_CTDC PF00526.18 VBB35339.1 - 0.21 11.5 1.7 0.35 10.8 1.7 1.4 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat AMP-binding PF00501.28 VBB35341.1 - 3.8e-15 55.4 0.0 4.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Motile_Sperm PF00635.26 VBB35342.1 - 8.5e-15 54.5 0.0 9.4e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Astacin PF01400.24 VBB35343.1 - 2.3e-34 118.7 0.2 2.8e-32 111.9 0.2 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 VBB35343.1 - 0.014 15.0 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 VBB35343.1 - 0.04 12.9 0.1 0.062 12.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 VBB35343.1 - 0.057 13.6 1.9 0.073 13.2 1.9 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12 MtrB_PioB PF11854.8 VBB35343.1 - 0.067 11.5 0.1 0.067 11.5 0.1 1.0 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB Reprolysin_2 PF13574.6 VBB35343.1 - 0.15 11.9 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 VBB35343.1 - 0.16 11.8 2.1 0.23 11.3 2.0 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.8 VBB35343.1 - 0.18 11.4 2.7 0.28 10.8 2.7 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Sec34 PF04136.15 VBB35344.1 - 0.0038 17.1 0.8 0.0042 17.0 0.8 1.2 1 0 0 1 1 1 1 Sec34-like family APG17 PF04108.12 VBB35344.1 - 0.018 14.2 0.2 0.024 13.8 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Sigma70_ner PF04546.13 VBB35344.1 - 0.064 13.1 1.7 0.082 12.8 1.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region FapA PF03961.13 VBB35344.1 - 0.081 11.5 0.8 0.089 11.4 0.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A COMM_domain PF07258.14 VBB35344.1 - 0.37 10.9 2.3 0.35 11.0 0.5 1.9 2 0 0 2 2 2 0 COMM domain EGF PF00008.27 VBB35346.1 - 2.4e-32 110.9 58.4 1.7e-09 37.8 4.7 5.3 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 VBB35346.1 - 4e-16 59.0 60.3 3.8e-05 24.1 5.3 6.7 6 0 0 6 6 6 4 Human growth factor-like EGF EGF_CA PF07645.15 VBB35346.1 - 2.3e-11 43.7 62.3 0.00052 20.2 6.8 5.2 2 2 3 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 VBB35346.1 - 7.1e-09 35.7 49.8 0.0011 19.1 3.7 5.9 5 2 0 5 5 5 4 EGF domain EGF_2 PF07974.13 VBB35346.1 - 7.6e-09 35.8 69.5 7.3e-05 23.0 9.6 5.4 5 1 0 5 5 5 4 EGF-like domain FXa_inhibition PF14670.6 VBB35346.1 - 0.0056 16.9 60.2 0.073 13.4 9.6 5.9 2 1 3 5 5 5 4 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 VBB35346.1 - 0.095 12.9 58.0 1.9 8.7 10.9 5.1 1 1 4 5 5 5 0 Laminin EGF domain p450 PF00067.22 VBB35348.1 - 4.2e-58 197.2 0.3 4.9e-58 197.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 HGTP_anticodon PF03129.20 VBB35349.1 - 1.4e-16 60.4 0.3 1.6e-16 60.2 0.3 1.0 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 VBB35349.1 - 7.6e-11 42.0 0.5 7.7e-11 42.0 0.5 1.0 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs p450 PF00067.22 VBB35350.1 - 3.3e-33 115.2 0.1 3.7e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kunitz_BPTI PF00014.23 VBB35354.1 - 2.9e-37 126.7 25.6 4.2e-19 68.5 7.3 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Methyltransf_15 PF09445.10 VBB35354.1 - 0.03 13.9 0.2 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF4169 PF13770.6 VBB35354.1 - 0.091 13.1 0.4 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) PAN_2 PF08276.11 VBB35354.1 - 0.097 12.8 1.5 14 5.9 0.1 2.6 2 0 0 2 2 2 0 PAN-like domain Collagen PF01391.18 VBB35355.1 - 5.6e-12 45.2 33.6 2.6e-10 39.9 33.6 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB35356.1 - 2e-10 40.3 25.8 2.5e-10 40.0 25.8 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ephrin_rec_like PF07699.13 VBB35357.1 - 2.1e-27 94.6 33.0 7.8e-11 41.6 7.9 4.4 3 2 1 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 VBB35357.1 - 1.9e-07 30.9 22.1 0.067 13.2 3.3 5.1 1 1 4 6 6 6 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 VBB35357.1 - 0.0036 17.7 24.0 0.48 10.9 0.1 5.6 4 1 0 5 5 5 3 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 VBB35357.1 - 0.49 10.5 14.2 0.079 13.1 1.5 3.1 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) EGF_Tenascin PF18720.1 VBB35358.1 - 0.0023 17.9 8.3 0.023 14.7 1.9 2.3 2 0 0 2 2 2 2 Tenascin EGF domain FSA_C PF10479.9 VBB35358.1 - 0.029 12.5 4.4 0.032 12.4 4.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus EGF_2 PF07974.13 VBB35358.1 - 0.043 14.2 10.7 1.2 9.5 1.0 2.3 2 0 0 2 2 2 0 EGF-like domain HupE_UreJ_2 PF13795.6 VBB35358.1 - 0.062 13.0 1.5 0.081 12.6 1.5 1.2 1 0 0 1 1 1 0 HupE / UreJ protein bZIP_C PF12498.8 VBB35358.1 - 0.11 13.5 0.7 0.16 12.9 0.7 1.2 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Laminin_EGF PF00053.24 VBB35358.1 - 0.26 11.4 5.7 5.1 7.3 1.7 2.3 1 1 1 2 2 2 0 Laminin EGF domain EGF PF00008.27 VBB35358.1 - 2 8.8 10.2 1.4 9.3 2.6 2.7 3 0 0 3 3 3 0 EGF-like domain Guanylate_cyc PF00211.20 VBB35359.1 - 1.7e-54 184.2 0.5 2.2e-54 183.9 0.5 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UBA PF00627.31 VBB35360.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.3 3 0 0 3 3 3 0 UBA/TS-N domain TSC22 PF01166.18 VBB35361.1 - 0.043 14.1 1.8 0.071 13.4 1.8 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family LisH PF08513.11 VBB35361.1 - 0.087 12.8 0.2 0.24 11.4 0.2 1.8 1 0 0 1 1 1 0 LisH PRD PF00874.20 VBB35361.1 - 0.15 12.3 4.2 0.76 10.1 0.3 2.2 2 0 0 2 2 2 0 PRD domain Holin_BhlA PF10960.8 VBB35361.1 - 0.15 12.0 3.7 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 BhlA holin family TFR_dimer PF04253.15 VBB35362.1 - 7e-20 71.3 0.0 8.8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Myosin_head PF00063.21 VBB35363.1 - 5.3e-14 51.4 0.0 5.9e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Methyltransf_23 PF13489.6 VBB35364.1 - 0.034 14.0 0.9 0.034 14.0 0.9 1.1 1 0 0 1 1 1 0 Methyltransferase domain ANAPC_CDC26 PF10471.9 VBB35364.1 - 0.1 13.5 15.6 0.12 13.3 15.6 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 VBB35364.1 - 0.2 11.2 20.4 0.2 11.2 20.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 VBB35364.1 - 0.33 9.9 16.4 0.31 9.9 16.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.10 VBB35364.1 - 1.6 7.3 17.2 1.5 7.4 17.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.6 VBB35364.1 - 2.1 7.6 7.8 2.2 7.5 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 VBB35364.1 - 5.1 7.0 18.9 4.8 7.1 18.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 VBB35364.1 - 6.1 5.5 6.0 5.5 5.6 6.0 1.0 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 VBB35364.1 - 6.6 5.4 18.0 6.5 5.5 18.0 1.1 1 0 0 1 1 1 0 Androgen receptor XG_FTase PF03254.13 VBB35365.1 - 0.026 13.2 0.0 0.026 13.1 0.0 1.0 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Motile_Sperm PF00635.26 VBB35366.1 - 6.6e-23 80.6 0.0 7.5e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Zona_pellucida PF00100.23 VBB35367.1 - 0.021 14.6 0.0 0.024 14.5 0.0 1.0 1 0 0 1 1 1 0 Zona pellucida-like domain Zip PF02535.22 VBB35369.1 - 5.8e-42 144.1 13.9 6.3e-42 144.0 13.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MpPF26 PF07666.11 VBB35369.1 - 0.019 15.0 1.8 0.019 15.0 1.8 1.9 2 0 0 2 2 2 0 M penetrans paralogue family 26 Cytochrome-c551 PF10643.9 VBB35369.1 - 0.98 9.0 4.5 0.74 9.4 1.3 1.8 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Phage_holin_5_2 PF16079.5 VBB35369.1 - 1.3 9.4 7.2 2.3 8.6 0.0 3.3 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V HYR PF02494.16 VBB35373.1 - 6.9e-23 80.8 6.6 1.1e-12 48.1 1.2 2.5 2 1 0 2 2 2 2 HYR domain Pkinase PF00069.25 VBB35374.1 - 2.8e-41 141.7 0.1 3.1e-41 141.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 VBB35374.1 - 4.7e-22 78.5 0.1 5e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 VBB35374.1 - 0.012 15.0 0.4 0.017 14.5 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 VBB35374.1 - 0.018 14.4 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 VBB35374.1 - 0.07 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 VBB35375.1 - 4.7e-12 45.8 0.3 7.5e-12 45.2 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB35375.1 - 0.0071 16.5 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Collagen PF01391.18 VBB35377.1 - 1e-08 34.8 46.2 3e-06 26.9 46.2 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB35378.1 - 2.5e-14 52.7 73.1 7.6e-09 35.2 29.3 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CUT PF02376.15 VBB35379.1 - 1.9e-33 114.4 0.3 2.2e-33 114.2 0.3 1.0 1 0 0 1 1 1 1 CUT domain Forkhead PF00250.18 VBB35380.1 - 5.2e-15 55.5 0.1 5.2e-15 55.5 0.1 1.8 2 1 0 2 2 2 1 Forkhead domain ERM PF00769.19 VBB35381.1 - 0.0088 15.9 2.5 0.012 15.5 2.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Mobilization_B PF17511.2 VBB35381.1 - 0.082 13.3 0.3 0.082 13.3 0.3 1.5 2 0 0 2 2 2 0 Mobilization protein B DUF2110 PF09883.9 VBB35381.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) PRP1_N PF06424.12 VBB35381.1 - 0.11 12.9 2.3 0.25 11.7 2.2 1.7 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal MFP2b PF12150.8 VBB35382.1 - 2.1e-39 135.8 0.0 2.3e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Cytosolic motility protein PnpCD_PnpD_N PF18191.1 VBB35382.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal STAT_alpha PF01017.20 VBB35385.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 STAT protein, all-alpha domain Codanin-1_C PF15296.6 VBB35385.1 - 0.018 15.1 0.1 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Codanin-1 C-terminus ASC PF00858.24 VBB35391.1 - 6.7e-17 61.6 5.1 7.5e-17 61.4 5.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4685 PF15737.5 VBB35391.1 - 0.016 15.7 0.1 0.03 14.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4685) PDE4_UCR PF18100.1 VBB35392.1 - 3.8e-10 40.4 0.1 6.5e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) DUF4497 PF14924.6 VBB35393.1 - 0.035 14.6 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Shadoo PF14999.6 VBB35393.1 - 0.12 12.4 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective zf-H2C2_5 PF13909.6 VBB35394.1 - 0.021 14.5 0.3 0.041 13.6 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 VBB35394.1 - 0.03 14.7 0.5 0.062 13.8 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger double domain Peptidase_A17 PF05380.13 VBB35395.1 - 1.8e-05 24.8 1.6 3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Pao retrotransposon peptidase Collagen PF01391.18 VBB35396.1 - 4.8e-05 23.0 14.1 5.9e-05 22.7 14.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CAP PF00188.26 VBB35397.1 - 1.2e-05 26.2 0.1 1.2e-05 26.1 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_C1 PF00112.23 VBB35398.1 - 1.1e-30 107.3 0.0 1.3e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Caskin1-CID PF16600.5 VBB35399.1 - 0.27 11.8 5.3 0.26 11.9 1.7 2.4 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Motile_Sperm PF00635.26 VBB35403.1 - 8.5e-15 54.5 0.0 9.4e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SpoIIP PF07454.11 VBB35405.1 - 0.0021 17.6 13.5 0.0022 17.5 13.5 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 VBB35405.1 - 0.0031 16.6 16.7 0.0032 16.5 16.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CobT PF06213.12 VBB35405.1 - 0.0038 16.7 19.9 0.0041 16.5 19.9 1.0 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 VBB35405.1 - 0.004 17.3 9.2 0.0043 17.3 9.2 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 VBB35405.1 - 0.0045 17.0 38.3 0.0048 16.9 38.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 VBB35405.1 - 0.005 16.5 7.1 0.0061 16.2 7.1 1.2 1 0 0 1 1 1 1 FAM176 family PepSY_TM PF03929.16 VBB35405.1 - 0.0083 15.8 7.3 0.0094 15.6 7.3 1.1 1 0 0 1 1 1 1 PepSY-associated TM region Connexin PF00029.19 VBB35405.1 - 0.0084 15.9 7.8 0.0085 15.9 7.8 1.1 1 0 0 1 1 1 1 Connexin RR_TM4-6 PF06459.12 VBB35405.1 - 0.0088 15.9 12.9 0.0092 15.8 12.9 1.0 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 VBB35405.1 - 0.0091 15.4 11.7 0.011 15.1 11.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) EPL1 PF10513.9 VBB35405.1 - 0.0095 16.3 16.4 0.012 16.0 16.4 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like eIF3_subunit PF08597.10 VBB35405.1 - 0.0096 15.9 9.4 0.0099 15.8 9.4 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4770 PF15994.5 VBB35405.1 - 0.011 16.0 14.2 0.013 15.7 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DDHD PF02862.17 VBB35405.1 - 0.011 15.9 10.5 0.011 16.0 10.5 1.1 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 VBB35405.1 - 0.012 13.6 13.9 0.012 13.6 13.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 VBB35405.1 - 0.013 13.6 12.1 0.015 13.5 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ASC PF00858.24 VBB35405.1 - 0.013 14.5 8.9 0.017 14.1 8.9 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF3464 PF11947.8 VBB35405.1 - 0.014 15.1 12.8 0.018 14.8 12.8 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CCDC53 PF10152.9 VBB35405.1 - 0.015 15.7 14.3 0.017 15.6 14.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex MecA PF05389.12 VBB35405.1 - 0.016 14.9 8.3 0.019 14.6 8.3 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Pex14_N PF04695.13 VBB35405.1 - 0.017 15.8 26.5 0.018 15.7 26.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FmiP_Thoc5 PF09766.9 VBB35405.1 - 0.018 14.4 17.7 0.018 14.3 17.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 O-antigen_lig PF13425.6 VBB35405.1 - 0.022 13.6 7.4 0.025 13.4 7.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Presenilin PF01080.17 VBB35405.1 - 0.023 13.5 18.0 0.026 13.3 18.0 1.0 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 VBB35405.1 - 0.024 12.9 27.0 0.025 12.9 27.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BORG_CEP PF14957.6 VBB35405.1 - 0.026 15.7 12.3 0.032 15.4 12.3 1.1 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 VBB35405.1 - 0.026 13.3 14.8 0.03 13.1 14.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5385 PF17359.2 VBB35405.1 - 0.026 14.1 13.7 0.034 13.7 13.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) EIIBC-GUT_N PF03612.14 VBB35405.1 - 0.027 14.2 13.0 0.037 13.8 13.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MPM1 PF17234.2 VBB35405.1 - 0.042 14.1 16.6 0.062 13.6 16.6 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 CLN3 PF02487.17 VBB35405.1 - 0.044 12.8 11.5 0.048 12.7 11.5 1.1 1 0 0 1 1 1 0 CLN3 protein Spem1 PF15670.5 VBB35405.1 - 0.047 13.3 12.7 0.051 13.2 12.7 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF3408 PF11888.8 VBB35405.1 - 0.049 13.8 13.3 0.066 13.4 13.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF3292 PF11696.8 VBB35405.1 - 0.062 11.7 8.7 0.063 11.7 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF3295 PF11702.8 VBB35405.1 - 0.064 12.6 18.7 0.068 12.5 18.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ALMT PF11744.8 VBB35405.1 - 0.065 12.1 11.4 0.065 12.0 11.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 VBB35405.1 - 0.067 12.2 14.0 0.067 12.2 14.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MMR1 PF08505.10 VBB35405.1 - 0.079 13.2 18.8 0.096 13.0 18.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UPF0560 PF10577.9 VBB35405.1 - 0.087 11.3 23.7 0.097 11.2 23.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Endostatin PF06482.11 VBB35405.1 - 0.091 12.2 15.8 0.099 12.1 15.8 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin G0-G1_switch_2 PF15103.6 VBB35405.1 - 0.099 13.1 11.4 0.16 12.4 11.4 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 CCSAP PF15748.5 VBB35405.1 - 0.11 12.7 18.7 0.12 12.5 18.7 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ARL6IP6 PF15062.6 VBB35405.1 - 0.11 12.6 0.9 0.11 12.6 0.9 2.4 1 1 1 2 2 1 0 Haemopoietic lineage transmembrane helix Folate_carrier PF01770.18 VBB35405.1 - 0.11 11.2 7.9 0.12 11.1 7.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier Med15 PF09606.10 VBB35405.1 - 0.11 11.1 37.4 0.15 10.7 37.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.6 VBB35405.1 - 0.11 12.4 12.3 0.13 12.2 12.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF5523 PF17661.1 VBB35405.1 - 0.12 12.1 18.1 0.15 11.7 18.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CSG2 PF16965.5 VBB35405.1 - 0.12 11.3 8.0 0.13 11.2 8.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DREPP PF05558.12 VBB35405.1 - 0.13 12.2 1.5 0.15 11.9 1.5 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Velvet PF11754.8 VBB35405.1 - 0.13 12.1 15.6 0.15 12.0 15.6 1.1 1 0 0 1 1 1 0 Velvet factor dsRBD2 PF17842.1 VBB35405.1 - 0.13 12.4 11.3 0.18 12.0 11.3 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 RPN2_C PF18004.1 VBB35405.1 - 0.15 11.9 16.0 0.22 11.5 16.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tho2 PF11262.8 VBB35405.1 - 0.16 11.2 10.8 0.18 11.0 10.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AIF_C PF14721.6 VBB35405.1 - 0.16 12.3 10.7 0.21 11.9 10.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Usp PF00582.26 VBB35405.1 - 0.16 12.5 1.1 0.23 12.0 1.1 1.3 1 0 0 1 1 1 0 Universal stress protein family PA26 PF04636.13 VBB35405.1 - 0.16 10.8 10.0 0.18 10.7 10.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF913 PF06025.12 VBB35405.1 - 0.17 10.9 10.7 0.16 10.9 10.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4228 PF14009.6 VBB35405.1 - 0.19 12.1 6.7 0.18 12.2 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TERB2 PF15101.6 VBB35405.1 - 0.19 11.7 21.8 0.24 11.4 21.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cellulose_synt PF03552.14 VBB35405.1 - 0.2 10.1 5.2 0.21 10.1 5.2 1.0 1 0 0 1 1 1 0 Cellulose synthase SID-1_RNA_chan PF13965.6 VBB35405.1 - 0.22 9.9 9.2 0.23 9.8 9.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FYDLN_acid PF09538.10 VBB35405.1 - 0.22 12.2 7.8 0.29 11.8 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) OATP PF03137.20 VBB35405.1 - 0.23 9.7 6.5 0.24 9.7 6.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pal1 PF08316.11 VBB35405.1 - 0.26 12.1 6.8 0.31 11.8 6.8 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein NEMP PF10225.9 VBB35405.1 - 0.28 10.8 7.5 0.32 10.6 7.5 1.1 1 0 0 1 1 1 0 NEMP family Suf PF05843.14 VBB35405.1 - 0.32 11.0 20.8 0.45 10.4 20.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NPR3 PF03666.13 VBB35405.1 - 0.32 9.7 14.1 0.36 9.6 14.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3391 PF11871.8 VBB35405.1 - 0.33 11.5 15.5 0.39 11.2 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) EFTUD2 PF16004.5 VBB35405.1 - 0.33 11.6 20.6 0.43 11.2 20.6 1.1 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Scs3p PF10261.9 VBB35405.1 - 0.35 10.3 3.1 0.38 10.2 3.1 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM REC114-like PF15165.6 VBB35405.1 - 0.39 10.5 19.0 0.41 10.4 19.0 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Hydin_ADK PF17213.3 VBB35405.1 - 0.4 10.9 11.7 0.51 10.6 11.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AUX_IAA PF02309.16 VBB35405.1 - 0.41 10.4 10.6 0.48 10.2 10.6 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF1387 PF07139.11 VBB35405.1 - 0.43 10.3 16.7 0.44 10.2 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GREB1 PF15782.5 VBB35405.1 - 0.43 7.6 18.2 0.45 7.6 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DcuA_DcuB PF03605.14 VBB35405.1 - 0.44 9.4 2.9 0.47 9.3 2.9 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Peptidase_S64 PF08192.11 VBB35405.1 - 0.45 8.9 16.2 0.48 8.8 16.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.16 VBB35405.1 - 0.46 10.5 12.0 0.46 10.5 12.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 VBB35405.1 - 0.49 9.8 11.9 0.56 9.6 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EOS1 PF12326.8 VBB35405.1 - 0.53 10.2 7.9 0.62 10.0 7.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Lin-8 PF03353.15 VBB35405.1 - 0.55 9.7 22.7 0.62 9.6 22.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HSP90 PF00183.18 VBB35405.1 - 0.56 9.0 13.2 0.69 8.7 13.2 1.0 1 0 0 1 1 1 0 Hsp90 protein PTPRCAP PF15713.5 VBB35405.1 - 0.59 10.4 18.3 0.71 10.2 18.3 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated YfhO PF09586.10 VBB35405.1 - 0.61 8.2 7.5 0.68 8.1 7.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Membralin PF09746.9 VBB35405.1 - 0.62 9.0 10.0 0.65 9.0 10.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Band_3_cyto PF07565.13 VBB35405.1 - 0.63 9.8 15.9 0.74 9.6 15.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.13 VBB35405.1 - 0.65 8.9 20.3 0.75 8.7 20.3 1.0 1 0 0 1 1 1 0 Paf1 YABBY PF04690.13 VBB35405.1 - 0.66 10.5 12.7 0.75 10.3 12.7 1.2 1 0 0 1 1 1 0 YABBY protein MCD PF05292.11 VBB35405.1 - 0.74 9.3 8.9 0.91 9.0 8.9 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF2126 PF09899.9 VBB35405.1 - 0.76 7.8 11.8 0.82 7.7 11.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PPL5 PF18168.1 VBB35405.1 - 0.83 8.9 10.5 0.93 8.7 10.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CBP_BcsG PF11658.8 VBB35405.1 - 0.85 7.9 12.1 0.93 7.8 12.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pap_E4 PF02711.14 VBB35405.1 - 0.91 10.5 16.5 1.2 10.2 16.5 1.2 1 0 0 1 1 1 0 E4 protein Hid1 PF12722.7 VBB35405.1 - 0.91 7.6 16.7 0.97 7.5 16.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4638 PF15472.6 VBB35405.1 - 1 9.1 13.9 1.2 8.9 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Ndc1_Nup PF09531.10 VBB35405.1 - 1.1 7.9 14.6 1.2 7.8 14.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gti1_Pac2 PF09729.9 VBB35405.1 - 1.1 9.3 16.3 1.4 9.0 16.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Baculo_PP31 PF05311.11 VBB35405.1 - 1.2 8.6 15.4 1.4 8.4 15.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDC45 PF02724.14 VBB35405.1 - 1.2 7.3 14.8 1.4 7.1 14.8 1.0 1 0 0 1 1 1 0 CDC45-like protein ATAD4 PF15321.6 VBB35405.1 - 1.2 10.5 11.7 2 9.8 11.7 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 FAM91_C PF14648.6 VBB35405.1 - 1.3 7.8 10.1 1.5 7.6 10.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus 5_nucleotid PF05761.14 VBB35405.1 - 1.3 7.8 10.5 1.4 7.7 10.5 1.0 1 0 0 1 1 1 0 5' nucleotidase family RICTOR_N PF14664.6 VBB35405.1 - 1.4 7.8 7.9 1.7 7.5 7.9 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF1980 PF09323.10 VBB35405.1 - 1.6 8.6 14.2 1.9 8.4 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Radical_SAM_N PF08497.10 VBB35405.1 - 1.6 7.9 8.9 1.7 7.8 8.9 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal DUF5524 PF17662.1 VBB35405.1 - 1.6 8.0 12.6 1.8 7.9 12.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5524) Nucleoside_tran PF01733.18 VBB35405.1 - 1.7 7.9 5.2 1.7 7.9 5.2 1.1 1 0 0 1 1 1 0 Nucleoside transporter TMEM51 PF15345.6 VBB35405.1 - 1.9 8.3 20.9 3 7.6 20.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Paramyxo_ncap PF00973.19 VBB35405.1 - 2.1 7.1 11.6 2.2 7.1 11.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NARP1 PF12569.8 VBB35405.1 - 2.2 7.1 15.7 2.6 6.9 15.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Plasmodium_Vir PF05795.11 VBB35405.1 - 2.3 7.6 11.5 2.5 7.5 11.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ureide_permease PF07168.11 VBB35405.1 - 2.4 6.8 8.4 2.8 6.6 8.4 1.1 1 0 0 1 1 1 0 Ureide permease Pannexin_like PF12534.8 VBB35405.1 - 2.5 7.1 15.9 3.1 6.8 15.9 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 PIP5K PF01504.18 VBB35405.1 - 2.9 7.1 16.1 3.4 6.8 16.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Otopetrin PF03189.13 VBB35405.1 - 2.9 6.6 11.1 3 6.6 11.1 1.0 1 0 0 1 1 1 0 Otopetrin Zip PF02535.22 VBB35405.1 - 3.3 6.8 9.6 3.7 6.7 9.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HCO3_cotransp PF00955.21 VBB35405.1 - 3.4 6.4 8.3 3.6 6.3 8.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family Peptidase_M56 PF05569.11 VBB35405.1 - 3.6 6.7 7.4 4.6 6.4 7.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1764 PF08576.10 VBB35405.1 - 3.7 8.5 16.0 5.6 7.9 16.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DNApol_Exo PF18136.1 VBB35405.1 - 3.7 6.6 14.3 4.3 6.4 14.3 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Serinc PF03348.15 VBB35405.1 - 3.8 6.3 13.8 4.5 6.1 13.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Sec62 PF03839.16 VBB35405.1 - 4 6.9 14.1 4.8 6.6 14.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Sin_N PF04801.13 VBB35405.1 - 4 6.5 28.0 4.6 6.3 28.0 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region GOLD_2 PF13897.6 VBB35405.1 - 4.6 7.7 7.6 6 7.4 7.6 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FliP PF00813.20 VBB35405.1 - 4.7 7.0 7.8 5.2 6.9 7.8 1.1 1 0 0 1 1 1 0 FliP family Endonuc_Holl PF10107.9 VBB35405.1 - 5.3 6.9 12.6 6.5 6.6 12.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase FPN1 PF06963.12 VBB35405.1 - 5.8 5.3 7.6 6.5 5.2 7.6 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4192 PF13830.6 VBB35405.1 - 6.1 6.8 5.5 6.9 6.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) MDM10 PF12519.8 VBB35405.1 - 7.9 5.2 17.0 8.9 5.0 17.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DDRGK PF09756.9 VBB35405.1 - 8.6 5.9 25.8 11 5.6 25.8 1.1 1 0 0 1 1 1 0 DDRGK domain MMU163 PF17119.5 VBB35405.1 - 9.3 5.3 10.3 12 5.0 10.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis MAJIN PF15077.6 VBB35405.1 - 9.5 5.9 13.9 11 5.8 13.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein HGTP_anticodon2 PF12745.7 VBB35405.1 - 9.6 5.6 18.8 14 5.1 18.8 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs HCO3_cotransp PF00955.21 VBB35407.1 - 2.3e-33 115.8 7.9 1e-19 70.8 2.4 2.0 1 1 1 2 2 2 2 HCO3- transporter family Integrase_H2C2 PF17921.1 VBB35409.1 - 2.6e-12 46.6 0.3 5.7e-12 45.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 VBB35409.1 - 1.4e-10 41.4 0.0 3.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 VBB35409.1 - 0.0093 16.2 0.6 0.02 15.1 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 VBB35409.1 - 0.027 14.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Rsm1 PF08600.10 VBB35412.1 - 0.14 12.3 0.2 0.22 11.7 0.0 1.4 1 1 1 2 2 2 0 Rsm1-like SfsA PF03749.13 VBB35413.1 - 0.032 14.1 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain Halogen_Hydrol PF10112.9 VBB35413.1 - 0.086 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Auxin_canalis PF05703.11 VBB35413.1 - 0.23 11.4 1.1 0.3 11.0 1.1 1.1 1 0 0 1 1 1 0 Auxin canalisation Takusan PF04822.13 VBB35413.1 - 1 9.3 5.2 0.22 11.4 1.2 1.9 2 1 0 2 2 2 0 Takusan Thioredoxin_13 PF18401.1 VBB35414.1 - 0.03 14.2 0.0 0.039 13.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Spore_GerAC PF05504.11 VBB35414.1 - 0.073 13.3 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal TTR-52 PF01060.23 VBB35415.1 - 8.7e-05 23.2 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 Transthyretin-like family TQ PF18202.1 VBB35415.1 - 0.18 12.3 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 T-Q ester bond containing domain DUF4946 PF16304.5 VBB35417.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) TTR-52 PF01060.23 VBB35418.1 - 0.01 16.5 0.0 0.013 16.2 0.0 1.2 1 0 0 1 1 1 0 Transthyretin-like family HTH_psq PF05225.16 VBB35422.1 - 1.8e-05 24.4 0.0 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF3621 PF12285.8 VBB35422.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) DUF4741 PF15897.5 VBB35422.1 - 0.19 11.5 2.2 0.79 9.5 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4741) FIVAR PF07554.13 VBB35422.1 - 1.9 9.3 6.1 3.6 8.4 1.4 2.6 3 0 0 3 3 3 0 FIVAR domain C2 PF00168.30 VBB35423.1 - 4.5e-11 43.0 0.1 1.6e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 C2 domain F-box PF00646.33 VBB35424.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 VBB35424.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 F-box-like Aa_trans PF01490.18 VBB35426.1 - 1.4e-13 50.4 21.8 1.5e-09 37.1 1.7 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein ERGIC_N PF13850.6 VBB35426.1 - 0.016 15.5 0.0 0.016 15.5 0.0 2.8 1 1 2 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ABC2_membrane_2 PF12679.7 VBB35426.1 - 2.7 7.2 13.8 3.9 6.7 13.9 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein UPF0242 PF06785.11 VBB35426.1 - 4.2 7.4 6.6 0.87 9.7 1.9 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SLC12 PF03522.15 VBB35427.1 - 2.4e-56 191.6 0.0 2.7e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Solute carrier family 12 ELFV_dehydrog_N PF02812.18 VBB35428.1 - 9.1e-31 106.4 0.1 1.3e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 VBB35428.1 - 2.6e-15 56.8 0.7 3.7e-15 56.3 0.7 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF948 PF06103.11 VBB35430.1 - 0.055 13.7 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ANAPC4 PF12896.7 VBB35430.1 - 0.079 12.4 0.1 0.079 12.4 0.1 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 SlyX PF04102.12 VBB35430.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 1 1 2 2 2 0 SlyX FLYWCH PF04500.16 VBB35431.1 - 0.002 18.2 2.1 0.0034 17.5 2.1 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain zf-GRF PF06839.12 VBB35431.1 - 0.034 14.3 0.3 0.062 13.4 0.3 1.4 1 0 0 1 1 1 0 GRF zinc finger Cyt-b5 PF00173.28 VBB35432.1 - 9.2e-05 22.5 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LPAM_1 PF08139.12 VBB35433.1 - 0.87 10.2 2.9 3.5 8.3 2.9 2.1 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF1759 PF03564.15 VBB35434.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) ASC PF00858.24 VBB35436.1 - 1.2e-14 54.1 0.4 1.3e-14 54.0 0.4 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Collagen PF01391.18 VBB35437.1 - 2.6e-11 43.1 25.2 3.3e-11 42.8 25.2 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M24 PF00557.24 VBB35438.1 - 1.1e-18 67.7 0.0 1.3e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 ASC PF00858.24 VBB35440.1 - 7.4e-15 54.9 6.9 8.3e-15 54.7 6.9 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UPF0122 PF04297.14 VBB35440.1 - 0.019 15.2 1.5 0.71 10.2 0.5 2.4 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like DUF4685 PF15737.5 VBB35440.1 - 0.029 14.8 0.1 0.046 14.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4685) Rhabdo_ncap PF00945.18 VBB35441.1 - 1.2e-34 119.9 0.0 2.9e-34 118.7 0.0 1.6 2 0 0 2 2 2 1 Rhabdovirus nucleocapsid protein ARD PF03079.14 VBB35442.1 - 5.9e-08 33.1 0.1 6.6e-08 32.9 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Ank_4 PF13637.6 VBB35443.1 - 5.4e-09 36.4 0.4 3.1e-07 30.8 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB35443.1 - 3.3e-08 34.0 0.0 8.9e-07 29.4 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 VBB35443.1 - 5.1e-07 29.5 0.2 0.12 13.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 VBB35443.1 - 8.7e-06 25.9 0.1 0.099 13.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 VBB35443.1 - 0.00017 21.8 0.1 0.19 12.2 0.1 3.4 4 1 0 4 4 4 1 Ankyrin repeat FTH PF01827.27 VBB35443.1 - 0.094 12.5 0.3 0.094 12.5 0.3 1.7 2 0 0 2 2 2 0 FTH domain rve PF00665.26 VBB35445.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 VBB35445.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Patched PF02460.18 VBB35447.1 - 4.4e-10 38.3 6.5 5.3e-10 38.1 6.5 1.0 1 0 0 1 1 1 1 Patched family Myco_arth_vir_N PF09610.10 VBB35447.1 - 1.4 9.0 6.2 3 8.0 0.2 2.7 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) p450 PF00067.22 VBB35448.1 - 9.9e-41 139.9 0.0 1.2e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rap_GAP PF02145.15 VBB35450.1 - 6.8e-45 152.9 0.1 7.8e-45 152.7 0.1 1.0 1 0 0 1 1 1 1 Rap/ran-GAP MtrF PF09472.10 VBB35450.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Collagen PF01391.18 VBB35452.1 - 7.2e-11 41.7 24.7 2.1e-10 40.2 24.7 1.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_18 PF00704.28 VBB35454.1 - 1.5e-18 67.6 0.2 1.7e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Orthopox_B11R PF07033.11 VBB35455.1 - 0.0075 16.0 0.3 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 Orthopoxvirus B11R protein SLD5_C PF16922.5 VBB35457.1 - 0.0062 16.7 0.1 0.0077 16.4 0.1 1.2 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus R3H PF01424.22 VBB35458.1 - 0.035 14.1 0.1 0.095 12.7 0.1 1.8 1 1 0 1 1 1 0 R3H domain Peptidase_A17 PF05380.13 VBB35459.1 - 2.9e-36 124.9 0.0 4.3e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase Dicty_REP PF05086.12 VBB35460.1 - 0.011 13.8 14.6 0.013 13.5 14.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_L28e PF01778.17 VBB35460.1 - 0.27 12.0 7.2 0.048 14.4 2.5 2.2 2 1 0 2 2 2 0 Ribosomal L28e protein family Kringle PF00051.18 VBB35460.1 - 5 7.5 11.6 2.7 8.4 1.1 2.8 1 1 2 3 3 3 0 Kringle domain PBP1_TM PF14812.6 VBB35460.1 - 9.8 6.6 9.9 1.2 9.5 4.1 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 VBB35461.1 - 4.1e-20 72.3 6.6 4.6e-20 72.1 6.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MpPF26 PF07666.11 VBB35461.1 - 0.0059 16.7 2.1 0.0082 16.3 2.1 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 26 Phage_holin_5_2 PF16079.5 VBB35461.1 - 0.27 11.6 2.9 1.2 9.5 0.1 2.3 1 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Cytochrome-c551 PF10643.9 VBB35461.1 - 0.29 10.7 4.2 1 8.9 4.0 1.7 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Moulting_cycle PF04870.16 VBB35463.1 - 2.6e-59 201.3 1.4 6.6e-59 199.9 1.4 1.6 1 1 0 1 1 1 1 Moulting cycle Collagen PF01391.18 VBB35464.1 - 5.7e-13 48.4 37.1 1.6e-09 37.4 37.1 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_C1 PF00112.23 VBB35465.1 - 1.8e-32 113.2 0.0 2e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Tombus_P19 PF03220.13 VBB35466.1 - 0.0036 17.0 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Tombusvirus P19 core protein Capsid_N PF16903.5 VBB35466.1 - 0.04 13.5 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 Major capsid protein N-terminus DUF5641 PF18701.1 VBB35469.1 - 1.3e-21 76.6 0.1 2.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) rve PF00665.26 VBB35469.1 - 0.0035 17.5 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain PH PF00169.29 VBB35470.1 - 3.9e-06 27.3 0.0 5.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 PH domain TF_AP-2 PF03299.14 VBB35471.1 - 1.1e-21 77.8 0.2 1.2e-21 77.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 SNAD1 PF18744.1 VBB35471.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 AMP-binding PF00501.28 VBB35473.1 - 2.2e-32 112.2 0.2 2.6e-32 112.0 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AbiJ_NTD4 PF18863.1 VBB35474.1 - 0.038 14.4 0.0 0.038 14.4 0.0 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 DUF4404 PF14357.6 VBB35474.1 - 0.11 13.1 0.0 0.18 12.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Peptidase_A17 PF05380.13 VBB35475.1 - 2.7e-20 73.0 0.1 4.1e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 VBB35475.1 - 7.9e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spectrin PF00435.21 VBB35476.1 - 0.024 15.1 0.1 0.025 15.1 0.1 1.0 1 0 0 1 1 1 0 Spectrin repeat CRF PF00473.17 VBB35477.1 - 0.035 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor family Integrase_H2C2 PF17921.1 VBB35486.1 - 4.4e-12 45.9 1.8 9e-12 44.9 1.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 VBB35486.1 - 0.0034 17.6 0.1 0.01 16.0 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DNApol_Exo PF18136.1 VBB35488.1 - 1.3e-46 159.0 0.0 1.5e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain Integrase_H2C2 PF17921.1 VBB35493.1 - 1.4e-06 28.3 0.4 2.6e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain AMP-binding PF00501.28 VBB35494.1 - 1.7e-21 76.3 0.0 2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Collagen PF01391.18 VBB35496.1 - 3.9e-11 42.5 29.5 6.9e-11 41.7 29.5 1.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.26 VBB35497.1 - 1.8e-08 34.4 6.3 6.6e-05 23.1 0.2 4.9 5 0 0 5 5 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 VBB35497.1 - 6.8e-05 23.1 2.4 0.00031 21.0 0.4 4.1 4 0 0 4 4 3 2 Zinc-finger double domain DUF3824 PF12868.7 VBB35497.1 - 0.001 19.8 1.4 0.001 19.8 1.4 2.1 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) zf-C2H2_4 PF13894.6 VBB35497.1 - 0.002 18.8 6.5 0.053 14.4 1.4 5.4 5 0 0 5 5 3 2 C2H2-type zinc finger Roughex PF06020.11 VBB35497.1 - 0.0031 16.7 5.5 0.0041 16.3 5.5 1.1 1 0 0 1 1 1 1 Drosophila roughex protein GREB1 PF15782.5 VBB35497.1 - 0.013 12.7 26.0 0.016 12.3 26.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3439 PF11921.8 VBB35497.1 - 0.022 14.8 0.5 0.022 14.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Macoilin PF09726.9 VBB35497.1 - 0.026 13.1 22.2 0.031 12.9 22.2 1.1 1 0 0 1 1 1 0 Macoilin family zf-trcl PF13451.6 VBB35497.1 - 0.14 12.0 5.2 0.93 9.4 0.2 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-MYST PF17772.1 VBB35497.1 - 0.18 11.5 3.2 3.6 7.3 0.1 3.3 2 1 1 3 3 3 0 MYST family zinc finger domain SOBP PF15279.6 VBB35497.1 - 0.21 12.2 21.4 0.31 11.6 21.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein FAM76 PF16046.5 VBB35497.1 - 0.23 10.8 21.7 0.26 10.6 20.4 1.8 1 1 0 1 1 1 0 FAM76 protein DUF4471 PF14740.6 VBB35497.1 - 0.27 10.4 6.9 0.34 10.1 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) PAT1 PF09770.9 VBB35497.1 - 0.32 9.2 21.2 0.36 9.0 21.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 VBB35497.1 - 0.39 9.7 9.9 0.45 9.5 9.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2256 PF10013.9 VBB35497.1 - 0.45 10.7 2.6 10 6.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Lin-8 PF03353.15 VBB35497.1 - 0.69 9.4 14.4 0.87 9.1 14.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF966 PF06136.13 VBB35497.1 - 0.74 9.5 17.3 0.86 9.3 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFB6 PF17110.5 VBB35497.1 - 0.79 9.4 3.5 1.5 8.5 1.6 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF1387 PF07139.11 VBB35497.1 - 0.84 9.3 16.1 1 9.0 16.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 VBB35497.1 - 0.88 8.3 12.6 0.98 8.1 12.6 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 VBB35497.1 - 1 8.5 15.2 2.1 7.5 15.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.12 VBB35497.1 - 1 7.3 12.4 1.3 6.9 12.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FYVE_2 PF02318.16 VBB35497.1 - 1 9.6 8.6 0.063 13.5 3.0 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 VBB35497.1 - 1.2 9.4 3.8 2.4 8.3 1.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain Menin PF05053.13 VBB35497.1 - 1.4 7.2 13.1 1.8 6.9 13.1 1.1 1 0 0 1 1 1 0 Menin MMR1 PF08505.10 VBB35497.1 - 1.5 9.1 28.5 2.5 8.3 28.4 1.3 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein baeRF_family10 PF18854.1 VBB35497.1 - 1.6 9.0 13.3 3 8.1 13.3 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 CLN3 PF02487.17 VBB35497.1 - 1.6 7.7 5.4 2 7.3 5.4 1.3 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 VBB35497.1 - 4 6.2 11.7 5 5.8 11.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SPX PF03105.19 VBB35497.1 - 4.2 7.2 19.4 4.8 7.0 19.4 1.1 1 0 0 1 1 1 0 SPX domain WBP-1 PF11669.8 VBB35497.1 - 5.9 7.6 8.0 7.5 7.2 6.8 1.8 1 1 1 2 2 1 0 WW domain-binding protein 1 zf-C4_ClpX PF06689.13 VBB35497.1 - 6.3 6.8 8.0 7.6 6.5 0.6 2.8 2 1 0 2 2 2 0 ClpX C4-type zinc finger Paramyxo_ncap PF00973.19 VBB35497.1 - 10 4.9 7.0 11 4.8 7.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein GP46 PF07409.12 VBB35498.1 - 0.062 13.1 0.4 0.15 11.8 0.1 1.6 1 1 1 2 2 2 0 Phage protein GP46 DUF1759 PF03564.15 VBB35499.1 - 8.4e-24 84.2 0.3 1e-23 83.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) ANAPC4 PF12896.7 VBB35499.1 - 0.021 14.3 0.1 1.7 8.1 0.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 OAS1_C PF10421.9 VBB35500.1 - 0.17 11.4 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Collagen PF01391.18 VBB35501.1 - 7e-17 60.9 69.8 3.4e-09 36.3 34.1 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Adaptin_N PF01602.20 VBB35503.1 - 2.1e-17 62.9 0.4 2.3e-17 62.8 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 VBB35503.1 - 0.011 16.0 0.1 0.057 13.8 0.1 1.9 1 1 0 1 1 1 0 HEAT repeats MFS_1 PF07690.16 VBB35504.1 - 4.5e-11 42.3 0.7 4.6e-11 42.2 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Adaptin_N PF01602.20 VBB35506.1 - 3e-32 111.9 0.5 3.3e-32 111.7 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 VBB35506.1 - 0.0037 17.6 0.1 0.027 14.9 0.1 2.2 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 VBB35506.1 - 0.018 15.2 0.2 11 6.6 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 VBB35506.1 - 0.048 13.7 0.1 2.3 8.3 0.1 2.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 7tm_1 PF00001.21 VBB35508.1 - 1.1e-32 113.4 9.3 1.3e-32 113.1 9.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 VBB35508.1 - 0.00026 20.5 4.2 0.00032 20.2 4.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 VBB35508.1 - 0.0019 17.9 6.2 0.0025 17.5 6.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 VBB35508.1 - 0.0028 17.4 1.3 0.0049 16.6 1.3 1.5 1 1 0 1 1 1 1 Olfactory receptor Virul_fac_BrkB PF03631.15 VBB35508.1 - 0.009 15.7 0.6 0.0099 15.5 0.6 1.0 1 0 0 1 1 1 1 Virulence factor BrkB 7TM_GPCR_Srv PF10323.9 VBB35508.1 - 0.01 15.2 4.7 0.012 15.0 4.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv TPR_14 PF13428.6 VBB35509.1 - 0.0013 19.4 0.5 0.0035 18.0 0.5 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 VBB35509.1 - 0.002 18.1 1.6 0.053 13.6 0.8 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 VBB35509.1 - 0.0072 16.5 0.1 0.0083 16.3 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 VBB35509.1 - 0.011 15.9 0.6 0.061 13.6 0.4 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 VBB35509.1 - 0.019 15.3 1.1 0.13 12.5 1.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 VBB35509.1 - 0.03 14.1 1.7 0.056 13.3 0.8 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 VBB35509.1 - 0.055 14.0 0.1 0.062 13.8 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 VBB35509.1 - 0.086 13.3 0.1 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Laminin_G_3 PF13385.6 VBB35510.1 - 2.6e-07 30.9 0.2 3.5e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 VBB35510.1 - 0.00044 20.8 2.1 0.00093 19.7 2.1 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF FXa_inhibition PF14670.6 VBB35510.1 - 0.089 13.1 7.3 0.15 12.4 7.3 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 VBB35510.1 - 0.29 11.5 4.6 0.5 10.7 4.6 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.7 VBB35510.1 - 0.49 10.6 4.3 1.8 8.8 4.3 1.9 1 1 0 1 1 1 0 EGF domain SMC_N PF02463.19 VBB35511.1 - 5.9e-06 25.9 0.0 7.1e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 VBB35511.1 - 0.00083 19.5 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 VBB35511.1 - 0.0086 15.9 0.0 0.0098 15.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 VBB35511.1 - 0.033 12.9 0.1 0.036 12.7 0.1 1.0 1 0 0 1 1 1 0 AAA domain FXa_inhibition PF14670.6 VBB35512.1 - 1e-09 38.5 5.8 1e-09 38.5 5.8 2.5 4 0 0 4 4 4 1 Coagulation Factor Xa inhibitory site Sushi PF00084.20 VBB35512.1 - 1.6e-09 38.2 0.1 1.6e-09 38.2 0.1 2.0 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) EGF_CA PF07645.15 VBB35512.1 - 3e-08 33.7 7.7 3e-08 33.7 7.7 2.2 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 VBB35512.1 - 0.0008 19.7 5.0 0.0008 19.7 5.0 3.0 5 0 0 5 5 5 1 EGF-like domain EGF_3 PF12947.7 VBB35512.1 - 0.0013 18.9 5.5 0.0013 18.9 5.5 2.1 2 0 0 2 2 2 1 EGF domain DUF1759 PF03564.15 VBB35513.1 - 3.5e-27 95.2 0.2 5.8e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) zf-CCHC_4 PF14392.6 VBB35513.1 - 0.011 15.5 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 VBB35513.1 - 0.45 10.0 8.1 2.3 7.8 1.9 2.4 1 1 1 2 2 2 0 Copper fist DNA binding domain zf-CCHC_3 PF13917.6 VBB35513.1 - 0.91 9.5 11.7 0.26 11.3 6.2 2.3 1 1 1 2 2 2 0 Zinc knuckle Collagen PF01391.18 VBB35515.1 - 3.9e-11 42.5 29.5 6.9e-11 41.7 29.5 1.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) LIM PF00412.22 VBB35516.1 - 1.5e-10 41.2 0.2 1.6e-10 41.1 0.2 1.0 1 0 0 1 1 1 1 LIM domain zf-C2H2_7 PF15269.6 VBB35516.1 - 0.031 14.4 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger Herpes_UL87 PF03043.14 VBB35516.1 - 0.051 12.1 0.0 0.051 12.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Corona_S1 PF01600.16 VBB35517.1 - 0.11 11.3 0.1 0.099 11.4 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein E1-E2_ATPase PF00122.20 VBB35520.1 - 0.0051 16.3 0.0 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase A2M PF00207.22 VBB35520.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin family NOA36 PF06524.12 VBB35523.1 - 0.087 12.1 1.7 0.085 12.2 1.7 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 VBB35523.1 - 2.7 7.7 7.8 3 7.5 7.8 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1758 PF05585.12 VBB35524.1 - 5.7e-07 29.4 0.1 9e-07 28.8 0.0 1.4 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 VBB35524.1 - 0.035 14.7 0.0 0.085 13.5 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease Peptidase_A2B PF12384.8 VBB35524.1 - 0.074 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Ank_4 PF13637.6 VBB35525.1 - 1.7e-11 44.4 0.4 5.9e-05 23.5 0.1 3.1 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 VBB35525.1 - 1.5e-09 38.3 0.4 0.0018 18.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 VBB35525.1 - 4.1e-07 30.1 0.3 2 8.8 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 VBB35525.1 - 8.9e-06 25.7 0.7 0.6 10.8 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 VBB35525.1 - 0.00074 19.9 1.4 2.5 8.7 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat DUF1843 PF08898.10 VBB35525.1 - 0.014 15.8 0.2 0.038 14.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Myosin_head PF00063.21 VBB35526.1 - 1.5e-10 40.0 0.4 1.1e-09 37.2 0.4 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) FAR1 PF03101.15 VBB35526.1 - 0.02 15.6 0.1 0.035 14.8 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3135 PF11333.8 VBB35526.1 - 0.03 14.6 0.4 0.03 14.6 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Adaptin_N PF01602.20 VBB35528.1 - 4.8e-19 68.3 0.0 5.1e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 VBB35528.1 - 0.036 14.1 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PDE4_UCR PF18100.1 VBB35529.1 - 9.4e-29 100.5 0.0 1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) MOLO1 PF17175.4 VBB35530.1 - 4e-19 68.9 0.5 4.4e-19 68.8 0.5 1.0 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 Ribonuclease_P PF00825.18 VBB35531.1 - 0.00021 21.3 0.1 0.00023 21.2 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease P Sema PF01403.19 VBB35534.1 - 1.9e-31 109.3 0.0 2.4e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Sema domain Arrestin_N PF00339.29 VBB35535.1 - 6.6e-20 71.6 0.1 6.8e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 VBB35535.1 - 1.7e-07 31.7 0.1 6.5e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 VBB35535.1 - 0.047 12.9 0.0 0.093 11.9 0.0 1.5 2 0 0 2 2 2 0 Rgp1 Vps26 PF03643.15 VBB35535.1 - 0.059 12.4 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Transcrip_reg PF01709.20 VBB35535.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Transcriptional regulator EF-hand_1 PF00036.32 VBB35536.1 - 1.5e-10 39.9 4.0 0.013 15.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 VBB35536.1 - 7.5e-09 34.7 1.0 0.0056 16.1 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 VBB35536.1 - 5.9e-08 33.1 4.6 7.4e-05 23.1 0.8 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 VBB35536.1 - 4.7e-07 29.2 2.1 0.31 11.1 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 VBB35536.1 - 1.5e-06 27.9 4.1 0.0044 16.8 0.4 3.3 2 1 1 3 3 3 2 EF-hand domain pair DUF2774 PF11242.8 VBB35536.1 - 0.036 14.3 0.1 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Dockerin_1 PF00404.18 VBB35536.1 - 0.039 14.2 1.9 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I domain Guanylate_kin PF00625.21 VBB35537.1 - 2.6e-27 95.7 0.1 2.8e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase Collagen PF01391.18 VBB35538.1 - 6.4e-08 32.2 23.0 7.6e-08 32.0 23.0 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PDZ PF00595.24 VBB35539.1 - 0.0018 18.6 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 VBB35539.1 - 0.008 16.0 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 PDZ domain RE_Eco47II PF09553.10 VBB35540.1 - 0.036 13.7 0.0 0.04 13.5 0.0 1.0 1 0 0 1 1 1 0 Eco47II restriction endonuclease SH3_1 PF00018.28 VBB35541.1 - 7.6e-08 31.8 2.0 6.3e-07 28.9 1.3 2.4 2 1 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 VBB35541.1 - 1.5e-07 31.0 0.0 3.6e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 VBB35541.1 - 0.007 16.2 0.2 0.021 14.7 0.2 1.8 1 1 0 1 1 1 1 Variant SH3 domain Ephrin_lbd PF01404.19 VBB35542.1 - 5.9e-19 68.8 0.1 6.4e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain DUF5017 PF16409.5 VBB35542.1 - 0.059 12.8 0.1 0.07 12.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) Peptidase_C1 PF00112.23 VBB35543.1 - 2e-26 93.4 0.4 2.2e-26 93.3 0.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Collagen PF01391.18 VBB35545.1 - 6.6e-17 61.0 67.5 2.1e-09 37.0 31.7 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) LIM PF00412.22 VBB35547.1 - 1.9e-10 40.8 5.2 3.2e-10 40.1 5.2 1.4 1 1 0 1 1 1 1 LIM domain zf-B_box PF00643.24 VBB35547.1 - 0.74 10.0 7.2 4.3 7.6 0.6 3.0 3 0 0 3 3 3 0 B-box zinc finger zf-C2H2 PF00096.26 VBB35547.1 - 2.9 8.5 9.7 1.2 9.8 0.5 2.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Peptidase_A17 PF05380.13 VBB35549.1 - 5.3e-07 29.8 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase Chromadorea_ALT PF05535.12 VBB35550.1 - 2.3e-29 101.4 12.9 3e-29 101.0 12.9 1.1 1 0 0 1 1 1 1 Chromadorea ALT protein SEA PF01390.20 VBB35554.1 - 6.7e-08 32.6 0.0 7.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 SEA domain DUF1759 PF03564.15 VBB35555.1 - 5.3e-15 55.6 1.7 1.2e-06 28.5 0.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) Retrotran_gag_2 PF14223.6 VBB35555.1 - 6e-05 22.7 2.0 0.19 11.4 0.3 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type TerB_N PF13208.6 VBB35555.1 - 0.00065 19.5 1.7 0.26 11.0 0.2 2.0 2 0 0 2 2 2 2 TerB N-terminal domain Tropomyosin PF00261.20 VBB35555.1 - 0.013 14.9 2.1 1.3 8.3 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin Spc24 PF08286.11 VBB35555.1 - 0.014 15.7 2.1 3.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4600 PF15372.6 VBB35555.1 - 0.029 14.8 4.1 0.61 10.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DASH_Dad1 PF08649.10 VBB35555.1 - 0.035 14.3 0.5 9 6.6 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 Phage_GP20 PF06810.11 VBB35555.1 - 0.041 13.7 2.2 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 SF3b10 PF07189.11 VBB35555.1 - 0.049 13.8 0.9 6.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) SAND PF01342.21 VBB35555.1 - 0.058 13.1 0.3 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 SAND domain K-box PF01486.17 VBB35555.1 - 0.058 13.6 1.8 6.3 7.0 0.2 2.3 2 0 0 2 2 2 0 K-box region JIP_LZII PF16471.5 VBB35555.1 - 0.06 13.5 1.3 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II GvpO PF05800.11 VBB35555.1 - 0.068 13.1 0.0 6.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO DUF5113 PF17140.4 VBB35555.1 - 0.071 12.9 0.1 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Bul1_C PF04426.12 VBB35555.1 - 0.075 12.4 4.0 2.5 7.5 0.8 2.1 2 0 0 2 2 2 0 Bul1 C terminus KfrA_N PF11740.8 VBB35555.1 - 0.091 13.4 0.1 10 6.8 0.0 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term zf-CpG_bind_C PF12269.8 VBB35555.1 - 0.59 9.9 3.1 9.8 5.9 0.3 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Collagen PF01391.18 VBB35556.1 - 6.5e-12 45.0 44.1 7.1e-09 35.3 44.1 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 VBB35557.1 - 1.4e-14 53.5 64.7 1.3e-11 44.1 35.5 1.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Myosin_head PF00063.21 VBB35558.1 - 2.8e-48 164.7 0.0 3e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Bd3614-deam PF14439.6 VBB35559.1 - 0.17 12.0 0.6 0.17 12.0 0.6 1.1 1 0 0 1 1 1 0 Bd3614-like deaminase HCO3_cotransp PF00955.21 VBB35560.1 - 1.4e-22 80.2 0.2 1.6e-22 80.1 0.2 1.0 1 0 0 1 1 1 1 HCO3- transporter family BTG PF07742.12 VBB35563.1 - 6.2e-11 42.2 0.0 7.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 BTG family ELFV_dehydrog_N PF02812.18 VBB35564.1 - 1.5e-14 54.0 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glycoprotein_B PF00606.18 VBB35566.1 - 0.038 13.4 0.2 0.053 13.0 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain SID-1_RNA_chan PF13965.6 VBB35567.1 - 0.28 9.5 0.4 0.3 9.4 0.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RRN3 PF05327.11 VBB35567.1 - 2.6 6.5 6.3 2.9 6.3 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C2H2 PF00096.26 VBB35569.1 - 8.7e-05 22.8 0.1 0.00015 22.0 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB35569.1 - 0.00019 22.0 0.1 0.00037 21.1 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 VBB35569.1 - 0.00031 20.7 0.3 0.00031 20.7 0.3 1.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 VBB35569.1 - 0.00093 18.8 0.2 0.0011 18.6 0.2 1.2 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 VBB35569.1 - 0.0038 16.9 0.2 0.0077 16.0 0.2 1.6 1 1 0 1 1 1 1 C2H2-type zinc-finger domain DUF629 PF04780.12 VBB35569.1 - 0.0048 15.5 0.2 0.0061 15.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) NCD3G PF07562.14 VBB35569.1 - 0.013 15.5 1.8 0.013 15.5 1.8 1.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR zf-C2H2_12 PF18658.1 VBB35569.1 - 0.022 14.3 0.2 0.029 13.9 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type COQ7 PF03232.13 VBB35570.1 - 2.6e-14 53.3 0.1 2.9e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 E3_UbLigase_RBR PF18091.1 VBB35570.1 - 0.053 13.7 0.0 0.066 13.4 0.0 1.1 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain EGF PF00008.27 VBB35571.1 - 8.7e-09 35.5 11.3 6.4e-05 23.2 5.0 2.2 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 VBB35571.1 - 0.00015 22.3 7.0 0.0011 19.5 1.2 2.7 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.13 VBB35571.1 - 0.0018 18.6 13.8 0.01 16.2 1.5 2.2 2 0 0 2 2 2 2 EGF-like domain EGF_CA PF07645.15 VBB35571.1 - 0.014 15.6 11.8 0.079 13.2 6.7 2.2 1 1 1 2 2 2 0 Calcium-binding EGF domain Laminin_EGF PF00053.24 VBB35571.1 - 0.033 14.3 1.5 0.033 14.3 1.5 2.1 1 1 1 2 2 2 0 Laminin EGF domain EGF_3 PF12947.7 VBB35571.1 - 0.16 12.2 12.6 1.7 8.9 4.5 2.2 2 0 0 2 2 2 0 EGF domain cEGF PF12662.7 VBB35571.1 - 0.48 10.4 7.6 0.16 11.9 1.9 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 VBB35571.1 - 0.59 10.5 10.4 4.9 7.5 2.0 2.5 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Innexin PF00876.18 VBB35576.1 - 2.3e-08 33.7 0.0 2.4e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Innexin Actin PF00022.19 VBB35579.1 - 6.7e-25 87.5 0.0 7.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Actin UDPG_MGDP_dh_N PF03721.14 VBB35579.1 - 0.059 12.9 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Collagen PF01391.18 VBB35580.1 - 7.4e-16 57.7 64.2 8.2e-09 35.1 24.4 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) STPPase_N PF16891.5 VBB35581.1 - 2.6e-13 50.2 0.2 2.9e-13 50.0 0.2 1.0 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain I-set PF07679.16 VBB35583.1 - 4.3e-06 26.7 0.1 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 VBB35583.1 - 3e-05 24.5 0.6 0.03 14.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 VBB35583.1 - 0.0048 16.4 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Col_cuticle_N PF01484.17 VBB35584.1 - 5.8e-19 67.9 0.5 7e-19 67.6 0.5 1.1 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain IBV_3B PF03622.13 VBB35584.1 - 0.028 14.6 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 IBV 3B protein O-ag_pol_Wzy PF14296.6 VBB35584.1 - 0.031 12.9 0.1 0.035 12.8 0.1 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4199 PF13858.6 VBB35584.1 - 0.033 14.6 0.0 0.036 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2681 PF10883.8 VBB35584.1 - 0.082 13.3 2.0 1.9 9.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Peptidase_A17 PF05380.13 VBB35585.1 - 7.7e-31 107.3 0.1 9.3e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase RT_RNaseH_2 PF17919.1 VBB35585.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 VBB35585.1 - 0.051 13.9 0.1 0.091 13.1 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF1759 PF03564.15 VBB35586.1 - 1.6e-14 54.1 0.1 9.6e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) MFS_1 PF07690.16 VBB35587.1 - 0.011 14.7 0.9 0.012 14.6 0.9 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Band_7 PF01145.25 VBB35591.1 - 1.1e-09 38.5 2.5 1.3e-09 38.3 2.5 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family HHH_7 PF14635.6 VBB35591.1 - 0.076 13.4 0.1 0.085 13.2 0.1 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif CdiI PF07262.11 VBB35591.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 CDI immunity protein zf-H2C2_2 PF13465.6 VBB35592.1 - 1.6e-15 56.7 40.4 3.7e-07 30.3 3.4 4.9 4 1 1 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 VBB35592.1 - 2.2e-11 43.5 31.2 2.9e-06 27.4 1.4 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB35592.1 - 1.3e-07 31.8 34.6 0.00024 21.7 0.9 5.5 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 VBB35592.1 - 9.1e-06 25.5 31.9 0.00083 19.3 1.5 5.5 5 1 0 5 5 5 4 C2H2-type zinc finger zf_UBZ PF18439.1 VBB35592.1 - 0.0015 18.0 12.5 0.045 13.3 0.1 3.9 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 VBB35592.1 - 0.0018 18.6 29.9 0.011 16.0 0.5 6.1 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 VBB35592.1 - 0.01 16.1 0.4 0.01 16.1 0.4 5.8 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding UspB PF10625.9 VBB35592.1 - 0.097 12.6 7.1 1.1 9.2 0.3 3.1 1 1 1 3 3 3 0 Universal stress protein B (UspB) XPA_N PF01286.18 VBB35592.1 - 0.15 12.2 23.1 0.3 11.2 0.1 4.8 5 0 0 5 5 5 0 XPA protein N-terminal zf-AN1 PF01428.16 VBB35592.1 - 2.5 8.3 19.7 0.61 10.3 0.3 4.3 3 1 0 3 3 3 0 AN1-like Zinc finger HypA PF01155.19 VBB35592.1 - 6.2 6.9 14.8 0.94 9.5 1.6 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 VBB35592.1 - 9.2 6.6 19.6 9.7 6.5 9.8 4.1 1 1 2 3 3 3 0 TFIIH C1-like domain EGF PF00008.27 VBB35593.1 - 2.7e-12 46.7 20.8 9.3e-08 32.2 5.6 2.7 2 1 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 VBB35593.1 - 7.8e-07 29.4 20.4 0.0016 18.8 7.2 2.5 2 1 0 2 2 2 2 EGF-like domain hEGF PF12661.7 VBB35593.1 - 2.2e-06 28.1 13.9 8e-05 23.1 1.1 3.8 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_CA PF07645.15 VBB35593.1 - 1e-05 25.6 12.4 0.032 14.5 2.9 2.5 1 1 1 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 VBB35593.1 - 0.015 15.5 10.0 0.17 12.1 0.9 2.8 2 1 0 2 2 2 0 EGF domain EGF_alliinase PF04863.13 VBB35593.1 - 0.02 15.3 16.5 0.061 13.7 5.7 3.2 2 2 0 2 2 2 0 Alliinase EGF-like domain EGF_MSP1_1 PF12946.7 VBB35593.1 - 0.022 14.8 13.5 0.55 10.3 3.7 2.8 2 1 0 2 2 2 0 MSP1 EGF domain 1 Laminin_EGF PF00053.24 VBB35593.1 - 0.024 14.8 18.0 0.81 9.9 3.3 2.6 1 1 1 2 2 2 0 Laminin EGF domain Metallothi_Euk2 PF12809.7 VBB35593.1 - 0.11 12.8 14.6 0.09 13.1 4.6 2.3 1 1 1 2 2 2 0 Eukaryotic metallothionein EB PF01683.18 VBB35593.1 - 0.41 11.0 14.4 0.43 10.9 2.1 2.6 1 1 1 2 2 2 0 EB module FXa_inhibition PF14670.6 VBB35593.1 - 0.65 10.3 15.7 0.91 9.9 2.6 2.9 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 VBB35593.1 - 5 7.2 15.3 2.7 8.0 0.5 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like EGF_Tenascin PF18720.1 VBB35593.1 - 5.9 7.1 10.4 0.27 11.3 3.3 2.5 3 1 0 3 3 2 0 Tenascin EGF domain Collagen PF01391.18 VBB35597.1 - 1.7e-09 37.3 22.6 2e-09 37.1 22.6 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-H2C2_2 PF13465.6 VBB35599.1 - 2.2e-37 125.8 26.1 2e-07 31.1 0.1 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 VBB35599.1 - 1.7e-25 88.0 29.2 1.6e-05 25.1 0.3 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 VBB35599.1 - 7e-20 70.0 27.0 0.0013 19.4 1.0 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 VBB35599.1 - 4.2e-14 52.4 22.5 0.0089 16.4 0.4 5.4 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 VBB35599.1 - 2.6e-13 49.6 28.4 0.00021 21.2 0.1 5.5 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 VBB35599.1 - 3.9e-07 30.2 19.5 0.41 11.0 0.0 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding Desulfoferrod_N PF06397.12 VBB35599.1 - 6.2e-07 28.9 21.3 0.49 10.1 0.4 5.5 5 0 0 5 5 5 3 Desulfoferrodoxin, N-terminal domain zf-Di19 PF05605.12 VBB35599.1 - 3.4e-05 24.0 15.0 0.0014 18.9 0.4 3.4 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 VBB35599.1 - 5.4e-05 23.1 25.9 0.043 13.9 2.6 5.2 1 1 4 5 5 5 2 BED zinc finger zf-C2H2_8 PF15909.5 VBB35599.1 - 6.8e-05 23.1 12.6 0.0075 16.5 1.5 3.2 1 1 3 4 4 4 4 C2H2-type zinc ribbon BolA PF01722.18 VBB35599.1 - 0.00037 20.7 0.1 0.73 10.2 0.2 3.9 1 1 1 2 2 2 1 BolA-like protein Prok-RING_1 PF14446.6 VBB35599.1 - 0.00088 19.2 16.2 5.4 7.0 0.0 5.2 4 1 1 5 5 5 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 VBB35599.1 - 0.00094 19.3 20.9 0.96 9.6 0.1 4.9 3 1 2 5 5 5 3 Zinc ribbon domain DUF3268 PF11672.8 VBB35599.1 - 0.0026 18.1 13.8 0.0056 17.0 1.2 2.8 1 1 1 3 3 3 2 zinc-finger-containing domain zf_UBZ PF18439.1 VBB35599.1 - 0.0035 16.9 13.6 8.7 6.0 0.1 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 VBB35599.1 - 0.0053 16.8 16.9 0.03 14.3 2.3 3.5 1 1 3 4 4 4 3 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 VBB35599.1 - 0.0074 16.3 15.4 9 6.4 0.1 5.3 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 VBB35599.1 - 0.013 15.2 16.9 2.7 7.8 0.1 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type C1_4 PF07975.12 VBB35599.1 - 0.015 15.5 18.6 0.97 9.7 1.2 4.4 1 1 4 5 5 5 0 TFIIH C1-like domain C1_2 PF03107.16 VBB35599.1 - 0.037 14.3 25.9 3.8e+02 1.5 11.4 5.2 1 1 1 2 2 2 0 C1 domain zf-C2H2_3rep PF18868.1 VBB35599.1 - 0.038 14.7 19.2 10 6.8 0.1 4.9 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats Vps36-NZF-N PF16988.5 VBB35599.1 - 0.044 13.2 8.0 0.052 12.9 0.1 3.2 3 1 1 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_15 PF17032.5 VBB35599.1 - 0.047 14.4 14.4 0.29 11.9 0.9 3.0 1 1 2 3 3 3 0 zinc-ribbon family PyrI_C PF02748.15 VBB35599.1 - 0.072 13.0 18.0 0.7 9.8 0.3 5.1 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_L28 PF00830.19 VBB35599.1 - 0.091 13.0 16.5 2.8 8.2 0.1 5.1 5 0 0 5 5 5 0 Ribosomal L28 family FYVE PF01363.21 VBB35599.1 - 0.11 12.7 27.4 11 6.3 9.0 4.3 1 1 1 2 2 1 0 FYVE zinc finger Zf_RING PF16744.5 VBB35599.1 - 0.12 12.5 16.3 13 6.0 0.8 5.0 1 1 4 5 5 5 0 KIAA1045 RING finger zf-AN1 PF01428.16 VBB35599.1 - 0.64 10.2 26.0 27 5.0 2.8 5.3 4 1 1 5 5 5 0 AN1-like Zinc finger zf-Mss51 PF13824.6 VBB35599.1 - 0.67 10.1 18.6 4.8 7.4 0.2 5.0 4 1 1 5 5 5 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2175 PF09943.9 VBB35599.1 - 0.78 10.1 14.6 21 5.5 0.0 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2175) PHF5 PF03660.14 VBB35599.1 - 1.1 9.5 11.1 5.3 7.3 3.6 2.8 1 1 1 2 2 2 0 PHF5-like protein PHD PF00628.29 VBB35599.1 - 1.3 9.0 18.4 0.073 13.0 3.0 3.5 2 1 1 3 3 3 0 PHD-finger DUF3449 PF11931.8 VBB35599.1 - 1.6 8.5 25.9 2.4 7.9 0.3 4.9 2 2 3 5 5 5 0 Domain of unknown function (DUF3449) PhnA_Zn_Ribbon PF08274.12 VBB35599.1 - 1.8 8.6 7.7 2.2 8.3 0.2 3.9 4 1 0 4 4 4 0 PhnA Zinc-Ribbon zf-trcl PF13451.6 VBB35599.1 - 2.1 8.3 16.7 41 4.2 0.3 5.2 5 0 0 5 5 5 0 Probable zinc-ribbon domain DUF2256 PF10013.9 VBB35599.1 - 2.4 8.3 14.5 46 4.2 0.1 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 VBB35599.1 - 3.9 7.2 13.7 4.1 7.1 0.2 4.5 1 1 4 5 5 5 0 MYST family zinc finger domain CpXC PF14353.6 VBB35599.1 - 4.2 7.4 14.2 19 5.3 0.1 4.7 3 1 2 5 5 5 0 CpXC protein Ribosomal_L37ae PF01780.19 VBB35599.1 - 7.9 6.6 19.5 1.5 9.0 4.0 4.5 1 1 3 4 4 4 0 Ribosomal L37ae protein family HNH PF01844.23 VBB35599.1 - 8.5 6.6 23.2 28 5.0 0.9 5.3 5 0 0 5 5 5 0 HNH endonuclease Frankia_peptide PF14407.6 VBB35602.1 - 0.081 12.9 1.1 0.74 9.8 0.2 2.6 1 1 1 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF1758 PF05585.12 VBB35603.1 - 1.7e-07 31.2 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase (DUF1758) zf-H2C2_2 PF13465.6 VBB35604.1 - 4.7e-08 33.1 5.6 0.0003 21.1 1.6 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 VBB35604.1 - 1.8e-06 28.1 2.1 1.8e-06 28.1 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 VBB35604.1 - 0.00054 19.9 0.3 0.00054 19.9 0.3 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 VBB35604.1 - 0.00061 20.4 0.8 0.00061 20.4 0.8 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Acanthocheilonema_viteae-ASM90053725v1/GCA_900537255.1_ASM90053725v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Acanthocheilonema_viteae-ASM90053725v1/GCA_900537255.1_ASM90053725v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Acanthocheilonema_viteae-ASM90053725v1/GCA_900537255.1_ASM90053725v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Nematods/Acanthocheilonema_viteae-ASM90053725v1/GCA_900537255.1_ASM90053725v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 17:48:10 2019 # [ok]